Digital Commons Network^™

Ribosome Hibernation In Mycobacterium Abscessus And Its Effect On Antibiotic Resistance, Ryan Treen

Electronic Theses & Dissertations (2024 - present)

Non-tuberculosis mycobacteria (NTM) represent a diverse repertoire of species, most of which are ubiquitous in the environment. Some NTM species, such as Mycobacterium abscessus, can cause life-threatening infections in people with underlying medical conditions. The clinical incidence of such infections is on the rise, posing an emerging threat to public health. M. abscessus is characterized by intrinsic and acquired antibiotic resistance, complicating treatment strategies. Most chemotherapeutic approaches for M. abscessus infection target the bacterial ribosome, necessitating a better understanding of the physiological processes which confer this resistance. Multiple mycobacterial species respond to zinc-limiting conditions by inducing remodeling and hibernation …

Managing Artificial Intelligence In The Public Sector: Adoption, Implementation, And Results, Tzuhao Chen

Electronic Theses & Dissertations (2024 - present)

With the rapid advancement of artificial intelligence (AI), governments around the world are increasingly exploring how AI can enhance decision-making and improve public service delivery. A growing body of research has examined governmental use of AI, offering insights into several key areas: (1) domains of application, (2) potential benefits and risks of AI initiatives, and (3) adoption and implementation processes, including critical determinants and results. However, two significant gaps remain in the literature. First, there is limited understanding of how the unique characteristics of AI may transform government service delivery and internal operations. Second, while many studies on AI-related managerial …

Characterization Of Corticotropin Releasing Factor Receptor 2 In Stress-Regulating Regions Of The Mouse Brain, Jennifer J. Lafrican

Electronic Theses & Dissertations (2024 - present)

Sex differences in the morphology of the brain are thought to underlie the sex differences we see in anxiety and depression, where women are twice as likely to be diagnosed when compared to men. Stress, or a disruption to homeostasis, can exacerbate these mood disorders. Corticotropin releasing factor (CRF), and its receptors, play an important role in regulating the stress response. Binding of CRF with CRFR2 has been shown to reduce behavioral and neuroendocrine stress responses, yet whether there are sex differences in CRFR2 expressing neurons and stress-induced activation of these neurons in mice is unknown, in part due to …

Grandparenthood And Psychological Well-Being Of Middle-Aged And Older Adults: Multigenerational Family Relationships In China, Dandan Zhao

Electronic Theses & Dissertations (2024 - present)

This dissertation examines whether and how experiences of grandparenthood—including becoming a grandparent, providing grandchild care, living with grandchildren, and exchanging intergenerational support—affect the well-being of middle-aged and older adults in China. Drawing on data from the China Health and Retirement Longitudinal Study (CHARLS, 2011–2018), a nationally representative survey of Chinese adults aged 45 and older, the study employs Ordinary Least Squares (OLS) regression and random effects models to investigate the associations between multigenerational family relationships and depressive symptoms among this population.

There is limited evidence that the transition to grandparenthood itself has a significant impact on psychological well-being. However, patterns …

Investigating Post-Adoption Abandonment Of Mental Health Mobile Applications Among Young Adults, Donald Harris

Electronic Theses & Dissertations (2024 - present)

The rising prevalence of mental health issues among young adults has driven increased interest in Mental Health Mobile Applications (MHMAs), which offer accessible and cost-effective solutions to traditional barriers such as financial limitations, stigma, and restricted healthcare access. Despite their promise, MHMAs frequently experience high rates of attrition and abandonment, significantly limiting their long-term effectiveness. Employing a mixed-methods, multi-stage research design, this dissertation explores the determinants of MHMA abandonment among young adults, emphasizing the interplay between technological inhibitors and enablers, individual user characteristics, and the mediating roles of user satisfaction and perceived usefulness.

Study 1 utilized quantitative text analysis, including …

Jedi Mind: Student And Teacher Perceptions Of Justice, Equity, Diversity, And Inclusion, Jessica W Coles Gray

Electronic Theses & Dissertations (2024 - present)

This study uses the Panorama Equity and Inclusion Survey as a measurement tool to examine the perceptions of equity and inclusion among teachers and students in a K-12 educational setting. Grounded in critical race theory, this research employs a QUANT-CRIT mixed methods approach to illuminate systemic inequities and amplify the voices of historically marginalized groups. A review of the existing literature reveals persistent disparities in educational experiences and outcomes for students and teachers of color, underscoring the need for a dual focus on both quantitative patterns and qualitative narratives. The study addressed two primary research questions: (1) What are teachers’ …

