Digital Commons Network^™

Winter Field Report, December 2024–February 2025, W. Ross Silcock

Nebraska Bird Review

Since I started a few years ago to compare each season’s reports with the status of each species as presented in BONO (Species Accounts – Birds of Nebraska – Online), I had expected that “Routine reports” would apply to an increasing number of species as the BONO database firmed up, but this hasn’t happened. My comments from last winter continue to be valid this winter, now for the third winter in a row: As was the case for winter 2022–2023, the big general story was the large number of reports of tardy fall migrants and unexpectedly northerly occurrences in mid-winter… …

Une Library Services Quarterly Report March 2025, Une Library Services

Quarterly Reports

Highlights of accomplishments of the University of New England's Library Services department.

Alfred Russel Wallace Notes 35. Natural Selection By Evolution., Charles H. Smith

Faculty/Staff Personal Papers

Alfred Russel Wallace (1823?1913) is remembered, with Charles Darwin, as the co-originator of the concept of evolution by natural selection. But Wallace’s framing of the idea increasingly became one in which natural selection itself was regarded as a law of nature, not a theory per se.

Collaborative Ai: Oer Materials For Exploring Ai As A Partner Rather Than A Tool, David Smith

Open Educational Resources

The Collaborative AI Open Educational Resource (OER) explores how artificial intelligence can act as a creative and analytical collaborator rather than a tool. Centered on the Balanced Blended Space (BBS) framework and the philosophy of the Center for Holistic Integration (CHI), the OER includes curriculum materials, theoretical models, and live research environments. It offers an interesting approach to blending physical, virtual, and conceptual spaces through shared human–AI agency and invites ongoing participation in interdisciplinary meta-projects.

March 2025 Library & Learning Newsletter, Minnesota State University, Mankato. Library & Learning Dean’S Office Communications Team

Library & Learning Newsletters

PDF version of the March 2025 (Volume 3, Issue 5) Library & Learning Newsletter.

Ml-Urinequant: A Machine Learning Program For Identifying And Quantifying Mouse Urine On Absorbent Paper., Warren G Hill, Bryce Maciver, Gary Churchill, Mariana G Deoliveira, Mark L Zeidel, Marcelo Cicconet

Faculty Research 2025

The void spot assay has gained popularity as a way of assessing functional bladder voiding parameters in mice, but analyzing the size and distribution of urine spot patterns on filter paper with software remains problematic due to inter-laboratory differences in image contrast and resolution quality and non-void artifacts. We have developed a machine learning algorithm based on Region-based Convolutional Neural Networks (Mask-RCNN) that was trained in object recognition to detect and quantitate urine spots across a broad range of sizes-ML-UrineQuant. The model proved extremely accurate at identifying urine spots in a wide variety of illumination and contrast settings. The overwhelming …

Predicting The Impact Of Rare Variants On Rna Splicing In Cagi6., Jenny Lord, Carolina Jaramillo Oquendo, Htoo A Wai, Andrew G L Douglas, David J Bunyan, Yaqiong Wang, Zhiqiang Hu, Zishuo Zeng, Daniel Danis, Panagiotis Katsonis, Amanda Williams, Olivier Lichtarge, Yuchen Chang, Richard D Bagnall, Stephen M Mount, Brynja Matthiasardottir, Chiaofeng Lin, Thomas Van Overeem Hansen, Raphael Leman, Alexandra Martins, Claude Houdayer, Sophie Krieger, Constantina Bakolitsa, Yisu Peng, Akash Kamandula, Predrag Radivojac, Diana Baralle

Faculty Research 2025

Variants which disrupt splicing are a frequent cause of rare disease that have been under-ascertained clinically. Accurate and efficient methods to predict a variant's impact on splicing are needed to interpret the growing number of variants of unknown significance (VUS) identified by exome and genome sequencing. Here, we present the results of the CAGI6 Splicing VUS challenge, which invited predictions of the splicing impact of 56 variants ascertained clinically and functionally validated to determine splicing impact. The performance of 12 prediction methods, along with SpliceAI and CADD, was compared on the 56 functionally validated variants. The maximum accuracy achieved was …

Cascades, A Novel Sox2 Super-Enhancer-Associated Long Noncoding Rna, Regulates Cancer Stem Cell Specification And Differentiation In Glioblastoma., Uswa Shahzad, Marina Nikolopoulos, Christopher Li, Michael Johnston, Jenny J Wang, Nesrin Sabha, Frederick S Varn, Alexandra Riemenschneider, Stacey Krumholtz, Pranathi Meda Krishnamurthy, Christian A Smith, Jason Karamchandani, Jonathan K Watts, Roel G W Verhaak, Marco Gallo, James T Rutka, Sunit Das

