Digital Commons Network^™

Pre-Clinical Protective Potentials Of Carica Papaya Constituents In Experimentally Induced Anemia, Hassan Abdulsalam Adewuyi, Adamu Yusuf Kabiru, Hadiza Lami Muhammad, Halimat Yusuf Lukman, Mayowa Solomon Owolabi, Ibrahim Jonathan, Ahmed M El-Gazzar, Mohamed H Mahmoud, Gaber El-Saber Batiha, Bashir Lawal

Faculty, Staff and Students Publications

OBJECTIVE: Anemia is a pathological condition characterized by reduced oxygen bioavailability and/or changes in hematological parameters. This study investigated the anti-anemic activities of

METHOD: Twenty-seven rats were randomized into nine groups of three rats as follows; group 1 was the normal (non-induced) group, 2-9 were anemic rats administered 1 mL distilled water, standard drug (3 mg/kg body weight (bw) ferrous sulphate), 100, 300 and 500 mg/kg bw of crude methanolic extract of CP (CMECP) of the leaf and 100, 300 and 500 mg/kg bw of CMECP of the seed respectively in the first stage of the study. In the second …

Assessing Interatomic Potentials For Molecular Dynamics Simulation Of Soybean Oil Pyrolysis, Tanner Garrett Rust

Graduate Theses/Dissertations

The world today relies on hydrocarbon combustion for many reasons, including its high energy density that provides ease of transportation. However, hydrocarbons sourced from fossil fuels are not expected to last forever. Biodiesel, a renewable alternative, has many attractive benefits but comes with other downsides. Biodiesel can gel in cold environments and may leave residue in an engine. Pyrolysis of biodiesel has shown promise in addressing these common detriments. Inducing pyrolysis on biodiesel feedstock (commonly soybean oil in the USA) would be an attractive option presuming it continues to produce fossil fuel analogs similar to biodiesel pyrolysis. Herein, Langevin molecular …

Quantum Dots' Toxicity: A Multi-Level Investigation On The Impact Of Quantum Dots On The Actin Cytoskeleton, Nhi Le

Graduate Theses/Dissertations

Quantum dots (QDs) are fluorescence nanomaterials with unique optical and physical properties. As such, they are highly sought after for their potential use in several biomedical and industrial applications. Despite their vast potential, recent studies have suggested that quantum dots are toxic to cells. Yet, the mechanism of quantum dots’ toxicity remains unclear. As such, my thesis aims to comprehensively examine the mechanism of quantum dots’ toxicity, emphasizing how quantum dots disrupt the actin cytoskeleton. In this study, I used RNA sequencing and mass spectrometry to investigate the influence of CdSe/ZnS QDs on the transcriptomic proteomic level of Saccharomyces cerevisiae …

Brighter Days, Erich J. Eastman

Graduate Theses/Dissertations

Brighter Days is a musical composition for choir, solo voice, and guitar, depicting the stages of an emotional journey through five separate movements. Each movement represents a different set of feelings, exploring themes of frustration, perseverance, hope, elation, and other sentiments. The movements are interconnected, employing key relationships and cross-references throughout the work. Musical styles vary, and genres are blended to create tonal landscapes that are both unique and accessible. Brighter Days is an expressive new work about finding light in darkness and coming to terms with oneself.

Quantum Dot Effect On Endocytic Pathways And Eisosome Organization, Onyinye Dorathy Okafor

Graduate Theses/Dissertations

Despite the promising applications of Quantum Dots (QDs) in the biomedical field, the long-lasting effects of QDs on the cell remain poorly understood. To comprehend the mechanisms underlying the toxic effects of QDs in yeast, I characterized defects associated with receptor-mediated endocytosis (RME) as well as on pinocytosis using Saccharomyces cerevisiae as a model in the presence of CdSe/ZnS QDs. My findings revealed that QDs led to an inefficient RME at the early, intermediate, and late stage of endocytic patch maturation at the endocytic site, with the prolonged lifespan of GFP-fused yeast fimbrin (Sac6-GFP), a late marker of endocytosis. The …

Perfectly Disconnected: Examining The Role Of Neuroticism In The Perfectionism Social Disconnection Model, Brooklynn Madison Cook

Graduate Theses/Dissertations

Numerous studies have examined the effects of various personality traits on social functioning. Perfectionism is a multidimensional personality trait that has been related to lower social connection and perceived social support. The Perfectionism Social Disconnection Model (PSDM) suggests that perfectionism traits lead to interpersonal disconnection as those with perfectionism are inclined to intensely fear rejection due to the innate need to be accepted by others. Conflictingly, this leads to a distant presentation in social relationships, impeding interpersonal connection. While researchers have employed several variables to further examine the interpersonal nature of perfectionism, neuroticism has yet to be considered in the …

