Digital Commons Network^™

Longitudinal Changes In Aerodigestive Responses To Varying Nipple Properties In Infant Pigs, François D H Gould, Christopher Mayerl, Khaled Adjerid, Jessica Reibel, Nichole Charles, Chloe Edmonds, Rebecca Z German

Rowan-Virtua School of Osteopathic Medicine Departmental Research

Coordination of respiration and swallowing is critical for survival in infant mammals and changes throughout infant maturation. Infants show sensorimotor feeding responses to changes in physical properties of nipples. Commercial nipples are promoted as improving aerodigestive coordination. However, it is unknown how nipple properties influence coordination of respiration and swallowing. Furthermore, how infant-nipple interactions change throughout maturation is not well understood. We designed and manufactured four silicone nipples of the same shape that varied in two parameters: nipple opening diameter and nipple stiffness. We used our validated infant pig model to test the impact of nipple parameters on aerodigestive coordination …

Grounded In Touch: The Science Behind Anxiety Relief And Human Connection, Misty Rhoads Ph.D. Czb, Mary Murphy M.A., Lmt, Czb, Mary L. Behrens Pt, Czb, Rhonda Salvo Pt, Czb, Sarah-Elizabeth Anderson Lmt, Czb, Clare Gowen Pt, Czb, Dawn Humbles Lsh, Czb, Veronica Quarry Pt, Czb, Deborah Rosene Ph.D., Czb, Wendy Tribelhorn Lmt, Czb, Jared Urcheck L.Ac, Czb, Deanna Waggy Otr, Czb

Journal of Transformative Touch

Background: Anxiety disorders are among the most pervasive mental health challenges worldwide, affecting individuals across all demographics and socioeconomic backgrounds. As a leading contributor to disability and diminished quality of life, anxiety continues to rise in prevalence, exacerbated by global crises and societal stressors. This study explored how Zero Balancing (ZB) supports individuals with anxiety. Researchers hypothesized that ZB would lower the perceived severity of general anxiety and reduce perceived anxiety symptoms.

Methods: A concurrent mixed-methods phenomenological research design was utilized to honor the holistic nature of bodywork and explore participants' lived experiences. This national study involved 320 ZB sessions …

Behavior Of Rio Sao Francisco Piranhas In Response To Changes In Space And Density, Ronald G. Oldfield, Josie E. Thal, Kristen E. Lukas

Faculty Scholarship

Previous observations of Rio Sao Francisco piranhas (Pygocentrus piraya) at Cleveland Metroparks Zoo revealed frequent aggressive interactions, which were associated with the injury and death of some individuals. Fishes are known to increase aggressive behavior when available space is limited. We compared the behavior of the piranhas longitudinally across three different space/density conditions: (1) in a group held in a small aquarium before the death of one individual, (2) in the same group after the death of one individual, (3) and in one individual of the group after it was later moved into a larger, multispecies aquarium. In the smaller …

Bryce Canyon Aspen: Recent Trends, Future Actions, Paul C. Rogers

Aspen Bibliography

In cooperation with Bryce Canyon National Park, we undertook a survey of quaking aspen (Populus tremuloides Michx.) conditions throughout the Park with the intention of better understanding conditions and prescribing corrective measures where needed. There are clear disparities within the Park between sustainable aspen conditions and failing stands. Based on condition of mature trees, but most importantly regeneration and recruitment of juvenile stems, most aspen forests within Bryce Canyon are in poor condition. Aspen recruitment—generally sapling-sized trees that have survived browsing ungulates—is the most important metric of future stand resilience and here we found 83% of all aspen sample …

Inhibition Of The Metalloprotease Adam19 As A Novel Senomorphic Strategy To Ameliorate Gut Permeability And Senescence Markers By Modulating Senescence-Associated Secretory Phenotype (Sasp)., Sudipta Bar, Tyler A U Hilsabeck, B Pattavina, José Alberto López-Domínguez, Nathan Basisty, Joanna Bons, Mark Watson, Birgit Schilling, Judith Campisi, Pankaj Kapahi, Amit Sharma

Faculty Research 2025

Accumulation of DNA damage can accelerate aging through cellular senescence. Previously, we established a Drosophila model to investigate the effects of radiation-induced DNA damage on the intestine. In this model, we examined irradiation-responsive senescence in the fly intestine. Through an unbiased genome-wide association study (GWAS) utilizing 156 strains from the Drosophila Genetic Reference Panel (DGRP), we identified meltrin (the drosophila orthologue of mammalian ADAM19) as a potential modulator of the senescence-associated secretory phenotype (SASP). Knockdown of meltrin resulted in reduced gut permeability, DNA damage, and expression of the senescence marker β-galactosidase (SA-β-gal) in the fly gut following irradiation. Additionally, inhibition …

Anti-Maa Antibodies Increase Disease Severity In A Mouse Model Of Inflammatory Bowel Disease, William P. Mcguire Iii, Michael J. Duryee, Rizwan Ahmad, Punita Dhawan, Amar B. Singh, Geoffrey M. Thiele

EMET Projects

No abstract provided.

