Digital Commons Network^™

Delusion Or Faith? Exploring Religious Delusions In Individuals With Schizophrenia Within The Banjar Culture, Nabila Regita Putri Mustafa, Nur’Aulia Maisyarah, Aulia Maulidina, Muhammad Reza Aditya, Muhammad Abdan Shadiqi

Makara Human Behavior Studies in Asia

Schizophrenia is often characterized by delusions and hallucinations, which often appear as manifestations of religious delusions in the Banjar cultural context. This phenomenon can be understood through the hyper-religiosity theory, which explains excessive religious behavior in individuals with schizophrenia. This qualitative case study aims to identify the forms of religious delusion in individuals with hyper-religiosity and the underlying causal factors. Data were collected through in-depth interviews and observations with 10 informants, comprising four individuals with religious delusions selected using purposive sampling based on their experience of studying Tasawwuf and experiencing religious delusions and six significant others. The findings show that …

Road To Recovery: Understanding The Personality Typology, Clinical Features, And Risk Of Relapse In Filipinos With Substance Use Problems, Marc Angelo Ronquillo, Marc Eric Reyes, Ryan Francis Cayubit

Makara Human Behavior Studies in Asia

Knowing the patient’s personality can assist the clinician in improving their relationship and tailoring the interventions for the patient. Several studies have reported that treatment and prevention programs must be tailored to an individual’s social and cultural attributes to facilitate continuous recovery and prevent relapse. This study aimed to develop a deeper understanding of the personality typology, clinical features, and risk of relapse in Filipinos with substance use problems in rehabilitation centers. We used a sequential-explanatory mixed-method approach with two phases (Phase 1: descriptive, cross-sectional design; Phase 2: phenomenological design) to provide an evidence-based framework to tailor treatment according to …

Dietary Lipids Induce Ppard And Bcl6 To Repress Macrophage Il-23 Induction After Intestinal Injury And Lps Exposure, Ashleigh M Gil, Daniel F Zegarra-Ruiz, Wan-Jung Wu, Kendra Norwood, Adrien Assie, Buck S Samuel, Angela M Major, Gretchen E Diehl, Andrea A Hill Mcalester

Faculty, Staff and Students Publications

Unresolved tissue damage is a common feature of Inflammatory Bowel Disease (IBD) that facilitates disease progression. Here, we showed that high animal fat diets (HFD), an environmental risk factor associated with IBD pathogenesis, suppress intestinal macrophage production of critical tissue repair responses after damage. This includes reduced IL-23 production, which drives downstream production of IL-22, which is needed for barrier repair. Indicating that dietary lipids interfere with responses to microbial molecules needed to induce barrier protective functions, we found oleic acid could directly suppress macrophage Il23a induction after lipopolysaccharide (LPS) treatment. Deleting the lipid transporter CD36 on macrophages restored the …

Combination Of Irreversible Electroporation And Clostridium Novyi-Nt Bacterial Therapy For Colorectal Liver Metastasis, Zigeng Zhang, Guangbo Yu, Qiaoming Hou, Farideh Amirrad, Sha Webster, Surya M. Nauli, Jianhua Yu, Vahid Yaghmai, Aydin Eresen, Zhuoli Zhang

Pharmacy Faculty Articles and Research

Colorectal liver metastasis (CRLM) poses a significant challenge in oncology due to its high incidence and poor prognosis in unresectable cases. Current treatments, including surgical resection, systemic chemotherapy, and liver-directed therapies, often fail to effectively target hypoxic tumor regions, which are inherently more resistant to these interventions. This review examines the potential of a novel therapeutic strategy combining irreversible electroporation (IRE) ablation and Clostridium novyi-nontoxic (C. novyi-NT) bacterial therapy. IRE is a non-thermal tumor ablation technique that uses high-voltage electric pulses to create permanent nanopores in cell membranes, leading to cell death while preserving surrounding structures, and …

Demystifying The Nuances Of The Lipid Patient: A Guide For Primary Care Providers, Merle Myerson, Kyle Gillett, James O'Hara, Richard Potter, Neil Skolnik

