Digital Commons Network^™

A Comprehensive Diabetes Symptom Management Program For Independent Living Facilities, Brooke A. Foster, Mary Jan Greer

Spring 2025 OTD Capstone Symposium

This project aimed to support older adults with diabetes mellitus (DM) and pre-diabetes in independent living facilities through a comprehensive symptom management program. Implemented at Coastal Heights Senior Living in Costa Mesa, California, the program focused on improving overall education and self-management of DM symptoms, emphasizing foot care, physical activity, and nutrition. Using a client-centered approach and the Person-Occupation-Environment-Performance model, participants engaged in group and individual sessions over an eight-week period. Outcomes showed an increased understanding of DM, improved self-care behaviors, and enhanced ability to manage symptoms independently, supporting aging in place and promoting overall wellness.

Heredity, Chris Burley, Lisa K. Lashley, Charles J. Golden

Essays in Developmental Psychology

Heredity is the sum of biological processes that result in the transmission of genetic traits from parents to their offspring, making each individual unique. Through the transmission of genetic traits, heredity is responsible for each individual’s genotype, as well as his or her phenotype. The genes that are passed down from generation to generation have a considerable influence on psychological characteristics including intelligence, personality, mental health, and patterns of behavior. However, when considering psychological characteristics passed down through heredity, it is vital that environmental aspects are also considered.

All Stressed Out: An Investigation On The Effects Of Environmental Stressors On The Northern Leopard Frog (Rana Pipiens), Ella C. Wittmuss

Honors Thesis

Corticosterone (CORT) is the primary glucocorticoid in many vertebrates, including mammals, birds, reptiles, and amphibians. When an organism is exposed to external or internal stressors, CORT levels often increase (Rich & Romero, 2005; Titon et al., 2021). An increase in CORT can cause adverse physiological effects such as slower growth, malformations in different parts of the body, and specific blood sugar diseases such as diabetes (Glennemeier & Denver, 2002; Tarlow &Blumstein, 2007). CORT levels are indicators of survival, growth, and reproduction in larval amphibians. Many species, including our model organism, the Northern Leopard Frog (Rana pipiens), are often subjected to …

Developmental Disabilities, Christopher N. Tirado, Lisa K. Lashley, Charles J. Golden

Essays in Developmental Psychology

According to the Center for Disease Control and Prevention (CDC), “developmental disabilities are a group of conditions due to an impairment in physical, learning, language, or behavior areas.” The CDC estimates that approximately one in six children aged 3 through 17 in the United States have one or more developmental disabilities, as well as, other developmental delays (Boyle, et al., 2011). The term developmental disability is associated with the conditions of attention deficit hyperactivity disorder (ADHD), autism spectrum disorder, cerebral palsy, hearing loss, intellectual disability, learning disabilities, epilepsy, cerebral palsy, vision impairment, and other associated developmental delays.

Spectrum Of Congenital Anomalies Detected Through Anatomy Ultrasound At A Referral Hospital In Ghana, Alim Swarray-Deen, Morgan Yapundich, Sarah Boudova, Kwaku Doffour-Dapaah, Jeff Osei-Agyapong, Perez Sepenu, Alex K. Boateng, Teresa A. Mensah, Patrick Anum, Nana Essuman Oduro, Theophilus Adu-Bredu, Promise E. Sefogah, Jerry Coleman, Samuel A. Oppong

Department of Obstetrics and Gynecology Faculty Papers

BACKGROUND: Africa has a high burden of congenital anomalies due in part to limited preconception care, infections, and environmental exposures. However, the true prevalence of congenital anomalies is unclear because of insufficient access to prenatal diagnostic services. We aimed to determine the rate of congenital anomalies, and characterize the anomalies detected prenatally at a referral hospital in Ghana.