Women's Empowerment In Apcnf: A Critical Examination Of Feminist Goals In Agroecology, Anvitha Ravipati

Student Scholarship

This paper delves into the critical issues surrounding agroecology, with a specific focus on the intersection of ecology, polity, society, and economy. In the context of the Anthropocene era, the global threat of climate change poses significant challenges such as rising sea levels, extreme weather events, and disruptions in food production. The paper highlights the predicted impacts of climate change on food security, particularly in the tropics, emphasizing the need for social and environmental justice in mitigation and adaptation efforts. Furthermore, it discusses the concept of political agroecology as a lens to address sociological and political aspects within the realm …

Michigan Academician, Volume 49, Issue 3

Michigan Academician

Michigan Academician Volume 49, Issue 3

Using The 5ms Framework To Advance Aging-Responsive Care For Heart Failure With Reduced Ejection Fraction, Abigail Latimer, Debra K. Moser, Jia-Rong Wu, Kim K. Birtcher, Malachy J. Clancy, Jennifer D. Portz, Joanna Paladino, Daniel D. Matlock, Christopher E. Knoepke

Department of Occupational Therapy Faculty Papers

Complexity of care is the inevitable consequence of an aging population and is particularly true in instances where patients are managing chronic conditions such as heart failure with reduced ejection fraction (HFrEF). HFrEF itself is complex, with an undulating course of illness, increased risk of sudden cardiac death, and myriad accompanying treatment considerations. Generalist management of HFrEF among older patients is further complicated by competing comorbidities, potential for financial toxicity, potential for mental health symptoms, and risk of care with does not align with goals and preferences. The 5Ms (multicomplexity, mind, mobility, medications, and matters most) is a holistic conceptualization …

Effective Risk Management Strategies Minority Small Business Owners Use To Address Challenges Of Changing Business Environments, Sabit Yasin Mohammed

Walden Dissertations and Doctoral Studies

As a result of a lack of effective risk management strategies, some minority small business owners are unable to address business challenges during changing business environments. Small business leaders who cannot mitigate challenges in changing business environments risk financial loss and business failure. Grounded in general system theory and entrepreneurship theory, the purpose of this qualitative pragmatic inquiry study was to explore effective risk management strategies of minority small business owners used to mitigate challenges of changing business environments. The participants were six minority small business owners from southwest region of the United States who successfully mitigated the challenges of …

Little Island Pond (2022 Water Quality Report), Amanda Mcquaid, Bob Craycraft

UNH Cooperative Extension

No abstract provided.

2024 Llmp Weather Overview, Bob Craycraft, Amanda Mcquaid

UNH Cooperative Extension

No abstract provided.

Merrymeeting River 2024 Water Quality Highlight Report, Bob Craycraft, Miranda Benson, Amanda Mcquaid

UNH Cooperative Extension

No abstract provided.

Art Therapists’ Perspectives On Exploring Sexuality In Treatment Sessions, Daniel Blausey

Expressive Therapies Dissertations

This study examined the relationships between U.S. based graduate-level art therapists’ (N = 174) personal and professional characteristics and their decisions to explore sexuality in sessions. A mixed-methods concurrent design generated quantitative and qualitative data through a one-time anonymous internet study centering on two clinical case vignettes. One vignette highlighted gender nonconformity, the other the sexualization of the therapist. Comparison of years of art therapy experience for two groups, those who interacted with one vignette before exiting and those who interacted with both found the group that rated both vignettes had more years of AT experience (M = …

A Rare Synchronous Existence Of Warthin’S Tumour And Oral Cancer: A Systematic Review, Gargi Sarode, Swapnagandha Mahindre, Vini Anand, Rahul, Namrata Sengupta, Shruti Singh, Sachin Sarode

