Digital Commons Network^™

Improved Adherence To Lipid Screening In The Pediatric Cardiology Clinic: A Quality Improvement Project, Rachel Magnan, Thomas Murphy, Lauren Rosenthal, Aparna Prasad, Anjali Chelliah, Stuart Kaufman, Donna Timchak, Lindsey Mcphillips, Saira Siddiqui

Department of Pediatrics Faculty Papers

INTRODUCTION: Lipid screening identifies at-risk patients to facilitate cardiovascular risk reduction. National pediatric guidelines recommend universal lipid screening between 9-11 and 17-21 years of age. We aimed to improve adherence to lipid screening for all age-appropriate outpatient pediatric cardiology visits from a baseline of 35% to 90% between November 2021 and July 2023.

METHODS: All outpatient visits for patients 9-11 and 17-21 years were included. Chart review and an Epic electronic health record report identified patients screened, lipid test results, and need for further testing. A P-chart was generated. After establishing a baseline for 8 weeks, interventions, including an Epic …

From The Ocean To Our Kitchen Table: Anthropogenic Particles In The Edible Tissue Of U.S.. West Coast Seafood Species, Summer D. Traylor, Elise F. Granek, Marilyn Duncan, Susanne Brander

Environmental Science and Management Faculty Publications and Presentations

Microplastics (MPs) and other anthropogenic particles (APs) are pervasive environmental contaminants found throughout marine and aquatic environments. We quantified APs in the edible tissue of black rockfish, lingcod, Chinook salmon, Pacific herring, Pacific lamprey, and pink shrimp, comparing AP burdens across trophic levels and between vessel-retrieved and retail-purchased individuals. Edible tissue was digested and analyzed under a microscope, and a subset of suspected APs was identified using spectroscopy (μFTIR). Anthropogenic particles were found in 180 of 182 individuals. Finfish contained 0.02–1.08 AP/g of muscle tissue. In pink shrimp (Pandalus jordani), the average AP/g was 10.68 for vessel-retrieved and …

Special Education Co-Teachers’ Role In The Adoption Of Information And Communication Technology Tools In Inclusive Classrooms, Amy Hysick

Walden Dissertations and Doctoral Studies

Co-teaching is a common service delivery model where a general and special education teacher are paired in the same classroom, though little is known about the experiences of secondary special education co-teachers in the adoption and use of information and communication technology (ICT) tools in inclusive, co-taught classrooms. The purpose of this qualitative study was to investigate the experiences of special education co-teachers in the adoption and use of ICT tools. Venkatesh et al.’s unified theory of the acceptance and use of technology was the conceptual framework for the study. The research question focused on the experiences of special education …

Perceptions Of Black Women’S Portraits Of Beauty In Essence Magazine, Dr. Rachel Mingo

Walden Dissertations and Doctoral Studies

Historically, beauty standards in the United States were rooted in White ideals, influencing media portrayals of Black women to align with White features like lighter skin and straightened hair. Although recent studies suggest a slow shift toward a more diverse representation of Black beauty, depictions in magazines still predominantly reflect mainstream Western beauty ideals, leading to potential negative impacts on Black women’s self-esteem and body image. The purpose of this generic qualitative study was to explore how young Black women, ages 18–25, perceive portrayals of Black beauty in Essence magazine. Black feminist thought constituted the theoretical basis for this study. …

New Graduate Nurses' Experiences Of Burnout As They Transition To Practice, Stacy Beth Elliott

Walden Dissertations and Doctoral Studies

Transitioning from nursing school to professional practice is a critical and challenging period for newly graduated nurses. Transition to professional nursing practice is particularly stressful in the first 3 years as new graduates adapt to the high acuity of patient care, which can result in burnout. The purpose of this qualitative study, guided by the conservation of resource theory, was to understand how new graduate nurses describe their experiences of burnout as novice nurses transition in the first 3 years of nursing practice. Fourteen nurses were interviewed using a semi-structured interviews, and Saldana’s two-cycle analysis was used for data interpretation, …

Hiring, Training, And Retaining Mental Health Professionals At Rural Wisconsin Correctional Facilities, Jessica Kallenbach

Walden Dissertations and Doctoral Studies

Correctional facilities in rural Wisconsin have noted a shortage of trained mental health professionals to provide care. Common barriers to providing mental health services in rural areas are the availability and accessibility of mental health professionals. Due to limited access to financial and career benefits, mental health professionals tend to avoid working in these areas. The purpose of this qualitative phenomenological study was to explore the lived experience of mental health professionals, administrators, and supervisors in hiring, training, and retaining staff in rural Wisconsin correctional facilities. Bandura’s social learning theory was used to guide the study. Data was collected from …

