Digital Commons Network^™

Fructose Induces Metabolic Changes Distinctly Different From Glucose In A N2a Cell Line., Catherine A. Ghigleri

All Master's Theses

Over the last 50 years, there has been a rise in diagnoses of Alzheimer’s Disease and other dementias associated with metabolic stress. This parallels an increase in fructose consumption and has led to research on the effects of fructose on the hippocampus, a brain structure responsible for learning and long-term memory formation. The hippocampus is also a region of the brain that metabolizes fructose. Experiments using animals fed diets containing fructose have shown a correlation between fructose consumption, learning impairment, and structural changes to the hippocampus in animals’ brains. However, the effects of fructose on hippocampal neurons have not been …

Evaluating Geoai-Generated Data For Maintaining Vgi Maps, Lasith Niroshan, James D. Carswell

Research Outputs: 2025-Present

Geospatial Artificial Intelligence (GeoAI) offers a scalable solution for automating the generation and updating of volunteered geographic information (VGI) maps—addressing the limitations of manual contributions to crowd-source mapping platforms such as OpenStreetMap (OSM). This study evaluates the accuracy of GeoAI-generated buildings specifically, using two Generative Adversarial Network (GAN) models. These are OSM-GAN—trained on OSM vector data and Google Earth imagery—and OSi-GAN—trained on authoritative “ground truth” Ordnance Survey Ireland (OSi) vector data and aerial orthophotos. Altogether, we assess map feature completeness, shape accuracy, and positional accuracy and conduct qualitative visual evaluations using live OSM database features and OSi map data as …

Los Estudios Latinoamericanos Ante El Renacimiento Psicodélico, Alberto Ribas-Casasayas

Modern Languages & Literature

The chapter analyzes erasures and appropriations that the discourse of the psychedelic renaissance arising in the Global North imposes on long-standing practices in indigenous societies and countercultural environments. It also suggests ways in which a critical Humanities can, from a Latin American perspective, offer more inclusive understandings of the psychedelic experience.

Are We Safe In The Digital World? Why We Still Fall Victim To Cybercrime, Kevin Le

Honors Papers and Posters

Cybersecurity has only recently gained press coverage as millions of individuals are victimized by cyberattacks. While current cybersecurity measures offer some protection, human error has been the number one cause of cyberattacks for the past eight years (Verizon, 2024). Cybercrime continues to evolve in complexity, leveraging advanced technology and human psychology to bypass traditional security systems. This study examines why individuals still fall victim to cyberattacks. It explores the psychological and cognitive factors that make individuals vulnerable, focusing on social engineering techniques such as phishing and pretexting. This study also analyzes factors from psychological theories, including Protection Motivation Theory, Routine …

Archeota, Fall/Winter 2024, Sarah Miller, Kaitlyn O'Dell, Erica Leff, Peyton Walters, Joshua Insel

Archeota

Archeota is a platform for SJSU iSchool students to contribute to the archival conversation. It is written BY students, FOR students. It provides substantive content on archival concerns and issues and promotes professional development in the field of archival studies. Archeota upholds the core values of the archival profession.

Contents

A Tale of Two Film Archives: History and Impact of the British Film Institute and the Cinémathèque Française by Sarah Miller

Enhancing Archival Access with Sustainability: Insights from a Library Scholar Internship at Cal Poly Humboldt by Kaitlyn R. O’Dell

Farewell to Our Winter 2024 Graduate: Interviews with SAA Student …

A Fear Of Ideas? Social Media, Foreign Influence, And National Security In A New Era Of Great-Power Competition, Michael Park

Fordham Intellectual Property, Media and Entertainment Law Journal

The recent spate of legal restrictions on the use of TikTok and other foreign-controlled social media applications highlight concerns over personal data collection, but also how fears over the potential foreign influence of ideas from adversarial foreign governments—whether by propaganda, censorship, or disinformation—have re-emerged in the national security debate. Yet there are concerns that this new era of great power competition will be the basis for justifying overreaching speech regulations that hinder access to information and ideas under the aegis of national security. This work attempts to examine the recent enactment of speech restrictions or bans on foreign-controlled applications within …

Reevaluating Force Majeure Clauses In The Aftermath Of The Covid-19 Pandemic And Its Implications On The Entertainment Industry, Esther Animalu

Fordham Intellectual Property, Media and Entertainment Law Journal

No abstract provided.

