Digital Commons Network^™

From Elementary School To Doctoral Education: An Autoethnographic Journey, Gwendolyn D. Dailey

University of the Pacific Theses and Dissertations

Every child has a right to education, and their skin color should not determine their education quality. However, since the landmark case of Brown v. Board of Education (1954), it has been proven that race continues to matter in the success and failure of education (Delgado & Stefancic, 2001). The persistent achievement gaps between students of different racial and ethnic backgrounds, as well as the disparities in access to high-quality educational opportunities, demonstrate how race and ethnicity shape the educational experiences of students of color (Stanford Center for Education Policy Analysis, 2012). Unfortunately, stories such as Ruby Bridges of New …

The Impact Of Competency-Based Education And Learning Implementation On Technical Colleges Outcomes: Kuwait College For Technological Studies (Cts) Case Study, Mohammad Abdulmohsen Alshaiji

University of the Pacific Theses and Dissertations

Many colleges and training institutions have shifted to Competency-Based Education/Learning (CBE/L) after using the traditional time-credits approach. Students’ achievements and progress are accumulated, not only by credit hours for theoretical knowledge but also, through demonstrating their practical competences.

In CBE/L, students are assessed based on their ability to perform specific tasks using the knowledge and skills (competencies) required for each task in their academic course, regardless of how long such progression might take. The traditional method of learning was time-based on course credits, which last for a specific period of time, and through which students are learning more theoretical knowledge …

Swipe Up And Break Up: A Grounded Theory Study Exploring The Impact Of Tiktok On Adolescents’ Perceptions Of Love And Romantic Relationships, Amitoj Sandhu Kaur

University of the Pacific Theses and Dissertations

Adolescence is a time period when major developments occur with respect to adolescents’ physical, emotional and cognitive capabilities, and such developments ultimately make it a pivotal time for a person’s identity formation and understanding of interpersonal relationships. In today’s world, social media is extremely popular, especially among adolescents, and it has influenced their behaviors, perceptions and interactions with others. With TikTok, a social media platform, gaining popularity in recent years and overwhelmingly so among adolescents, researchers began researching the general impact of TikTok on adolescents’ mental health. Some researchers have begun exploring niche research topics related to the impact of …

Effects Of Glyphosate-Based Herbicide Exposure On Life History, Stress Tolerance, And Microbiome—From Plasticity To Evolution, Jacob R. Whitlock

University of the Pacific Theses and Dissertations

Glyphosate (GLY) is the most used pesticide worldwide, and GLY-based herbicides (GBHs) can affect animals’ microbiomes and, in turn, their physiology and morphology. Environmental stressors can be mitigated by flexibility in life-history strategies, which can also dictate animal physiology and morphology. However, we lack an understanding of how GBH influences life-history strategies and stress tolerance, in addition to its effects across generations. Thus, I exposed the variable field cricket, Gryllus lineaticeps, to GBH within- and across-generations to examine the role of GBH in developmental plasticity and evolution. Specifically, I measured its effects on life-history traits (e.g., developmental duration and a …

Effects Of Fetal Bovine Serum On The Proteome And Secretome Of Pichia Pastoris, Kenneth L. Nguyen

University of the Pacific Theses and Dissertations

Komagataella pastoris, formerly known as Pichia pastoris, and hereafter referred to as Pichia, is a methylotrophic yeast widely employed as a recombinant protein factory for biotechnical and industrial purposes. P. pastoris boasts the ability to thrive at high cell densities, executes numerous post-translational modifications, and exhibits minimal secretion of endogenous proteins, thus greatly facilitating the expression and purification of recombinant proteins. Despite these advantages, Pichia still presents certain challenges as an expression system. Occasionally, recombinant proteins are retained within the cell and subject to degradation. Furthermore, Pichia falls short in matching the production capabilities of more widely used systems like …

The Role Of The Unfolded Protein Response In Fatty Liver Disease, Anusha L. Murshed

University of the Pacific Theses and Dissertations

The unfolded protein response (UPR) is composed of three highly conserved pathways (ATF6, IRE1, PERK). Cellular stressors induce protein misfolding and aggregation in the endoplasmic reticulum (ER). This signaling pathway maintains protein homeostasis when there is stress in the ER. When the UPR is activated, the eukaryotic initiation factor 2 alpha (eIF2α) becomes phosphorylated, which inhibits global mRNA translation. If ER stress remains chronically unmitigated, the UPR induces apoptosis. GADD34 and CReP shift in expression when the UPR is activated and work as phosphatases and dephosphorylate eIF2α in a feedback loop, allowing protein synthesis to resume. Several human diseases, including …

