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2025

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Articles 1981 - 2010 of 10512

Full-Text Articles in Entire DC Network

Adipose Tissue Estrogen Receptor-Alpha Overexpression Ameliorates High-Fat Diet–Induced Adipose Tissue Inflammation, Marion C. Hope, Christian A. Unger, M Chase Kettering, Cassidy E. Socia, Ahmed K. Aladhami, Barton C. Rice, Darya S. Niamira, Ben P. Wiznitzer, Diego Altomare Ph.D., William E. Cotham, Reilly T. Enos Oct 2025

Adipose Tissue Estrogen Receptor-Alpha Overexpression Ameliorates High-Fat Diet–Induced Adipose Tissue Inflammation, Marion C. Hope, Christian A. Unger, M Chase Kettering, Cassidy E. Socia, Ahmed K. Aladhami, Barton C. Rice, Darya S. Niamira, Ben P. Wiznitzer, Diego Altomare Ph.D., William E. Cotham, Reilly T. Enos

Faculty Publications

Context

We created an innovative mouse model that enables inducible overexpression of estrogen receptor-alpha (ERα), specifically in adipose tissue (Adipo-ERα↑). Objective

We aimed to investigate how elevated Adipo-ERα↑ influences the development of high-fat diet (HFD)-induced obesity in both male and female mice. Methods

Male and female Adipo-ERα↑ mice and littermate controls were fed a low-fat diet (LFD) or HFD for 13 weeks. Adipo-ERα↑ was induced at the initiation of dietary treatment. Body morphology and composition, hepatic lipid accumulation, glucose tolerance, fasting insulin concentrations, and adipose tissue mRNA profiling were assessed. Liquid chromatography–mass spectrometry was used to determine circulating and adipose …


A Scoping Review Of Oral Feeding Skill Development In Typically Developing Children Part Ii: Exploring Variability In Oral Feeding Skill Descriptions, Amy Delaney, Anna Flatt, Hannah Koepp, Alissa Fial, Katherine C. Hustad Oct 2025

A Scoping Review Of Oral Feeding Skill Development In Typically Developing Children Part Ii: Exploring Variability In Oral Feeding Skill Descriptions, Amy Delaney, Anna Flatt, Hannah Koepp, Alissa Fial, Katherine C. Hustad

Speech Pathology and Audiology Faculty Research and Publications

Purpose:

This scoping review is the second in a two-part series that aims to synthesize the literature on oral feeding skills development and to create a classification system of observable skills. Building on the findings from Part 1, this article compiles and analyzes the types of feeding skills reported across studies and proposes a framework for standardizing terminology.

Method:

The review followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews guidelines. Of the 14 studies identified in Part 1 that focused on feeding skill development, 11 included unique skill descriptions. These skills were coded and …


Adipokines Mediate Fat-To-Ovary Communication To Regulate Oogenesis, Adipocyte Size, And Lipid Storage In Drosophila Melanogaster, Chad Herbert Simmons Oct 2025

Adipokines Mediate Fat-To-Ovary Communication To Regulate Oogenesis, Adipocyte Size, And Lipid Storage In Drosophila Melanogaster, Chad Herbert Simmons

Theses and Dissertations

Humans have complex signaling pathways that allow them to store and expend energy based on nutritional quality and availability. Inter-organ signaling is used to communicate nutrient availability between organs based on nutritional needs and the rate of cellular division. Our main overarching question is to investigate how fat-derived signals affect adipocyte morphology and the maintenance of stem cells in the ovary. While signaling pathways, like insulin and mTOR, and some adipokines that are involved in inter-organ nutrient sensing have been identified, the exact nutrient reliant mechanisms of stem cell maintenance are not completely understood. Using Drosophila melanogaster as a model, …


Approaches To Reduce The Impact Of Stroke In Gulf Cooperation Council Nations, Muath A. Alammar Oct 2025

Approaches To Reduce The Impact Of Stroke In Gulf Cooperation Council Nations, Muath A. Alammar

Saudi Medical Journal

No abstract provided.