Protecting What's Yours: Rights, Risks, And Realities In Ip And Entertainment, Fordham Iplj

Fordham Intellectual Property, Media and Entertainment Law Journal

No abstract provided.

The Ozempic Paradox: How Much Is Too Much In The Race For Weight Loss And Diabetes Treatment?, Jack Bekos

Fordham Intellectual Property, Media and Entertainment Law Journal

No abstract provided.

The Right To (Digital) Identity, Sarah M. Snow

Fordham Intellectual Property, Media and Entertainment Law Journal

Identity verification is a prerequisite for full participation in modern society. Access to financial services, employment, housing, healthcare, education, and civic engagement all hinge on an individual’s ability to prove their identity. Millions of Americans—particularly marginalized groups—struggle with the rigid, bureaucratic, and often discriminatory processes of traditional identity verification systems. Without legally recognized identification, individuals are effectively excluded from economic and civic life. This Note argues that the ability to prove one’s identity is a protected interest. It proposes adoption of a federal Self-Sovereign Identity (SSI) as a legal and technological mechanism to guarantee all Americans have access to a …

Legal Practice 2.0: Emerging Technology And The Law, John Haried

Western New England Law Review

This article examines the legal profession's transition into "Legal Practice 2.0," where lawyers maintain the same fundamental goals and requirements but conduct business through emerging technologies that affect every aspect of legal practice. This piece was written by Attorney John Haried specifically for publication following his presentation at the 2024 Western New England Law Review Symposium.

2025-2026 Graduate Catalog And Course Descriptions, Rochester Institute Of Technology

Graduate Catalog and Course Descriptions

No abstract provided.

2025-2026 Undergraduate Catalog And Course Descriptions, Rochester Institute Of Technology

Undergraduate Catalog and Course Descriptions

No abstract provided.

Development Of Nanoemulsion Formulation Incorporating Copaiba Oleoresin And Cidofovir To Enhance Skin Permeability In Topical Application For Hpv-Related Skin Conditions, Mansi Dilip More

Master’s Theses - College of Pharmacy and Health Sciences

The objective of this study was to develop a 1% cidofovir-loaded copaiba oleoresin nanoemulsion and evaluate its potential to enhance topical drug permeability for the treatment of Human Papillomavirus (HPV)-associated skin conditions. The formulation combined the antiviral properties of cidofovir with the anti-inflammatory and antimicrobial characteristics of copaiba oil to improve drug delivery and therapeutic efficacy.

Nanoemulsions were prepared using a probe sonication method. Seven formulations (F1–F7) with varying compositions were initially evaluated for particle size, polydispersity index (PDI), stability, and transparency. Among these, formulation F7 exhibited a mean particle size of 56.1 ± 3.12 nm, a PDI of 0.126 …

Equipped To Manage Risk, Case Western Reserve University School Of Law, Law-Medicine Center

Case Law-Med

• Message from the co-directors
• Newsflash
• Research roundup
• Faculty briefs
• Legal insights
• Awards & accolades
• Joining the team
• Enhancing access
• Equipped to manage risk
• Noteworthy
• Experiential education
• Preparing to practice

In Brief, Case Western Reserve University School Of Law

In Brief

Table of Contents

• Message from the Dean
• Specialty Programs Ranked Among the Best
• AI Certification Requirement
• Curricular Enhancements
• New Faculty Members
• Scholarly Impact
• Conferences and Lectures
• A New Era for Business Law at CWRU
• Meet the New Class
• News from the Kramer Law Clinic
• Impactful Student Initiatives
• Mock Trial and Moot Court Success
• Alumni Spotlight
• Society of Benchers
• Alumni Committees
• Class Notes
• In Memoriam
• Honor Roll of Donors

Optimization And Efficacy Of Car T Cells Derived From Newly Generated Anti-Cd22 Monoclonal Antibody For Blood Cancer Treatment, Wipawadee Ruengdej

Chulalongkorn University Theses and Dissertations (Chula ETD)

Chimeric antigen receptor (CAR) T-cell therapy has revolutionized the treatment of B-cell malignancies. Nevertheless, relapse due to loss of CD19 expression remains a major clinical challenge. CD22 serves as an alternative target because of its consistent expression on malignant B cells, even in CD19-negative disease. Optimization of CD22-directed CAR design is therefore critical to enhance antitumor potency and persistence. Two novel anti-CD22 CAR constructs were generated from monoclonal antibody clones 24A7G6 and 29H9C8, each incorporating either a 4-1BB or CD28 costimulatory domain. The resulting CAR T cells were evaluated for proliferation, phenotype, and cytotoxicity against CD22-positive (Raji, Nalm-6) and CD22-negative …

