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2025

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Market Reactions To Disruptions In The Aerospace Industry: An Event Study Analysis Of Abnormal Returns And Corporate Resilience, Rose L. Lauture Jan 2025

Market Reactions To Disruptions In The Aerospace Industry: An Event Study Analysis Of Abnormal Returns And Corporate Resilience, Rose L. Lauture

Doctoral Dissertations (DBA)

This study examines the effects of component failures, regulatory actions, and safety violations on stock returns and market volatility in the U.S. aerospace sector. Using FAA incident reports, WRDS market data, and corporate disclosures, the analysis combines event study methodology with ARCH/GARCH volatility models and a multiple regression approach. The results reveal that while incident frequency does not significantly affect stock prices measured by abnormal returns, firm-specific financial indicators—such as cash holdings and book-to-market ratio—play a substantial role. The study highlights the limited explanatory power of traditional regression models and calls for the inclusion of market risk and investor sentiment …


Evolution Of Bacteria: The Subsequent Relationships Between Different Species And Their Hosts, Helen Appleberry Jan 2025

Evolution Of Bacteria: The Subsequent Relationships Between Different Species And Their Hosts, Helen Appleberry

Dissertations

To explore the relationship between two recently identified bacterial species (S. anginosus and S. urinae), three aims were designed. First, niche ranges were identified via two metagenome databases. Different niche ranges were identified between the two groups. S. urinae was more specific to the urogenital tract. S. anginosus appeared to be present across human anatomical niches. Secondly, specific genes to the S. urinae group were identified. This gives insight into the genomic and phenotypic differences previously identified. Thirdly, a temporal study was created to view S. urinae in female urine over 8 weeks. This showed stability in the urinary microbiome …


Analyzing The Population Structure Of The Rhizobia Associated With Astragalus Lentiginosus, Joshua Adam Melnick Jan 2025

Analyzing The Population Structure Of The Rhizobia Associated With Astragalus Lentiginosus, Joshua Adam Melnick

Dissertations

Legumes are an incredibly diverse and agriculturally important family of plants. They have a special relationship with symbiotic bacteria known as rhizobia which fix nitrogen into ammonia within nodules on their roots. Astragalus is the largest plant genus on Earth, and the species Astragalus lentiginosus is extraordinarily diverse, consisting of approximately 40 varieties. However, the rhizobia of A. lentiginosus have never been studied. In this study, root nodules were extracted from 17 varieties of A. lentiginosus to obtain rhizobial strains and metagenomes. A. lentiginosus primarily associates with rhizobia from the genera Mesorhizobium and Allomesorhizobium. There was little evidence of horizontal …


Deciphering The Source Of Escherichia Coli In Urinary Tract Infections: A Comparative Metagenomic Analysis Of The Female Urogenital Microbiome, Alexis Annabel Avalos Jan 2025

Deciphering The Source Of Escherichia Coli In Urinary Tract Infections: A Comparative Metagenomic Analysis Of The Female Urogenital Microbiome, Alexis Annabel Avalos

Dissertations

In 2019, there was a 140.19% increase in deaths due to urinary tract infections (UTIs) compared to 1990, worldwide. One of the common uropathogens known to associate with UTIs in females is Escherichia coli. The prevailing belief is that E. coli in the bladder originates in the rectum, passing its way from the perineal, to the vagina, and finally into the bladder. Known as the Fecal-Perineal-Urethral (FPU) hypothesis, this “origin story” has been supported by several studies that have relied on genotyping or serotyping isolates collected from the bladder and rectum. Most notably, culturing isolates from samples has been central …


Reconceptualizing Christian Nationalism, Robert Stevenson Jan 2025

Reconceptualizing Christian Nationalism, Robert Stevenson

Dissertations

This thesis sets out to critically engage with existing research on Christian nationalism. It argues that current research suffers from a methodological focus that is too broad, and theoretical grounding that is too imprecise, both of which prevent researchers from grasping the full scope and intent of Christian nationalism, as imagined by Christian nationalists themselves. Drawing on data collected from X accounts (formerly Twitter) of Christian nationalist users, Christian nationalist podcasts, and Christian nationalist books, it employs qualitative content analysis, mapped to Bourdieusian field theory to provide a structured approach for the understanding complex data involving multiple spheres of power, …


