Digital Commons Network^™

Rethinking The Rise Of Early-Onset Gastrointestinal Cancers: A Call To Action, Benjamin A Weinberg, Caitlin C Murphy, David R Freyer, K Leigh Greathouse, Jan K Blancato, Elena M Stoffel, Julia L Drewes, Anne Blaes, John M Salsman, Y Nancy You, Hannah Arem, Reetu Mukherji, Priyanka Kanth, Xin Hu, Anne Fabrizio, Marion L Hartley, Marios Giannakis, John L Marshall

Faculty, Staff and Student Publications

Since the early 1990s, there has been a dramatic rise in gastrointestinal cancers diagnosed in patients under age 50 for reasons that remain poorly understood. The most significant change has been the increase in incidence rates of early-onset colorectal cancer, especially rates of left-sided colon and rectal cancers. Increases in gastric, pancreatic, and other gastrointestinal cancer diagnoses have further contributed to this trend. We formed a multidisciplinary Think Tank to develop a strategic, coordinated approach to studying early-onset gastrointestinal cancers. This area of research is challenging given multifactorial etiologies. We focused on epidemiology and the environment, the microbiome, and survivorship …

Pathogen And Host Associations Of Soft Ticks Collected In South Texas, Sarah E. Mays Maestas, Lauren P. Maestas, Phillip E. Kaufman

School of Integrative Biological & Chemical Sciences Faculty Publications

Background: Soft ticks (Family: Argasidae) are vectors of relapsing fever Borrelia in the United States and are potential vectors of African swine fever virus, a pathogen that could have a devastating effect on the U.S. swine industry if introduced to the U.S. mainland. Much of the tick-borne disease research in the U.S. focuses on hard ticks, and less is known about the ecology of soft ticks. Some soft tick species found in the southern U.S. have a wide host range and may feed on cattle, swine, native and exotic ungulates, small mammals, reptiles, and humans. Because the feeding habit of …

A Propofol Binding Site In The Voltage Sensor Domain Mediates Inhibition Of Hcn1 Channel Activity, Verena Burtscher, Lei Wang, John Cowgill, Zi-Wei Chen, Christopher Edge, Edward Smith, Yongchang Chang, Lucie Delemotte, Alex S Evers, Baron Chanda

2020-Current year OA Pubs

Hyperpolarization-activated and cyclic nucleotide-gated (HCN) ion channels are members of the cyclic nucleotide-binding family and are crucial for regulating cellular automaticity in many excitable cells. HCN channel activation contributes to pain perception, and propofol, a widely used anesthetic, acts as an analgesic by inhibiting the voltage-dependent activity of HCN channels. However, the molecular determinants of propofol action on HCN channels remain unknown. Here, we use a propofol-analog photoaffinity labeling reagent to identify propofol binding sites in the human HCN1 isoform. Mass spectrometry analyses combined with molecular dynamics simulations show that a binding pocket is formed by extracellularly facing residues in …

Sigma Gamma Epsilon Student Research Poster Session, Geological Society Of America Connects 2024, Anaheim, California, Usa, Scott R. Beason, Lee S. Potter

The Compass: Earth Science Journal of Sigma Gamma Epsilon

The Society of Sigma Gamma Epsilon sponsors a poster session at every annual meeting of the Geological Society of America. The 36th Sigma Gamma Epsilon undergraduate research poster session took place during the 2024 Geological Society of America Annual Meeting (GSA Connects) in Anaheim, California, USA, on Monday, September 23, 2024. Twenty-eight (28) posters were presented in Exhibit Hall D at the Anaheim Convention Center between 8:00 AM and 5:30 PM at the poster session. Titles, authors (italics for the presenting author), affiliations, and abstracts for each poster are listed in this report. Additionally, winners of the Austin A. Sartin …

Fta™ Card Use For Detection Of Mycoplasma Gallisepticum In Wild Birds, Linda Purvis, Dawn E.W. Drumtra

