Digital Commons Network^™

No Suspicion For Nocarh: A Cautionary Tale Of Anchoring Bias, Nicole Demarco, Julia Allyson Hays, Bonnie Sullivan, Michael Price, Kimberly A. Horii, Shannon Haines

Posters

Introduction: Neonatal onset of cytopenia autoinflammation rash and hemophagocytic lymphohistiocytosis syndrome (NOCARH), a subset of hemophagocytic lymphohistiocytosis (HLH), is a rare and life-threatening condition characterized by uncontrolled immune response. It presents a diagnostic challenge in neonates due to the overlap of clinical features with other conditions, particularly congenital infections. We report a case of NOCARH in a late pre-term neonate, highlighting an atypical age group and the diagnostic difficulty of this syndrome. Case Presentation: A 1 day old ex-35 week er neonate presented to a level 4 NICU with chief complaints of pancytopenia,; an extensive petechialmaculopapular rash of on the …

Design And Implementation Of An Interdisciplinary Course: “Communicable Disease Control And Prevention – Ethics And Laws”, Pei-Chun Chan, Chi-Tai Fang, Yu-Wei Hsieh

Journal of Medical Education

This interdisciplinary course, Communicable Disease Control and Prevention: Ethics and Laws, brings together medical, legal, and public health perspectives to examine the ethical and regulatory challenges of infectious disease governance. Through lectures, case analyses, debates, and simulated public hearings, students–primarily from law, public health, medicine and social science–engage with issues such as isolation, quarantine, vaccination responsibilities, communicable diseases-related stigma, and broader health inequalities. The curriculum emphasizes translating academic knowledge into public reasoning and advocacy, using diverse outputs including oral presentations, debates, and infographic-based policy proposals. By engaging with legal professionals, judges, and aff ected communities, students broaden their perspectives beyond …

A Review Of Common Limitations In Rural-Related Studies In The Peer-Reviewed Literature, Stephanie M. Mathis, Olivia A. Sullivan, Margaret M. Francisco, Nicole Galler, Kate E. Beatty, Michael B. Meit, Chyanne Morrison, Christiana Keinath

ETSU/NORC Rural Health Research Center Policy Briefs

No abstract provided.

The Role Of Liver Macrophages In Viral Liver Pathogenesis, Alexis Brantly, Kyle Yeakle, Michael J. Bouchard, Peter J. Gaskill, Michael R. Nonnemacher

Kimmel Cancer Center Faculty Papers

Liver macrophages play important roles in the pathophysiology of liver fibrosis and hepatocellular carcinoma. However, liver macrophages are a heterogenous population and have differing roles in maintenance of liver function and response in disease. In a healthy liver, macrophages play a critical role in antigen processing, maintaining tolerance to the high levels of gut-derived bacterial products, and regulating inflammation through cytokine response. However, macrophages also play a critical role in liver pathology, specifically in the context of viral infection. The liver is targeted by multiple viruses, including human immunodeficiency virus, hepatitis B virus, and hepatitis C virus, which dysregulate macrophage …

Microbiome Signatures And Inflammatory Biomarkers In Culture-Negative Neonatal Sepsis, Morcos Hanna, Shixia Huang, Matthew Ross, Anaid Reyes, Dimuthu Perera, Anil Surathu, Sara Javornik Cregeen, Joseph Hagan, Mohan Pammi

Faculty and Staff Publications

Overuse of antibiotics is a concern in 'culture-negative sepsis' but it is unclear whether this is due to infection with viruses, fungi or other microbes that are not easily cultured, or whether it results from inflammatory processes. In a prospective study, we enrolled 50 preterm neonates with culture-positive sepsis (CP), culture-negative sepsis (CN), and asymptomatic preterm controls (CO). The microbiome of stool, skin, and blood, including bacterial, viral and fungal components and serum cytokine profiles were evaluated. The microbiome alpha or beta diversity did not differ between CN and CO groups. A MaAsLin analysis revealed increased relative abundances of specific …

Curing The Peasant's Disease : Frank Oldt’S Work And Research On Hookworm Disease In South China, 1905-1926, Jiaying Fu

Lingnan Theses (MPhil & PhD)

While current scholarship on “hygienic modernity” in China focuses on the construction of urban health systems and institutional infrastructures, this study proposes an alternative analytical lens by foregrounding the domain of agricultural health. It aims to investigate how early twentieth-century medical researchers uncovered public health models grounded in China’s agrarian conditions. Taking the case of Frank Oldt (1879–1976), a medical missionary living in Guangdong between 1905 and 1926, this research examines how he identified, interpreted, and sought to mitigate the problem of hookworm disease—a parasitic condition intricately linked to China’s farming practices and rural environmental conditions.

