Digital Commons Network^™

Specialty Grand Challenge: Existing Issues And Emerging Frontiers In Renal Endocrinology, A. T. M. Emdadul Haque, Mohammed S. Razzaque

School of Medicine Publications

We are currently in an exciting time to advance the field of renal endocrinology. There has never been a more favorable time to study the molecular and cellular mechanisms underlying renal hormone functions in physiology, pharmacology, and pathophysiology. The availability of advanced research tools provides unique opportunities to dissect the complex regulatory roles of renal hormones. The kidneys are vital organs in the human body; each one is composed of approximately one million functional nephrons. Understanding the precise roles and regulation of kidney-derived hormones and hormones that exert endocrine effects on the kidneys will help in preventing or delaying various …

Low Heat Flow In The Anhydros Basin, Aegean Sea, Recorded By Deep Subsurface Temperatures, Michael Manga, Masako Tominaga, Jonas Preine, Thomas A. Ronge, Sarah Beethe, Christian Hübscher, Iona Mcintosh, Paraskevi Nomikou, Steffen Kutterolf, Tim Druitt, Alexis Bernard, Carole Berthod, Hehe Chen, Acacia Clark, Susan Debari, Tatiana I. Fernandez-Perez, Ralf Gertisser, Raymond M. Johnston, Christopher K. Jones, K. Batuk Joshi, Günther Kletetschka, Olga Koukousioura, Molly Mccanta, Antony Morris, Katharina Pank, Ally Peccia, Paraskevi N. Polymenakou, Adam Woodhouse, Yuzuru Yamamoto

School of Geography, Earth and Environmental Sciences

Subseafloor in situ temperatures in a drilled hole in the Anhydros Basin, Aegean Sea, measured during International Ocean Discovery Program (IODP) Expedition 398, yielded a low heat flow (<0.023 W/m²) despite active magmatism and rifting in the region. The coldest and highest temperatures were 13.9°C at 52.5 m below seafloor (mbsf) and 15.5°C for the deepest measurement at 360.4 mbsf, respectively. Comparison of a heat transfer model with measurements suggests that sea bottom temperatures during the last glacial period were up to 10°C cooler than Holocene temperatures. The magnitude of Holocene warming co-varies with the geothermal heat flow: if …

Spectrophotometric Determination Of Bromhexine-Hcl By Using Prepared Silver Nanoparticles, Zainab Noori, Muna M. Khudhair

Baghdad Science Journal

In this study, a new, simple, and rapid method was developed for determining Bromhexine-HCl using silver nanoparticles. The solution of silver nanoparticles has a yellow color which has absorbency at a wavelength of 404 nm. Bromhexine was estimated through its reaction with silver nanoparticles in acidic environment at pH 5. This reaction causes the silver nanoparticles to aggregate and change the color of their colloidal solution from yellow to brown, leading to a decrease in their absorbance. The range of linearity was found to be 20-250μg mL-1, a limit of detection is equal to 18.931μg/mL and limit of quantitation is …

Cryo-Em Structures Of A Pentameric Ligand-Gated Ion Channel In Liposomes, Vikram Dalal, Brandon K Tan, Hanrui Xu, Wayland W L Cheng

2020-Current year OA Pubs

Detergents and lipid nanodiscs affect the cryo-EM structures of pentameric ligand-gated ion channels (pLGICs) including ELIC. To determine the structure of a pLGIC in a membrane environment that supports ion channel function, we performed single particle cryo-EM of ELIC in liposomes. ELIC activation and desensitization were confirmed in liposomes with a stopped-flow thallium flux assay. Using WT ELIC and a non-desensitizing mutant (ELIC5), we captured resting, activated, and desensitized structures at high resolution. In the desensitized structure, the ion conduction pore has a constriction at the 9' leucine of the pore-lining M2 helix, indicating that 9' is the desensitization gate …

Identification Of Functional Non-Coding Variants Associated With Orofacial Cleft, Priyanka Kumari, Ryan Z Friedman, Michael A White, Barak A Cohen, Et Al.

2020-Current year OA Pubs

Oral facial cleft (OFC) comprises cleft lip with or without cleft palate (CL/P) or cleft palate only. Genome wide association studies (GWAS) of isolated OFC have identified common single nucleotide polymorphisms (SNPs) in many genomic loci where the presumed effector gene (for example, IRF6 in the 1q32 locus) is expressed in embryonic oral epithelium. To identify candidates for functional SNPs at eight such loci we conduct a massively parallel reporter assay in a fetal oral epithelial cell line, revealing SNPs with allele-specific effects on enhancer activity. We filter these SNPs against chromatin-mark evidence of enhancers and test a subset in …

Aeroponic System Optimization For Butterhead Lettuce Growth And Future Sustainability Using Flow Blurring Atomization: An Overview, Taylor J. Johnson

Beyond: Undergraduate Research Journal

The global population has grown by 6 billion people over the last century and is trending toward 9.7 billion people by the year 2050. Agriculture accounts for 70% of global fresh water usage. Technology must be developed to accommodate the increase of food production demanded by the growing global population and the subsequent increase in water usage. Aeroponic technology is a water-efficient vertical farming technology that can reduce water usage by 90% by suspending plant roots in air within a controlled chamber and supplying atomized droplets of a water-nutrient solution directly to the roots.

