Digital Commons Network^™

The Dynamic Interplay Between Monovalent Salts And Ribosomal Protein S1 In Regulating Rna G-Quadruplex Structure, Chloe M. Martin

Honors Theses

Many remarkable discoveries, especially in the last decade, have shown scientists just how important RNA is. In this study, the secondary structure of RNA, G-Quadruplexes, is the topic of interest and how they are affected by salts and S1 protein. To obtain the S1 protein it was transformed from E. Coli using a bacterial plasmid. The S1 protein was then purified from the bacteria through the use of many purification methods. The monovalent cationic salts used were LiCl and KCl which have different ionic radii size that contributes to the stability of RNA G-Quadruplexes. This stability was observed and affected …

Knowledge Production As Identity Expression: A Third-Space Perspective On Sustainable Careers, Alicja Syska

School of Law, Humanities and Social Sciences

This conceptual paper advances our understanding of sustainable careers by focusing on the knowledge creation activities of third-space practitioners in higher education. Specifically, we apply and extend the Process Model of Sustainable Careers to examine how different forms of knowledge production in three different institutional and national contexts – writing for publication, practice-based expertise, and curriculum development – contribute to career sustainability at the intersection of academic and professional/administrative roles and domains. The critical element of this extension is ‘identity expression’ in the form of knowledge production, which acts as an integrating mechanism that flows through and connects the original …

Diplomacy Derailed: Discrimination’S Detour On Route 40, Gage A. Kivlen

Masters Theses, 2020-current

The 1961 Route 40 campaign in Maryland became a critical battleground where three competing approaches to addressing racial segregation revealed deep contradictions in Cold War America. Route 40, a major highway between Washington D.C. and New York, became an international embarrassment when African diplomats from newly independent nations were repeatedly refused service at restaurants and hotels. This crisis prompted responses from three distinct actors: the Congress of Racial Equality (CORE), which employed grassroots organizing and direct action; the State Department's Special Protocol Service Section (SPSS), which pursued top-down diplomatic solutions; and the Federal Bureau of Investigation (FBI), which conducted extensive …

How To Talk To A Seahorse: Communication In Transmasculine Gestational Experiences As Told Through Narrative, Emerson Armstrong

Communication ETDs

Transmasculine experiences before, during, and after pregnancy were evaluated using focus groups and autoethnographic research. As transgender people are more likely to experience inequality in healthcare encounters, this project aims to shed light on, and counter sensationalized accounts of male pregnancy, as transmasculine gestational individuals sought normalization in their experiences of pregnancy. Seven focus groups consisted of 90 minute sessions, with a total of 15 participants. Transcripts were analyzed using a trans narrative approach to find a greater understanding about identity construction, challenges, and changes around trans pregnancy. Asking about communities and healthcare experiences worked to create a complete picture …

Cardiometabolic And Molecular Adaptations To 6-Month Intermittent Fasting In Middle-Aged Men And Women With Overweight: Secondary Outcomes Of A Randomized Controlled Trial, Ruteja A Barve, Nicola Veronese, Beatrice Bertozzi, Valeria Tosti, Maria Lastra Cagigas, Francesco Spelta, Edda Cava, Laura Piccio, Dayna S Early, Richard D Head, Luigi Fontana

2020-Current year OA Pubs

Intermittent fasting (IF) has gained attention as a potential intervention for cardiometabolic health, though its long-term effects remain unclear. In this randomized clinical trial, we assessed the impact of 6 months of IF on body composition, cardiovascular risk factors, and related molecular pathways in middle-aged (30-65 years) men and women with overweight (BMI 24.8-35 kg/m²). In this trial, 41 participants were randomized to either an intermittent fasting (IF) intervention or to maintain their habitual diet. The primary outcome (circulating CRP concentration) was previously reported; here, we present exploratory analyses focusing on metabolomic and transcriptomic responses. IF led to an 8% …

2025 Fall Commencement, Harding University

Commencement Programs

Program for the Harding University Commencement on December 13. 
Commencement Speaker: Dr. Susan Kehl

Speaking Up Or Helping Out? The Impact Of Gendered Feedback On Voice And Helping Ocbs And Imposter Phenomenon And Self-Confidence, Jacklyn Scymcyk

