Digital Commons Network^™

A Serum Biomarker Panel And Miniarray Detection System For Tracking Disease Activity And Flare Risk In Lupus Nephritis, Chenling Tang, Gongjun Tan, Aygun Teymur, Jiechang Guo, Arturo Haces-Garcia, Weihang Zhu, Richard Williams, Jing Ning, Ramesh Saxena, Tianfu Wu

Faculty, Staff and Student Publications

Introduction: Lupus nephritis (LN) leads to end stage renal disease (ESRD), and early diagnosis and disease monitoring of LN could significantly reduce the risk. however, there is not such a system clinically. In this study we aim to develop a biomarker-panel based point-of-care system for LN.

Methods: Immunoassay screening combined with genomic expression databases and machine learning techniques was used to identify a biomarker panel of LN. A quantitative biomarker-panel mini-array (BPMA) system was developed and the sensitivity, specificity, reproducibility, and stability of the were examined. The performance of BPMA in disease monitoring was validated with machine models using a …

Impact Of Pre-Transplant Immune Checkpoint Inhibitor Use On Post-Transplant Outcomes In Hcc: A Systematic Review And Individual Patient Data Meta-Analysis, Mohammad Saeid Rezaee-Zavareh, Yee Hui Yeo, Tielong Wang, Zhiyong Guo, Parissa Tabrizian, Stephen C Ward, Fatma Barakat, Tarek I Hassanein, Shravan Dave, Veeral Ajmera, Sherrie Bhoori, Vincenzo Mazzaferro, David M H Chascsa, Margaret C Liu, Elizabeth S Aby, John R Lake, Miguel Sogbe, Bruno Sangro, Maen Abdelrahim, Abdullah Esmail, Andreas Schmiderer, Yasmina Chouik, Mark Rudolph, Davendra Sohal, Heloise Giudicelli, Manon Allaire, Mehmet Akce, Jessica Guadagno, Clara Y Tow, Hatef Massoumi, Paolo De Simone, Elise Kang, Robyn D Gartrell, Mercedes Martinez, Ricardo Paz-Fumagalli, Beau B Toskich, Nguyen H Tran, Gabriela Azevedo Solino, Dra Mariana Poltronieri Pacheco, Richard S Kalman, Vatche G Agopian, Neil Mehta, Neehar D Parikh, Amit G Singal, Ju Dong Yang

Faculty, Staff and Student Publications

Background & aims: Treatment with immune checkpoint inhibitors (ICIs) for hepatocellular carcinoma (HCC) prior to liver transplantation (LT) has been reported; however, ICIs may elevate the risk of allograft rejection and impact other clinical outcomes. This study aims to summarize the impact of ICI use on post-LT outcomes.

Methods: In this individual patient data meta-analysis, we searched databases to identify HCC cases treated with ICIs before LT, detailing allograft rejection, HCC recurrence, and overall survival. We performed Cox regression analysis to identify risk factors for allograft rejection.

Results: Among 91 eligible patients, with a median (IQR) follow-up of 690.0 (654.5) …

Navigating The Nexus Of Food Insecurity, Anxiety, And Depression In The Face Of Climate Change: A Longitudinal Study In Rural Kenya, Michael Goodman, Lauren Raimer-Goodman, Heidi M Hagen Mcpherson, Dawit Woldu, Shreela Sharma, Ryan Ramphul, Fridah Mukiri, Agnes Maigallo

Faculty, Staff and Student Publications

Objective: This study aims to address critical gaps in understanding the bidirectional relationships between food insecurity, anxiety, and depression in Meru County, Kenya. By employing a cross-lagged panel analysis, we seek to clarify these temporal dynamics, contributing to the design of targeted interventions that integrate food security and mental health in the context of climate change.

Methods: A cross-lagged panel analysis was conducted using data from 362 adult participants in a community-based empowerment program (2023) in Meru County, Kenya. Participants completed self-report measures of food insecurity, anxiety, and depression at two time points, 11 weeks apart.

Results: Food insecurity (T1) …

Prediction Of Preterm Birth Among Infants With Orofacial Cleft Defects, Katherine L Ludorf, Renata H Benjamin, Mark A Canfield, Michael D Swartz, A J Agopian

Faculty, Staff and Student Publications

Objective: To develop risk prediction models for preterm birth among infants with orofacial clefts.

Design: Data from the Texas Birth Defects Registry for infants with orofacial clefts born between 1999-2014 were used to develop preterm birth predictive models. Logistic regression was used to consider maternal and infant characteristics, and internal validation of the final model was performed using bootstrapping methods. The area under the curve (AUC) statistic was generated to assess model performance, and separate predictive models were built and validated for infants with cleft lip and cleft palate alone. Several secondary analyses were conducted among subgroups of interest.

