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2025

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Old Habits Die Hard: Precedent, Psychology, And The Admissibility Of Forensic Evidence, Sara Gordon Jan 2025

Old Habits Die Hard: Precedent, Psychology, And The Admissibility Of Forensic Evidence, Sara Gordon

All Faculty Publications

Forensic evidence, long considered a cornerstone of criminal justice, has faced increasing scrutiny as recent studies and reports expose significant flaws in its scientific foundation. Techniques such as latent fingerprint analysis, microscopic hair comparison, and ballistics matching, which had been widely accepted for decades, are now being challenged for their lack of empirical validation. Reports by the National Research Council and the President’s Council of Advisors on Science and Technology have highlighted the deficiencies in these forensic methods, calling into question their reliability and the weight they are given in courtrooms. Yet despite the growing acknowledgement of widespread issues affecting …


Streaming, Copyright And Creators: A Canadian Perspective, Graham Reynolds Jan 2025

Streaming, Copyright And Creators: A Canadian Perspective, Graham Reynolds

All Faculty Publications

This paper will provide an introduction to streaming and copyright in Canada. It will proceed in five parts. Following this introduction, Part 2 of this paper will define streaming, discuss some of the benefits that flow from the widespread use of streaming services, and outline the extent to which streaming technologies are in use in Canada today. In so doing, this paper will distinguish between three types of streaming services: streaming services that secure authorization from rights-holders before making content available; streaming services that rely on technological measures or liability exemptions in order to host content in a non-infringing manner; …


Policy Forum: Are Carbon Contracts For Difference Well Suited For Canada?, Wei Cui Jan 2025

Policy Forum: Are Carbon Contracts For Difference Well Suited For Canada?, Wei Cui

All Faculty Publications

At least up to the release of the federal 2024 budget, many Canadian politicians, climate policy think tanks, and industry groups promoted carbon contracts for difference (CCfD) to complement carbon pricing. This commentary urges caution against the broad adoption of CCfDs. The author begins by noting that the current designs of provincial output-based pricing systems (OBPS) are not consistent with the expectation of the systems delivering robust price signals. He argues that CCfDs depend on such price signals, and they are not a plausible policy for encouraging the emergence of such signals. The author then argues that it is hard …


Binding Rights: Contractual Federalism And The Right To Housing In Canada, Alexandra Flynn Jan 2025

Binding Rights: Contractual Federalism And The Right To Housing In Canada, Alexandra Flynn

All Faculty Publications

Canada’s housing crisis continues to deepen, exacerbated by constitutional fragmentation and intergovernmental reluctance to implement human rights-based housing policy. While the federal National Housing Strategy Act recognizes housing as a human right, its application is limited and its legal force is limited to the federal level, leaving provinces and municipalities unbound. This article argues that contract law – particularly conditional funding agreements between the federal government and subnational actors – can serve as a pragmatic and legally coherent mechanism to bind municipalities to housing obligations, including the recognition of housing as a human right. Drawing on the Canada Health Act …


The Association Of Human Milk Intake And Outcomes In Biliary Atresia, Mary Elizabeth M Tessier, Jeremy M Schraw, Stacey Beer, Sanjiv Harpavat, M Kyle Jensen, John C Magee, Vicky Ng, Michael E Scheurer, Sarah A Taylor, Benjamin L Shneider Jan 2025

The Association Of Human Milk Intake And Outcomes In Biliary Atresia, Mary Elizabeth M Tessier, Jeremy M Schraw, Stacey Beer, Sanjiv Harpavat, M Kyle Jensen, John C Magee, Vicky Ng, Michael E Scheurer, Sarah A Taylor, Benjamin L Shneider

Faculty, Staff and Students Publications

Objectives: Human milk intake has many benefits which could influence outcomes in biliary atresia (BA). However, the role of human milk in BA has not been examined. We hypothesized that human milk intake would be associated with improved outcomes in BA.

Methods: We assessed the impact of any human milk (AHM) as compared to formula only (FO) intake before Kasai portoenterostomy (KP) on outcomes in 447 infants with BA using the PROBE database (NCT00061828) post hoc. The primary outcome was clearance of jaundice (COJ = total bilirubin (TB) < 2 mg/dL by 3 months post-KP). Secondary outcomes included 2-year survival with native liver (SNL), bilirubin levels, cholangitis, ascites, and growth. We assessed the fecal microbiome (n = 8) comparing AHM versus FO.