Theses and Dissertations

Grounded in Self-Discrepancy Theory (Higgins, 1987) and Role Congruity Theory (Eagly & Karau, 2002), this study examines how gendered differences in feedback influence employees’ self-views and subsequent citizenship behaviors. Specifically, the research aimed to investigate how the relative frequency of task performance feedback and contextual performance feedback impacts self-confidence and imposter phenomenon, and how these self-views, in turn, predict voice and helping organizational citizenship behaviors (OCBs), respectively. Initial phases of this study validated measures for perceptions of task and contextual performance feedback frequency, favorability, and adequacy. The final phase used moderated-mediation polynomial regression analyses to test hypotheses. Exploratory cluster …

Protein-Nucleic Acid Language Model-Assisted Design Of Precise And Compact Adenine Base Editor, Jingxuan Ren, Jiawei Yao, Qiuyu Cao, Yinuo Li, Yang Li, Ziyi Zhang, Xiyu Ge, Shengfang Wang, Yang Zhang, Xiaogang Wang, Xiaohui Zhang

Faculty, Staff and Students Publications

Adenine base editors (ABEs) are powerful tools for gene therapy. However, efficient version of ABEs (e.g. ABE8e) always induce excessive bystander and off-target editing events and are large in size, hindering their potential in clinical disease treatment. Here, we develop a pre-trained Protein-Nucleic Acid Constrained Language Model to design ABE8e with high activity, reduced editing window and decreased size. By further engineering, the smallest ABE8e- PNLM-pcABE- with a 27% size reduction, exhibits high activity, precise 3-nt editing window, and reduced off-target events near background level in HEK293T cells. Compared to ABE8e, PNLM-pcABE has up to 133.5-fold precision improvement in pathogenic …

¿Cómo Se Dice, "Liberty And Justice For All Cannot Exist Without Equal Access For All" En Español?, Turner Denise Reynolds

Kentucky Law Journal

No abstract provided.

Prosecutorial Discretion And Digital Democracy, Erin Sheley

Kentucky Law Journal

No abstract provided.

Blindness Through The Looking Glass [Book Review], Mollie Frazier

Disability in LIS (DisLIS)

This review analyzes Gili Hammer’s Blindness Through the Looking Glass: The Performance of Blindness, Gender, and the Sensory Body. This book offers insight into the lives of blind women in Israel and challenges assumptions about beauty, femininity, and gender through interviews and years of Hammer's fieldwork as an anthropologist. She shows how blindness is not defined by what is missing, but by how women use their experiences to shape their own understandings of gender and society. The book explores gender identity, visual culture, and the sensory body, highlighting how blind women navigate a world so centered on visual beauty while …

Affordability And Usability Of Digital Learning Resources In Higher Education: A Case Of Online Mathematics Tutorials For Engineering Students At The University Of Dar Es Salaam, Fatuma S. Ikuja, Idrissa S. Amour, Abdi T. Abdalla

Tanzania Journal of Engineering and Technology (TJET)

Effective learning requires engagements with both learning contents and instructor’s personalized support. Large class sizes often limit opportunities for personalized instruction and timely feedback. Digital resources offer a viable solution to enhanced engagement and independent learning. This study investigated the affordability and usability of online digital learning resources for mathematics tutorials, specifically targeting engineering students at the University of Dar es Salaam. A quasi-experimental research design was adopted, focusing on digitization of undergraduate course: Matrices and Basic Calculus for Non-Majors (MT161). The course was delivered through the Moodle Learning Management System integrating STACK to support Mathematics questions. Data was collected …

Denoising Low Dose Ct Images Using Enhanced Autoencoder Deep Learning Model: A Phantom Study, Ali O. Masoud, Khamis O. Amour, Ahmed M. Jusabani, Adithya Rajnaryanan, Manoj Kumar, Yasir M. Haji, Mwingereza J. Kumwenda

Tanzania Journal of Engineering and Technology (TJET)

Reducing radiation dose in Computed Tomography (CT) inherently leads to increased image noise, which can compromise clinical interpretation. To address this limitation in Low Dose CT images (LDCT), numerous computational techniques particularly convolutional neural networks (CNN) have been explored for CT image enhancement. Various CNN architectures with different convolutional layer designs have been developed to improve image quality. This study evaluates the effectiveness of a developed CNN-based autoencoder for denoising LDCT images while preserving diagnostic integrity. An end-to-end CNN autoencoder with information bottleneck (IB) pipeline was designed and trained using CT phantom images with varying noise levels, aiming to suppress …

