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2025

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Commonwealth Times 2025-11-05 Nov 2025

Commonwealth Times 2025-11-05

Commonwealth Times, 1969-

No abstract provided.


Strengthening The Utah Diabetes Cook Along Program For Statewide Extension Delivery: Curriculum Refinement And Randomized Controlled Trial, Carrie Durward Nov 2025

Strengthening The Utah Diabetes Cook Along Program For Statewide Extension Delivery: Curriculum Refinement And Randomized Controlled Trial, Carrie Durward

Funded Research Records

No abstract provided.


Circulating Levels Of Insulin-Like Growth Factor I (Igf-I) And Risk Ofmultiple Myeloma: An Observational And Mendelian Randomisation Study, Yolanda Benavente, Sara Hermosa, Nikos Papadimitriou, Alyssa I. Clay-Gilmour Ph.D., Elizabeth E. Brown, Jonathan N. Hofmann, Nathaniel Rothman, Qing Lan, Sonja I. Berndt, Demetrius Albanes, Mark Purdue, Mitchell J. Machiela, Stephen J. Chanock, Parveen Bhatti, Wendy Cozen, Aaron Norman, Susan L. Slager, James R. Cerhan, Vincent Rajkumar, Shaji J. Kumar, Et. Al. Nov 2025

Circulating Levels Of Insulin-Like Growth Factor I (Igf-I) And Risk Ofmultiple Myeloma: An Observational And Mendelian Randomisation Study, Yolanda Benavente, Sara Hermosa, Nikos Papadimitriou, Alyssa I. Clay-Gilmour Ph.D., Elizabeth E. Brown, Jonathan N. Hofmann, Nathaniel Rothman, Qing Lan, Sonja I. Berndt, Demetrius Albanes, Mark Purdue, Mitchell J. Machiela, Stephen J. Chanock, Parveen Bhatti, Wendy Cozen, Aaron Norman, Susan L. Slager, James R. Cerhan, Vincent Rajkumar, Shaji J. Kumar, Et. Al.

Faculty Publications

Evidence for an association between insulin-like growth factors (IGF) and multiple myeloma (MM) is inconsistent. We examined total IGF-I concentrations and risk of MM by combining baseline serological data among UK Biobank participants (n = 444 187; 732 incident MM) with a two-sample Mendelian randomisation (MR) analysis using identified genetic variants associated with circulating total IGF-I and IGF-binding protein 3 (IGFBP-3) in the InterLymph consortium (2434 MM and their 2567 controls). Finally, additional lymphoid neoplasm (LN) subtypes were included for comparison with the main hypothesis. Circulating IGF-I level was positively associated with MM risk Hazard ratio-HR-per one standard deviation-SD-increase …


The Bg News November 5, 2025, Bowling Green State University Nov 2025

The Bg News November 5, 2025, Bowling Green State University

BG News (Student Newspaper)

The BGSU campus student newspaper. November 05, 2025. Volume 105-Issue 10.


2025-11-05 November Snap Benefits, While Reduced, Survive Cancellation From Shutdown, Kean Mathis Nov 2025

2025-11-05 November Snap Benefits, While Reduced, Survive Cancellation From Shutdown, Kean Mathis

The Spectator Online

No abstract provided.


Spectrum, Volume 55, Issue 8, Sacred Heart University Nov 2025

Spectrum, Volume 55, Issue 8, Sacred Heart University

Newspapers (Obelisk & Spectrum)

Highlights include: Dr. Petillo’s Continued Presidency -- Too Many Swipes, Not Enough Dollars? -- The “Heart” of HeartLines Magazine -- Sprinting into Community --Finding Food Balance on a Budget -- Women’s Rugby Landslide Season Finisher


Impact Of Crop Rotation And Species Variation On Soil Quality Indicators, Somasekhar Auduti, Uday Kiran Pittala, Pratibha Adhikari Nov 2025

Impact Of Crop Rotation And Species Variation On Soil Quality Indicators, Somasekhar Auduti, Uday Kiran Pittala, Pratibha Adhikari

Scholars Week

Impact of Crop Rotation and Species Variation on Soil Quality Indicators

Pratibha Adhikari, Somasekhar Auduti, Uday Kiran Pittala

Mentor: Dr. Iin P. Handayani, Ph.D.