Role Of Coronavirus Envelope Protein On Infectivity, Garrett E. Zaagman Jan 2025

Role Of Coronavirus Envelope Protein On Infectivity, Garrett E. Zaagman

Dissertations

Coronaviruses infect a wide range of hosts and have caused recent human pandemics. While much has been learned, gaps remain in understanding viral assembly and egress, particularly the role of the envelope (E) protein in specific infectivity. To study this, recombinant MHV viruses were created with E gene deletions and HiBiT-tagged spike (S) proteins to monitor virion release. In mouse cells, MHV∆E S-HiBiT secreted less spike and fewer infectious particles, indicating reduced specific infectivity. Comparisons between human HeLa-CEACAM and mouse DBT cells showed species-specific support for virus production. TMED10, a host membrane protein, was tested as a potential E-interacting partner …


Anti-Inflamatory Mechansim Of Bacillus Subtilis Derirved Exopolysaccharide, Adrian Taylor Ibarra Jan 2025

Anti-Inflamatory Mechansim Of Bacillus Subtilis Derirved Exopolysaccharide, Adrian Taylor Ibarra

Dissertations

Exopolysaccharides (EPS) secreted by the commensal bacterium Bacillus subtilis exhibit potent anti-inflammatory properties, yet the underlying molecular mechanisms remain incompletely understood. We hypothesized that EPS reprograms antigen-presenting cells toward a tolerogenic state by modulating TLR4–MyD88 signaling. To test this, we began using a chemically defined, high-yield EPS production and purification protocol that largely eliminates protein and DNA contaminants, thus improving functional reproducibility across experiments using this new method. In vitro, EPS engaged TLR4 on murine dendritic cells (DC2.4) without inducing classical NF-κB activation, seen by LPS stimulation. Rather, EPS treatment upregulated inhibitory molecules, PD-L1 and PD-L2 while leaving activation markers, …


Investigating The Mechanism Of Resistance To Ido1 Enzyme Inhibitor Treatment In Human Glioblastoma, Kyla Shivakumar Hatton Jan 2025

Investigating The Mechanism Of Resistance To Ido1 Enzyme Inhibitor Treatment In Human Glioblastoma, Kyla Shivakumar Hatton

Dissertations

Glioblastoma (GBM) is the most common and most aggressive form of adult cancer in the central nervous system, with GBM accounting for the majority of all malignant brain tumors. GBM is currently considered to be an incurable form of cancer, with over 14,000 patients diagnosed in the United States last year. Given the success of immunotherapy for treating other types of cancer, our group has investigated the possibility of therapeutically neutralizing immunosuppressive indoleamine 2,3 dioxygenase 1 (IDO1) in patients with GBM. Canonically, IDO1 is an immunosuppressive cytoplasmic enzyme that catalyzes the first step in metabolizing L-tryptophan into L-kynurenine (ie. ↓L-Trp→↑L-Kyn). …


Developing Chemically Defined Serum-Free Medium For Leukemic Blast And Stem Cell Expansion, Carmen Eva Finley Jan 2025

Developing Chemically Defined Serum-Free Medium For Leukemic Blast And Stem Cell Expansion, Carmen Eva Finley

Dissertations

The relapse and chemotherapy resistance are the major challenges of acute myeloid leukemia (AML) treatment, driven by a rare population of leukemia stem cells (LSCs). LSCs are unique types of cells which evade standard chemotherapies and can regenerate AML post-treatment. Targeting LSC therapy remains limited, in part due to the lack of reliable in vitro AML culture systems to grow LSCs for drug discovery. This study aimed to engineer a chemically defined, serum-free 2D in vitro culture condition that supports either the expansion of leukemic blasts (LBs) or primary human LSCs by optimizing current protocols for hematopoietic stem cells (HSCs) …