On The Influence Of Private Stimulus Magnitude When Reporting Private Events, Christian T. Hickman

University of the Pacific Theses and Dissertations

The nature of private events provides challenges to developing a scientific understanding of the conditions under which humans learn to describe private events. Replicating and extending procedures from Stocco et al. (2014), we further evaluated the conditions under which verbal responses come under the control of private stimuli. Given that some participants vocal responses came under the control of public stimuli in Stocco et al. (2014), we implemented more subtle public accompaniments with all participants to reduce the likelihood of public stimuli acquiring control of participant’s verbal responses. Further, we systematically manipulated the visual clarity of the presented stimuli using …

Insight Into A Sexually Dimorphic Ostracod Crustacean By Mass Spectrometry And Microtomography, Cindy D. Davis

University of the Pacific Theses and Dissertations

The importance of the central nervous system cannot be understated. An array ofmolecules associated with the brain regulate basic behaviors as well as sex specific behaviors. Describing the molecular background is not the only way that I can learn more of the central nervous system. Describing the anatomy of the central nervous system can be crucial in understanding what regions of the brain is particularly key to the animal. Euphilomedes carcharodonta is a small marine crustacean native to the subtidal zone of the California coast. This ostracod makes for a compelling candidate to explore these research interests as this organism …

Exploring Culture, Support, And Success Among Mexican American Female Students At A Hispanic Serving Institution, Joanna Saldana

University of the Pacific Theses and Dissertations

Educational attainment among Hispanic populations in the United States remains a challenge, particularly among Mexican Americans who exhibit lower rates of degree completion. This dissertation examined the influence of cultural factors, specifically familism and collectivism, on the educational experiences of Mexican American undergraduate women at San Joaquin Delta College (SJDC) in California's San Joaquin Valley. The study aimed to elucidate how levels of familism and collectivism predict social, academic, and psychological support needs, as well as success strategies among this demographic.

Literature highlights the significance of familism, emphasizing familial obligations, and collectivism, prioritizing group harmony, within Mexican American communities. Mexican …

Filipina American Mothers’ Experiences Obtaining Services For Their Children With Autism Spectrum Disorder, Nina Chelle Boling

University of the Pacific Theses and Dissertations

Autism spectrum disorder (ASD) is a multifaceted developmental condition that manifests in early childhood, affecting various aspects of neurologic, biological, adaptive, social, linguistic, and cognitive functions. A timely and accurate diagnosis of ASD is crucial for effective intervention, promoting personal and social growth, and fostering independent adulthood. However, obtaining this diagnosis can pose challenges, particularly for people of color, who often encounter disparities in healthcare access compared to their White counterparts. This study aims to investigate the experiences of Filipina mothers raising children with ASD, specifically focusing on their journey to access appropriate autism services.

As of 2019, there were …

Understanding Latina/O/X Puente Alumni Student Experiences With Sense Of Belonging And Validation, Stephanie Teresa Razo

University of the Pacific Theses and Dissertations

The primary focus of this study was on how the Puente Project helps Latina/o/x community college students feel supported and validated. Additionally, it focused on how community and familial efforts can influence students’ experiences, and how the Puente Project leverages those forms of capital. Examining the lived experiences of Latina/o/x Puente community college alumni contributed to the study of retention and graduation initiatives for Latina/o/x students in the California Community College system. For this study, the participants chosen already completed the Puente program at a California Central Valley community college, transferred to a four-year institution, and either graduated with—or are …

Exploring Latinx Students’ Perceptions And Experiences Of Servingness Through Platica At A Hispanic-Serving Community College, Pedro Reynoso Valdez

University of the Pacific Theses and Dissertations

The main focus of this study centers on the overarching question, What does it mean to serve Latinx students at a Hispanic serving community college (HSCC)? This recurring question, both in research and in practice, has brought critical attention and dialog regarding the concept and practice of servingness; specifically, it has shed light on how Hispanic-serving institutions (HSIs), including HSCCs, conceptualize and enact their respective HSI identity. However, oftentimes, missing from this conversation are the perceptions and experiences of Latinx students themselves enrolled at HSCCs. As a result, there has been a call for more research that incorporates Latinx students’ …

