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Articles 186001 - 186030 of 193118
Full-Text Articles in Entire DC Network
Heat Stress Promotes Osteogenic And Odontogenic Differentiation Of Stem Cells From Apical Papilla Via Glucose-Regulated Protein 78-Mediated Autophagy, Xiaolan Zhang, Zhou Wei, Yunlong Xu
Heat Stress Promotes Osteogenic And Odontogenic Differentiation Of Stem Cells From Apical Papilla Via Glucose-Regulated Protein 78-Mediated Autophagy, Xiaolan Zhang, Zhou Wei, Yunlong Xu
Journal of Dental Sciences
Abstract Background/purpose Heat stress is essential for improving the efficacy of mesenchymal stem cell (MSC)-based regeneration medicine. However, it is still unclear whether and how heat stress influences the differentiation of stem cells from apical papilla (SCAPs). This research aimed to explore the potential mechanism of glucose-regulated protein 78 (GRP78) in regulating differentiation under heat stress in SCAPs. Materials and methods The proliferation ability was assessed using the 5-Ethynyl-2’- deoxyuridine (EdU) assay, cell counting kit assay (CCK-8), and flow cytometry (FCM). The osteogenic and odontogenic differentiation capacities were investigated through Western blot, quantitative reverse transcription polymerase chain reaction (qRT-PCR), alkaline …
Enhancement Of Titanium Surfaces Using Different Acid Solutions At Room Temperature To Improve Bone Cell Responses, Wei-Jen Chang, Thu Linn, Eisner Salamanca, Chun-Yu Ho, Yi-Fan Wu, Hao-Chun Chiu, Ying-Sui Sun
Enhancement Of Titanium Surfaces Using Different Acid Solutions At Room Temperature To Improve Bone Cell Responses, Wei-Jen Chang, Thu Linn, Eisner Salamanca, Chun-Yu Ho, Yi-Fan Wu, Hao-Chun Chiu, Ying-Sui Sun
Journal of Dental Sciences
Abstract Background/purpose Early osseointegration of titanium (Ti) dental implants relies on the surface topography. Surface modification of Ti seeks to enhance bone regeneration around implants. Acid etching is the simple, less technique sensitive and cost-effective technique for surface treatment. The purpose of this study was to elucidate the simplified acid etching technique at room temperature lies in its capacity to enhance both physical properties and biological reactions relevant to bone. Materials and methods Utilizing sulfuric acid (H2SO4) and hydrochloric acid (HCl), five distinct acid solutions were prepared, and the acid etching process was executed at five different time points at …
Ex-Vivo Investigation Of Human Salivary Microbial Growth With Lysogeny Broth For Translational Research–A Pilot Study, Chin-Wei Wang, Yu-Hsin Yang, Jing-Jie Yu, Hsin-Ying Han, Wei-Min Chang
Ex-Vivo Investigation Of Human Salivary Microbial Growth With Lysogeny Broth For Translational Research–A Pilot Study, Chin-Wei Wang, Yu-Hsin Yang, Jing-Jie Yu, Hsin-Ying Han, Wei-Min Chang
Journal of Dental Sciences
Abstract Background/purpose Salivary microbiome has become a surrogate indicator of oral disease due to its collective reservoirs and convenience in sampling. However, failed clinical trials often lead to wastes of resources, indicating a need for preclinical models. In this pilot study, we aimed to compare the salivary microbiome by metagenomics analysis before and after lysogeny broth culture for prospective translational studies. Materials and methods The study cohort included seven patients with severe periodontitis (Stage III/IV, Grade C), from whom unstimulated saliva was collected. The salivary microbiome was sequenced over the 16S rRNA gene V3–V4 hypervariable regions at baseline and after …
Effect Of Pulp-Chamber Lateral Wall Thickness And Number On Fracture Resistance In Endocrown-Restored Molars: An In Vitro Study, Zhi Li, Jun-Xin Zhu, Yong-Xiang Xu, Xu-Dong Bao, Xiao-Yan Wang
Effect Of Pulp-Chamber Lateral Wall Thickness And Number On Fracture Resistance In Endocrown-Restored Molars: An In Vitro Study, Zhi Li, Jun-Xin Zhu, Yong-Xiang Xu, Xu-Dong Bao, Xiao-Yan Wang
Journal of Dental Sciences