Setting: …

Effect Of Digital Health Coaching On Self-Efficacy And Patient-Reported Outcomes In Individuals With Acute Myeloid And Chronic Lymphocytic Leukemia: A Pilot Randomized Controlled Trial, Jennifer Marvin-Peek, Valerie Shelton, Kelly Brassil, Bryan Fellman, Austin Barr, Kelly Sharon Chien, Danielle Hammond, Mahesh Swaminathan, Nitin Jain, William Wierda, Alessandra Ferrajoli, Courtney Dinardo

Faculty, Staff and Student Publications

Introduction: Promotion of self-efficacy can enhance engagement with health care and treatment adherence in patients with cancer. We report the outcomes of a pilot trial of a digital health coach intervention in patients with leukemia with the aim of improving self-efficacy.

Methods: Adult patients with newly diagnosed acute myeloid leukemia (AML) and chronic lymphocytic leukemia (CLL) were randomized 1:1 to a digital health coach intervention or standard of care. The primary outcome of self-efficacy was measured by the Cancer Behavior Inventory (CBI) score.

Results: A total of 147 patients (37 AML, 110 CLL) were enrolled from July 2020 to December …

Perspectives On Smoking Cessation In The Oncology Environment: Insights From Brazilian Patients And Healthcare Providers, Raquel Descie Veraldi Leite, Ricardo Ribeiro Gama, Fabiana De Lima Vazquez, Gabriela Beltrami Massarão, Raiany Carvalho, Renan De Jesus Teixeira, Vinicius De Lima Vazquez, Irene Tami-Maury

Faculty, Staff and Student Publications

Objective: The aim of this study was to identify barriers and facilitators to smoking cessation among Brazilian cancer patients, considering the perspectives of both patients and healthcare professionals at a leading oncology center in the country.

Methods: A cross-sectional study was conducted, collecting smoking-related data from two groups: cancer patients and healthcare professionals at the Barretos Cancer Hospital (BCH) between 2019 and 2021. The questionnaire for healthcare professionals was adapted from the 2012 International Association for the Study of Lung Cancer and the Global Adult Tobacco Survey. For the cancer patient group, sociodemographic and clinical data were collected, along with …

Hit Me, Baby, One More Time: A Critical Discourse Analysis Of The Celebrity Gossip Magazine Shaming Of Britney Spears, Anna Drabik

Comm-entary

Britney Spears is an American pop star who rose to fame in the late 1990s at the age of 17 with her music, performances, and fashion. Spears was a prominent figure.

in celebrity gossip magazines, a genre which grew to prominence alongside and, in many ways, because of Spears. The distinct aesthetic and style of celebrity gossip magazines involved stories, blurbs, and images which wielded praise and shame—directly and indirectly—as tools to enforce norms and expectations for both female celebrities and female readers. Through a critical discourse analysis of 378 People and Us articles throughout the first ten years of …

Egalitarianism Is Not Equality: Moving From Outcome To Process In The Study Of Human Political Organisation, Duncan Stibbard-Hawkes, Christopher Von Rueden

Jepson School of Leadership Studies articles, book chapters and other publications

Many traditional subsistence groups have been described as ‘egalitarian societies’. Definitions of ‘egalitarianism’, especially beyond anthropology, have often emphasised equality in resource access, prestige or rank, alongside generalised preferences for fairness and equality. However, there are no human societies where equality is genuinely realised in all areas of life. Here we demonstrate, empirically, that nominally egalitarian societies are often unequal across seven important interconnected domains: embodied capital, social capital, leadership, gender, age/knowledge, material capital/land tenure, and reproduction. We also highlight evidence that individuals in nominally egalitarian societies do not unfailingly adhere to strong equality preferences. We propose a new operational …

Diversity In United States Dementia Prevention Trials: An Updated Systematic Review Of Eligibility Criteria And Recruitment Strategies, Najoua Lazaar, Sabine E Van Beek, Awaale F Rirash, Janne M Papma, Jaime Perales-Puchalt, Ashley R Shaw, Eric D Vidoni, Sanne Franzen

Faculty, Staff and Student Publications

Introduction: Given the elevated dementia risk in underrepresented demographic groups in the USA - particularly in Latino and Non-Latino Black individuals compared to Non-Latino White individuals - it is vital that these groups are well-represented in dementia prevention research. Eligibility criteria and recruitment strategies may play a key role in promoting participant diversity. The aim of this review was to examine eligibility criteria and recruitment strategies in US dementia prevention trials in light of participant diversity.