Georgia Journal of Science

Flinders Technology Associates (FTA) cards are increasingly accepted as an accurate method for nucleic acid detection, including testing for the presence of various avian diseases. However, the accuracy of FTA cards for detection of Mycoplasma gallisepticum (MG) in wild birds has not been published. Traditional techniques for testing MG in birds include serum plate agglutanation (SPA), hemagglutination inhibition (HI), polymerase chain reaction (PCR), and enzyme linked immunosorbent assay (ELISA) all of which are time consuming and require significant financial investment into specialized equipment. We tested the efficacy of using FTA cards to detect MG in wild bird carcasses collected in …

Silicon And Phosphorus Co-Doping Of Aluminium Nitride Nanotube (Sip-Alnnt) As Sensors For Polycyclic Aromatic Hydrocarbon Fuel Pollutants: A Computational Approach, Musa Runde, Uzairu Muhammad Sada, Friday O. Izachi, Odey S. Eburu, Anthony M.S. Pembere

Polytechnic Journal

Polycyclic aromatic hydrocarbons (PAHs) have become one of the major pollutants of the environment today due to consistent industrial activities, which have imposed great effects on human health. PAHs are mostly present in high concentrations in soils which are associated with industrial activities and are of concern due to their carcinogenic and toxic effects. With these growing industrial activities, developing alternative methods to mitigate the increasing negative effects caused by PAHs is considered a necessity. The novelty of this study is modelled aluminium nitride nanotube with silicon and phosphorus co-doping (SiP-AlNNT) to study its potential towards the sensing and adsorption …

Synthesis, Identification And Antibacterial Study Of New Ligand Derived From Benzothiazolemethanamine And Its Complexes With Some Metal Ions, Sahar Aqeel Hussain

Maaen Journal for Medical Sciences

A novel substituted 5-chloro-2-benzothiazolemethanamine ligand featuring an imine ‘(-N=CH-) category, 2-((((6-chlorobenzothiazol-2-yl) methyl)imino)methyl)-5-methoxyphenol (CBTMIM), was synthesized through the reaction of 2-benzothiazolemethanamine, 5-chloro, with 2-hydroxy-4-methoxybenzaldehyde in an absolute ethanolic solution. The azomethine ligand and its metal complexes have been identified by using mass spectrometry, ¹H and ¹³C NMR spectroscopy, C, H, N, and S elemental analysis, X-ray diffraction (XRD), (FESEM) microscopy, atomic absorbance spectroscopy. UV-visible spectroscopy, Fourier-transform infrared spectroscopy (FT-IR), magnetic susceptibility, and ionic conductance analysis. The chemical composition and additional measurement data of the metal complexes validate the stoichiometry of the metal: ligand ratio types that include; [M (L)], …

Education Policy Committee Agenda January 2, 2025, Utah State University

Educational Policies Committee

• Approval of Minutes
• Subcommittee Reports
• Other Business
• Adjourn: 4:00pm

Fyn Regulates Aqueous Humor Outflow And Iop Through The Phosphorylation Of Ve-Cadherin., Krishnakumar Kizhatil, Graham Clark, Daniel K Sunderland, Aakriti Bhandari, Logan J Horbal, Revathi Balasubramanian, Simon W M John

Faculty Research 2025

Schlemm's canal endothelial cells (SECs) serve as the final barrier to aqueous humor (AQH) drainage from the eye. SECs adjust permeability to AQH outflow to modulate intraocular pressure (IOP). The broad identification of IOP-related genes implicates SECs in glaucoma. However, the molecular mechanisms by which SECs sense and respond to pressure changes to regulate fluid permeability and IOP remain largely undefined. We hypothesize that mechano-responsive phosphorylation of the cell adhesion molecule VE-CADHERIN (CDH5) in SECs, by FYN and possibly other SRC family kinases, regulates adherens junction (AJ) permeability to AQH in response to IOP. On experimentally raising IOP in mouse …