Abstract Background/purpose It remains unclear how the thickness and number of pulp-chamber lateral walls (PCLWs) affects fracture resistance in endocrown-restored teeth. Materials and methods 64 mandibular molars were collected and randomly divided into eight groups (n = 8). In group C (control group), the teeth were untreated. In groups T1, T2, and T3, the teeth were subjected to endodontic treatment and restored with nanoceramic endocrowns exhibiting different PCLW thicknesses (T1: 0.5 mm, T2: 1.0 mm, and T3: 1.5 mm). In groups N1, N2, N3, and N4, the numbers of missing PCLWs in prepared teeth were one (N1), two (N2), three …
Evaluating The Image Recognition Capabilities Of Gpt-4v And Gemini Pro In The Japanese National Dental Examination, Masaki Morishita, Hikaru Fukuda, Kosuke Muraoka, Shino Yamaguchi, Taiji Nakamura, Izumi Yoshioka, Shuji Awano, Kentaro Ono
Evaluating The Image Recognition Capabilities Of Gpt-4v And Gemini Pro In The Japanese National Dental Examination, Masaki Morishita, Hikaru Fukuda, Kosuke Muraoka, Shino Yamaguchi, Taiji Nakamura, Izumi Yoshioka, Shuji Awano, Kentaro Ono
Journal of Dental Sciences
Abstract Background/purpose OpenAI's GPT-4V and Google's Gemini Pro, being Large Language Models (LLMs) equipped with image recognition capabilities, have the potential to be utilized in future medical diagnosis and treatment, ands serve as valuable educational support tools for students. This study compared and evaluated the image recognition capabilities of GPT-4V and Gemini Pro using questions from the Japanese National Dental Examination (JNDE) to investigate their potential as educational support tools. Materials and methods We analyzed 160 questions from the 116th JNDE, administered in March 2023, using ChatGPT-4V, and Gemini Pro, which have image recognition functions. Standardized prompts were used for …
Titanium Particle-Induced Inflammasome In Human Gingival Epithelial Cells, Akira Hasuike, Shin Wakuda, Kyoko Fujiwara, Ryo Sakai, Akhilanand Chaurasia, Toshio Uchiyama, Shuichi Sato
Titanium Particle-Induced Inflammasome In Human Gingival Epithelial Cells, Akira Hasuike, Shin Wakuda, Kyoko Fujiwara, Ryo Sakai, Akhilanand Chaurasia, Toshio Uchiyama, Shuichi Sato
Journal of Dental Sciences
Abstract Background/purpose Peri-implantitis remains a substantial challenge. This study investigated the effect of titanium particles on human oral epithelial cells, focusing on the nucleotide-binding domain and leucine-rich repeat protein (NLRP) 3 inflammasome. Materials and methods The Ca9-22 human gingival epithelial cell line was subjected to incubation with titanium particles. To evaluate cell viability, the MTT assay was employed. Total RNA was extracted, and messenger RNA (mRNA) expressions of COX2 , TGF-β1 , NLRP1 , NLPR3 , CASP1 , and AIM2 were analyzed. The concentration of interleukin (IL)1β in cell supernatants was quantified through enzyme-linked immunosorbent assay. Intracellular reactive oxygen species …
Elucidating Interfacial Failure Of Cervical Restorations Using Damage Mechanics: A Finite Element Analysis, Po-Chun Tseng, Shu-Fen Chuang, Ellen Schulz-Kornas, Karl-Heinz Kunzelmann, Andreas Kessler
Elucidating Interfacial Failure Of Cervical Restorations Using Damage Mechanics: A Finite Element Analysis, Po-Chun Tseng, Shu-Fen Chuang, Ellen Schulz-Kornas, Karl-Heinz Kunzelmann, Andreas Kessler
Journal of Dental Sciences
Abstract Background/purpose Although clinical studies have suggested a link between non-axial forces and reduced longevity of cervical restorations, the underlying mechanisms require further numerical investigation. This in-silico study employed a cohesive zone model (CZM) to investigate interfacial damage in a cervical restoration subjected to different load directions. Materials and methods A plane strain model of a maxillary premolar was established, with a wedge-shaped buccal cervical restoration. To simulate debonding, the restoration-tooth interface was modeled by the CZM, which defines the strain-softening damage behavior based on interfacial stress and fracture energy. Occlusal loads were applied in three different directions: (1) obliquely …
Soft Coral Lobophytum Crassum Extract Inhibits Migration And Induces Apoptosis Capabilities In Human Oral Squamous Cell Carcinoma Cells, Shih-Min Wang, Mei-Chin Lu, Yu-Ming Hsu, Chun-Chung Huang, Chih-Yuan Fang, Chuan-Hang Yu, Pin Ju Chueh, Cheng-Chia Yu, Shiao-Pieng Lee