Lean Manufacturing Implementation Barriers For Micro, Small And Medium Industries In Tanzania: Fuzzy Analytical Hierarchy Process, Juma M. Matindana, Francis D. Sinkamba, Mussa I. Mgwatu

Tanzania Journal of Engineering and Technology (TJET)

With rising global competition, manufacturing industries are adopting Lean Manufacturing (LM) to stay competitive. However, LM implementation in Africa, especially among micro, small, and medium industries (MSMIs), remains low, with research estimates at just 1%. This study examines the barriers to LM implementation in Tanzanian MSMIs. Data were collected from 243 respondents using survey research and purposive sampling. Descriptive and inferential statistics using SPSS version 27.0.1, along with the Fuzzy Analytical Hierarchy Process (FAHP), were used for analysis. The top five LM barriers for micro industries are lack of training on LM tools, poor understanding of lean philosophy, high investment …

Cost Of Safety: Evidence From Building Construction Projects In Tanzania, Juma M. Matindana, Kamugisha J. Kajumulo, Fatma K. Mohamed

Tanzania Journal of Engineering and Technology (TJET)

Cost of safety is a condition where a project determines the magnitude to which its resources are used for activities that prevent poor safety outcomes, that appraise the safety quality of the project services, and that result from safety failures. Reducing the cost of safety remains a major challenge in Tanzania's construction industry and reflects trends in many developing countries. A positive safety environment in which projects reduce costs associated with safety performance is critical to project success. This study investigates the cost of safety of building construction projects in Tanzania. The questionnaire was distributed to 255 contractor companies managing …

Building Resilience One Connection At A Time: A Guide To Developing Retention Programming On College Campuses, Stephanie Sibley, Rachel Daltry

Journal of Access, Retention, and Inclusion in Higher Education

Despite college students having the potential to be more socially connected than ever before thanks to technology and social media, many students still struggle with isolation, loneliness, and a lack of belongingness and community. These feelings and experiences not only increase the risk for suicidal behavior and diminish resilience, but they can also negatively impact student retention. Outreach programming that targets social connectedness will be described. Specific guidelines developed from first-hand experiences with implementing such programming will be highlighted, and readers will be encouraged to consider how similar programming could be implemented by various offices or personnel at their own …

Bridging The Gap: Exploring The Impact Of Graduate Preparation Programs On Undergraduate Stem Students, Faika Tahir Jan, Thomas Nelson, Travis Chan, Tremayne O. Waller, Cynthia Hampton, Sherif Abdelhamid

Journal of Access, Retention, and Inclusion in Higher Education

This study explores the impact of the "A Step to the Doctorate" (S2D) program on the academic trajectories of undergraduate STEM students, focusing on how it fosters academic success and prepares participants for graduate education. Drawing on data from pre and post surveys and semi structured interviews of 60 participants, the research addresses two primary questions: (1) Which program components do participants find most impactful? Moreover, (2) How has the program influenced their academic aspirations and preparedness for graduate school? The findings highlight that mentorship, peer networking, and targeted workshops are key in boosting academic self-efficacy and enhancing participants’ confidence …

The Success Equation: Scaling The Pivot Framework For Stem & Healthcare Student Success, Ryan Clark, Jarrod Lockhart

Journal of Access, Retention, and Inclusion in Higher Education

Student success in STEM and healthcare increasingly depends on intentional design of equitable, scalable pathways that integrate structured programming, immersive experiential learning, and modern workforce-aligned upskilling. This manuscript introduces the PIVOT Framework— Pathways, Innovation, Vision, Opportunity, and Transformation—as a comprehensive, evidencedriven model for reimagining student success strategies in STEM and healthcare education. The framework emphasizes early engagement, longitudinal support, and competency-based preparation, ensuring students develop the skills and professional identities necessary for success. Drawing from a range of high-impact practices—including paid internships, research-based learning experiences, mentoring structures, digital skills integration, and stackable credentialing—the manuscript demonstrates how coordinated institutional strategies improve …

The Power Of Intentional Programming: Amplifying Student Voices As A Catalyst For Student Engagement At Hbcus, Jason D. Etheridge