Methods: A systematic review was conducted using Medline (including PubMed), Embase, Cochrane Library, and CINAHL. We explored the percent White participants for trials using …

Assessing The “Plateaus” Vertical Development Model With A New Likert Scale Instrument, Mark Divine

Theses and Dissertations

This research project will focus on the assessment of the Five Plateaus (Plateaus) vertical leadership development model with a newly constructed Likert Scale instrument. Part one of the research project was a pilot study to create a simple, internet-based instrument. The scale, comprised of 100 questions and completed in 30 minutes, assesses participants' self- perceived stage of development as presented in the Plateaus vertical development model. The instrument was designed to capture the experience of participants and to overcome limitations of existing assessments by mitigating the subjectivity of sentence completion instruments, as well as to enhance efficiency and reliability. The …

Best Practices In Leadership In Probation, Ronamae Panganiban

Theses and Dissertations

Research indicates that leadership in law enforcement is a continuous learning process (Birzer et al., 2016; Davies & Heysmand, 2021; Niles et al., 2024; Roberts et al., 2016). Due to the complex structure and changing environment, leadership responsibilities fall upon multiple individuals in a chain of command (C. Davis, 2020; G. W. Garner, 2016; Sienkiewicz-Malyjurek, 2016). The research study aimed to identify best practices for leadership in law enforcement that leaders employ that make them successful. It used a phenomenological qualitative design and purposive sampling method to obtain a sample size of 15 participants. The study utilized a semi structured …

Farmers' Experiences Of Transitioning Towards Agroecology: Narratives Of Change In Western Europe, Maria Markiewicz-Keszycka, Áine Macken-Walsh, Aileen Carter, Simon Mooney, Emma J. Devereux, Maeve Henchion, Paul Hynds

Conference papers

Transitioning to agroecology on dairy and beef farms is touted as a sustainable response to environmental externalities. The current study conducted narrative interviews with farmers who transitioned towards agroecological food production by implementing pro-environmental diversification measures in the Republic of Ireland, the United Kingdom and France. The study aimed to determine farmers' experiences of agroecology and used a thematic approach for the analysis. Results indicate that the motivations, values and principles of farmers transitioning to agroecology are closely aligned with the ideology of the new/peasantry. Farmers' decisions were primarily influenced by ecological principles and a sense of responsibility towards environmental …

L-Theanine Modulates Stress Physiology And Immunology In Nile Tilapia, Sammie Miller, Lindee Mason, Shah Sumaiya Khaled, Elena Deng, Ahmed Mustafa

Mansoura Veterinary Medical Journal

Background: Fish are a prominent food source within the growing aquaculture industry, particularly within recirculating aquaculture systems, to alleviate global hunger demands. Diminishing detrimental stress conditions such as overcrowding prevalence and chemical toxins remain a primary goal. Nutraceuticals, particularly L-theanine, pose a natural alternative solution to alleviate these conditions. The amino acid L-theanine was scrutinized as a potential nutraceutical additive within commercial feed within the diet of Nile tilapia, Oreochromis niloticus, subjected to stress and unstressed in-vivo conditions.

Methods: To accomplish this, both 0.004% of body weight of L-theanine and 0.01% of body weight of hydrocortisone were implemented into feed …

Molecular Characterization Of Leptin Gene In Sheep (Ovis Aries), Shahenda M. Hegazy, Mohamed Fouda, Ahmed Ateya, Huda A. El Emam

Mansoura Veterinary Medical Journal

INTRODUCTION: Advances in molecular genetic techniques have simplified the process of identifying individual differences at the DNA level. Genetic polymorphisms at candidate genes controlling economic features have recently drawn a lot of scholarly attention due to their potential as a tool for genetic selection and the identification of evolutionary linkages in livestock. OBJECTIVE: This work aimed to detect nucleotide sequence variants in Lep gene as genetic markers for growth and heat tolerance traits in Barki and Abudeleik sheep using PCR-DNA sequencing approach in search of single nucleotide polymorphisms (SNPs). METHODS: 30 female ewes, 15 of each breed (Barki and Aboudeleik) …

Artificial Intelligence And Its Use By Students In A Professional Program, Shirley P. O'Brien, Sara Brito, Steven Shisley

Pedagogicon Conference Proceedings

Artificial intelligence emerged as a blessing and a curse in higher education. An overview of the topic and how the presenters implemented and incorporated the Scholarship of Teaching and Learning into an assignment is highlighted. Student voice adds to the perspective enhancing engagement and learning, preparing students for future employment.

Post-Incarceration Drug Relapse Prevention In Penobscot County, Maine, Carolina Villalobos

Selected Social Change Portfolios in Prevention, Intervention, and Consultation

No abstract provided.