Word Reimagined: Analyzing Fanfiction's Transformative Force And Relationship With The Young Adult Literary Landscape, Megan Louise Reaves

Graduate Theses/Dissertations

In exploring the reciprocal relationship between fanfiction and Young Adult (YA) literature, this thesis investigates how these two forms of storytelling, influenced by authors such as Marissa Meyer and Rainbow Rowell, have profoundly impacted the literary landscape. Marissa Meyer's The Lunar Chronicles series and Rainbow Rowell's novels Fangirl and Carry On serve as prime examples of this dynamic interaction. Drawing from the rich traditions of oral storytelling and folklore, fanfiction and YA literature have undergone significant development and popularity, particularly in the twenty-first century, thanks to technological advancements and the rise of online communities. This thesis contends that despite their …

Experience Of Parents Attending A Perinatal Lullaby Program, Emily J. Skeers

Graduate Theses/Dissertations

Previous research performed with mother–infant dyads has demonstrated that infant–directed singing may make significant contributions to mother–infant attachment, may reduce infant stress, reduce maternal stress, assist mothers and babies with emotional regulation, improve mother–infant interactions, prevent colic, and improve infant sleep. Despite these benefit potentials, parents of today are much less likely to sing to their infants than parents of previous generations. Attendance of postnatal lullaby education programs has been associated with increased maternal singing at home and confidence in their parenting role. Perinatal lullaby programs are not represented in the literature. This qualitative study explored the lived experiences of …

Sharing Is Caring: The Effect Of Interpersonal Interdependence, Shame Proneness, And Empathy On One's Physiological Response When Witnessing And Experiencing Shame, Lauren Michelle Smith

Graduate Theses/Dissertations

This study identifies the impact of interpersonal interdependence on one’s physiological response when one witnesses shame and examines the predictive qualities of shame-proneness and empathy on these differences. It is predicted that interpersonal interdependence, shame proneness, and empathy will affect the physiological response. A One-way Repeated Measures ANOVA, single linear regression, and multiple linear regression were used to assess differences. The findings showed that participants experienced significantly higher levels of physiological arousal when experiencing shame personally compared to witnessing it in others (stranger and loved one). It was also found that shame-proneness has a negative relationship with physiological arousal when …

Geology Of The Bishop 7.5-Minute Quadrangle And Geophysical Modeling To Constrain Syndepositional Deformation Of The Black Warrior Foreland Basin, Joseph Edward Lane

Graduate Theses/Dissertations

The Black Warrior basin is a foreland basin formed by the Ouachita–Appalachian orogeny during the late Paleozoic Era. Mississippian strata record the transition from the carbonate platform within the Tuscumbia Limestone to the clastic-rich units within the overlying Pride Mountain Formation and Hartselle Sandstone. The western and southern-most fringes of the Black Warrior basin are covered by thin, post orogenic Cretaceous sediments of the East Gulf Coastal Plain. Geological mapping of the Bishop 7.5-Minute quadrangle revealed subtle deformation in Mississippian strata in the form of gentle folds (

Cold Hardiness In Vitis Interspecific Hybrid 'Chambourcin'-Based Population, Tabinda Shahid

Graduate Theses/Dissertations

The susceptibility of grapevines to low-temperature injury presents a significant challenge, particularly in the United States. Traditional European grape cultivar, Vitis vinifera ‘Cabernet sauvignon’, faces bud damage at temperatures below freezing. On the other hand, Vitis interspecific hybrid ‘Chambourcin’, exhibits greater tolerance to sub-zero temperatures. The objective of this research was to conduct Differential Thermal Analysis (DTA) on 273 F₁ hybrid genotypes generated from a cross of ‘Chambourcin’ × ‘Cabernet Sauvignon’ to quantify bud cold hardiness by identifying the freezing exothermic reactions. Low temperature exotherm (LTE) profiles, over two dormant seasons (December to February 2022-2024), revealed 15 interspecific hybrid …

Transforming The Culture Of Care, Implementation Of Developmentally Supportive Care In The Neonatal Intensive Care Unit, Taylor Ann Jones