Hutson School of Agriculture, Murray State University, Murray, KY, USA

Designing crop rotations that counter the negative effects of monocropping requires crop choices that build carbon and create stable pore structure. The objective of this research was to evaluate the effects of crop rotation on selected soil health indicators and to interpret soil health conditions across agricultural fields. Soil samples were collected from West Farm, Murray, KY, from six crop fields—corn, soybean, tobacco, millet, cotton, and …


Assessing Soil Quality Indicators In Leguminous And Non-Leguminous Cropping Systems, Kabita Budthapa, Kranthi Vinukonda, Ramya Sree Teeguri Nov 2025

Assessing Soil Quality Indicators In Leguminous And Non-Leguminous Cropping Systems, Kabita Budthapa, Kranthi Vinukonda, Ramya Sree Teeguri

Scholars Week

It is crucial to understand how different cropping systems influence soil health to boost the efficiency of resources and sustainable agricultural outputs. This study examined the effects of leguminous (soybean and pea) and non-leguminous (sunflower and maize) cropping systems on selected soil characteristics. On September 16th, 2025, soil samples (24 disturbed and 24 undisturbed) were collected from the 0-7.5 cm depth of West Farm, Murray, Kentucky. Disturbed samples were analyzed for pH, soil organic matter (SOM), and soil organic carbon (SOC), while undisturbed samples were used to determine bulk density, porosity, soil water holding capacity (SWHC), and soil water field …


Planning For Prevention: Implementing Pressure Injury Bundles In Hospice Settings, Ellie M. Martin, Mckenzie Pool Nov 2025

Planning For Prevention: Implementing Pressure Injury Bundles In Hospice Settings, Ellie M. Martin, Mckenzie Pool

Scholars Week

There is an increased prevalence of pressure-related injuries in the hospice setting. This can be due to age, diagnosis, comorbidities, inadequate nutrition or hydration, lack of mobility, or inadequate care due to lack of education. Prevention bundles and policies are at every facility, but are not as effective as needed. This looks at the theoretical framework and ways to prevent pressure injuries as effectively as possible. Pulling information from multiple other research studies to put the best care bundle together to decrease the amount of pressure injuries.


(((Qpie))) A Unified Field Of Meaning, Measurement, And Human Potential, Teddy Burroughs Nov 2025

(((Qpie))) A Unified Field Of Meaning, Measurement, And Human Potential, Teddy Burroughs

Defensive Publications Series

A Unified Field of Meaning, Measurement, and Human Potential

QPIE: The Quantum Perspective Is Everything

A Unified Field of Meaning, Measurement, and Human Potential

Date: November 4 2025 Author: Teddy Burroughs (#TedFunding) (Inspired by Aleah Burroughs, Kaiya Burroughs, Briana Burroughs, Reya Burroughs, Teddy Burroughs Jr, Arylise Burroughs) Affiliations: Avision4Change | Vision2Funding | Voyager | Aetheris — under the QPIE OS Banner

I. The Birth of QPIE — From Observation to Participation

Every scientific revolution begins when an old boundary dissolves. Newton separated matter from mind; Einstein fused space and time; quantum theory, in its most unsettling twist, revealed that the …


Public Housing Professionals Perspectives On Mobile Food Unit Location And Accessibility For Children, Antoinette Lashurn Simpson Nov 2025

Public Housing Professionals Perspectives On Mobile Food Unit Location And Accessibility For Children, Antoinette Lashurn Simpson

Walden Dissertations and Doctoral Studies

Poor nutrition is a major contributor to death in the United States, and residents of public housing face disproportionate challenges in maintaining adequate nutrition. Public housing is the nation’s oldest housing subsidy program, providing more than one million units for millions of residents, many of whom are women, minorities, and unmarried individuals with incomes below the poverty line. The purpose of this generic qualitative study was to explore public housing professionals’ perspectives on using a mobile food unit located within housing communities to help reduce food insecurity. Feminist intersectionality theory provided the framework for this study, emphasizing how overlapping systems …


Enhancing Diabetes Self-Management Education And Support Knowledge And Awareness Among Nurses, Tamba Sam-Manimoi Nov 2025

