Digital Commons Network^™

Movian: Advancing Human Motion Analysis With 3d Visualization And Annotation, Trudi Di Qi, Isaac Browen, David Zhang, Hector M. Camarillo-Abad, Franceli L. Cibrian

Engineering Faculty Articles and Research

Human motion analysis, including data visualization and annotation, is crucial for understanding human behavior and intentions during various activities, aiding in the development of innovative tools that support independent living. Current wearable sensing technology provides rich 3D spatial movement data but generates multimodal complex datasets that require specialized skills for effective analysis. Despite the need, limited research exists on tools for effective visualization and easy annotation of such complex motion data. MoViAn (Motion Data Visualization and Annotation) is an innovative 3D data analysis system offering enriched visual representations of 3D human motion data (e.g., gaze, hand movements), along with an …

Jóvenes Y Memoria: Conflict And Vitality In Education For Human Rights, Bryan Harriss Jones

Graduate Liberal Studies Theses and Dissertations

In 2002, the Comisión Provincial por la Memoria (the Provincial Commission for Memory - CPM) of Argentina’s province of Buenos Aires (PBA) established Jóvenes y Memoria: Recordamos para el Futuro (Youth and Memory: We Remember for the Future – JyM), an elective program for secondary school students. JyM empowers students to create and communicate narratives about the history and current state of human rights based on investigations using primary sources. The goals of CPM include fostering historical memory and preventing the return of authoritarianism. JyM furthers these goals by building exemplary memory to inspire positive change in the present and …

Modeling Of Light Filamentation For Nonlinear Imaging And Waveguiding, Nicholas Bagley

Mathematics Theses and Dissertations

Ultrashort pulses are capable of extremely high powers; in addition to enabling various applications in defense, sensing, and imaging, they provide a useful arena in which to study nonlinear optical phenomena that are observable only at high intensities. Due to these effects, which can include ionization and thermal blooming, simulation of ultrashort pulse propagation is a complicated multiphysics problem. We provide an overview of techniques used to simulate the propagation of ultrashort pulses in the nonlinear regime, including the formation of light filaments due to the competition of Kerr self-focusing and defocusing (e.g. via plasma generation). We discuss both carrier-resolved …

The Texas Electorate's Views Of Health Care As A Human Right, Community Health Centers, And Certain Matters Of The Health Care Safety Net, Scott Elphingstone

Graduate Liberal Studies Theses and Dissertations

In a country in which the government does not recognize a right to health care,social safety nets are the last hope for persons without insurance or other means to pay for needed care. In United States, community health centers, hospital emergency rooms, and private charities comprise that safety net. Community health centers offer a practicable alternative for politicians and citizens who want to help improve the lives of persons who struggle to access health care. This dissertation reviews the political history of community health centers from their founding as part of the War on Poverty in the 1960s through Democratic …

Epigenomics-Based Approaches To Predict Transcriptional Regulators, Zeyu Lu

Statistical Science Theses and Dissertations

Transcriptional regulators (TRs), proteins controlling gene expression, play a critical role in health and disease. Dysregulated TRs have been implicated in various diseases and cancers, driving the development of computational methods using next-generation sequencing (NGS) data for TR identification. However, a systematic evaluation of these NGS-based methods has been lacking. This dissertation presents a comprehensive review of thirteen existing methods, benchmarking their performance using gene sets derived from TR perturbations.

We further address the emerging challenge of identifying TRs from epigenomic regions (peaks) using NGS techniques. Existing methods often rely on motif-based analysis or user-provided gene lists, both having severe …

Bat Cutaneous Microbial Assemblage Functional Redundancy Across A Host-Mediated Disturbance, Matthew Grisnik, Donald M. Walker

Biology

Understanding the processes and factors that influence the structure of host-associated microbial assemblages has been a major area of research as these assemblages play a role in host defense against pathogens. Previous work has found that bacterial taxa within bat cutaneous microbial assemblages have antifungal capabilities against the emerging fungal pathogen, Pseudogymnoascus destructans. However, our understanding of natural fluctuations in these cutaneous microbial assemblages over time due to shifts in host habitat is lacking. The objective of this work was to understand how the taxonomic and functional bat cutaneous microbial assemblage responds to seasonal shifts in host habitat. We hypothesized …

Global, Regional, And National Progress Towards The 2030 Global Nutrition Targets And Forecasts To 2050: A Systematic Analysis For The Global Burden Of Disease Study 2021, Michael Benjamin Arndt, Aleksandr Y. Aravkin, Natalia V. Bhattacharjee, Julian Chalek