On The Social Validity Of Teaching Children To Give A Polite Response, Nancy V. Ramirez

University of the Pacific Theses and Dissertations

Some children, including individuals diagnosed with autism spectrum disorder (ASD), may respond rudely when expressing their opinions about nonpreferred gifts or aspects of someone else’s appearance (Bergstrom et al., 2016; Saarni, 1984; Talwar et al., 2007; Xu et al., 2010). One proposed solution discussed in the literature to decrease rude responses in children involves teaching children to tell a socially appropriate lie, often referred to as prosocial lies, as an alternative response. These types of lies are defined as “lies that have some benefit for the lie recipient and are not intended to cause harm to another individual” (Popliger et …

Plasticity In Response To Temperature Magnitude And Variation---From Life History To Thermal Tolerance And Coloration, Austin Rex Hoffman

University of the Pacific Theses and Dissertations

Warming associated with climate change has many direct and downstream effects on animals. For example, warmer developmental temperatures can improve heat tolerance and reduce insect melanization, which is related to coloration, thermoregulation, immunity, desiccation resistance, and potentially life-history traits, such as investment into reproduction and dispersal. Increased temperature variation is also a feature of climate change, and it may have a larger impact on animals than warming. However, I lack insight into the combined effects of temperature magnitude and variability on important traits of life history, thermal tolerance, and coloration. Thus, I integrated temperature variation into thermal performance using a …

Development Of Nano Formulations Of Lipophilic Platinum Complexes Against Lung Cancer, Zizhao Xu

University of the Pacific Theses and Dissertations

Lung cancer remains a leading cause of death worldwide and urges the development of more effective and safer treatment options. Conventional platinum-based drugs like cisplatin, while effective, are associated with significant systemic toxicity, particularly nephrotoxicity. Nano formulations, such as liposomal and micellar delivery systems, represent a promising approach to enhance the anticancer activity and reduce the toxicity of platinum complexes.

This study develops and evaluates novel miriplatin-loaded nano formulations for lung cancer therapy. We prepared and screened various liposomal and micellar formulations of miriplatin by either thin-film hydration or co-solvent evaporation, which identified a number of formulations with appropriate sizes …

Transgenerational Effects Of Stress On The Plasma Proteome Of A Marine Mammal, Emily Voelkner

University of the Pacific Theses and Dissertations

The physiological stress response enables animals to respond to changes in their environment, and is mediated by the hypothalamic-pituitary-adrenal (HPA) axis in mammals. Increased activation of the HPA axis by repeated stress during critical life stages like reproduction could affect fitness. Information about a stressor can be communicated to offspring via hormone signals prenatally, or postnatally via milk, and affect offspring development and stress reactivity. Experimentally activating the HPA axis by adrenocorticotropic hormone (ACTH) administration results in the synthesis of the major glucocorticoid hormone cortisol, which has well-studied far-reaching effects on growth, metabolism, and immunity. Beyond cortisol levels alone, biomarkers …

Utilizing Ai Integrated Neuroimaging Technology To Expand Upon Machine Learning In Positron Emission Tomography Technology With The Aim Of Detecting Amyloid Beta Biomarkers Early In The Onset Of Alzheimer's., Ethan S. Terman

UROP Posters

Early intervention in Alzheimer's is vital for treatment. The earlier a professional can detect symptoms and make a diagnosis the earlier a prognosis can be implemented. With the prevalence of data in our day-to-day world combined with Artificial intelligence (AI), utilizing both for machine learning can pave the way for more accurate and efficient detection of Alzheimer's and other neurodegenerative diseases. AI combined with Machine learning (ML) increases diagnostic efficiency and reduces human errors, making it a valuable resource for physicians and clinicians alike. With the increasing amount of data processing and image interpretation required, the ability to use AI …

Lycosidae Abundance And Diversity Across Lawn And Leaf Litter Substrate, Sage O. Lockett, Dan Albrecht-Mallinger

UROP Posters

Significant knowledge gaps exist in how land-cover impacts ground-hunting spider populations. To fill these gaps, this study investigates a common family of ground-hunting spiders, Lycosidae, to determine differences in their abundance and diversity in deciduous leaf litter and managed turfgrass (lawn). The study was conducted within a forested ecosystem at Virginia Commonwealth University's Rice Rivers Center in Charles City County, Virginia. I placed 10 belt transects (1m x 20m) on lawn substrate and 10 identical transects in deciduous forest leaf litter substrate. I performed repeated visual census via eyeshine and manual capture of up to three individuals per transect …

Keep It Simple? Effects Of Color And Age On Product Packaging, Saamiya R. Mohammed, Alex Robinson

UROP Posters

Packaging has always played a pivotal role in consumer decision-making. Specifically, the color of the visual elements placed on product packaging have garnered significant attention for their potential to influence consumer perceptions and behaviors. Color is believed to have emotional/psychological associations across cultural and societal contexts.

