Open Access. Powered by Scholars. Published by Universities.®

Digital Commons Network™

Open Access. Powered by Scholars. Published by Universities.®

2025

Discipline
Institution
Keyword
Publication
Publication Type
File Type

Articles 7261 - 7290 of 10533

Full-Text Articles in Entire DC Network

Youtube User Traffic To Paired Epilepsy Education Videos In English And Spanish: Comparative Study., Luna Kimahri Varela, Stephanie Horton, Ahmed Abdelmoity, Jean-Baptist Lepichon, Mark A. Hoffman Mar 2025

Youtube User Traffic To Paired Epilepsy Education Videos In English And Spanish: Comparative Study., Luna Kimahri Varela, Stephanie Horton, Ahmed Abdelmoity, Jean-Baptist Lepichon, Mark A. Hoffman

Manuscripts, Articles, Book Chapters and Other Papers

BACKGROUND: Effectively managing epilepsy in children necessitates the active engagement of parents, a factor that is reliant on their understanding of this neurological disorder. Widely available, high-quality, patient-focused, bilingual videos describing topics important for managing epilepsy are limited. YouTube Analytics is a helpful resource for gaining insights into how users of differing backgrounds consume video content.

OBJECTIVE: This study analyzes traffic to paired educational videos of English and Spanish versions of the same content. By examining the use patterns and preferences of individuals seeking information in different languages, we gained valuable insights into how language influences the use of clinical …


Adverse Childhood Experiences In Early Adolescence And Adult Interpersonal Relationships Violence, Jenalee M. Dawson Mar 2025

Adverse Childhood Experiences In Early Adolescence And Adult Interpersonal Relationships Violence, Jenalee M. Dawson

Walden Dissertations and Doctoral Studies

Intimate partner violence (IPV) is a pervasive social issue that affects individuals and communities, often rooted in early life experiences such as adverse childhood experiences (ACEs). Understanding the link between ACEs and IPV is crucial for developing effective prevention and intervention strategies. This quantitative research explored the potential link between ACEs encountered during early adolescence and the subsequent occurrence of IPV in adult domestic relationships, building upon the foundational work of Felitti et al. Using a quantitative survey design, 30 participants aged 18 and older who had experienced at least one ACE were recruited via social media and surveyed. Bandura's …


Developing A Novel Index For Individual-Level Social Determinants And Cardiovascular Diseases In The Coronary Artery Risk Development In Young Adults (Cardia) Study, Tao Gao, Yinan Zheng, Brian Joyce, Lei Liu, Lili Liu, Catarina Kiefe, Sarah Forrester, Bing Yu, Ankeet Bhatt, Penny Gordon-Larsen, Donald Lloyd-Jones, Kai Zhang, Lifang Hou Mar 2025

Developing A Novel Index For Individual-Level Social Determinants And Cardiovascular Diseases In The Coronary Artery Risk Development In Young Adults (Cardia) Study, Tao Gao, Yinan Zheng, Brian Joyce, Lei Liu, Lili Liu, Catarina Kiefe, Sarah Forrester, Bing Yu, Ankeet Bhatt, Penny Gordon-Larsen, Donald Lloyd-Jones, Kai Zhang, Lifang Hou

Faculty, Staff and Student Publications

Background: Social determinants of health (SDH) have been found to contribute to cardiovascular risk and the development of cardiovascular disease (CVD). However, few studies have examined early-life exposure to SDH and the combined effect of multiple SDH measures on CVD. There is an urgent need to develop an SDH index for use in practice and clinical settings.

Methods: A total of 3189 participants from the CARDIA Study who had chest CT scans at the year-25 (Y25) visit were included in this study. Personal and parental SDH measures, including education, occupation, income, financial strain, and childhood family environment, were obtained through …


Spartan Daily, March 13, 2025, San Jose State University, School Of Journalism And Mass Communications Mar 2025

Spartan Daily, March 13, 2025, San Jose State University, School Of Journalism And Mass Communications

Spartan Daily, 2025

Volume 161, Issue 22


More Choosy For Minor Foods: Diet, Seasonality And Food Selection In Sympatric Frugivorous And Folivorous Lemurs, Mitchell Irwin, Vololonirina Rahalinarivo, Bruno Ramorasata, Jean-Luc Raharison, Jean-Freddy Ranaivoarisoa, Chloé Gherardi, Jessica Rothman Mar 2025