Specifically, this thesis aims …

Epidemiology And Microbiology Of Admission Surveillance Nasal Swabs In A Level Iv Neonatal Intensive Care Unit (Nicu) And Their Association With Subsequent Infections ​, Kedar Tilak, Neena Kanwar, Rangaraj Selvarangan, Venkatesh Sampath

Posters

Background Newborns, especially preterm infants, are highly susceptible to sepsis, a major cause of neonatal morbidity and mortality. Known risk factors include prematurity, low birth weight, prolonged NICU stay, and use of central venous catheters. The link between early nasal colonization (within the first week of life) and later infections is unclear. Although many NICUs screen for Staphylococcus aureus using nasal swabs, the predictive value of early colonization by other Gram-positive and Gram-negative bacteria is not well understood. In our NICU, admission nasal swabs were sent for aerobic cultures to detect these organisms, highlighting the need for further research into …

Fever In The Returned Traveler, Children's Mercy Kansas City

Clinical Pathways

No abstract provided.

Sleep Quality, Emotional Moods, And Cognitive Outcomes Among People Living With Hiv: An Ecological Momentary Assessment Study, Shan Qiao Ph.D., Abhishek Aggarwal, Camryn Garrett, Arielle N’Diaye, Atena Pasha, Irene Esu, Chih Hsiang Yang Ph.D., Xiaoming Li Ph.D.

Faculty Publications

Introduction Although studies have explored the relationship between sleep quality, mood, and cognitive outcomes among people living with HIV (PLWH), few use ecological momentary assessment (EMA) techniques to evaluate within-person associations between sleep quality and emotional/cognitive outcomes among PLWH at the day level. This study investigated the association between previous night’s sleep quality and momentary psychological outcomes in participants’ natural setting. Methods Study participants were PLWH in South Carolina who were at least 18 years old, diagnosed with HIV for at least 2 years, and able to operate a cellphone. Participants were sampled using posters posted in AIDS Service organizations, …

Ahms 270e.50: Medical Ethics, Mary B. Mchugh

University of Montana Course Syllabi, 2021-2025

No abstract provided.

Ahrc 150.01: Respiratory Care Laboratory I, Paul J. Crockford

University of Montana Course Syllabi, 2021-2025

No abstract provided.

Comx 424.B01: Risk, Crisis And Communication, Gregory S. Larson

University of Montana Course Syllabi, 2021-2025

No abstract provided.

A Neutrosophic Causality Analysis (Nca) For Critical Success Factors Of Humanitarian Logistics Management During Disaster, Phi-Hung Nguyen, Lan-Anh Thi Nguyen, Thu-Hang Thi Do, Khanh-Phuong Hoang, Gia Khai Do, Thuy-Tien Thi Le, Hoai-Thu Nguyen

Neutrosophic Sets and Systems

No abstract provided.

Ahrc 252.01: Respiratory Care Review, Paul J. Crockford

University of Montana Course Syllabi, 2021-2025

No abstract provided.

Chest X-Ray Interpretation In The Epico Pediatric Covid-19 Study: Addressing Misconceptions, Luis Miguel Navarro-Ramirez, Pablo Vásquez-Hoyos, María Lucía Mesa-Rubio, Melisa Naranjo Vanegas, Daniela Duarte-Montero, Claudia Burgos, Laura Melissa Mendez, María Margarita Rodriguez, Arianna Martinez, Paola Sanchez, Carolina Tovar, Gabriela Friedrich, Gustavo Adolfo Triana-Rodriguez, Mónica Royero-Arias, Jessica Echeverry, Tamara Gamo, Luz Ángela Moreno, Olga Lucía Baquero, Luz Marina Mejía, Sonia Restrepo-Gualteros, Sergio Moreno-Lopez, Juan Gabriel Piñeros, Carlos Álvarez-Moreno, Alejandro Díaz-Díaz, Iván Felipe Gutierrez, Clara Galvis-Diaz, José Manuel Nieto, Irati Gastesi, Cinta Moraleda, Alfredo Tagarro García, Andrea Ramirez Varela, Epico‐Colombia And Epico‐Aep Working Groups

Faculty, Staff and Student Publications

No abstract provided.