METHODS: We performed a four-year retrospective review of all fetal anomaly ultrasounds performed and congenital anomalies detected from January 1st, 2020, to December 31st, 2023, at Korle Bu Teaching Hospital, Accra, Ghana. Data were extracted from the electronic database on maternal age, …

Midlife Physical Changes, Kirsten Horne, Lisa K. Lashley, Charles J. Golden

Essays in Developmental Psychology

Aging occurs at different rates in individuals. These rates are influenced by factors including genetics, lifestyle, and health. Midlife is considered to be the central period of one’s life, consisting of individuals who are approximately 45 to 65 years of age, although some researchers suggest midlife consists of individuals who are 40 to 65 years of age. There are a variety of changes that occur throughout life. However, a majority of the changes that occur during midlife are considered to be normative physical changes. The physical changes in midlife include but are not limited to changes in appearance, senses, muscles, …

Comparing Out-Of-Pocket Costs And Health-Related Quality Of Life Between Sodium-Glucose Cotransporter 2 Inhibitors And Glucagon-Like Peptide-1 Receptor Agonists In Patients With Type 2 Diabetes, Sisi Hu, Preeti P. Zanwar, Tara Jenkins, Rajkumar J. Sevak, Bhaskara R. Jasti

Pacific Faculty Work

Purpose: To compare the impact of sodium-glucose cotransporter 2 inhibitor (SGLT2 inhibitor), glucagon-like peptide-1 receptor agonist (GLP-1 RA), with or without metformin, on out of pocket and total prescription expenditure and health-related quality of life (HRQoL) for patients with type 2 diabetes mellitus (T2DM). Patients and Methods: This observational study utilized 2017– 2021 Medical Expenditure Panel Survey (MEPS) data from patients with T2DM (≥ 18 years) on SGLT2 inhibitor, GLP-1 RA, with or without metformin, from payer and self-perspective. HRQoL was assessed using physical (PCS) and mental component summary (MCS) scores based on Veterans Rand 12. This study estimated survey-weighed …

Prooxidant Effect Of Uric Acid On Human Leukocytic Dna: An In Vitro And Ex Vivo Study, Yim Tong Savio Szeto, Vincy Sze Wing Li, Yuen Lam Pon

Turkish Journal of Biology

Background/aim: Uric acid is a major contributor to the total antioxidant capacity of human plasma. However, this endogenous substance’s antioxidant and prooxidant properties have not yet been reported.

Conclusion: In this study, the comet assay was employed in vitro to determine the effect of uric acid on DNA damage in human lymphocytes and leukocytic DNA damage in hyperuricemia patients with and without renal failure.

Results: DNA damage in lymphocytes occurred at uric acid concentrations of ≥600 μM. Adding catalase to the uric acid solution diminished the damaging effect, indicating that hydrogen peroxide mediated the prooxidant activity. Moreover, …

Resveratrol Modulates Triosephosphate Isomerase And Mineralization In Osteosarcoma Cells: Potential Target For Novel Therapeutic Strategies, Gonca Tuna, Si̇bel Çinar Asa, Eli̇f Ertürk, Yaren Yildiz, Ferda Ari

Turkish Journal of Biology

Background/aim: Osteosarcoma, a primary malignant bone tumor, is challenging to treat due to its aggressive nature and limited therapies. Resveratrol (RES), a natural polyphenol, has potential anticancer properties. Hence, we investigated RES’s impact on osteosarcoma cells, focusing on triosephosphate isomerase (TPI) and related mechanisms.