More Choosy For Minor Foods: Diet, Seasonality And Food Selection In Sympatric Frugivorous And Folivorous Lemurs, Mitchell Irwin, Vololonirina Rahalinarivo, Bruno Ramorasata, Jean-Luc Raharison, Jean-Freddy Ranaivoarisoa, Chloé Gherardi, Jessica Rothman

Faculty Articles, Papers, and Other Scholarship

Despite traditional dietary categories common in primatology (folivore, frugivore, insectivore), most primates use one or more food types beyond their primary one. Among lemurs, folivores tend to have a complicated, long gastrointestinal tract with an enlarged cecum, shearing teeth, and microbiome adaptations to foliage, while frugivores have simple teeth and guts and fast gut passage. Yet frugivores often eat some leaves, and folivores eat some fruit, and little is known about the selection rules they follow within each food type. We quantified diet and food chemistry for two sympatric rainforest lemurs: a cathemeral frugivore (brown lemur, Eulemur fulvus) and a …


The Current - Volume 35 Issue 10, Nova Southeastern University Mar 2025

The Current - Volume 35 Issue 10, Nova Southeastern University

Student Newspapers

No abstract provided.


Developing A Novel Index For Individual-Level Social Determinants And Cardiovascular Diseases In The Coronary Artery Risk Development In Young Adults (Cardia) Study, Tao Gao, Yinan Zheng, Brian Joyce, Lei Liu, Lili Liu, Catarina Kiefe, Sarah Forrester, Bing Yu, Ankeet Bhatt, Penny Gordon-Larsen, Donald Lloyd-Jones, Kai Zhang, Lifang Hou Mar 2025

Developing A Novel Index For Individual-Level Social Determinants And Cardiovascular Diseases In The Coronary Artery Risk Development In Young Adults (Cardia) Study, Tao Gao, Yinan Zheng, Brian Joyce, Lei Liu, Lili Liu, Catarina Kiefe, Sarah Forrester, Bing Yu, Ankeet Bhatt, Penny Gordon-Larsen, Donald Lloyd-Jones, Kai Zhang, Lifang Hou

2020-Current year OA Pubs

BACKGROUND: Social determinants of health (SDH) have been found to contribute to cardiovascular risk and the development of cardiovascular disease (CVD). However, few studies have examined early-life exposure to SDH and the combined effect of multiple SDH measures on CVD. There is an urgent need to develop an SDH index for use in practice and clinical settings.

METHODS: A total of 3189 participants from the CARDIA Study who had chest CT scans at the year-25 (Y25) visit were included in this study. Personal and parental SDH measures, including education, occupation, income, financial strain, and childhood family environment, were obtained through …


Spectator 2025-03-13, Editors Of The Spectator Mar 2025

Spectator 2025-03-13, Editors Of The Spectator

The Spectator

No abstract provided.


Analysis Of The Effect On N Nutrition On Dry Matter Yield Of A Sward By Reference To Potential Yield And Optimum N Content, G Lemaire, F Gastal, J Salette Mar 2025

Analysis Of The Effect On N Nutrition On Dry Matter Yield Of A Sward By Reference To Potential Yield And Optimum N Content, G Lemaire, F Gastal, J Salette

IGC Proceedings (1977-2023)

Previous work has shown that the N content of a sward could be related to the dry matter accumulation during the course of the regrowth by the following equation : N % = a(Wtb, where W is the weight of aboveground biomass and N % the N concentration of dry matter (Salette & Lemaire, 1981). The coefficient a represents the N % for an aerial biomass of I t/ha, and b characterizes the degree of dilution of N during the regrowth. When b = 0, N % remains constant during the regrowth. If b = I, there is an increase …


What Did Scotus Do To Wotus?, Hailey Rizzo Mar 2025

What Did Scotus Do To Wotus?, Hailey Rizzo

Ocean and Coastal Law Journal

The term “waters of the United States” has sparked half a century of debate among policymakers, judges, Supreme Court Justices, the Environmental Protection Agency, and the Army Corps of Engineers, culminating in the Supreme Court’s 2023 decision in Sackett v. Environmental Protection Agency. This Article chronicles the interpretive history of “waters of the United States” within the context of wetlands and discusses the broader implications of the Sackett decision on the nation’s water bodies.