Abington Jefferson Health Papers

Atherosclerosis, a major cause of mortality and morbidity in the United States (US), is driven by complex factors, including the cumulative burden of low-density lipoprotein cholesterol (LDL-C) and other atherogenic lipids and lipoproteins. Lipid management in US primary care aims to prevent atherosclerotic cardiovascular disease (ASCVD) events through screening and LDL-C lowering to risk-based goals. However, lipid screening and ASCVD treatment is often inadequate, with few patients meeting LDL-C goals in clinical practice. Primary care providers have a vital role in identifying patients most at risk of ASCVD to prevent ASCVD events and improve patient outcomes. There are multiple different …

Transformation With Genes To Improve Lipid Production And Barcoding To Identify Unknown Algal Species, Michelle T. Rada

Theses and Dissertations

With the rising demand for alternative fuels, algal-based biofuels are a promising, sustainable source that meets commercial interest while producing lower greenhouse gas emissions compared to fossil fuels. This thesis explored two studies, evaluating microalgae for their future potential in lipid yield for biofuel production.

The first study involved developing a cost-efficient electroporation protocol that allowed for the genetic transformation of Chlamydomonas reinhardtii using the pChlamy_4 vector, which supports future cloning of genes to enhance lipid production. Parameters affecting DNA uptake and integration into algal genomes were studied: the effect of cell density, the settings of the electroporation device, and …

Targeting Poor Solubility Of Docetaxel: Computational Screening Of Ionic Liquids Using Cosmo-Rs, Najihah Mohd Noor, Amal A.M. Elgharbawy, Huma Warsi Khan, Yumi Zuhanis Has-Yun Hashim, Muhammad Moniruzzaman, Mohd Firdaus Abd. Wahab, Hamzah Mohd Salleh, Siti Nur Idayu Matusin

Publications and Research

Docetaxel (DTX), a chemotherapeutic agent widely used in cancer treatment, has limited therapeutic efficacy owing to its poor oral absorption and low bioavailability. This study aims to improve DTX solubility by predicting its compatibility with ionic liquids (ILs) using conductor-like screening model for real solvents (COSMO-RS) computational modelling. A library of 340 ILs comprising 17 cations and 20 anions was screened for their potential to dissolve DTX, with a particular focus on imidazolium-based ILs that enhance its solubility and pertinence to cytotoxic applications. Computational analysis identifies ILs containing cations such as 1-methylimidazolium [MIM] and 1,3-dimethylimidazolium [DMIM] and anions such as …

Rna Sequencing Reveals Inflammatory And Metabolic Changes In The Lung And Brain After Carbon Black And Naphthalene Whole Body Inhalation Exposure In A Rodent Model Of Military Burn Pit Exposures, Allison M. Haaning, Brian J. Sandri, Henry L. Wyneken, William T. Goldsmith, Joshua P. Nixon, Timothy R. Nurkiewicz, Chris H. Wendt, Paul Barach, Janeen H. Trembley, Tammy A. Butterick

College of Population Health Faculty Papers

Military personnel deployed to Iraq and Afghanistan were exposed to emissions from open-air burn pits, where plastics, metals, and medical waste were incinerated. These exposures have been linked to deployment-related respiratory diseases (DRRD) and may also impact neurological health via the lung-brain axis. To investigate molecular mechanisms, adult male rats were exposed to filtered air, naphthalene (a representative volatile organic compound), or a combination of naphthalene and carbon black (surrogate for particulate matter; CBN) via whole-body inhalation (six hours/day, three consecutive days). Lung, brain, and plasma samples were collected 24 h after the final exposure. Pro-inflammatory biomarkers were assessed using …

Cora Greene

African American Funeral Programs

Cora_Greene.pdf - Funeral program for Cora Greene

Single-Cell Transcriptomics Of Ventral Forebrain Progenitors Identifies Evf2 Enhancer Lncrna-Enhancer Gene Guidance Through Direct Rna Binding And Rnp Recruitment Domains, Edward Li, Abhijit Chakraborty, Sara J Kohtz, Ivelisse Cajigas, Laura Hinojosa-Gonzalez, Fion Shiau, Ryan Bertossi, Robert J Vassar, Jack A Kessler, Ferhat Ay, Brian S Clark, Jhumku D Kohtz