Investigating Whether Txnrd2 Is A Therapeutic Target Against Triple Negative Breast Cancer Using African American-Derived Models, Keacha Chang Jan 2025

Investigating Whether Txnrd2 Is A Therapeutic Target Against Triple Negative Breast Cancer Using African American-Derived Models, Keacha Chang

Dissertations

Despite similar breast cancer incidence rates, African American (AA) women experience a 40% higher mortality rate compared to Caucasian American (CA) women. This disparity is multifactorial and particularly pronounced in the Chicago area. AA women are twice as likely to be diagnosed with triple-negative breast cancer (TNBC), often at a younger age and with more aggressive disease. TNBC is a heterogeneous subtype lacking targeted therapies and is associated with the poorest prognosis among breast cancer types. Therefore, there is an urgent need for novel therapeutic strategies for TNBC, especially those tailored to AA patients. The thioredoxin pathway is essential for …


Examining Secretory Pathways In Inflammasome Activated Innate Immune Cells, Alejandra Castellanos Urquidez Jan 2025

Examining Secretory Pathways In Inflammasome Activated Innate Immune Cells, Alejandra Castellanos Urquidez

Dissertations

Innate immune cells serve as the first line of defense by detecting pathogens through pathogen- and damage-associated molecular patterns (PAMPs and DAMPs). Recognition of PAMPs triggers the synthesis and secretion of pro-inflammatory proteins, with the inflammasome playing a key role in the secretion of interleukin-1β (IL-1β), a crucial part of the innate immune response. Upon inflammasome activation, the release of signal-peptide lacking cytoplasmic proteins such as IL-1β occurs through non-classical pathways known as unconventional protein secretion (UCPS), which vary depending on the cell type and stimulus which helps tailor the extent of pro-inflammatory protein secretion. Broadly, UCPS cargoes are released …


"I'M Not Having Fun Anymore": A Qualitative Analysis Of Gender And Harassment In Bars And Clubs, Phoebe Marie Jackson Jan 2025

"I'M Not Having Fun Anymore": A Qualitative Analysis Of Gender And Harassment In Bars And Clubs, Phoebe Marie Jackson

Dissertations

Sexual harassment, while often spoken about in hushed tones or ignored altogether, happens frequently and often loudly. 66 percent of women who have experienced sexual harassment report that the harassment took place in a public space, such as work, school, or on the street (Kearl, 2018). Harassment is not discreet, but rather normalized, and those who experience it are expected to brush it off or take it in their stride. However, such harassment and subsequent dehumanization has a deteriorating effect on the mental well-being of those affected (Graham et. al., 2016). This study aims to hone in on the effect …


Editor's Note, Marites Tiongco Jan 2025

Editor's Note, Marites Tiongco

DLSU Business & Economics Review

No abstract provided.


Urban Coyotes As A Source Of Conflict With Humans: An Evaluation Of Common Management Practices, Paul D. Curtis, David L. Bergman, Angeline Barker, Daniel Bogan, Mary Ann Bonnell, Pierre Canac-Marquis, David Drake, Dave Kay, Brian F. Wakeling, H. Bryant White Jan 2025

Urban Coyotes As A Source Of Conflict With Humans: An Evaluation Of Common Management Practices, Paul D. Curtis, David L. Bergman, Angeline Barker, Daniel Bogan, Mary Ann Bonnell, Pierre Canac-Marquis, David Drake, Dave Kay, Brian F. Wakeling, H. Bryant White

Human–Wildlife Interactions Monographs

Wildlife often serves as a catalyst for conflict among stakeholders. Management actions that are intended to address sources of disagreement may initiate additional conflict. The Association of Fish and Wildlife Agencies Human–Wildlife Conflict Working Group initiated an effort to identify management actions commonly used to address unwanted coyote (Canis latrans) interactions within urban environments and identify the benefits and challenges associated with each action. Challenges with coyotes in urban environments include aggressive behavior toward humans and pets, attacks, disease exposure, and domestic livestock damage. Although elimination of all attractants would prove preventative in most instances, in practice this …