Soft Coral Lobophytum Crassum Extract Inhibits Migration And Induces Apoptosis Capabilities In Human Oral Squamous Cell Carcinoma Cells, Shih-Min Wang, Mei-Chin Lu, Yu-Ming Hsu, Chun-Chung Huang, Chih-Yuan Fang, Chuan-Hang Yu, Pin Ju Chueh, Cheng-Chia Yu, Shiao-Pieng Lee
Journal of Dental Sciences
Abstract Background/purpose The extract of the soft coral Lobophytum crassum has shown an anti-cancer activity in various cancer cells. However, its effect on the oral squamous cell carcinoma cell (OSCC) lines remains unclear. The purpose of this study is to investigate the anti-cancer effects of the extract of L. crassum (C127) on the OSCC cells. Materials and methods This study evaluated the effects of the soft coral extract of L. crassum (C127) on SAS and Ca9-22 cells, cell viability, migration ability, and apoptosis. Electric cell-substrate impedance sensing (ECIS) was parallelly used on SAS cells to confirm the results. Results C127 …
Progesterone Affects Periodontitis In Perimenopausal Women And In An Experimental Rat Model, Fei-Fei Niu, Ying Man, Xinyue Zhang, Xiaozhen Wang, Siyu Liu, Pishan Yang
Progesterone Affects Periodontitis In Perimenopausal Women And In An Experimental Rat Model, Fei-Fei Niu, Ying Man, Xinyue Zhang, Xiaozhen Wang, Siyu Liu, Pishan Yang
Journal of Dental Sciences
Abstract Background/purpose Progesterone (PG) is sex steroid hormone that commonly used to control menopausal symptoms, but its exact role in periodontitis remains unclear. This study aimed to investigate the effects of PG on periodontitis in perimenopausal women and in an experimental rat model. Materials and methods Total 412 perimenopausal women with periodontitis and a history of PG deficiency-induced uterine dysfunctional bleeding were enrolled, among which 209 women had been treated with PG. The alveolar bone height (ABH) and bone mineral density (BMD) were measured by cone beam computed tomography in the full-mouth. Additionally, a ligation-induced rat model of periodontitis was …
Relationship Between Oral Health Literacy And Changes In Self-Assessment Of Oral Health During Covid-19, Naoko Adachi, Yuko Hirota, Kanade Ito, Kayoko Shinada, Yuji Kabasawa
Relationship Between Oral Health Literacy And Changes In Self-Assessment Of Oral Health During Covid-19, Naoko Adachi, Yuko Hirota, Kanade Ito, Kayoko Shinada, Yuji Kabasawa
Journal of Dental Sciences
Abstract Background/purpose Health literacy is thought to play a major role in implementing health behaviors, such as preventing coronavirus disease 2019 (COVID-19). In this study, we aimed to examine the relationship between oral health literacy (OHL), dietary literacy (DL), and changes in oral health and eating habits during the COVID-19 pandemic. Materials and methods The self-assessment questionnaire, including questions on oral and dietary conditions for each period of the COVID-19 pandemic, sources of information, OHL, DL, and frequency of COVID-19 prevention measures, was administered using a web research company. All participants were divided into low- and high-literacy groups based on …
The Effect Of Autologous Demineralized Dentin Matrix On Postoperative Complications And Wound Healing Following Lower Third Molar Surgery: A Split-Mouth Randomized Clinical Trial, Son Hoang Le, Nhan Nguyen, Bich-Ly Nguyen
The Effect Of Autologous Demineralized Dentin Matrix On Postoperative Complications And Wound Healing Following Lower Third Molar Surgery: A Split-Mouth Randomized Clinical Trial, Son Hoang Le, Nhan Nguyen, Bich-Ly Nguyen
Journal of Dental Sciences
Abstract Background/purpose Autologous dentin materials are among the most promising bone substitutes for preventing osseous defects on the distal side of the lower second molar. This study aimed to investigate the effects of autologous demineralized dentin matrix on postoperative complications and wound healing after lower third molar surgery. Materials and methods Thirteen patients with bilateral symmetrical lower third molars participated in this split-mouth randomized clinical trial. After removal surgery, one socket of the lower third molar was grafted with dentin material (demineralized dentin matrix side), and a piece of collagen sponge was used for the tooth socket of the remaining …