Faculty Research 2025

Glioblastoma is the most common primary malignant brain tumor in adults, with a median survival of just over 1 year. The failure of available treatments to achieve remission in patients with glioblastoma (GBM) has been attributed to the presence of cancer stem cells (CSCs), which are thought to play a central role in tumor development and progression and serve as a treatment-resistant cell repository capable of driving tumor recurrence. In fact, the property of "stemness" itself may be responsible for treatment resistance. In this study, we identify a novel long noncoding RNA (lncRNA), cancer stem cell-associated distal enhancer of SOX2 …

Melanocortin 4 Receptor-Dependent Mechanism Of Acth In Preventing Anxiety-Like Behaviors And Normalizing Astrocyte Proteins After Early Life Seizures., Mohamed R Khalife, Colin Villarin, Juan Manuel Ruiz, Sam A Mcclelland, Khalil Abed Rabbo, J Matthew Mahoney, Rod C Scott, Amanda E Hernan

Faculty Research 2025

Epilepsy, affecting millions globally, often leads to significant cognitive and psychiatric comorbidities, particularly in children. Anxiety and depression are particularly prevalent, with roughly a quarter of pediatric epilepsy patients having a comorbid diagnosis. Current treatments inadequately address these issues. Adrenocorticotropic hormone (ACTH), a melanocortin peptide, has shown promise in mitigating deficits after early-life seizures (ELS), potentially through mechanisms beyond its canonical action on the melanocortin 2 receptor. This study explores the hypothesis that recurrent ELS is associated with long-term anxiety and that treatment with ACTH can prevent this anxiety through a mechanism that involves the melanocortin 4 receptor (MC4R) in …

Real-Time Prediction Of Dynamical Systems Using A Hybrid Analog Computer: Network Traffic Modeling, Majd Zuhair Tahat

Doctoral Dissertations

As the number of online users grows exponentially, the number and severity of cyber threats escalate, urgently requiring advancements in real-time network modeling and response. Swiftly predicting and analyzing network traffic is crucial for effective network monitoring and control, preventing cyber breaches, and maintaining healthy network functionality. This research presents a novel approach to real-time modeling based on analyzing evolving properties and patterns in a dynamical network system using a hybrid analog-digital computer. An analog computer was utilized as a co-processor to compute differential equations that model the Transmission Control Protocol (TCP) window size. A comparative analysis was conducted between …

A Human-In-The-Loop Framework For Scalable And Interpretable Event Triaging In Large-Scale Systems, Ibrahim Khaled Al-Agha

Doctoral Dissertations

This dissertation presents a comprehensive and scalable framework for real-time fault detection and event triage in industrial systems, addressing critical challenges such as class imbalance, ambiguous feature boundaries, and the prioritization of complex, high-dimensional event data. The proposed framework integrates advanced methodologies, including micro-batch processing, retrospective divergence-based event detection (DB-RED), association rule mining (ARM), clustering, and Dempster-Shafer Theory (DST) for conflict resolution. Together, these components enable the systematic stratification of events into actionable priority levels, ensuring robust and interpretable decision-making in real-time environments. DB-RED forms the cornerstone of the framework, leveraging KL-divergence and PE-divergence metrics to detect subtle and transient …

A Preliminary Report Of The Carotenoid Assessment In Adults 50 Years Of Age And Older In Louisiana, Mary-Catherine Feazell

Master's Theses

Fruits and vegetables are at the core of a healthy, balanced diet. They assist in preventing the development of chronic diseases such as hypertension, diabetes, cardiovascular disease, and cancer (Fadnes, et al., 2022). Aging is a natural biological process followed by disease, cognitive impairment, and a natural decline of the body’s ability to perform at its best. The older adult population is currently the fastest-growing population globally (El-Shebiney et al., 2022). Vitamin A is crucial for several parts of the body to function correctly. Despite the positive effects of Vitamin A on the body, the recommended dietary intake is not …

Understanding Brand Perception And Purchase Drivers Among Engaged Stakeholders For Products Developed At The University Of The Philippines Los Baños, Emil John C. Cabrera, Eunice Dianne Y. Algar, Cathrene P. Amante, Rainielle Kyle M. Guison

