Open Access. Powered by Scholars. Published by Universities.®

Digital Commons Network™

Open Access. Powered by Scholars. Published by Universities.®

2025

Discipline
Institution
Keyword
Publication
Publication Type
File Type

Articles 36001 - 36030 of 36933

Full-Text Articles in Entire DC Network

Analysis Of Cytokine Data In A Case-Control Study Of Me/Cfs, Navya Amaratunga Jan 2025

Analysis Of Cytokine Data In A Case-Control Study Of Me/Cfs, Navya Amaratunga

Electronic Theses & Dissertations (2024 - present)

This study investigated the role of cytokines in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS), a debilitating multi-system disease with unknown etiology. Using data from a case-control study (60 cases, 61 controls) previously collected by Dr. Roxana Moslehi’s lab, serum levels of 48 cytokines were analyzed. Statistical analyses, including T-tests, Wilcoxon Rank Sum tests, and logistic regression (unadjusted and adjusted for medication use), were performed to identify differences between cases and controls.

Results revealed a statistically significant difference in mean Fractalkine levels between cases and controls (p=0.031). Borderline significant differences were also observed for IL-6 (p=0.046) and MIP-1α (p=0.046). Unadjusted logistic regression …


Diversity, Genomics And Antimicrobial Resistance Of Coagulase-Negative Staphylococcus: A Literature Review, Kathleen Okeefe Jan 2025

Diversity, Genomics And Antimicrobial Resistance Of Coagulase-Negative Staphylococcus: A Literature Review, Kathleen Okeefe

Electronic Theses & Dissertations (2024 - present)

Members of the gram-positive bacterial genus Staphylococcus have historically been classified into coagulase-positive Staphylococcus (CoPS) and coagulase-negative Staphylococcus (CoNS). This classification is based on the ability of clotting of plasma by the coagulase enzyme, which converts fibrinogen to fibrin. CoNS species are ubiquitous commensals that frequently colonize the skin and mucosal surfaces. They are also opportunistic pathogens implicated in many human and animal infections. The evolutionary history of CoNS has generally been overlooked because of the historical lack of recognition for their clinical importance and poor taxonomic sampling. They are often perceived as being less or non-pathogenic, especially compared to …


Antibody-Induced Multicellular Behaviors Of Salmonella Typhimurium, Samantha K. Lindberg Jan 2025

Antibody-Induced Multicellular Behaviors Of Salmonella Typhimurium, Samantha K. Lindberg

Electronic Theses & Dissertations (2024 - present)

Salmonella enterica is a globally distributed bacterial pathogen that is commonly acquired through consumption of contaminated food and water. The enterica subspecies includes over 1500 unique subvariants, or serovars, that are classified by antigen presentation. Due to its global environmental prevalence, broad host range, and increasing pathogenicity, serovar Typhimurium is of particular concern for human and animal health, as well as food safety. Once in the gastrointestinal tract, Salmonella Typhimurium (STm) exploits host immune mechanisms, implements an arsenal of virulence factors, and outcompetes the microbiota to invade the intestinal epithelium. While STm infections are generally self-limiting and relatively mild, emerging …


Weaving A Tapestry Of Community Based Child Trafficking Interventions In High-Trafficking Incidence Areas In Ghana, Crispin Mbamba Jan 2025

Weaving A Tapestry Of Community Based Child Trafficking Interventions In High-Trafficking Incidence Areas In Ghana, Crispin Mbamba

Electronic Theses & Dissertations (2024 - present)

Background: This dissertation addresses the urgent issue of child trafficking in high-incidence areas of Ghana, where sociocultural, economic, and structural factors sustain and exacerbate this complex social challenge. The rationale for the study is grounded in the need for a holistic understanding of child trafficking beyond traditional justice-based approaches. The research emphasizes the necessity of community-led interventions informed by local cultural norms and protective values that have been largely unexplored in the Ghanaian context. Specifically, this dissertation applies an integrative approach, rooted in the Ubuntu philosophy, to explore community interdependence as a central component of sustainable anti-trafficking interventions.

