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Case Study Report: The Nursing Associate Role Within Education In Practice And Teaching At University Level, Heidi Johnson

South West Clinical School Journal

#400WORDS: NATIONAL NURSING ASSOCIATE SPECIAL EDITION

Urgent Radiotherapy For Superior Vena Cava Syndrome In Metastatic Non-Small Cell Lung Cancer: A Case Report, Arpeet Patel, Nilanjan Haldar, Ida Micaily, Michael Greenberg, Evan Nardone, John A. Lippert, Christopher Fundakowski, Adam C. Mueller

Department of Radiation Oncology Faculty Papers

Superior vena cava (SVC) syndrome is a life-threatening complication of thoracic malignancies, requiring rapid management in the setting of airway compromise or hemodynamic instability. We present a 59-year-old male with metastatic non-small cell lung cancer (NSCLC) who developed superior vena cava syndrome (SVCS) due to compression from a large mediastinal mass identified as metastatic lung adenocarcinoma. His declining respiratory status progressed rapidly, necessitating intensive care. After extensive multidisciplinary collaboration, the patient was determined fit for inpatient radiation therapy and 10 fractions of 300 cGy external beam radiotherapy to the obstructing lesion was planned. However, the patient was unable to lay …

Effective Strategies To Attract And Retain Qualified Hospitality Staff In The Post-Pandemic Caribbean, Rajan Bhattarai

Walden Dissertations and Doctoral Studies

Employee attraction and retention remain critical constraints for Caribbean luxury-wellness resorts in the post-pandemic era. Hospitality and tourism leaders are concerned because persistent vacancy, churn, and extended time-to-competence impair service quality and performance of their organizations. Grounded in the Baldrige Excellence Framework and social exchange theory, the purpose of this qualitative single case study was to explore the effective strategies employed by tourism leaders to attract and retain qualified staff within a Caribbean hospitality organization. Data were collected from five Caribbean leaders (HR director, department manager, and supervisors) using semistructured interviews and analyzing organizational documents. Thematic analysis was used to …

Environmental Risk Assessment Of Textile Waste From Bio-Engineered Fibers In The Fashion Industry, Aayush Pankaj Agarwal, Harshit Soral, Irmak Aktan, Karol Montserrat Gonzalez Saad, Maria Daniela Saa Espinosa, Sheetal Suhas Dhanuka, Yi Yang

Harrisburg University Dissertations and Theses

The global fashion industry generates over 92 million tons of textile waste annually, a figure projected to increase significantly by 2030. Bio-engineered fibers, including bacterial cellulose, mycelium-based leather, and recombinant protein textiles emerge as sustainable alternatives to conventional fibers. Despite their promise, recent evidence suggests that these fibers may pose environmental risks at the end-of-life stage, such as incomplete biodegradation in landfills, microfiber shedding, and chemical leaching from dyes and coatings. The purpose of this study is to examine how these risks are represented through scientific literature, corporate sustainability reports, and policy frameworks, and to identify strategies for integrating risk …

Perceived Effects Of Verbal Orders On In-Patient Medication Reconciliation And Safety: A Multi-Center Cross-Sectional Study, Yahaya Jafaru, Abubakar K. Sahabi, Mohammed M. Sani

Pharmacology and Clinical Pharmacy Research

Medication reconciliation presents significant challenges for healthcare professionals, particularly due to communication gaps that contribute to patient safety incidents. The aim of the study was to investigate the perceived effect of verbal orders on in-patient medication reconciliation and safety. The study was a cross-sectional survey with nurse employees of the three tertiary hospitals in Kebbi State, Nigeria as population of the study. The instrument for the data collection was a 21-items researcher-constructed self-administered questionnaire. Chi-square and binomial regression analysis were used in data analysis. Over two-thirds (70.7%) of the respondents reported a negative perceived effect on the patient’s compliance. The …

Crosstalk Between Gut Microbiota And Antihypertensive Drugs: A Systematic Review, Dhiya'ul Haq, Keri Lestari

