Digital Commons Network^™

Engl 101-094: Intro To Academic Writing, Gabrielle Rossi

Humanities Syllabi

No abstract provided.

Engl 100-003: English Composition: Introduction To Academic Reading And Writing, Kim Chen

Humanities Syllabi

No abstract provided.

Engl 101-013, 074: Intro To Academic Writing, Jung Hae Chae

Humanities Syllabi

No abstract provided.

Engl 101-019: Intro To Academic Writing, Tyler Leli

Humanities Syllabi

No abstract provided.

Engl 101-023, 025, 027: Intro To Academic Writing, Vivian Aladren

Humanities Syllabi

No abstract provided.

Engl 101-065, 067, 083: Intro To Academic Writing, Dawn Smith-Henry

Humanities Syllabi

No abstract provided.

Engl 101-068: Intro To Academic Writing, Carol Bruzzano

Humanities Syllabi

No abstract provided.

Engl 101-059, 064: Intro To Academic Writing, Nancy Burke

Humanities Syllabi

No abstract provided.

Engl 101-101: Intro To Academic Writing, David Tress

Humanities Syllabi

No abstract provided.

Phil 337-001: World Religions, Charles Brooks

Humanities Syllabi

No abstract provided.

Psy 201-001: Introduction To Psychology As A Behavioral Science, Julia Hyland Bruno

Humanities Syllabi

No abstract provided.

Sts 201-003: Understanding Technological Society, Tyler Leli

Humanities Syllabi

No abstract provided.

Blockchain-Based Trusted Traceability And Sustainability Certification Of Leather Products, Ruba Islayem, Haya R. Hasan, Ahmad Musamih, Khaled Salah, Raja Jayaraman

Industrial Engineering: Faculty & Staff Publications

The leather supply chain comprises numerous organizations and stakeholders, particularly when sustainability aspects are taken into account, making it a complex system. The complexity inherent in such systems can lead to inaccurate information, lack of transparency, and limited data provenance. Moreover, there has been a surge in the call for sustainable practices within leather production, propelled by growing environmental consciousness and ethical considerations. In this paper, we address these challenges by proposing a blockchain-based solution designed to ensure trusted and secure traceability and sustainability throughout the entire life cycle of leather products. By harnessing the inherent capabilities of Ethereum smart …

Er Stress Tolerance Is Regulated By Copper-Dependent Perk Kinase Activity., Sarah E. Bond Newton, Xinglong Shi, Noah R. Beratan, Julia Perhacs, Jitendra K. Arya, Margaret K. Bond, Tali Gidalevitz, Cagla Akay-Espinoza, Donita C. Brady, Kelly L. Jordan-Sciutto

Farber Institute for Neuroscience Faculty Papers

Pancreatic/PKR-like endoplasmic reticulum (ER) kinase (PERK) is a kinase that, in response to ER stress, mediates dual homeostatic and pro-apoptotic signaling. Thus, intricate regulation is required for physiological function. Attempts to modulate PERK activity have shown that the determinants of adaptive vs. maladaptive signaling remain ambiguous. Here, with purified protein, we provide evidence that PERK binds copper, identifies residues required for interaction, and demonstrates that copper is necessary for kinase activity. Furthermore, cellular PERK activity can be modulated via copper availability, and this regulatory relationship can be manipulated to dictate ER stress tolerance. Critically, these phenomena translate to phenotypes in …

Workplace Tug-Of War: The Pennsylvania Supreme Court Weighs Competing Interests With New Cause Of Action To Protect At-Will Employees From Third-Party Interference In Salsberg V. Mann, Alysse Danyi

Villanova Law Review (1956 - )

No abstract provided.

The Glass Menagerie, Tennessee Williams

Taylor Theatre Playbills

The playbill for Taylor University's performance of The Glass Menagerie by Tennessee Williams.

Performed September 25-28, 2025 in the Mitchell Theatre at Taylor University.

At its heart, The Glass Menagerie is a story about the grace that vulnerability makes possible. The Wingfield family—Tom, Amanda, and Laura—are fragile, flawed, and fiercely human. Their lives are marked by disappointment and desire, yet Williams invites us to approach them with tenderness. Laura’s glass animals, so delicate and beautiful, are not just a metaphor for her own inner world but for the human spirit itself—easily broken, but capable of reflecting light in ways that …

Adverse Childhood Experiences: How They Shape Employees' Perceptions, Experiences, And Performance In The Workplace, Marcia A. Beasley