Alimentation Minerale, Niveau Hydrique Et Utilization De L’Eau Par La Luzerne, Micheline Anneessens Mar 2025

Alimentation Minerale, Niveau Hydrique Et Utilization De L’Eau Par La Luzerne, Micheline Anneessens

IGC Proceedings (1977-2023)

L'eau est souvent un facteur limitant !es rendements puisque des problemes se posent au niveau de sa repartition dans l'es­pace et dans le temps. Aucune etude n'a encore montre comment dose et composi­tion d'engrais interagissent avec l'humidite du substrat sur ]'utilisation de l'eau par une plante fourragere forte consomma­trice de cette ressource.C'est dans ce but que le present essai a ete realise sur la luzerne.


Optimization Of Grassland Ecosystem Production By Anthropogenic Treatment, R Holubek, J Jancovic Mar 2025

Optimization Of Grassland Ecosystem Production By Anthropogenic Treatment, R Holubek, J Jancovic

IGC Proceedings (1977-2023)

Abundant amount of the new knowledge was gained by an intensive research of grassland ecosystem in Czechoslovakia and other European countries during last 25 years. It was con­firmed that under favourable humid conditions and sufficient macronutrients and micronutrients together with adequate N­fertilizing should be nearly reached ecologically conditioned level of potential productivity and dry matter or N-compounds yields should be increased by 100-200 or 200-300 per cent respectively (Velich, 1986). Introduction of scientific methods of controlled agricultural production together with higher landscape protection requirements, stability of ecosystems, quality and health­proved foods requirements have changed the traditional views to the nutrition …


Experiment Of Trace Elements Fertilizer Spraying On Sown Pasture, Tu Minyi Mar 2025

Experiment Of Trace Elements Fertilizer Spraying On Sown Pasture, Tu Minyi

IGC Proceedings (1977-2023)

The application of compound phosphate in the way of rot­ationary fertilizing in sections in successive years kept the vig­orous growth of pasture composed of perennial ryegrass (Lolium perenne) and white clover (Trifolium repens) in the first several years after the pasture was grazed in 1981. But the pas­ture could not keep the growing vigour even with the same level of fertilization in the last two years. Considering the unba­lanced nutrition being one of the major reasons, a preliminary experiment of trace elements spraying has been undertaken in Nanshan Sown Pasture-land aiming at identifying if trace fert­ilizers …


Some Nitrogen Forms And Micronutrients In Silage Maize Leaves As Affected By Nk Fertilization And Liming, C.L F. Carranca, M A. Castelo Branco Mar 2025

Some Nitrogen Forms And Micronutrients In Silage Maize Leaves As Affected By Nk Fertilization And Liming, C.L F. Carranca, M A. Castelo Branco

IGC Proceedings (1977-2023)

The nutritive value of a forage depends on the quality which, in time, is dependent on protein, sugar, cellulose, fat and min­eral elements content. The existence of deficiencies may limit the maximum yield and also the quality. Several experiments have been carried out in order to study the effect of liming and NK fertilization on the nutrients uptake by silage maize and yields.


The Diagnosis Of Grassland Mineral Nutrient Status Through Herbage Analysis, J Salette, Lydie Huche Mar 2025

The Diagnosis Of Grassland Mineral Nutrient Status Through Herbage Analysis, J Salette, Lydie Huche

IGC Proceedings (1977-2023)

It appears more and more clearly that soil analysis is not sufficient to give a good approximation of the mineral status of grassland soils. In perennial crops leaf analysis and empirical critical levels are widely utilized. This grassland approach emphasizes the good results which can be obtained for nitro­gen, potassium, phosphorus not from leaf but from the whole herbage plant analysis. This paper deals with pure grass stands.