Prediction Of Patient Drug Response Via 3d Bioprinted Gastric Cancer Model Utilized Patient-Derived Tissue Laden Tissue-Specific Bioink., Yoo-Mi Choi, Deukchae Na, Goeun Yoon, Jisoo Kim, Seoyeon Min, Hee-Gyeong Yi, Soo-Jeong Cho, Jae Hee Cho, Charles Lee, Jinah Jang

Faculty Research 2025

Despite significant research progress, tumor heterogeneity remains elusive, and its complexity poses a barrier to anticancer drug discovery and cancer treatment. Response to the same drug varies across patients, and the timing of treatment is an important factor in determining prognosis. Therefore, development of patient-specific preclinical models that can predict a patient's drug response within a short period is imperative. In this study, a printed gastric cancer (pGC) model is developed for preclinical chemotherapy using extrusion-based 3D bioprinting technology and tissue-specific bioinks containing patient-derived tumor chunks. The pGC model retained the original tumor characteristics and enabled rapid drug evaluation within …

A Study Of The Dormant Period Of Thaumetopoea Pityocampa (Lepidoptera: Notodontidae) In Bulgaria, Gergana Zaeмdzhikova, Md Habibur Rahman Salman

Turkish Journal of Zoology

The pine processionary moth (PPM), Thaumetopoea pityocampa (Denis et Schiffermuller), is a significant pest affecting conifer forests in the Mediterranean region. This study investigated the diapause mechanisms and survival strategies of PPM in summer and winter feeding populations in Bulgaria. The research was conducted from February to April 2021 at five pine plantation sites known for T. pityocampa activity in southwest Bulgaria. Herein, 1224 specimens were collected across different developmental stages. The sampled populations included those exhibiting typical winter feeding as well as atypical summer feeding. Morphological assessments and monitoring of the development of the individuals were conducted under controlled …

Testing And Optimizing Methodologies For Microplastic Extractions From Owl Pellets, Merve Seyfe, Meli̇ke Seyfe, Tolga Kankiliç, Ülkü Ni̇han Tavşanoğlu

Turkish Journal of Zoology

Microplastic pollution is a pressing global environmental concern, potentially threatening ecosystems and entering the food chain. Owls, as nocturnal carnivorous birds, are at significant risk of ingesting microplastics due to their diverse foraging habits. This study aimed to identify the most suitable procedure for extracting microplastics from owl pellets, focusing on efficiency, functionality, and cost and ensuring the extraction of both prey and microplastics without damage. Experiments were conducted on pellets from long-eared owl (Asio otus) collected from three different habitats in Ankara, Türkiye. The extraction of microplastics was then tested using various treatments (n = 25), involving different durations, …

The Correlation Of Anti-Mullerian Hormone (Amh) Level With Anthropometric Measurements In Premenopausal Women, Rana Hammadi, Mohanned Bakir, Gumar Zamil

Iraqi Postgraduate Medical Journal

Background :Anti-Müllerian hormone (AMH) can serve as a good biomarker for the ovarian reserve that can predict female fertility, studying the biological factors that impact AMH levels is necessary for predicting reproductive health outcomes . Obesity (general obesity by body mass index and central obesity by waist circumference), is associated with negative reproductive outcomes that could be related to its impact on AMH level . Female fecundity begins to decrease after women reach the age of 30 years for multifactorial causes that could be hormonal changes .Objective : The study aims to find the association of Anti-mullerian hormone (AMH) level …

Curriculum Subcommittee Agenda January 02, 2025, Utah State University

Educational Policies Committee

• Approval of Minutes
• Program Proposals
• Semester Course Approval Reviews
• Other Business
• Adjourn

Pivotal Roles Of Biglycan And Decorin In Regulating Bone Mass, Water Retention, And Bone Toughness, Rui Hua, Yan Han, Qingwen Ni, Roberto J. Fajardo, Renato V. Iozzo, Rafay Ahmed, Jeffry S. Nyman, Xiaodu Wang, Jean X. Jiang