Methods: …


Characterization Of Adaptive Quorum Sensing In Pseudomonas Aeruginosa, Kayla Simanek Jan 2025

Characterization Of Adaptive Quorum Sensing In Pseudomonas Aeruginosa, Kayla Simanek

Electronic Theses & Dissertations (2024 - present)

Pseudomonas aeruginosa is an opportunistic pathogen that is highly antibiotic resistant and causes tens of thousands of infections each year. It persists in hospitals by forming biofilms on medical equipment like ventilators and catheters, making it difficult to eradicate. Biofilm formation, among other virulence factors of P. aeruginosa, is regulated through quorum sensing, a mechanism of bacterial communication. Quorum sensing is primarily coordinated through LuxI-R type systems comprised of an autoinducer synthase and receptor, respectively. Canonically, the first system to be expressed is LasI-R, and LasR upregulates the second arm of the quorum sensing network, the RhlI-R system. Research …


“The Culture - I Wish It Were Less Intense And More Joyful And Full Of Life”: A Youth Participatory Action Study On Teen Mental Health And Wellness, Marna Wolak Jan 2025

“The Culture - I Wish It Were Less Intense And More Joyful And Full Of Life”: A Youth Participatory Action Study On Teen Mental Health And Wellness, Marna Wolak

Doctoral Dissertations

Studies indicate that a grave mental health crisis is disproportionately impacting female-identified youth. While school districts have made attempts to address this problem, those most impacted - young people - have frequently found their voices overlooked by adults seeking solutions. Therefore, this Youth Participatory Action Research (YPAR) study, grounded in humanizing and liberatory pedagogy, examines how high school-aged students in an urban school district understand and define their experiences with mental health challenges and suggest strategies and interventions for improved wellness. Two sets of research questions guide this study: 1) Primary questions: What are youth perspectives about how their mental …


Cambio De Código Y Fenómenos Léxicos En Tres Generaciones De Hispanohablantes Dominicanos En Nueva Jersey, Rocio Leguisamon Tolentino Jan 2025

Cambio De Código Y Fenómenos Léxicos En Tres Generaciones De Hispanohablantes Dominicanos En Nueva Jersey, Rocio Leguisamon Tolentino

Electronic Theses & Dissertations (2024 - present)

En Estados Unidos, el contacto prolongado entre el español y el inglés ha generado diversas situaciones de bilingüismo. Sin embargo, históricamente, la comunidad mexicana en el suroeste del país y la comunidad puertorriqueña en el noroeste han sido las más representadas y, por tanto, las más estudiadas (Poplack 1980; Silva-Corvalán 1994; Torres Cacoullos y Travis, 2015; Rodríguez-Ordóñez et al., 2023). Recientemente, las investigaciones sobre el bilingüismo en la comunidad dominicana han ido cobrando más relevancia, debido al rápido incremento de dominicanos en los Estados Unidos. Investigaciones anteriores han propuesto que los dominicanos muestran una alta lealtad al español, y a …


Finite Element Simulation Of Interstitial–Lymphatic Fluid Flow And Nanodrug Transport In A Solid Tumor: An Intratumoral Injection Approach, Gobinda Debnath, Buddakkagari Vasu, Rama Subba Reddy Gorla Jan 2025

Finite Element Simulation Of Interstitial–Lymphatic Fluid Flow And Nanodrug Transport In A Solid Tumor: An Intratumoral Injection Approach, Gobinda Debnath, Buddakkagari Vasu, Rama Subba Reddy Gorla

Faculty Publications

Objective: This study presents a mathematical model and finite element simulations to investigate interstitial fluid flow and nanodrug transport in a solid tumor, incorporating transvascular exchange, convection–diffusion–reaction dynamics, and intratumoral injection mechanisms. Impact Statement: Optimizing nanodrug distribution remains a critical challenge in cancer therapy. The proposed model advances nanomedicine by enhancing the mechanistic understanding of nanodrug transport in a solid tumor. Introduction: Cancer, a global threat, often manifests as solid tumors driven by uncontrolled cell growth. The heterogeneous microenvironment, lymphatic drainage, nano-bio interactions, and elevated interstitial fluid pressure (IFP) hinder effective nanodrug delivery. Nanoparticle (NP)-based drug delivery systems offer a …