The Psychological Impacts Of Homeland Havoc Among First-Generation Raised Americans: An Interpretive Phenomenological Analysis, Raneem Kurzum

Electronic Theses & Dissertations (2024 - present)

The current study explored the psychological experiences of first-generation raised U.S. citizens whose ancestral homelands are affected by ongoing or recent havoc. First-generation raised Americans are defined as the first-generation to be born in the U.S. or those who immigrated to the U.S. during infancy (less than two years of age). While research on trauma, resilience, and identity has previously addressed collective and intergenerational responses within culturally homogenous groups, few studies have examined the cross-cultural psychological impact of homeland turmoil among diverse diasporic populations living in the U.S.

Using Interpretive Phenomenological Analysis (IPA), this qualitative study employed semi-structured individual interviews …

Street Outreach And Reentry: The Role Of Community Violence Intervention In The Reintegration Of Returning Citizens, Hilary Jackl

Electronic Theses & Dissertations (2024 - present)

Amidst ongoing efforts to reduce the nation’s prison population, as well as calls to defund the police and invest in civilianized public safety strategies following the murder of George Floyd, community-based violence intervention (CVI) strategies have been increasingly recognized as a critical means by which to ameliorate the United States’ enduring gun violence problem without exacerbating the harms of overpolicing and mass incarceration. However, most contemporary CVI research has assessed program impacts on neighborhood rates of gun violence and has produced conflicting findings, leading scholars to call for the need to examine a wider range of program-related functions and outcomes. …

Exploring Identity And Belonging Through Housing Pathways: Resettlement Experiences Of Female Ukrainian Refugees, Stephanie M. Duncan

Electronic Theses & Dissertations (2024 - present)

Background: This dissertation examines the resettlement experiences of female Ukrainian refugees in Germany following the escalation of the Russia-Ukraine conflict in 2022, which displaced over 8.5 million Ukrainians, including 1.2 million to Germany by April 2024. Focusing on Munich, the study explores the interplay of housing pathways, identity, and belonging, emphasizing gendered challenges faced by women, particularly single mothers and caregivers, navigating trauma, systemic barriers, and cultural adaptation. Organized into three articles, this work employs a social justice lens to address structural barriers, such as discriminatory housing markets, economic exclusion, and limited access to resources, which disproportionately impact marginalized women, …

Author-Centered Approaches In Ela Instruction: A Multiple Case Study Of Secondary English Teachers, Jennifer M. Lockhart Mchugh

Electronic Theses & Dissertations (2024 - present)

Literary authors are often neglected in secondary ELA (English Language Arts) literary instruction. Teachers are unsure how to teach about the author and how much time to spend on establishing the context for the text when the goal is to “cover” a variety of literary texts as part of a planned curriculum during the school year. Acknowledging the role of authors’ intentions as well as their experiences and aesthetic decisions in the production of literature may provide new entry points into literary texts for students. This multiple-case study of secondary English teachers and their high school students in a “bounded …

Investigating Rna Dysfunction Of Inherited Neuromuscular And Neurodevelopmental Disease, Jacob H. Schroader

Electronic Theses & Dissertations (2024 - present)

ITPase deficiency is a rare but fatal, autosomal recessive enzyme deficiency involving encephalopathy, microcephaly, congenital cataracts, hypotonia, developmental delay, and dilated cardiomyopathy. Within a decade since the original description of the severe form in humans, there are huge gaps in the field regarding the underlying molecular mechanisms driving pathogenesis resulting from ITPase deficiency. Past studies have focused on characterization of the organism level ITPase-deficient phenotype, but the molecular and cellular characterization remains to be fully described. Due to the biochemical function and established biological role of the ITPase enzyme, investigation into the consequences of inosine accumulation and misincorporation into RNA …

Photoswitchable Inhibitors Of Eaat3, Karly Suhr

Electronic Theses & Dissertations (2024 - present)

Azobenzene is a photoswitchable molecule known for its high conversion yield and repeatability. The inclusion of an azobenzene moiety with a known inhibitor of your target of interest allows for greater study of function as well as potential therapies. Three derivatives were designed from azobenzene and known inhibitor of EAATs, TBOA, to synthesize photoswitchable inhibitors of EAATs. Further investigation into the function of EAATs and development of a specific inhibitor for EAAT3, an important glutamate transporter in the brain required for proper function, can then be conducted. Photoisomerization studies on the derivatives were conducted using UV/vis spectroscopy and NMR spectroscopy. …

Investigating The Perceived Masculinity And Femininity Of Nonbinary Individuals, Dante D. Sasso Jr.