Department of Pathology, Anatomy, and Cell Biology Faculty Papers

Proteoglycans, key components of non-collagenous proteins in the bone matrix, attract water through their negatively charged glycosaminoglycan chains. Among these proteoglycans, biglycan (Bgn) and decorin (Dcn) are major subtypes, yet their distinct roles in bone remain largely elusive. In this study, we utilized single knockout (KO) mouse models and successfully generated double KO (dKO) models despite challenges with low yield. Bgn deficiency, but not Dcn deficiency, decreased trabecular bone mass, with more pronounced bone loss in dKO mice. Low-field nuclear magnetic resonance measurements showed a marked decrease in bound water among all KO groups, especially in Bgn KO and dKO …

The Effects Of Active Substances Of Clinically Important Drugs On The Survival, Development, And Some Adult Traits Of Drosophila Melanogaster Meigen (Diptera: Drosophilidae), Gökçe Üstündağ, Kemal Büyükgüzel, Ender Büyükgüzel

Turkish Journal of Zoology

Drosophila melanogaster Meigen (Diptera: Drosophilidae) was used as a model organism and fed on an artificial diet with different clinically important drugs under laboratory conditions. The effects of fluconazole, acyclovir, and piperazine on the survivorship, development, adult longevity, fecundity, and hatching rate of the insect were investigated. The results showed that the highest concentration of fluconazole (1250 mg/L) significantly decreased both the rate of larvae reaching the 3rd instar and the rate of pupation from 93.00 ± 2.95% to 11.00 ± 2.59% (χ2 = 134.696; df = 1; p = 0.0001). The highest concentration of acyclovir (200 mg/L) significantly reduced …

Enhanced Motivated Behavior Mediated By Pharmacological Targeting Of The Fgf14/Nav16 Complex In Nucleus Accumbens Neurons, Nolan M Dvorak, Paul A Wadsworth, Guillermo Aquino-Miranda, Pingyuan Wang, Douglas S Engelke, Jingheng Zhou, Nghi Nguyen, Aditya K Singh, Giuseppe Aceto, Zahra Haghighijoo, Isabella I Smith, Nana Goode, Mingxiang Zhou, Yosef Avchalumov, Evan P Troendle, Cynthia M Tapia, Haiying Chen, Reid T Powell, Timothy J Baumgartner, Jully Singh, Leandra Koff, Jessica Di Re, Ann E Wadsworth, Mate Marosi, Marc R Azar, Kristina Elias, Paul Lehmann, Yorkiris M Mármol Contreras, Poonam Shah, Hector Gutierrez, Thomas A Green, Martin B Ulmschneider, Marcello D'Ascenzo, Clifford Stephan, Guohong Cui, Fabricio H Do Monte, Jia Zhou, Fernanda Laezza

Faculty, Staff and Student Publications

Protein/protein interactions (PPI) play crucial roles in neuronal functions. Yet, their potential as drug targets for brain disorders remains underexplored. The fibroblast growth factor 14 (FGF14)/voltage-gated Na+ channel 1.6 (Nav1.6) complex regulates excitability of medium spiny neurons (MSN) of the nucleus accumbens (NAc), a central hub of reward circuitry that controls motivated behaviors. Here, we identified compound 1028 (IUPAC: ethyl 3-(2-(3-(hydroxymethyl)-1H-indol-1-yl)acetamido)benzoate), a brain-permeable small molecule that targets FGF14R117, a critical residue located within a druggable pocket at the FGF14/Nav1.6 PPI interface. We found that 1028 modulates FGF14/Nav1.6 complex assembly and depolarizes the voltage-dependence of Nav1.6 channel inactivation with …