Phase Iv Clinical Trials For The Treatment Of Non-Small Cell Lung Carcinoma (Nsclc): A Systemic Review From 2020-2025, Yousif A. Kariri, Mohammed H. Alqasmi, Bijad S. Alqahtani Oct 2025

Phase Iv Clinical Trials For The Treatment Of Non-Small Cell Lung Carcinoma (Nsclc): A Systemic Review From 2020-2025, Yousif A. Kariri, Mohammed H. Alqasmi, Bijad S. Alqahtani

Saudi Medical Journal

ABSTRACT Objective: To evaluate and provide evidence on drugs investigated in completed phase IV clinical trials for adult non-small cell lung carcinoma (NSCLC) therapy, primarily focusing on treatment objectives and adverse effects. Methods: Clinical research studies from January 2020 to January 2025 were systematically reviewed using the “ClinicalTrials.gov” database. The inclusion criteria focused on publicly available, relevant, and completed Phase IV studies limited to “Clinicaltrials.gov”, while those not meeting these specifications were excluded. As of 3 January 2025, a total of 7,541 Phase IV clinical trials were available on “ClinicalTrials.gov”, of which 121 were related to NSCLC. Results: Six of …


Stroke Incidence, Mortality And Disability-Adjusted Life Years (Dalys) Trends In Association With Air Pollution, Dietary And Metabolic Risk Factors In Gulf Cooperation Council Countries: Global Burden Of Disease Data Based Analysis 1990-2021, Bandar N. Aljafen, Anusha S. Meo, N. Shaikh, Sultan A. Meo Oct 2025

Stroke Incidence, Mortality And Disability-Adjusted Life Years (Dalys) Trends In Association With Air Pollution, Dietary And Metabolic Risk Factors In Gulf Cooperation Council Countries: Global Burden Of Disease Data Based Analysis 1990-2021, Bandar N. Aljafen, Anusha S. Meo, N. Shaikh, Sultan A. Meo

Saudi Medical Journal

ABSTRACT Objectives: To identify the primary risk factors contributing to stroke incidents and deaths, analyzing the trends and changes in regional stroke statistics between 1990 and 2021 in the Gulf Cooperation Council (GCC) countries. Methods: This longitudinal time trend study was conducted in the Department of Physiology, College of Medicine, King Saud University, Riyadh, Saudi Arabia, from June to August 2024. The data were recorded from the Institute for Health Metrics and Evaluation (IHME) and the Global Burden of Diseases (GBD) datasets. The incidence, mortality, and disability-adjusted life year (DALY) rates of stroke in the GCC countries, Bahrain, Kuwait, Oman, …


Characterization And Management Of Pain Across Phases Of Intraosseous Infusion In Emergency Department Patients With Non-Cardiac Arrest, Aiping Shi, Juan Chen, Xiaowei He, Chunyan Chen, Ming Sun, Wei Li, Wenxia Xu, Wei Yang, Xiaoqin Han Oct 2025

Characterization And Management Of Pain Across Phases Of Intraosseous Infusion In Emergency Department Patients With Non-Cardiac Arrest, Aiping Shi, Juan Chen, Xiaowei He, Chunyan Chen, Ming Sun, Wei Li, Wenxia Xu, Wei Yang, Xiaoqin Han

Saudi Medical Journal

ABSTRACT Objectives: To identify risk factors for moderate-to-severe pain during intraosseous infusion (IOI) in non-cardiac arrest patients in the emergency department (ED). Secondary aims include evaluating pain trajectory across procedural stages and assessing the efficacy of a personalized pain management strategy. Methods: This mixed-methods study analyzed 220 ED patients undergoing IOI (150 retrospective, 70 prospective). The prospective cohort was randomized to standard care (n=35) or personalized pain management (n=35). Pain was quantified using the numeric rating scale (NRS) and critical-care pain observation tool (CPOT). Results: During puncture, 35.33% (53/150) reported no/mild pain. Pain severity peaked during flushing, with 73.33% (110/150) …


Finding Aid For University Of Mississippi Small Manuscripts(Mum01771) Oct 2025

Finding Aid For University Of Mississippi Small Manuscripts(Mum01771)

Archives & Special Collections: Finding Aids (alphabetical)

The collection contains items related to the University of Mississippi. The collection is arranged by subject.


Spinal Cord Injury, Children's Mercy Kansas City Oct 2025

Spinal Cord Injury, Children's Mercy Kansas City

Clinical Pathways

No abstract provided.