Pre-Migration Victimization And Fear Of Violent Crime Among New Arrivals In Chicago / Victimización Y Miedo Al Crimen Violento En El País De Origen De Los Migrantes Recién Llegados A Chicago, Cristian L. Paredes, Keyla Navarrete, Anna E. Bullock, Brianna Hernandez, Raymond A. Akumbilim Jan 2025

Pre-Migration Victimization And Fear Of Violent Crime Among New Arrivals In Chicago / Victimización Y Miedo Al Crimen Violento En El País De Origen De Los Migrantes Recién Llegados A Chicago, Cristian L. Paredes, Keyla Navarrete, Anna E. Bullock, Brianna Hernandez, Raymond A. Akumbilim

Sociology: Faculty Publications and Other Works

This project explores the situations and experiences of new arrivals/asylum seekers who have recently arrived in Chicago. Chicago has experienced a significant increase in the number of newcomers, due to Operation Lone Star, launched by Texas Governor Greg Abbott in March 2021. Since August 2022, Governor Abbott has bused more than 30,000 migrants to Chicago. The City of Chicago has acknowledged its responsibility to welcome everyone regardless of immigration status, adopting a proactive stance toward this humanitarian emergency. However, newcomers still struggle to get access to basic needs in the city. We have conducted a face-to-face, cross-sectional survey to collect …


Accessing Online And Remote Learning Platforms In Kenyan Remote Areas During Covid-19 Pandemic, Florence Deya, Jane Rarieya Jan 2025

Accessing Online And Remote Learning Platforms In Kenyan Remote Areas During Covid-19 Pandemic, Florence Deya, Jane Rarieya

Institute for Educational Development, East Africa

Online learning has taken root and with the advancement in technology more and more educators are embracing online learning. During the COVID-19 pandemic, with total shut down of face-to-face learning, the Kenyan government had moved learning online and remotely. To find out on how learners in remote areas were experiencing learning during the COVID-19 pandemic, a study was carried out using rapid ethnography design. Five final year secondary students were sampled. Data was collected through interviews, observations, and document analysis. This paper reports on the findings of online and remote learning platforms, which were available, accessed, and preferred by the …


Bibliometric Analysis With R Biblioshiny On Safety Behavior In Aviation, Büşra Yıldırım, İnan Eryılmaz, Ahmet Karacan, Nusret Erceylan Jan 2025

Bibliometric Analysis With R Biblioshiny On Safety Behavior In Aviation, Büşra Yıldırım, İnan Eryılmaz, Ahmet Karacan, Nusret Erceylan

International Journal of Aviation, Aeronautics, and Aerospace

Safety behaviors in aviation are not limited to technical knowledge and skills in ensuring the safety of flight operations, but also include the attitudes, decision-making processes and collaborations of individuals and teams. In this context, in this study, a bibliometric analysis of publication and citation trends, key concepts and interactions of studies in the field was conducted to identify current and potential trends in aviation and safety behavior-based research, and to explore the intersections between safety behavior and aviation studies and the areas waiting to be explored. The bibliometric analysis using the RStudio-based Biblioshiny program was conducted on 1065 articles …


Evaluating The Reporting And Safety Culture Of An Airline According To Patankar And Sabin's Safety Culture Pyramid, Seda Mumlu Karanfil Jan 2025

Evaluating The Reporting And Safety Culture Of An Airline According To Patankar And Sabin's Safety Culture Pyramid, Seda Mumlu Karanfil

International Journal of Aviation, Aeronautics, and Aerospace

As a result of the literature review, it is seen that the safety management system in airline businesses is mostly evaluated with Reason's just culture model. The fact that there is no research examining Patankar and Sabin's (2010) safety culture pyramid on airline operations, except for a study conducted in the field of ground handling services (Poçar, Işık, & Durmaz, 2022), constitutes the importance and unique value of the research. As stated by Poçar et al. (2022), Patankar and Sabin's (2010) safety culture pyramid is not sufficiently included in practice, and this model is important in terms of drawing attention …


Feminist Medievalisms: Embodiment And Vulnerability In Literature And Film, By Usha Vishnuvajjala, Lucy Barnhouse Jan 2025

Feminist Medievalisms: Embodiment And Vulnerability In Literature And Film, By Usha Vishnuvajjala, Lucy Barnhouse

Medieval Feminist Forum: A Journal of Gender and Sexuality

No abstract provided.