Enhancing Diabetes Self-Management Education And Support Knowledge And Awareness Among Nurses, Tamba Sam-Manimoi

Walden Dissertations and Doctoral Studies

Diabetes mellitus (DM) affects 12% of the United States population at an annual cost of $412.9 billion. In the local clinic, 20% of the patient population has a diagnosis of DM. Despite the importance of diabetes self-management education and support (DSMES) in managing DM, patients are often not educated on this important strategy. Leadership identified that patients were reporting a lack of knowledge regarding DSMES practices and that the nurses lacked the necessary knowledge and awareness to educate patients in DSMES. Thus, the purpose of this DNP project was to determine if an educational intervention focused on DM and DSMES …


Dialysis Social Workers' Perceptions Of Strategies To Address Biopsychosocial-Spiritual Barriers To End-Of-Life Planning With Black Dialysis Patients, Annette Carol Kestner Nov 2025

Dialysis Social Workers' Perceptions Of Strategies To Address Biopsychosocial-Spiritual Barriers To End-Of-Life Planning With Black Dialysis Patients, Annette Carol Kestner

Walden Dissertations and Doctoral Studies

Black individuals with end-stage renal disease (ESRD) have an excessive risk of mortality and experience ongoing inequities in end-of-life (EOL) planning. This basic qualitative study, informed by Sulmasy's biopsychosocial-spiritual model, explored social workers' perspectives about approaches that consider the interplay of physical, psychological, social, and spiritual aspects for mitigating barriers to EOL planning among Black dialysis patients. Data were obtained from semi structured interviews with 10 licensed dialysis social workers in Virginia and Maryland. Thematic analysis with descriptive coding, reflexive journaling, and peer debriefing was employed to analyze qualitative data to ensure trustworthiness. Six themes were identified: (a) building trust …


Spartan Daily, November 4, 2025, San Jose State University, School Of Journalism And Mass Communications Nov 2025

Spartan Daily, November 4, 2025, San Jose State University, School Of Journalism And Mass Communications

Spartan Daily, 2025

Volume 165, Issue 31


Improving Coral Restoration Outcomes Through Novel Molecular Applications, Matthew H. Gamache Nov 2025

Improving Coral Restoration Outcomes Through Novel Molecular Applications, Matthew H. Gamache

USF Tampa Graduate Theses and Dissertations

Coral reef ecosystems are declining globally from numerous stressors, including localized pollution, disease, and marine heatwaves induced by climate change. To preserve these ecosystems, it is critical to identify corals that can withstand stressors—primarily future marine heatwaves—and prioritize them for coral restoration efforts until these stressors are mitigated. Coral responses to thermal stress can be influenced by several partners, including mutualistic microalgae and a vast prokaryotic community. Here, I use advanced molecular techniques to examine which partners (coral host, algal symbiont, and microbial communities) are associated with coral health, how they contribute to holobiont physiology, and their potential to increase …


Global Trends And Forecast Of Cardiovascular Diseases, Cancer, And Shared Risk Factors: Insights From The Gbd 2021, Chieh Y Koo, Bryan Chong, Jayanth Jayabaskaran, Srinithy Nagarajan, Silingga M Jauhari, Yiming Chen, Li L Tan, Anurag Mehta, Muhammad S Khan, Mark Muthiah, Derek Hausenloy, A M Richards, Dennis T Ko, Christian D Mallen, Eric A Secemsky, Mark Y Chan, Paaladinesh Thavendiranathan, Nicholas W S Chew, Mamas A Mamas Nov 2025

Global Trends And Forecast Of Cardiovascular Diseases, Cancer, And Shared Risk Factors: Insights From The Gbd 2021, Chieh Y Koo, Bryan Chong, Jayanth Jayabaskaran, Srinithy Nagarajan, Silingga M Jauhari, Yiming Chen, Li L Tan, Anurag Mehta, Muhammad S Khan, Mark Muthiah, Derek Hausenloy, A M Richards, Dennis T Ko, Christian D Mallen, Eric A Secemsky, Mark Y Chan, Paaladinesh Thavendiranathan, Nicholas W S Chew, Mamas A Mamas

Faculty, Staff and Students Publications

Background: Cardiovascular disease (CVD) and cancer share multiple risk factors and are the leading causes of morbidity and death worldwide. This study aims to examine historical and projected trends of the combined CVD-cancer global estimates and their shared risk factors.