Effect Of A Modified Methyl Methacrylate-P-Styrene Sulfonic Acid Copolymer-Based Gel Desensitizer On Dentin Permeability And Tubule Occlusion In Human Dentin In Vitro, Kanittha Kijsamanmith, Athimas Chatanan, Varunee Kerdvongbundit, Thanwarat Aroonrangsee, Noppakun Vongsavan
Effect Of A Modified Methyl Methacrylate-P-Styrene Sulfonic Acid Copolymer-Based Gel Desensitizer On Dentin Permeability And Tubule Occlusion In Human Dentin In Vitro, Kanittha Kijsamanmith, Athimas Chatanan, Varunee Kerdvongbundit, Thanwarat Aroonrangsee, Noppakun Vongsavan
Journal of Dental Sciences
Abstract Background/purpose Tubular occlusion is an effective method to treat dentin hypersensitivity. This study aimed to determine the effect of a modified methyl methacrylate-p-styrene sulfonic acid copolymer-based gel desensitizer on dentin permeability and tubule occlusion in extracted human premolars. Materials and methods Hydraulic conductance (HC) measurement (n = 50) and scanning electron microscopy (SEM; n = 64) were performed. Tooth specimens were divided into 6 groups and treated with: G1, distilled water for 30 s; G2, distilled water for 5 min; G3, gel desensitizer for 30 s; G4, gel desensitizer for 5 min; G5, 3% potassium oxalate for 30 s; …
Optimized Design For Using Of Double-Barrel Vascularized Fibular Flap In Various Types Of Mandibular Defects, Ming Li, Lidong Wang, Wen Ma, Changbin Zhang, Sihang Wang, Gending Nie
Optimized Design For Using Of Double-Barrel Vascularized Fibular Flap In Various Types Of Mandibular Defects, Ming Li, Lidong Wang, Wen Ma, Changbin Zhang, Sihang Wang, Gending Nie
Journal of Dental Sciences
Abstract Background/purpose The functional and aesthetic reconstruction of the mandible can be achieved by using the double-barrel vascularized free fibula flap. The purpose of this study was to use multiple integrated techniques to more effectively reconstruct the mandible, some contains of our unique ideas. Materials and methods 21 patients were included in this study. Computed tomography (CT) data of the patient's mandible and fibula were acquired preoperatively. Individualized surgical simulation was performed by using computer-aided surgical simulation (CASS) technology, about 6 kinds of integrated 3D design ideas were simultaneously perfectly transferred to real surgery. The accuracy of reconstruction was evaluated …
A Review Of The Roles Of Exosomes In Salivary Gland Diseases With An Emphasis On Primary Sjögren's Syndrome, Yubin Cao, Xianzhen Cui, Liu Liu, Chengchen Duan, Suning Mao, Guanru Wang, Honglin Li, Cheng Miao
A Review Of The Roles Of Exosomes In Salivary Gland Diseases With An Emphasis On Primary Sjögren's Syndrome, Yubin Cao, Xianzhen Cui, Liu Liu, Chengchen Duan, Suning Mao, Guanru Wang, Honglin Li, Cheng Miao
Journal of Dental Sciences
Abstract Salivary gland diseases encompass a broad range of conditions, including autoimmune, inflammatory, obstructive, and neoplastic disorders, significantly impacting oral health and overall well-being. Recent research has highlighted the crucial role of exosomes, small extracellular vesicles, in these diseases. Exosomes mediate intercellular communication by transferring bioactive molecules such as proteins, microRNAs, and lipids, positioning them as potential diagnostic biomarkers and therapeutic agents. In primary Sjögren's syndrome (pSS), exosomes derived from Epstein–Barr virus-infected B cells and activated T cells transfer key microRNAs that impair calcium signaling, contributing to glandular dysfunction. Exosome-based biomarkers like Ro/SSA and La/SSB, found in saliva, serum, and …
Tooth Extraction After Transfusion Of Fresh Frozen Plasma In A Severe Factor Xi Deficiency (Hemophilia C) Patient, Hsin-Yang Liang, Chun-Pin Chiang
Tooth Extraction After Transfusion Of Fresh Frozen Plasma In A Severe Factor Xi Deficiency (Hemophilia C) Patient, Hsin-Yang Liang, Chun-Pin Chiang
Journal of Dental Sciences
No abstract provided.