Open Access archive

Background: The six global nutrition targets (GNTs) related to low birthweight, exclusive breastfeeding, child growth (ie, wasting, stunting, and overweight), and anaemia among females of reproductive age were chosen by the World Health Assembly in 2012 as key indicators of maternal and child health, but there has yet to be a comprehensive report on progress for the period 2012 to 2021. We aimed to evaluate levels, trends, and observed-to-expected progress in prevalence and attributable burden from 2012 to 2021, with prevalence projections to 2050, in 204 countries and territories. Methods: The prevalence and attributable burden of each target indicator were …

The Fourth Week Of Advent: Printable Coloring Activities, University Of Dayton. Marian Library

Marian Library Blog Archive

You and your family and friends will love these coloring sheets and printable ornament craft.

Sixth Joint Disclosure Statement

Catholic Dioceses in Bankruptcy

No abstract provided.

Measuring And Improving Api Usability And Quality: A Comprehensive Framework And Empirical Study, Sultan Alanazy

Computer Science and Engineering Theses and Dissertations

Cloud computing provides on-demand access to flexible computing resources, enabling rapid application deployment without substantial infrastructure investment. Application Programming Interfaces (APIs) play an important role in ensuring the success of cloud applications. The primary users of APIs are the extensive community of application programmers who search, read, and understand APIs before integrating them into their applications or systems. In addition, developers often turn to online API support when seeking help. Problems in such support can result in incorrect API usage and integration problems. There is an urgent need to measure API usability and support issues to identify, characterize, and assess …

Microwell Fabrication For Impedance And Ac Measurements Of Isolated Ventricular Cardiomyocytes, Fallon Wenck

Multidisciplinary Studies Theses and Dissertations

Electrophysiological behavior of human hearts have been extensively studied for hundreds of years. Even with elucidation of not just biological function, but also time and frequency-dependent current flow, the sheer intricacy of in vivo cardiac tissue function remains somewhat enigmatic. All while heart disease has been the leading cause of death in the United States for over a century, with its rates of occurrence still increasing annually [1]. Thus, new research techniques and tools to quantify cardiac function are still being pursued at smaller and smaller scales to decrease research/innovation time, cost, and diagnostic ambiguity. In fact, it remains incredibly …

From The Alhambra To The Grammar Of Ornament: Materiality And Process In The Work Of Owen Jones, Rebecca Kendall

Art History Theses and Dissertations

Much of the growing scholarship regarding the once well-known nineteenth century architect, designer, printer, and design theorist Owen Jones (1807-1874) mentions one or both of his landmark publications, Plans, Elevations, Sections and Details of the Alhambra (1836-1845) or the Grammar of Ornament (1856), occasionally noting chromolithographic innovations made at their respective times of publication. However, scholars have not really looked at the physical manufacture of these influential books by Jones and how this printing process drives the project of translation from the Alhambra. The materials surrounding Jones, whether books in his library, the pencil or brush he holds or the …

Space Tech Hub Signs First Partnership, Unh Communications And Public Affairs

UNH Today Archive

No abstract provided.

Is Functional Training Functional? A Systematic Review Of Its Effects In Community-Dwelling Older Adults, Chiung-Ju Liu, Wen-Pin Chang, Yun Chan Shin, Yi-Ling Hu, Jane Morgan-Daniel

Occupational Therapy Faculty Publications

Background: Age-related decline in physical and cognitive capacity increases older adults' risk of disability, long-term care placement, and mortality rate. Functional training, which uses activities of daily living or simulated movements to complete activities as the intervention medium, could be more effective than rote exercise, which uses repetitive movements without added purpose, in preventing late-life disability in older people. With a growing number of studies in this area, systematically studying the effect of functional training is needed. The purpose of this systematic review was to examine the effects of functional training on the outcomes of activities of daily living, physical …

Longtime Medical Center Faculty Member Creates Endowment, Bill Dabney

University of Mississippi News

OXFORD, Miss. – A longtime employee of the University of Mississippi Medical Center hopes a scholarship he and his wife established will help relieve financial burdens faced by many medical students while also supporting those who recruit new med school candidates.

Ruth Marie Hobbs

African American Funeral Programs

Ruth_Marie_Hobbs.pdf - Funeral program for Ruth Marie Hobbs

Adapting Weighted Gene Co-Expression Network Analysis For Next Generation Sequencing, Molly Robinson

Mathematics Theses and Dissertations

New technologies such as single-cell RNA-sequencing (scRNA-seq) have become vital to the understanding of cell type heterogeneity. One limitation of this technique is that the resulting data sets are sparse. That is, genes often have read counts of zero in a given cell. Computational challenges arise when sparse data sets are analyzed with Weighted Gene Co-Expression Network Analysis (WGCNA), a technique that has been used to study the underlying genetic network of bulk data sets.