Nucleus-Translocated Gclm Promotes Chemoresistance In Colorectal Cancer Through A Moonlighting Function, Jin-Fei Lin, Ze-Xian Liu, Dong-Liang Chen, Ren-Ze Huang, Fen Cao, Kai Yu, Ting Li, Hai-Yu Mo, Hui Sheng, Zhi-Bing Liang, Kun Liao, Yi Han, Shan-Shan Li, Zhao-Lei Zeng, Song Gao, Huai-Qiang Ju, Rui-Hua Xu

Faculty, Staff and Student Publications

Metabolic enzymes perform moonlighting functions during tumor progression, including the modulation of chemoresistance. However, the underlying mechanisms of these functions remain elusive. Here, utilizing a metabolic clustered regularly interspaced short palindromic repeats (CRISPR)-Cas9 knockout library screen, we observe that the loss of glutamate-cysteine ligase modifier subunit (GCLM), a rate-limiting enzyme in glutathione biosynthesis, noticeably increases the sensitivity of colorectal cancer (CRC) cells to platinum-based chemotherapy. Mechanistically, we unveil a noncanonical mechanism through which nuclear GCLM competitively interacts with NF-kappa-B (NF-κB)-repressing factor (NKRF), to promote NF-κB activity and facilitate chemoresistance. In response to platinum drug treatment, GCLM is phosphorylated by P38 …

Differentiation Of Mullus Barbatus And Mullus Surmuletus (Perciformes, Mullidae) From Turkish Waters Of The Mediterranean Sea Using Otolith Shape Analyses, Semra Saygin

Turkish Journal of Zoology

Red mullet (Mullus barbatus) and surmullet (Mullus surmuletus) are valuable components of the commercial fishery industry in the Mediterranean Sea in Türkiye. To date, morphological and genetic characteristics have been used to distinguish these species. This study aimed to determine whether it was possible to distinguish between the two species using the morphometric features of their sagittal otoliths. Sagittal otoliths were subjected to elliptic Fourier analysis, wavelet analysis, and analysis of otolith shape indices for 117 specimens from the Mediterranean Sea coast of Türkiye (Mullus barbatus: 53 individuals; Mullus surmuletus: 64 individuals). Overall, canonical discriminant analysis (CDA) demonstrated strong discrimination …

Cover And Contents

Turkish Journal of Zoology

No abstract provided.

Atrx Silences Cartpt Expression In Osteoblastic Cells During Skeletal Development, Yi-Ting Chen, Ming-Ming Jiang, Carolina Leynes, Mary Adeyeye, Camilla F Majano, Barakat Ibrahim, Urszula Polak, George Hung, Zixue Jin, Denise G Lanza, Lan Liao, Brian Dawson, Yuqing Chen-Evenson, Oscar E Ruiz, Richard J Gibbons, Jason D Heaney, Yangjin Bae, Brendan Lee

Faculty, Staff and Students Publications

ATP-dependent chromatin remodeling protein ATRX is an essential regulator involved in maintenance of DNA structure and chromatin state and regulation of gene expression during development. ATRX was originally identified as the monogenic cause of X-linked α-thalassemia mental retardation (ATR-X) syndrome. Affected individuals display a variety of developmental abnormalities and skeletal deformities. Studies from others investigated the role of ATRX in skeletal development by tissue-specific Atrx knockout. However, the impact of ATRX during early skeletal development has not been examined. Using preosteoblast-specific Atrx conditional knockout mice, we observed increased trabecular bone mass and decreased osteoclast number in bone. In vitro coculture …

Differential Microbial Community Assembly Following Co-Housing Versus Microbiota Transplant, James S Weagley, Luis Alberto Chica Cárdenas, Ana Romani, Meagan E Sullender, Somya Aggarwal, Heyde Makimaa, Michael P Hogarty, Rachel Rodgers, Elizabeth A Kennedy, Lynne Foster, Lawrence A Schriefer, Megan T Baldridge

