Digital Commons Network^™

Dairy And Food Science Student Newsletter, October 8, 2025, Department Of Dairy And Food Science

Dairy and Food Science Student Newsletter

No abstract provided.

How Frontline Communities Are Protecting Srhr Amid Climate Change: Community Solutions And Regional Insights—Slide Deck, Mary Nicholaus, Reinhard Bonke Nyandire, Jacinter Amadi

Sexual and Reproductive Health, Rights, and Choices

No abstract provided.

The Lumberjack, October 08, 2025

Cal Poly Humboldt's Student Newspaper

The student newspaper of Humboldt State University.

The Reciprocity Of Misfortune: The Little Tradition Of Disasters In The Philippines, Greg Bankoff, Bianca Angelien Aban Claveria, David Lozada Iii, Camille L. Silva

History Department Faculty Publications

Just as there is a great and little tradition in religion and civilization, there is a great and little tradition in disaster. This article explores the origins of community resilience in rural areas of the Philippines based on local reciprocity and cooperation and how ­ these customary practices form the basis of national disaster risk-­reduction policies. The endless strug­gle to feed and shelter a family and contend with repeated hazards, whether natu­ral or human-­induced, promotes collective action. There is a need to cooperate with neighbors, a web of dyadic and community relationships born out of necessity that constitutes a “reciprocity …

Daily Eastern News: October 08, 2025, Eastern Illinois University

Daily Eastern News: 2025-2026

No abstract provided.

Clinical Utility Of Diffusion Tensor Imaging In Sport-Related Concussion: A Systematic Review, Shiv Patil, Rithvik Kata, Serhat Aydin, Mert Karabacak, Konstantinos Margetis, Sotirios Bisdas

Student Papers, Posters & Projects

OBJECTIVE: Sport-related concussion (SRC) is a prevalent form of traumatic brain injury that is associated with long-term neurological and psychiatric impairment, particularly among athletes with a history of repetitive concussions. The biological variability of SRC's impact on the brain, as well as a lack of objective biomarkers to diagnose and prognosticate concussion, has prompted interest in advanced neuroimaging methods such as diffusion tensor imaging (DTI). By measuring disruptions in water diffusivity due to head trauma, DTI can detect alterations in white matter integrity that are not visualized by conventional imaging methods. This systematic review aims to synthesize major trends and …

Tyler Dow, Mark Naison, Stephanie Robinson-Ramirez

Oral Histories

Tyler Dow is an actor, rapper, and activist from the Bronx, interviewed here in conversation with Doctor Mark Naison and Stephanie Robinson Ramirez. A 33 year old from Co-op City—the largest housing development in the United States—Tyler gives his perspective on the art and cultural scene of his neighborhood during the turn of the twenty-first century.

Beginning with the background of his familial ties to Co-op City, Dow explains that the first twenty five years of his life were spent in one of the neighborhood’s many high-rise apartments. He describes Co-op City as a proudly middle-class community, one that residents …

Lagomorph Spotlight Survey Results, Johan Du Toit, Shantell Garrett

Browse all Datasets

Results of lagomorph spotlight surveys conducted in the foothills of the Henry Mountains, south-central Utah, over 2014-2022.

Multimodal Reprogramming Of The Tumor Microenvironment By Mmr And Dual Checkpoint Blockade In Hepatocellular Carcinoma Models, Mulu Z. Tesfay, Aleksandra Cios, Khandoker Usran Ferdous, Randal S. Shelton, Bahaa Mustafa, Camila C. Simoes, Murat Gokden, Isabelle R. Miousse, Kimberly J. Krager, Marjan Boerma, Alicja Urbaniak, Anuradha Kunthur, Sri Obulareddy, Joshua M. Eichhorn, Steven R. Post, Jean Christopher Chamcheu, Omeed Moaven, Chiswili Y. Chabu, Dan G. Duda, Matteo Conti, Bruno Nardo, Rang Govindarajan, Martin E. Fernandez-Zapico, Lewis R. Roberts, Mitesh J. Borad, Martin J. Cannon, Alexei G. Basnakian, Bolni M. Nagalo