2,3,5,4′-Tetrahydroxystilbene-2-O-Β-D-Glucoside–Stimulated Dental Pulp Stem Cells-Derived Exosomes For Wound Healing And Bone Regeneration, Sheng-Yang Lee, Tzu-Yu Lin, Tung-Yung Huang, Hsien-Chung Chiu, Yao-Yu Chung Chung, Wei-Chun Lin, Hung-Yun Lin
2,3,5,4′-Tetrahydroxystilbene-2-O-Β-D-Glucoside–Stimulated Dental Pulp Stem Cells-Derived Exosomes For Wound Healing And Bone Regeneration, Sheng-Yang Lee, Tzu-Yu Lin, Tung-Yung Huang, Hsien-Chung Chiu, Yao-Yu Chung Chung, Wei-Chun Lin, Hung-Yun Lin
Journal of Dental Sciences
Abstract Background/purpose -2,3,5,4′-tetrahydroxystilbene-2-O-β-D-glucoside (THSG) is a bioactive component in the Chinese herb Polygonum multiflorum, recognized for its anti-inflammatory and lipid-lowering properties. Human dental pulp stem cells (hDPSCs) have excellent capabilities in tooth regeneration, wound healing, and neural repair. The exosomes (Exo) released by hDPSCs contain bioactive molecules that influence cell proliferation, differentiation, and immune responses. Therefore, we aimed to unveil the potential of THSG-Exo and evaluate its regenerative capabilities through the in vitro experiment and rat bone defect model. Materials and methods The effects of hDPSC-derived exosomes, with or without THSG treatment, on repair and bone regeneration were evaluated through …
Comparisons Of Precision And Trueness Of Digital Dental Casts Produced By Desktop Scanners And Intraoral Scanners, Chung-Pin Chiang, Chun-Chao Chuang, Feng-Chou Cheng, Mu-Hsiung Chen, Wei-Chun Lin
Comparisons Of Precision And Trueness Of Digital Dental Casts Produced By Desktop Scanners And Intraoral Scanners, Chung-Pin Chiang, Chun-Chao Chuang, Feng-Chou Cheng, Mu-Hsiung Chen, Wei-Chun Lin
Journal of Dental Sciences
Abstract Background/purpose Different types of scanners are gradually used to produce digital dental casts in the current dental practice. This study tested the accuracy of the three desktop scanners and two intraoral scanners and evaluated whether the desktop scanners had higher precision than the intraoral scanners. Materials and methods This study used the three desktop and two intraoral scanners to scan a standard dental cast 5 times. The 5 digital casts produced by the same scanner were compared each other to study the precision errors of each scanner. Moreover, 5 sets of the 5 digital casts produced by the 5 …
High-Precision And Non-Invasive Measurement Of Crestal Bone Level By Optical Coherence Tomography, Shyh-Yuan Lee, Wei-Ting Chang, Dong-Yuan Lyu, Yu-Lin Lai, Jui-Ying Yen, Ya-Chi Chen
High-Precision And Non-Invasive Measurement Of Crestal Bone Level By Optical Coherence Tomography, Shyh-Yuan Lee, Wei-Ting Chang, Dong-Yuan Lyu, Yu-Lin Lai, Jui-Ying Yen, Ya-Chi Chen
Journal of Dental Sciences
Abstract Background/purpose Identifying crestal bone level (CBL) on the buccal and lingual aspects poses challenges in conventional dental radiographs. Given that optical coherence tomography (OCT) has the capability to non-invasively provide in-depth information about the periodontium, this in vitro study aimed to assess whether OCT can effectively identify periodontal landmarks and measure CBL in the presence of gingiva. Materials and methods An in-house handheld scanning probe connected to a 1310-nm swept-source OCT (SS-OCT) system, along with self-developed algorithms were employed to measure the CBL in dental models with artificial gingiva. Markers were positioned 0.5 mm above the artificial gingival margin …
A Scientometric Study On Research Trends And Characteristics Of Oral Leukoplakia And Oral Lichen Planus, Xuemin Shen, Wei Liu, Zhengyu Shen