Modelling Nutrient Uptake By A Grass Sward: Long Term Studies Over Several Years, J Salette, Lydie Huche Mar 2025

Modelling Nutrient Uptake By A Grass Sward: Long Term Studies Over Several Years, J Salette, Lydie Huche

IGC Proceedings (1977-2023)

Many experiments were conducted to assess the short term effects of fertilization management on nitrogen and mineral uptake of cut or grazed swards. One important work was performed to model the grass nutrition status during a regrowth (Salette, 1982; Salette et al., 1983; Salette et al., 1989), but for both a theoretical and practical point of view it is of great interest to evaluate the evolution of N and mineral uptake throughout all the years of a pasture life. This paper gives an analysis of nitrogen and mineral uptake dynamics during sev­eral years and proposes a model for sward N …


Influence Of Marching Band Experience On Eating Disorder Risk And Perceived Stress In Collegiate Marching Artists, Kalor Greve, Jaclyn B. Caccese, Matthew P. Brancaleone Mar 2025

Influence Of Marching Band Experience On Eating Disorder Risk And Perceived Stress In Collegiate Marching Artists, Kalor Greve, Jaclyn B. Caccese, Matthew P. Brancaleone

Journal of Sports Medicine and Allied Health Sciences: Official Journal of the Ohio Athletic Trainers Association

Introduction: Collegiate marching artists face severe and prevalent stressors that may contribute to poor mental health and unhealthy habits. The purpose of this study was to determine the effect of sex and years of participation in collegiate marching band on the relationship between eating disorder risk and perceived stress levels. Methods: Marching artists from an NCAA Division I university completed the Eating Disorder Questionnaire-6 (EDEQ-6) and Perceived Stress Scale (PSS-10) to obtain disordered eating behaviors and perceived stress levels, respectively. Spearman rank correlations were used to determine the relationship between PSS-10 scores and global and subscale EDEQ-6 scores, …


Pilliod V. Monsanto Company: Weeding Out Harmful Ingredients, Isabel Rickman Mar 2025

Pilliod V. Monsanto Company: Weeding Out Harmful Ingredients, Isabel Rickman

The Appendix, Journal of Health Care Law & Policy

No abstract provided.


Continuous Exposure To An Aversive Mixture: A Means Of Maintaining Aversion In Sheep Averted To Geigeria Ornativa O. Hoffm. (Vermeerbos) - An Assessment, Leendert D. Snyman Mar 2025

Continuous Exposure To An Aversive Mixture: A Means Of Maintaining Aversion In Sheep Averted To Geigeria Ornativa O. Hoffm. (Vermeerbos) - An Assessment, Leendert D. Snyman

Poisonous Plant Research (PPR)

Establishing aversion to Geigeria ornativa only lasts for some time, after which the induced aversion disappears and sheep start eating G. ornativa again. This behavior is aggravated by the social influence of non-averted sheep in mixed grazing situations. Exposing sheep continuously to a so-called “aversive mixture”, containing an aversive substance (lithium chloride) and the sensory characteristics of the plant (hexane extract of G. ornativa) mixed with a tasty meal (maize meal), following an initial aversion treatment, resulted in sustained aversion to G. ornativa in the field. This method proved to be applicable to mixed grazing situations with averted and …


Feasibility, Acceptability, And Satisfaction Of Redcap As A Tool For Interprofessional Education, Ross J. Bindler, Skye Mckennon, Connie M. Remsberg, Jennifer C. Miller, Marian Wilson Mar 2025

Feasibility, Acceptability, And Satisfaction Of Redcap As A Tool For Interprofessional Education, Ross J. Bindler, Skye Mckennon, Connie M. Remsberg, Jennifer C. Miller, Marian Wilson

Innovations in Health Sciences Education Journal

Interprofessional education (IPE) is an important component of health science training. Ensuring all students have access to necessary information prior to, during, and following simulation-enhanced IPE (Sim-IPE) activities is imperative to ensure a beneficial learning environment and student engagement. Ensuring access to necessary materials can be difficult due to differences in educational resources between institutions. This manuscript will assess the feasibility, acceptability, and satisfaction of using Research Electronic Data Capture (REDCap) as an educational tool for a Sim-IPE activity. After a pilot Sim-IPE activity, data from student evaluations was reviewed. Updates were made including use of REDCap as a universally …


The Bg News March 12, 2025, Bowling Green State University Mar 2025

The Bg News March 12, 2025, Bowling Green State University

BG News (Student Newspaper)

The BGSU campus student newspaper. March 12, 2025. Volume 104-Issue 20.