Methods: Death and disability-adjusted life years (DALYs) associated with CVDs, cancers, and their risk factors were obtained from the GBD (Global Burden of Disease) 2021 study. Historical estimates from 1990 to 2021 and forecast data from 2025 to 2050 were examined across age groups, regions, sociodemographic index, and sex.

Results: In 2021, CVD-cancer resulted in age-standardized DALY rates of 8009 …


Two-Year Skeletal Adaptations In Development And National Level Female Figure Skaters, Chelsea Wong, Leigh Gabel, Erik Groves, Kelly Quipp, Steven Boyd, Lauren Burt Nov 2025

Two-Year Skeletal Adaptations In Development And National Level Female Figure Skaters, Chelsea Wong, Leigh Gabel, Erik Groves, Kelly Quipp, Steven Boyd, Lauren Burt

International Journal of Exercise Science

International Journal of Exercise Science 18(3): 1297-1309, 2025. https://doi.org/10.70252/ZSKN7069 Figure skaters typically have higher bone mineral density (BMD) than the general population. However, the current literature is limited to cross-sectional studies. The objective of this study was to determine two-year changes in volumetric BMD, bone microarchitecture, and estimated bone strength in elite national and development level Canadian figure skaters. Eleven female figure skaters aged 14+ years were recruited for this longitudinal study. Measurements occurred annually. High-resolution peripheral quantitative computed tomography (HR-pQCT) scans of the radius and tibia underwent three-dimensional image registration. Total (Tt), cortical (Ct) and trabecular (Tb) volumetric BMD …


Accidental Daily Dosing: Severe Methotrexate Toxicity In A Patient With Rheumatoid Arthritis, Sidra Memon, Kavitha Vemuri, Syed Uzair Mahmood, Darshit Patel Nov 2025

Accidental Daily Dosing: Severe Methotrexate Toxicity In A Patient With Rheumatoid Arthritis, Sidra Memon, Kavitha Vemuri, Syed Uzair Mahmood, Darshit Patel

Advances in Clinical Medical Research and Healthcare Delivery

This case highlights a crucial complication of oral methotrexate therapy: toxicity due to dosing errors. A patient’s daily dosing regimen, instead of the intended weekly schedule, led to a significantly excessive cumulative dose of methotrexate over a short period, resulting in severe hematologic and mucosal toxicity. This underscores the importance of clear patient education and vigilant prescription practices to prevent such errors.


Ada News - 11/3/2025, American Dental Association, Publishing Division Nov 2025

Ada News - 11/3/2025, American Dental Association, Publishing Division

ADA News

Established in 1970 as the official newspaper of the American Dental Association, the ADA News serves practicing dentists and others allied to the dental profession in the U.S. and internationally. It is the No. 1 source of news and information about the many benefits and services the ADA delivers to members daily as well as timely information on scientific, social, political and economic developments affecting dentistry and health care.


The Experience Of Administrative Burdens In Snap And Medicaid: New Evidence From A Nationally Representative Survey Of Low-Wage Workers, Stephen Roll, Mathieu Despard, Yung Chun Nov 2025

The Experience Of Administrative Burdens In Snap And Medicaid: New Evidence From A Nationally Representative Survey Of Low-Wage Workers, Stephen Roll, Mathieu Despard, Yung Chun

Center for Social Development Research

When functioning correctly, the U.S. social safety net ensures that everyone can reach a basic standard of living, regardless of economic circumstances, and provides financial support to help families who have fallen on hard times due to job losses or other adverse life events. However, the programs often have complex rules around eligibility, documentation requirements, and compliance. Those features and negative experiences with program staff impose psychological costs—collectively referred to as administrative burdens—that can make enrolling and staying in the programs difficult for many families. Drawing upon data from the Workforce Economic Inclusion and Mobility Survey of a nationally …


Exploring Perceived Parental Vulnerability In Pediatric Cancer Survivors: A Comparative Thematic Analysis Of English And Spanish-Speaking Families., Yusnavi Martinez Pineiro Nov 2025