Asia-Pacific Intellectual Property Management and Innovation Book Series

Branding for universities is a relatively new concept, particularly as they position themselves to be an “entrepreneurial university.” This model necessitates a proactive approach to intellectual property (IP) management and technology transfer. Recent studies on university branding focus on higher educational institutions (HEIs) and how branding supports the development of their distinct identities and reputation. However, research on the perception of university-developed products, particularly in the context of the Philippines, is still limited. This study, therefore, examined the brand perceptions and purchase drivers of engaged stakeholders towards University of the Philippines Los Baños (UPLB)-developed products to evaluate the effectiveness of …

Ecology Of Ixodes Scapularis Say: Experimental And Observational Studies With Social Perspectives On Ticks And Tick-Borne Diseases, Kaitlin M. Mcdonald

Dartmouth College Ph.D Dissertations

Tick-borne diseases are a growing concern globally. Understanding the factors that influence tick ecology and people’s understanding of that ecology is crucial for developing effective tick management and disease prevention strategies. In this work, I investigated fundamental questions about the ecology of a primary vector of medically important pathogens in the United States, the blacklegged tick Ixodes scapularis Say, and identified common misconceptions about ticks and tick-borne diseases on social media. First, I examined the effects of temperature and moisture stress on the movement of adult female I. scapularis in laboratory experiments. Using a Drosophila Activity Monitor, ticks were exposed …

Optimizing Biofungicide Use In Managing Winegrape Powdery Mildew On The Central Coast Of California, Edgar G. Godoy Monterroso

Master's Theses

Grapevine powdery mildew caused by the fungal pathogen Erysiphe necator is a persistent threat to wine grape production in California. While synthetic fungicides remain the primary management strategy, increasing concerns over pesticide resistance, environmental impact, and regulatory restrictions have driven interest in biofungicides as a sustainable alternative. However, their efficacy is inconsistent, requiring research into optimized application strategies, integration with synthetic fungicides, and their effects on disease suppression, grape yield, and fruit quality.

This two-year study (2023–2024) was conducted at two vineyard sites, Trestle Vineyard in the San Luis Obispo Coast AVA and a commercial vineyard in the Arroyo Grande …

Brain-Type Natriuretic Peptide Is A Useful Biomarker Of Cardiovascular Disease And Predictor Of Cardiac-Related Mortality In Chimpanzees (Pan Troglodytes), Angela M. Achorn, Carolyn L. Hodo, Martha E. Hensel, Elizabeth R. Magden, Stephanie J. Buchl

Anthropology Faculty Publications

OBJECTIVE

To validate the use of brain-type natriuretic peptide (BNP) for detecting and monitoring cardiac dysfunction in captive chimpanzees (Pan troglodytes).

METHODS

We analyzed cross-sectional (N = 175) and longitudinal (N = 76) BNP, echocardiogram, ECG, and pathology data from living and deceased captive chimpanzees to examine age and sex effects and to assess the usefulness of BNP for detecting cardiovascular disease and predicting mortality. The study period was from July 2010 through October 2024.

RESULTS

Brain-type natriuretic peptide values were significantly associated with age, and males exhibited significantly higher BNP values than females. Brain-type natriuretic peptide values …

Can Oral Caffeine Decrease Postoperative Opioid Consumption Following Posterior Spinal Fusion In Adolescent Idiopathic Scoliosis? A Randomized Placebo-Controlled Trial., Anne E. Stuedemann, Richard M. Schwend, K Aaron Shaw, Nicolette Saddler, Michon Huston, Michael Benvenuti, Julia Leamon, Ashley K. Sherman, John Anderson

Manuscripts, Articles, Book Chapters and Other Papers

BACKGROUND: Current studies have examined the efficacy of opioid-sparing analgesics primarily in adult surgical populations, while fewer guide pediatric postoperative pain treatment. Caffeine exerts most of its biological effects by binding to adenosine receptors, which are important for modifying pain and inflammation. Caffeine's ability to modulate pain following posterior spinal fusion (PSF) for adolescent idiopathic scoliosis (AIS) has not been previously assessed.

METHODS: The hospital investigational drug study (IDS) pharmacy provided either a treatment dose or placebo dose of caffeine to be given to the patient and was also in charge of randomization for the study.

RESULTS: There were 24 …

The Anchor: March 2025, Issue Three, Hope College

The Anchor: 2025

The Anchor began in 1887 and was first issued weekly in 1914. Covering national and campus news alike, Hope College’s student-run newspaper has grown over the years to encompass over two-dozen editors, reporters, and staff. For much of The Anchor's history, the latest issue was distributed across campus each Wednesday throughout the academic school year (with few exceptions). In recent years The Anchor moved to monthly print issues and a more frequently updated website. The Anchor is now published in print twice per academic semester. Occasionally, the volume and/or issue numbering is irregular.