Materials and methods: RES was applied to osteosarcoma (SaOS-2) and healthy fetal osteoblast (hFOB 1.19) cells for 48 h, and cell viability was measured by SRB assay. The mode of cell death was examined using Hoechst 33342/annexin V/propidium iodide. TPI and methylglyoxal (MG) enzyme levels were determined by ELISA. The effect of RES on …

Caregivers’ Satisfaction With And Perceived Cultural Sensitivity Of A Modification Of A Child Injury Prevention Program For Spanish-Speaking Families, Karen Padilla

Honors Theses

Unintentional injuries are a leading cause of death among children in the United States. Caregivers play a critical role in reducing children’s risk of injury by adopting appropriate supervision behaviors and engaging in safety-proofing practices. The Supervising for Home Safety (SHS) program is a video-based intervention developed to increase caregiver supervision for children ages 2–5 by targeting beliefs about injury vulnerability, injury preventability, and self-efficacy for implementing safety precautions. While SHS has demonstrated effectiveness in English-speaking populations, no research has examined its adaptation and impact among Spanish-speaking caregivers. This study aimed to examine caregivers perceived cultural sensitivity and satisfaction with …

Attachment Theory: John Dollard And Neal Miller, Carla Cabrera, Lisa K. Lashley, Charles J. Golden

Essays in Developmental Psychology

No abstract provided.

Bio-Physiological Development During Adulthood, Maria Boix Braga, Charles J. Golden, Lisa K. Lashley

Essays in Developmental Psychology

Defining adulthood, and what the criteria truly is to be able to consider oneself an adult, varies from culture to culture. Biologically, adulthood can also be defined as the period in which full physical and intellectual maturity has been attained. It is a period that is defined slightly differently depending on the source, but it is agreed that it tends to be considered the life period between ages 18 and 60. However, the definition of adulthood can have varying legal and sociocultural factors as well. For example, the legal definition of an adult is a person who has reached the …

Parental Influence, Justin Burgess, Lisa K. Lashley, Charles J. Golden

Essays in Developmental Psychology

An adequate level of parenting—providing enough nutrition, shelter, exposure to language and peers, or not harshly punishing children (punching, kicking, striking with a weapon)—seems to not have a long-term effect on cognitive development in children. Twin and adoption studies have found that intelligence is accounted for almost entirely by genes and nonshared environment, which includes peers, teachers, and unique experiences. However, there are parenting styles and types of home environments that are correlated with better school performance, stronger school engagement, and more words spoken at certain ages.

Nutrition And Growth, Chris Burley, Lisa K. Lashley, Charles J. Golden

Essays in Developmental Psychology

From a child’s embryonic development in the womb to adulthood, nutrition plays a key role in physical, mental, and social growth and development. Throughout the lifespan, proper nutrition and growth are essential to living a long, healthy life. Nutrition is particularly important in the developmental period.

Harry Harlow’S Nature Of Love (1958), Jonathan B. Santo

Essays in Developmental Psychology

In Harold Harlow’s 1958 address of the American Psychological Association, he hoped to tackle a concept he felt was too often avoided by the psychologists of his time, the nature of love. His work on the behavior of macaques when reared without their mothers makes a compelling argument about the limits of viewing psychology (and by extension development) as simply the reduction of “primary drives” like hunger, thirst and avoidance of pain.

Quality Improvement Project Improving Tele-Sitter Usage In The Surgical Trauma Pcu, Stephanie Stone

Doctor of Nursing Practice Projects

This project aimed to improve the knowledge and usage of virtual patient sitters/tele-sitters for surgical trauma progressive care nurses in the surgical trauma progressive care unit through the implementation of nursing education, utilizing evidenced based teaching strategies. Nurse leaders identified a need for staff education among the surgical trauma registered nurse staff population. The goal of the project was to increase knowledge of virtual patient sitters/tele-sitters and how to order them, improve the understanding of the benefits of utilizing the device and to increase the overall usage of the devices on the surgical trauma progressive care unit patients that would …

Early Stages Of Sociocultural Development, Lisa L. Persinger, Joey D. Persinger

Essays in Developmental Psychology

We often think about the development of a person’s interpersonal skills, relationships, and identity as something that happens after birth, and certainly, it does. However, in practice, prenatal (before birth) interactions between caregivers and the fetus start the sociocultural developmental process that continues after a baby is born. Personality development, interpersonal style, and identity begin before birth and extend far into the life span. Caregivers provide interactions as well as physical care during pregnancy, and after birth, that influence these developments. This chapter will provide an overview of how interactions from conception through age two influence trust and attachment, emotional …