Results: At baseline, 211 infants received AHM and 215 received …


Evaluation Of Methotrexate Pharmacogenomic Variation To Predict Acute Neurotoxicity In Children With Acute Lymphoblastic Leukemia, Rachel D Harris, Olga A Taylor, M Monica Gramatges, Amy E Hughes, Mark Zobeck, Sandi Pruitt, M Brooke Bernhardt, Ashley Chavana, Van Huynh, Kathleen Ludwig, Laura Klesse, Kenneth Heym, Timothy Griffin, Rodrigo Erana, Juan Carlos Bernini, Ashley Choi, Yuu Ohno, Melissa A Richard, Alanna C Morrison, Han Chen, Bing Yu, Philip J Lupo, Karen Rabin, Michael E Scheurer, Austin L Brown Jan 2025

Evaluation Of Methotrexate Pharmacogenomic Variation To Predict Acute Neurotoxicity In Children With Acute Lymphoblastic Leukemia, Rachel D Harris, Olga A Taylor, M Monica Gramatges, Amy E Hughes, Mark Zobeck, Sandi Pruitt, M Brooke Bernhardt, Ashley Chavana, Van Huynh, Kathleen Ludwig, Laura Klesse, Kenneth Heym, Timothy Griffin, Rodrigo Erana, Juan Carlos Bernini, Ashley Choi, Yuu Ohno, Melissa A Richard, Alanna C Morrison, Han Chen, Bing Yu, Philip J Lupo, Karen Rabin, Michael E Scheurer, Austin L Brown

Faculty, Staff and Students Publications

BACKGROUND: Methotrexate is an important component of curative therapy in childhood acute lymphoblastic leukemia (ALL), but the role of genetic variation influencing methotrexate clearance and transport in toxicity susceptibility in children with ALL is not well established. Therefore, we evaluated the association between suspected methotrexate pharmacogenomic variants and methotrexate-related neurotoxicity.

METHODS: This study included children (aged 2-20 years) diagnosed with ALL (2005-2019) at six treatment centers in the southwest United States. Clinical information was abstracted from medical records. Suspected neurotoxic events occurring within 21 days of intravenous and/or intrathecal methotrexate delivered between the end of induction and start of maintenance …


Designing And Implementing Solution-Oriented Team Science Initiatives-A Chronic Pain Example, Nele A Haelterman, Armen N Akopian, Kyle D Allen, Yenisel Cruz-Almeida, Christopher R Donnelly, Brendan Lee, Rebecca Lenzi, Anne-Marie Malfait, Marie Mancini, Maryann E Martone, Joost B Wagenaar, Kim C Worley Jan 2025

Designing And Implementing Solution-Oriented Team Science Initiatives-A Chronic Pain Example, Nele A Haelterman, Armen N Akopian, Kyle D Allen, Yenisel Cruz-Almeida, Christopher R Donnelly, Brendan Lee, Rebecca Lenzi, Anne-Marie Malfait, Marie Mancini, Maryann E Martone, Joost B Wagenaar, Kim C Worley

Faculty, Staff and Students Publications

Large, collaborative projects that combine researchers from multiple scientific disciplines have become an integral part of the scientific endeavor. While transdisciplinary team science projects hold great potential, they also come with a unique set of challenges compared to monodisciplinary projects. The Science of Team Science (SciTS) field has developed multiple conceptual models and frameworks that guide the design, implementation, and evaluation of team science initiatives to maximize their potential for making breakthrough discoveries and creating solutions for complex problems. While these conceptual models contain a trove of valuable information for successful team science, guidance on how to effectively implement them …


Nanoparticle Contrast Agents For Photon-Counting Computed Tomography: Recent Developments And Future Opportunities, Laxman Devkota, Rohan Bhavane, Cristian T Badea, Eric A Tanifum, Ananth V Annapragada, Ketan B Ghaghada Jan 2025

Nanoparticle Contrast Agents For Photon-Counting Computed Tomography: Recent Developments And Future Opportunities, Laxman Devkota, Rohan Bhavane, Cristian T Badea, Eric A Tanifum, Ananth V Annapragada, Ketan B Ghaghada