School of Graduate Studies Faculty Publications

Hepatocellular carcinoma (HCC) is a leading cause of cancer-related death worldwide, thus, there is an urgent need to develop more effective therapeutic options for this dismal condition. Tumor-infiltrating lymphocytes (TILs) are associated with improved response to immune checkpoint blockade in HCC, but their low abundance in most cases limits their therapeutic efficacy. Here, we demonstrate, in mice, that low-dose intratumoral immunovirotherapy with the trivalent measles, mumps, and rubella vaccine (MMR) induces superior tumor-growth delay and extended host survival compared to individually administered vaccines for measles, mumps, or rubella viruses. Further, our results show that MMR therapy synergizes with PD-1 and …

Synthetically Expressive: Evaluating Gesture And Voice For Emotion And Empathy In Vr And 2d Scenarios, Haoyang Du, Kiran Chhatre, Christopher Peters, Brian Keegan, Rachel Mcdonnell, Cathy Ennis

Research Outputs: 2025-Present

The creation of virtual humans increasingly leverages automated synthesis of speech and gestures, enabling expressive, adaptable agents that effectively engage users. However, the independent development of voice and gesture generation technologies, alongside the growing popularity of virtual reality (VR), presents significant questions about the integration of these signals and their ability to convey emotional detail in immersive environments. In this paper, we evaluate the influence of real and synthetic gestures and speech, alongside varying levels of immersion (VR vs. 2D displays) and emotional contexts (positive, neutral, negative) on user perceptions. We investigate how immersion affects the perceived match between gestures …

Apostel-R Recommendations For Reporting Retinal Optical Coherence Tomography Studies In Rodents, Frederike Cosima Oertel, Delia Cabrera Debuc, Peter A. Calabresi, Mei Chen, Christian Cordano, Michael Dietrich, Nicolas Feltgen, Oliver Gramlich, Ari J. Green, Janos Groh, Su-Chun Huang, Benjamin Knier, Thomas Korn, Letizia Leocani, Anat Loewenstein, Christian Van Oterendorp, Tunde Peto, Sven Schippling, Leopold Schmetterer, Steffen Schmitz-Valckenberg, Mathias W. Seeliger, Kenneth S. Shindler, Joel Schuman, Mustafa Sindi, Adnan Tufail, Jui-Kai Wang, Sebastian Wolf, Yuyi You, Martin Zinkernagel, Wolf Lagrèze, Philipp Albrecht

Department of Medicine Faculty Papers

BACKGROUND AND OBJECTIVES: Retinal optical coherence tomography (OCT) in rodent models has been used to longitudinally image retinal changes, to define end points for more costly or time-consuming experiments, and to better understand the pathophysiology underlying OCT findings in human diseases. No standardization of rodent OCT reporting currently exists. Here, we aim to establish consensus recommendation for reporting results from retinal OCT studies in rodents.

METHODS: Initial recommendations were developed based on the APOSTEL criteria for quantitative OCT reporting in humans by a core team. Using a modified Delphi process, an expert panel of rodent OCT researchers (N = 31) …

Spartan Daily, October 8, 2025, San Jose State University, School Of Journalism And Mass Communications

Spartan Daily, 2025

Volume 165, Issue 20

Isu Philharmonia String Orchestra: October 8, 2025, Samuel Chen

School of Music Programs

This is the eighteenth program of the 2025-2026 season.

Kemp Recital Hall

October 8, 2025

Wednesday Evening

7:30 p.m.