A Phase Ib/Ii Trial Of Neoadjuvant Neratinib Added To Standard Therapy In Patients With Her2-Positive Or Hr-Positive/Her2-Negative Inflammatory Breast Cancer (Including Stage Iii And Iv Disease), Bora Lim, Angela Marx, Megumi Kai, Angela Alexander, Roland Bassett, Wencai Ma, Jie Willey, Huiming Sun, Azadeh Nasrazadani, Mohammad M Mohammad, Jianhua Zhang, Anthony Lucci, Susie X Sun, Michael C Stauder, Gary J Whitman, Huong Le-Petross, Vicente Valero, Wendy A Woodward, Rachel M Layman Jan 2025

A Phase Ib/Ii Trial Of Neoadjuvant Neratinib Added To Standard Therapy In Patients With Her2-Positive Or Hr-Positive/Her2-Negative Inflammatory Breast Cancer (Including Stage Iii And Iv Disease), Bora Lim, Angela Marx, Megumi Kai, Angela Alexander, Roland Bassett, Wencai Ma, Jie Willey, Huiming Sun, Azadeh Nasrazadani, Mohammad M Mohammad, Jianhua Zhang, Anthony Lucci, Susie X Sun, Michael C Stauder, Gary J Whitman, Huong Le-Petross, Vicente Valero, Wendy A Woodward, Rachel M Layman

Faculty, Staff and Student Publications

Background: Inflammatory breast cancer (IBC) is rare but aggressive, characterized by the rapid onset of diffuse skin erythema, edema, tenderness, induration, and fast metastasis. Both hormone receptor positive (HR+) and human epidermal receptor 2 positive (HER2+) are associated with inferior response after neoadjuvant systemic therapy (NAST) compared to non-IBC. Despite multimodal treatment approaches, the 3-year overall survival rate for stage III IBC remains low at approximately 74%, around 10% lower than the 83% for non-IBC.

Objectives: To evaluate whether the addition of neratinib, an irreversible pan-ErbB receptor small molecule tyrosine kinase inhibitor, improves the rate of pathological complete response in …


Does Performance Change Budgets? Punctuated Equilibrium, Performance, And The Budget For Juvenile Justice In An American State, Elaine Yi Lu, Robert Hines, Katherine Willoughby Jan 2025

Does Performance Change Budgets? Punctuated Equilibrium, Performance, And The Budget For Juvenile Justice In An American State, Elaine Yi Lu, Robert Hines, Katherine Willoughby

Publications and Research

How performance informs budgeting and budgets is contentious and unclear. Applying punctuated equilibrium theory, this research seeks to understand if performance information once placed on the media and macropolitical agendas can lead to long term budgetary shifts. This research highlights how the accumulation of performance information punctuated the funding scheme and created a new equilibrium over time.

This research uses mixed methods to study the impact of performance on Florida’s (USA) Department of Juvenile Justice (DJJ) over a 20-year period. First, we conduct a media review of 400 randomly sampled newspaper articles to characterize the media discourse around the DJJ …


Repressed Memories And The Body Keeps The Score: Public Perceptions And Prevalence, Kris-Ann S. Anderson, Quincy C. Miller, Deryn Strange, Kamala London Jan 2025

Repressed Memories And The Body Keeps The Score: Public Perceptions And Prevalence, Kris-Ann S. Anderson, Quincy C. Miller, Deryn Strange, Kamala London

Publications and Research

The “memory wars” resurgence has renewed debates over the validity of repressed memories. This revival appears linked to factors such as changing statutes of limitations, confusion about repression, and unchallenged social media content. In a nationally representative online survey of American adults (N = 1581), we examined (a) beliefs in repression and the body keeps the score, (b) the prevalence of recovered memory claims, and (c) the impact of question phrasing on recovered memory reporting. An overwhelming 94% of respondents expressed belief in repressed memory, and 77% endorsed the idea that the body keeps the score. Additionally, 3.6% (n = …


A Battle Of The Chatbots: An Exploratory Comparison Of Chatgpt, Gemini, Copilot, Claude, Perplexity And Huggingchat, Karen Okamoto Jan 2025

A Battle Of The Chatbots: An Exploratory Comparison Of Chatgpt, Gemini, Copilot, Claude, Perplexity And Huggingchat, Karen Okamoto

Publications and Research

This exploratory study compares the output of the free versions of six generative artificial intelligence (AI) chatbots—ChatGPT, Gemini, Copilot, Claude, Perplexity and HuggingChat. Five questions were submitted to all of the chatbots and examined according to the length of the response, tone of the response, and any additional features provided by the chatbots such as citations, web links, and helpful follow-up questions. This comparison found that Perplexity excelled at responding to all of the questions though others provided strong outputs as well, pointing to the possible importance of using multiple chatbot for answers and for continually examining different chatbots given …


The Towering Inferno: Art, Policy, And Legacy, Charles R. Jennings Jan 2025

The Towering Inferno: Art, Policy, And Legacy, Charles R. Jennings

Publications and Research

The Christian Regenhard Center for Emergency Response Studies, leveraging the expertise of its faculty, staff, Advisory Board and colleagues, has consistently programmed activities focused on high-rise fire safety. The upcoming 50th anniversary of the film The Towering Inferno was an inspiration.

