Digital Commons Network^™

Cryptosporidium Virus Integration Into The Host Cells, Alyssa Genaro

Biochemistry and Molecular Biology

Cryptosporidiosis is a disease that affects a large amount of people and having a high mortality rate for those that are immunocompromised such as the elderly and infants. The disease is linked to a parasite called Cryptosporidium parvum, which is mostly known to infect cattle and other mammals such as mice and humans. The parasite contains a double stranded RNA virus, the Cryspovirus (CSpV1) that has a non-enveloped icosahedral capsid, with a T=2* icosahedral symmetry. Little is known is known about the contribution of CSpV1 to the disease; In this study we show that infection of an immunocompromised mouse model …

Exogenous Nicotinamide Protects Mycobacterium Bovis Bcg From Gsh-Induced Reductive Stress By Enhancing Nad+ Synthesis, Tamia Cline

Biochemistry and Molecular Biology

No abstract provided.

Prioritization Of Research On Drought Assessment In A Changing Climate, Joel Lisonbee, Britt Parker, Erica Fleischman, Trent W. Ford, Kyle R. Bocinsky, Gretel Follingstad, Abby Frazier, Zachary H. Hoylman, Amy R. Hudson, John W. Nielsen-Gammon, Natalie A. Umphlett, Elliot Wickham, Aparna Bamzai-Dodson, Royce Fontenot, Brian Fuchs, John Hammond, Jeffrey E. Herrick, Mike Hobbins, Andrew Hoell, Jacob Jones, Erin Lane, Zachary Leasor, Yongqiang Liu, Jason A. Otkin, Dennis Todey, Roger Pulwarty

Geography

Drought is a period of abnormally dry weather that leads to hydrological imbalance. Drought assessments determine the characteristics, severity, and impacts of a drought. Climate change adds conceptual and quantitative challenges to traditional drought assessments. This paper highlights the challenges of assessing drought in a climate made non-stationary by human activities or natural variability. To address these challenges, we then identify 10 key research priorities for advancing drought science and improving assessments in a changing climate. The priorities focus on improving drought indicators to account for non-stationarity, evaluating drought impacts and their trends, addressing regional differences in non-stationarity, determining the …

Impact Of Polysaccharides On Advancing Plant-Based Meat Alternatives, Prashant Dahal, Clifford Hall, Srinivas Janaswamy

Dairy Science and Food Science Faculty Publications: 2022 to Present

Plant-based meat products are a valued choice for vegetarians and others. Their production has been perceived as an innovation promoting animal welfare and sustainability. However, there are challenges in simulating desirable appearance, texture, and flavor using only plant-based protein sources. Polysaccharide addition during the formulation and texturization of plant proteins can improve the physi- cochemical and sensory properties of texturized protein products. In this regard, a clear understanding of the fundamental properties of polysaccharides is essential for transforming plant proteins into fibers or nonfilamentous protein aggregates. Enhancing water-holding capacity, gelation, and binding functionality is crucial for overcoming structural and textural …

The Nebraska Bird Review (March 2025) 93(1), Whole Issue

Nebraska Bird Review

Winter Field Report, December 2024–February 2025, by W. Ross Silcock
2024–2025 Christmas Bird Counts, by Don Paseka
Annual Color Photo Section
Annual Treasurer’s Report for 2024, by Jan Johnson
Subscription and Organization Information

A Snitch In Time Can Help Deport Nine: Proposing A Private Enforcement Scheme To Spur Self-Deportations, Ajay Gupta

The Business, Entrepreneurship & Tax Law Review

Any forcible deportation drive that the incoming Trump administration may undertake to remove some of the many millions of aliens illegally present in the country would be limited in scope, underscoring the importance of goading self-deportations for perceptibly reducing these aliens’ numbers by curtailing their employment opportunities. Based in part on Britain’s experience with eradicating child labor in the nineteenth century, the article proposes a scheme of private enforcement for rendering unemployable a large proportion of unauthorized aliens in the United States labor market today. The proposal comprises enacting a punitive tax on all compensation paid for the personal services …

Annual Color Photo Section

Nebraska Bird Review

The following seven pages show examples of this year’s theme: birds feeding or carrying food.