Graduate Theses/Dissertations

The current study examines the implementation of the evidence-based practices of the neonatal integrative developmental care model in the neonatal intensive care unit and how these practices are implemented in reference to initiation method and frequency. In recent years, research examining the effectiveness of individualized, developmentally supportive care to infants in the NICU has demonstrated a variety of positive effects. Although great strides have been made in efforts to provide developmentally supportive care, wide variability and inconsistency remain in the quantity and quality of experience for infants and families in the NICU. Even though a hospital may incorporate developmentally supportive …

The Kinetic Modulation Of Α - Synuclein Fibrillation And Toxicity By 4-Phenylbutyric Acid, Kristos Awuah Baffour

Graduate Theses/Dissertations

ABSTRACT

The Protein misfolding and aggregation of alpha-synuclein (α-syn) into neurotoxic amyloids underlies the pathogenesis of neurodegenerative diseases such as Parkinson's disease (PD). 4-Phenylbutyrate (PBA), an FDA drug approved for treating urea cycle disorders, has garnered significant attention as a potential chemical chaperone for targeting alpha-synuclein (α-syn) aggregation. Using in vitro assays, we demonstrated that PBA treatment alters the pattern of α-syn aggregation, as evidenced by reduced formation of oligomeric species and its increased susceptibility to proteolytic cleavage under the influence of PBA. Proteinase K assay, surface plasmon resonance, and Nile red studies indicate that PBA interacts with the extensive …

Body. Freedom. Choice: Creating Artwork In Post-Roe America, Erin Sedra

Graduate Theses/Dissertations

I knew from a young age that I never wanted children. Whenever I expressed my disinterest in motherhood, I was often met with bewilderment, disapproval, and hostility. The church I was raised in taught me that my value and worth as a woman directly correlated with the power of my birthing hips. This fundamentalist upbringing has significantly shaped my relationship with my femininity, my body, and my artwork. When I feel powerless, turning to my art gives me a sense of control and self-expression. This body of work began as a reaction to the overturning of Roe v. Wade and …

Context Detection With Word Embedding And Emotionally Relevant Keyword Search For Smart Home Environment, Brent Anderson

Graduate Theses/Dissertations

Voice-enabled virtual assistants have gained widespread popularity and are increasingly common in smart homes. To enhance customization and personalization in user experiences with these assistants, implementing a context detection feature is beneficial. This feature enables the virtual assistant to gather more information from the audio data of short voice conversations with users, helping it maintain awareness of the conversation and respond more aptly. In this thesis, I propose a novel context detection approach for virtual assistants in smart homes, named WERKS, which leverages user emotions. WERKS stands for word embedding with emotionally relevant keyword search. The WERKS approach incorporates emotion …

Exploring Band Students' Motivations Regarding Instrument Selection, Aaron S. Morley

Graduate Theses/Dissertations

When choosing a beginning band instrument, students are faced with a choice that may be influenced by a variety of factors. These factors also interest band directors, who want students to choose an instrument that will be a good fit for their strengths while also being engaging to them. To assist directors in guiding students through instrument selection it is helpful to know what factors could influence students when they are choosing an instrument. To identify the factors that students report as impactful, beginning band students in five northwest Missouri school districts were surveyed about the influence of selected factors. …

Recollection, Shelby Ann Theis-Lukenbill

Graduate Theses/Dissertations

My work is inspired by life's transient nature and objects' enduring capacity to house memories. The delicate sculptures I create combine second-hand objects with paper to capture the essence of moments and possessions that define personal histories. The objects I use represent more than their form or chemistry; they are imbued with fragments of history and memory that I am driven to preserve. In this work, the sentimental nature and purpose of my belongings hold an equal or greater value than the physical nature and purpose of those belongings. I illuminate an object’s sentimentality by combining its form with painted …

Mining Contamination Of Legacy Deposits On Floodplains Along Turkey Creek, Western Border Of The Ozark Highlands, Hannah Riley Eades

Graduate Theses/Dissertations

Historical mining activities in the Tri State mining district in Southwest Missouri from 1850 to 1950 resulted in widespread metal contamination of stream sediments. Beginning in the 1840s, land disturbances associated with Euro-American settlement and agricultural expansion increased runoff and soil erosion rates resulting in the deposition of contaminated alluvium or legacy sediment on floodplains. This study assesses zinc (Zn) and lead (Pb) contaminated legacy deposits in cut-bank exposures along floodplains in Turkey Creek Watershed (119 km²) which drained mining areas in Missouri. Ore production histories were used date metal contamination profiles and calculate floodplain deposition rates in legacy deposits. …