Sultan Qaboos University Medical Journal

Oral squamous cell carcinoma (OSCC) is a common malignancy, while Warthin's tumour (WT) is a benign salivary gland neoplasm, typically found in the parotid gland but rarely involving extra-parotid tissues. The synchronous occurrence of OSCC and extra-parotid WT is particularly unusual. Accurate identification of these pathologies is crucial, as their rare presentation can resemble metastasis in lymph nodes. This review systematically searched for case reports and series of synchronous WT and OSCC, including 13 papers having 17 cases. The quality of these cases was assessed using CARE guidelines. The findings described WT's histological features and location in patients with OSCC, …

Improving Female Health At Various Life Stages: A Systematic Review Of The Impact Of Date Fruit Products, Elham Shirdel, Farinaz Rahimi, Masoumeh Abdi, Fatemeh, Fatemeh Alsadat Rahnemaei

Sultan Qaboos University Medical Journal

This systematic review examines the effects of date fruit products on female health across different life stages. The quality of the included studies was assessed using the risk of bias tool. A total of 21 eligible studies were reviewed, demonstrating that date fruit consumption benefits puberty, reproductive health, and menopause. During puberty, date fruit intake was associated with improved hemoglobin levels in adolescent girls. In reproductive-age women, date fruits positively influenced fertility parameters and sexual function. Additionally, in menopause, they contributed to alleviating dyspareunia and supporting ovarian reserve maintenance. Providing women with proper nutrition and integrating date fruits into their …

Characteristics And Outcomes Of Cancer Patients Admitted To The Hospital With Community-Acquired Pneumonia, Anoud Al-Saleh, Dana Hassouneh, Sara Faqeer, Nour

Sultan Qaboos University Medical Journal

Objectives: Community-acquired pneumonia (CAP) poses a significant risk of complications in cancer patients. However, limited studies have evaluated hospitalised cancer patients with CAP. This study aimed to evaluate the characteristics and outcomes of cancer patients hospitalised with CAP. Methods: This retrospective study included adult cancer patients diagnosed with CAP admitted at the King Hussein Cancer Center, Jordan, from January 2021 to August 2022, following the Infectious Diseases Society of America guidelines. Patient characteristics, microbiological cultures, length of hospital stay, intensive care unit (ICU) transfers and all-cause mortality were recorded. Early clinical stability was defined as temperature ≤37.8°C, heart …

Vitamin D Status And Oxidative Stress In Children With Sickle Cell Anaemia In Sagamu, Nigeria, Ayobola A. Sonuga, Oyebola O. Sonuga, Olatunbosun O. Ogundeji, Sunday P.

Sultan Qaboos University Medical Journal

Objectives: Sickle cell anaemia (SCA) is characterised by nutritional deficiencies and oxidative stress. Vitamin D possesses antioxidant properties; however, its role in SCA within sub-Saharan Africa remains inadequately understood. This study aimed to investigate the relationship between vitamin D status, oxidative stress and antioxidant levels in children with SCA, exploring its possible role in mitigating complications associated with oxidative stress in SCA. Methods: This study was conducted for a period of 9 months from November 2022 until July 2023 at the Olabisi Onabanjo University Teaching Hospital (OOUTH), Sagamu, Nigeria. This case-control study involved 100 HbS genotype and 100 HbA genotype …

Clinicopathological Spectrum Of Myxoid Soft Tissue Tumours With Emphasis On Diagnostic Differentials, Sanjana Ahuja, Nisha Modi, Amit Kapur, Shivani, Kamal Malukani, Harshita Deep Sahu

Sultan Qaboos University Medical Journal

Objectives: Myxoid soft tissue tumours (MSTTs) represent a complex group of mesenchymal neoplasms characterised by the production of an extracellular myxoid matrix, which often poses diagnostic challenges. This study aimed to identify the relative frequency, distribution and morphological spectrum of MSTT as well as to illustrate commonly encountered diagnostic difficulties. Methods: This retrospective study of the clinicopathological profiles of MSTT cases at Sri Aurobindo Medical College & Post Graduate Institute, Indore, India, was conducted from January 2020 to December 2023. Results: A total of 110 MSTT cases were included in this study. These cases accounted for 7.3% …

Endobronchial Metastasis With Extension To The Left Atrium From Adenocarcinoma Of Gastric 3 Years After Total Gastrectomy, Behnam Shakerian, Mohammad H. Mandegar

Sultan Qaboos University Medical Journal

Endobronchial metastases extending to the heart from gastric cancer are rare. This case report describes a 69-year-old man who presented to a tertiary care hospital in Shahrekord, Iran, in 2022 with a history of cough and haemoptysis. He had previously undergone total gastrectomy and adjuvant chemotherapy for gastric adenocarcinoma three years earlier. Imaging and pathological evaluation confirmed endobronchial metastasis with extension to the left atrium. The patient responded well to chemoradiotherapy, maintaining a good quality of life.