Electronic Theses & Dissertations (2024 - present)

Nonbinary individuals identify outside of the typical gender binary of men and women. Existing research has not investigated how nonbinary people are perceived in terms of masculinity and femininity. We hypothesized that nonbinary individuals would be perceived as less masculine than men and less feminine than women, while also being perceived as overall more feminine than masculine. Participants viewed a researcher-generated social media profile. The primary experimental manipulation involved varying the pronouns listed in the profile biography, denoting a man (he/him), woman (she/her), or nonbinary person (they/them). Participants rated how masculine and feminine they perceived the target person to be, …

Improving Generalizability In Image Manipulation Detection, Zhenfei Zhang

Electronic Theses & Dissertations (2024 - present)

Image manipulation detection (IMD) aims to determine whether an image has been tampered with and to identify the manipulated regions. These capabilities have become increasingly important with the rapid advancement of media editing and generation technologies, such as Photoshop and generative AI methods, which underscore the need for robust tools for media authentication. Although current state-of-the-art (SoTA) methods achieve strong results on common manipulation types, such as splicing, copy-move, and removal, they often struggle to generalize to manipulation types not represented in the training data. Consequently, their real-world applicability remains limited, with performance degrading significantly in practical scenarios.

In this …

Officers’ Perceptions Of Body-Worn Cameras: An Exploratory Study Of Small Police Departments In Upstate New York, Stefan A. Dela Riva

Electronic Theses & Dissertations (2024 - present)

The aim of this exploratory study is to examine how police officers perceive the impact of body-worn cameras (BWCs) on their use of discretion when communicating with members of the public. In this context, “discretion” refers to an officer’s authority to make independent judgments while enforcing the law; deciding whether to issue a warning, make an arrest, or resolve an incident informally when legality permits. To understand officers’ opinions, a cross-sectional, quantitative online survey was distributed to various police departments and sheriff’s offices in upstate New York. Participants completed a series of Likert-style survey items addressing their general views on …

Interfacing Neural Models: Biocompatibility And Fabrication Of A Flexible, Self-Folding Microelectrode Array, Fernando A. Pesantez Torres

Electronic Theses & Dissertations (2024 - present)

Neurodegenerative diseases pose a formidable challenge in modern medicine, necessitating the development of advanced research tools that can elucidate their complex pathophysiology. Recent advancements in neurodegenerative disease research have led to the development of three-dimensional (3D) neurodegenerative organoids using human induced pluripotent stem cells (hiPSCs). These organoids closely mimic human brain architecture and functionality, providing a valuable tool for understanding complex diseases. Additionally, the ability to generate and study brain organoids consistently and in large quantities holds potential for a controlled in vitro setting and high-throughput drug screening. However, these models are complex systems requiring specialized maintenance, analysis, and manipulation …

Explaining Mass Shooting Motivations: A Case Survey Analysis Of Us Mass Shootings (2006-2024), Isaiah H. Harris

Electronic Theses & Dissertations (2024 - present)

Research on the motivations behind mass shootings remains inconclusive as these events often lack a singular or explicit cause. The motivations of mass shooters are complex, shaped by the interplay of psychological, social, and ideological factors. While some attacks are clearly driven by extremist beliefs, others appear to stem from less defined forces such as depravity or sadistic intent. Existing typologies, such as Langman’s (2009) analysis of school shooters, offer valuable insight but are limited in scope. This study expands upon previous research by examining U.S. mass shootings from 2006 to 2024 to determine whether such events are more frequently …

Welfare States And Imprisonment Rates: Revisiting The Study Of Public Assistance And Punishment In The United States, Stefan Ivanov

Electronic Theses & Dissertations (2024 - present)

In the past fifty years, the United States has seen significant changes in both the criminal legal system and the welfare state. The incarceration rate surged by 475% from 1972 to 2007, driven by state-level decisions about criminal legal policy and disproportionately affecting Black Americans. Simultaneously, welfare programs became less generous, especially for those deemed “undeserving.” A long line of social science scholarship emphasizes that these two major social institutions—the welfare state and the carceral state—must be considered as complementary and alternative methods of managing marginalized groups. Quantitative research often confirms these claims, finding a durable inverse relationship between welfare …

Pathways To Disclosure And Treatment Among Individuals With An Attraction To Minors, Theodore Jackson