Interoperability As A Catalyst For Digital Health And Therapeutics: A Scoping Review Of Emerging Technologies And Standards (2015–2025), Kola Adegoke, Abimbola Adegoke, Deborah Dawodu, Akorede Adekoya, Ayoola Bayowa

Health & Biomedical Sciences Faculty Publications

Background: Interoperability is fundamental for advancing digital health and digital therapeutics, particularly with the integration of technologies such as artificial intelligence (AI), blockchain, and federated learning. Low- and middle-income countries (LMICs), where digital infrastructure remains fragmented, face specific challenges in implementing standardized and scalable systems. Methods: This scoping review was conducted using the Arksey and O’Malley framework, refined by Levac et al., and the Joanna Briggs Institute guidelines. Five databases (PubMed, Scopus, IEEE Xplore, ACM Digital Library, and Google Scholar) were searched for peer-reviewed English language studies published between 2015 and 2025. We identified 255 potentially eligible articles and selected …

Synthetically Expressive: Evaluating Gesture And Voice For Emotion And Empathy In Vr And 2d Scenarios, Haoyang Du, Kiran Chhatre, Christopher Peters, Brian Keegan, Rachel Mcdonnell, Cathy Ennis

Conference papers

The creation of virtual humans increasingly leverages automated synthesis of speech and gestures, enabling expressive, adaptable agents that effectively engage users. However, the independent development of voice and gesture generation technologies, alongside the growing popularity of virtual reality (VR), presents significant questions about the integration of these signals and their ability to convey emotional detail in immersive environments. In this paper, we evaluate the influence of real and synthetic gestures and speech, alongside varying levels of immersion (VR vs. 2D displays) and emotional contexts (positive, neutral, negative) on user perceptions. We investigate how immersion affects the perceived match between gestures …

Messages From The Provost, Georgia Southern University

Messages from the Provost

• Message from the Provost

• GS professor awarded NSF grant to advance protein imaging research

• GS students partner with NASA to develop tech for deep-space missions

• GS post-baccalaureate program helps next generation of coastal scientists wade into research

• Fashion Merchandising student tailors her future following Tyler Perry Studios internship

A Neuroimmune Cerebral Assembloid Model To Study The Pathophysiology Of Familial Alzheimer's Disease, Andrea Becerra-Calixto, Anik Banerjee, Huihui Fan, Chunfeng Tan, Eunyoung Lee, Louise D Mccullough, Juneyoung Lee

Faculty, Staff and Student Publications

Alzheimer's disease (AD) is the leading cause of dementia globally. The accumulation of amyloid and tau proteins, neuronal cell death and neuroinflammation are seen with AD progression, resulting in memory and cognitive impairment. Microglia are crucial for AD progression as they engage with neural cells and protein aggregates to regulate amyloid pathology and neuroinflammation. Recent studies indicate that microglia contribute to the propagation of amyloid beta (Aβ) via their immunomodulatory functions including Aβ phagocytosis and inflammatory cytokine production. Three-dimensional cell culture techniques provide the opportunity to study pathophysiological changes in AD in human-derived samples that are difficult to recapitulate in …

Synaptic Transmission Promotes Brain Metastatic Outgrowth In Breast Cancer, Jayanta Mondal, Patrick Nylund, Prit Benny Malgulwar, William E Johnson, Jason T Huse

Faculty, Staff and Student Publications

This work demonstrates that normal neuron-to-neuron signaling machinery is hijacked by metastasizing cancer cells during their outgrowth in the central nervous system.

Quiescent Oxphos-High Triple-Negative Breast Cancer Cells That Persist After Chemotherapy Depend On Bcl-Xl For Survival, Slawomir Andrzejewski, Marie Winter, Leandro Encarnacao Garcia, Olusiji Akinrinmade, Francisco Madeira Marques, Emmanouil Zacharioudakis, Anna Skwarska, Julio Aguirre-Ghiso, Marina Konopleva, Guangrong Zheng, Susan A Fineberg, Daohong Zhou, Evripidis Gavathiotis, Tao Wang, Eugen Dhimolea

Faculty, Staff and Student Publications

The persistent residual tumor cells that survive after chemotherapy are a major cause of treatment failure, but their survival mechanisms remain largely elusive. These cancer cells are typically characterized by a quiescent state with suppressed activity of MYC and MTOR. We observed that the MYC-suppressed persistent triple-negative breast cancer (TNBC) cells are metabolically flexible and can upregulate mitochondrial oxidative phosphorylation (OXPHOS) genes and respiratory function ("OXPHOS-high" cell state) in response to DNA-damaging anthracyclines such as doxorubicin, but not to taxanes. The elevated biomass and respiratory function of mitochondria in OXPHOS-high persistent cancer cells were associated with mitochondrial elongation and remodeling, …

