Digital Commons Network^™

Creating A Colab Notebook Based On The Tutorial Of The Simpy Python Library, Mary Deepika Basani

Masters Projects

This project introduces an interactive Google Colab notebook designed to familiarize users with the core functionalities of the SymPy Python library, a powerful tool for symbolic computation. SymPy offers an extensive range of capabilities essential for mathematical modeling, algebraic operations, calculus, and matrix manipulations. The notebook serves as an educational platform, allowing users to experiment with small examples and explore practical applications of symbolic computation in real time. Organized into sections, the notebook focuses on key SymPy features such as simplification, equation solving, differentiation, integration, and matrix operations. Each section includes clear explanations, practical demonstrations, and interactive exercises, helping users …

Re: Comment Letter For Final Bpsou Insufficiently Reclaimed Sites Belle Of Butte (Bres No. 8 & Ur-39) Remedial Action Work Plan (Rawp) Request For Change Ir-2024-Ra-01 (Dated December 3, 2024), Molly Roby

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.

Data Intensive Method For Processing Defect Detection And Mitigation For Composites, Deepak Kumar

Doctoral Dissertations and Master's Theses

Composite manufacturing without processing defects is a crucial step in satisfying the production, performance, and quality requirements of composite materials in various industries. Autoclave processing enables manufacturing of high-quality composite parts with excellent mechanical properties, whereas additive manufacturing (AM) offers adaptability to complex designs and streamlined processes. However, each method presents unique challenges; despite the benefits, autoclave processes can still result in processing defects, and AM is particularly susceptible to processing anomalies owing to the novelty of the process. Ensuring the quality and reliability of composite manufacturing is essential to fully capitalize on the advantages offered by both techniques. Artificial …

Real-Time Feedback-Driven Framework For Automated Cybersickness Mitigation, Md Jahirul Islam

Master's Theses

As technologies are becoming more advanced day by day, the embracement of virtual reality (VR) technology among users is also increasing in daily activities for various purposes, and subsequently, the barrier between the real and virtual world is fading. Despite the versatile uses, cybersickness (CS) is a major problem which is induced among users due to the immersive VR experience. There is a plethora of research findings and methods to measure the users’ CS such as virtual reality sickness questionnaire (VRSQ), simulator sickness questionnaire (SSQ), fast motion scale questionnaire (FMS), and others. Recently, machine learning approaches have also been adopted …

Custom Cathode Optimization For Electropolishing Additively Manufactured 316l Stainless Steel, Kasandra Escarcega Herrera

Mechanical Engineering ETDs

Laser powder bed fusion (LPBF) has become increasingly popular for its ability to rapidly manufacture complex metallic parts. However, the surface properties of as-built LPBF parts may degrade overall performance due to tortuous surface features. Consequently, post-processing like electropolishing (EP) to reduce the surface asperities is often needed for LPBF parts to perform as expected. Utilizing experimental and computational approaches, this project aims to more uniformly EP complex shaped parts made from LPBF 316L. For the experimental approach, parts with a three-dimensional T-shape were printed out of 316L stainless steel and EP using an acidic-based and a polyethylene glycol/NaCl-based electrolyte. …

Ge/Sige Quantum Wells: Material For The Post-Moore Era, Troy Alexander Hutchins-Delgado

Optical Science and Engineering ETDs

This dissertation demonstrates high-quality germanium quantum wells on a 200 mm silicon wafer platform, enabling novel device possibilities. Partnering with a commercial silicon-germanium epitaxy supplier, we obtained shallow, undoped germanium quantum wells with high-crystalline quality, confirmed through x-ray diffraction, secondary ion mass spectroscopy, high-resolution scanning transmission electron microscopy, and energy dispersive x-ray spectroscopy. Hall bar devices fabricated on single quantum wells revealed that surface preparation can tune transport properties while maintaining peak mobilities around 10⁵ cm²V⁻¹s⁻¹. Manganese-germanide spintronic contacts were integrated via solid-state reaction, with contact quality assessed through Schottky diodes, transfer length …