The Effects Of Nutritional Status On Patient Outcomes In The Surgical Intensive Care Unit, Whitt Harrelson, Brant Wagener, Andrew Barker

UAB Huntsville Research Day - All Presentations

2025 research poster

Tracheoesophageal Fistula Revision And Barriers To Care In Infant Asylee, Tina Huang, John Laue, Zaria Murrell

UAB Huntsville Research Day - All Presentations

No abstract provided.

One Million Platelets With An Interesting Twist, Hinal Rathi, Alina Sehar, Parekha Yedla, Farrah Ibrahim

UAB Huntsville Research Day - All Presentations

No abstract provided.

A Comprehensive Review On Nutritional Composition, Health Benefits, And Industrial Applications Of Jackfruit Seeds, Simran Dhani, Hamid, Nomali Ziphorah Ngobese, Sunny Sharma, Amit K. Jaiswal

Articles

Jackfruit (Artocarpus heterophyllus Lam.) is one of the undervalued fruits that is rich in many nutrients not only in the edible parts but also in generated waste such as the seed and peel. Seeds of jackfruit are usually considered as waste (15 %) but are rich in protein, starch as well as various bioactive compounds. Among the bioactive components, phenolics like catechin, ferulic acid, epicatechin, rutin, and gallic acid, are a few which possess many health-promoting properties. These bioactive compounds hold high antioxidant capacity and various pharmacological properties which lower the risk of various diseases by reducing free radical generation. …

Rotten Through The Cores: What Decomposition Can Tell Us About Carbon Cycling, Eileen C. Reeves

Dissertations, Master's Theses and Master's Reports

Sequestration of carbon (C) in forests means that the C is stored in the ecosystem and not emitted to the atmosphere, thus slowing the accumulation of greenhouse gases and mitigating the acceleration of manmade climate change. Quantifying the pools and fluxes of C in forests is therefore of considerable interest to landowners, policy makers, and scientists.

Decomposition is an ecological process central to the movement of C through ecosystems. This dissertation uses several techniques to help determine the factors influencing the speed of decomposition and long-term fate of decomposed plant material. In Chapter Two, phospholipid fatty acid analysis was used …

Examining The Role Of Plant Genome Size And Polyploidy In Shaping Arbuscular Mycorrhizal Fungi Symbioses, Abbigail J. Blackwell

Dissertations, Master's Theses and Master's Reports

Polyploid and larger genome size plants have been shown to contain more cellular nitrogen and phosphorus than related diploid and smaller genome size plants, indicating they have greater nutrient requirements. Given that arbuscular mycorrhizal fungi (AMF) associations can enhance plant nutrient acquisition, polyploid and larger genome size plants may form more associations with AMF to meet their increased nutrient demands and gain greater benefits from these symbioses. However, because AMF associations become unnecessary when nutrient-rich soils meet plant needs independently, these interactions may be more likely to occur under nutrient-poor conditions. For this research, we conducted two experiments to examine …

Ireland’S Best Kept Secret: The Unique Role Of Home Management Advisors In Supporting Families In The Community, Sonya Coffey, Amanda Mccloat, Elaine Mooney

Irish Journal of Applied Social Studies

In Ireland, early intervention family support models are the focus of researchers and policy makers. One such model, the Home Management Advisory (HMA) service, provided in the main by home economists, delivers education, support and advice to families on all aspects of home management. A qualitative examination of the role of home management advisors, underpinned by a strengths-based approach, was conducted through in depth semi-structured interviews with past and present advisors. The study aimed to gain insights into their experiences in delivering community-based family support. The study found service provision is limited to a small geographical area in the West …

Nutrition Curriculum Module 10 Celery Let's Get Cooking, Unm Prevention Research Center

Module 10 Nutrition Curriculum

No abstract provided.

Nutrition Curriculum Module 11 Raspberry Food Detectives, Unm Prevention Research Center

Module 11 Nutrition Curriculum

No abstract provided.

Nutrition Curriculum Module 11 Bean Food Detectives, Unm Prevention Research Center

Module 11 Nutrition Curriculum

No abstract provided.

Nutrition Curriculum Module 10 Celery Food Detectives, Unm Prevention Research Center

Module 10 Nutrition Curriculum

No abstract provided.

Nutrition Curriculum Module 12 Blueberry Food Detectives, Unm Prevention Research Center

Module 12 Nutrition Curriculum

No abstract provided.

Nutrition Curriculum Module 10 Celery Taste Testers, Unm Prevention Research Center

Module 10 Nutrition Curriculum

No abstract provided.

Nutrition Curriculum Module 12 Blueberry Let's Get Cooking, Unm Prevention Research Center

Module 12 Nutrition Curriculum

No abstract provided.