Doctoral Dissertations and Projects

The influence of Adverse Childhood Experiences (ACEs) has been well researched, and the lifelong consequences of medical conditions have been documented. Recently, research has linked mental health concerns to ACEs, including depression, anxiety, and health risk behaviors. ACEs occur during important stages of childhood development and can disrupt these stages, leading to children learn maladaptive coping skills. The resultant maladaptive behaviors that are developed as a response to maltreatment may also hinder social relationships in adulthood. Given this, research is lacking on the influence of ACEs on perceptions in the workplace, especially from the employee’s perspective. This qualitative phenomenological study …

Evolutionary Loss Of An Antibiotic Efflux Pump Increases Pseudomonas Aeruginosa Quorum Sensing Mediated Virulence In Vivo, Sheryl E Fernandes, Humberto Ortega, Mylene Vaillancourt, Anna Clara M Galdino, Aleksandr Stotland, Kyu Shik Mun, Diane Aguilar, Yohei Doi, Janet S Lee, Elizabeth B Burgener, Jeffrey E Barrick, Jeffrey W Schertzer, Peter Jorth

2020-Current year OA Pubs

Antibiotic resistance is a threat to human health, yet recent work highlights how loss of resistance may drive pathogenesis in some bacteria. In two recent studies, we found that β-lactam antibiotics and nutrient stresses faced during infection selected for genetic inactivation of the Pseudomonas aeruginosa antibiotic efflux pump mexEFoprN. Unexpectedly, efflux pump mutations increased P. aeruginosa virulence during infection; however, neither the prevalence of mexEFoprN inactivating mutations in real human infections, nor the mechanisms driving increased virulence of efflux pump mutants are known. We hypothesized that human infection would select for virulence enhancing mutations. Using genome sequencing of clinical isolates, …

Untangling The Roles Of Pulmonary Vagal Afferent Subsets With Inhaled Irritants, Teresa Darcey

USF Tampa Graduate Theses and Dissertations

The sensory nerves in the airways directly regulate critical defenses and indirectly regulate vital gas exchange. Airway function is largely controlled by the autonomic nervous system, and our understanding of its sensory regulation is directly connected to our ability to treat respiratory and cardiovascular pathologies. Airway sensory afferents are heterogeneous with respect to their electrophysiological properties, peptidergic capacity, and stimuli sensitivity, which at least in part dictate some of their various functions. There is evidence that embryological origin impacts reflex function: activation of the neural crest-derived population of sensory afferents has been shown to evoke the cough reflex whereas activation …

Prokaryotic Expression Of Recombinant Plectasin Optimization Of High-Density Fermentation Conditions And Antibacterial Activity, Su Yan, Li Rong

Food and Machinery

[Objective] To construct a recombinant strain expressing the antimicrobial peptide Plectasin, optimize the high-density fermentation conditions of the recombinant strain, and evaluate the antibacterial activity of the purified recombinant peptide produced under optimized conditions. [Methods] To improve soluble expression of the target protein, the plectasin gene was synthesized and optimized based on codon preference of the prokaryotic expression system with signal peptide deletion. The optimized gene was cloned into the pET32a(+) expression vector to construct the recombinant plasmid pET 32a-plectasin, which was transformed into Escherichia coli BL21(DE3)/pLysS competent cells. Single-factor and orthogonal experiments were designed to optimize the parameters of …

The Cowl - V. 89 N. 2 - September 25, 2025

The Cowl

The Cowl - student newspaper of Providence College. Vol. 89 No. 2 - September 25, 2025. 16 pages.

Spectator 2025-09-25, Editors Of The Spectator

The Spectator

No abstract provided.

Spartan Daily, September 25, 2025, San Jose State University, School Of Journalism And Mass Communications

Spartan Daily, 2025

Volume 165, Issue 15

Anti-Aging Effects Of Acid-Extracted Laminaria Japonica Polysaccharides On Caenorhabditis Elegans, Wang Yanying, Xu Meigui, Zhao Pei, Chen Huibin, Huang Luqiang

Food and Machinery

[Objective] To study the anti-aging effects of kelp (Laminaria japonica) polysaccharides. [Methods] Polysaccharide is obtained from kelp by acid-assisted extraction methods. Based on the aging model of Caenorhabditis elegans, the animal's lipofuscin, reactive oxygen species (ROS), antioxidant capacity, and aging-related gene expression are analyzed to evaluate the effects of kelp polysaccharides on their life span, motility, and stress resistance. [Results] Compared with the control group, acid-extracted kelp polysaccharides (AKP) with different mass concentrations improve the life span, mobility, and stress resistance of C.elegans. Specifically, AKP significantly reduces the lipofuscin content and ROS levels, while increasing the activities of catalase and …

Approach To Ophthalmic Surgery Involving The Anterior Vitreous: A Clinical Practice Update From The American Society Of Retina Specialists, Matthew R Starr, Christina Y Weng, Lejla Vajzovic, Kevin J Blinder, Judy E Kim, J Michael Jumper