Landslide Mapping, Characterization, And Hazard Assessment With 3d Slope Stability Modeling In White Bluffs, Washington State, Anna Tsitsivas

Dissertations and Theses

Slope failures shape the landscape by moving unstable material downslope and, in doing so, become a great hazard to all those in their path. Understanding the mechanisms that control landslide location, timing, size, type, and runout - and therefore hazards - requires a deep understanding of the local geology, stratigraphy, and groundwater conditions. Along White Bluffs, in south-central Washington, landslides of several failure styles have likely been triggered by an increased water table in recent decades, threatening both farmland behind the bluffs and habitat below. This study focuses on characterizing potential groundwater sources and determining controls on spatial and temporal …

Ire1Α Silences Dsrna To Prevent Taxane-Induced Pyroptosis In Triple-Negative Breast Cancer, Longyong Xu, Fanglue Peng, Qin Luo, Yao Ding, Fei Yuan, Liting Zheng, Wei He, Sophie S Zhang, Xin Fu, Jin Liu, Ayse Sena Mutlu, Shuyue Wang, Ralf Bernd Nehring, Xingyu Li, Qianzi Tang, Catherine Li, Xiangdong Lv, Lacey E Dobrolecki, Weijie Zhang, Dong Han, Na Zhao, Eric Jaehnig, Jingyi Wang, Weiche Wu, Davis A Graham, Yumei Li, Rui Chen, Weiyi Peng, Yiwen Chen, Andre Catic, Zhibin Zhang, Bing Zhang, Anthony M Mustoe, Albert C Koong, George Miles, Michael T Lewis, Meng C Wang, Susan M Rosenberg, Bert W O'Malley, Thomas F Westbrook, Han Xu, Xiang H-F Zhang, C Kent Osborne, Jin Billy Li, Matthew J Ellis, Mothaffar F Rimawi, Jeffrey M Rosen, Xi Chen

Faculty, Staff and Students Publications

Chemotherapy is often combined with immune checkpoint inhibitor (ICI) to enhance immunotherapy responses. Despite the approval of chemo-immunotherapy in multiple human cancers, many immunologically cold tumors remain unresponsive. The mechanisms determining the immunogenicity of chemotherapy are elusive. Here, we identify the ER stress sensor IRE1α as a critical checkpoint that restricts the immunostimulatory effects of taxane-chemotherapy and prevents the innate immune recognition of immunologically cold triple-negative breast cancer (TNBC). IRE1α RNase silences taxane-induced dsRNA through RIDD (Regulated IRE1-Dependent Decay) to prevent NLRP3 inflammasome–dependent pyroptosis. Inhibition of IRE1α in Trp53−/− TNBC allows taxane to induce extensive dsRNAs that are sensed …

The Rise, Fall, And Resurgence Of Phage Therapy For Urinary Tract Infection, Jacob J Zulk, Kathryn A Patras, Anthony W Maresso

Faculty, Staff and Students Publications

In the face of rising antimicrobial resistance, bacteriophage therapy, also known as phage therapy, is seeing a resurgence as a potential treatment for bacterial infections including urinary tract infection (UTI). Primarily caused by uropathogenic Escherichia coli, the 400 million UTI cases annually are major global healthcare burdens and a primary cause of antibiotic prescriptions in the outpatient setting. Phage therapy has several potential advantages over antibiotics including the ability to disrupt bacterial biofilms and synergize with antimicrobial treatments with minimal side effects or impacts on the microbiota. Phage therapy for UTI treatment has shown generally favorable results in recent …

Estimation Of Prevalence Of Autoimmune Diseases In The United States Using Electronic Health Record Data, Aaron H. Abend, Albert M. Lai, Et Al.