2020-Current year OA Pubs

During mouse embryonic brain development, the Evf2 ultraconserved enhancer (UCE) lncRNA guides the Dlx5/6UCE to ~129 sites across chr6. However, previous work identified only 4 transcriptionally regulated targets associated with Evf2-Dlx5/6UCE-gene guidance, raising questions about the significance of Evf2-regulated Dlx5/6UCE-gene interactions. Here, single-cell transcriptomics reveal far greater alignment between Evf2-Dlx5/6UCE-gene guidance and transcriptional regulation than previously reported. Evf2 divides chr6 into short-range ( < 10 Mb distant), activated genes, and long/super-long-range (10-129 Mb distant), repressed genes, identifying seizure regulating genes in the embryonic subventricular zone that predict adult phenotypes. Evf2-regulated Dlx5/6UCE-gene distances and directions (closer to or further from gene targets) can be decoupled from gene target transcriptional effects. Evf2 regulates Evf2-ribonucleoprotein (RNP) binding in a combinatorial manner to key regulatory sites, including chr6 Evf2-Dlx5/6UCE-gene guided sites, Evf1/2 RNA-directly bound sites (RBSs), and inter-chromosomal HiC looping interactions. RBSs divide chromosomes into multi-megabase domains enriched for Evf2-regulated RNP recruitment, transcription factor motifs, and HiC looping interactions. Together with Evf2-controlled homeobox motif recognition at Evf2-RNP recruitment sites and transcription factor motif enrichment in RBSs with DNA identity, this work supports direct roles for Evf2 in enhancer-gene guidance and transcriptional regulation, with the potential for both site-specific and chromosomal domain specific RNP recruitment.

A Rare Case Of Rapidly Progressing Merkel Cell Carcinoma, David Sau Ting Jain, Omer Riyadh, Kayla Tran, Nguyen L. Ngo, Dei-Wook Kang

Student Publications

Merkel cell carcinoma (MCC) is a highly aggressive neuroendocrine tumor, known for its rapid progression and poor prognosis. It most commonly affects elderly and immunocompromised individuals, with variable clinical presentations that can make diagnosis challenging. MCC is often mistaken for other skin malignancies, such as basal or squamous cell carcinoma, or even benign skin lesions. Early diagnosis is critical to initiate appropriate treatment, typically involving surgery, radiation, and immunotherapy. This report describes a 66-year-old man diagnosed with MCC with regional lymph node involvement. Immunotherapy was started promptly; however, within a year, the disease progressed to the mediastinum, involving the esophagus …

Flow Dynamics And Local Scour Around Seabed-Mounted Artificial Reefs: A Case Study From Torbay, Uk, Yeaw Chu Lee, Amir Bordbar, Jakub Knir, Vasilios Kelefouras, Stephen Hickling, Harrison Short

School of Engineering, Computing and Mathematics

This study investigates the flow dynamics and local scour around a Reef Cube® artificial reef deployed in Torbay, UK, using computational fluid dynamics. The flow is modelled using Reynolds-Averaged Navier–Stokes (RANS) equations with a k-ω SST turbulence model. A novel hydro-morphodynamic model employing the generalized internal boundary method in HELYX (OpenFOAM-based) is used to simulate scour development. Model performance was validated against experimental data for flow fields, bed shear stress, and local scour. Flow simulations across various scenarios demonstrated that parameters such as the orientation angle and arrangement of Reef Cubes significantly influence flow patterns, bed shear stress, and habitat …

Glimmer Gathering: Healing And Reciprocity, Maria Rios

POC in LIS Summit

Glimmer gathering is a trauma-informed list making practice; an excavation and unearthing of what already exists inside of you. As library and information science professionals--we, especially Black, Indigenous, POC women-- are tasked with being the expert, exceptional, and overextended---and ultimately led to burn out. Capitalism relies on us being disconnected from our bodies so that we remain pliable to extractive, depleting, and harmful cycles. Rather than giving you a prescriptive list of "what to do" to heal and break these cycles; I will offer a few suggestions and invite us to co-create a shared body of creative knowledge. Gather for …

Adolescent Intermittent Alcohol Exposure Alters Pain Related Behaviors And Anxietylike Responses In Mice, Grace Fleshman

Summer Research Internship Program

No abstract provided.

Differentially Expressed Mirnas Linking Transportation Infrastructure To Tnbc Stages At Diagnosisdifferentially Expressed Mirnas Linking Transportation Infrastructure To Tnbc Stages At Diagnosis, Nathan Xiang

Summer Research Internship Program

No abstract provided.