Faculty, Staff and Students Publications

The clinical availability of photon-counting computed tomography (PCCT) has ushered in a new era of CT imaging. Spectral imaging coupled with superior contrast resolution, and ultrahigh spatial resolution (200 μm) offered by PCCT has the potential to revolutionize value-driven imaging. The potential of multicolor PCCT has generated excitement, and renewed interest, in novel contrast agent development for comprehensive disease interrogation, prediction and monitoring of treatment outcomes. Nanoparticles provide a versatile and powerful platform for the development of next generation contrast agents for spectral PCCT. In this article, we review recent developments and use of nanoparticle contrast agents for PCCT. We …


Mutations In Retinal Cyclic Nucleotide-Gated Channels Identified In Familial Cases Of Inherited Retinal Dystrophies From Pakistan, Zainab Akhtar, Kiran Afshan, Yumei Li, Sumaira Altaf, Aleesha Asghar, Ume Sughra, Wajid Ali Khan, Haiba Kaul, Rui Chen, Sabika Firasat Jan 2025

Mutations In Retinal Cyclic Nucleotide-Gated Channels Identified In Familial Cases Of Inherited Retinal Dystrophies From Pakistan, Zainab Akhtar, Kiran Afshan, Yumei Li, Sumaira Altaf, Aleesha Asghar, Ume Sughra, Wajid Ali Khan, Haiba Kaul, Rui Chen, Sabika Firasat

Faculty, Staff and Students Publications

Purpose: Cyclic nucleotide-gated (CNG) channels are ligand-gated ion channels that transduce light signals into electrical signals in the retinal photoreceptors. Pathogenic variants in CNG channel genes are reported to cause inherited retinal dystrophies (IRDs). The current study used targeted panel sequencing to describe the mutational spectrum of CNG channel genes in familial cases of IRDs from eight consanguineous Pakistani families.

Methods: The current study included consanguineous Pakistani families with at least two affected members. DNA was extracted from whole blood samples by the phenol-chloroform method. Two affected members from each family were initially analyzed using targeted panel sequencing of 344 …


Towards A Map Of The Immune System Manipulation Network By Trypanosoma Cruzi, Juan Cruz Gamba, Ana Rosa Pérez, Carolina Verónica Poncini, Cristina Poveda, Iván Marcipar, Gabriel Cabrera Jan 2025

Towards A Map Of The Immune System Manipulation Network By Trypanosoma Cruzi, Juan Cruz Gamba, Ana Rosa Pérez, Carolina Verónica Poncini, Cristina Poveda, Iván Marcipar, Gabriel Cabrera

Faculty, Staff and Students Publications

No abstract provided.


Incidence And Outcomes Of Hospitalized Acute Ischemic Stroke Patients With Subsequent St-Segment-Elevation Myocardial Infarction, Arhum Mahmood, Song Peng Ang, Yusuf Kamran Qadeer, Hafeez Ul Hassan Virk, Jonathan Alan Tangsrivimol, Iqra Riaz, Zhen Wang, Mahboob Alam, Markus Strauss, Chayakrit Krittanawong Jan 2025

Incidence And Outcomes Of Hospitalized Acute Ischemic Stroke Patients With Subsequent St-Segment-Elevation Myocardial Infarction, Arhum Mahmood, Song Peng Ang, Yusuf Kamran Qadeer, Hafeez Ul Hassan Virk, Jonathan Alan Tangsrivimol, Iqra Riaz, Zhen Wang, Mahboob Alam, Markus Strauss, Chayakrit Krittanawong

Faculty, Staff and Students Publications

Background: Patients admitted with acute ischemic stroke (AIS) may experience accompanying acute ST-Segment myocardial infarction after AIS. The cardiovascular risks, incidence, complications, and outcomes of acute STEMI in patients hospitalized with AIS remains underexplored.