Faculty, Staff and Students Publications

When encountering diseases of the anterior vitreous and peripheral retina (ie, the "middle segment" of the eye), vitreoretinal (VR) surgeons are specifically trained in surgical techniques for managing the vitreous and visualizing the peripheral retina during anterior vitrectomy, and therefore they are well equipped to address the complications of surgery involving the anterior vitreous space. This clinical update reviews and compares the current literature discussing techniques and patient outcomes related to complete pars plana vitrectomy versus incomplete, subtotal pars plana vitrectomy, and addresses the proposition of developing an abridged training curriculum for non-VR surgeons to acquire the knowledge and skills …

Lysosomes Signal Through The Epigenome To Regulate Longevity Across Generations, Qinghao Zhang, Weiwei Dang, Meng C Wang

Faculty, Staff and Students Publications

The epigenome is sensitive to metabolic inputs and crucial for aging. Lysosomes act as a signaling hub to sense metabolic cues and regulate longevity. We find that lysosomal metabolic pathways signal through the epigenome to regulate transgenerational longevity in Caenorhabditis elegans. Activation of lysosomal lipid signaling and lysosomal adenosine monophosphate-activated protein kinase (AMPK) or reduction of lysosomal mechanistic-target-of-rapamycin (mTOR) signaling increased expression of a histone H3.3 variant and increased its methylation on K79, leading to lifespan extension across multiple generations. This transgenerational pro-longevity effect required intestine-to-germline transportation of histone H3.3 and a germline-specific H3K79 methyltransferase, and was recapitulated by …

Synthesis, Structure-Activity Relationships, And Antitumor Activities Of Quinoxiline-Containing Inhibitors Of The Protein-Protein Interactions Between Transcription Coactivator Af9/Enl And Dot1l/Af4, Chandra Bhushan Mishra, Xin Li, Bala Krishna Moku, Sehun Kwak, Dnyaneshwar N Garad, Yongcheng Song

Faculty, Staff and Students Publications

Mixed lineage leukemia (MLL) gene rearrangements cause ~75% of acute leukemia in infants and 5-10% in children and adults with poor clinical outcomes. Protein-protein interactions (PPI) between frequent MLL fusion partners AF9/ENL and AF4 or histone methyltransferase DOT1L are drug targets for MLL-rearranged (MLL-r) leukemia. Sixty-seven quinoxiline compounds were synthesized and tested for their ability to inhibit such PPIs. Compounds 16, 17, 59 and 63 were found to be potent inhibitors with IC50 values of 0.35-1.5 μM. Structure-activity relationships are discussed. Potent inhibitors can suppress expression of MLL target genes Myc and Meis1 and selectively block proliferation of MLL-r and …

Antibacterial Activity Of Zno/Geopolymer Composite Granules And Their Potential Application In Water Treatment, Ziyan Tirta Maulitia, Putri Nur Angelina, Pipit Erlita Sari, Sri Sugiarti, Irma Isnafia Arief, Zaenal Abidin

Makara Journal of Science

Water pollution has become a major global concern owing to its complexity and widespread impact. Staphylococcus aureus (S. aureus) and Escherichia coli (E. coli) are the most common bacterial contaminants in water sources, which pose significant threats to public health. To mitigate water contamination by these pathogenic microorganisms, developing and implementing effective water treatment technologies are essential. A promising approach involves using antibacterial water filtration systems. Herein, zinc oxide (ZnO) nanoparticles were synthesized via hydrothermal and precipitation methods as antibacterial agents for water treatment. These preparation methods required considerably low synthesis time. A capping agent was …

Montana Kaimin, September 25, 2025, Students Of The University Of Montana, Missoula

Montana Kaimin, 1898-present

Student newspaper of the University of Montana, Missoula.

Sequence And Phylogenetic Analysis Of Citrus Maxima (Burm.) Merr. From Tomini Bay, Sulawesi Island, Based On The Maturase K Gene, Brenda Febrina Zusriadi, Novri Youla Kandowangko, Febriyanti Febriyanti

Makara Journal of Science

This study was conducted in the coastal area of Tomini Bay, Sulawesi Island, and it focused on Citrus maxima, a plant known for its unique fruit flesh colors, which range from yellow to pink, and its varying leaf stalk wings. The study aimed to analyze the variations in maturase K (matK) sequences, molecular characteristics, and phylogenetic relationships of two C. maxima samples from Tomini Bay compared to other C. maxima and Citrus species using data available in GenBank. The study utilized DNA barcoding with matK molecular markers, followed by phylogenetic tree construction using the maximum likelihood method …