Lshe/Cse And Srh Linkages: The Role Of Health Care Providers, Population Council

Sexual and Reproductive Health, Rights, and Choices

No abstract provided.

Efficacy Of Immersive Virtual Reality Gameplay In Environmental Attitude Change: The Case Of Abandoned Offshore Oil Platforms In Santa Barbara, Arun Prasad Srinivasan Manoharan

Master's Theses

Public perception plays an important role in shaping conservation policies and decisions, especially in contested environmental spaces. Offshore oil platforms, historically viewed as environmental hazards, have been found to serve as marine habitats that support diverse marine life. However, public perception remains largely negative, influenced by concerns over pollution from past oil spill accidents. Traditional environmental education methods, such as lectures and documentaries, often fail to engage audiences effectively or shift entrenched opinions. This study explores the efficacy of immersive Virtual Reality (VR) gameplay in changing environmental attitudes, specifically in the context of abandoned offshore oil platforms in Santa Barbara, …

Defining Transcriptional Signatures Of Susceptibility For Ceftriaxone And Tetracycline In Neisseria Gonorrhoeae, Sanjana Logu

Theses

Resistance to antibiotics is the ability of bacteria to survive in spite of the administration of drugs designated to kill them; and overuse of antibiotics over the past decades has led to a vast increase in resistance. Most infections are treated empirically, such that patients are given a recommended course of antibiotics, however these infections are not frequently tested for their antimicrobial susceptibility profiles (i.e., tested only in the case of treatment failure). This can lead to inappropriate prescription which can increase the selective pressure of antibiotics on other bacterial members of our microbiomes. Susceptibility testing would help determine the …

Preparation Of Eco-Friendly Nanocatalyst Calcium Oxide (Cao) For Oily Wastewater Treatment By Advanced Oxidation Process, Eman Khader, Thamer Mohammed, Talib Albayati, Sohrab Zendehboudi

Journal of Applied Sciences and Nanotechnology

In the present work, a novel eco-friendly nanocatalyst (NC) calcium oxide (CaO) is synthesized from the waste of tomato plants by physical method for the degradation of oil in oily wastewater by photocatalytic technology as a sophisticated oxidation process. The characterization of NC prepared is described by dynamic light scattering (DLS), Brunauer-Emmett-Teller (BET) analysis, Fourier transform infrared spectroscopy (FTIR), field emission scanning electron microscopy (FE-SEM), X-ray powder diffraction (XRD), and energy-dispersive X-ray (EDX) spectroscopy, which illustrated that the NC prepared possessed a nanoscale size and a cubic crystal structure. The activity of NC in the photodegradation process is evaluated using …

Laser-Induced Breakdown Spectroscopy: Principles And Advanced Applications, Rajaa Ketan, Muayyed Zoory, Haidar Mohamad

Journal of Applied Sciences and Nanotechnology

A spectroscopic technique such as laser-induced breakdown spectroscopy (LIBS) is used to analyze various materials, including solids, liquids and gases. The advantages of this technique include rapid analysis, no prior sample preparation, low cost and the ability to generate qualitative and quantitative analytical data for any sample. There are numerous applications for LIBS in various fields, including environmental monitoring, quality in industry, the food sector and archeology, medicine (pharmaceuticals), biology (bones, nails, hair, blood and skin) and cosmetics, which is one of the main concerns of the World Health Organization due to its significant impact on health. In this review, …

Among-Population Variation In Telomere Regulatory Proteins And Their Potential Role As Hidden Drivers Of Intraspecific Variation In Life History, Sarah E. Wolf, Mary J. Woodruff, David A. Chang Van Oordt, Ethan D. Clotfelter, Daniel A. Cristol, Elizabeth P. Derryberry, Stephen M. Ferguson, Mark T. Stanback, Conor C. Taff, Maren N. Vitousek, David F. Westneat, Kimberly A. Rosvall

Biology Faculty Publications

Biologists aim to explain patterns of growth, reproduction and ageing that characterize life histories, yet we are just beginning to understand the proximate mechanisms that generate this diversity. Existing research in this area has focused on telomeres but has generally overlooked the telomere's most direct mediator, the shelterin protein complex. Shelterin proteins physically interact with the telomere to shape its shortening and repair. They also regulate metabolism and immune function, suggesting a potential role in life history variation in the wild. However, research on shelterin proteins is uncommon outside of biomolecular work. Intraspecific analyses can play an important role in …