Tacrolimus- And Mycophenolate-Mediated Toxicity: Clinical Considerations And Options In Management Of Post-Transplant Patients, Alan D. Kaye, Shivam S. Shah, Coplen D. Johnson, Adalyn S. De Witt, Austin S. Thomassen, Charles P. Daniel, Shahab Ahmadzadeh, Sridhar Tirumala, Kristin N. Bembenick, Adam M. Kaye, Sahar Shekoohi

Pacific Faculty Work

Tacrolimus and mycophenolate are important immunosuppressive agents used to prevent organ rejection in post-transplant patients. While highly effective, their use is associated with significant toxicity, requiring careful management. Tacrolimus, a calcineurin inhibitor, is linked to nephrotoxicity, neurotoxicity, metabolic disturbances such as diabetes mellitus and dyslipidemia, and cardiovascular complications such as hypertension and arrhythmias. Mycophenolate, a reversible inhibitor of inosine monophosphate dehydrogenase, frequently causes gastrointestinal disturbances, including diarrhea and colitis, as well as hematologic side effects like anemia and leukopenia, which increase infection risk. Therapeutic drug monitoring (TDM) and pharmacogenomics have emerged as essential strategies for mitigating these toxicities. TDM ensures …

Geneseo Authors Celebration 2024, Milne Library

Geneseo Authors Celebration

Milne Library began a tradition of celebrating faculty authorship in 2009 with a series of workshops and a celebration in collaboration with the Teaching and Learning Center. Over the years it has evolved to more accurately reflect on the variety of academic and creative work done here at Geneseo. The annual Geneseo Authors Celebration is an opportunity for the Library and the campus to celebrate the faculty and truly acknowledge the time and effort that faculty have invested into creating exceptional works that contribute to the scholarly discussions taking place in their disciplines.

In late fall 2024, when the Geneseo …

Loss Of Chop Prevents Joint Degeneration And Pain In A Mouse Model Of Pseudoachondroplasia, Jacqueline T Hecht, Alka C Veerisetty, Mohammad G Hossain, Debabrata Patra, Michele Carrer, Frankie Chiu, Dorde Relic, Paymaan Jafar-Nejad, Karen L Posey

Faculty, Staff and Student Publications

Pseudoachondroplasia (PSACH), a severe dwarfing condition characterized by impaired skeletal growth and early joint degeneration, results from mutations in cartilage oligomeric matrix protein (COMP). These mutations disrupt normal protein folding, leading to the accumulation of misfolded COMP in chondrocytes. The MT-COMP mouse is a murine model of PSACH that expresses D469del human COMP in response to doxycycline and replicates the PSACH chondrocyte and clinical pathology. The basis for the mutant-COMP pathology involves endoplasmic reticulum (ER) stress signaling through the PERK/eIF2α/CHOP pathway. C/EBP homologous protein (CHOP), in conjunction with a TNFα inflammatory process, upregulates mTORC1, hindering autophagy clearance of mutant COMP …

Population-Based Study Of The Epidemiology Of Stiff Person Syndrome In A Large Colorado-Based Health System, Paul Daniel Crane, Stefan Sillau, Renee Dreher, Rikki Fix, Phillip Winters, Russell Van Coevering, Eric Engebretson, Brooke Valdez, Elizabeth Matthews, Kavita V. Nair, Aaron M. Carlson, Amanda L. Piquet

Student Publications

Background and objectives: Stiff person syndrome spectrum disorder (SPSD) is a rare autoimmune disorder characterized by progressive muscle stiffness and painful spasms with an estimated prevalence of 1-2 cases per million people. Population-based epidemiologic studies are lacking because of both poor patient capture and the lack of standardized diagnostic criteria. Objectives of this study were to describe the incidence and prevalence of SPSD within the University of Colorado Health (UCH) system and apply previously proposed published criteria for SPSD within this population.

Methods: We queried Health Data Compass, an electronic health data repository for a large academic health care system, …

Epithelial Barrier Hypothesis: A Systematic Review, Krishna Patel, Peter Lio

Student Publications

Background

The epithelial barriers, which include the skin, the gut, and the respiratory lining, play a crucial role in protecting the body from pathogens and environmental threats. Many harmful toxins are increasingly part of modern life. The increase in usage of these damaging agents in conjunction with the increase in allergic inflammatory conditions suggests that the “epithelial barrier hypothesis”—the concept that damage to the epithelia by external agents can result in dysbiosis, inflammation, and allergy—may explain the rise in these conditions seen in the developed world.