Osprey with striped bass
Spotted Sandpiper with beetle
Scissor-tailed Flycatcher with insect
Male Pine Grosbeak with green ash seeds
Merlin eating sparrow
Whooping Crane carrying ear of corn
Yellow-billed Cuckoo with harvestman spider
Black-billed Magpie eating grain
Red-tailed Hawk with plains garter snake
Summer Tanager with hackberry emperor butterfly
Cattle Egret with bullfrog
Juvenile Red-shouldered Hawk eating garter snake
Red-breasted Merganser eating fish
Juvenile White Ibis eating unidentified item
Bohemian Waxwing eating crab apples
Rose-breasted Grosbeak eating sunflower seeds
Loggerhead Shrike eating dragonfly
Yellow-crowned Night …

2024–2025 Christmas Bird Counts, Don Paseka

Nebraska Bird Review

For the second year in a row, all twenty CBCs [Christmas Bird Counts] were run during the 2024–2025 season. The weather was generally cooperative, although five circles reported fog and two others had rain. Branched Oak-Seward was postponed a week due to icy conditions on the originally scheduled day. The average high temperature for all circles on count day was 41 and the average low temperature was 22. Because December had remained relatively mild, there was a good deal of open water, which encouraged many species of water birds to remain. Consequently, most of the circles reported species totals higher …

Winter Field Report, December 2024–February 2025, W. Ross Silcock

Nebraska Bird Review

Since I started a few years ago to compare each season’s reports with the status of each species as presented in BONO (Species Accounts – Birds of Nebraska – Online), I had expected that “Routine reports” would apply to an increasing number of species as the BONO database firmed up, but this hasn’t happened. My comments from last winter continue to be valid this winter, now for the third winter in a row: As was the case for winter 2022–2023, the big general story was the large number of reports of tardy fall migrants and unexpectedly northerly occurrences in mid-winter… …

Principles For The Design Of Visual Progress Bars To Improve Motivation In Online Learning, Tania Shotts Williams

Masters Theses & Doctoral Dissertations

Progress bars are used in many user interfaces to indicate user progress or wait time. Their main role is to set user expectations, and they can be auditory or visual. The use of visual progress bars is found in many applications, including games and is accepted as a strategy for gamifying user experiences. However, little research exists regarding the design of this tool, especially in how to leverage design elements to impact motivational affordance. Since progress bars are an element to gamify user interfaces, it benefits researchers and designers to have a deeper understanding of how to design the tool …

The Combined Treatment Of Chinese Herbal Medicines Is Correlated With A Lower Risk Of Rheumatoid Arthritis In Patients With Depression: Evidence From A Population-Based Patient–Control Study, Chieh-Tsung Yen, Hanoch Livneh, Hui-Ju Huang, Ming-Chi Lu, Ming-Chi Lu, Wei-Jen Chen, Tzung-Yi Tsai

Counselor Education Faculty Publications and Presentations

Background: Major depression places psychological strain on the individual that may increase the risk of developing rheumatoid arthritis (RA). Though the use of Chinese herbal medicines (CHMs) is widespread in clinical practice, its effect on the prevention of RA incidents is still unknown. This study aimed to evaluate the association between CHMs use by patients with depression and their subsequent risk of being diagnosed with RA.

Une Library Services Quarterly Report March 2025, Une Library Services

Quarterly Reports

Highlights of accomplishments of the University of New England's Library Services department.

Alfred Russel Wallace Notes 35. Natural Selection By Evolution., Charles H. Smith

Faculty/Staff Personal Papers

Alfred Russel Wallace (1823?1913) is remembered, with Charles Darwin, as the co-originator of the concept of evolution by natural selection. But Wallace’s framing of the idea increasingly became one in which natural selection itself was regarded as a law of nature, not a theory per se.