On the one hand, research has noted that the use of grayscale does not elicit an emotional response (Clarke and Costall, 2008) and this may be because they’re considered passive colors (Bottomley and Doyle, 2006). Conversely, Jacobs et. al (1991), found that black is associated with being expensive and powerful. Based on the conflicting …

Neurodevelopmental Vulnerability To Gestational Ozone Exposure, Vishnupriya Alavala, Sarah E. Brent, Christopher G. Canal, Joseph Wang, Russell P. Hunter, Matthew J. Campen, Andrew K. Ottens

UROP Posters

Ambient air pollution accounts for about 4.2 million premature deaths annually per the World Health Organization. Ozone (O3) is a highly reactive air pollutant found in smog and is implicated in cellular damage leading to organ dysfunction. Ambient air pollution is associated with neurodevelopmental, behavioral, and cognitive disorders though ozone’s role is unknown. Studies here look at ozone exposure shortly after implantation vs. shortly before term to evaluate differences in neurodevelopmental susceptibility over time.

To inquire on the effects of ozone on the fetal brain, pregnant Sprague-Dawley rats were exposed once to 0.3 ppm of O3 or filtered air (FA) …

Early Technology Exposure And Academic Performance In Generation Alpha: Reduced Attention Span And Ability To Multitask, Sanjana Gupta

UROP Posters

The increasing prevalence of handheld devices in the lives of young children inspired this research, particularly regarding their potential impact on attention spans and cognitive development in Generation Alpha. Early exposure to tablets and smartphones before the age of seven coincides with critical periods of neuroplasticity, during which the brain is highly receptive to environmental influences. This matters because attention and cognitive skills formed in childhood lay the foundation for academic success and long-term personal development, and the shift toward digital learning platforms in schools may have significant consequences.

This study aimed to investigate whether early exposure to handheld devices …

Exploring Belonging And Success In First Generation College Students With Disabilities, Cael Sinclair, Molly Taylor, Sharon Zumbrunn

UROP Posters

As colleges create initiatives to admit and accommodate marginalized students, the struggles of those marginalized students are becoming increasingly impactful and present. Research suggests that students’ sense of social belonging is often connected to student academic success (Connell & Wellborn 1991). However, marginalized students often experience a lower sense of belonging, particularly students who are the first in their families to go to college (Stebleton et al. 2014), and those who identify as disabled (Leake & Stodden 2014). The present study evaluated how the strengths and experiences of first-generation college students with disabilities impacted their belonging and academic success in …

Autonomous Strike Uavs For Counterterrorism Missions: Challenges And Preliminary Solutions, Meshari Aljohani, Ravi Mukkamala, Stephan Olariu

Computer Science Faculty Publications

UAVs are becoming a crucial tool in modern warfare, primarily due to their cost-effectiveness, risk reduction, and ability to perform a wider range of activities. The use of autonomous UAVs to conduct strike missions against highly valuable targets is the focus of this research. Due to developments in ledger technology, smart contracts, and machine learning, such activities formerly carried out by professionals or remotely flown UAVs are now feasible. Our study provides the first in-depth analysis of challenges and potential solutions for successful implementation of an autonomous UAV mission.

Building Datasets To Support Information Extraction And Structure Parsing From Electronic Theses And Dissertations, William A. Ingram, Jian Wu, Sampanna Yashwant Kahu, Javaid Akbar Manzoor, Bipasha Banerjee, Aman Ahuja, Muntabir Hasan Choudhury, Lamia Salsabil, Winston Shields, Edward A. Fox

Computer Science Faculty Publications

Despite the millions of electronic theses and dissertations (ETDs) publicly available online, digital library services for ETDs have not evolved past simple search and browse at the metadata level. We need better digital library services that allow users to discover and explore the content buried in these long documents. Recent advances in machine learning have shown promising results for decomposing documents into their constituent parts, but these models and techniques require data for training and evaluation. In this article, we present high-quality datasets to train, evaluate, and compare machine learning methods in tasks that are specifically suited to identify and …