Pharmacology and Clinical Pharmacy Research

Hypertension is a multifactorial condition characterized by persistently elevated blood pressure. In addition to genetic and environmental factors, recent studies suggest that the gut microbiota contributes to the development of hypertension and modulates the response to antihypertensive therapy. This review aims to summarize the latest knowledge on the bidirectional interaction between gut microbiota and antihypertensive drugs. Original studies published up to May 2025 on this topic were collected from two online databases: PubMed and Scopus. A total of 220 articles were identified, and 9 articles met the inclusion criteria for further discussion. Three of these included articles discussed how gut …

Anti-Inflammatory Actions Of Trigonella Foenum-Graecum L. In Acute And Chronic Inflammation: Insights From Preclinical Studies, Angel Christella, Dzava P. F. Ismail, Eli Halimah

Pharmacology and Clinical Pharmacy Research

Chronic inflammation is a major factor in various degenerative diseases. The use of non-steroidal anti-inflammatory drugs (NSAIDs) is often the main choice, but long-term side effects such as gastrointestinal irritation and nephrotoxicity limit their use. Therefore, natural alternatives such as Trigonella foenum-graecum (fenugreek) have attracted attention due to their bioactive compound contents with anti-inflammatory properties. This narrative review was conducted through a systematic search of articles from the last 10 years in PubMed and Scopus. Keywords used a combination of MeSH and free terms related to fenugreek and anti-inflammatory agents. In vitro and in vivo studies evaluating the anti-inflammatory effects …

A Predictive Model For Multi- Week Respiratory Risk From Red Tide On Florida’S Gulf Coast., Elmer S. Ochaeta

Computer Science and Engineering Faculty Publications

Florida’s Gulf Coast red tide (Karenia brevis) can put toxins into the air, making people cough, irritating the throat, and worsening asthma or other breathing problems especially when winds blow from the ocean toward the beach. Right now, most public updates don’t really help with the question people actually ask when planning a weekend or vacation: “Will going to or close to the beach be risky in the next few weeks?”.

In this project, I build a weekly early warning system that estimates respiratory risk for specific beaches and predicts that risk 2 to 4 weeks ahead. The study covers …

First Scholars: Enhanced Institutional Support For First Generation College Students, Genevieve Reside

Masters Projects

First-generation college students (FGCS) represent a large proportion of incoming freshmen at higher education institutions. Despite the having a high amount of FGCS, institution supports do not meet the high level of need presented by this student population. Lacking cultural capital that would otherwise be passed along by college-graduated parents, FGCS must navigate unfamiliar college territory on their own, requiring a high volume of support. This project explores the importance of institutional support on education outcomes for FGCS, proposing a comprehensive social and financial support program. The scholarship program, First Scholars, awards increasing scholarship amounts for subsequent years that students …

Expressive Language And Behavior, Bethany J. Butler

Masters Projects

Research has revealed the importance of language and its correlation with behavior. Although language and behavior are both forms of communication, this project explores young children and their relationship with society. Honing in on the essential importance of efficient expressive language to be able to participate in society. Looking at common barriers that may hinder the language process. Exploring Maslow and his hierarchy of needs, and understanding that the basic needs have to be met before having the ability to learn. In summary, the project focused on how to support the increase in language in different stages.

Racial And Ethnic Disparities In Neoadjuvant Chemotherapy Patterns And Outcomes In Early-Stage Her2-Positive Breast Cancer, Inimfon Jackson, Xiudong Lei, Hui Zhao, Rashmi Murthy, Sharon H Giordano, Mariana Chavez-Macgregor