Insect Pests Of Wheat In North India: A Comprehensive Review Of Their Bio-Ecology And Integrated Management Strategies, Gurveer Singh, Neelendra K. Joshi Oct 2025

Insect Pests Of Wheat In North India: A Comprehensive Review Of Their Bio-Ecology And Integrated Management Strategies, Gurveer Singh, Neelendra K. Joshi

Entomology and Plant Pathology Faculty Publications and Presentations

Wheat (Triticum aestivum L.) is a vital food crop for majority of the world's population. However, its yield potential is significantly threatened by insect pests, which adversely affect production, quality, and overall food security. The diverse array of insect pests throughout wheat's growth stages necessitates a comprehensive understanding of their interactions with wheat cultivation. This review critically assesses the diversity, biology, ecology, and management strategies of major insect pests in North India, including aphids, termites, pink stem borer, gram pod borer, armyworm, and brown wheat mite. These pests infest wheat at various growth stages, posing significant challenges to sustainable production. …


Screen Time, Physical Activity, And Vo₂Max In Indonesian Vocational School Adolescents (Aged 15–17): A Cross-Sectional Study, Cahyo Wibowo, Yahya Eko Nopiyanto, Angkit Kinasih, Asarya Reno Kombong, Dian Pujianto, Bayu Insanistyo Oct 2025

Screen Time, Physical Activity, And Vo₂Max In Indonesian Vocational School Adolescents (Aged 15–17): A Cross-Sectional Study, Cahyo Wibowo, Yahya Eko Nopiyanto, Angkit Kinasih, Asarya Reno Kombong, Dian Pujianto, Bayu Insanistyo

Indonesian Journal of Research in Physical Education, Sport, and Health

Physical activity and screen time influence many adolescent' fitness problems. This research aims to determine the relationship between screen time and physical activity on adolescent students' cardio-respiratory endurance (VO2max). This research used observational analysis with a cross-sectional study involving 70 teenage students at an Information and Network Technology Vocational School consisting of male and female teenage students. The Screen Time of Adolescents (QUEST) questionnaire was used to assess screen time, the physical activity instrument used the Global Physical Activity Questionnaire (GPAQ v2.0) to assess physical activity levels, and the VO2max instrument used the 20-meter Multistage Fitness Test (MFT). The data …


Association Between Suboptimal Health Status And Academic Performance: A Cross-Sectional Study Of 1,028 Medical Students In Punjab, Pakistan, Maleha Asim, Misbah Malik, Aneela Jamil, Raheela Yasmin, Ghazala Jawwad, Wajahat Ullah Khan Oct 2025

Association Between Suboptimal Health Status And Academic Performance: A Cross-Sectional Study Of 1,028 Medical Students In Punjab, Pakistan, Maleha Asim, Misbah Malik, Aneela Jamil, Raheela Yasmin, Ghazala Jawwad, Wajahat Ullah Khan

Indonesian Journal of Research in Physical Education, Sport, and Health

Background: Suboptimal health status (SHS) refers to the transitional period between health and illness, characterized by unexplained symptoms and premature changes in functional status without a known medical diagnosis. Objective: The aim is to examine how often SHS occurs and how lifestyle factors influence both SHS and the academic success of medical students. Methods: A Cross-sectional survey was conducted from February 2024 to September 2024 with first- to fifth-year medical students from four randomly chosen medical colleges in Punjab, Pakistan. The Suboptimal Health Measurement Scale (SHMS V1.0), Pittsburgh Sleep Quality Index (PSQI), and Health-Promoting Lifestyle Scale (HPLS) were used to …


A New Multisystem Ercc1-Hepatorenal Syndrome: Insights From A Clinical Cohort, Molecular Pathogenesis, And Management Guidelines., Susan M. White, Annelotte P. Wondergem, Isa Breet, Maren Dittmaier, Katrina Bell, Christopher M. Richmond, Winita Hardikar, Kanika Bhatia, Catherine Quinlan, David Orchard, Areetha D'Souza, Walter J. Chazin, Christopher Smith, Rebecca Sparkes, Simon Lam, Alexandra Carter, Robert J. Hopkin, Leticia Khendek, Bonnie Sullivan, Naja Becher, Anne Katrine W. Simonsen, Helene Kvistgaard, Katherine Dempsey, Alexander G. Miethke, Pernille Axél Gregersen, Eliza Phillips, Martijn S. Luijsterburg Oct 2025