Exploring Perceived Parental Vulnerability In Pediatric Cancer Survivors: A Comparative Thematic Analysis Of English And Spanish-Speaking Families., Yusnavi Martinez Pineiro

USF Tampa Graduate Theses and Dissertations

This study examined how perceived parental vulnerability is expressed among parents of pediatric cancer survivors and explored potential differences between Spanish-speaking and English-speaking families. Data were drawn from an existing ongoing clinical trial in the IHOPE lab of the University of South Florida, who collaborates with over 10 pediatric cancer survivorship clinics across the country. The study used a total of 26 (13 Spanish-speaking and 13 English-speaking) structured interview transcripts from parent participants. The transcripts were the first session with the parent participant, the interventionist spoke the parent’s preferred language (English or Spanish), perceived parental vulnerability was one of six …


Uav Remote Sensing For Assessment Of Conservative Management Practices In Maize-Soybean Cropping System, Aakriti Poudel Nov 2025

Uav Remote Sensing For Assessment Of Conservative Management Practices In Maize-Soybean Cropping System, Aakriti Poudel

LSU Master's Theses

Sustainable agriculture practices promote cover cropping, which enhances nutrient management and impacts subsequent crop productivity in field crop rotations. Precision agriculture technology, particularly Unmanned Aerial Vehicle (UAV) remote sensing, enables a detailed evaluation of crop management. The studies were conducted in a maize-soybean rotation system with winter cover cropping and fallow management. The maize experiment investigated the effect of nitrogen application rates and cover cropping, using UAV-derived Normalized Difference Red-Edge (NDRE) to monitor crop performance. NDRE effectively captured the N response and the effect of cover cropping across growth stages, particularly during mid-season (55-81 DAP), where it showed a strong …


Alcohol And Metabolic Stress Synergize To Dysregulate Mitochondrial Health And Lipid Metabolism; Evidence From A Hepatocyte Spheroid Model, Eden M. Gallegos, Kaitlin Couvillion, Drake Darden, Keishla Rodriguez-Graciani, Patricia E. Molina, Liz Simon Nov 2025

Alcohol And Metabolic Stress Synergize To Dysregulate Mitochondrial Health And Lipid Metabolism; Evidence From A Hepatocyte Spheroid Model, Eden M. Gallegos, Kaitlin Couvillion, Drake Darden, Keishla Rodriguez-Graciani, Patricia E. Molina, Liz Simon

School of Graduate Studies Faculty Publications

Metabolic dysfunction-associated steatotic liver disease and alcohol-associated liver disease frequently co-occur, manifesting as MetALD. Understanding the hepatocyte-specific effects of alcohol and metabolic stressors is critical to uncovering mechanisms of synergistic injury. This study evaluated the individual and combined effects of ethanol, sugars, and saturated/monounsaturated fats on hepatocyte lipid metabolism, oxidative stress, and mitochondrial function using a 3D human HepaRG spheroid model. HepaRG spheroids were treated with ethanol (50 mm), sugar (glucose and fructose), and fatty acids alone or in combination for 10 d. The combination of ethanol (E) and metabolic (sugar and fat, SF) stressors (ESF) synergistically increased triglyceride content …


Evaluation Of Integrative Oncology Modalities For Symptom Management: A Mascc/Sio Global Survey, Alexandre Chan, Reem Nasr, Daniela Arcos, Dalia Kagramanov, Chioma Asuzu, Ting Bao, Yin Ting Cheung, Jung Hye Kwon, Judith Lacey, Richard T. Lee, Maryam Lustberg, Beatrice M. Ohaeri, Santosh Rao, Enrique Soto-Perez-De-Celis, Claudia M. Witt, Ana M. Lopez Nov 2025

Evaluation Of Integrative Oncology Modalities For Symptom Management: A Mascc/Sio Global Survey, Alexandre Chan, Reem Nasr, Daniela Arcos, Dalia Kagramanov, Chioma Asuzu, Ting Bao, Yin Ting Cheung, Jung Hye Kwon, Judith Lacey, Richard T. Lee, Maryam Lustberg, Beatrice M. Ohaeri, Santosh Rao, Enrique Soto-Perez-De-Celis, Claudia M. Witt, Ana M. Lopez

Kimmel Cancer Center Faculty Papers

BACKGROUND: With growing evidence pointing towards the potential of integrative oncology modalities (IOM) in addressing cancer and cancer-treatment related symptoms, research on IOM utilization and implementation is warranted. This study examines global stakeholder perspectives on integrative oncology (IO) utilization for supportive cancer care.