A Scientometric Study On Research Trends And Characteristics Of Oral Leukoplakia And Oral Lichen Planus, Xuemin Shen, Wei Liu, Zhengyu Shen
Journal of Dental Sciences
Abstract Background/purpose Oral leukoplakia (OLK) and oral lichen planus (OLP) represent two common oral potentially malignant disorders. It would be interesting to know scientific output and characteristics of studies on OLK and OLP. Materials and methods This study aimed to investigate and compare scientometric characteristics of articles on OLK and OLP in the Scopus database, with emphasis on the analysis of the keywords that can reflect research directions and topics of concern. Results A total of 1,191 and 2,288 papers on OLK and OLP were retrieved in the Scopus database, respectively. The total citation count was 31,859 and the h …
A Scientometric Study On Research Trends And Characteristics Of Discoid Lupus Erythematosus, Wei Liu, Yun Wang, Yuhan Zhu, Chenping Zhang
A Scientometric Study On Research Trends And Characteristics Of Discoid Lupus Erythematosus, Wei Liu, Yun Wang, Yuhan Zhu, Chenping Zhang
Journal of Dental Sciences
Abstract Background/purpose Discoid lupus erythematosus (DLE) serves as an interdisciplinary disease involved in dermatology and stomatology in many cases. The purpose of this study was to analyze the scientometric characteristics and research trends of DLE. Materials and methods All the papers on DLE were comprehensively retrieved from the Scopus database. Discipline comparison (dermatology versus others) and chronological comparison (before 2005 versus 2005–2024) were performed, so that the number of papers can be to some extent compared in the analysis. Results Among all the 1239 papers on DLE, 738 (59.6 %) were published by dermatologists. Diagnosis aspect, skin manifestation, facial dermatoses, …
Oleanolic Acid Inhibits Aldo-Keto Reductase Family 1 Member B10-Induced Cancer Stemness And Avoids Cisplatin-Based Chemotherapy Resistance Via The Snail Signaling Pathway In Oral Squamous Cell Carcinoma Cell Lines, Shih-Jung Cheng, Hui-Hsin Ko, Han-Yi E. Chou, Hsin-Han Hou, Wei-Ting Kuo, Wei-Wen Liu, Mark Yen-Ping Kuo
Oleanolic Acid Inhibits Aldo-Keto Reductase Family 1 Member B10-Induced Cancer Stemness And Avoids Cisplatin-Based Chemotherapy Resistance Via The Snail Signaling Pathway In Oral Squamous Cell Carcinoma Cell Lines, Shih-Jung Cheng, Hui-Hsin Ko, Han-Yi E. Chou, Hsin-Han Hou, Wei-Ting Kuo, Wei-Wen Liu, Mark Yen-Ping Kuo
Journal of Dental Sciences
Abstract Background/purpose Oral squamous cell carcinoma (OSCC) is a common malignancy often associated with poor prognosis due to chemoresistance. In this study, we investigated whether arecoline, a major alkaloid in betel nuts, can stimulate aldo-keto reductase family 1 member B10 (AKR1B10) levels in OSCC, promoting cancer stemness and leading to resistance to cisplatin (CDDP)-based chemotherapy. Materials and methods Gain- and Loss- of AKR1B10 functions were analyzed using WB and q-PCR of OSCC cells. Stemness, epithelial mesenchymal transition (EMT) markers, and CDDP drug resistance in overexpressed AKR1B10 were also identified. Results Upregulated AKR1B10 in OSCC significantly increased cell motility and aggregation. …
Current Challenges Of Dental Laboratory In Taiwan: The Perspectives From A Senior Certified Dental Technician In A Dental Laboratory Attached To A Teaching Hospital, Feng-Chou Cheng, Wei-Chun Lin, Chun-Pin Chiang
Current Challenges Of Dental Laboratory In Taiwan: The Perspectives From A Senior Certified Dental Technician In A Dental Laboratory Attached To A Teaching Hospital, Feng-Chou Cheng, Wei-Chun Lin, Chun-Pin Chiang
Journal of Dental Sciences
No abstract provided.