Requirement Of Endothelial Ovol1-Slug For Tumor Angiogenesis In Colorectal Cancer, Shawn Sutherland

Summer Research Internship Program

No abstract provided.

Rnai Knockdown Screen Reveals Genes Required For Non-Professional Phagocytosis In Drosophila Melanogaster, Elinor Romaguera

Summer Research Internship Program

No abstract provided.

In Vitro Comparison Of Oral Squamous Cell Carcinoma Hpv-Positive And Hpv-Negative Invasiveness And Voltage-Gated Sodium Channel Isoforms Expression, Alexis Gray

Summer Research Internship Program

No abstract provided.

Interferon-Gamma Expression Increases In Senescent Immune Cells Following Stimulation Of Peripheral Blood Mononuclear Cells, Aditi Shridhar

Summer Research Internship Program

No abstract provided.

Abstract Book (Pdf), School Of Medicine

Summer Research Internship Program

Abstract Book for the 2025 Summer Research Internship Program. Participants are listed alphabetically by last name.

Full Issue - Spring 2023 - Volume 110, Issue 1, Colby College

Colby Magazine

Spring 2023, vol. 110 no. 1

04: From the Editor
05: Table of Contents
06. Downtown Colby
14. Diagnosing Autism More Precisely
16. An Inside Pitch
22. Colby's New Labs Address Critical Issues and Initiatives
26. In Support of the Academic Mission
28. A Building for Everybody
36. Robust Financial Aid Program is Key to Colby's Mission
38. 'Quite a Triumph'
44. Class Notes
66. Obituaries
80. William R. Cotter, Colby's Longest-Tenured President

Reframing Sleep Diagnostics: A Structured Clinical Guide To Polysomnography Evaluation, Elvie Zulka Kautzia Rachmawati, Mikhael Yosia

AUIQ Complementary Biological System

Polysomnography (PSG) remains the gold standard for evaluating sleep-disordered breathing (SDB) and related conditions, yet its clinical potential is often limited by overreliance on the apnea-hypopnea index (AHI) and similar summary metrics. This narrative review offers a structured, physiology-informed approach to PSG interpretation that integrates sleep architecture, arousal burden, respiratory event morphology, oxygenation patterns, and CO₂ trends. Recognizing phenotypic patterns-such as REM-related and positional OSA-through sleep stage and positional stratification is essential for directing targeted therapy. We outline common interpretive pitfalls, including automated scoring errors, overlooked signal artifacts, and the first night effect, emphasizing the need for careful manual …

Transformative Role Of Laser Technology In Ophthalmology And Dermatology: A Mini Review Of Precision Applications In Modern Medicine, Haider Hameed, Maryam Aqeel, Hussein Rafid, Rasha Sabah, Mustafa Fadhel, Zahraa Hameed, Muqtada Khalawi, Zahraa Sarmed, Ail Ahmed, Ayat Abd Albari, Lina M. Shaker

AUIQ Complementary Biological System

Laser technology has significantly transformed healthcare and biological sciences by Laser devices are offered precision, efficiency, and Multiple simple solutions in various medical fields and research domains. In ophthalmology, lasers play a pivotal role in vision correction, retinal imaging, and therapeutic applications, such as femtosecond laser-assisted LASIK and two-photon fluorescence scanning laser ophthalmoscopy. Dermatology has also benefited from CO₂, Nd:YAG, excimer, and Q-switched lasers, which are widely used for pigmentation disorders, tattoo removal, and skin rejuvenation. Moreover, Low-Level Laser Therapy (LLLT) enhances wound healing and tissue regeneration, while intense pulsed light (IPL) and diode lasers improve hair removal …

Detection Of Oil Pollution On The Tigris River In Iraq Using Fluorescence And Reflecting Techniques, Ahmad K. Ahmad, Thamer M. Mohammed

Karbala International Journal of Modern Science

In this study, a broadband light source (visible and ultraviolet) was used to name minerals via fluorescence spectra and estimate slick oil thickness, ranging from sub-millimetres, using the reflecting spectrum technique. Using a fluorescent technique, we obtained fluorescence spectra of the samples, converting and processing the signals to produce high-resolution data, which enabled the identification of the types of dissolved elements and oil slicks in the Tigris River, highlighting pollution sources and potential control measures. This system aims to show the faint signal in fluorescence samples collected from the cooling system outlet water throughout the refining process from AL-Dora (Baghdad) …