METHODS: Members of the Multinational Association of Supportive Care in Cancer (MASCC) and the Society for Integrative Oncology (SIO) completed a survey on the utilization of IOM for supportive cancer care. Descriptive statistics were used to assess demographic data, IOM usage patterns, IOM education, and financial considerations for utilizing IOM.

RESULTS: Among 344 participants representing eight geographical …


National Alliance Of Sickle Cell Centers Consensus Recommendations On Sickle Cell Disease Health Maintenance: A Consensus Statement, Seethal A. Jacob, Melissa Frei-Jones, Sana Saif-Ur-Rehman, Monica L. Hulbert, Andrew R. W. O'Brien, Crawford Strunk, Anthony Villella, Ravi Talati, Amma Owusu-Ansah, Francis Coyne, Patrick T. Mcgann, Parul Rai, Robin Miller, Angeli Rampersad, Vishwas Sakhalkar, Neha Bhasin, Deepa Manwani, Sophie Lanzkron, Julie Kanter Nov 2025

National Alliance Of Sickle Cell Centers Consensus Recommendations On Sickle Cell Disease Health Maintenance: A Consensus Statement, Seethal A. Jacob, Melissa Frei-Jones, Sana Saif-Ur-Rehman, Monica L. Hulbert, Andrew R. W. O'Brien, Crawford Strunk, Anthony Villella, Ravi Talati, Amma Owusu-Ansah, Francis Coyne, Patrick T. Mcgann, Parul Rai, Robin Miller, Angeli Rampersad, Vishwas Sakhalkar, Neha Bhasin, Deepa Manwani, Sophie Lanzkron, Julie Kanter

Cardeza Foundation for Hematologic Research

IMPORTANCE: The most common inherited blood disorder in the world, sickle cell disease (SCD) is a known global health concern. While survival of children into adulthood has improved significantly over the last few decades in high-resource countries, substantial gaps in care standards and limited practice harmonization persist.

OBJECTIVE: To provide up-to-date recommendations for preventive care and treatment of all people living with SCD and its related comorbidities.

EVIDENCE REVIEW: As part of the National Alliance of Sickle Cell Centers (NASCC), 41 pediatric and adult sickle cell disease experts developed consensus standards and recommendations based on available evidence and expert consensus …


Educational Policies Committee Agenda November 6, 2025, Utah State University Nov 2025

Educational Policies Committee Agenda November 6, 2025, Utah State University

Educational Policies Committee

  • Approval of Minutes - October 2, 2025
  • Subcommittee Reports
  • Curriculum Subcommittee
  • Academic Standards Subcommittee
  • General Education Subcommittee
  • Other Business
  • Adjourn: 4:00 pm