Deciphering The Dark Cancer Phosphoproteome Using Machine-Learned Co-Regulation Of Phosphosites, Wen Jiang, Eric J Jaehnig, Yuxing Liao, Zhiao Shi, Tomer M Yaron-Barir, Jared L Johnson, Lewis C Cantley, Bing Zhang

Faculty, Staff and Students Publications

Mass spectrometry-based phosphoproteomics offers a comprehensive view of protein phosphorylation, yet our limited knowledge about the regulation and function of most phosphosites hampers the extraction of meaningful biological insights. To address this challenge, we integrate machine learning with phosphoproteomic data from 1195 tumor specimens spanning 11 cancer types to construct CoPheeMap, a network that maps the co-regulation of 26,280 phosphosites. By incorporating network features from CoPheeMap into a second machine learning model, namely CoPheeKSA, we achieve superior performance in predicting kinase-substrate associations. CoPheeKSA uncovers 24,015 associations between 9399 phosphosites and 104 serine/threonine kinases, shedding light on many unannotated phosphosites and …

Nutritional Status, Social Determinants Of Health And Clinical Outcomes In Critically Ill Children, Yash Desai, Andrea Marroquín, Paola Hong-Zhu, Nicole Knebusch, Stephanie Vazquez, Marwa Mansour, Thomas P Fogarty, M Hossein Tcharmtchi, Fernando Stein, Jorge A Coss-Bu

Faculty, Staff and Students Publications

Introduction: Childhood malnutrition remains a risk factor for morbidity and mortality. Children admitted to the Pediatric Intensive Care Unit (PICU) are at a higher risk of worsening nutritional status with adverse clinical outcomes. The burden of malnutrition is strongly linked to various well-defined social determinants of health, including race, socioeconomic status, and geography, as these factors influence household food insecurity. This study aimed to analyze the interrelationships of nutritional status, social determinants of health, and health outcomes in critically ill children.

Methods: Retrospective cohort study of 6418 critically ill children admitted to PICU from January 2014 to December 2017. Demographic …

Attitudes And Barriers Toward Antiretroviral Therapeutic Drug Monitoring Among Infectious Disease Providers, Hongmei Wang, Cecilia M Torres, Thomas P Giordano, Bich N Dang, Dong Liang

Faculty, Staff and Students Publications

Background/Objectives: Effective HIV treatment and prevention rely heavily on patient adherence to the prescribed regimen. Therapeutic drug monitoring (TDM), which involves measuring medication concentrations in blood circulation, offers an objective method to evaluate toxic or ineffective drug levels. TDM is not routinely used in HIV treatment in clinical practice. Therefore, the purpose of this study is to survey infectious disease providers’ attitudes and barriers toward therapeutic drug monitoring for antiretroviral therapy in people living with HIV. Materials and

Methods: A 15-item online survey was distributed to infectious disease providers in the Greater Houston area, including physicians, pharmacists, and mid-level practitioners …

Michigan Academician, Volume 49, Issue 2

Michigan Academician

Michigan Academician Volume 49, Issue 2.

Adipose Progenitor Cell-Derived Extracellular Vesicles Suppress Macrophage M1 Program To Alleviate Midlife Obesity, Qing Zhou, Jia Gao, Guorao Wu, Chenwei Wang, Yan Yang, Teng Huang, Yi Wang, Tiantian Yue, Zhichao Gao, Hao Xie, Fei Xiong, Ke Xiang, Tuying Yong, Wanguang Zhang, Tongtong Zhang, Wen Kong, Cai Chen, Shu Zhang, Qilin Yu, Xuemei Fan, Shiwei Liu, Yanjun Liu, Cong-Yi Wang