We decided this would be more lighthearted and less purely technical than many of our events. We wanted to consider both the film, and use it to reflect on the state of fire safety in tall buildings in New York City.

Of course it does not escape us that the topic of fire safety is a serious one, …


Bronchoalveolar Lavage Cell Percentages As Diagnostic Markers Of Immune Checkpoint Inhibitor Pneumonitis, Mahnoor Mir, Felipe Soto, Pedro Antonio Amezcua Gomez, Rodrigo Del Rio Arroyo, Adarsh Suresh, Amber Su, Qiong Gan, John Stewart, Roberto Adachi, Diwakar D Balachandran, Lara Bashoura, Roberto F Casal, Burton F Dickey, George A Eapen, Scott E Evans, Horiana Grosu, Carlos A Jimenez, Julie Lin, David E Ost, Bruce F Sabath, Vickie R Shannon, Aung Naing, Jianjun Gao, Jia Wu, Karthik Suresh, Saadia A Faiz, Mehmet Altan, Ajay Sheshadri Jan 2025

Bronchoalveolar Lavage Cell Percentages As Diagnostic Markers Of Immune Checkpoint Inhibitor Pneumonitis, Mahnoor Mir, Felipe Soto, Pedro Antonio Amezcua Gomez, Rodrigo Del Rio Arroyo, Adarsh Suresh, Amber Su, Qiong Gan, John Stewart, Roberto Adachi, Diwakar D Balachandran, Lara Bashoura, Roberto F Casal, Burton F Dickey, George A Eapen, Scott E Evans, Horiana Grosu, Carlos A Jimenez, Julie Lin, David E Ost, Bruce F Sabath, Vickie R Shannon, Aung Naing, Jianjun Gao, Jia Wu, Karthik Suresh, Saadia A Faiz, Mehmet Altan, Ajay Sheshadri

Faculty, Staff and Student Publications

Introduction: Diagnostic biomarkers for immune checkpoint inhibitor pneumonitis (ICIP) are lacking. Bronchoalveolar lavage (BAL) lymphocytosis has been associated with ICIP, but studies have not evaluated BAL lymphocytosis as a diagnostic biomarker for ICIP.

Purpose: This study aimed to measure the association of BAL immune cell percentage with ICIP and test its performance as a diagnostic biomarker.

Methods: We performed a retrospective chart review of 476 patients treated with ICIs for solid organ or hematologic malignancies who underwent BAL between 2016 and 2022. Two independent reviewers, blinded to the results of BAL cell percentage, confirmed the diagnosis of ICIP or other …


Rapid Implementation Of Open-Access Pandemic Education For Global Frontline Healthcare Workers, Jacqueline Christianson, Erica Frank, Stacen Keating, Susan Boyer, Miriam Chickering Jan 2025

Rapid Implementation Of Open-Access Pandemic Education For Global Frontline Healthcare Workers, Jacqueline Christianson, Erica Frank, Stacen Keating, Susan Boyer, Miriam Chickering

College of Nursing Faculty Research and Publications

Background

The recent global pandemic posed extraordinary challenges for healthcare systems. Frontline healthcare workers required focused, immediate, practical, evidence-based instruction on optimal patient care modalities as knowledge evolved around disease management.

Objective

This course was designed to provide knowledge to protect healthcare workers; combat disease spread; and improve patient outcomes.