Nrsg 256.01: Pathophysiology, Ginger M. Sillars

University of Montana Course Syllabi, 2021-2025

No abstract provided.

Pubh 613.50: Spatial Epidemiology In Geographic Information Systems (Gis), Erin L. Landguth

University of Montana Course Syllabi, 2021-2025

No abstract provided.

Ahms 270e.01: Medical Ethics, Victor N. White

University of Montana Course Syllabi, 2021-2025

No abstract provided.

Ahrc 129.01: Patient Care And Assessment, Paul J. Crockford

University of Montana Course Syllabi, 2021-2025

No abstract provided.

Ahrc 235.01: Cardiopulmonary Anatomy & Physiology, Paul J. Crockford

University of Montana Course Syllabi, 2021-2025

No abstract provided.

Enhancing Preparedness: A Genetic Study Of Sar-Cov-2 And Other Microbial Public Health Threats In Wastewater From A College Town, Christian N. Hutchinson

Master's Theses

Problem

The SARS-CoV-2 (COVID-19) pandemic revealed both the systemic vulnerabilities of our healthcare system as well as the importance of timely, localized data for informing public health responses. Traditional testing approaches were essential but often failed to capture the full extent of viral spread, especially in those with mild or asymptomatic conditions that relied on at home testing. This underreporting hindered effective allocation of resources and made developing effective intervention strategies difficult. We also realized the potential for wastewater surveillance to be applied to tracking antimicrobial resistance gene markers. Taken together, this approach should have important implications for improving public …

Healthcare Informatics September 2025, Aga Khan University

Department of Chief Medical Information Officer (CMIO) Archives

This issue of the Healthcare Informatics Newsletter provides key updates on the ongoing AKU OneHealth Electronic Health Record (EHR) build and usability phase. It highlights clinical engagement across nursing, anesthesia, pediatrics, OBGYN, oncology, and emergency medicine, as well as progress in analytics, KPIs, and departmental integration. The newsletter also shares insights from leadership messages, usability milestones, academic contributions, and upcoming events.

Evaluation Of Tracheal And Cecal Microbial Composition In Heat Stressed Broilers Supplemented With Phytogenic Additives, Andressa Silveira Stein

Graduate Theses and Dissertations

The rise in global temperatures has become a concern due to its significant impact on the agricultural sector, including poultry production. Heat stress caused by high temperatures directly affects animal welfare, health and productivity, leading to major losses in the poultry sector. In broilers, heat stress affects feed consumption, weight gain, mortality and may also lead to changes in the microbiome, which can increase the predisposition to disease and impact the overall performance of these animals. The aim of this thesis was to reproduce field conditions, simulating an increase in temperature, and to evaluate possible changes in the respiratory and …

Dual Investigations Into Broiler Health: Mitochondrial Gene Expression In Ascites Susceptibility And G-1,25(Oh)₂D₃-Driven Modulation Of Bone And Gut Integrity In Lameness, Layla Hussein Al-Mitib

Graduate Theses and Dissertations

Modern broiler production faces persistent challenges from metabolic and skeletal disorders, particularly ascites and bacterial chondronecrosis with osteomyelitis (BCO), which compromise animal welfare and production efficiency. This dissertation examines two key factors that contribute to these conditions: mitochondrial gene expression associated with pulmonary hypertension syndrome (PHS) and the role of intestinal barrier integrity in mitigating lameness. In the first study, the expression of mitochondrial genes COXII and ATP6 was evaluated in the breast, thigh, and lung tissues of three broiler genetic lines—ascites-susceptible (SUS), ascites-resistant (RES), and unselected relaxed (REL). While no significant expression differences were observed in muscle tissues, SUS …

Advancing U.S. Competitiveness In Agentic Gen Ai: A Strategic Framework For Interoperability And Governance, Satyadhar Joshi