Condition-Specific Growth Charts For Children With Alagille Syndrome., Koen Huysentruyt, Shannon M. Vandriel, Mathieu Roelants, David A. Piccoli, Kathleen M. Loomes, Elizabeth B. Rand, Noelle H. Ebel, Jeffrey A. Feinstein, Irena Jankowska, Piotr Czubkowski, Dorota Gliwicz-Miedzinska, Emmanuel M. Gonzales, Emmanuel Jacquemin, Jérôme Bouligand, Saul J. Karpen, Rene Romero, Henry C. Lin, Björn Fischler, Henrik Arnell, Li-Ting Li, Jian-She Wang, Rima Fawaz, Silvia Nastasio, Kyung Mo Kim, Seak Hee Oh, Lorenzo D'Antiga, Emanuele Nicastro, Ryan T. Fischer, Susan M. Siew, Michael Stormon, Chatmanee Lertudomphonwanit, Winita Hardikar, Sahana Shankar, James E. Squires, Shikha S. Sundaram, Catherine Larson-Nath, Deirdre A. Kelly, Jane Hartley, Pinar Bulut, M Kyle Jensen, Catalina Jaramillo, Amin J. Roberts, Helen M. Evans, Étienne M. Sokal, Tanguy Demaret, Henkjan J. Verkade, Richard J. Thompson, Bettina E. Hansen, Tim J. Cole, Binita M. Kamath, Dominique Debray, Florence Lacaille, Jernej Brecelj, Nehal M. El-Koofy, Mohamed A. Elmonem, Way Seah Lee, Maria Camila Sanchez, Maria Lorena Cavalieri, Christina Hajinicolaou, Kathleen B. Schwarz, Elisa Carvalho, Nathalie Rock, Wikrom Karnsakul, Ruben E. Quiros-Tejeira, Seema Alam, Gabriella Nebbia, Yael Mozer-Glassberg, Pamela L. Valentino, Ermelinda Santos-Silva, Zerrin Önal, Antal Dezsofi-Gottl, Melina Melere, María Legarda Tamara, John Eshun, Aglaia Zellos, Giuseppe Indolfi, Maria Rogalidou, Niviann Blondet, Pier Luigi Calvo, Marisa Beretta, Andréanne N. Zizzo, Cigdem Arikan, Mureo Kasahara, Nanda Kerkar, Amal A. Aqul, Victorien M. Wolters, Raquel Borges Pinto, Jesus Quintero Bernabeu, Jennifer Garcia, Sabina Wiecek, Christos Tzivinikos, Quais Mujawar, Carolina Jimenez-Rivera, Cristina Molera Busoms, Cristina Gonçalves, Luis Bujanda, Global Alagille Alliance (Gala) Study Group Nov 2025

Condition-Specific Growth Charts For Children With Alagille Syndrome., Koen Huysentruyt, Shannon M. Vandriel, Mathieu Roelants, David A. Piccoli, Kathleen M. Loomes, Elizabeth B. Rand, Noelle H. Ebel, Jeffrey A. Feinstein, Irena Jankowska, Piotr Czubkowski, Dorota Gliwicz-Miedzinska, Emmanuel M. Gonzales, Emmanuel Jacquemin, Jérôme Bouligand, Saul J. Karpen, Rene Romero, Henry C. Lin, Björn Fischler, Henrik Arnell, Li-Ting Li, Jian-She Wang, Rima Fawaz, Silvia Nastasio, Kyung Mo Kim, Seak Hee Oh, Lorenzo D'Antiga, Emanuele Nicastro, Ryan T. Fischer, Susan M. Siew, Michael Stormon, Chatmanee Lertudomphonwanit, Winita Hardikar, Sahana Shankar, James E. Squires, Shikha S. Sundaram, Catherine Larson-Nath, Deirdre A. Kelly, Jane Hartley, Pinar Bulut, M Kyle Jensen, Catalina Jaramillo, Amin J. Roberts, Helen M. Evans, Étienne M. Sokal, Tanguy Demaret, Henkjan J. Verkade, Richard J. Thompson, Bettina E. Hansen, Tim J. Cole, Binita M. Kamath, Dominique Debray, Florence Lacaille, Jernej Brecelj, Nehal M. El-Koofy, Mohamed A. Elmonem, Way Seah Lee, Maria Camila Sanchez, Maria Lorena Cavalieri, Christina Hajinicolaou, Kathleen B. Schwarz, Elisa Carvalho, Nathalie Rock, Wikrom Karnsakul, Ruben E. Quiros-Tejeira, Seema Alam, Gabriella Nebbia, Yael Mozer-Glassberg, Pamela L. Valentino, Ermelinda Santos-Silva, Zerrin Önal, Antal Dezsofi-Gottl, Melina Melere, María Legarda Tamara, John Eshun, Aglaia Zellos, Giuseppe Indolfi, Maria Rogalidou, Niviann Blondet, Pier Luigi Calvo, Marisa Beretta, Andréanne N. Zizzo, Cigdem Arikan, Mureo Kasahara, Nanda Kerkar, Amal A. Aqul, Victorien M. Wolters, Raquel Borges Pinto, Jesus Quintero Bernabeu, Jennifer Garcia, Sabina Wiecek, Christos Tzivinikos, Quais Mujawar, Carolina Jimenez-Rivera, Cristina Molera Busoms, Cristina Gonçalves, Luis Bujanda, Global Alagille Alliance (Gala) Study Group

Manuscripts, Articles, Book Chapters and Other Papers

IMPORTANCE: Different degrees of growth delay have been reported in children with Alagille syndrome (ALGS), yet these patients are routinely evaluated using standard growth charts.