Structural Variation, Selection, And Diversification Of The Npip Gene Family From The Human Pangenome., Philip C. Dishuck, Katherine M. Munson, Alexandra P. Lewis, Max L. Dougherty, Jason G. Underwood, William T. Harvey, Pinghsun Hsieh, Tomi Pastinen, Evan E. Eichler

Manuscripts, Articles, Book Chapters and Other Papers

The NPIP gene family is among the most positively selected gene families in humans/apes and drives independent duplication in primate lineages. These duplications promote genetic instability, leading to recurrent disease-associated microduplication and microdeletion syndromes. Despite its importance, little is known about its function or variation in humans, as short-read sequencing cannot distinguish high-identity duplications. Using long-read assemblies of 169 human haplotypes, we find extreme variation in the content and organization of NPIP loci. We identify fixed and polymorphic paralogs and observe ongoing positive selection. With long-read RNA sequencing (RNA-seq), we create paralog-specific gene models, the majority of which were not …

Gabaergic Interneurons Contribute To The Fatal Seizure Phenotype Of Cln2 Disease Mice, Keigo Takahashi, Nicholas R. Rensing, Elizabeth M. Eultgen, Letitia L. Williams, Sophie H. Wang, Hemanth R. Nelvagal, Steven Q. Le, Marie S. Roberts, Balraj Doray, Edward B. Han, Patricia I. Dickson, Michael Wong, Mark S. Sands, Jonathan D. Cooper

2020-Current year OA Pubs

The cellular etiology of seizures in CLN2 disease, a childhood-onset neurodegenerative lysosomal storage disorder caused by a deficiency of tripeptidyl peptidase 1 (TPP1), remains elusive. Given that Cln2R207X/R207X mice display fatal spontaneous seizures and an early loss of several cortical GABAergic interneuron populations, we hypothesized that these 2 events might be causally related. To study the cell-autonomous effects of interneuron-specific TPP1 deficiency, we first generated transgenic mice expressing loxP-flanked lysosomal membrane-tethered TPP1 (TPP1LAMP1 mice) on the Cln2R207X/R207X genetic background, and then crossed TPP1LAMP1 mice with Vgat-Cre mice. These Vgat-Cre; TPP1LAMP1 mice accumulated storage material in cortical and striatal interneurons. Vgat-Cre; …

Disclosure And The Pace Of Drug Development, Colleen Cunnningham, Florian Ederer, Charles Hodgson, Zhichun Wang

Cowles Foundation Discussion Papers

Policies that mandate disclosure of innovative project outcomes aim to increase innovation by limiting wasteful duplicative innovation. Yet, such policies change not only the ex-post information environment but also firms' ex-ante innovation incentives. Firms may slow down their own innovation efforts in anticipation of increased disclosure by others. We examine the innovation-related impacts of the 2017 FDA Final Rule amendment, which mandates disclosure of clinical trial results for pharmaceutical firms. We show that the policy hastened and increased disclosure of results for clinical trials post-completion, but also increased the time to completion of clinical trials, the time between early phases …

Transcriptional Responses Of Mouse Proximal Colon And Colonoids During Early Whipworm Infection, Hyeim Jung, Joseph F Urban, Bruce A Rosa, Makedonka Mitreva

2020-Current year OA Pubs

Trichuriasis, caused by the parasitic nematode

Hydroxyapatite Microspheres Induce Durable Pleurodesis And Are Rapidly Cleared By Pleural Osteoclasts, Yusuke Tanaka, Yuki Takahashi, Yuma Shindo, Lori B. Pitstick, Steven L. Teitelbaum, Wei Zou, Xiangning Wang, Jason C. Woods, Kathryn A. Wikenheiser-Brokamp, Francis X. Mccormack