A New Multisystem Ercc1-Hepatorenal Syndrome: Insights From A Clinical Cohort, Molecular Pathogenesis, And Management Guidelines., Susan M. White, Annelotte P. Wondergem, Isa Breet, Maren Dittmaier, Katrina Bell, Christopher M. Richmond, Winita Hardikar, Kanika Bhatia, Catherine Quinlan, David Orchard, Areetha D'Souza, Walter J. Chazin, Christopher Smith, Rebecca Sparkes, Simon Lam, Alexandra Carter, Robert J. Hopkin, Leticia Khendek, Bonnie Sullivan, Naja Becher, Anne Katrine W. Simonsen, Helene Kvistgaard, Katherine Dempsey, Alexander G. Miethke, Pernille Axél Gregersen, Eliza Phillips, Martijn S. Luijsterburg

Manuscripts, Articles, Book Chapters and Other Papers

DNA repair disorders are a group of conditions characterized by progressive, multisystem phenotypes. Defining new clinical presentations of these disorders is essential for optimizing patient care. ERCC1-XPF is a multifunctional endonuclease involved in nucleotide excision repair (NER) and interstrand crosslink (ICL) repair. We sought to define a novel multisystem phenotype associated with biallelic ERCC1 variants and impaired DNA repair. Through international collaboration, we identified seven individuals from five families carrying biallelic ERCC1 variants, including p.Arg156Trp and p.Ala266Pro, who exhibited a distinct clinical phenotype. All individuals presented with growth restriction, photosensitivity, and kidney and liver dysfunction. Notably, three children required liver …


Associations Among Human Milk Polyunsaturated Fatty Acids And Infant Sleep Patterns: A Cross-Sectional Study, Ana M Palacios, Dominick J Lemas, Bridget E Young, Erik Parker, Stephanie Dickinson, Nandi Marshall, Kelly L Sullivan, Haley Wilt, Michelle I Cardel, David B Allison Oct 2025

Associations Among Human Milk Polyunsaturated Fatty Acids And Infant Sleep Patterns: A Cross-Sectional Study, Ana M Palacios, Dominick J Lemas, Bridget E Young, Erik Parker, Stephanie Dickinson, Nandi Marshall, Kelly L Sullivan, Haley Wilt, Michelle I Cardel, David B Allison

Children’s Nutrition Research Center Staff Publications

Background: Infant sleep is critical for cognitive, emotional, and long-term health outcomes. Although diet-sleep relationships are established, limited research has explored how polyunsaturated fatty acids (PUFAs) in human milk (HM) relate to infant sleep.

Objectives: This study aims to examine associations between PUFAs in HM and sleep patterns in 2-mo-old infants exclusively fed with HM.

Methods: This cross-sectional secondary analysis used data from a lactation cookie trial involving 131 parents of healthy, term infants. Participants provided a fasting HM sample and completed sociodemographic and Brief Infant Sleep Questionnaire surveys. Multivariate linear models were adjusted for infant sex assigned at birth, …


All-Cause And Cause-Specific Mortality Among Patients With Narcolepsy., Chih-Wei Hsu, Yen-Shan Yang, Yang-Chieh Brian Chen, Liang-Jen Wang, Mu-Hong Chen, Yao-Hsu Yang, Chih-Sung Liang, Edward Chia-Cheng Lai Oct 2025

All-Cause And Cause-Specific Mortality Among Patients With Narcolepsy., Chih-Wei Hsu, Yen-Shan Yang, Yang-Chieh Brian Chen, Liang-Jen Wang, Mu-Hong Chen, Yao-Hsu Yang, Chih-Sung Liang, Edward Chia-Cheng Lai

Children’s Nutrition Research Center Staff Publications

Importance: Narcolepsy is a sleep disorder potentially affecting mortality, yet evidence on this association remains sparse.

Objective: To examine whether narcolepsy is associated with an increased risk of all-cause and cause-specific mortality.

Design, setting, and participants: This retrospective cohort study used data from the Taiwan National Health Insurance Research Database (NHIRD) from 2001 to 2021, with patients followed up until death or December 31, 2022. Patients were aged 6 years or older with 2 or more narcolepsy diagnoses from psychiatrists or neurologists. Controls were selected from the NHIRD as a population-based sample. Controls without narcolepsy were matched in a 1:4 …


Menopause Factors And Alterations In Gut Microbiota And Insulin Homeostasis: A Cross-Sectional Analysis Of The Microbiome And Insulin Longitudinal Evaluation Study (Miles), Vincent J Maffei, Alain G Bertoni, Alexis C Wood, Jerome I Rotter, Osa Crago, Yii-Der I Chen, Joseph F Petrosino, Kristi L Hoffman, Mark O Goodarzi, Elizabeth T Jensen Oct 2025