This project aims to study how sparsity degrades the performance of WGCNA. This is done by modifying data sets where the method has been successfully …

Extraordinary 21st Century Drought In The Po River Basin (Italy), Abel Andrés Ramírez Molina, Glenn Tootle, Giuseppe Formetta, Thomas Piechota, Jiaqi Gong

Biology, Chemistry, and Environmental Sciences Faculty Articles and Research

Recent research identified 2022 as being the year of lowest seasonal April–May–June–July (AMJJ) observed streamflow for the Po River Basin (PRB) in the past two centuries. Expanding upon this research, we applied filters (2-year to 30-year filters) to the AMJJ observed streamflow and identified the late 20th and 21st century as displaying extreme drought. In this study, we introduce PALEO-RECON, an automated reconstruction tool developed to leverage tree ring-based proxies and streamline regression processes. Using PALEO-RECON, we reconstructed the AMJJ streamflow, applying traditional regression techniques and using a nested approach in which 30-, 40-, and 50-year windows within the ~200-year …

Complexities, Benefits, Risks, And Clinical Implications Of Sodium Bicarbonate Administration In Critically Ill Patients: A State-Of-The-Art Review, Akram M. Eraky, Yashwanth Yerramalla, Adnan Khan, Yasser Mokhtar, Alisha Wright, Walaa Alsabbagh, Kevin Franco Valle, Mina Haleem, Kyle Kennedy, Chad Boulware

GME Publications

Sodium bicarbonate has been used in the treatment of different pathologies, such as hyperkalemia, cardiac arrest, tricyclic antidepressant toxicity, aspirin toxicity, acute acidosis, lactic acidosis, diabetic ketoacidosis, rhabdomyolysis, and adrenergic receptors' resistance to catecholamine in patients with shock. An ongoing debate about bicarbonate's efficacy and potential harm has been raised for decades because of the lack of evidence supporting its potential efficacy. Despite the guidelines' restrictions, sodium bicarbonate has been overused in clinical practice. The overuse of sodium bicarbonate could be because of the desire to correct the arterial blood gas parameters rapidly instead of achieving homeostasis by treating the …

Analyzing Handwriting Legibility In Children Using Smart Vs. Traditional Pen, Franceli L. Cibrian, Lauren Min, Yingying 'Yuki' Chen, Kayla Anderson, Oscar Gutierrez, Lizbeth Escobedo

Engineering Faculty Articles and Research

Handwriting, traditionally acquired through paper, pen, or pencil, is crucial for children’s development, learning, and communication. The legibility of letters holds crucial implications for children’s composition and even self-esteem. In order to ensure legibility, timely input from educators and parents is essential, although it primarily depends on their experience. With current technological advancements, smartpens, augmented with sensing capabilities, could offer a novel approach providing feedback. However, it is unclear if the smartpen’s weight and form factor could affect children’s handwriting legibility is unclearsmartpen’s weight and form factor could affect children’s handwriting legibility. This study involves 16 children aged 9 to …

Towards A Multimodal Approach For Assessing Adhd Hyperactivity Behaviors, Franceli L. Cibrian, Lauren Min, Vitica Arnold

Engineering Faculty Articles and Research

Attention Deficit Hyperactivity Disorder (ADHD) is the most prevalent childhood psychiatric condition that needs an assessment of inattention, hyperactivity, and impulsiveness symptoms. Particularly in young children, hyperactivity-impulsivity stands out as a primary concern. However, those behaviors may or may not be evidenced when a child is in a small room, one-on-one with a single adult. Therefore, Ambient Intelligence technology that supports data collection in a natural setting, paired with expert human decision-making can potentially improve the quality of assessments. In this paper, we conduct a literature review and analysis to align ADHD assessment criteria with potential sensor technologies to collect …