Objective

We sought to assess the evidence for the epithelial barrier hypothesis, with particular …

Perceptions Of Black Women’S Portraits Of Beauty In Essence Magazine, Dr. Rachel Mingo

Walden Dissertations and Doctoral Studies

Historically, beauty standards in the United States were rooted in White ideals, influencing media portrayals of Black women to align with White features like lighter skin and straightened hair. Although recent studies suggest a slow shift toward a more diverse representation of Black beauty, depictions in magazines still predominantly reflect mainstream Western beauty ideals, leading to potential negative impacts on Black women’s self-esteem and body image. The purpose of this generic qualitative study was to explore how young Black women, ages 18–25, perceive portrayals of Black beauty in Essence magazine. Black feminist thought constituted the theoretical basis for this study. …

New Graduate Nurses' Experiences Of Burnout As They Transition To Practice, Stacy Beth Elliott

Walden Dissertations and Doctoral Studies

Transitioning from nursing school to professional practice is a critical and challenging period for newly graduated nurses. Transition to professional nursing practice is particularly stressful in the first 3 years as new graduates adapt to the high acuity of patient care, which can result in burnout. The purpose of this qualitative study, guided by the conservation of resource theory, was to understand how new graduate nurses describe their experiences of burnout as novice nurses transition in the first 3 years of nursing practice. Fourteen nurses were interviewed using a semi-structured interviews, and Saldana’s two-cycle analysis was used for data interpretation, …

Hiring, Training, And Retaining Mental Health Professionals At Rural Wisconsin Correctional Facilities, Jessica Kallenbach

Walden Dissertations and Doctoral Studies

Correctional facilities in rural Wisconsin have noted a shortage of trained mental health professionals to provide care. Common barriers to providing mental health services in rural areas are the availability and accessibility of mental health professionals. Due to limited access to financial and career benefits, mental health professionals tend to avoid working in these areas. The purpose of this qualitative phenomenological study was to explore the lived experience of mental health professionals, administrators, and supervisors in hiring, training, and retaining staff in rural Wisconsin correctional facilities. Bandura’s social learning theory was used to guide the study. Data was collected from …

Targeted Degradation Of Oncogenic Krasg12v Triggers Antitumor Immunity In Lung Cancer Models, Dezhi Li, Ke Geng, Yuan Hao, Jiajia Gu, Saurav Kumar, Annabel T Olson, Christina C Kuismi, Hye Mi Kim, Yuanwang Pan, Fiona Sherman, Asia M Williams, Yiting Li, Fei Li, Ting Chen, Cassandra Thakurdin, Michela Ranieri, Mary Meynardie, Daniel S Levin, Janaye Stephens, Alison Chafitz, Joy Chen, Mia S Donald-Paladino, Jaylen M Powell, Ze-Yan Zhang, Wei Chen, Magdalena Ploszaj, Han Han, Shengqing Stan Gu, Tinghu Zhang, Baoli Hu, Benjamin A Nacev, Medard Ernest Kaiza, Alice H Berger, Xuerui Wang, Jing Li, Xuejiao Sun, Yang Liu, Xiaoyang Zhang, Tullia C Bruno, Nathanael S Gray, Behnam Nabet, Kwok-Kin Wong, Hua Zhang

Faculty, Staff and Student Publications

Kirsten rat sarcoma viral oncogene homolog (KRAS) is the most frequently mutated oncogene in lung adenocarcinoma, with G12C and G12V being the most predominant forms. Recent breakthroughs in KRASG12C inhibitors have transformed the clinical management of patients with the G12C mutation and advanced our understanding of the function of this mutation. However, little is known about the targeted disruption of KRASG12V, partly due to a lack of specific inhibitors. Here, we leverage the degradation tag (dTAG) system to develop a KRASG12V-transgenic mouse model. We explored the therapeutic potential of KRASG12V degradation and characterized its effect on the tumor microenvironment (TME). …

Generative Ai In Shariah Advisory In Islamic Finance: An Experimental Study, Muhammad Noman Jokhio, Muhammad Asif Jaffer

Business Review

Islamic banks adhere strictly to Shariah principles in all operations and offerings, creating a demand for experts proficient in Shariah-compliant banking and finance. This study investigates the potential of using generative AI, specifically Large Language Models (LLMs), to provide Shariah advisory in complex Islamic financing scenarios. The research evaluates general purpose public LLMs—such as ChatGPT, Gemini, and Meta AI—on their ability to identify Shariah compliance issues, cite relevant Shariah references, and propose actionable guidance for resolving compliance challenges in complex Islamic financing scenarios. A qualitative approach was used. The experimental study involved creation of complex, realistic financing scenarios requiring Shariah …