Menopause Factors And Alterations In Gut Microbiota And Insulin Homeostasis: A Cross-Sectional Analysis Of The Microbiome And Insulin Longitudinal Evaluation Study (Miles), Vincent J Maffei, Alain G Bertoni, Alexis C Wood, Jerome I Rotter, Osa Crago, Yii-Der I Chen, Joseph F Petrosino, Kristi L Hoffman, Mark O Goodarzi, Elizabeth T Jensen

Children’s Nutrition Research Center Staff Publications

Aim: To assess the risk for impaired insulin homeostasis as a function of menopause-related factors and gut microbiota dysbiosis in non-diabetic, post-menopausal women.

Materials and methods: Baseline data (n = 175 women) from the Microbiome and Insulin Longitudinal Evaluation Study (MILES) were used, including insulin and dysglycaemia indices calculated from a 2-h oral glucose tolerance test, untargeted peripheral metabolomics, targeted peripheral short chain fatty-acid levels and faecal bacterial microbiota surveyed by whole-metagenomic sequencing.

Results: After adjustment for covariates, menopause age < 50 years and use of hormone replacement therapy (HRT) were associated with lower Matsuda et al. insulin sensitivity index levels (β = -0.232, confidence interval (CI) = [-0.450, -0.014] and β = -0.275, CI = [-0.444, -0.107], respectively) but not pre-menopausal gynaecologic surgery. Pre-menopausal gynaecologic surgery was significantly associated with faecal microbiota beta diversity driven by a relative increase in diabetogenic Ruminococcus gnavus and Clostridium species and a decrease in protective Alistipes species and Akkermansia muciniphila relative abundances. A reduction in two glycerophospholipids in the plasmalogen class significantly statistically mediated an inverse association between gynaecologic surgery before menopause and insulin sensitivity.

Conclusions: Menopause age and history of HRT are more strongly associated with insulin resistance than gynaecologic surgery before menopause. However, …


From Holistic To Localized: Local Enhanced Adapters For Efficient Visual Instruction Fine-Tuning, Pengkun Jiao, Bin Zhu, Jingjing Chen, Chong-Wah Ngo, Yugang Jiang Oct 2025

From Holistic To Localized: Local Enhanced Adapters For Efficient Visual Instruction Fine-Tuning, Pengkun Jiao, Bin Zhu, Jingjing Chen, Chong-Wah Ngo, Yugang Jiang

Research Collection School Of Computing and Information Systems

Efficient Visual Instruction Fine-Tuning (EVIT) seeks to adapt Multimodal Large Language Models (MLLMs) to downstream tasks with minimal computational overhead. However, as task diversity and complexity increase, EVIT faces significant challenges in resolving data conflicts. To address this limitation, we propose the Dual Low-Rank Adaptation (Dual-LoRA), a holistic-to-local framework that enhances the adapter’s capacity to address data conflict through dual structural optimization. Specifically, we utilize two subspaces: a skill space for stable, holistic knowledge retention, and a rank-rectified task space that locally activates the holistic knowledge. Additionally, we introduce Visual Cue Enhancement (VCE), a multi-level local feature aggregation module designed …


Exploring Object Status Recognition For Recipe Progress Tracking In Non-Visual Cooking, Franklin Mingzhe Li, Kaitlyn Ng, Bin Zhu, Patrick Carrington Oct 2025

Exploring Object Status Recognition For Recipe Progress Tracking In Non-Visual Cooking, Franklin Mingzhe Li, Kaitlyn Ng, Bin Zhu, Patrick Carrington

Research Collection School Of Computing and Information Systems

Cooking plays a vital role in everyday independence and well-being, yet remains challenging for people with vision impairments due to limited support for tracking progress and receiving contextual feedback. Object status — the condition or transformation of ingredients and tools — offers a promising but underexplored foundation for context-aware cooking support. In this paper, we present OSCAR (Object Status Context Awareness for Recipes), a technical pipeline that explores the use of object status recognition to enable recipe progress tracking in non-visual cooking. OSCAR integrates recipe parsing, object status extraction, visual alignment with cooking steps, and time-causal modeling to support real-time …


Advancing University Student Health And Wellbeing Through Peer-Led Health Promotion: A Quality Improvement Project​ ​, Rojeda Merani, Elizabeth Page, Elizabeth Roth Oct 2025

Advancing University Student Health And Wellbeing Through Peer-Led Health Promotion: A Quality Improvement Project​ ​, Rojeda Merani, Elizabeth Page, Elizabeth Roth

DNP Projects

Background: Peer-led health promotion is widely recognized as an effective strategy for increasing engagement, trust, and health literacy among university students. However, few frameworks guide development and implementation of these programs.