The International Bathymetric Chart Of The Arctic Ocean Version 5.0, Martin Jakobsson, Rezwan Mohammad, Marcus Karlsson, Silvia Salas-Romero, Florian Vacek, Florian Heinze, Caroline Bringensparr, Carlos F. Castro, Juliet Kinney, Sara Cardigos, Michael Bogonko, Daniela Accettella, David Amblas, Lu An, Aileen Bohan, Angelika Brandt, Stefan Bunz, Miquel Canals, José Luis Casamor, Bernard Coakley, Natalie Cornish, Seth Danielson, Maurizio Demarte, Davide Di Franco, Mary-Lynn Dickson, Boris Dorschel, Julian A. Dowdeswell, Simon Dreutter, Alice C. Fremand, John K. Hall, Bryan Hally, David Holland, Jon Kuk Hong, Roberta Ivaldi, Paul C. Knutz, Diana W. Krawczyk, Yngve Kristofferson, Galderic Lastras, Caroline Leck, Renata G. Lucchi, Giuseppe Masetti, Mathieu Morlighem, Julia Muchowski, Tove Nielsen, Riko Noormets, Andreia Plaza-Faverola, Megan M. Prescott, Autun Purser, Tine L. Rasmussen, Michele Rebesco, Eric Rignot, Søren Rysgaard, Anna Silyakova, Pauline Snoeijs-Leijonmalm, Aqqaluk Sørensen, Fiammetta Straneo, David A. Sutherland, Alex J. Tate, Paola Travaglini, Nicole Trenholm, Esmee Van Wijk, Luke Wallace, Josh K. Willis, Michael Wood, Mark Zimmermann, Karl B. Zinglersen, Larry A. Mayer

Center for Coastal and Ocean Mapping

Knowledge about seafloor depth, or bathymetry, is crucial for various marine activities, including scientific research, offshore industry, safety of navigation, and ocean exploration. Mapping the central Arctic Ocean is challenging due to the presence of perennial sea ice, which limits data collection to icebreakers, submarines, and drifting ice stations. The International Bathymetric Chart of the Arctic Ocean (IBCAO) was initiated in 1997 with the goal of updating the Arctic Ocean bathymetric portrayal. The project team has since released four versions, each improving resolution and accuracy. Here, we present IBCAO Version 5.0, which offers a resolution four times as high as …

Inhibition Of Microrna-660-5p Decreases Breast Cancer Progression Through Direct Targeting Of Tmem41b, Valeria Villarreal-García, José Roberto Estupiñan-Jiménez, Vianey Gonzalez-Villasana, Pablo E Vivas-Mejía, Marienid Flores-Colón, Irma Estefanía Ancira-Moreno, Patricio Adrián Zapata-Morín, Claudia Altamirano-Torres, José Manuel Vázquez-Guillen, Cristina Rodríguez-Padilla, Recep Bayraktar, Mohamed H Rashed, Cristina Ivan, Gabriel Lopez-Berestein, Diana Reséndez-Pérez

Faculty, Staff and Student Publications

Background: Breast cancer is the most prevalent cancer among women worldwide. Most breast cancer-related deaths result from metastasis and drug resistance. Novel therapies are imperative for targeting metastatic and drug-resistant breast cancer cells. Accumulating evidence suggests that dysregulated microRNAs (miRNAs) promote breast cancer progression, metastasis, and drug resistance. Compared with healthy breast tissue, miR-660-5p is notably overexpressed in breast cancer tumor tissues. However, the downstream effectors of miR-660-5p in breast cancer cells have not been fully elucidated. Our aim was to investigate the role of miR-660-5p in breast cancer cell proliferation, migration, invasion, and angiogenesis and to identify its potential …

Microbubble-Protected Oncolytic Virotherapy Targeted By Sonoporation Induces Tumor Necrosis And T-Lymphocyte Infiltration In Humanized Mice Bearing Triple-Negative Breast Cancer, Juliana Sitta, Flavia De Carlo, Imani Kirven, John H. Tackett, Patrice Penfornis, George Clement Dobbins, Mallory Barbier, Luis Del Valle, Clayton T. Larsen, Ernest G. Schutt, Rhodemann Li, Candace M. Howard, Pier Paolo Claudio

School of Medicine Faculty Publications

Oncolytic virotherapy has shown great promise in mediating targeted tumor destruction through tumor-selective replication and induction of anti-tumor immunity; however, obstacles remain for virus candidates to reach the clinic. These include avoiding neutralizing antibodies, preventing stimulation of the adaptive immune response during intravenous administration, and inducing sufficient apoptosis and immune activation so that the body's defense can work to eradicate systemic disease. We have developed a co-formulation of oncolytic viruses (OVs) with Imagent lipid-encapsulated, perfluorocarbon microbubbles (MBs) to protect the OVs from the innate and adaptive immune system. Once inside the MB, the viral particles become acoustically active such that …