Environmental Teratogens, Ashley R. Strong, Lisa K. Lashley, Charles J. Golden

Essays in Developmental Psychology

Environmental teratogens are external agents that can increase the risk for carcinogenesis, malformations, mutagenesis, or deficient growth in an embryo or fetus. There are two general categories of teratogenic agents, which include errors in genetic processing, and environmental agents or factors. Both genetic and environmental teratogens can lead to embryopathology, but they have different pathologic processes. Errors in genetic processing can lead to abnormal development via gene abnormalities, chromosome deletion, chromosome excess, or chromosome rearrangement. Environmental teratogens, on the other hand, interact with the embryo during development, which can lead to congenital malformations and a multitude of other deficits. Environmental …

Ali Ibn Sahl Rabban Al-Tabari, Mithra H. Pirooz, Jonathan B. Santo

Essays in Developmental Psychology

Abu al-Hasan Ali ibn Sahl Rabban al-Tabari was born to a Persian family in current-day Turkmenistan, but later moved to what is now Northern Iran. Born circa 838 CE, he died around 870 CE. A Muslim hakim (wise man), he is known for his contributions to the field of medicine and psychology. As a teacher, his legacy continued with his student, Muhammad ibn Zakarīya Rāzi ("Rhazes").

Effects Of Enzyme Treatment Combined With Monascus Solid-State Fermentation On Chemical Composition Of Poria Cocos, Peng Cancan, Liu Tao, Deng Junjie, Zhou Bo

Food and Machinery

［Objective］ To improve the utilization of Poria cocos resources.［Methods］ This paper employs cellulase and xylanase in combination with Monascus for the solid -state fermentation of Poria cocos,and measures the changes in the content of alkali -soluble polysaccharides,water -soluble polysaccharides,β-glucans,reducing sugars,total triterpenes,pachymic acid,and Monacolin K in fermentation products.［Results］］ Compared with the other five strains of Monascus,Monascus purpureus 250 Gy has more significant changes in the chemical composition of Poria cocos,among which the content of water -soluble polysaccharides reaches 61.99 mg/g after 6 days of fermentation by Monascus purpureus 250 Gy,which is 1.58 times higher than that of raw Poria cocos.Compared with …

Design Of Online Inspection Device For Wheat Processing Grain Size Based On Dynamic Image, Wang Mingxu, Zhao Haojun, Yang Lei, Wu Junyong, Wu Runze

Food and Machinery

［Objective］ To address the prominent issues of delayed feedback and low detection efficiency in the offline particle size distribution detection of traditional wheat processing.［Methods］ The dynamic image method was applied to particle size detection in the wheat processing process.An online particle size detection device was designed based on wheat processing technology,including the design of key structures and algorithm software.The device was compared and analyzed with the manual sieving method for sample materials.［Results］］ Compared with the sieving method and laser method,the maximum relative errors in the detection results of the device for the I and II skin grinding materials were no …

Effects Of Five Different Processing Methods On Functional Components , In Vitro Antioxidant Ability , And Antibacterial Activities Of Penthorum Chinense Pursh, Liang Hongchun, Xia Chen, Deng Junlin, Yu Manyou, Liu Gang, Xiang Zhuoya