Objective: To evaluate the feasibility, implementation process, and perceived effectiveness of a peer-led health promotion model supported by Doctor of Nursing Practice (DNP) mentorship at a mid-sized private university.

Participants: Thirteen undergraduate students from a diverse set of academic programs were recruited as Peer Health Ambassadors (PHAs) and paired with DNP student mentors.

Methods: Guided by the Implementation Research Logic Model, the project used a four-phase QI process: targeted …


¡Charlemos De Comida Y Cultura En España!, Lucia Osa-Melero Oct 2025

¡Charlemos De Comida Y Cultura En España!, Lucia Osa-Melero

Open Education Materials

¡Charlemos de comida y cultura en España! is a culturally immersive Spanish language textbook designed for intermediate- high level learners who wish to explore the rich and diverse culinary traditions of Spain while enhancing their linguistic skills. Organized thematically by culinary concepts, this text blends language instruction with cultural insights to provide a meaningful and engaging learning experience while developing communicative skills and intercultural learning. Each chapter introduces students to regional specialties, food-related vocabulary, idiomatic expressions, and authentic readings and videos that reflect the traditions, values, and social common practices surrounding food in Spain.


Myplate For Healthy Diet And Physical Activity: A Pilot Project, Christin Sullivan Oct 2025

Myplate For Healthy Diet And Physical Activity: A Pilot Project, Christin Sullivan

Doctor of Nursing Practice

Background: Over 100 million American adults are obese. This has increased from 38.5% in 2013-2016 to 41.8% in 2017-2020 and is predicted to keep rising. Significant health risks are linked to obesity, prompting weight loss movements at the local, national and global level. Recently, Semaglutide has been favored in weight loss programs but must be augmented by education on healthy diet and physical activity for weight reduction and maintenance.

Purpose: The purpose of this scholarly project was to pilot the MyPlate method on healthy diet and physical activity and determine its effects on patient knowledge of healthy diet and physical …


In Support Of Free Speech On Food Production, Nicole Ligon Oct 2025

In Support Of Free Speech On Food Production, Nicole Ligon

Penn State Law Review (2003 - Present)

No abstract provided.


The Anchor: October 2025, Hope College Oct 2025

The Anchor: October 2025, Hope College

The Anchor: 2025

The Anchor began in 1887 and was first issued weekly in 1914. Covering national and campus news alike, Hope College’s student-run newspaper has grown over the years to encompass over two-dozen editors, reporters, and staff. For much of The Anchor's history, the latest issue was distributed across campus each Wednesday throughout the academic school year (with few exceptions). In recent years The Anchor moved to monthly print issues and a more frequently updated website. The Anchor is now published in print twice per academic semester. Occasionally, the volume and/or issue numbering is irregular.


The Bulletin: Sidney Kimmel Medical College At Thomas Jefferson University, Volume 103, Issue 2, Fall 2025 Oct 2025

The Bulletin: Sidney Kimmel Medical College At Thomas Jefferson University, Volume 103, Issue 2, Fall 2025

The Bulletin (formerly the Jefferson Medical College Alumni Bulletin)

This issue includes:

  • 5 - Dean’s Column
  • 6 - Time Machine
  • 12 - ICYMI (In Case You Missed It)
  • 18 - Medicine Rooted in Connection by Scott Orlov, SKMC Class of 2026
  • 20 - All in the Family by Takami Sato, MD, PhD, and Rino Seedor, MD ’15
  • 24 - When Jefferson and Medicine Struck Gold by Geno J. Merli, MD ’75, RES ’78 and ’80
  • 28 - Alumni Weekend Recap
  • 32 - Born a Jeffersonian by William Valentine Harrer, MD ’62
  • 35 - Class Ambassadors
  • 36 - A Message From the SKMC Alumni Board President
  • 38 - Class Notes …


Investigating Machine Learning Algorithms To Classify Label-Free Images Of Pancreatic Neuroendocrine Neoplasms, Noelle Daigle, Shuyuan Guan, Suzann Duan, Thomas G Knapp, Eung-Joo Lee, Ali Azhdarinia, Sukhen C Ghosh, Solmaz Aghaamiri, Servando Hernandez Vargas, Naruhiko Ikoma, Jeannelyn Estrella, Martin J Schnermann, Tobias Else, Michelle Kang Kim, Juanita L Merchant, Travis W Sawyer Oct 2025