Effects Of Space Flight On Inflammasome Activation In The Brain Of Mice, Upal Roy, Roey Hadad, Angel A. Rodriguez, Alen Saju, Deepa Roy, Mario Gil, Robert W. Keane, Ryan T. Scott, Xiao W. Mao, Juan Pablo De Rivero Vaccari Mar 2025

Effects Of Space Flight On Inflammasome Activation In The Brain Of Mice, Upal Roy, Roey Hadad, Angel A. Rodriguez, Alen Saju, Deepa Roy, Mario Gil, Robert W. Keane, Ryan T. Scott, Xiao W. Mao, Juan Pablo De Rivero Vaccari

Health & Biomedical Sciences Faculty Publications

Space flight exposes astronauts to stressors that alter the immune response, rendering them vulnerable to infections and diseases. In this study, we aimed to determine the levels of inflammasome activation in the brains of mice that were housed in the International Space Station (ISS) for 37 days. C57BL/6 mice were launched to the ISS as part of NASA’s Rodent Research 1 Mission on SpaceX-4 CRS-4 Dragon cargo spacecraft from 21 September 2014 to 25 October 2014. Dissected mouse brains from that mission were analyzed by immunoblotting of inflammasome signaling proteins and Electrochemiluminescence Immunoassay (ECLIA) for inflammatory cytokine levels. Our data …


‘You're Panicking, I'M Panicking, Let's Do It Together!’ Special Educators' Views On Family Involvement During Covid-19, Diana L. Cruz, Tracy Gershwin, Guofeng Shen, Silvia Correa-Torres Mar 2025

‘You're Panicking, I'M Panicking, Let's Do It Together!’ Special Educators' Views On Family Involvement During Covid-19, Diana L. Cruz, Tracy Gershwin, Guofeng Shen, Silvia Correa-Torres

Journal of Educational Research and Innovation

Communication and family engagement in education shifted significantly during the COVID-19 pandemic. This qualitative study explored these changes by conducting ten focus groups with 43 PK-12 special educators from one school district, examining their experiences with family involvement during the first two years of the pandemic. Educators employed various innovative strategies to foster communication and maintain family involvement, including using technology, conducting home visits, offering open communication channels, and creating personal connections through interactive activities. Participants noted that decreased family involvement in the first year was primarily due to technological barriers, childcare challenges, and linguistic or communication differences. The study …


Do Cheaters Prosper? Effect Of Externally Supplied Momentum During Resistance Training On Measures Of Upper Body Muscle Hypertrophy, Francesca Augustin, Jeff Nippard, Alec Pinero, Alysson Enes, Adam Mohan, Max Sapuppo, Max Coleman, Milo Wolf, Patroklos Androulakis Korakakis, Paul Swinton, Brad Schoenfeld Mar 2025

Do Cheaters Prosper? Effect Of Externally Supplied Momentum During Resistance Training On Measures Of Upper Body Muscle Hypertrophy, Francesca Augustin, Jeff Nippard, Alec Pinero, Alysson Enes, Adam Mohan, Max Sapuppo, Max Coleman, Milo Wolf, Patroklos Androulakis Korakakis, Paul Swinton, Brad Schoenfeld

International Journal of Exercise Science

International Journal of Exercise Science 18(3): 329-342, 2025. Exercise technique, defined as the controlled execution of bodily movements to ensure an exercise effectively targets specific muscle groups while minimizing the risk of injury, is a resistance training (RT) variable frequently highlighted as critical to successful RT program outcomes, with proper technique suggested to play a role in maximizing muscle development. This study examined the effects of externally applied momentum on RT-induced muscular adaptations in the upper extremities. Thirty young adults were recruited to participate in a within-participant design, with one limb randomly allocated to perform biceps curls and triceps pushdowns …


Interlinkt.Org, Linking Internationals With Their New Homeland, A U.S. Refugee Resettlement Mobile Phone Website, Russell J. Chun Mar 2025

Interlinkt.Org, Linking Internationals With Their New Homeland, A U.S. Refugee Resettlement Mobile Phone Website, Russell J. Chun

Doctor of Leadership

Interlinkt.org is a mobile platform designed to enhance U.S. refugee resettlement by improving communication between newcomers, caseworkers, and churches. Grounded in Stephen Krashen's “Compelling Input Theory,” it aims to foster English language acquisition and cultural integration.