Methods: We evaluated 2,804,819 patients that presented with AIS who were listed in the National Inpatient Sample from 2016 to 2021. AIS and STEMI were defined according to the ICD-10 Diagnostic Codes. Patients with Non-STEMI were excluded. The risk of specific complications and outcomes were expressed as percentages. Multivariable logistic regression analysis was used to examine the association of STEMI with a primary outcome of mortality …


Stent Thrombosis: A Contemporary Guide To Definitions, Risk Factors, And Management, Ambre Flowers, Bernard Evenhuis, Benjamin Gabanic, Allison Weiss, Scott Eisenberg, Riyan Siddiqui, Affan Rizwan, Iqra Riaz, Hafeez Ul Hassan Virk, Mahboob Alam, Muzamil Khawaja, Markus Strauss, Chayakrit Krittanawong Jan 2025

Stent Thrombosis: A Contemporary Guide To Definitions, Risk Factors, And Management, Ambre Flowers, Bernard Evenhuis, Benjamin Gabanic, Allison Weiss, Scott Eisenberg, Riyan Siddiqui, Affan Rizwan, Iqra Riaz, Hafeez Ul Hassan Virk, Mahboob Alam, Muzamil Khawaja, Markus Strauss, Chayakrit Krittanawong

Faculty, Staff and Students Publications

Stent thrombosis remains a major complication following percutaneous coronary intervention, with significant morbidity and mortality implications. Despite advancements in drug-eluting stents and optimized pharmacotherapy, real-world registry data indicate that definite or probable stent thrombosis occurs in approximately 0.5% of percutaneous coronary intervention cases, with a 30-day mortality rate approaching 25% and a long-term risk exceeding 30% at 10 years. Stent thrombosis is classified based on timing into acute, subacute, late, and very late thrombosis, with subacute and very late stent thrombosis being the most prevalent. Clinical consequences include myocardial infarction, emergent revascularization, and heightened cardiovascular risk, necessitating timely recognition and …


Testosterone Plus Lifestyle Therapy Improves Skeletal Muscle Glycolysis In Older Men With Obesity And Hypogonadism, Viola Viola, Marlene Aguilar, Maria Liza Duremdes Nava, Alessandra Celli, Reina Armamento-Villareal, Yoann Barnouin, Nicola Napoli, Nagireeddy Putluri, Clifford Qualls, Dennis T Villareal Jan 2025

Testosterone Plus Lifestyle Therapy Improves Skeletal Muscle Glycolysis In Older Men With Obesity And Hypogonadism, Viola Viola, Marlene Aguilar, Maria Liza Duremdes Nava, Alessandra Celli, Reina Armamento-Villareal, Yoann Barnouin, Nicola Napoli, Nagireeddy Putluri, Clifford Qualls, Dennis T Villareal

Faculty, Staff and Students Publications

Objective: Weight loss in older men with obesity and hypogonadism accelerates musculoskeletal decline, yet the underlying metabolic mechanisms remain unclear. Testosterone replacement therapy (TRT), when added to lifestyle therapy (LT), mitigates this decline, but its metabolic basis has not been defined. We examined skeletal muscle metabolomic adaptations to LT with or without TRT, focusing on glycolysis, the pentose phosphate pathway (PPP), the tricarboxylic acid (TCA) cycle, and carnitine metabolism to identify dominant pathways of metabolic adaptation.

Design: Randomized, double-blind, placebo-controlled trial (LITROS).

Methods: Eighty-three men aged 65 years or older with obesity (BMI ≥30 kg/m2), hypogonadism (testosterone < 10.4 nmol/L), and frailty (Physical Performance Test score ≤31) were randomized to 26 weeks of LT plus TRT (LT+TRT) or LT plus placebo (LT+Pbo). A metabolomic substudy was performed in 44 participants, who underwent serial biopsies of the vastus lateralis for targeted LC-MS/MS analysis of intermediates in glycolysis, PPP, TCA cycle, and carnitine metabolism.

Results: Among the …


Clues To Transcription/Replication Collision-Induced Dna Damage: It Was Rnap, In The Chromosome, With The Fork, Matthew B Cooke, Christophe Herman, Priya Sivaramakrishnan Jan 2025

Clues To Transcription/Replication Collision-Induced Dna Damage: It Was Rnap, In The Chromosome, With The Fork, Matthew B Cooke, Christophe Herman, Priya Sivaramakrishnan