Ml-Urinequant: A Machine Learning Program For Identifying And Quantifying Mouse Urine On Absorbent Paper., Warren G Hill, Bryce Maciver, Gary Churchill, Mariana G Deoliveira, Mark L Zeidel, Marcelo Cicconet

Faculty Research 2025

The void spot assay has gained popularity as a way of assessing functional bladder voiding parameters in mice, but analyzing the size and distribution of urine spot patterns on filter paper with software remains problematic due to inter-laboratory differences in image contrast and resolution quality and non-void artifacts. We have developed a machine learning algorithm based on Region-based Convolutional Neural Networks (Mask-RCNN) that was trained in object recognition to detect and quantitate urine spots across a broad range of sizes-ML-UrineQuant. The model proved extremely accurate at identifying urine spots in a wide variety of illumination and contrast settings. The overwhelming …

Melanocortin 4 Receptor-Dependent Mechanism Of Acth In Preventing Anxiety-Like Behaviors And Normalizing Astrocyte Proteins After Early Life Seizures., Mohamed R Khalife, Colin Villarin, Juan Manuel Ruiz, Sam A Mcclelland, Khalil Abed Rabbo, J Matthew Mahoney, Rod C Scott, Amanda E Hernan

Faculty Research 2025

Epilepsy, affecting millions globally, often leads to significant cognitive and psychiatric comorbidities, particularly in children. Anxiety and depression are particularly prevalent, with roughly a quarter of pediatric epilepsy patients having a comorbid diagnosis. Current treatments inadequately address these issues. Adrenocorticotropic hormone (ACTH), a melanocortin peptide, has shown promise in mitigating deficits after early-life seizures (ELS), potentially through mechanisms beyond its canonical action on the melanocortin 2 receptor. This study explores the hypothesis that recurrent ELS is associated with long-term anxiety and that treatment with ACTH can prevent this anxiety through a mechanism that involves the melanocortin 4 receptor (MC4R) in …

A Preliminary Report Of The Carotenoid Assessment In Adults 50 Years Of Age And Older In Louisiana, Mary-Catherine Feazell

Master's Theses

Fruits and vegetables are at the core of a healthy, balanced diet. They assist in preventing the development of chronic diseases such as hypertension, diabetes, cardiovascular disease, and cancer (Fadnes, et al., 2022). Aging is a natural biological process followed by disease, cognitive impairment, and a natural decline of the body’s ability to perform at its best. The older adult population is currently the fastest-growing population globally (El-Shebiney et al., 2022). Vitamin A is crucial for several parts of the body to function correctly. Despite the positive effects of Vitamin A on the body, the recommended dietary intake is not …

Maine Career Exploration: Final Evaluation Report, Julia Bergeron-Smith Mppm, Msw, Sarah Goan, Madison Burke, Becky Wurwarg, Amy Geren, Shannon Saxby

Publications

The Maine Career Exploration (MCE) Program was a two-year, $25 million pilot initiative launched in 2022 by Governor Janet Mills as part of the Maine Jobs and Recovery Plan. The program aimed to connect young people aged 16 to 24 with Maine’s economy through paid, age-appropriate career experiences that matched their interests, while also expanding career exploration opportunities in schools and communities and building long-term infrastructure to sustain these efforts. Managed by the Maine Department of Economic and Community Development, MCE distributed funding across three main streams: the Maine Children’s Cabinet Career Exploration Pilot Project, the Maine Department of Education’s …

2025 Little International Agricultural Exposition Catalog, Little International Agricultural Exposition South Dakota State University

Little International "Little I" Agricultural Exposition Catalogs

This is the catalog for the 102nd Little International 'Little I' Agricultural Exposition, held on March 28 & 29, 2025.

Self-Mustering Yards For Pastoral Livestock Management, Department Of Primary Industries And Regional Development, Western Australia

Animal production and livestock factsheets

Self-mustering yards (SMYs) are an important component of effective total grazing management in the pastoral regions. These yards are used to self-muster cattle, sheep and goats, as well as native browsers and feral animals as they enter the yards to access the water point.