Methods

A team of global healthcare workers responded by rapidly creating a competency-based online course. To promote transcultural applicability, the course was developed by an international team of more than 45 educators from over 20 countries. Course delivery included a built-in language translation tool, routine updates, and several innovative course …


Partial Agonism In Heteromeric Gluk2/Gluk5 Kainate Receptor, Nabina Paudyal, Anindita Das, Elisa Carrillo, Vladimir Berka, Vasanthi Jayaraman Jan 2025

Partial Agonism In Heteromeric Gluk2/Gluk5 Kainate Receptor, Nabina Paudyal, Anindita Das, Elisa Carrillo, Vladimir Berka, Vasanthi Jayaraman

Faculty, Staff and Student Publications

Kainate receptors are a subtype of ionotropic glutamate receptors that form transmembrane channels upon binding glutamate. Here, we have investigated the mechanism of partial agonism in heteromeric GluK2/K5 receptors, where the GluK2 and GluK5 subunits have distinct agonist binding profiles. Using single-molecule Förster resonance energy transfer, we found that at the bi-lobed agonist-binding domain, the partial agonist AMPA-bound receptor occupied intermediate cleft closure conformational states at the GluK2 cleft, compared to the more open cleft conformations in apo form and more closed cleft conformations in the full agonist glutamate-bound form. In contrast, there is no significant difference in cleft closure …


Preliminary Validity Of A Daily Functional Status Pain Assessment Tool, Wally R. Smith, Rehan Qayyum, Alexandra Ulbing, Margaret S. Guy, Daniel M. Sop, Yue May Zhang Jan 2025

Preliminary Validity Of A Daily Functional Status Pain Assessment Tool, Wally R. Smith, Rehan Qayyum, Alexandra Ulbing, Margaret S. Guy, Daniel M. Sop, Yue May Zhang

Department of Medicine Faculty Publications

Objectives: Readiness for discharge for a sickle cell disease vaso-occlusive crisis is dictated by factors far beyond pain control, including physical function/activity. We therefore designed and tested a functional status-based pain assessment questionnaire in SCD patients hospitalized with vaso-occlusive crises.

Methods: Sickle cell disease patients on a preselected nursing unit rated 10 draft Functional status-Based Pain Assessment items of activities of daily living on a 5 point Likert scale (0-5) from “very easy” to “very difficult” daily on each day of their admission until discharge, at approximately the same time. Concurrently, they reported Numeric Rating Scale (0-10) pain intensity. …


Generating Real-World Evidence In Early Alzheimer's Disease: Considerations For Applying The Target Trial Emulation Framework To Study The Safety Of Anti-Amyloid Therapies, Xiaojuan Li, Sonal Singh, Bahareh Rasouli, Jennifer Lyons, Noelle M. Cocoros, Richard Platt, Ivan Abi-Elias, Jerry H. Gurwitz Jan 2025

Generating Real-World Evidence In Early Alzheimer's Disease: Considerations For Applying The Target Trial Emulation Framework To Study The Safety Of Anti-Amyloid Therapies, Xiaojuan Li, Sonal Singh, Bahareh Rasouli, Jennifer Lyons, Noelle M. Cocoros, Richard Platt, Ivan Abi-Elias, Jerry H. Gurwitz

Department of Medicine Faculty Publications

Anti-amyloid beta monoclonal antibodies (anti-Aβ mAbs) have received approval from the US Food and Drug Administration for the treatment of patients with mild cognitive impairment or mild dementia due to Alzheimer's disease (collectively known as early AD) based on evidence from clinical trials. However, whether findings from these trials are generalizable to the real world is uncertain. We need reliable evidence on the real-world safety of these treatments to inform decision making for clinicians, patients, and caregivers. Using lecanemab as an exemplar, we outline the key considerations in designing and implementing an observational study on safety and utilization outcomes using …


Cardiomyopathies Of Endocrine Origin: A State-Of-The-Art Review, Jenyfer M. Fuentes-Mendoza, Marcio J. Concepción-Zavaleta, Juan C. Morón-Siguas, Juan M. Muñoz-Moreno, Aranza I. Pérez-Reyes, Rodrigo Martinez-Galaviz, Raúl D. Aguilar-Castañeda, Oziel González-Godoy, Luis A. Concepción-Urteaga, José Paz-Ibarra Jan 2025

Cardiomyopathies Of Endocrine Origin: A State-Of-The-Art Review, Jenyfer M. Fuentes-Mendoza, Marcio J. Concepción-Zavaleta, Juan C. Morón-Siguas, Juan M. Muñoz-Moreno, Aranza I. Pérez-Reyes, Rodrigo Martinez-Galaviz, Raúl D. Aguilar-Castañeda, Oziel González-Godoy, Luis A. Concepción-Urteaga, José Paz-Ibarra