Investigating Machine Learning Algorithms To Classify Label-Free Images Of Pancreatic Neuroendocrine Neoplasms, Noelle Daigle, Shuyuan Guan, Suzann Duan, Thomas G Knapp, Eung-Joo Lee, Ali Azhdarinia, Sukhen C Ghosh, Solmaz Aghaamiri, Servando Hernandez Vargas, Naruhiko Ikoma, Jeannelyn Estrella, Martin J Schnermann, Tobias Else, Michelle Kang Kim, Juanita L Merchant, Travis W Sawyer

The Brown Foundation: Institute of Molecular Medicine

Significance: Pancreatic neuroendocrine neoplasms (PNENs) are an uncommon cancer whose incidence rate has increased dramatically in recent years. Surgery is the only potentially curative treatment, which relies on both preoperative tumor localization and postoperative margin definition using histopathological examination for decision making. If pathology could be automated, valuable time and resources could be saved.

Aim: In this study, we investigate the ability of machine learning (ML) with handcrafted features, as well as deep learning, to classify label-free microscopy images of PNENs as a first step toward automated pathology of such tumors.

Approach: Patient samples of two different preparation types were …


Chemistry And Biochemistry Affiliated Publications: Snapshot Of The Research Publications 2019-2024., Jeremy J. Smith, Lutishoor Salisbury Oct 2025

Chemistry And Biochemistry Affiliated Publications: Snapshot Of The Research Publications 2019-2024., Jeremy J. Smith, Lutishoor Salisbury

University Libraries Faculty Publications and Presentations

This report highlights the chemistry and biochemistry faculty publications for the period 2019-2024. It includes tables identifying the types of publications, the characteristics of the authors, inter-departmental and external cooperation, summary of the citations of the publications, and the JCR ranking of the journals in which they published.


Mechanisms For The Age-Related Increase In Fatigability Of The Elbow Flexor Muscles In Healthy Adults, Blaine E. Arney, Andrew Kuplic, Mitchell D. Adam, Christopher W. Sundberg, Sandra Hunter Oct 2025

Mechanisms For The Age-Related Increase In Fatigability Of The Elbow Flexor Muscles In Healthy Adults, Blaine E. Arney, Andrew Kuplic, Mitchell D. Adam, Christopher W. Sundberg, Sandra Hunter

Exercise Science Faculty Research and Publications

The mechanisms for the age-related increase in fatigability of the elbow flexor muscles during dynamic contractions are unknown. The purpose of this study was to determine the contribution of supraspinal and contractile mechanisms for the age-related increase in fatigability of the elbow flexor muscles. Twenty-eight young (23.2 ± 2.6 years; 14 females) and 32 older adults (72.6 ± 5.6 years; 15 females) performed 80 maximal velocity contractions at 20% of maximal isometric strength. Voluntary activation and muscle contractile properties were assessed before and immediately following the fatiguing exercise using transcranial magnetic stimulation (TMS) and electrical stimulation. Fatigability (% reduction in …


Endoscopic Submucosal Dissection For Previously Attempted Colorectal Lesions: An International Multicenter Experience., Suchapa Arayakarnkul, Hiroyuki Aihara, Alessandro Repici, Roberta Maselli, Antonio Capogreco, Leonardo Da Rio, Fabio Shiguehissa Kawaguti, Fauze Maluf-Filho, Makoto Nishimura, Sera Satoi, Sayaka Nagao, Shai Friedland, Robert Bechara, Norio Fukami, Sonmoon Mohapatra, Amit Bhatt, Abel Joseph, Alex Schlachterman, Anand Kumar, Andrew Y Wang, Ross C D Buerlein, Louis M Wong Kee Song, Fnu Deepali, Dennis Yang, Muhammad K Hasan, Nikhil A Kumta, David L Diehl, Edward J Despott, Alberto Murino, Alessandro Rimondi, Laura Lucaciu, Neil R Sharma, Christina Zelt, Ashley Rumple Rn, Bsn, David Leslie Carr-Locke, Reem Z Sharaiha, Srihari Mahadev, Kamal M Hassan, Mohamad-Noor Abu-Hammour, Carlos Robles-Medranda, Martha Arevalo-Mora, Juan Alcivar-Vasquez, Vivek Kumbhari, Jongkyu Park, Salmaan Jawaid, Mai A Khalaf, Kasenee Tiankanon, Sarah S Al Ghamdi, Mohamed O Othman, Saowanee Ngamruengphong Oct 2025