Journal of Access, Retention, and Inclusion in Higher Education

Student engagement is a critical factor in retention and success, particularly at Historically Black Colleges and Universities (HBCUs). This study explores the development and implementation of intentional programming designed to foster inclusion, leadership, and academic success at an HBCU in the southeastern United States. Using a student-centered approach, initiatives such as leadership conferences, study halls, and identity-affirming programs were developed to address gaps in student engagement. Through qualitative data collection and student feedback analysis, findings suggest that integrating student voices into programming enhances institutional responsiveness, strengthens campus culture, and improves retention. This study highlights best practices, challenges, and implications for …

Rethinking Academic Integrity: Deconstructing Academic Norms In A Technologically And Culturally Shifting Lanscape, Ilknur Sancak-Marusa

Journal of Access, Retention, and Inclusion in Higher Education

The rise of generative AI use in higher education calls for a critical reexamination of academic integrity, revealing its culturally-constructed and context-dependent nature. While institutions scramble to create generative AI policies, many rely on Western-centric definitions of integrity that overlook the diverse cultural and linguistic students’ backgrounds. Traditional frameworks often misunderstand behaviors like patchwork writing or collaborative learning, viewing them as misconduct rather than culturally influenced practices. This paper argues that academic integrity standards differ across cultures and institutions rather than follow universal principles. As generative AI further complicates ideas of authorship and originality, institutions must move beyond punitive responses …

Editor's Note, John B. Craig

Journal of Access, Retention, and Inclusion in Higher Education

No abstract provided.

Disaster Exercise: Evaluating Mci Triage Training, Michael J. Steflovich Jr, Jodie Stobierski, Alexis Davis, Natasha Pavlinetz, Nela Isic, Nicole Roberson, Earl Best Md

Florida Journal of Emergency Medicine (FJEM)

Abstract

Study Objectives

The primary objective of this study was to evaluate the effectiveness of a didactic lecture-based training on mass casualty incident (MCI) triage performance among first- and second-year medical students. Specifically, the study aimed to measure improvements in overall triage accuracy, as well as reductions in over-triage and under-triage rates for both adult and pediatric patients.

Methods

This study employed a pre-test/post-test design involving 31 participants. Participants completed an electronic pre-test consisting of 30 patient scenarios (20 adult and 10 pediatric) before attending a 40-minute didactic lecture on MCI triage principles. The lecture covered the identification of MCI …

Development Of An Artificial Intelligence Web Based System For Classification Of Tomatoes Disease, Joshua Sokowonci Mommoh, Etinosa Noma-Osaghe, Vera Nimo Timai, Odike Arnold Uchechi, Solomon Obhenbhen Ibharunujele, Blessing Godday

Mansoura Engineering Journal

The development of this platform addresses the challenges associated with traditional tomato disease detection methods as well as the challenges of current machine learning and deep learning models in accurately detecting tomato diseases. Conventional methods of tomato disease diagnosis typically rely on expert evaluation but are time-consuming and susceptible to human mistakes. Incorrect diagnoses of certain diseases could lead to poor control measures, resulting in decreased agricultural productivity. In this research, the PlantVillage dataset, comprising 18,160 tomato leaf images distributed across 10 classes, was used to train two machine learning models, namely, Inception-ResNetV2 and Inception V3. The models were configured, …

Metamaterial-Based Microstrip Antenna For Safe Detection Of Tiny Breast Tumors, Shrouk E. El-Sawy, Mohamed G. Abdelfattah, Nihal F.F. Areed, Ahmed Shaban Samra

Mansoura Engineering Journal

This study describes the construction of a compact microstrip patch antenna (MPA) with a triangular-shaped metamaterial layer for the safe detection of tiny breast tumors at 2.4 GHz. The metamaterial considerably improves the antenna's gain and directivity when compared to typical designs that do not include it, resulting in improved detection performance. The radiating patch of proposed antenna measures 29.3 × 38 × 1.6 mm and has been tested through simulations and experimental tests, exhibiting successful tumor identification in a realistic breast phantom. The results of both calculations and testing demonstrate a sensitivity of 6.643 dB/mm, allowing for precise detection …

Teaching Slit Lamp Funduscopy With A Self-Guided E-Learning Module With Model Eye And Validation Of A Self-Assessment Tool, Irene Pak, Isabell Kassaye, Adam Alyafaie, Albert Xu, Neeti Parikh, Madeline Yung

Journal of Academic Ophthalmology

Background: Slit lamp funduscopy is an essential diagnostic tool used by ophthalmologists to visualize the posterior structures of the eye. However, the fast-paced nature of outpatient care in ophthalmology often limits preceptor teaching opportunities for medical students during clerkships. This challenge is exacerbated by the minimal preclinical exposure to ophthalmology and the technical complexity of the slit lamp examination. Therefore, curricular reform is needed to improve medical student competency in ophthalmic examination skills.