Department of Medicine Faculty Publications

Endocrine disorders are increasingly recognized as potentially reversible causes of secondary cardiomyopathies, yet they often remain underdiagnosed in clinical practice. These conditions-including thyroid dysfunction, acromegaly, pheochromocytoma, diabetes mellitus, adrenal disorders, among others-can significantly alter cardiac structure and function through hormonal excess, metabolic remodeling, and neurohumoral activation. Hyperthyroidism may lead to high-output heart failure (HF) and atrial fibrillation, while hypothyroidism is associated with diastolic dysfunction, pericardial effusion, and accelerated atherosclerosis. Acromegaly promotes biventricular hypertrophy and myocardial fibrosis via insulin-like growth factor 1 overproduction. Pheochromocytoma triggers catecholamine-induced cardiomyopathy, resembling Takotsubo syndrome and carrying a high risk of mortality if left untreated. Diabetes …


Politics In Public Health: Growing Partisan Divides In Covid-19 Vaccine Attitudes And Uptake Post-2021 Presidential Inauguration, Hongbin Fan, Zhongliang Zhou, Guanping Liu, Chi Shen, Qi Zhang Jan 2025

Politics In Public Health: Growing Partisan Divides In Covid-19 Vaccine Attitudes And Uptake Post-2021 Presidential Inauguration, Hongbin Fan, Zhongliang Zhou, Guanping Liu, Chi Shen, Qi Zhang

Epidemiology, Biostatistics, & Environmental Health Faculty Publications

Objectives: To investigate whether the 2021 U.S. presidential inauguration contributed to a widening of partisan divides in COVID-19 vaccine attitudes and uptake. Methods: We leverage the presidential inauguration as a natural experiment and analyze data from the Household Pulse Survey and CDC vaccination records. Using a difference-in-differences framework with continuous treatment, we examine how the transition differentially affected state-level vaccine refusal rates and county-level vaccination rates, based on varying levels of partisanship as measured by the Trump-Biden vote gap. Results: Following Biden's inauguration, vaccine refusal declined more in pro-Biden states. Distrust in government and vaccines accounted for approximately 80% of …


Mechanical Regulation Of Macrophage Metabolism By Allograft Inflammatory Factor 1 Leads To Adverse Remodeling After Cardiac Injury, Matthew Deberge, Kristofor Glinton, Connor Lantz, Zhi-Dong Ge, David P Sullivan, Swapna Patil, Bo Ryung Lee, Minori I Thorp, Adam Mullick, Steve Yeh, Shuling Han, Anja M Van Der Laan, Hans W M Niessen, Xunrong Luo, Nicholas E S Sibinga, Edward B Thorp Jan 2025

Mechanical Regulation Of Macrophage Metabolism By Allograft Inflammatory Factor 1 Leads To Adverse Remodeling After Cardiac Injury, Matthew Deberge, Kristofor Glinton, Connor Lantz, Zhi-Dong Ge, David P Sullivan, Swapna Patil, Bo Ryung Lee, Minori I Thorp, Adam Mullick, Steve Yeh, Shuling Han, Anja M Van Der Laan, Hans W M Niessen, Xunrong Luo, Nicholas E S Sibinga, Edward B Thorp

Faculty, Staff and Student Publications

Myocardial infarction (MI) mobilizes macrophages, the central protagonists of tissue repair in the infarcted heart. Although necessary for repair, macrophages also contribute to adverse remodeling and progression to heart failure. In this context, specific targeting of inflammatory macrophage activation may attenuate maladaptive responses and enhance cardiac repair. Allograft inflammatory factor 1 (AIF1) is a macrophage-specific protein expressed in a variety of inflammatory settings, but its function after MI is unknown. Here we identify a maladaptive role for macrophage AIF1 after MI in mice. Mechanistic studies show that AIF1 increases actin remodeling in macrophages to promote reactive oxygen species-dependent activation of …


Sentence Determination As A Function Of Sex Offender Gender, Kyle Gamache, Matt Zaitchik, Judith Platania, Willem Pontbriand Jan 2025

Sentence Determination As A Function Of Sex Offender Gender, Kyle Gamache, Matt Zaitchik, Judith Platania, Willem Pontbriand