The Investigation Of Thermal Behavior And Temperature Analysis Of Three Types Of Contemporary Gutta-Percha Points, Sung-Chih Hsieh, Hsin-Hui Wang, Liang-Han Chiu, Yung-Hao Hsu
The Investigation Of Thermal Behavior And Temperature Analysis Of Three Types Of Contemporary Gutta-Percha Points, Sung-Chih Hsieh, Hsin-Hui Wang, Liang-Han Chiu, Yung-Hao Hsu
Journal of Dental Sciences
Abstract Background/purpose The impact of thermal behavior on the clinical performance of gutta-percha points (GP) is unclear. This study aimed to investigate the thermal behavior of three different types of GP and their temperature changes (TC) in a simulated clinical environment. Materials and methods The GP tested were Conform Fit® Gutta-Percha Points (CF), Autofit™ Feathered Tip Gutta Percha (AF), and Gutta Percha Root Canal Points (GC). The phase transition temperatures of the samples were analyzed using differential scanning calorimetry (DSC). The TC at the tips of the GP was examined with the heat source positioned at specific distances from the …
Improving Osteogenic Properties Of Zirconia Ceramic Via Glow Discharge Plasma-Enhanced Deposition Of Amine Organic Compound, Wei-Jen Chang, Lwin Moe Aung, Ting-Yi Renn, Jerry Chin-Yi Lin, Eisner Salamanca, Yi-Fan Wu, Yu-Hwan Pan, Nai-Chia Teng, Haw-Ming Huang, Ying-Sui Sun
Improving Osteogenic Properties Of Zirconia Ceramic Via Glow Discharge Plasma-Enhanced Deposition Of Amine Organic Compound, Wei-Jen Chang, Lwin Moe Aung, Ting-Yi Renn, Jerry Chin-Yi Lin, Eisner Salamanca, Yi-Fan Wu, Yu-Hwan Pan, Nai-Chia Teng, Haw-Ming Huang, Ying-Sui Sun
Journal of Dental Sciences
Abstract Background/purpose Osseointegration potential is greatly depended on the interaction between bone cells and dental implant surface. Since zirconia ceramic has a bioinert surface, functionalization of the surface with an organic compound allylamine was conducted to overcome its drawback of minimal interaction with the surrounding bone. Materials and methods The zirconia surface was initially treated with argon glow discharge plasma (GDP), then combined with amine plasma at three different conditions of 50-W, 75-W and 85-W, to prepare the final samples. The surface characteristics and cell biocompatibility were then evaluated. Results Surface morphology analysis revealed a bulbous pattern on allylamine-treated sample …
Mir-508-5p Suppresses Osteogenic Differentiation Of Human Periodontal Ligament Stem Cells Via Targeting Sex-Determining Region Y-Related Hmg-Box 11, Jing Guo, Xiang-Ying Ouyang, Jian-Ru Liu, Wen-Yi Liu, Yuan-Bo Wang
Mir-508-5p Suppresses Osteogenic Differentiation Of Human Periodontal Ligament Stem Cells Via Targeting Sex-Determining Region Y-Related Hmg-Box 11, Jing Guo, Xiang-Ying Ouyang, Jian-Ru Liu, Wen-Yi Liu, Yuan-Bo Wang
Journal of Dental Sciences
Abstract Background/Purpose The local inflammatory microenvironment created by periodontitis negatively impacts periodontal tissue regeneration, necessitating the development of methods to enhance the regenerative capacity of stem cells. This study explored the regulatory role and underlying mechanism of miR-508-5p in the osteogenic differentiation of human periodontal ligament stem cells (hPDLSCs). Materials and methods The regulatory roles of miR-508–5p in osteogenic differentiation of hPDLSCs were investigated through its inhibition or overexpression. Expression of the sex-determining region Y-related HMG-box 11 (SOX11) and osteogenic markers was analyzed using Western blot and real-time PCR. Osteogenesis was measured using alizarin red S (ARS) staining and alkaline …
Phosphotungstic Acid-Enhanced Micro-Computed Tomography And Rna Sequencing Provide A New Perspective On Temporomandibular Joint Arthritis Induced By Complete Freund's Adjuvant And Collagen-Induced Arthritis In Rat Models, Mu-Chen Yang, Ding-Han Wang, Kim-Xuyen Nguyen, Trang Tran, Po-Han Wu, Guang Hong, Yu-Min Lin, Yi-Chen Hsu, Cheng-Chieh Yang, Yu-Cheng Lin, Wun-Eng Hsu, Ming-Lun Hsu
Phosphotungstic Acid-Enhanced Micro-Computed Tomography And Rna Sequencing Provide A New Perspective On Temporomandibular Joint Arthritis Induced By Complete Freund's Adjuvant And Collagen-Induced Arthritis In Rat Models, Mu-Chen Yang, Ding-Han Wang, Kim-Xuyen Nguyen, Trang Tran, Po-Han Wu, Guang Hong, Yu-Min Lin, Yi-Chen Hsu, Cheng-Chieh Yang, Yu-Cheng Lin, Wun-Eng Hsu, Ming-Lun Hsu
Journal of Dental Sciences
Abstract Background/Purpose Temporomandibular joint (TMJ) arthritis causes inflammation and degradation of the mandibular condylar cartilage and subchondral bone. Complete Freund's adjuvant (CFA) and collagen-induced arthritis (CIA) are models for studying TMJ arthritis. While micro-computed tomography (micro-CT) is crucial for three-dimensional (3D) bone analysis, it has limitations in imaging nonmineralized tissues. Phosphotungstic acid (PTA) enhances soft tissue contrast. However, research on the 3D imaging of mandibular condylar cartilage and the molecular mechanisms of CFA- and CIA-induced arthritis remains unclear. This study aimed to investigate the bone and PTA-stained cartilage in the mandibular condyle using 3D reconstruction and explore the characteristics of …