2020-Current year OA Pubs

Mouse models are vital tools for discerning the relative contributions of host and microbial genetics to disease, often requiring the transfer of microbiota between different mouse strains. Transfer methods include antibiotic treatment of recipients and colonization using either co-housing with donors or the transplantation of faecal or caecal donor material. However, the efficiency and dynamics of these methods in reconstituting recipients with donor microbes is not well understood. We thus directly compared co-housing, faecal transplantation, and caecal transplantation methods. Donor mice from Taconic Biosciences, possessing distinct microbial communities, served as the microbial source for recipient mice from Jackson Laboratories, which …

N-Linked Fucosylated Glycans Are Biomarkers For Prostate Cancer With A Neuroendocrine And Metastatic Phenotype, Joseph E Ippolito, Hani Nakhoul, Cody Weimholt, Elena Nunez, Nikolaos A Trikalinos, Et Al.

2020-Current year OA Pubs

Prostate cancer is a heterogeneous disease with a spectrum of pathology and outcomes ranging from indolent to lethal. Although there have been recent advancements in prognostic tissue biomarkers, limitations still exist. We leveraged matrix-assisted laser desorption/ionization imaging of formalin-fixed, paraffin embedded prostate cancer specimens to determine if N-linked glycans expressed in the extracellular matrix of lethal neuroendocrine prostate cancer were also expressed in conventional prostate adenocarcinomas that were associated with poor outcomes. We found that N-glycan fucosylation was abundant in neuroendocrine prostate cancer as well as adenocarcinomas at the time of prostatectomy that eventually developed recurrent metastatic disease. Analysis of …

Two-Hit Mouse Model Of Heart Failure With Preserved Ejection Fraction Combining Diet-Induced Obesity And Renin-Mediated Hypertension, Justin H Berger, Xian Chen, Attila Kovacs, Et Al.

2020-Current year OA Pubs

Heart failure with preserved ejection fraction (HFpEF) is increasingly common but its pathogenesis is poorly understood. The ability to assess genetic and pharmacologic interventions is hampered by the lack of robust preclinical mouse models of HFpEF. We developed a novel "two-hit" model, which combines obesity and insulin resistance with chronic pressure overload to recapitulate clinical features of HFpEF. C57Bl6/NJ mice fed a high-fat diet (HFD) for > 10 weeks were administered an AAV8-driven vector resulting in constitutive overexpression of mouse Renin1d. HFD-Renin (aka "HFpEF") mice demonstrated obesity and insulin resistance, moderate left ventricular hypertrophy, preserved systolic function, and diastolic dysfunction indicated …

T Helper 2 Cell-Directed Immunotherapy Eliminates Precancerous Skin Lesions, Tomonori Oka, Neel S. Raval, Mary Tabacchi, Lynn A. Cornelius, Et Al.

2020-Current year OA Pubs

The continuous rise in skin cancer incidence highlights an imperative for improved skin cancer prevention. Topical calcipotriol-plus-5-fluorouracil (calcipotriol-plus-5-FU) immunotherapy effectively eliminates precancerous skin lesions and prevents squamous cell carcinoma (SCC) in patients. However, its mechanism of action remains unclear. Herein, we demonstrate that calcipotriol-plus-5-FU immunotherapy induces T helper type 2 (Th2) immunity, eliminating premalignant keratinocytes in humans. CD4+ Th2 cells were required and were sufficient downstream of thymic stromal lymphopoietin cytokine induction by calcipotriol to suppress skin cancer development. Th2-associated cytokines induced IL-24 expression in cancer cells, resulting in toxic autophagy and anoikis followed by apoptosis. Calcipotriol-plus-5-FU immunotherapy was dependent …

Spatiotemporal Variation Of Vegetation Cover In Mining Areas Of Ysr Kadapa District, Andhra Pradesh Using Remote Sensing And Gis, Vinod Kumar Yarlanki, Prudhvi Raj Muppala, Prem Kumar Yasam, Balaji Gollapudi, Sumanth Moddu, Appanna Besta