Food and Machinery

［Objective］ To elucidate the effects of processing methods on the components and functions of Penthorum chinense Pursh,and to provide a theoretical foundation for the development of new products.［Methods］ This study compares the effects of five distinct processing methods -cleansing,wine -processing,vinegar -processing,salt-processing,and ginger -processing -on the functional components,in vitro antioxidant activity,and antibacterial activity of Penthorum chinense Pursh.To be specific,the differences in functional components before and after processing are analyzed,the in vitro antioxidant activity is measured using DPPH and ABTS＋ radical scavenging models,and the antibacterial effects of the processed medicine against Escherichia coli,Staphylococcus aureus,Salmonella paratyphi B,and 向卓亚（1994—），女，四川省农业科学院农产品加工研究所 （四川省农业科学院食物与营养健康研究所 ）助理研究员，硕士。E-mail：2462526735 @qq.com引用格式：梁红春，夏陈，邓俊琳，等.5种处理方法对赶黄草功效成分、体外抗氧化性和抑菌活性的影响 ［J］.食品与机械，2025，41（3）：134-141.C itation:LIANG …

Study On The Purification Process Of Flavonoids From Phallus Impudicus And Its Effect On Exercise Endurance In Mice, Bian Wenkun

Food and Machinery

［Objective］ This study aimed to optimize the purification process of flavonoids from Phallus impudicus and explore its anti -fatigue effect,and develop potential anti -fatigue products.［Methods］ The purification process of flavonoids from P.impudicus was optimized using single factor and response surface methodology,and the effect of purified flavonoids from P.impudicus on exercise endurance in mice was studied.［Results］］ Compared with AB -8,HP-20,and D 101,the PVPP had the highest adsorption rate for flavonoids from P.impudicus,and the optimal purification process was as follows:the concentration of crude extract of flavonoids from P.impudicus was 3.2 g/L,the concentration of ethanol elution solution was 56%,the elution flow rate was …

Purification Of Polyphenols From Distiller's Grains And Its Antioxidant Activity In Vitro, Yan Junling, Zheng Jia, Zhang Weijian, Li Mao, Zhao Jiawei, Qin Fengyang

Food and Machinery

［Objective］ To purify and enrich the distiller's grain polyphenols (DGPs ) with good antioxidant activity.［Methods］ Organic solvent extraction combined with macroporous adsorption resin was used to enrich and recover DGPs from the distiller's grains deep eutectic solvent (DES ) extraction solution.The purity and antioxidant activity of the purified products were determined.Extraction solvents and resin types were screened,and adsorption kinetics,isotherms,and thermodynamics were used to explain the adsorption mechanism.The optimal process conditions were determined.The in vitro antioxidant activity of the polyphenols was evaluated by measuring their ability to scavenge 1,1-diphenyl -2-trinitrophenylhydrazine (DPPH ) free radicals and 2,2'-azino -bis(3-ethylbenzothiazoline -6-sulfonic acid ) diammonium …

Purification Process And Antioxidant Activity In Vitro Of Polysaccharides From Safflower, Zhang Xinxin, Wang Fuling

Food and Machinery

［Objective］ This study aimed to extract Safflower polysaccharides (SPS) via water extraction and alcohol precipitation method,and to analyze their structural characteristics and antioxidant activity in vitro.［Methods］ SPS was separated into three fractions -SPS-A,SPS-B and SPS -C using DEAE -52 ion exchange and Sephadex G -200 gel chromatography.Structural properties were analyzed through UV -vis scanning and infrared spectroscopy.The antioxidant activity of SPS -A was assessed through DPPH radical scavenging and ferric reducing antioxidant power (FRAP ) assays.［Results］］ The polysaccharide contents of SPS -A,SPS -B and SPS -C was 89.75%,90.37%,90.22%,respectively.The samples did not contain protein or nucleic acid substances.It is speculated that …

Effects Of Five Drying Methods On The Drying Characteristics And Quality Of Peanuts, Xie Yongkang, Wang Xi, Ju Haoyu, Wang Weina, Wang Xiaodong