Harrisburg University Other Works

Abstract : The rapid evolution of artificial intelligence has given rise to agentic AI systems—autonomous entities capable of perceiving their environment, making decisions, and executing actions with minimal human intervention. This work provides a systematic analysis of agentic AI frameworks, governance models, and implementation strategies. Drawing on a comprehensive review of the literature, we examine the current state of agentic AI technologies, highlight key challenges in governance, security, and ethical oversight, and compare architectural frameworks for responsible deployment. Our results, illustrated through detailed framework comparisons and governance analyses, demonstrate that while agentic AI holds transformative potential across multiple sectors, notable …

Volatile Pyrethroid Spatial Repellents For Preventing Mosquito Bites: A Systematic Review And Meta-Analysis, Ingrid Chen, Sarah L. Miller, Daniel Msellemu, Aidi G. Lugenge, Johnson Kyeba Swai, Nicole Achee, Marta Andrés, Christopher S. Bibbs, Theeraphap Chareonviriyaphap, J. Derek Charlwood, Greg Devine, Noel Elman, Ulrike Fillinger, Carmen Flores-Mendoza, Seth Gibson, Nicodem Govella, Steven Gowelo, Sebastian Horstmann, Hitoshi Kawada, Daniel Kline, Aaron Lloyd, Neil F. Lobo, Marta F. Maia, Arnold Mmbando, Mara Moreno-Gómez, Amy C. Morrison, Winifrida Mponzi, Emmanuel P. Mwanga, Margaret Njoroge

All Peer-Reviewed Publications

Background: Volatile pyrethroid spatial repellents (VPSRs) can prevent mosquito-borne diseases including malaria and dengue fever, but the use of varied evaluation methods has resulted in a lack of clarity regarding their protective efficacy (PE) against contact with mosquitoes. This systematic review and meta-analysis consolidates the entomological evidence base on the PE of VPSRs against Anopheles, Aedes, and Culex mosquitoes and different test methods used. Methods: We identified studies completed between January 2000 and September 2023 by searching through databases, conference abstracts, and personal correspondences. Included studies were semi-field or field studies that measured the PE of VPSRs using human landing …

Diminished Long-Term Vaccine Antibody Persistence In Perinatally Youth Living With Hiv On Cart, German A Contreras, Morouge M Alramadhan, Gloria P Heresi, Abel Castro, James R Murphy

Faculty, Staff and Student Publications

No abstract provided.

Antimicrobial Resistance Of Clostridioides (Clostridium) Difficile In Cambodia, Lengsea Eng, Papanin Putsathit, Su Chen Lim, Jessica M. Chisholm, Deirdre A. Collins, Archie C.A. Clements, Kefyalew Addis Alene, Thomas V. Riley

Research outputs 2022 to 2026

Background/Objectives: Antimicrobial resistance (AMR) remains a major topic of interest in infectious disease management. We studied AMR in Clostridioides difficile isolated in Cambodia. Methods: Agar dilution susceptibility testing was performed according to the CLSI guidelines to determine minimal inhibitory concentrations (MICs) of 10 antimicrobials for 192 isolates of C. difficile from four populations in Cambodia: hospitalised adults, hospitalised children, children from an outpatient department (OPD), and healthy adolescents in the community. Results: Using the CLSI MIC breakpoints for anaerobes and EUCAST breakpoints for C. difficile, all isolates were susceptible to vancomycin, metronidazole, fidaxomicin, and amoxicillin/clavulanic acid, and none were resistant …

Restricted Social Engagement Is Associated With Depressive Symptoms In Older Chinese Adults: A Nationwide Cross-Sectional Study, Zheng Guo, Yulu Zheng, Yahong Zhu, Huacheng Wang, Jian Geng, Hengrui Liu, Piyong Ma, Lois Balmer, Xingang Li

Research outputs 2022 to 2026

Background and Aims: Social isolation has been linked to depressive symptoms in older adults. Previous studies have shown that greater engagement in social activities is associated with better mental health. However, it remains unclear whether restricted social engagement is related to poorer mental health outcomes. This study examined the association between reduced social activities/networking and the presence of depressive symptoms among community-dwelling older Chinese adults. Methods: During the COVID-19 pandemic, people chose to minimize going out to reduce the risk of infection, creating a natural setting that mimicked a passive intervention of restricted social engagement for community-based individuals. Data were …

Penicillin Adverse Drug Reaction (Historical), Children's Mercy Kansas City

Clinical Pathways

No abstract provided.