Macroevolutionary Inference Of Complex Modes Of Chromosomal Speciation In A Cosmopolitan Plant Lineage, Carrie M. Tribble, José Ignacio Márquez-Corro, Michael R. May, Andrew L. Hipp, Marcial Escudero, Rosana Zenil-Ferguson

Biology Faculty Publications

The effects of single chromosome number change—dysploidy – mediating diversification remain poorly understood. Dysploidy modifies recombination rates, linkage, or reproductive isolation, especially for one-fifth of all eukaryote lineages with holocentric chromosomes. Dysploidy effects on diversification have not been estimated because modeling chromosome numbers linked to diversification with heterogeneity along phylogenies is quantitatively challenging. We propose a new state-dependent diversification model of chromosome evolution that links diversification rates to dysploidy rates considering heterogeneity and differentiates between anagenetic and cladogenetic changes. We apply this model to Carex (Cyperaceae), a cosmopolitan flowering plant clade with holocentric chromosomes. We recover two distinct modes of …

Scaling Covid-19 Rates With Population Size In The United States, Austin R. Cruz, Brian J. Enquist, Joseph R. Burger

Biology Faculty Publications

Using county-level data from the United States, we assessed allometric scaling relationships of coronavirus disease (COVID-19) cases, deaths and age structure within and across the first four major waves of the pandemic (wild-type, alpha, delta, omicron). Results generally indicate that the burden of cases disproportionately impacted larger-sized counties, while the burden of deaths disproportionately impacted smaller counties. This may be partially due to multiple interacting social mechanisms, including a higher proportion of older adults who live in smaller counties. Moreover, these likely social mechanisms interacting with vaccinations and virus waves created a dynamic pattern whereby the rate and magnitude of …

The Biphasic Effect Of Lipopolysaccharide On Membrane Potential, Maria E. Hadjisavva, Robin L. Cooper

Biology Faculty Publications

Lipopolysaccharide (LPS) from certain strains of Gram-negative bacteria can induce a rapid (<1 s) hyperpolarization of membrane potential, followed by a gradual depolarization exceeding the initial resting membrane potential. Through overexpression of a Drosophila ORK1 two-pore-domain K⁺ channel (K2P) in larval muscles and altering the external concentrations of K⁺ and Na⁺ ions, it is clear that the hyperpolarization is due to activating K2P channels and the depolarization is due to promoting an inward Na⁺ leak. When the external Na⁺ concentration is negligible, the LPS-delayed depolarization is dampened. The hyperpolarization induced by LPS can exceed −100 mV when external K⁺ and Na⁺ concentrations are lowered. These results indicate direct action by LPS on ion channels independently of immune …

Wright State University's Celebration Of Student Research, Scholarship & Creative Activities From Thursday, March 13, 2025, Wright State University

Celebration of Undergraduate & Graduate Research, Scholarship, and Creative Activities Abstract Books

The student abstract booklet is a compilation of abstracts from students' oral and poster presentations at Wright State University's Celebration of Student Research, Scholarship & Creative Activities on March 13, 2025.

Cold Chain Logistics Optimization: Integrating Iot And Data Analytics To Reduce Post-Harvest Loss In The United States Perishable Food Supply Chain: A Case Study Of Dole Food Company, Sarah Onyeche Usoro, Elizabeth Ramatu Galadima, Onyeche Helen Adogwa

Student Publications

Food spoilage in the United States is not simply a logistical inconvenience. It is one of the most underappreciated sources of economic and environmental waste in the country's food system. Fruits, vegetables, dairy products, and meat are routinely lost during storage and transport not because operators lack the will to prevent it, but because conventional cold chain management has historically lacked the tools to detect and respond to deteriorating conditions before damage becomes irreversible. This paper examines how the convergence of Internet of Things (IoT) sensing networks and data analytics platforms is reshaping what cold chain operators can know, predict, …

Workforce Forecasting For State Transportation Agencies: A Machine Learning Approach, Adedolapo Ogungbire, Suman Kumar Mitra

Civil Engineering Faculty Publications and Presentations

A decline in the number of construction engineers and inspectors at state transportation agencies (STAs) to manage the ever-increasing lane miles has emphasized the importance of workforce planning in these agencies. Forecasting workforce requirements is crucial for effective planning in any industry or agency. This study developed machine learning (ML) models to estimate the person-hour requirements of STAs at the project level. The Arkansas Department of Transportation (ARDOT) was used as a case study, using its employee and project details data between 2012 and 2021. ML regression models ranging from linear, tree ensembles, kernel-based, and neural network-based models were …