Food and Machinery

［Objective］ To determine the appropriate mechanical drying technology for peanuts.［Methods］ Fresh peanuts were used as raw materials.The effects of heat pump drying (HPD ),far infrared drying (FID),electric heating drying (EHD ),far infrared combined heat pump drying (FI-HPD ),and natural drying (ND) on drying time,unit energy consumption,drying rate,nutritional quality,color,texture,and germination rate were compared and analyzed.［Results］］ During the four mechanical drying methods,the moisture ratio and drying rate of peanuts decreased with the prolongation of drying time,and the drying process was a falling -rate drying phase.Among these,the FI -HPD group had the shortest drying time and the lowest unit energy consumption.The drying method …

Research Progress On Microbial Inactivation In Food Induced By Magnetic Fields, Xiao Jin, Yang Na, Zheng Panxi, Xu Xueming, Yang Ruijin

Food and Machinery

As a novel non -thermal sterilization technology,the magnetic field has attracted much attention due to its strong penetrability and green and safe characteristics.Oscillating magnetic fields can effectively eliminate microorganisms and prolong the shelf life of food while maintaining the nutritional properties of food,and static magnetic fields have also shown great potential in inhibiting the growth of microorganisms in food.However,the mechanisms of inhibition and inactivation of microorganisms in food by different types of magnetic fields have not been systematically elaborated and analyzed.Therefore,this paper reviews the research progress of magnetic fields in eliminating and inhibiting microorganisms in food,encompassing the perspectives of mechanisms …

Research Progress On Oleogel Preparation And Application In Food, Qu Yanfeng, Liu Ruoming, Kong Zhen, Pei Runan, Zhang Xiaohong

Food and Machinery

As one of the widely recognized semi -solid plastic fat substitutes,oleogel can be used to replace food products,such as margarine and shortening oil,that contain high levels of saturated fatty acids (SFAs ) and trans fatty acids (TFAs ).This paper illustrates four methods for oleogel preparation,including direct dispersion.Besides,the paper presents the characteristics of various gelling agents for oleogels,along with the research status and progress of oleogel application in the food industry.Finally,this paper puts forward prospective outlooks for oleogel applications in food.

Cottonseed Polyol-Based Composite Evaluated With Inorganic Fillers, Kehinde Esther Ayodeji

Electronic Theses & Dissertations

Composites are extensively utilized as raw materials in an industry. In this study, we synthesized polymer composites, cottonseed oil polyol-based composites, incorporating inorganic fillers. This synthesis process involves the epoxidation of cottonseed oil followed by ring opening. Various characteristics of the polyol, such as the presence and quantity of hydroxyl groups (-OH), iodine value, and viscosity, and Fourier transform infrared spectroscopy (FTIR) was determined. The composite samples were prepared by mixing different fillers (SiO₂, TiO₂, and Al₂O₃). These composite formulations underwent three-week processing period, with each filler being incorporated at room temperature. …

Distinct Adipose Progenitor Cells Emerging With Age Drive Active Adipogenesis, Guan Wang, Gaoyan Li, Anying Song, Yutian Zhao, Jiayu Yu, Yifan Wang, Wenting Dai, Martha Salas, Hanjun Qin, Leonard Medrano, Joan Dow, Aimin Li, Brian Armstrong, Patrick T Fueger, Hua Yu, Yi Zhu, Mengle Shao, Xiwei Wu, Lei Jiang, Judith Campisi, Xia Yang, Qiong A Wang

Children’s Nutrition Research Center Staff Publications

Starting at middle age, adults often suffer from visceral adiposity and associated adverse metabolic disorders. Lineage tracing in mice revealed that adipose progenitor cells (APCs) in visceral fat undergo extensive adipogenesis during middle age. Thus, despite the low turnover rate of adipocytes in young adults, adipogenesis is unlocked during middle age. Transplantations quantitatively showed that APCs in middle-aged mice exhibited high adipogenic capacity cell-autonomously. Single-cell RNA sequencing identified a distinct APC population, the committed preadipocyte, age-enriched (CP-A), emerging at this age. CP-As demonstrated elevated proliferation and adipogenesis activity. Pharmacological and genetic manipulations indicated that leukemia inhibitory factor receptor signaling was …