Natural Allies: A Qualitative Exploration Of The Impact Of Nature Immersion For Wellbeing And Its Relevance To Nursing: Challenges And Opportunities On The Journey Towards Interconnected Human And Planetary Health, Sarah Howes Jan 2025

Natural Allies: A Qualitative Exploration Of The Impact Of Nature Immersion For Wellbeing And Its Relevance To Nursing: Challenges And Opportunities On The Journey Towards Interconnected Human And Planetary Health, Sarah Howes

School of Nursing and Midwifery Theses

Human beings have evolved in direct relationship with the natural world, our health and survival inextricably connected to that of the planet. In recent years, an expanding evidence base has extolled the benefits of time in green and blue space for restoration from busy and stressful lives, yet limited literature explores the impact of time in nature from a nursing perspective. Through three study phases, this reflexive qualitative ethnographic study examines the complex, multifaceted and perpetually shifting contexts which influence nature connection and sustainability concepts in nursing, highlighting a shared vulnerability between people and planet. Through a critical interpretive synthesis …


Lipid Biomarkers For Marine Fungi, Emily Cooper Jan 2025

Lipid Biomarkers For Marine Fungi, Emily Cooper

School of Geography, Earth and Environmental Sciences Theses

Marine fungi play key roles as parasites and saprotrophs in marine ecosystems and are important degraders of organic matter. They likely facilitate the remineralisation of marine carbon, thus have a profound impact on marine biogeochemical cycles. However, as little is known about their global abundance and biomass, fungi are yet to be included in biogeochemical models. Lipid biomarkers can be used to assess microbial abundance and biomass due to their specificity and may be utilised to explore the viability and trophic dynamics of marine microbial communities. Although lipid biomarkers for fungi have been used in terrestrial environments, such as soils, …


Dred Scott, Military Enslavement, And The Case For Reparations, Hugh Barrett Mcclean Jan 2025

Dred Scott, Military Enslavement, And The Case For Reparations, Hugh Barrett Mcclean

All Faculty Scholarship

For more than a decade, Dred Scott was enslaved by a U.S. Army officer in a military system that perpetuated the institution of slavery in the free states and Northern territories of the antebellum period. Scott’s life, his lawsuit for freedom, and the U.S. Supreme Court case holding that Black people have “no rights which the white man was bound to respect” became infamous. But the history of the Dred Scott case and the military’s use of enslaved persons is largely unknown. Drawing on reparations advocacy in the Rosewood and Tulsa race massacre cases and other historical precedent for reparations, …


Unh/Noaa Joint Hydrographic Center 2025 Performance And Progress Report Executive Summary, Larry A. Mayer Jan 2025

Unh/Noaa Joint Hydrographic Center 2025 Performance And Progress Report Executive Summary, Larry A. Mayer

Center for Coastal and Ocean Mapping

No abstract provided.


Unh/Noaa Joint Hydrographic Center 2025 Performance And Progress Report Executive Summary, Larry A. Mayer Jan 2025

Unh/Noaa Joint Hydrographic Center 2025 Performance And Progress Report Executive Summary, Larry A. Mayer

Center for Coastal and Ocean Mapping

Reporting Period: 01/01/2025–12/31/2025


The Ethical Dilemma Of Social Media, Janet H. Southerland Jan 2025

The Ethical Dilemma Of Social Media, Janet H. Southerland

Journal of the American College of Dentists

Technology and digital communication have radically altered how we communicate and interact. As a consequence, the ethical use and application of technology within the profession, particularly the utilization of social media, is essential to preserving and upholding the tenets of professional conduct across dentistry.