Autonomous Strike Uavs In Support Of Homeland Security Missions: Challenges And Preliminary Solutions, Meshari Aljohani, Ravi Mukkamala, Stephan Olariu

Computer Science Faculty Publications

Unmanned Aerial Vehicles (UAVs) are becoming crucial tools in modern homeland security applications, primarily because of their cost-effectiveness, risk reduction, and ability to perform a wider range of activities. This study focuses on the use of autonomous UAVs to conduct, as part of homeland security applications, strike missions against high-value terrorist targets. Owing to developments in ledger technology, smart contracts, and machine learning, activities formerly carried out by professionals or remotely flown UAVs are now feasible. Our study provides the first in-depth analysis of the challenges and preliminary solutions for the successful implementation of an autonomous UAV mission. Specifically, we …

Archiving Digital Marketing: Examining Preservation Of Dynamic Content On The Web Through The Lens Of Online Advertisements, Christopher Rauch, Alex H. Poole, Travis Reid, Michele C. Weigle, Michael L. Nelson, Faryaneh Poursardar, Mat Kelly

Computer Science Faculty Publications

The transition to digital marketing has revolutionized advertising, reflecting and shaping societal norms and trends. The “Saving Ads” project addresses the challenges of preserving these ephemeral digital artifacts, essential for understanding the evolution of advertising and its socio-cultural impact. The initiative focuses on technical solutions for archiving dynamic online ads and enhancing access to these critical resources for future scholarship. By examining the preservation of online advertisements and suggesting improved approaches for archiving dynamic online content, this project contributes to the documentation of digital history.

The Combined Focal Loss And Dice Loss Function Improves The Segmentation Of Beta-Sheets In Medium-Resolution Cryo-Electron-Microscopy Density Maps, Yongcheng Mu, Thu Nguyen, Bryan Hawickhorst, Willy Wriggers, Jiangwen Sun, Jing He

Computer Science Faculty Publications

Although multiple neural networks have been proposed for detecting secondary structures from medium-resolution (5–10 Å) cryo-electron microscopy (cryo-EM) maps, the loss functions used in the existing deep learning networks are primarily based on cross-entropy loss, which is known to be sensitive to class imbalances. To monitor and tune the performance of various loss functions for the secondary structure detection problem, we investigated five loss functions: cross-entropy, Focal loss, Dice loss, and two combined loss functions. Using a U-Net architecture in our DeepSSETracer method and a dataset composed of 1,355 box-cropped atomic-structure/density-map pairs, we found that a newly designed loss function …

Gwid: An R Package And Shiny Application For Genome-Wide Analysis Of Ibd Data, Soroush Mahmoudiandehkordi, Mehdi Maadooliat, Steven J. Schrodi

Mathematical and Statistical Science Faculty Research and Publications

Summary

Genome-wide identity by descent (gwid) is an R package developed for the analysis of identity-by-descent (IBD) data pertaining to dichotomous traits. This package offers a set of tools to assess differential IBD levels for the two states of a binary trait, yielding informative and meaningful results. Furthermore, it provides convenient functions to visualize the outcomes of these analyses, enhancing the interpretability and accessibility of the results. To assess the performance of the package, we conducted an evaluation using real genotype data derived from the SNPs to investigate rheumatoid arthritis susceptibility from the Marshfield Clinic Personalized Medicine Research Project.

Availability …

Predicting Fluorescence To Singlet Oxygen Generation Quantum Yield Ratio For Bodipy Dyes Using Qspr And Machine Learning, Platon P. Chebotaev, Andrey A. Buglak, Aimee Sheehan, Mikhail A. Filatov

Research Outputs: 2025-Present

No abstract provided.

Extremal Graphs For Widom–Rowlinson Colorings In K-Chromatic Graphs, John Engbers, Aysel Erey

Mathematical and Statistical Science Faculty Research and Publications

The Widom–Rowlinson graph, H_WR , is the fully looped path on three vertices. Let hom(G,H_WR) be the number of graph homomorphisms from G to H_WR or, equivalently, the number of H_WR-colorings of G. We investigate extremal graphs for hom(G,H_WR) for G in the family of k-chromatic graphs subject to various connectivity requirements. In particular, we determine the graphs G maximizing hom(G,H_WR) in the families of n-vertex k-chromatic graphs, n-vertex connected k-chromatic graphs, n-vertex k-chromatic graphs with c components, n …