Arts & Sciences Faculty Publications

The current study examines perceptions of dangerousness and sentencing recommendations for female sex offenders (FSOs) compared to male sex offenders (MSOs). Participants (N = 82) were randomly assigned to read one of three vignettes depicting a sexual offense committed by a male, female, or male-female co defendant pair. Key individual difference variables—Need for Cognition (NFC) and Gender Role Beliefs (GRB)—were assessed to examine their influence on sentencing and attributional judgments. NFC emerged as a significant moderator: participants with low NFC assigned longer sentences to FSOs, whereas high NFC participants gave longer sentences to MSOs. Participants endorsing traditional gender role beliefs …


Towards The Faa's Next Century: Clarifying Disclosure Requirements In Arbitration, Andrea K. Schneider, Brian Farkas Jan 2025

Towards The Faa's Next Century: Clarifying Disclosure Requirements In Arbitration, Andrea K. Schneider, Brian Farkas

Articles

This essay provides a roadmap to the current landscape of neutrality and disclosure. It then suggests three possible reforms to the FAA that would provide better guidance to arbitrators, parties, and courts. Moreover, this essay argues that if the FAA cannot be sufficiently amended, states should take the lead. States can continue to more clearly outline disclosure requirements and enforce clearer standards than the current version of the FAA.


Bismuth-Infused Perivascular Wrap Facilitates Delivery Of Mesenchymal Stem Cells And Attenuation Of Neointimal Hyperplasia In Rat Arteriovenous Fistulas, Allan John R Barcena, Joy Vanessa D Perez, Marvin R Bernardino, Jossana A Damasco, Erin Marie D San Valentin, Carleigh Klusman, Benjamin Martin, Gino Martin Canlas, Francisco M Heralde, Natalie Fowlkes, Richard R Bouchard, Jizhong Cheng, Steven Y Huang, Marites P Melancon Jan 2025

Bismuth-Infused Perivascular Wrap Facilitates Delivery Of Mesenchymal Stem Cells And Attenuation Of Neointimal Hyperplasia In Rat Arteriovenous Fistulas, Allan John R Barcena, Joy Vanessa D Perez, Marvin R Bernardino, Jossana A Damasco, Erin Marie D San Valentin, Carleigh Klusman, Benjamin Martin, Gino Martin Canlas, Francisco M Heralde, Natalie Fowlkes, Richard R Bouchard, Jizhong Cheng, Steven Y Huang, Marites P Melancon

Faculty, Staff and Student Publications

BACKGROUND: Mesenchymal stem cells (MSCs) have emerged as novel therapies for supporting arteriovenous fistula (AVF) maturation, and bioresorbable polymeric scaffolds have enabled sustained MSC delivery into maturing AVFs. However, the radiolucency of biopolymeric wraps prevents in vivo monitoring of their integrity and location, hindering long-term preclinical investigations.

METHODS: We infused bismuth nanoparticles (BiNPs) into polycaprolactone (PCL) to fabricate an electrospun perivascular wrap capable of MSC delivery and conducive to longitudinal monitoring using conventional imaging. We tested the wraps' effects on the attenuation of markers of neointimal hyperplasia (i.e., endothelial dysfunction, hypoxia, and inflammation), the leading cause of AVF failure, in …


Processing And Densification Of Multi-Phase High-Entropy Ceramics, Steven Smith Jan 2025

Processing And Densification Of Multi-Phase High-Entropy Ceramics, Steven Smith

Doctoral Dissertations

"This work focuses on the processing and densification of multiphase, high-entropy ceramics to promote their use in friction stir welding technologies. Several high-entropy systems including high-entropy borides, carbides, and their composites were produced. Boro/carbothermal and carbothermal synthesis were used to produce high-entropy powders from oxide powder mixtures. Composites of high-entropy borides and high-entropy carbides were produced using a sequential approach to produce both phases. The carbide was first produced using carbothermal reduction, then ZrH2 and B4C were added to the carbide powder to produce the high-entropy boride phase. The resulting powder was densified by spark plasma sintering and pressureless sintering, …


Drone-Based Multimodal Sensing On Vegetations And Data Analytics For Early Detection Of Gas Leakage From Underground Pipelines, Pengfei Ma Jan 2025

Drone-Based Multimodal Sensing On Vegetations And Data Analytics For Early Detection Of Gas Leakage From Underground Pipelines, Pengfei Ma