J Am Coll Dent 2025 91 4 Jan 2025

J Am Coll Dent 2025 91 4

Journal of the American College of Dentists

The Journal of the American College of Dentists (JACD) publishes scholarly articles, editorials, essays, and reflections addressing the ethical, professional, and social dimensions of dentistry. The Journal serves as a forum for advancing ethics, professionalism, leadership, and excellence within the dental community. By fostering dialogue across disciplines and perspectives, JACD provides readers with insights that encourage ethical, professional practice, lifelong learning, and service to the public, reinforcing dentistry’s commitment to advancing oral healthcare and the common good.


Breaking Down The Silos: Dentistry’S Ethical Responsibility As A Partner In Healthcare, Toni M. Roucka Rn, Dds, Ma, Facd, Scott Tomar Dmd, Drph, Facd Jan 2025

Breaking Down The Silos: Dentistry’S Ethical Responsibility As A Partner In Healthcare, Toni M. Roucka Rn, Dds, Ma, Facd, Scott Tomar Dmd, Drph, Facd

Journal of the American College of Dentists

The Ethics Summit, Breaking Down the Silos: Dentistry’s Ethical Responsibility as a Partner in Healthcare, was held on September 12-13, 2024, in Rockville, Maryland. Sponsored by the American College of Dentists Foundation (ACDF) and the Santa Fe Group (SFG), this issue of the JACD is dedicated to the proceedings of that important event.


“Digital Shame Shift”: From Telling The Pain To Recording The Truth — Black Maternal Health And Digital Counter-Narrative Storytelling On Tiktok, Odera Covenant Ezenna Jan 2025

“Digital Shame Shift”: From Telling The Pain To Recording The Truth — Black Maternal Health And Digital Counter-Narrative Storytelling On Tiktok, Odera Covenant Ezenna

Theses and Dissertations

This dissertation explores how digital storytelling on TikTok is used to challenge medical racism, with a particular focus on Black maternal health. Guided by Critical Race Theory (CRT) and Critical Technocultural Discourse Analysis (CTDA), the study examines how TikTok users—ranging from Black mothers to healthcare professionals—create and circulate counter-narratives through two prominent campaigns: #BlackMaternalHealthWeek and #BlackMamasMatter. These digital stories serve as acts of resistance, disrupting dominant medical discourse and amplifying the lived experiences of Black birthing individuals. The research analyzes over 2900 TikTok videos posted between 2021 and 2024, identifying key themes, storytelling strategies, and rhetorical shifts over time. The …


Visual Thinking Informed By Repetition: A Practice-Based Methodology, Julia Heurling Jan 2025

Visual Thinking Informed By Repetition: A Practice-Based Methodology, Julia Heurling

School of Art, Design and Architecture Theses

This artistic research proceeds from the idea that visual thinking is thinking about images through images. It explores how ideas are instigated, developed, and articulated exclusively through visual elements from a practice-based perspective. The use of repetition as a method of thinking is rooted in my previous practice as a pattern designer. I consider this a cognitive process based on the assumption that repetition is a tool for abstraction, as it changes one’s perspective from the particular to the general. Abstraction, in this context, becomes a method for processing information (i.e. to think visually).My artistic practice is engaged in combining …


Opening Spaces For The Emergence Of Community Economy Initiatives, Timothy Crabtree Jan 2025

Opening Spaces For The Emergence Of Community Economy Initiatives, Timothy Crabtree

School of Art, Design and Architecture Theses

The background to the thesis is the crisis of affordable housing in the UK, and the emergence of community housing initiatives as a response. There are enabling organisations which provide support, but despite an increasing recognition of the contribution that housing makes to carbon emissions, affordability rather than sustainability remains the primary focus. In particular, the use of natural materials with low embodied carbon is often dismissed as unaffordable. The thesis therefore explores how a community housing enabling organisation might reconcile the apparently conflicting aims of affordability and sustainability. There is a gap in research into this area, in particular …