Electronic Theses & Dissertations (2024 - present)

Child sexual abuse prevention is a significant social concern in the United States and internationally. While there have been some successful efforts to reduce recidivism risk among individuals who have committed sexual offenses, we fall short when preventing first time offenses. Therefore, looking at ways to provide treatment to those who are more at-risk for a first offense seems like a potential solution to this problem. One such relevant risk-factor is attraction to minors. This study is a qualitative examination using Interpretive Phenomenological Analysis of how people who are attracted to minors make the decision to disclose their attraction, seek …

A Social Exchange Perspective On Attentiveness As A Resource In Newcomer Relationship Development And Assimilation, Huy Q. Le

Electronic Theses & Dissertations (2024 - present)

My dissertation investigates the role of social relationships in newcomer socialization within organizations, emphasizing the importance of extra-role conversations in building affective trust and facilitating integration. I hypothesize that while attention to work-related tasks is crucial, engaging in extra-role conversations with supervisors and co-workers fosters affective trust, a key factor in socialization. I integrate social exchange theory, proposing that attention acts as a socioemotional resource exchanged in social interactions, leading to stronger affective trust and ultimately socialization outcomes. These informal interactions help newcomers adopt organizational values and integrate into social groups. I test my hypotheses using longitudinal archival data collected …

Climate Change In The Local News: The Role Of Community Characteristics In Shaping Themes And Diversity, Hyerim Jo

Electronic Theses & Dissertations (2024 - present)

Despite widespread recognition of climate change and its localized impacts, research on how local media cover this topic remains limited. The first study of this dissertation analyzes 15,788 opinion articles published from 2013 to 2020 by 391 local newspapers in the United States to examine their volume, topics, and thematic emphases. Using automated text analysis methods, including Latent Dirichlet Allocation (LDA) and Analysis of Topic Model Networks (ANTMN), the study identifies 11 topics and three overarching themes. Findings indicate that the volume, topics, and themes evolved over time, likely influenced by the severity of climate-induced hazards and political and socioeconomic …

Intention-Setting Among Recreational Psychedelic Users: Associated Acute Effects And Changes In Well-Being, Zi Ling Fiona Low

Electronic Theses & Dissertations (2024 - present)

Psychedelic intentions play an important role in shaping acute psychedelic experiences and influencing long-term outcomes. Limited existing literature suggests that different types of intentions are linked to acute experiences and outcomes in varying ways. However, data on the types of intentions set by recreational users remain scarce, and their effects lack clarity. This study investigates intention-setting practices among recreational psychedelic users, aiming to establish a taxonomy of intentions in naturalistic use contexts and clarify user perspectives on the impact of intention-setting. We also examine how domain-specific intentions correlate with acute psychedelic effects and changes in well-being. Finally, we test a …

A Theoretical And Empirical Adaptation Of Signaling Theory For Digital Communication: Examining Organizational Brand Identity And Credibility, Victoria Barbeisch

Electronic Theses & Dissertations (2024 - present)

This dissertation adapts signaling theory for digital communication and tests its relevance in strategic communication, specifically concerning unobservable organizational traits like brand identity values. Signaling theory explains how parties with unequal information (senders/signalers and receivers) use signals to bridge knowledge gaps and influence decision-making. While rooted in biology and economics, its application in computer-mediated communication (CMC) remains limited. This research addresses this gap through two primary aims. Aim 1 presents the first comprehensive theoretical adaptation of signaling theory for digital communication, consolidating fragmented research across multiple disciplines. Aim 2 investigates the theory's relevance in strategic communication related to unobservable brand …

A Structurationally Informed View Of Emergency Medical Services Professionals’ Work-Related Communication And Behaviors While Off Duty, Susan J. Burnett

Electronic Theses & Dissertations (2024 - present)

Work-life interrelationships and boundaries are common areas of study in communication research. While some scholars maintain that the domains of work and personal lives and their boundaries are static and exist in designated times and spaces, others argue that domains are constructed around situated contexts and through the performance of situated activities that not only produce a time and place for the domain but call upon enactment of an identity appropriate for managing the domain and the boundaries around it. The people who work in emergency medical services (EMS), emergency medical services professionals (EMSPs) face special challenges in managing work-life …

Epitaxial Quantum Dot Scintillators With Monolithic Photodetector Integration: Physics, Fabrication And Characterization Of Materials And Devices, Allan Oreave Minns

Electronic Theses & Dissertations (2024 - present)

This dissertation discloses the physics, fabrication, and characterization of high-performance scintillator detectors based on epitaxial InAs quantum dots (QDs) in GaAs. The detector crystals grown include monolithically integrated In_0.35GaAs photodetectors with Al_0.92-0.6In_0.03-0.35Ga_0.05As metamorphic buffer layers (MBL). A device fabrication process was developed for the lithographic patterning, chemical etching, contact metallization and readout integration of materials grown by means of molecular beam epitaxy (MBE) on 3-inch GaAs (001) wafers. Low capacitance integration with readout electronics was achieved through wire bonds to custom printed circuit boards (PCBs) with commercial components.