Faculty, Staff and Students Publications

DNA replication and RNA transcription processes compete for the same DNA template and, thus, frequently collide. These transcription-replication collisions are thought to lead to genomic instability, which places a selective pressure on organisms to avoid them. Here, we review the predisposing causes, molecular mechanisms, and downstream consequences of transcription-replication collisions (TRCs) with a strong emphasis on prokaryotic model systems, before contrasting prokaryotic findings with cases in eukaryotic systems. Current research points to genomic structure as the primary determinant of steady-state TRC levels and RNA polymerase regulation as the primary inducer of excess TRCs. We review the proposed mechanisms of TRC-induced …


Folate Receptor Β Performs An Immune Checkpoint Function In Activated Macrophages, Fenghua Zhang, Md Yusuf Al-Amin, Sagar Utturkar, Rina Jiang, Gregory Cresswell, Rami Alfar, Ian Ophaug-Johansen, Gabriel Bachman, Madduri Srinivasarao, Richard Finnell, Amaya Puig-Kröger, Timothy Ratliff, Philip S Low Jan 2025

Folate Receptor Β Performs An Immune Checkpoint Function In Activated Macrophages, Fenghua Zhang, Md Yusuf Al-Amin, Sagar Utturkar, Rina Jiang, Gregory Cresswell, Rami Alfar, Ian Ophaug-Johansen, Gabriel Bachman, Madduri Srinivasarao, Richard Finnell, Amaya Puig-Kröger, Timothy Ratliff, Philip S Low

Faculty, Staff and Students Publications

Monocytes and macrophages are sentinels of the immune system that distinguish themselves from other cells by expressing the beta isoform of the folate receptor (FRβ). Because FRβ does not bind folate until the monocyte/macrophage is exposed to immunosuppressive cytokines, the question naturally arose whether FRβ might also perform an immune-related function. To examine this matter, we compared the properties of wild type (WT) and FRβ knockout mice. We observe that FRβ knockout (KO) mice display autoimmune symptoms that can include alopecia, enlarged spleens, and dermatitis, despite having normal cellular folate levels. We further demonstrate that syngeneic tumors (TRAMP C2, MC38) …


The Enigmatic Pianist Arthur Friedheim: A Revised Biography And Study Of His Training, Performing, Writings, Teaching And Editions, Nicholas Mark Williams Jan 2025

The Enigmatic Pianist Arthur Friedheim: A Revised Biography And Study Of His Training, Performing, Writings, Teaching And Editions, Nicholas Mark Williams

Theses: Doctorates and Masters

Arthur Friedheim (1859–1932) was one of the most notable pianists of the late nineteenth century, best remembered as a devoted pupil and disciple of Franz Liszt (1811–1886). Following Friedheim’s Leipzig debut in 1884, Liszt predicted that his young pupil “would yet become the greatest piano virtuoso of the age.” During his lifetime, Friedheim would be compared with such pianistic giants as Carl Tausig (1841–1871), Moriz Rosenthal (1862–1946) and Ferruccio Busoni (1866–1924). Yet his posthumous reception, based on a few surviving recordings and a small number of written sources, has tended to cast doubt on his importance. Some critics disparagingly dismissed …


Athlete Monitoring And Training Modification Decision-Making: Insights From High-Level Endurance Sports Coaches, Wouter Piet Timmerman Jan 2025

Athlete Monitoring And Training Modification Decision-Making: Insights From High-Level Endurance Sports Coaches, Wouter Piet Timmerman

Theses: Doctorates and Masters

Athlete monitoring technology has proliferated in the last decades. However, much of what is known about athlete monitoring tends to come from unpublished personal experiences and anecdotal information. In the last decade, considerable athlete monitoring research has been conducted, leading to multiple reviews and consensus statements mainly on athlete monitoring tools and methods. Recognising that athlete monitoring is a human-driven process, typically with the coach as the decision-maker, it is imperative to study coaches given their extensive knowledge and expertise. The overall aim of the thesis was to gain insights into why and how high-level endurance sports coaches use athlete …


Barriers And Motivators To Attending Group Exercise Classes In Women With Anxiety, Depression And Post-Traumatic Stress Disorder, Sarah Ford Jan 2025

Barriers And Motivators To Attending Group Exercise Classes In Women With Anxiety, Depression And Post-Traumatic Stress Disorder, Sarah Ford