Muqarnas In Damascus: A Forgotten Treasure’S History, Inception And Geometry, Nahed Jawad Chakouf

All Works

The architecture of the Islamic world encompasses both religious and secular buildings that are unified by the use of a common architectural language, which includes architectural elements such as minarets, domes and arches, ornamental details, and vaulting with the use of muqarnas. The study provides a broad overview of the development of Islamic architecture, focusing on Damascus, the early Islamic period, the mid-Islamic period and the late Islamic period. The late Islamic period includes Ottoman art, with architecture influenced by Byzantine, Persian, Armenian, and Mamluk artefacts, but differs from their predecessors. The researcher undertook a geometric analysis of the muqarnas …

Non(Belonging) Of Ethnic Minority Communities In Britain: Researcher Reflections, Suparna Bagchi

School of Law, Humanities and Social Sciences

Introduction. There is limited research concerning the experiences of people belonging to ethnic minority communities in predominantly White places (Cline et al., 2002; Garland & Chakraborti, 2006; Scourfield & Davies, 2005). Predominantly White places are those that are inhabited by people from ethnic minority communities with restricted communication with places of worship, cultural institutions and educational norms of their communities, for which they do not feel included (DfES, 2004). In these places, these people not only reside in an invisible state (Bhopal, 2014), but their voices also stay unheard (Chakraborti & Garland, 2004) in official records (Pac-Soo & Taylor, 2023). …

Effects Of Bilingual Language Exposure On Toddlers With Autism Spectrum Disorder, Sarah Phillips, Amelia Yanchik, Heather Jung, Peter Vietze, Leah Esther Lax

Department of Psychology Faculty Scholarship and Creative Works

Research analyzing the effects of bilingual language exposure on children with autism spectrum disorder (ASD) has increased in frequency. Utilizing the Bayley Scales of Infant and Toddler Development—Third Edition, the current study analyzed the effects of bilingual language exposure and age on language development, cognitive development, and social emotional development in toddlers with ASD. Older children demonstrated higher language scores than younger children. The interaction between ASD and bilingualism did not yield statistical significance for language, cognitive, or social emotional scores; however, the interaction between age and bilingualism was found to be significant. Age may have more of an influence …

Digital Cognitive Behavioral Therapy Vs Education For Pain In Adults With Sickle Cell Disease, Charles R. Jonassaint, Christina M. Lalama, C. Patrick Carroll, Sherif M. Badawy, Megan E. Hamm, Jennifer N. Stinson, Chitra Lalloo, Santosh L. Saraf, Victor R. Gordeuk, Robert M. Cronin, Nirmish Shah, Sophie M. Lanzkron, Darla Liles, Julia A. O'Brien, Cassandra Trimnell, Lakiea Bailey, Raymona H. Lawrence, Leshana Saint Jean, Michael Debaun, Laura M. De Castro, Tonya M. Palermo, Kaleab Z. Abebe

Department of Medicine Faculty Papers

Despite the burden of chronic pain in sickle cell disease (SCD), nonpharmacological approaches remain limited. This multisite, randomized trial compared digital cognitive behavioral therapy (CBT) with a digital pain/SCD education program ("Education") for managing pain and related symptoms. Participants were recruited virtually from seven SCD centers and community organizations in the United States. Adults (aged ≥18 years) with SCD-related chronic pain and/or daily opioid use were assigned to receive either CBT or Education for 12 weeks. Both groups used an app with interactive chatbot lessons and received personalized health coach support. The primary outcome was the change in pain interference …

Loss Of Chop Prevents Joint Degeneration And Pain In A Mouse Model Of Pseudoachondroplasia, Jacqueline T Hecht, Alka C Veerisetty, Mohammad G Hossain, Debabrata Patra, Michele Carrer, Frankie Chiu, Dorde Relic, Paymaan Jafar-Nejad, Karen L Posey

2020-Current year OA Pubs

Pseudoachondroplasia (PSACH), a severe dwarfing condition characterized by impaired skeletal growth and early joint degeneration, results from mutations in cartilage oligomeric matrix protein (COMP). These mutations disrupt normal protein folding, leading to the accumulation of misfolded COMP in chondrocytes. The MT-COMP mouse is a murine model of PSACH that expresses D469del human COMP in response to doxycycline and replicates the PSACH chondrocyte and clinical pathology. The basis for the mutant-COMP pathology involves endoplasmic reticulum (ER) stress signaling through the PERK/eIF2α/CHOP pathway. C/EBP homologous protein (CHOP), in conjunction with a TNFα inflammatory process, upregulates mTORC1, hindering autophagy clearance of mutant COMP …

Nonprofit Spotlight: Choice Humanitarian, Erica Jensen

Journal of Nonprofit Innovation

No abstract provided.