Journal of Sustainable Mining

The spatiotemporal variation of vegetation cover in the mining areas of YSR Kadapa district, Andhra Pradesh, using Remote Sensing and GIS techniques. By focusing on the years 2014, 2018, and 2023, the analysis provides insights into changes observed in water bodies, bare soil, sparse vegetation, moderate vegetation, and dense vegetation. The results reveal dynamic trends in land cover categories, highlighting the environmental impact of mining activities in the region. A significant decline in water bodies is observed, with the area reducing from 3.48 km² in 2014 to 1.91km² in 2023. This decrease raises concerns about the potential degradation …

Ensnared By Custom: Mary Astell And The American Bar Association On Female Autonomy, Judy Cornett

Book Chapters

Rhetoric—the arts of practical discourse that we broadly define as the use of symbols to influence belief and action—has something to say about contemporary legal theory and practice. Law and rhetoric in the West were born together nearly 2500 years ago in the Mediterranean. American law has eschewed its rhetorical roots since the late nineteenth century. Denying law’s rhetorical nature helps to construct an impartial façade, shoring up law’s legitimacy. Admitting the rhetorical nature of law would be to admit its partiality, or the point of view inevitably inscribed with every textual choice. At the same time, rhetorical theorists have …

Lessons In Low-Tech: A Handbook For Sustainable Education, Ceri Almrott, Loann Astorino, Sébastien Bette, Benoit Delinchant, Philippe Fortemps, Ulysse Girard, Paul Hendrick, Sacha Hodencq, Fabian Lecron, Julie Lhuissier, Kévin Loesle, Luis Miguel Lopez Santiago, Santiago Perez Rodriguez, Gauthier Renard, Tatiana Reyes, Virginie Vandenbulcke, John Walsh

Other resources

LT4SUSTAIN, an Erasmus+ funded transnational project, is at the forefront of responding to the increasing awareness of environmental and climate challenges. This awareness, particularly among youth, has led to a demand for social justice. With the coordinated work among six institutions, ranging from higher education institutions to private companies and associations, LT4SUSTAIN aims to raise awareness of Lowtech across society.

LT4SUSTAIN is pioneering a unique approach to technology design. By developing “hackathons” and other “hands-on” events, we are engaging students and industry in a way that improves inclusiveness. Our objective is to equip individuals with the skills to embark on …

Lusaka's Colonial Legacy: Town Planning, Public Health, And The Making Of A Segregated City, 1913–1963. A Study Of Power, Inequality, And Urban Development, Wamburakwao J. Sapao

Zambia Social Science Journal

This paper explores the intersection of town planning and public health policy in Lusaka, Northern Rhodesia (now Zambia), during the colonial period (1913–1963), which was a time of significant urban growth and transformation. British colonial authorities adapted Ebenezer Howard's Garden City principles to design and manage Lusaka, but these measures perpetuated spatial control, segregation, and social engineering, thus exacerbating racial and socio-economic disparities. By analysing secondary and primary sources, including planning ordinances, zoning regulations, and public health policies, this study reveals how these measures shaped the city's development and reinforced inequalities. Despite colonial intentions for a white settler-city, Lusaka evolved …

How Assistance Dogs Impact The Academic And Social/Emotional Development Of Students With Disabilities, Elizabeth A. Bloom

All Electronic Theses and Dissertations

This literature review explores the impact of using assistance dogs in special education to address social-emotional development and academic success for students with various disabilities. The review evaluated dog-assisted interventions, a form of animal-assisted therapy, increasingly used in schools, libraries, hospitals, and higher education settings. The research findings reported positive outcomes when animals were used, such as increased motivation, reduced anxiety, and improved reading skills (Bassette and Taber- Doughty (2013), Goodmon et al. (2021), Herderson et al. (2020). More rigorous, long-term research across diverse student populations and disability categories is needed to address the long-term benefits of animal- assisted therapy. …