2020-Current year OA Pubs

BACKGROUNDPrevious epidemiologic studies of autoimmune diseases in the US have included a limited number of diseases or used metaanalyses that rely on different data collection methods and analyses for each disease.METHODSTo estimate the prevalence of autoimmune diseases in the US, we used electronic health record data from 6 large medical systems in the US. We developed a software program using common methodology to compute the estimated prevalence of autoimmune diseases alone and in aggregate that can be readily used by other investigators to replicate or modify the analysis over time.RESULTSOur findings indicate that over 15 million people, or 4.6% of …

Out-Of-Focus Signal Rejection For In Vivo Po2 Measurements Using Two-Photon Phosphorescence Lifetime Microscopy, Qi Pian, Baoqiang Li, Ikbal Şencan-Eğilmez, Xiaojun Cheng, Jay Dubb, Xinyue Huang, Buyin Fu, Srinivasa Rao Allu, Mohammad Abbas Yaseen, Anna Devor, Sergei A Vinogradov, Sava Sakadžić

2020-Current year OA Pubs

Two-photon phosphorescence lifetime microscopy has been a key tool for studying cerebral oxygenation in mice. However, the accuracy of the partial pressure of oxygen (pO

Characterizing The Risk Of Meteorite Ejecta To Future Lunar Surface Operations, Jacob Yates

Theses and Dissertations

In-situ materials provided adequate shielding against the risk of meteorite ejecta for future lunar surface operations. Both regolith simulant and simulant-epoxy mixtures stopped simulated ejecta projectiles with velocities at or near lunar escape velocity. Those depth penetrations for those two in-situ related materials were shallow inside 3 cm and may prove to be influential in future mission planning of lunar surface operations. The lunar surface poses a potential risk from meteoroid ejecta for future lunar surface operations. The safety ramifications of long-term crewed missions for the Artemis program, NASA’s lunar program, are being investigated or reconsidered from the previous Apollo …

A Conjugate Of An Egfr-Binding Peptide And Doxorubicin Shows Selective Toxicity To Triple-Negative Breast Cancer Cells, Phi-Phung Than, Shih-Jing Yao, Emad Althagafi, Kamaljit Kaur

Pharmacy Faculty Articles and Research

Selective targeting of cancer cells via overexpressed cell-surface receptors is a promising strategy to enhance chemotherapy efficacy and minimize off-target side effects. In this study, we designed peptide 31 (YHWYGYTPERVI) to target the overexpressed epidermal growth factor receptor (EGFR) in triple-negative breast cancer (TNBC) cells. Peptide 31 is internalized by TNBC cells through EGFR-mediated endocytosis and shares sequence and structural similarities with human EGF (hEGF), a natural EGFR ligand. Unlike hEGF, peptide 31 does not induce cell migration in TNBC cells. A novel conjugate of peptide 31 with doxorubicin (Dox) retains selectivity for TNBC cells and exhibits significant toxicity comparable …

Small Molecule With Big Impact: Metarrestin Targets The Perinucleolar Compartment In Cancer Metastasis, Vivek Kashyap, Bhuvnesh Sharma, Divya Pandey, Ajay K. Singh, Godwin Peasah-Darkwah, Bhupesh Singh, Kuldeep K. Roy, Murali Yallapu, Subhash Chauhan

School of Medicine Publications

Metarrestin (ML246) is a first-in-class pyrrole-pyrimidine-derived small molecule that selectively targets the perinucleolar compartment (PNC). PNC is a distinct subnuclear structure predominantly found in solid tumor cells. The occurrence of PNC demonstrates a positive correlation with malignancy, serving as an indicator of tumor aggressiveness, progression, and metastasis. Various promising preclinical results have led to the clinical translation of metarrestin into a first-in-human trial. This review aims to summarize (i) the current understanding of the structure and function of PNC and its role in cancer progression and metastasis, (ii) key findings from studies examining the effect of metarrestin on various cancers …

Exploring The Accuracy Of Interferometric Quantum Measurements Under Conservation Laws, Nicolò Piccione, Maria Maffei, Andrew N. Jordan, Kater W. Murch, Alexia Auffèves

Mathematics, Physics, and Computer Science Faculty Articles and Research

A (target) quantum system is often measured through observations performed on a second (meter) system to which the target is coupled. In the presence of global conservation laws holding on the joint meter-target system, the Wigner-Araki-Yanase theorem and its generalizations predict a lower bound on the measurement’s error (Ozawa’s bound). While practically negligible for macroscopic meters, it becomes relevant for microscopic ones. Here, we propose a simple interferometric setup, arguably within reach of present technology, in which a flying particle (a microscopic quantum meter) is used to measure a qubit by interacting with it in one arm of the interferometer. …