Faculty, Staff and Student Publications

We examined neoadjuvant chemotherapy (NACT) use, pathological complete response (pCR) and the association with overall survival (OS) among patients with early-stage HER2-positive breast cancer (BC). Patients ≥18 years with stage I-III HER2-positive BC from 2010-2022 who had surgery and chemotherapy were identified. Of 195,023 patients treated with chemotherapy, 37.7% received NACT. NACT use increased from 18.6% in 2010 to 63.4% in 2022 (p <  0.001) and pCR rates rose from 21% to 47.6% (p <  0.001). Black patients were less likely to receive NACT (aOR = 0.96;95%CI 0.93-0.99) or achieve pCR (aOR = 0.86;95%CI 0.82-0.90) than White patients. pCR was associated with a reduction in the risk of death (aHR = 0.45;95%CI 0.42-0.48). 3-year OS increased from 91% in 2010 to 95% in 2019 for patients without a pCR (p <  0.001), and from 97% to 99% for patients with pCR (p = 0.002). Further research is needed to understand and address racial and ethnic disparities in treatment access and outcomes.

Using Evidenced-Based Practice To Remove Hyperkeratosis To Improve Wound Healing In Venous Leg Ulcer Patients: A Case Study, Briony Flello

South West Clinical School Journal

#400WORDS: NATIONAL NURSING ASSOCIATE SPECIAL EDITION

Exploring The Impact Of The Nursing Associate Role On Urinary Tract Infections Within An Acute Elderly Mental Health Setting, Ann Mcdonnell

South West Clinical School Journal

#400WORDS: NATIONAL NURSING ASSOCIATE SPECIAL EDITION

Establishing An Adhd Post-Diagnostic Support Group: A Quality Improvement Report, Katie Alexandra Jones

South West Clinical School Journal

#400WORDS: NATIONAL NURSING ASSOCIATE SPECIAL EDITION

Enhancing Patient Centred Care And Safety By Optimising Team Collaboration And Increasing The Nursing Workforce Capacity, Kayley Pooley

South West Clinical School Journal

#400WORDS: NATIONAL NURSING ASSOCIATE SPECIAL EDITION

Establishing An Adhd Post-Diagnostic Support Group: A Quality Improvement Report, Katie Alexandra Jones

South West Clinical School Journal

#400WORDS: NATIONAL NURSING ASSOCIATE SPECIAL EDITION

A Large-Scale, Multi-Site Examination Of Resting State Functional Connectivity In Tinnitus, Sara A. Schmidt, Somayeh Shahsavarani, Rafay A. Khan, Yihsin Tai, Elsa C. Granato, Caterina M. Willson, Pedro Ramos, Paul Sherman, Carlos Esquivel, Fatima T. Husain

Faculty Research, Scholarly, and Creative Activity

Resting state functional connectivity (RS-FC) studies of tinnitus are useful tools for identifying neural mechanisms and potential treatment options for patients. Building on our previous work demonstrating the replicability of RS-FCin individuals with tinnitus and controls, we attempted to investigate the factors leading to published inconsistent findings by examining resting state networks in participant groups across two different study sites: civilians recruited from the University of Illinois Urbana-Champaign; and military-affiliated participants recruited at the Hearig Center of Excellence at Lackland Airforce Base in San Antonio, Texas. Multiple analyses were performed: an overall analysis comparing tinnitus and control participants combined across …

We Need Proper Case Reports And Data To Interpret Reports Of Peri-Operative Deaths In Venezuelan Children, J Robert Sneyd

More Faculty of Health Research

A report describing several perioperative deaths amongst Venezuelan childrenraises substantial clinical concern and demands scientific scrutiny. Rozo L, FrancoOH, Bonilla AJ. Mitochondrial genetic susceptibility to anesthetic neurotoxicityin Venezuelan pediatric patients: A Call for vigilance and further research.https://doi.org/10.29328/journal.ascr.1001091. Archives of Surgery and Clinical Research.2025;9(2):042-4. According to the authors, the affected children experienced severe brain injuries or death following routine surgeries under general anaesthesia with sevoflurane, leading to the hypothesis that an inherited mitochondrial DNA variant may underlie a lethal drug–genome interaction. Whilst any paediatric peri-operative death warrants urgentinvestigation, the extraordinary nature of this claim requires equally compelling evidence. At present, the …