The relationship between device …

First-Gen Latinx/Afro-Latinx And Complex: Keeping Resilient Responses On Shuffle, Tibisay I. Hernandez

Electronic Theses & Dissertations (2024 - present)

This qualitative study examined the racialized experiences of first-generation Latinx and Afro-Latinx students in higher education. Fourteen participants engaged in pláticas, semi-structured interviews, and focus groups to reflect on how their identities, race, and institutional dynamics shaped their collegiate journeys. The study examined how these students navigated both personal and institutional settings, revealing the emergence of tensions around belonging, authenticity, and cultural responsibility in everyday interactions. Using Latino Critical Race Theory (LatCrit) alongside Multidimensional Identity Negotiation Theory (MINT) and Co-Cultural Communication Theory (CCCT), this study developed an emergent framework—the Resilient Response Model—to better understand how students respond to complex identity …

Divided By Fear: The Influence Of Political Beliefs On The Perception Of Extremist Groups, Hannah A. Scott

Electronic Theses & Dissertations (2024 - present)

Acts of violent extremism and support for political violence have increased in the United States over the past decade. Previous studies have primarily focused on the differences in risk perception between White Supremacists and Islamic Extremists/Jihadists, neglecting other ideological movements. This study utilizes data from the fifth wave of the Chapman Survey of American Fears and employs ordinal logistic regression to compare the fear of seven different extremist groups and movements: Islamic Extremists/Jihadists, the Militia/Patriot Movement, White Supremacists, Extreme Environmentalists, Extreme Animal Rightists, Anti-Immigration Groups, and ANTIFA. The findings reveal notable differences across political parties (Democrats, Republicans, and Independents) and …

Concurrent Parasympathetic Synchrony In Romantic Couples Exposed To Childhood Maltreatment Subtypes, Kate L. Senich

Electronic Theses & Dissertations (2024 - present)

Early responsive caregiving hones children’s physiological systems and subsequently supports social interactions (Feldman, 2007; Porges 2001; Steelman et al, 2002). Conversely, mis-attuned interactions with caregivers, such as exposure to maltreatment subtypes, might hinder social engagement capacities at both behavioral and biological levels (Kim & Cicchetti, 2004; Sheridan & McLaughlin et al., 2014). These early adverse influences endure across development and can affect behavioral and physiological interactions with romantic partners (Mayo et al., 2021; River et al., 2020; Zamir, 2022). Specifically, temporally coordinated patterns of physiological responses between partners (i.e., synchrony) are linked with important relationship behaviors, including conflict behaviors …

Embracing The Unmanageable: The Critique Of The Everyday And The Postwar Condition In Wallace Stevens’ And Robert Duncan’S Works Circa 1950, Kazuma Morita

Electronic Theses & Dissertations (2024 - present)

My thesis is designed as an investigation of the ethical and political implications of the everyday in postwar American poetry. While recent scholarship of everyday life studies has clarified the centrality of the everyday or the ordinary to modernism and postwar literature, it does not elaborate enough on the impact of the political condition on literary expressions of everyday life in post-1945 period. Given U.S. military’s infiltration into everyday life of people living inside and outside the country after World War II, it is an important task to spotlight the way American postwar poets tackled U.S. war culture through their …

Worldbuilding A Queer Before: D&D As A Neomedievalism For A Modern Age, Brianna M. Thompson

Electronic Theses & Dissertations (2024 - present)

Dungeons & Dragons (D&D) has had countless participants and audience members in the course of its over fifty-year existence. It has also been the subject of several studies that attempt to capture its unique form of performative play. Yet, there has been a scarcity of scholarship on how D&D acts as a neomedievalism and how that can offer a queer kind of opportunity to its players, allowing them to find a place in a past that is historically inaccessible and yet endlessly in the process of being (re)imagined. Using an interweaving of archival theory with queer and performance studies, particularly …