A Ravelin Outwork Uncovered In The Ottoman Fortifications Of The Old City Of ‘Akko, Joppe Gosker

'Atiqot

A small salvage excavation in ‘Akko exposed the remains of a previously unknown ravelin outwork in the counterscarp of the Ottoman-period fortifications—a previously unknown military feature—which cut through earlier Crusader and Hellenistic layers. Ravelins are known components of city fortifications in Europe from the late sixteenth and seventeenth centuries, continuing in use in the nineteenth century. In ‘Akko, it seems that the construction of the ravelin was not completed.

Trebuchets Were Not Siege Guns, So Why Use Them?, Michael S. Fulton

'Atiqot

Counterweight trebuchets were the most powerful ballistic weapons of their day, but their association with later siege guns has led to misunderstandings of their destructive capabilities. This article is an attempt to correct some misguided ideas by providing a short overview of the power and value of mechanical artillery and contextualizing its use in the Levant during the twelfth and thirteenth centuries. After addressing the origin of certain theories that these engines were far more destructive than seems to have been the reality, a brief assessment of their actual power is conducted by looking at the ways sources exaggerate the …

The Old Sword And The Sea: A Medieval European Sword Off The Coast Of Newe-Yam, Joppe Gosker, Jacob Sharvit, Izhak Hershko, Dan Braitman, Yotam Asscher

'Atiqot

This article examines a sword discovered on the seabed near Newe-Yam, providing an analysis of its physical characteristics. The location of the discovery and the submarine iron corrosion processes are described. The sword, covered in a biogenic crust, was studied using non- and minimally invasive techniques, and compared with contemporary swords. A European origin and an approximate date in the twelfth–thirteenth centuries CE are proposed. The study also discusses the role of swords in Medieval European society, their association with authority and chivalry, and the romantic perceptions concerning Crusader swords.

Power And Control In Crusader Acre (‘Akko): The Fortifications Of The Genoese Quarter, Edna J. Stern, Eliezer Stern, Fabrizio Benente

'Atiqot

An impressive fortification system on the northern border of the Genoese Quarter at Crusader-period Acre was discovered, comprising a defensive wall built of bossed ashlars and incorporating arrow slits, a fortified gate leading to the quarter through a vaulted passageway and a projecting tower with two levels of arrow slits. The gate and parts of the passageway were blocked, apparently during the Crusader period, as a consequence of the Saint Sabas War. This war broke out following a dispute between Venice and Genoa over ownership of a monastery located on the border between their quarters, near the port, which was …

Evidence Of The Roman Attack On The Third Wall Of Jerusalem At The End Of The Second Temple Period, Kfir Arbiv

'Atiqot

Remains of a first-century CE wall segment and a tower base uncovered in the Russian Compound, Jerusalem, shed light on the course of the Third Wall in the west of the city and the fierce battle that took place there in the First Jewish Revolt. A concentration of ballista stones and other weapons at the site support the evidence furnished by Josephus in Jewish War, describing the battle at the Third Wall and the siege imposed by Titus on Jerusalem in 70 CE. The archaeological evidence and the historical sources enable a reconstruction of the battle between the Roman army …

Establishing A Secure Sharing Environment Using Partial Cryptographic Keys, Salmaan Rashid

Defensive Publications Series

A system for establishing a secure sharing environment using partial cryptographic keys. The proposed system uses a complete cryptographic key divided into multiple partial keys and provided to two or more participants. The participants attest each TEE of the secure sharing environment desired for use and send, to each TEE, their respective partial key. Each TEE combines the received partial keys to generate the complete cryptographic key. Using the complete cryptographic key, the TEEs can securely communicate and share data with each other.