Theses: Doctorates and Masters

Research has demonstrated the positive effect of exercise on mental health disorders such as anxiety disorder, depression and post-traumatic stress disorder. Studies have also investigated the barriers and motivators that women in particular experience when contemplating the ways in which to engage in physical activity. However, a literature gap exists regarding women who experience anxiety disorder, depression and post-traumatic stress disorder, and the barriers and motivators that they specifically navigate when looking to attend group exercise classes. In this body of research for the award of Master of Medical and Health Science by Research, a scoping review was first conducted …


The Interplay Between Injury And Body Composition With Performance In Police Recruits, Vanessa Sutton Jan 2025

The Interplay Between Injury And Body Composition With Performance In Police Recruits, Vanessa Sutton

Theses: Doctorates and Masters

The occupational demands of policing are challenging and potentially hazardous, with substantial rates of musculoskeletal injuries occurring during recruit training. Academy injury prevalence can be as high as one in five recruits. Injuries impact performance, result in lost training, and impose financial burdens on police agencies. However, limited research has explored pre-injury body composition or musculoskeletal characteristics in relation to police recruit performance. This thesis investigates injuries, body composition and musculoskeletal characteristics in physical performance and injury risk among law enforcement recruits.

Study One quantified prevalence and severity of pre-academy injuries and association with performance. Among 121 recruits, nearly half …


Wavelength Multiplexed Volume Holographic Optical Couplers To Couple Red, Green And Blue Light For Solar Collection, Dipanjan Chakraborty, Rosen Georgiev, Vincent Toal, Izabela Naydenova, Dervil Cody, Suzanne Martin Jan 2025

Wavelength Multiplexed Volume Holographic Optical Couplers To Couple Red, Green And Blue Light For Solar Collection, Dipanjan Chakraborty, Rosen Georgiev, Vincent Toal, Izabela Naydenova, Dervil Cody, Suzanne Martin

Research Outputs: 2025-Present

The proposed wavelength multiplexed, volume holographic optical coupler uses total internal reflection to guide incident light of a wavelength from 317nm to 700nm. The diffractive elements are recorded with 457nm (transmission holographic recording) and 532nm (reflection holographic recording) lasers in Bayfol HX 200TM photopolymer. The novelty of the device is the particular combination of diffractive optical elements designed so that they can be holographically recorded with two different wavelengths without the need for prisms to facilitate the propagation of the recording beam in the recording layer at angles exceeding the internal critical angle. and will couple three primary colours …


Investigating The Anisotropic Effects On Machining Behavior And Performance Of As-Built Selective Laser Melting Processed Ti6al4v Alloy, Surinder Pal, Xavier Velay, Waqas Saleem, Muhammad Faisal Rathore Jan 2025

Investigating The Anisotropic Effects On Machining Behavior And Performance Of As-Built Selective Laser Melting Processed Ti6al4v Alloy, Surinder Pal, Xavier Velay, Waqas Saleem, Muhammad Faisal Rathore

Research Outputs: 2025-Present

This study examines how the natural anisotropy of as-build Ti6Al4V, fabricated using Selective Laser Melting, affects its machining behavior, specifically focusing on hardness and microstructure behavior. Milling experiments were carried out to understand how the anisotropy material responds to machining and its impact on the final surface finish. Advanced techniques, including FE-SEM, were employed to analyze the microstructure, revealing intricate microstructural details. EDS was used to assess the elemental composition of the materials. Additionally, hardness testing was conducted to evaluate the mechanical properties, highlighting the effects of anisotropic behavior on the alloy’s performance characteristics. The findings underscore the significance of …


An Experimental Investigation Of The Effect Of The Velocity Ratio On The Flow And Wall Heat Transfer Characteristics Of A Wall-Bounded Dual Jet, Paula J. Murphy, Sajad Alimohammadi, Séamus M. O'Shaughnessy Jan 2025

An Experimental Investigation Of The Effect Of The Velocity Ratio On The Flow And Wall Heat Transfer Characteristics Of A Wall-Bounded Dual Jet, Paula J. Murphy, Sajad Alimohammadi, Séamus M. O'Shaughnessy

Research Outputs: 2025-Present

A wall-bounded dual jet, consisting of a wall jet and a co-flowing offset jet, possesses a complex flow structure that has proved advantageous across many industrial applications. Despite this, dual jets remain relatively unexplored through experimentation and their flow phenomena are largely misunderstood. This investigation is the first to examine the effect of varying the velocity ratio (Vr) on the flow and heat transfer behaviour of a dual jet through experimental means. A velocity ratio range of 0.5≤Vr≤2 is achieved by varying each jet Reynolds number (Rew/o) in the range 5500≤Rew/o≤12,000. Infrared …