Key insights from the research include:

  1. A simple guide for volunteers assisting in refugee resettlement is needed.
  2. An unconscious communication barrier between caseworkers and volunteer groups due to privacy laws.
  3. Growing interest and use of Interlinkt by TESOL and ESL instructors in Texas and Colorado.

In 2024, over 100,024 refugees resettled in the U.S., many fleeing war and trauma. With limited formal support lasting …


No. 36: ‘Going To The Supermarket Was Hard’: Pandemic Foodscapes And Unsettled Food Practices Of Refugees In The Waterloo Region, Sujata Ramachandran, Elizabeth Onyango, Zhenzhong Si, Zack Ahmed, Mercedes Eguiguren, Jonathan Crush, Neil Arya Mar 2025

No. 36: ‘Going To The Supermarket Was Hard’: Pandemic Foodscapes And Unsettled Food Practices Of Refugees In The Waterloo Region, Sujata Ramachandran, Elizabeth Onyango, Zhenzhong Si, Zack Ahmed, Mercedes Eguiguren, Jonathan Crush, Neil Arya

Migration and Food Security (MiFOOD) Network

In this paper, we examine how the ‘new normal’ of pandemic-living transformed the local food environment in Ontario as pandemic foodscapes. Using selected findings from mixed methods research with a small sample of recently resettled refugees in the Waterloo region, we evaluated how these changes affected their grocery shopping and food-sourcing habits. We identify the distinctive ways the pandemic-related restrictions altered our participants’ interactions with their local food environment and influenced their food availability and accessibility. Our study found that participants spent more time acquiring food from a reduced number of food sources and experienced an overall weakening of their …


Gardner-Webb Alumnae Gain Respect In Strength And Conditioning Field Dominated By Men, Office Of University Communications Mar 2025

Gardner-Webb Alumnae Gain Respect In Strength And Conditioning Field Dominated By Men, Office Of University Communications

Gardner-Webb NewsCenter Archive

In a field dominated by men, four recent Gardner-Webb University alumnae are changing perceptions and gaining respect. As graduates of the Bachelor of Science in Exercise Science and Master of Science in Strength and Conditioning (S&C) programs at Gardner- Webb, they join the small percentage of women in America who are employed in top-level S&C jobs.


Academic Senate - Agenda, 3/11/2025, Academic Senate Mar 2025

Academic Senate - Agenda, 3/11/2025, Academic Senate

Academic Senate Agendas

No abstract provided.


Metabolic Signatures In Adipose Tissue Linking Lipophilic Persistent Organic Pollutant Mixtures To Blood Pressure Five Years After Bariatric Surgery Among Adolescents, Shudi Pan, Zhenjiang Li, Douglas I Walker, Brittney O Baumert, Hongxu Wang, Jesse A Goodrich, Sarah Rock, Thomas H Inge, Todd M Jenkins, Stephanie Sisley, Scott M Bartell, Stavra Xanthakos, Xiangping Lin, Brooklynn Mcneil, Anna R Robuck, Catherine E Mullins, Michele A La Merill, Erika Garcia, Max T Aung, Sandrah P Eckel, Rob Mcconnell, David V Conti, Justin R Ryder, Lida Chatzi Mar 2025

Metabolic Signatures In Adipose Tissue Linking Lipophilic Persistent Organic Pollutant Mixtures To Blood Pressure Five Years After Bariatric Surgery Among Adolescents, Shudi Pan, Zhenjiang Li, Douglas I Walker, Brittney O Baumert, Hongxu Wang, Jesse A Goodrich, Sarah Rock, Thomas H Inge, Todd M Jenkins, Stephanie Sisley, Scott M Bartell, Stavra Xanthakos, Xiangping Lin, Brooklynn Mcneil, Anna R Robuck, Catherine E Mullins, Michele A La Merill, Erika Garcia, Max T Aung, Sandrah P Eckel, Rob Mcconnell, David V Conti, Justin R Ryder, Lida Chatzi