Understanding Math Proficiency Gaps, Mia Cha Bustamante

Education Masters Theses

As a sixth-grade teacher at a suburban elementary school in the Pacific Northwest, I observed that many students entered my classroom with significant gaps in foundational math skills. In Fall 2025, my classroom-based assessments revealed that a majority of my students were performing below grade level, particularly in numbers and operations in base ten- place value in decimals, multi-digit calculations and operations, and algebraic thinking- translating words to expressions, finding patterns, and solving multi-step problems. The purpose of this research is to investigate the question: How do student-reported experiences with foundational skill gaps, COVID-19 disruptions, and emotional factors help explain …

A Woman’S World Through The Lens Of Socialized Politics: How Accurate Knowledge Politically And Socially Empowers A Woman’S Autonomy, Claire G. Herzog

Undergraduate Honors Theses

Women have dealt with being perceived as inferior to men, defective, and in need of control. My research draws a connection between the ways societal beliefs, judicial action and political action interact with each other to reinforce and reproduce these limiting beliefs about women. The interaction between these institutions result in underlying policies that target women's rights, silencing their voices and sense of independence, all while aiming to control the female body completely. Despite the perception that modern society has moved away from the sexist beliefs that had been created and ingrained into society centuries ago, we are left with …

The Role Of Advocacy And Occupational Justice In Increasing The Accessibility Of Parks For Parents With Disabilities, Nathan Burke-Tan

Doctoral Projects

The purpose of this doctoral capstone project was to address ongoing accessibility barriers experienced by adults with disabilities, particularly those in caregiving roles, in public parks and playgrounds in the greater San Diego region. Although many parks meet the minimum requirements of the Americans with Disabilities Act (1990), research shows that caregivers with disabilities continue to encounter obstacles that limit safe, meaningful participation in community spaces (Dalpra, 2022; Fernelius, 2017; Firkin et al., 2024; Movahed et al., 2023; Ogletree et al., 2020; Prellwitz & Skar, 2007). These persistent gaps indicate a need for stronger advocacy and clearer public awareness of …

Identification Of Potential Prophylactic Medical Countermeasures Against Acute Radiation Syndrome (Ars), Kia T. Liermann-Wooldrik, Arpita Chatterjee, Elizabeth A. Kosmacek, Molly Myers, Oluwaseun Adebisi, Louise Monga-Wells, Liu Mei, Michelle P. Takacs, Patrick H. Dussault, Daniel R. Draney, Robert Powers, James W. Checco, Chittibabu Guda, Tomáš Helikar, David B. Berkowitz, Kenneth W. Bayles, Alan H. Epstein, Lynnette Cary, Daryl J. Murry, Rebecca E. Oberley-Deegan

Journal Articles: Pathology and Microbiology

Acute radiation syndrome (ARS) occurs when hematopoietic or gastrointestinal cells are damaged by radiation exposure causing DNA damage to the bone marrow and gastrointestinal epithelial stem cell populations. In these highly proliferative cell types, DNA damage inhibits stem cell repopulation. In humans and animals, this inability to regenerate stem cells is lethal. Within this manuscript, several compounds, Amifostine, Captopril, Ciprofloxacin, PrC-210, 5-AED (5-androstene-3β,17β-diol), and 5-AET (5-androstene-3β,7β,17B-triol), are assessed for their ability to protect against ARS in an in vitro and/or in vivo setting. ARS was accomplished by irradiating mouse bone marrow cells or rat intestinal epithelial (IEC-6) cells in vitro …

The Rescue Of Wahutedew’Á And The Epistemological Reforestation: An Analysis Of Time In A Terra Dos Mil Povos, By Kaká Werá Jecupé, Ivo Cruz

The Coastal Review

It is estimated that in 1500, the year the Portuguese arrived in America, there was a population of 2,431,000 inhabitants, according to historian John Hemming (1978), who occupied the lands that we now know as Brazil. These peoples had their own culture whose cosmology was destroyed and erased over time by a violent process of colonization. Even though entire groups were decimated, much of their influence is still alive in Brazilian culture. This influence can be found in vocabulary, cuisine, and even religious practices. With the aim of rescuing ancestral narratives and knowledge of various native peoples, Kaká Werá Jecupé …