Purpose: To develop a self-guided e-learning module to teach medical students slit lamp funduscopy and evaluate a self-assessment tool for slit lamp funduscopy skills.

Methods …

Potential Cost Savings At A Single Tertiary Care Center Through Implementation Of A 340b-Compliant Multiuse Drop Protocol For Cataract Surgery, Carla Baaklini, Sabrina Duong, Jieon Jenny Kim, Samer Hajji, Aaron D. Webel

Journal of Academic Ophthalmology

The University of Missouri Healthcare system is seeking to implement a multiuse drop protocol for cataract surgeries, allowing preoperative eye drop bottles to be utilized for multiple patients rather than being discarded after single use. This presents an opportunity for reducing medical waste and achieving considerable cost savings. A key challenge, however, lies in maintaining compliance with the 340B Drug Pricing Program, which currently limits our ability to fully adopt this practice. We additionally encountered barriers including infection control concerns and staff adaptation to new workflows. We detail the barriers we have encountered thus far and present a potential 340B-compliant …

2025 Fall Commencement Program: Winona State University, Winona State University

WSU Commencement Programs

This is the Winona State University Fall 2025 commencement program. Commencement was on Friday, December 12, 2025. There were 2 ceremonies at 9:00am and 11:30am.

During the Commencement event, a complete list of graduates was provided online. This program was not published during the Commencement event. This digital copy is maintained in the repository for archival purposes.

In Recent Research: Exosomal And Molecular Regulators Of Browning And Thermogenesis In Adipose Tissues, Merve İnel, Bahadir Öztürk

Turkish Journal of Medical Sciences

This review synthesizes current knowledge on the molecular mechanisms regulating brown, white, and beige adipose tissues, with particular emphasis on the browning process of white adipose tissue. Rather than considering adipose tissue as a passive energy reservoir, this review underscores its active role as a dynamic endocrine and metabolic organ. Brown and beige adipose tissues, recognized for their thermogenic capacity and contribution to energy expenditure, have emerged as promising therapeutic targets for the treatment of obesity, type 2 diabetes, and related metabolic disorders. The review draws upon recent findings on adrenergic signaling, transcription factors, exosomal microRNAs, and other novel regulatory …

Relcovaptan: A Promising Therapeutic Agent In Traumatic Spinal Cord Injury That Acts By Modulating Newly Identified Transcriptional Regulators Of Aquaporins Compared To Tolvaptan, Şeyma İş, Duygu Ceman, Meri̇h İş, Neşe Keser, Şaban Teki̇n

Turkish Journal of Medical Sciences

Background/aim: Every year, hundreds of thousands of people worldwide suffer from traumatic spinal cord injury (tSCI), which causes irreversible damage, edema, and inflammation. Despite its devastating impact, no safe and effective medication is available. Edema formation is one of the earliest pathological events in tSCI, beginning within minutes after injury. Cytotoxic edema progresses to vasogenic edema, exacerbating irreversible damage. Our study aimed to investigate a therapeutic approach targeting cytotoxic edema in the acute phase of tSCI to improve treatment outcomes. Aquaporins (AQPs) are crucial in edema formation and tSCI pathogenesis. Vasopressin, also known as the antidiuretic hormone, modulates Aqp expression …

Preoperative Awareness Of Nasal And Facial Aesthetic Deformities Among Rhinoplasty Candidates, Ağah Yeni̇çeri̇, Nagi̇han Gülhan Yaşar, Burak Hazir, Meli̇h Çayönü

Turkish Journal of Medical Sciences

Background/aim: This study primarily aimed to evaluate the preoperative awareness of nasal and facial anatomical deformities among patients scheduled for primary rhinoplasty. The secondary objective was to assess changes in patients’ self-perception and aesthetic expectations regarding surgical outcomes following preoperative consultation with the surgeon.

Materials and methods: In this prospective cross-sectional study, 56 adult patients seeking primary aesthetic rhinoplasty at a tertiary care center were included. Each participant completed a 10-item anatomical evaluation form. An experienced rhinoplasty surgeon independently evaluated the same parameters. Additionally, participants completed a two-item visual analogue scale (VAS) questionnaire both before and after the preoperative consultation. …