Origin Of Carbonate Mud Mounds In Southwestern Missouri, Jared Mcavoy

Graduate Theses/Dissertations

Small carbonate mud mounds are found in Lower Mississippian strata of southwestern Missouri. These compare favorably with larger mounds, known as Waulsortian mounds, located in the Meuse River valley of southern Belgium. The origin of Waulsortian and similar mounds is unknown, but they commonly are interpreted as accumulations of mud, where the presence of biological organisms responsible for supposed bio-construction remains uncertain. Alternative hypotheses are that these may have been non-cohesive slump or cohesive slide masses. Multiple techniques, including δ13C and δ18O isotopic analyses and unmanned aerial vehicle photography, were used to determine the most feasible working hypothesis. Determining the …

Empowered Womanhood In Rokeya Sakhawat Hossain’S “Sultana’S Dream” And Greta Gerwig’S Barbie: Keys To The Ideal World, Tasnuva Tabassum

Graduate Theses/Dissertations

Rokeya Sakhawat Hossain’s “Sultana’s Dream” (1905) and Greta Gerwig’s Barbie (2023) present feminist utopias separated by more than a century. Despite the temporal gap, both works introduce worlds where traditional gender roles are reversed. This thesis explores Hossain’s and Gerwig’s suggestions to create ideal worlds through empowerment of women. Considering evolution of feminist utopian thought from the beginning of the twentieth century to the beginning of the twenty-first, and the differences in feminisms from East to West, this thesis analyzes the narrative structures, thematic elements, and cultural contexts of these works. Despite differences, both authors seek not just female but …

Enhancing Workplace Climate And Learning Outcomes In Aba Services: Prosocial Approaches And Peak Instruction With Autistic Learners, Stephanie Vickroy

Graduate Theses/Dissertations

The practice of Applied Behavior Analysis (ABA) heavily relies on the relationship between high quality client services and the direct care staff who implement these services. This thesis combines two manuscripts which discuss the field of behavior analysis in terms of clinical approaches. The first chapter evaluated intervention outcomes of 55 autistic learners undergoing language and cognitive training guided by PEAK (Promoting Emergence of Advanced Knowledge System; Dixon, 2014) within ABA services. Pre-post analyses of performance on the PCA revealed significant increases in PCA scores following 6-months of intervention and consistent gains in scores occurred across all four …

Gastrointestinal Parasite Prevalence Of Missouri Dogs Against Various Risk Factors, Mattie Cobban

Graduate Theses/Dissertations

Gastrointestinal parasites infect various mammalian species, including dogs, causing symptoms like diarrhea, lethargy, anemia, and possible death. Some gastrointestinal parasites possess zoonotic potential posing risk to dog owners, shelter workers, trainers, veterinary staff, groomers, and the public since dogs have access to public areas such as parks and stores. This study aims to understand the prevalence of gastrointestinal parasites of dogs in southwest Missouri under different environmental conditions. Fecal samples were collected from the Polk County Humane Society, local dog trials, and dog owners. The Mini-FLOTAC fecal flotation method was employed to quantify the type and number of parasite ova …

Evaluating The Normative Development And Efficacy Of The Life Functional Module, Kaitlyn A. Hui

Graduate Theses/Dissertations

The Life Functional Module (Dixon, 2020) is an all-encompassing assessment and curriculum designed to promote learner’s independence and well-being by teaching daily living, social, leisure, and other functional or meaningful skills. There is a wide variety of curricula that is currently used in applied-behavior analysis services and programming, including the Essentials for Living, Assessment of Functional Living Skills (AFLS), and the Verbal Behavior Milestones Assessment and Placement Program (VB-MAPP). However, there is a lack of research in empirical evidence in regards to the efficacy of these curricula (Ackley et. al, 2019; Padilla et. al, 2023). The first manuscript of this …

Assessing The Effects Of Experimentally Contrived Negative Emotional Contexts On Affect, Willingness, And Impulsivity, Amanda Nicole Middleton

Graduate Theses/Dissertations

Emotions are a naturally occurring and unavoidable part of life. To investigate the role that negative emotional experiencing plays in transfer of stimulus function, relational behavior, and intervention effectiveness, this thesis combines and explores the implications of two manuscripts that examine the effects of negative emotional contexts. Specifically, the first chapter presents research demonstrating the ability of operant schedules of reinforcement and respondent relational training to result in acquired affective and willingness stimulus functions. A between groups design demonstrated that when paired with a frustration-inducing task, negatively valenced functions can be established for arbitrary stimuli, and when observational pairing was …