The Establishment Of Pulp Polyp-Derived Mesenchymal Stem Cells With Normal Karyotype, Ferry Sandra, Eko Fibryanto, Tien Suwartini, Anastasia Prahasti, Widya Wulandari, Andri Sutanto, Lyvia Juliana, Kyung Lee
The Establishment Of Pulp Polyp-Derived Mesenchymal Stem Cells With Normal Karyotype, Ferry Sandra, Eko Fibryanto, Tien Suwartini, Anastasia Prahasti, Widya Wulandari, Andri Sutanto, Lyvia Juliana, Kyung Lee
Journal of Dental Sciences
Abstract Background/Purpose Pulp polyp is often eliminated as dental waste. Pulp polyp cells were reported to have high proliferation activity which might be comprised of stem cells. However, little has been known on the presence of stem cells in the pulp polyp. Moreover, pulp polyp cells might contain chromosomal abnormality. The present study was conducted to investigate the presence of pulp polyp stem cells, which could later be propagated and confirmed as normal/non-pathogenic cells using karyotype analysis. Materials and methods Collected pulp polyps were minced, enzymatically digested, and cultured. Expression of mesenchymal stem cell (MSC) markers on pulp polyp cells …
Prognostic Nomogram For Proliferative Verrucous Leukoplakia, Yanning Zhang, Xinning Zhang, Zhiming Qin, Jing Yan, Binbin Li
Prognostic Nomogram For Proliferative Verrucous Leukoplakia, Yanning Zhang, Xinning Zhang, Zhiming Qin, Jing Yan, Binbin Li
Journal of Dental Sciences
Abstract Background Proliferative verrucous leukoplakia (PVL) is a special type of leukoplakia characterized by high rate of malignant transformation into oral squamous cell carcinoma (OSCC). This study aimed to analyze the canceration risk and prognostic factors of PVL and establish effective diagnostic and prognostic predictive models. Materials and methods A total of 467 patients were enrolled, including 170 cases of PVL. The independent risk and prognostic factors of PVL were analyzed by univariable and multivariable logistic regression. Nomogram models were constructed to predict the canceration risk and prognosis of PVL. The predictive power was evaluated by Hosmer–Lemeshow test, receiver operating …
A Scientometric Study Of Syphilis Research By Dermatologists And Stomatologists: Underpinning Their Roles In Public Health, Wei Liu, Yeqiang Li, Chenxi Li, Xuemin Shen, Zhengyu Shen
A Scientometric Study Of Syphilis Research By Dermatologists And Stomatologists: Underpinning Their Roles In Public Health, Wei Liu, Yeqiang Li, Chenxi Li, Xuemin Shen, Zhengyu Shen
Journal of Dental Sciences
Abstract Background/Purpose The Lancet Infectious Diseases launched a call to action for dermatologists in the rise of syphilis. In practice, dermatologists and stomatologists perform early diagnoses of syphilis and refer patients to adequate treatment. Materials and methods This scientometric study aimed to investigate and compare research trends and characteristics of syphilis publications by dermatologists and stomatologists in the Scopus database, with emphasis on the analysis of the keywords that can reflect research directions and topics of concern. Results Among 18,120 papers on syphilis, 1981 (10.9%) and 201 (1.1%) were published by dermatologists and stomatologists, respectively. The total citation count was …
Oral Care Methods To Reduce Salivary Bacteria In Infants Undergoing Cardiac Surgery: A Randomized Controlled Trial, Madoka Funahara, Hiromi Honda, Kanako Nose, Megumi Aoki, Sakiko Soutome, Kenichi Yanagita, Atsuko Nakamichi
Oral Care Methods To Reduce Salivary Bacteria In Infants Undergoing Cardiac Surgery: A Randomized Controlled Trial, Madoka Funahara, Hiromi Honda, Kanako Nose, Megumi Aoki, Sakiko Soutome, Kenichi Yanagita, Atsuko Nakamichi
Journal of Dental Sciences
Abstract Background/purpose Complications, such as postoperative pneumonia, can occur after pediatric cardiac surgery; however, studies on related changes in perioperative oral bacterial counts are scarce. Herein, we investigated the changes in oral bacterial counts before and after surgery in infants who underwent cardiac surgery, as well as after oral care using an antiseptic mouthwash. Materials and methods A total of 102 infants who underwent congenital heart disease surgery were enrolled in this study. Preoperative oral care was provided using water and a sponge brush. Bacterial cultures were used to determine salivary bacterial counts before and after oral care. Postoperatively, the …