Challenges In Adapting Fibre Optic Sensors For Biomedical Applications, Sahar Karimian, Muhammad Mahmood Ali, Marion Mcafee, Waqas Saleem, Dineshbabu Duraibabu, Sanober Farheen Memon, Elfed Lewis Jan 2025

Challenges In Adapting Fibre Optic Sensors For Biomedical Applications, Sahar Karimian, Muhammad Mahmood Ali, Marion Mcafee, Waqas Saleem, Dineshbabu Duraibabu, Sanober Farheen Memon, Elfed Lewis

Research Outputs: 2025-Present

Fibre optic sensors (FOSs) have developed as a transformative technology in healthcare, often offering unparalleled accuracy and sensitivity in monitoring various physiological and biochemical parameters. Their applications range from tracking vital signs to guiding minimally invasive surgeries, enabling advancements in medical diagnostics and treatment. However, the integration of FOSs into biomedical applications faces numerous challenges. This article describes some challenges for adopting FOSs for biomedical purposes, exploring technical and practical obstacles, and examining innovative solutions. Significant challenges include biocompatibility, miniaturization, addressing signal processing complexities, and meeting regulatory standards. By outlining solutions to the stated challenges, it is intended that this …


Heat Generation In Perovskite/Cztsse Tandem Solar Cells, Mohammad Bahrami, Mohammad Mahdi Najafali, Javad Maleki, Fatemeh Khalaji, Mansour Kanani, Mohammad Moaddeli, Nima Ghadiri Jan 2025

Heat Generation In Perovskite/Cztsse Tandem Solar Cells, Mohammad Bahrami, Mohammad Mahdi Najafali, Javad Maleki, Fatemeh Khalaji, Mansour Kanani, Mohammad Moaddeli, Nima Ghadiri

Research Outputs: 2025-Present

Tandem of Perovskite and other materials for solar cell structure have attracted the attention of many researchers. Here, we developed a strong coupled model to investigate the heat generation and thermal stability of Perovskite/CZTSSe Tandem Solar Cells. Studying the opto-electro-thermal (OET) properties of tandem solar cells is essential to better understand the optical absorption, carrier transport, and their thermodynamic behavior. In recent years, thermal losses in solar cells have received more attention and heat generation in solar cell structure has said to be effective on long-term stability and performance. Temperature distribution and heat generation of tandem solar cells has been …


Hydrothermal Behavior Of A Novel Conical Twisted Strip Turbulator In A Heated Tube: A Numerical Analysis, Azher M. Abed, Bhavesh Kanabar, T. Ramachandran, Aman Shankhyan, Jasgurpreet Singh Chohan, A. Karthikeyan, Deepak Gupta, Bashir Salah, Waqas Saleem Jan 2025

Hydrothermal Behavior Of A Novel Conical Twisted Strip Turbulator In A Heated Tube: A Numerical Analysis, Azher M. Abed, Bhavesh Kanabar, T. Ramachandran, Aman Shankhyan, Jasgurpreet Singh Chohan, A. Karthikeyan, Deepak Gupta, Bashir Salah, Waqas Saleem

Research Outputs: 2025-Present

The increasing use of heated pipes and heat exchangers has created a pressing need to enhance thermal efficiency. This research introduces a novel turbulator design known as the conical twisted strip turbulator. The turbulator design resembles a cone and is composed of several twisted strip tentacles. This unique configuration is expected to generate strong rotational and radial flow patterns, leading to enhanced heat transfer. A numerical analysis was conducted using the RNG k-epsilon model to investigate various geometric parameters of the turbulator. The study examined the twisted angle, which varied from 60 to 270°, the number of twisted strip tentacles, …


Aspen Plus Modelling Of The Milena Dual Fluidised Bed Biomass Gasifier Technology, Mohadeseh Naderi, Hamid Rashidi, Anthony Reynolds, Wayne Doherty Jan 2025