Ecology Of Ixodes Scapularis Say: Experimental And Observational Studies With Social Perspectives On Ticks And Tick-Borne Diseases, Kaitlin M. Mcdonald

Dartmouth College Ph.D Dissertations

Tick-borne diseases are a growing concern globally. Understanding the factors that influence tick ecology and people’s understanding of that ecology is crucial for developing effective tick management and disease prevention strategies. In this work, I investigated fundamental questions about the ecology of a primary vector of medically important pathogens in the United States, the blacklegged tick Ixodes scapularis Say, and identified common misconceptions about ticks and tick-borne diseases on social media. First, I examined the effects of temperature and moisture stress on the movement of adult female I. scapularis in laboratory experiments. Using a Drosophila Activity Monitor, ticks were exposed …

Research Newsletter Faculty Of Arts & Sciences: Issue Iii, Faculty Of Arts And Sciences

Faculty of Arts and Sciences Archives

• Cutting-edge research
• Academic engagement
• Interdisciplinary research
• Public health
• Water-related conflicts
• Salinity tolerance
• Seed priming
• Thatta
• Phonology workshop
• Creative talks

Brain-Type Natriuretic Peptide Is A Useful Biomarker Of Cardiovascular Disease And Predictor Of Cardiac-Related Mortality In Chimpanzees (Pan Troglodytes), Angela M. Achorn, Carolyn L. Hodo, Martha E. Hensel, Elizabeth R. Magden, Stephanie J. Buchl

Anthropology Faculty Publications

OBJECTIVE

To validate the use of brain-type natriuretic peptide (BNP) for detecting and monitoring cardiac dysfunction in captive chimpanzees (Pan troglodytes).

METHODS

We analyzed cross-sectional (N = 175) and longitudinal (N = 76) BNP, echocardiogram, ECG, and pathology data from living and deceased captive chimpanzees to examine age and sex effects and to assess the usefulness of BNP for detecting cardiovascular disease and predicting mortality. The study period was from July 2010 through October 2024.

RESULTS

Brain-type natriuretic peptide values were significantly associated with age, and males exhibited significantly higher BNP values than females. Brain-type natriuretic peptide values …

The Anchor: March 2025, Issue Three, Hope College

The Anchor: 2025

The Anchor began in 1887 and was first issued weekly in 1914. Covering national and campus news alike, Hope College’s student-run newspaper has grown over the years to encompass over two-dozen editors, reporters, and staff. For much of The Anchor's history, the latest issue was distributed across campus each Wednesday throughout the academic school year (with few exceptions). In recent years The Anchor moved to monthly print issues and a more frequently updated website. The Anchor is now published in print twice per academic semester. Occasionally, the volume and/or issue numbering is irregular.

Asking The Rights Questions: An Emgerency Action Exception To The Major Questions Doctrine, Mark Hager

Minnesota Law Review Vols. 106:2 onward (2021-present)

Congress delegates broad discretionary power to administrative agencies to respond to emergency situations, taking advantage of their extraordinary expertise and response speed. Yet these delegations are defined by a judicial rule known as the “Major Questions Doctrine.” The Major Questions Doctrine seeks to protect the separation of powers by preventing excessive use of executive power without clear delegation by Congress. Where a “major question” of vast economic or political significance is raised, it requires “clear” authorization in the delegating statute. During COVID-19, the Supreme Court used the doctrine to strike down several response programs, including: the Center for Disease Control’s …

Commercial Development Utilizing Faith And Business Innovation, Sandra Moon

Doctor of Ministry Projects and Theses

In the evolving landscape of business and commerce, the intersection of faith and business innovation has become a topic of debate, particularly in a world that increasingly values efficiency, scalability, and profit. This dissertation examines the role of spirituality in business leadership. We will explore how Christian values, servant leadership, and heart-mind coherence contribute to a more sustainable, ethical, and community-driven business model. Through the lens of my family’s business, Sam Moon Group, I will explore how faith-based leadership can coexist with success and serve as its very foundation. The early journey of Sam Moon Trading Company, from a small …