A New Species Of Viscachataenia (Cestoda: Anoplocephalidae) From The Southern Mountain Viscacha, Lagidium Viscacia (Hystricomorpha: Chinchillidae), In Bolivia, Terry R. Haverkost, Scott L. Gardner

MANTER: Journal of Parasite Biodiversity

Anoplocephalid cestodes collected from the southern mountain viscacha, Lagidium viscacia, in Boliva in 1986 are here examined, and a new species of Viscachataenia is described. The new species has numerous body measurements that are larger than the existing species, V. quadrata, but the eggs and corresponding structures of the new species are all smaller than those of V. quadrata.

July 25, 2025 Ereporter, University Of Alabama At Birmingham

eReporter (campus newsletter)

No abstract provided.

Autism Spectrum Disorder: A Review Of Genomic Risk Factors, Diagnostic And Pharmacotherapeutic Strategies, Zohor Azher

Saudi Toxicology Journal

Autism Spectrum Disorder (ASD) is a multifactorial neurodevelopmental condition characterized by impairments in social communication and delayed language development, repetitive behaviors, and sensory processing abnormalities. The genetic background of ASD remains incompletely understood due to significant genetic heterogeneity and complexity. This review aims to present current insights into the genetic landscape of ASD, focusing on both common and rare genomic variations. We describe candidate genes associated with ASD, as they are involved in synaptic function and neuronal signaling, making these findings potential therapeutic targets. This review emphasizes the importance of integrating comprehensive clinical assessments with advanced genetic investigations to enhance …

Epigenetic Profiling Of Cell-Free Dna In Cerebrospinal Fluid: A Novel Biomarker Approach For Metabolic Brain Diseases, Kyle Sporn, Rahul Kumar, Kiran Marla, Puja Ravi, Swapna Vaja, Phani Paladugu, Nasif Zaman, Alireza Tavakkoli

SKMC Student Presentations and Publications

Due to their clinical heterogeneity, nonspecific symptoms, and the limitations of existing biomarkers and imaging modalities, metabolic brain diseases (MBDs), such as mitochondrial encephalopathies, lysosomal storage disorders, and glucose metabolism syndromes, pose significant diagnostic challenges. This review examines the growing potential of cell-free DNA (cfDNA) derived from cerebrospinal fluid (CSF) epigenetic profiling as a dynamic, cell-type-specific, minimally invasive biomarker approach for MBD diagnosis and monitoring. We review important technological platforms and their use in identifying CNS-specific DNA methylation patterns indicative of neuronal injury, neuroinflammation, and metabolic reprogramming, including cfMeDIP-seq, enzymatic methyl sequencing (EM-seq), and targeted bisulfite sequencing. By synthesizing current …

Cognitive Representation And Its Relationship With The Performance Of The Side Kick And Back Kick Skills Among Taekwondo Juniors Aged 12–14 Years, Hind Basim Eidan, Intisar Awaid Ali

Modern Sport

Taekwondo is considered one of the athletic activities that contribute significantly to the holistic development of the individual by fostering the acquisition of knowledge and experience. Contrary to the common misconception that it is merely a form of combat or physical confrontation; taekwondo involves movements that engage both physical and mental activity. This interplay supports the balanced and comprehensive development of the practitioner, thereby enhancing individual efficiency and performance. The aim of the present study was to investigate the relationship between cognitive representation and the performance of the side kick and back kick skills among junior taekwondo athletes aged 12 …

The Impact Of An Ai-Supported Smart Hiit Program On Cardiovascular Fitness And Physical Performance, Maysaa Redha Ghanem

Modern Sport

In recent years, there has been growing interest in training programs that enhance physical fitness and overall health. Among the most prominent is High-Intensity Interval Training (HIIT), which has demonstrated effectiveness in improving cardiovascular efficiency and boosting physical performance within a relatively short period. With rapid advancements in artificial intelligence (AI), it has become possible to develop smart training solutions that rely on the analysis of biometric and physiological data to deliver personalized programs tailored to individual needs. AI algorithms can analyze users' biological and physical data and generate training regimens based on physiological responses, opening new avenues for improving …