Aspen Plus Modelling Of The Milena Dual Fluidised Bed Biomass Gasifier Technology, Mohadeseh Naderi, Hamid Rashidi, Anthony Reynolds, Wayne Doherty

Research Outputs: 2025-Present

The Energy Research Centre of The Netherlands is developing MILENA gasification technology to convert biomass fuels into high-value gaseous and liquid products. MILENA is a steam-blown dual fluidised bed (DFB) gasification process with separate gasification and combustion zones. This DFB gasifier produces high-quality gas with low N2 content suitable for vehicle fuel or natural gas grid injection. This study presents a semi-kinetic Aspen Plus model for MILENA gasification, including stages like drying, rapid pyrolysis, gasification, combustion, and tar cracking and reforming. Pyrolysis as a key step, was modelled using experimental data for the rapid pyrolysis of wood to calculate …


Numerical Methodologies For The Analysis Of Horizontal-Axis Floating Offshore Wind Turbines (F-Hawts): A State-Of-The-Art Review, Naghmeh Akbari Zadeh, Peter Ryan, David M. Kennedy, Fergal O’Rourke Jan 2025

Numerical Methodologies For The Analysis Of Horizontal-Axis Floating Offshore Wind Turbines (F-Hawts): A State-Of-The-Art Review, Naghmeh Akbari Zadeh, Peter Ryan, David M. Kennedy, Fergal O’Rourke

Research Outputs: 2025-Present

In recent decades, wind turbine installations have become a popular option to meet the world’s growing demand for energy. Both onshore and offshore wind turbines form pivotal components of the electricity sector. Onshore wind energy is now a mature technology, with significant experience gained by wind farm developers and operators over the last couple of decades. However, as a more recent enterprise, the offshore wind industry still requires significantly more development before the technologies and operations reach maturity. To date, floating platforms at sea have been utilised extensively for the oil and gas industry. While a lot of the expertise …


Factors Associated With Contraceptive Discontinuation Among Women In The U.S., Moradi Aljadani Jan 2025

Factors Associated With Contraceptive Discontinuation Among Women In The U.S., Moradi Aljadani

Electronic Theses and Dissertations 2020 - Present

Background: Contraceptive discontinuation is a significant public health concern in the United States, contributing to unintended pregnancies and associated health, social, and economic consequences. Despite the availability of a wide range of contraceptive methods, many women discontinue use prematurely due to a variety of personal, social, cultural, and systemic factors. However, limited research has comprehensively examined these factors at the national level, particularly within a theoretical framework that captures the multidimensional influences on contraceptive decision-making. Objective: This study aimed to assess the factors associated with contraceptive method discontinuation among women in the U.S, guided by Ray’s Theory f …


“Thank You For Hearing Me”: Listening To Stories Of Linguicism, Caroline Asher Webb Jan 2025

“Thank You For Hearing Me”: Listening To Stories Of Linguicism, Caroline Asher Webb

Electronic Theses and Dissertations 2020 - Present

This dissertation examines the effects of linguicism on nonnative speakers of English who are currently studying in higher education in the United States or other English-dominant countries. Linguicism, also called linguistic discrimination, others and discriminates against people based on their oral or written language use. Rooted in master narratives of Standard English, monolingualism, and the native speaker, linguicism, unlike other forms of discrimination, such as gender or racial discrimination, is subtle and unmarked, thus permeating the consciousness of even the most well-intentioned of people.

Using a Critical Race Theory framework, the present study utilized a storytelling methodology to gather first-hand …


You Are Safe Here: A Phenomenological Exploration Of Psychological Safety And Organizational Ombuds In Higher Education, Angella J. Wint Jan 2025

You Are Safe Here: A Phenomenological Exploration Of Psychological Safety And Organizational Ombuds In Higher Education, Angella J. Wint

Electronic Theses and Dissertations 2020 - Present

This qualitative phenomenological study aimed to better understand the nature of ombuds’ psychological safety experiences in higher education by exploring how ombuds make meaning of their lived experiences with psychological safety and how it informs their roles with the constituencies they serve in higher education. Relying on data gathered related to the lived experiences of 12 organizational ombuds working at institutions of higher education, this study utilized one-on-one, open-ended, semi-structured interviews to collect data. The Four Stages of Psychological Safety was the conceptual framework used to study participants’ lived experiences. This study will contribute to the limited published empirical research …