Faculty, Staff and Students Publications

Persistent organic pollutants (POPs) are lipophilic environmental contaminants accumulated in the adipose tissue. Weight loss interventions, such as bariatric surgery, can mobilize POPs from adipose tissue into the bloodstream. We hypothesized that this mobilization could contribute to increases in blood pressure among 57 adolescents with severe obesity undergoing bariatric surgery. POPs and metabolic features were measured from visceral adipose tissue collected during surgery using gas and liquid chromatography, coupled with high-resolution mass spectrometry. Blood pressure was assessed at baseline, 6 months, and 5 years post-surgery. We used quantile g-computation to estimate associations of POP mixtures with blood pressure changes. With …


Simvastatin And Rifaximin In Decompensated Cirrhosis: A Randomized Clinical Trial, Elisa Pose, César Jiménez, Giacomo Zaccherini, Daniela Campion, Salvatore Piano, Frank Erhard Uschner, Koos De Wit, Olivier Roux, Kohilan Gananandan, Wim Laleman, Cristina Solé, Sonia Alonso, Berta Cuyàs, Xavier Ariza, Adrià Juanola, Ann T Ma, Laura Napoleone, Jordi Gratacós-Ginès, Marta Tonon, Enrico Pompili, Jordi Sánchez-Delgado, Andrew S Allegretti, Manuel Morales-Ruiz, Marta Carol, Martina Pérez-Guasch, Núria Fabrellas, Judit Pich, Claudia Martell, María Joyera, Gemma Domenech, José Ríos, Ferrán Torres, Miquel Serra-Burriel, Rubén Hernáez, Elsa Solà, Isabel Graupera, Hugh Watson, Germán Soriano, Rafael Bañares, Rajeshwar P Mookerjee, Claire Francoz, Ulrich Beuers, Jonel Trebicka, Paolo Angeli, Carlo Alessandria, Paolo Caraceni, Víctor M Vargas, Juan G Abraldes, Patrick S Kamath, Pere Ginès Mar 2025

Simvastatin And Rifaximin In Decompensated Cirrhosis: A Randomized Clinical Trial, Elisa Pose, César Jiménez, Giacomo Zaccherini, Daniela Campion, Salvatore Piano, Frank Erhard Uschner, Koos De Wit, Olivier Roux, Kohilan Gananandan, Wim Laleman, Cristina Solé, Sonia Alonso, Berta Cuyàs, Xavier Ariza, Adrià Juanola, Ann T Ma, Laura Napoleone, Jordi Gratacós-Ginès, Marta Tonon, Enrico Pompili, Jordi Sánchez-Delgado, Andrew S Allegretti, Manuel Morales-Ruiz, Marta Carol, Martina Pérez-Guasch, Núria Fabrellas, Judit Pich, Claudia Martell, María Joyera, Gemma Domenech, José Ríos, Ferrán Torres, Miquel Serra-Burriel, Rubén Hernáez, Elsa Solà, Isabel Graupera, Hugh Watson, Germán Soriano, Rafael Bañares, Rajeshwar P Mookerjee, Claire Francoz, Ulrich Beuers, Jonel Trebicka, Paolo Angeli, Carlo Alessandria, Paolo Caraceni, Víctor M Vargas, Juan G Abraldes, Patrick S Kamath, Pere Ginès

Faculty, Staff and Students Publications

Importance: There are no useful treatments to prevent the development of severe complications of liver cirrhosis. Simvastatin and rifaximin have shown beneficial effects in liver cirrhosis.

Objective: To assess whether simvastatin combined with rifaximin improves outcomes in patients with decompensated cirrhosis.

Design, setting, and participants: Double-blind, placebo-controlled, phase 3 trial conducted among patients with decompensated cirrhosis in 14 European hospitals between January 2019 and December 2022. The last date of follow-up was December 2022.

Interventions: Patients were randomly assigned to receive simvastatin, 20 mg/d, plus rifaximin, 1200 mg/d (n = 117), or identical-appearing placebo (n = 120) for 12 months …