Biodiversity Performance Of Living Wall Systems In Urban Environments: A Uk Case Study Of Plant Selection And Substrate Effects On Multi-Taxa Communities, Paul Henry Lunt, James Buckley, Suzanne Mitchell, Gabriel Thomas, Elek Churella, Thomas Richard Murphy

School of Geography, Earth and Environmental Sciences

Urban densification threatens biodiversity, yet conventional greenspace expansion is constrained by limited land availability. Living wall systems (LWS) offer potential biodiversity enhancement through vertical green infrastructure, though their ecological value remains underexplored. This study evaluated the biodiversity performance of three LWS in Plymouth, UK, using multi-taxa surveys to assess invertebrate communities, bird assemblages, and bat activity. A scoping review of 2638 publications revealed limited research on LWS biodiversity, with only 27% of biodiversity-focused papers referencing specific species. Field surveys employed standardised protocols including flower-visiting pollinator observations, spider assessments, soil invertebrate extraction using Tullgren funnels, acoustic bird monitoring, and bat emergence …

Model For Calculating Impact Force For Individualized Hip Fracture Prediction During A Fall, Alisha Agarwal, Daniel Kargilis, Nishtha Gupta, Michael Chang, Rui Feng, Gregory Chang, Chamith S. Rajapakse

Student Papers, Posters & Projects

Osteoporotic-related weakening of bone is a common cause of hip fractures. The standard of care for the diagnosis and management of osteoporosis is the dual-energy x-ray absorptiometry bone mineral density T-scores. Many individuals considered nonosteoporotic, however, still sustain fractures since these tools do not incorporate vital bone parameters and subject-specific characteristics. The purpose of this work was to (1) develop a simple analytical model for estimating the force exerted on the femur during a fall (i.e., impact force) based on measurable patient metrics and (2) define a quantifiable fracture risk index by comparing finite-element-derived bone strength and impact force, which …

Demonstrating How Consistent Kindness, Presence, And Patient Advocacy Improve Engagement And Dignity In Secure Forensic Mental Health Settings, Patricia Quarshie

South West Clinical School Journal

#400WORDS: NATIONAL NURSING ASSOCIATE SPECIAL EDITION

Case Study Report: The Nursing Associate Role Within Education In Practice And Teaching At University Level, Heidi Johnson

South West Clinical School Journal

#400WORDS: NATIONAL NURSING ASSOCIATE SPECIAL EDITION

Bridging The Gap: Enhancing Healthcare Support Worker Confidence And Skills Through A Nursing Associate Led Study Day, Lindsay Ewing

South West Clinical School Journal

#400WORDS: NATIONAL NURSING ASSOCIATE SPECIAL EDITION

Using Evidenced-Based Practice To Remove Hyperkeratosis To Improve Wound Healing In Venous Leg Ulcer Patients: A Case Study, Briony Flello

South West Clinical School Journal

#400WORDS: NATIONAL NURSING ASSOCIATE SPECIAL EDITION

Demonstrating How Consistent Kindness, Presence, And Patient Advocacy Improve Engagement And Dignity In Secure Forensic Mental Health Settings, Patricia Quarshie

South West Clinical School Journal

#400WORDS: NATIONAL NURSING ASSOCIATE SPECIAL EDITION

Bridging The Gap: Enhancing Healthcare Support Worker Confidence And Skills Through A Nursing Associate Led Study Day, Lindsay Ewing

South West Clinical School Journal

#400WORDS: NATIONAL NURSING ASSOCIATE SPECIAL EDITION

Fgf13 Regulates Vgsc-Independent Cardiomyocyte Impulse Propagation Via Cx43 Trafficking, Lala Tanmoy Das, Mattia Malvezzi, Aravind R Gade, Maiko Matsui, Margaret Mckay, Eric Q Wei, Matea J Zelich, Keon Mazdisnian, Jared Kushner, Bi-Xing Chen, Isabella Distefano, Daniel Roybal, Lin Yang, Lisa Stoll, James C Lo, Marian Kalocsay, Fadi G Akar, Steven O Marx, Geoffrey S Pitt

Faculty, Staff and Student Publications

Background: FHF (fibroblast growth factor homologous factor) variants associate with arrhythmias. Although FHFs are best characterized as regulators of voltage-gated sodium channel (VGSC) gating, recent studies suggest broader, non-VGSC-related functions, including regulation of Cx43 (connexin 43) gap junctions and hemichannels, mechanisms that have generally been understudied or disregarded.