Summed Series Involving 1F2 Hypergeometric Functions, Jack C. Straton

Physics Faculty Publications and Presentations

Summation of infinite series has played a significant role in a broad range of problems in the physical sciences and is of interest in a purely mathematical context. In a prior paper, we found that the Fourier–Legendre series of a Bessel function of the first kind J_N(kx) and modified Bessel functions of the first kind I_N(kx) lead to an infinite set of series involving ₁F₂ hypergeometric functions (extracted therefrom) that could be summed, having values that are inverse powers of the eight primes 1/ ( 2ⁱ 3^j 5^{k …}

International Workshop: What Is Needed To Ensure Outcome Measures For Rett Syndrome Are Fit-For-Purpose For Clinical Trials? June 7, 2023, Nashville, Usa, Jenny Downs, Dominique C Pichard, Walter E Kaufmann, Joseph P Horrigan, Melissa Raspa, Gillian Townend, Eric D Marsh, Helen Leonard, Kathleen Motil, Andrew C Dietz, Nupur Garg, Amitha Ananth, Breanne Byiers, Sarika Peters, Christopher Beatty, Frank Symons, Aleksandra Jacobs, James Youakim, Bernhard Suter, Paramola Santosh, Jeffrey L Neul, Tim A Benke

Faculty, Staff and Students Publications

INTRODUCTION: The clinical, research and advocacy communities for Rett syndrome are striving to achieve clinical trial readiness, including having fit-for-purpose clinical outcome assessments. This study aimed to (1) describe psychometric properties of clinical outcome assessment for Rett syndrome and (2) identify what is needed to ensure that fit-for-purpose clinical outcome assessments are available for clinical trials.

METHODS: Clinical outcome assessments for the top 10 priority domains identified in the Voice of the Patient Report for Rett syndrome were compiled and available psychometric data were extracted. The clinical outcome assessments measured clinical severity, functional abilities, comorbidities and quality of life, and …

Phenotypic And Genetic Heterogeneity Of A Pakistani Cohort Of 15 Consanguineous Families Segregating Variants In Leber Congenital Amaurosis-Associated Genes, Zainab Akhtar, Sumaira Altaf, Yumei Li, Sana Bibi, Jamal Shah, Kiran Afshan, Meng Wang, Hafiz Muhammad Jafar Hussain, Nadeem Qureshi, Rui Chen, Sabika Firasat

Faculty, Staff and Students Publications

Background: Leber congenital amaurosis (LCA) is a congenital onset severe form of inherited retinal dystrophy (IRD) and a common cause of pediatric blindness. Disease-causing variants in at least 14 genes are reported to predispose LCA phenotype. LCA is inherited as an autosomal recessive disease. It can be an isolated eye disorder or as part of a syndrome, such as Senior Loken or Joubert syndrome. Sequencing studies from consanguineous populations have proven useful for novel variants identification; thus, the present study aimed to explore the genetic heterogeneity of 15 consanguineous Pakistani families, each segregating a severe IRD phenotype using targeted next …

Relative Survival, Conditional Survival, And Causes Of Death In Patients With Early Gastric Cancer, With A Focus On Differences Between Cardia And Non-Cardia Cancer, Anas Elgenidy, Omar Alomari, Mohamed Marey Hesn, Anas Khaled, Sarah A Nada, Mostafa Elsayed, Ali Mahmoud, Mohammed Al-Mahdi Al-Kurdi, Ahmed M Afifi, George Cholankeril

Faculty, Staff and Students Publications

Background: Many researchers believe that cardia (CGC) and non-cardia (NCGC) are two different types of tumors, having different features like incidence rate, risk factors, geographical location, and socioeconomic status. This study aims to investigate the causes of death (COD) survival rates among early gastric cancer patients with a focus on differences between CGC and NCGC.

Methods: This retrospective study employed SEER*stat software (version 8.3.92) to analyze the SEER 17 plus dataset (2000–2019). Standardized mortality ratios (SMR) were computed. Relative survival and conditional survival post-diagnosis were calculated using R software (version 4.1.0) among the different subgroups.

Results: Within the follow-up period, …

Parallel Circles: A Math Club As A University Math Circle, Sarah C. Cobb, Marcos Lopez

Journal of Math Circles

This paper will discuss a monthly social event for the University Math Club. Over the past several years, the event has been shaped by the philosophy of a Student Math Circle. We will discuss the event's organization and the ways it has benefited from the influence of the Math Circle community.

Music In Medieval Rituals For The End Of Life, Karl Isaac Johnson

Yale Journal of Music & Religion

A book review is presented for Music in Medieval Rituals for the End of Life, authored by Elaine Stratton Hild, by Karl Isaac Johnson.