2020-Current year OA Pubs

Talc pleurodesis is highly effective for preventing recurrence of pneumothorax and pleural effusion, but it can be complicated by dissemination, acute lung injury, lead exposure, and foreign body-induced chronic inflammation and pain. Our objective is to develop a safe, biodegradable, contaminant-free particle for pleurodesis. We used mouse models of pneumothorax and malignant pleural effusion to compare the efficacy and safety of pleurodesis with talc and hydroxyapatite microspheres (HAM). Intrapleural instillation of microspheres induced pleural adhesions, fibrosis, and symphysis as effectively as talc and resulted in more durable protection from experimental pneumothorax. HAM and talc both induced an osteoclastogenic, inflammatory, and …

Bacillus Sp. Sw14 Isolated From Arid Mangroves Sediments Enhances Tomato Plant Growth: Insights From Genome Analysis And Greenhouse Evaluation, Balamurugan Sadaiappan, Qurban Ali, Mahideen Afridi, Munawwar Ali Khan, Sunil Mundra

All Works

Mangroves grow in arid regions with high temperatures, low precipitation, and evaporation. Despite low humidity and high salt concentration, these arid mangroves support diverse microorganisms, including salt-and temperature tolerant. The bacteria isolated from these arid mangroves have potential applications in arid agronomy, which alleviate plant stress and enhance plant growth. In this study, we characterize the genome of previously reported PGP and stress-tolerating bacteria, Bacillus sp. SW14, isolated from mangrove sediments of Umm Al Quwain, United Arab Emirates. Further, we investigated its effects on tomato seed germination and plant growth. Genome size of the strain SW14 is 4.25 MB, with …

What Can Bird Poop Teach Us About The History Of U.S. Imperialism?: Guano Islands And Manifest Destiny Beyond Continental Borders, Eliot Fackler

The Councilor: A National Journal of the Social Studies

In high school and college history courses, Manifest Destiny is often taught as a period when the United States expanded across the North American continent in the decades before the Civil War. This article outlines an inquiry-driven lesson examining the Antebellum guano rush and its devastating consequences to show that Manifest Destiny was also characterized by extracontinental imperial ambitions. It highlights the lasting impacts of the 1856 Guano Islands Act and links the guano rush to subsequent empire-building efforts, U.S. militarism, and ecological destruction. The article provides relevant background history, descriptions of possible class activities and assessments, and options for …

Teaching Inquiry: A Guiding Template Fosters Critical Thinking, Barbara D. O'Donnell, Abigail C. Schwent

The Councilor: A National Journal of the Social Studies

This article provides a supportive way to address the marginalization of social studies by teaching inquiry through the use of a template. Inquiry based learning encourages students to make real-world connections by engaging in problem solving and exploration through research. It fosters higher level skills like critical thinking, evaluation, and synthesis of knowledge through experiential learning (Bell, Urhahne, Schanze and Ploetzner 2009). Using inquiry to investigate social studies topics encourages the use of sources from diverse perspectives to understand the complete picture of the event being researched. Teaching social studies through inquiry is a daunting task due to multiple obstacles …

A Deep Dive Into The Nazis’ Animal World: Facilitating The Holocaust Through Symbolization, Filippa V. Frogner

The Downtown Review: An Interdisciplinary Journal Written and Peer-Reviewed by Mandel Honors College Students at Cleveland State University

This paper examines the use of animal symbolism in Nazi propaganda as a tool to dehumanize Jewish individuals and facilitate the Holocaust. Through an analysis of propaganda posters, films, and literature, it highlights how Jews were consistently depicted as animals such as rats, cockroaches, and monkeys—symbols associated with filth, disease, and inferiority. These portrayals, often reinforced by explicit textual messages, stripped Jews of their humanity and encouraged widespread acceptance of their persecution and extermination.

By exploring the methods, extent, and consequences of this dehumanizing propaganda, the paper sheds light on the critical role of animal symbolism in shaping public perception …

Review Of Utopian Genderscapes: Rhetorics Of Women’S Work In The Early Industrial Age, Sarah J. Schuster

Communal Societies

No abstract provided.

Review Of Fourierist Networks Of Reform: The Social Networks Of Nineteenth Century Reformers, Mitchell K. Jones

Communal Societies

No abstract provided.