OBJECTIVE: To develop condition-specific growth charts for ALGS using modern statistical approaches.

DESIGN, SETTING, AND PARTICIPANTS: This case series used data from the international, multicenter Global Alagille Alliance (GALA) study accrued between May 14, 2018, and March 20, 2023. Children born at full term between January 1, 1997, and August 31, 2019, with a clinically and/or genetically confirmed ALGS diagnosis and their native liver were included. Data from children with a known history of prematurity …


Muscle Fatigue Arising Intrinsically From Sur2- But Not Kir6.1-Dependent Gain-Of-Function In Cantu Syndrome Mice, Rosa Scala, Maya Mukadam, Yuezhou Chen, Courtney Frazier, Nathaniel W York, Robert C Tryon, Gretchen A Meyer, Colin G Nichols Nov 2025

Muscle Fatigue Arising Intrinsically From Sur2- But Not Kir6.1-Dependent Gain-Of-Function In Cantu Syndrome Mice, Rosa Scala, Maya Mukadam, Yuezhou Chen, Courtney Frazier, Nathaniel W York, Robert C Tryon, Gretchen A Meyer, Colin G Nichols

2020-Current year OA Pubs

Cantu syndrome (CS) is a rare disease caused by gain-of-function (GOF) mutations of Kir6.1 or SUR2 subunits of ATP-sensitive potassium (KATP) channels. CS patients with SUR2 and Kir6.1 variants display a similar constellation of symptoms, including muscle weakness and fatigue. The effects of CS mutations on skeletal muscle KATP channels, and any consequent direct effects on contractility, are currently unclear. Here, we used two knock-in mouse models of CS, respectively, carrying GOF mutations Kir6.1[V65M] or SUR2[A478V], to assess KATP channel properties and contractility in isolated fast-twitch extensor digitorum longus (EDL) and slow-twitch soleus (SOL) muscles. Electrophysiological recordings in isolated myofibers …


Physical Activity And Molecular Subtypes Of Colorectal Cancer: A Pooled Observational Analysis And Mendelian Randomization Study, Christos V Chalitsios, Yin Cao, Et Al. Nov 2025

Physical Activity And Molecular Subtypes Of Colorectal Cancer: A Pooled Observational Analysis And Mendelian Randomization Study, Christos V Chalitsios, Yin Cao, Et Al.

2020-Current year OA Pubs

BACKGROUND: Physical activity is associated with lower colorectal cancer (CRC) risk, but its association with molecular subtypes defined by genetic and epigenetic alterations of the disease is unclear. Such information may enhance the understanding of the mechanisms related to the benefits of physical activity.

METHODS: Pooled observational (cases: n = 5386; controls: n = 6798; studies n = 5) and genome-wide association data (cases: n = 8178; controls: n = 10 472; studies n = 5) were used. We used multivariable logistic regression models and Mendelian randomization to assess the association between physical activity and the risk of CRC subtypes …


Availability, Healthiness And Sodium Content Of Packaged And Unpackaged Foods And Beverages In Nigeria: A Cross-Sectional Study, Adedayo E Ojo, Erica L Jamro, Iyer Guhan, Mark D Huffman, Et Al. Nov 2025

Availability, Healthiness And Sodium Content Of Packaged And Unpackaged Foods And Beverages In Nigeria: A Cross-Sectional Study, Adedayo E Ojo, Erica L Jamro, Iyer Guhan, Mark D Huffman, Et Al.

2020-Current year OA Pubs

BACKGROUND: Nigeria is experiencing a growing burden of diet-related non-communicable diseases, particularly hypertension and cardiovascular disease, largely driven by high sodium intake and poor diet quality. Unhealthy dietary patterns characterized by excessive sodium, sugars, and unhealthy fats, and low intake of essential nutrients contribute to approximately 31% of global deaths annually. However, there is limited data on the sodium content and nutritional quality of foods in Nigerian markets. This study assessed and compared the availability, healthiness, and sodium content of packaged and unpackaged foods in Nigerian markets.

METHODS: From August 2022 to December 2022, we collected and compared nutrition data …