Efficacy Of Immersive Virtual Reality Gameplay In Environmental Attitude Change: The Case Of Abandoned Offshore Oil Platforms In Santa Barbara, Arun Prasad Srinivasan Manoharan

Master's Theses

Public perception plays an important role in shaping conservation policies and decisions, especially in contested environmental spaces. Offshore oil platforms, historically viewed as environmental hazards, have been found to serve as marine habitats that support diverse marine life. However, public perception remains largely negative, influenced by concerns over pollution from past oil spill accidents. Traditional environmental education methods, such as lectures and documentaries, often fail to engage audiences effectively or shift entrenched opinions. This study explores the efficacy of immersive Virtual Reality (VR) gameplay in changing environmental attitudes, specifically in the context of abandoned offshore oil platforms in Santa Barbara, …

Insulin Clearance At Randomisation And In Response To Treatment In Youth With Type 2 Diabetes: A Secondary Analysis Of The Today Randomised Clinical Trial, Kristen J Nadeau, Silva A Arslanian, Fida Bacha, Sonia Caprio, Lily C Chao, Ryan Farrell, Kara S Hughan, Maria Rayas, Melinda Tung, Kaitlyn Cross, Laure El Ghormli

Children’s Nutrition Research Center Staff Publications

Aims/hypothesis: Insulin resistance and compensatory hyperinsulinaemia are core features leading to beta cell failure in youth-onset type 2 diabetes. Insulin clearance (IC) is also a key regulator of insulin concentrations, but few data exist on IC in youth-onset type 2 diabetes. In a secondary analysis of our Treatment Options for Type 2 Diabetes in Adolescents and Youth (TODAY) randomised clinical trial, we investigated potential sex-, race-, ethnicity- and treatment-related differences in IC in youth-onset type 2 diabetes and aimed to identify metabolic phenotypes associated with IC at baseline and in response to metformin, metformin plus a lifestyle intervention, and metformin …

Regionalism And The Federal Reserve Banks, Kathryn Judge, Lev Menand

Faculty Scholarship

Regionalism is central to our country’s central banking system. Rather than rely on a single organization to set monetary policy and oversee banks, Congress created a multiplicity of bodies including twelve Federal Reserve Banks (FRBs), each designed to operate in a different part of the country. These FRBs are an early and undertheorized example of how the federal government uses regional bodies to formulate and administer federal policy. When they were first authorized in 1913, their regional character assuaged concerns about centralizing power over the economy. Today, the FRBs continue to play a number of important roles, helping to shape …

078-S2-L2-127.003, Morehead State University History Department (Morehead, Ky)

Defending Savannah: History and Archaeology of the Gibson's Point Battery

Femur bone from a small animal - excavated between March 17-19, 2025

Among-Population Variation In Telomere Regulatory Proteins And Their Potential Role As Hidden Drivers Of Intraspecific Variation In Life History, Sarah E. Wolf, Mary J. Woodruff, David A. Chang Van Oordt, Ethan D. Clotfelter, Daniel A. Cristol, Elizabeth P. Derryberry, Stephen M. Ferguson, Mark T. Stanback, Conor C. Taff, Maren N. Vitousek, David F. Westneat, Kimberly A. Rosvall

Biology Faculty Publications

Biologists aim to explain patterns of growth, reproduction and ageing that characterize life histories, yet we are just beginning to understand the proximate mechanisms that generate this diversity. Existing research in this area has focused on telomeres but has generally overlooked the telomere's most direct mediator, the shelterin protein complex. Shelterin proteins physically interact with the telomere to shape its shortening and repair. They also regulate metabolism and immune function, suggesting a potential role in life history variation in the wild. However, research on shelterin proteins is uncommon outside of biomolecular work. Intraspecific analyses can play an important role in …