Light And Darkness For Aesthetic Pleasure: An Exploration Of J.M.G. Le Clézio’S Early Writings And Jun’Ichiro Tanizaki’S In Praise Of Shadows, Kenichiro Otani

The Coastal Review

Building upon comparative principles, this semantic reading of Jun’ichirō Tanizaki’s essay In Praise of Shadows and J.M.G. Le Clézio’s early writings illustrates how both the Franco-Mauritian author and the Japanese writer problematize modern Western perception laden with concepts stifling flexible imagination through the mysterious worldview of light/darkness. They also simultaneously express the hope that another way of life leading to liberation is possible. Delving into the spiritual confinement of the subject, they demonstrate how keeping rich creativity within one’s heart can be an escape from a stagnant society. Albeit in very different mediums, Tanizaki and Le Clézio assert that the …

Generative Ai Is Doomed, Eric Goldman

Marquette Intellectual Property & Innovation Law Review

Eric Goldman delivered this talk as the 2024 Nies Lecture at Marquette University School of Law, in Milwaukee, Wisconsin. The talk compares the recent proliferation of generative AI with the Internet’s proliferation in the mid-1990s. In each case, it was clear that the technology would have revolutionary but uncertain impacts on society. However, the public sentiments toward the two innovations have differed radically. The Internet arrived during a period of widespread techno-optimism, creating a regulatory environment that fostered the Internet’s growth. Generative AI, in contrast, has arrived during widespread techno-pessimism and following decades of conditioning about the dangers of “AI.” …

Beyond The Hype: The Use Of “Artificial Intelligence” In Healthcare And The Legal And Business Risks Associated With This New Technology, Greg Gulick

Marquette Intellectual Property & Innovation Law Review

None.

Tech Addiction: The Legal Limits Of A Growing Concept, Haneen Abu Ghanem

Marquette Intellectual Property & Innovation Law Review

None.

The Laboratory Of Repair: Testing California’S Right To Repair Law In The Post-Analytical Phase, John Wilson

Marquette Intellectual Property & Innovation Law Review

None.

Can Miley Cyrus Really Buy Her Own Flowers: An Analysis Of Answer Songs In Relation To Fair Use, Emmeline Eike

Marquette Intellectual Property & Innovation Law Review

September 16, 2024, Tempo Music Investments LLC filed a copyright infringement complaint against Miley Cyrus. The complaint is due to the striking similarities between Cyrus’s song, Flowers, and Bruno Mars’s song When I Was Your Man. Tempo Music attributes Cyrus’ success with Flowers in 2023 to When I Was Your Man’s existence and not purely from the song itself.  In discussing this lawsuit, this comment explores how likely a fair use claim is to succeed, while also analyzing how the parody fair use defense is currently applied to songwriting. Additionally, it also discussed parodies vs. answer/response songs, specifically what the …

Getting It “Right”: Educators’ Experiences With School Diversity In A Gentrifying Neighborhood, Jennifer B. Ayscue, Kfir Mordechay, Gage F. Matthews, Julie Whetzel

All Faculty Open Access Publications

Schools in gentrifying neighborhoods often experience demographic changes in enrollment. The purpose of this qualitative holistic case study is to describe how leaders and teachers in a diversifying elementary school in a gentrifying neighborhood perceive and experience diversity. Drawing on Turner’s value of diversity framework, we use inductive coding to analyze interviews and also use documents to inform our findings. Although Greenleaf was striving to be intentionally diverse, consensus did not exist about the meaning of “diversity” or the desired form of diversity. Challenges associated with decentering Whiteness and resisting upholding the racial contract existed as educators worked to establish …

The Effectiveness Of Using Machine Learning Techniques To Improve Online Education Advantages, Challenges, And Barrier, M. Samir Abou El-Seoud

Computer Science

In this paper, we are going to analyze the effectiveness of using machine learning (ML) techniques to improve online education. Nowadays, numerous universities and online education providers have expanded their offerings. For the uninitiated, we can simply refer to online education as distance learning facilitated through the Internet and a computer. Online education, as a component of distance learning, is gaining popularity due to its offerings. In recent years, online education has become an important part of contemporary education. It's important because it allows students to learn or get access to study materials without attending a conventional class at a …