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Articles 37021 - 37022 of 37022
Full-Text Articles in Entire DC Network
Ecobuoys For Scalable Oceanography, Anuscheh Nawaz, Michael Steele, Ruth Branch, David Burnett, Kuotian Liao, Mallory Parker, Eleftheria Roumeli
Ecobuoys For Scalable Oceanography, Anuscheh Nawaz, Michael Steele, Ruth Branch, David Burnett, Kuotian Liao, Mallory Parker, Eleftheria Roumeli
Electrical and Computer Engineering Faculty Publications and Presentations
An approach to scalable surface-drifting buoys is needed to enable the high spatial and temporal resolution of oceanographic data that the science and meteorological communities are asking for. With the number of active buoys predicted to increase by a factor of 100 or more, the impact on the environment becomes even more important. Here, we present a pathway to a scalable and sustainable generation of buoys. We identify the main criteria to be used when developing such buoys to be low cost, with reliable data and neutral or even positive environmental impact. For each buoy subsystem—hull, electronics, energy generation and …
Finite Element Simulation Of Interstitial–Lymphatic Fluid Flow And Nanodrug Transport In A Solid Tumor: An Intratumoral Injection Approach, Gobinda Debnath, Buddakkagari Vasu, Rama Subba Reddy Gorla
Finite Element Simulation Of Interstitial–Lymphatic Fluid Flow And Nanodrug Transport In A Solid Tumor: An Intratumoral Injection Approach, Gobinda Debnath, Buddakkagari Vasu, Rama Subba Reddy Gorla
Faculty Publications
Objective: This study presents a mathematical model and finite element simulations to investigate interstitial fluid flow and nanodrug transport in a solid tumor, incorporating transvascular exchange, convection–diffusion–reaction dynamics, and intratumoral injection mechanisms. Impact Statement: Optimizing nanodrug distribution remains a critical challenge in cancer therapy. The proposed model advances nanomedicine by enhancing the mechanistic understanding of nanodrug transport in a solid tumor. Introduction: Cancer, a global threat, often manifests as solid tumors driven by uncontrolled cell growth. The heterogeneous microenvironment, lymphatic drainage, nano-bio interactions, and elevated interstitial fluid pressure (IFP) hinder effective nanodrug delivery. Nanoparticle (NP)-based drug delivery systems offer a …