Methods: We assessed cardiac conduction and cardiomyocyte action potentials in mice with constitutive cardiac-specific Fgf13 ablation (cFgf13KO) while targeting Cx43 gap junctions and hemichannels pharmacologically. We characterized FGF13 regulation of Cx43 abundance and subcellular distribution. With proximity labeling proteomics, we investigated novel candidate mechanisms underlying FGF13 regulation of Cx43. …

Periodontal Precision: Diagnostic Skills And Confidence Of Dentists In Asian Countries In Applying The 2017 Efp/Aap Periodontal Disease Classification- A Cross-Sectional Pilot Study, Kamran Ali, Priti Charde, Daniel Zahra, Ewen Mccoll, Tayeb Al Hadeethi, Nader Hamdan

Peninsula Dental School

Background: The classification of periodontal disease published in 2017 by the European Federation of Periodontology (EFP) and American Academy of Periodontology (AAP), provides a framework for diagnosis and treatment. The aim of this study was to evaluate the diagnostic skills and self-perceived confidence of dentists and dental students based in Asian countries in the use of this classification. Methods: A cross-sectional analytic study design was employed. An online questionnaire encompassing four periodontitis cases was used for data collection. A total of 500 participants were invited to provide a diagnosis and rate their confidence for each case. Results: Responses were provided …

Increased Intermembrane Space [Ca2+] Drives Mitochondrial Structural Damage In Cpvt, Shanna Hamilton, Radmila Terentyeva, Roland Veress, Fruzsina Perger, Zuzana Nichtova, Mark Bannister, Jinxi Wang, Sage Quiggle, Rachel Battershell, Matthew Gorr, Sandor Györke, Bum-Rak Choi, Christopher George, Andriy Belevych, György Csordás, Dmitry Terentyev

Department of Pathology, Anatomy, and Cell Biology Faculty Papers

BACKGROUND: Mitochondrial dysfunction caused by abnormally high RyR2 (ryanodine receptor) activity is a common finding in cardiovascular diseases. Mechanisms linking RyR2 gain of function with mitochondrial remodeling remain elusive. We hypothesized that RyR2 hyperactivity in cardiac disease increases [Ca 2+ ] in the mitochondrial intermembrane space (IMS) and activates the Ca 2+ -sensitive protease calpain, driving remodeling of mitochondrial cristae architecture through cleavage of structural protein OPA1 (optic atrophy protein 1).

METHODS: We generated a highly arrhythmogenic rat model of catecholaminergic polymorphic ventricular tachycardia, induced by RyR2 gain-of-function mutation S2236L(Ser2336Leu)(+/-) . We created a new biosensor to measure IMS-[Ca2+ ] …

Functional Vs Anatomical Cortico-Striatal Connectivity In The Macaque Brain, Wei Tang, Megan E Monko, Zoe Liu, Ana M G Manea, Fernando A Ortega, Damyan Hart, Jason Zhou, Jan Zimmermann, Sarah R Heilbronner

Faculty, Staff and Students Publications

The cerebral cortex provides the main input to the striatum, constituting the first step in cortico-basal ganglia loops. Decades of careful anatomical tract-tracing research have established the exquisite topography of each cortical region's projection to the striatum in nonhuman primates. In parallel, neuroimaging research has demonstrated the relationship between cortico-striatal resting-state functional connectivity and specific cognitive, behavioral, psychiatric, and neurological states in humans. However, still unclear is the extent to which functional connectivity recapitulates the specific topographies of cortico-striatal anatomical connectivity. Here, we combined datasets of cortico-striatal anatomical and functional connectivity in macaques to determine the degree of overlap between …