Research Summaries: Access To Education, Erica Jensen

Journal of Nonprofit Innovation

No abstract provided.

Full Issue: Access To Education, Angie Holzer

Journal of Nonprofit Innovation

No abstract provided.

Public Disclosure And Its Impact On Ceo Compensation: Evidence Of Media Influence, Xin Zhao

Journal of Global Awareness

I examine the effect of the AFL-CIO executive paywatch identification on future CEO compensation. My findings indicate that the public disclosure of CEO compensation has a negative impact on subsequent changes in CEO pay. Additionally, I find that CEOs with ex-ante overpayment have experienced changes in their subsequent compensation. This paper contributes to the literature by documenting that firms respond to negative press coverage of CEO compensation, even after controlling for the mean reversion effect associated with high CEO pay.

Effects Of Monetary Policy On Economic Growth: Evidence From Some Developing And Developed Economies, Collins Anosike

Journal of Global Awareness

The study examined the effects of monetary policy on the economic growth of some developing and developed economies. This study selected 33 countries grouped into 11 each as first-group, second-group, and third-group countries and showed how monetary policy has influenced their economic growth in the past 40 years, capturing the economic growth performances before and after the global financial crisis. This study is unique because it captures a broader range of countries compared to previous studies, uses updated data, and shows how monetary policy is transmitted through bank lending and financial intermediation. Furthermore, we use panel data and employ fixed …

Assessing State Laws And Regulations On Radon In Us Childcare Centers, Benjamin Poku, Sayed Hussaini

Journal of Global Awareness

In the US, radon is the second most significant contributor to lung cancer, following smoking. Despite this, there is a notable absence of state-level measures and guidelines aimed at managing and mitigating the risks associated with exposure to radon gas. The objective of this research was to investigate whether state-level laws regarding radon in childcare centers have a correlation with the proportion of counties in each state that fall under radon zone 1 (with levels exceeding 4 pCi/L). The research method was secondary analysis. Data was gathered from multiple sources, including the EPA radon website, academic journals, official state government …

Takaful Insurance Industries In Supporting Sustainable Socio-Economic Development In Indonesia, Fera Widyanata, Rasyida Pertiwi, Ahmad Syathiri

Journal of Global Awareness

Over the past four years, the demand for Takaful (Islamic insurance) among Indonesians has risen. Health Takaful has emerged as the most popular, followed by educational Takaful. Health and education are parts of the Human Development Index (HDI) and are closely related to building a stronger foundation for Indonesia's economic development. This study aims to enhance the Islamic finance ecosystem's impact on achieving SDGs, focusing on health (SDG 3), education (SDG 4), and economic growth (SDG 8), which are crucial for Indonesia's development. It discovers a causal relationship between the takaful industry and improvements in the health sector and …

The Mediation Of Financial Behavior To Financial Literacy And Spending Habits Of Gen Z: An Exploratory Factor Analysis, Joel Mark Rodriguez, Del Carmen Labong, Lourdes Palallos

Journal of Global Awareness

The study aims to explain the relationship of financial literacy with spending habits and behavior. Financial behavior is a mediator of Generation Z. Financial literacy is a very important dimension in making financial decisions, and this research highlighted the direct and indirect impacts that financial literacy exerts on spending behavior. Data is collected from 317 respondents using a structured questionnaire measuring financial literacy, financial behavior, and spending behavior. Correlation, regression, mediation analysis, and Structural Equation Modeling have been used in evaluating these relationships. Financial literacy directly reflects a strong relationship with spending behavior, and its coefficient is 1.167. Financial behavior, …

A Study Abroad Immersion And Reflection Of American Liberal Arts Students In Cyprus, Mark Reimer, Yiannis Miralis

Journal of Global Awareness

Ensemble tours abroad, with a liberal arts focus, provide a rich, unique, and highly educational opportunity to make music while experiencing the history, people, language, and culture of another country. Pre-tour preparation, however, requires research and a trusted relationship between the director and the host to ensure that the musicians in both countries enjoy the same degree of excitement and desire to learn from one another. The following article is research that was conducted for an American college wind ensemble tour to Cyprus. In addition to reviewing several books and journals, the authors listened to hours of classical, folk, and …