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Articles 39301 - 39307 of 39307
Full-Text Articles in Entire DC Network
Identification Of Druggable Regulators Of Cell Secretion Via A Kinome-Wide Screen And High-Throughput Immunomagnetic Cell Sorting, Mahmoud Labib, Zongjie Wang, Yunhye Kim, Sichun Lin, Abdalla Abdrabou, Hanie Yousefi, Pei Ying Lo, Stéphane Angers, Edward H. Sargent, Shana O. Kelley
Identification Of Druggable Regulators Of Cell Secretion Via A Kinome-Wide Screen And High-Throughput Immunomagnetic Cell Sorting, Mahmoud Labib, Zongjie Wang, Yunhye Kim, Sichun Lin, Abdalla Abdrabou, Hanie Yousefi, Pei Ying Lo, Stéphane Angers, Edward H. Sargent, Shana O. Kelley
Peninsula Medical School
The identification of genetic regulators of cell secretions is challenging because it requires the sorting of a large number of cells according to their secretion patterns. Here we report the development and applicability of a high-throughput microfluidic method for the analysis of the secretion levels of large populations of immune cells. The method is linked with a kinome-wide loss-of-function CRISPR screen, immunomagnetically sorting the cells according to their secretion levels, and the sequencing of their genomes to identify key genetic modifiers of cell secretion. We used the method, which we validated against flow cytometry for cytokines secreted from primary mouse …
What Is The Volume, Quality And Characteristics Of Evidence Relating To The Effectiveness And Cost-Effectiveness Of Multi-Disciplinary Occupational Health Interventions Aiming To Improve Work-Related Outcomes For Employed Adults? An Evidence And Gap Map Of Systematic Reviews, Elizabeth Shaw, Michael Nunns, Stuart G. Spicer, Hassanat Lawal, Simon Briscoe, G. J. Melendez-Torres, Ruth Garside, Kristin Liabo, Jo Thompson Coon
What Is The Volume, Quality And Characteristics Of Evidence Relating To The Effectiveness And Cost-Effectiveness Of Multi-Disciplinary Occupational Health Interventions Aiming To Improve Work-Related Outcomes For Employed Adults? An Evidence And Gap Map Of Systematic Reviews, Elizabeth Shaw, Michael Nunns, Stuart G. Spicer, Hassanat Lawal, Simon Briscoe, G. J. Melendez-Torres, Ruth Garside, Kristin Liabo, Jo Thompson Coon
Peninsula Medical School
Background: In the UK, tens of millions of working days are lost due to work-related ill health every year, costing billions of pounds. The role of Occupational Health (OH) services is vital in helping workers to maintain employment when they encounter injury or illness. OH providers traditionally rely on a clinical workforce to deliver these services, particularly doctors and nurses with OH qualifications. However, the increasing demand for OH services is unlikely to be met in the future using this traditional model, due to the declining number of OH-trained doctors and nurses in the UK. Multi-disciplinary models of OH delivery, …
Avip 1023 Private Pilot Flight Training, Steelman Library
Avip 1023 Private Pilot Flight Training, Steelman Library
Syllabus Repository
No abstract provided.
Avip 2023 Instrument Flight Training, Steelman Library
Avip 2023 Instrument Flight Training, Steelman Library
Syllabus Repository
No abstract provided.
Avip 3023 Commercial Pilot Flight I Flight Training, Steelman Library
Avip 3023 Commercial Pilot Flight I Flight Training, Steelman Library
Syllabus Repository
No abstract provided.
Avip 3033 Commercial Pilot Flight Ii Flight Training, Steelman Library
Avip 3033 Commercial Pilot Flight Ii Flight Training, Steelman Library
Syllabus Repository
No abstract provided.
Avip 4041 Multi-Engine Rating Flight Training, Steelman Library
Avip 4041 Multi-Engine Rating Flight Training, Steelman Library
Syllabus Repository
No abstract provided.