Volume 41-1 Complete Issue, C. Nicholas Raphael

The Geographical Bulletin

Volume 41-1 Complete Issue

Drinking Water Issues And Management In The Republic Of The Philippines, William James Smith, Jr

The Geographical Bulletin

Major drinking water issues and management schemes in the Republic of the Philippines are examined utilizing a political geographic perspective. By examining these issues and management schemes, administrators in developing countries, such as the Philippines, can provide more effective drinking water management for their citizens. Effective drinking water management is an essential building block in the foundation of sustainable development. This type of socio-political and economic research demonstrates the importance of equity in "safe" drinking water distribution, and the value of watershedbased and integrated natural resource management. The importance of recognizing the provision of safe drinking water as a human …

Interview With Jim Fields, Coo (Pitt Ohio), Elizabeth Gingerich

The Journal of Values-Based Leadership

No abstract provided.

Book Review: Ai [Artificial Intelligence] Fundamentals For Business Leaders, Eya Mahouachi

The Journal of Values-Based Leadership

Artificial Intelligence Fundamentals for Business Leaders: Up to Date with Generative AI (Byte-sized Learning Book 1) is a recent book in a series of four on Artificial Intelligence. It is authored by I. Almeida, the Chief Transformation Officer at Now Next Later AI, an AI advisory, training, and publishing business that supports organizations with their AI strategy, transformation, and governance.

This book is organized around understanding AI, Data and Data Management, Machine Learning, Deep Learning, Model Selection and Evaluation, and Generative AI. The last chapter incorporates an assignment for leaders. This book employs an effective approach to help readers grasp …

How To Create A Mentoring Culture In An Organization, M. S. Rao

The Journal of Values-Based Leadership

The purpose of this paper is to provide basic inputs about the concept of mentoring to the readers. It touches on the role of mentoring in leadership and mentoring that is essential for entrepreneurs. It focuses on the myths and truths in mentoring. It suggests that there is more need to explore deeply about entrepreneurial mentoring. It helps look at the role of leaders in leadership mentoring. It stresses that there should be a blend of both inside and outside mentors to make the mentoring meaningful and fruitful. It may provide further scope for emerging areas in mentoring like lateral …

The Association Of Leadership Styles With Psychosocial Safety Climate: The Case Of Authentic Leadership, Eugene Laloo, Robyn Coman, Natalia K. Hanley

The Journal of Values-Based Leadership

Psychosocial safety climate (PSC) is an organisation-level construct that measures an organisation’s commitment to the prevention of psychological harm in the workplace and has been identified as a lead indicator for psychological hazards. A key factor in PSC is senior leaders’ involvement through the establishment of policies, procedures, and practices for the prevention of psychological harm in the workplace. While leadership has been identified as an antecedent for a favourable PSC, the impact of different leadership styles on PSC has not been extensively studied.

This article reports a multivariate study of five contemporary leadership styles and their impact on PSC. …

The Leadership Identity Presented On Linkedin, Carl L. Tolbert

The Journal of Values-Based Leadership

LinkedIn has evolved in a way similar to other social media platforms but is unique in that it focuses on professional networking and careers. Many professionals seek to showcase their leadership skills and philosophies as part of a publicly showcased online persona. This paper aimed to examine the posts specific to leadership and thematically investigate presentation strategies, motivation, and purposes behind the posts. The paper begins with a historical review from the inception of LinkedIn through pivotal milestones in the history of the company. Key concepts from the literature are then reviewed specific to social media use and motivations behind …

Kitkats And Boiling Kettles: Understanding Reciprocal Relationships In The Workplace, Gavin Mason, Garry Nicholson

The Journal of Values-Based Leadership

Often referred to as a law, principle, norm or rule, reciprocity can be defined as a state or condition of free interchange or mutual responsiveness. This paper considers the importance of reciprocity in organisational settings, whilst identifying three reciprocal exchange behaviours of which leaders should be aware. A Socratic dialogue using the Nelson/Heckmann approach is adopted as a research method, with the primary methodological concern being that of the axiological field of philosophy. Axiology deals with the nature of value and asks what is intrinsically worthwhile. This can lead to multiple questions about what we value in an organisational context. …

Rethinking Leadership Roles In A Future With Dei, Mostafa Sayyadi, Michael J. Provitera

The Journal of Values-Based Leadership

No abstract provided.