Evaluating The Maintenance Of Verbal Relational Operants Following Peak Programming, Jenna Huskey

Graduate Theses/Dissertations

The Promoting the Emergence of Advanced Knowledge (PEAK) Relational Training System is an assessment and curriculum tool developed for basic and advanced language skills using behavior analytic approaches (Dixon, 2016). Maintenance describes the retention of performance following the progression of time. In the present study, the purpose was to determine if maintenance was achieved on previously mastered PEAK programs, both in terms of the content and the verbal relational operant (i.e., generalization to new, untrained content). De-identified data were analyzed for five autistic learners (six to fourteen years old) receiving ABA services at a Midwestern clinic. Programs were selected from …

Evaluating The Interdependency Of The Peak Comprehensive Assessment As It Relates To Performance Estimation And Curricular Programming For Autistic Learners, Julia A. Busam

Graduate Theses/Dissertations

Assessments are widely used by behavior analysts throughout the field of Applied Behavior Analysis when determining curriculum and intervention for individuals with autism spectrum disorder (ASD). This thesis combines and discusses two collaborative manuscripts that revolve around the subject of one commonly used ABA assessment and curriculum. The PEAK Relational Training System (PEAK, Dixon 2014-2016) provides a wide-ranging assessment and training program that incorporates Skinnerian verbal operant learning and derived relational responding expressed in contemporary Relational Frame Theories (Hayes et al., 2001). The PEAK Comprehensive Assessment (PEAK-CA; Dixon, 2018) was developed to standardize and streamline assessments from all four PEAK …

Co-Evolving Multi-Agent Transfer Reinforcement Learning Via Scenario Independent Representation, Ayesha Siddiqua

Graduate Theses/Dissertations

Multi-Agent Reinforcement Learning (MARL) addresses complex tasks involving cooperation and competition among agents, training them to develop optimal policies for collective goals. However, facilitating simultaneous learning for multiple agents is challenging because the complexity increases rapidly with the number of agents. Current methods encompass a variety of centralized, decentralized, semi-centralized, and hybrid approaches to balance the trade-offs between computational efficiency, scalability, and coordination in MARL. In this study, I employed a centralized training with semi-centralized execution (CTSCE) framework, utilize both local observations from agents and abstracted global observations to effectively train agents in cooperative environments. Additionally, earning complex, domain-specific tasks …

Million-Year Melt-Presence In Mogollon-Datil Volcanic Field Rhyolites: Constraining The Histories Of The Bursum Caldera Resurgent Domes, Ethan Wagner

Graduate Theses/Dissertations

The Mogollon-Datil volcanic field which is located in southwestern New Mexico, is the result of punctuated volcanism and the transition between arc and rift magmatism. The resurgent domes within the 28 Ma Bursum caldera records the transition from rhyolitic to basaltic andesite volcanism that occurred between 27-26 Ma. Using a combination of new zircon U-Pb ages using chemical abrasion isotope dilution thermal ionization mass spectrometry (CA-ID-TIMS) with zircon U-Pb geochronology and trace element contents by laser ablation inductively coupled plasma mass spectrometry (LA-ICPMS) and whole rock and mineral trace element contents and isotope geochemistry this study investigates the temporal and …

The Influence Of Relational Frames On Climate Purchasing And Policy, Lauren Rose Hutchison

Graduate Theses/Dissertations

Evaluative conditioning refers to the effect that occurs when two stimuli are paired together, resulting in a change in the evaluation or function of one of the stimuli. Evaluative conditioning has been researched in various fields of study, such as advertisement and public administration, but synthetization efforts of these results with a relational frame theory approach, and vice versa, have been limited. This thesis used de-identified data from prior approved research to integrate and discusses two manuscripts that provide a relational frame theory perspective to evaluative conditioning effects. Study 1 extends a previous experiment by Matthews et al. (2022) through …

Disturbance-Prone Ozark Streams: Interactions Between Plants And The Stream Environment, Alexis Renea Reifsteck

Graduate Theses/Dissertations

Ozark streams are extremely diverse ecosystems, despite frequent flood disturbance. Plant communities are frequently altered by bed-moving floods but are extremely resilient. We know that land-use, sediments, and nutrients can impact plant communities, but more can be divulged about how plants alter communities and how environmental variables influence plant community composition in disturbance-prone Ozark streams. To address this, I examined two key aspects of Ozark stream ecosystems: the role of American Water Willow, Justicia americana, in structuring aquatic habitats and the factors influencing gravel bar plant community composition. In the first chapter, I investigated how J. americana, a …