Doctoral Dissertations

"This study explored the feasibility of using multimodal remote sensors in the early detection of natural gas leaks from underground pipelines, as vegetation situated above pipelines can discern microbial changes in soil when affected by gas and exhibit physiological stress symptoms on leaves. Three sensors (RBG, thermal, and hyperspectral cameras) were utilized to monitor vegetation stress as an indicator of gas leaks. A laboratory experiment was conducted to evaluate the workability of vegetation for gas leak detection. Regular hyperspectral imagery was collected from test vegetations to identify gas stress and distinguish it from other environmental stressors such as salinity impact, …


Leveraging Deep Learning Models And Social Media Data For Enhanced Situation Awareness In Disaster Management, Ademola Abdulganiyu Adesokan Jan 2025

Leveraging Deep Learning Models And Social Media Data For Enhanced Situation Awareness In Disaster Management, Ademola Abdulganiyu Adesokan

Doctoral Dissertations

"In recent years, social media has become a crucial source of real-time data for disaster management, supporting emergency responses when traditional channels like 911 are overcrowded and overwhelmed. It offers authorities valuable data for developing effective strategies, especially when swift actions are essential to save lives. However, the informal language, ambiguous meanings, and irrelevant content on social media pose challenges to accurate classification and hinder the efficient extraction of disaster-relevant information, leading to inefficiencies in emergency response efforts.

This research focuses on seven key questions: i) How can we detect, classify, and analyze hate and offensive tweet emotions during large-scale …


Transport And Plugging Behavior Of Co2-Resistant Preformed Particle Gels In High Conductive Channels For Conformance Control, Adel Alotibi Jan 2025

Transport And Plugging Behavior Of Co2-Resistant Preformed Particle Gels In High Conductive Channels For Conformance Control, Adel Alotibi

Doctoral Dissertations

"Improving oil recovery is essential with rising global oil demand and declining production in mature fields. CO2 flooding has been widely applied as a major Enhanced Oil Recovery (EOR) method due to its effectiveness in boosting oil recovery while enabling safe carbon storage in the subsurface. However, in fractured and highly heterogeneous reservoirs, CO2 often flows through paths of least resistance, leading to early breakthrough or quick excessive CO2 production and leaving substantial oil in unswept zones or areas. Traditional in-situ polymer gels have been applied to control CO2 flooding conformance, their performance has been varied, …


Investigation Of The Transport And Plugging Behavior Of Preformed Particle Gels (Ppgs) In Fractures For Conformance Control In Carbonate Reservoirs, Abdulaziz A. Almakimi Jan 2025

Investigation Of The Transport And Plugging Behavior Of Preformed Particle Gels (Ppgs) In Fractures For Conformance Control In Carbonate Reservoirs, Abdulaziz A. Almakimi

Doctoral Dissertations

This study aims to systematically evaluate the performance of preformed particle gels (PPGs) in fractured carbonates mainly through a series of core flooding experiments. Carbonate reservoirs exhibit unique features of heterogeneity and pore geometry, while (PPGs) are known for their plugging efficiency, deformability, and dehydratable nature. The main goal of gel injection in fractured reservoirs is to place a gel pack appropriately into the fracture, diverting injected fluid to the oil-bearing matrix and reducing excessive water production. However, considerable dehydration of (PPGs) is possible at the adjacent matrix and within the fracture, which could lead to a filter-cake formation and/or …


A Comprehensive Analysis Of Climate Resilience Strategies For Small Island Developing States, Ashley-Ann Davis Jan 2025

A Comprehensive Analysis Of Climate Resilience Strategies For Small Island Developing States, Ashley-Ann Davis

Doctoral Dissertations

Small Island Developing States (SIDS) face unique and disproportionate challenges in their efforts to achieve climate resilience due to their geographic vulnerabilities, limited resources, and systemic economic and social constraints. This dissertation provides a comprehensive analysis of climate resilience strategies tailored to SIDS, addressing critical systemic issues and exploring interdisciplinary solutions. It synthesizes findings across four interconnected studies, including an analysis of disaster preparedness and response mechanisms in developing countries to identify gaps and opportunities for improving resilience in extreme events. The research investigates economic factors influencing energy portfolio transitions in the Caribbean, emphasizing the complexities of renewable energy adoption. …