This study simultaneously tests six droplet …

Seoul’S Soul: A Study Of Drag Culture’S Influence On Queer Young Adult’S Education In South Korea, Ian Sollender

Capstone Collection

Drag performance has long been considered a site of artistic expression, political resistance, and community-building within LGBTQ+ spaces. This capstone research project explores the educational impact of drag culture in Seoul, South Korea, with a particular focus on how drag performances serve as a pedagogical and educational tool that challenges gender norms, fosters queer community, and provides a platform for political discourse. Through qualitative analysis of participant observation, bilingual Korean and English survey responses, and in-depth English interviews with drag performers, performance organizers, and audience members, this research highlights the ways in which drag can function as a site of …

Flow-Nalytics: A Monitoring, Evaluation And Learning Capacity Assessment Of A Menstrual Health Education Organization, Chanel Jimenez

Capstone Collection

This capstone project explored the monitoring, evaluation and learning (MEL) capacities of an organization in Colombia that promotes comprehensive menstrual education. The current contexts surrounding menstrual health and hygiene management (MHHM) globally and in Colombia, the relevant policy environment and the MEL context of MHHM were featured prominently in the literature review. Concepts such as feminist pedagogy theory and the term “empowerment” were also explored.

The project methodology consisted of a desk review, facilitated discussions and observed workshops with the organization founder, which used the pseudonym, Tenara. In collaboration with the organization’s founder, the author identified various findings, challenges and …

Examining Weight Bias Attitude Changes After Exposure To A Brief Photovoice Assignment, Gretchen L. George, Hillary L. Roberts, Kristin Rose, Madison Clemens, Kate G. Burt

Journal of Dietetic Education

Weight bias is present among pre-health professional students (e.g., nutrition, dietetics, nursing, physical therapy, medicine). Educators need support and guidelines about how to enhance learning through engaging assignments while also meeting accreditation requirements. This pilot study examined the impact of an innovative weight bias assignment using photovoice and reflection within existing nutrition education courses, measured through pre-post assessments from the Fat Attitudes Assessment Toolkit. While not all subscales showed significant change, improvements in the Fat Acceptance and Attribution Complexity Composites suggest these methods may be effective in shifting attitudes about fatness. Further research is needed to assess the long-term impact …

Integrated Advanced Education Supports Future Registered Dietitian Nutritionists’ Breastfeeding Self-Efficacy In Practice, Crystal C. Douglas, Simone Camel

Journal of Dietetic Education

Objective: Evaluate the effectiveness of graduate-level breastfeeding and lactation management education that includes didactive and active learning components on future RDNs’ knowledge, attitudes, and self-efficacy. Design: A pre-and post-test design, utilizing a 41-item pre-intervention survey, learning modules, and a 35-item post-intervention survey. Setting: Three U.S. public universities located in Texas, Louisiana, and Arkansas. Participants: Graduate-level dietetic internship students. Intervention: Four advanced education modules (2 didactive; 2 active learning) developed by Registered Dietitian Nutritionists. Main outcome measures: Gains in breastfeeding knowledge, attitudes, and self-efficacy to assist with breastfeeding education and problem-solving using validated and newly developed survey items. Analysis: Descriptive statistics, …

Sense Of Belonging In The Profession And Program Of Study Among Nutrition And Dietetics Students, Jessica Torro, Melissa Masters, Rachel C. Sinley, Jesse Lunsford, Heidi Masching, Miranda Chen Musgrove

Journal of Dietetic Education

Sense of belonging may positively impact student performance, especially in marginalized groups. This study aimed to examine sense of belonging among a diverse group of nutrition and dietetics students. An online survey investigated students’ feelings of belonging, isolation, and connection to the field of nutrition and dietetics and department of study. The survey was distributed through email to the nutrition and dietetics student body in the Department of Nutrition at Metropolitan State University of Denver. Quantitative data were analyzed as count and percentage. Overall sense of belonging scores were calculated as an average on a 5-point scale (1-strongly disagree to …

Reviews: The Quickening: Antarctica, Motherhood, And Cultivating Hope In A Warming World, Rachel T. Buxton, Eric J. Woehler

Marine Ornithology

No abstract provided.