Children’s Nutrition Research Center Staff Publications

Among different age groups, middle-aged individuals are particularly susceptible to obesity, with a 22% higher risk of all-cause mortality. However, the underlying mechanisms remain unclear. In this study, we identify adipose progenitor cells (APCs) in the white adipose tissue (WAT) of middle-aged subjects as potential causes of midlife obesity. Specifically, the extracellular vesicles (EVs) derived from APCs display an impaired ability to mitigate the inflammaging of adipose tissue macrophages (ATMs) in middle-aged individuals. Mechanistically, these EVs, lacking miR-145-5p, fail to suppress the expression of L-selectin in ATMs, thereby facilitating their M1 program via the NF-κB signaling pathway. In contrast, EVs …

Prevalence And Determinants Of Preterm Birth Among Women Of Reproductive Age In Kenya: A Multilevel Analysis Of The 2022 Demographic Health Survey, Kobi V. Ajayi, Obasanjo Bolarinwa, Toluwani E. Adekunle, Oluwatobi Abel Alawode, Nanyangwe Siuluta, Sinegugu Shongwe, Edyta Mccallum

University Faculty Publications and Creative Works

Preterm birth (PTB) is when a baby is born before 37 weeks of pregnancy. It’s a major public health issue, with over 15 million cases globally each year. Sub-Saharan Africa, including Kenya, has a high share of PTB, but there’s limited research about it in Kenya. This study looked at how common PTB is in Kenya and what factors increase the risk. Using data from the 2022 Kenya Demographic and Health Survey, the authors analysed 7,291 women aged 15–49. They used statistical methods to find patterns and identify factors linked to PTB. The study found that 7.14% of women in …

Herbivory In A Low Arctic Wetland Alters Intraspecific Plant Root Traits With Consequences For Carbon And Nitrogen Cycling, Emily A. Chavez, Jaron Adkins, Bonnie G. Waring, Karen H. Beard, Ryan T. Choi, Lindsay Miller, Taylor Saunders, Trisha B. Atwood

Wildland Resources Faculty Publications

1. High latitude wetlands are ecologically important ecosystems due to their large carbon (C) storage capacity and because they serve as breeding and nesting habitat for large populations of migratory birds. Goose herbivory in wetland meadows affects leaf chemical and morphological traits and also influences soil properties by increasing soil temperature and depositing faeces. Grazing-induced changes to above-ground traits and soil properties impact C cycling, but the influence of grazing on root-mediated C and nitrogen (N) cycling has not been explored.

2. We investigated how goose herbivory in a low-Arctic coastal wetland in western Alaska affected root morphological, physiological and chemical traits …

Bridging Sky And Sea: Joint Strategies For Medical Evacuation In The Indo-Pacific, Mahdi Al-Husseini, Samuel J. Diehl, Samuel L. Fricks

The US Army War College Quarterly: Parameters

This article contends that the US Army should coordinate agile and expeditious Joint medical evacuation operations in the Indo-Pacific and develop novel capabilities to do so effectively. There has been limited discussion among scholars and practitioners on modern maritime medical evacuation tactics and techniques inspired by history and informed by contemporary threats. This article introduces three new medical evacuation capabilities and makes six recommendations to advance a Joint maritime medical evacuation operating concept. It provides a framework for medical planners developing evacuation systems in maritime theaters and justifies how and why the US Army should play a substantial role in …

Desired Student Learning Outcomes For Middle School Agricultural Education: A Modified Delphi Study, Jacob P. Englin

LSU Doctoral Dissertations

Middle school agricultural education programs across the U.S. have continued to increase, but modern systems have failed to provide support for the preparation of middle school agricultural education teachers. For instance, middle school teachers have expressed concern regarding the development and implementation of middle school agricultural curriculum. In response, this investigation sought to identify learning outcomes related to agricultural content, technical skills, and career readiness for middle school agricultural education. A modified, three-round modified Delphi study was used to identify these learning outcomes. The expert panelists consisted of 19 middle school agricultural education teachers who completed a teacher certification program …

Variation In Response To Phosphorus Among Sweetpotato (Ipomoea Batatas L.) Cultivars, Jeffrey Cole Denis Gregorie

LSU Doctoral Dissertations

Phosphorus (P) is essential for plant growth and is often a major limiting nutrient in agriculture. In sweetpotato (Ipomoea batatas), studies on the role of P on storage root yield have been limited because of the lack of response and inconsistent results across cultivars and years. Growing evidence shows that current phosphate (Pi) fertilizer rates can be reduced while maintaining productivity. Newly published molecular evidence shows differential expression of phosphate starvation response genes among sweetpotato cultivars, further supporting the hypothesis of cultivar-specific Pi sensitivity. The research herein sought to characterize root system architecture and yield response to Pi …