Endoscopic Submucosal Dissection For Previously Attempted Colorectal Lesions: An International Multicenter Experience., Suchapa Arayakarnkul, Hiroyuki Aihara, Alessandro Repici, Roberta Maselli, Antonio Capogreco, Leonardo Da Rio, Fabio Shiguehissa Kawaguti, Fauze Maluf-Filho, Makoto Nishimura, Sera Satoi, Sayaka Nagao, Shai Friedland, Robert Bechara, Norio Fukami, Sonmoon Mohapatra, Amit Bhatt, Abel Joseph, Alex Schlachterman, Anand Kumar, Andrew Y Wang, Ross C D Buerlein, Louis M Wong Kee Song, Fnu Deepali, Dennis Yang, Muhammad K Hasan, Nikhil A Kumta, David L Diehl, Edward J Despott, Alberto Murino, Alessandro Rimondi, Laura Lucaciu, Neil R Sharma, Christina Zelt, Ashley Rumple Rn, Bsn, David Leslie Carr-Locke, Reem Z Sharaiha, Srihari Mahadev, Kamal M Hassan, Mohamad-Noor Abu-Hammour, Carlos Robles-Medranda, Martha Arevalo-Mora, Juan Alcivar-Vasquez, Vivek Kumbhari, Jongkyu Park, Salmaan Jawaid, Mai A Khalaf, Kasenee Tiankanon, Sarah S Al Ghamdi, Mohamed O Othman, Saowanee Ngamruengphong

PCI Publications and Projects

BACKGROUND & AIMS: Salvage endoscopic submucosal dissection (ESD) has been proposed for previously attempted colorectal lesions (PACLs), yet the extensive submucosal fibrosis impacts procedural difficulty and resection outcomes. The aim of this study was to evaluate the efficacy and safety of salvage ESD for the treatment of PACLs.

METHODS: This international, multicenter study enrolled consecutive patients who underwent ESD to manage PACLs. Rates of en bloc, R0 resection, and local recurrence were assessed for efficacy. Safety was assessed by adverse events (AEs), procedure-related mortality, and the need for surgical management.

RESULTS: Of 415 lesions, en bloc rate was 83.4%, the …


Harnessing Rice Glutelin And Chickpea Proteins Interactions To Enhance Functional And Nutritional Qualities Of Plant-Based Cheese, Nikitha Modupalli, Md Mahfuzur Rahman Oct 2025

Harnessing Rice Glutelin And Chickpea Proteins Interactions To Enhance Functional And Nutritional Qualities Of Plant-Based Cheese, Nikitha Modupalli, Md Mahfuzur Rahman

Food Science Faculty Publications and Presentations

The recent demand for plant-based dairy alternatives has increased the focus on improving the organoleptic, and nutritional attributes of plant cheeses to match their dairy counterparts. This study aimed to develop a functional cheese using the synergistic interactions of rice glutelin and chickpea proteins to enhance both nutritional and textural properties. Functional characterization revealed that rice glutelin exhibited a higher water-holding capacity of 340 % and elevated solubility, while chickpea protein showed a superior oil-holding capacity of 550 % and higher surface hydrophobicity. Cheeses were prepared using a 40:60 blend of rice glutelin to chickpea protein, which yielded 21.3 % …


Refugee Health And Nutrition, Miriam Mutambudzi, Naomi Shanguhyia Oct 2025

Refugee Health And Nutrition, Miriam Mutambudzi, Naomi Shanguhyia

The Lender Center for Social Justice

Refugees resettled in Syracuse, New York, face persistent challenges to maintaining healthy, culturally appropriate diets, barriers that extend far beyond food availability. This policy brief explores the complex intersection of nutrition, culture, and health equity among refugee families. Through community-engaged research with sub-Saharan African refugee households, findings reveal that food insecurity remains widespread, with families struggling to access familiar ingredients and affordable, nutritious options. Despite these constraints, refugee families demonstrate remarkable resilience and commitment to preserving traditional diets and promoting health within their households. However, limited cultural competence in food assistance programs and exposure of youth to unhealthy dietary norms …