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Review Of "The Spanish Blue Division On The Eastern Front, 1941-1945: War, Occupation, Memory" By Xosé M. Núnez Seixas, Ben H. Shepherd

Canadian Military History

Review of The Spanish Blue Division on the Eastern Front, 1941-1945: War, Occupation, Memory by Xosé M. Núnez Seixas

Review Of "Combat Stress In Pre-Modern Europe" Edited By Owen Rees, Kathryn Hurlock And Jason Crowley, Matthew Barrett

Canadian Military History

Review of Combat Stress in Pre-modern Europe edited by Owen Rees, Kathryn Hurlock and Jason Crowley

Demographic Characteristics, Perinatal Smoking Patterns, And Risk For Neonatal Health Complications Among Pregnant Smokers In The United States Who Begin Using Electronic Cigarettes During Pregnancy: A Descriptive Study Using Population-Based Surveillance Data., Hui Nian, Rachel Odland, Samantha Mindlin, Lin Ammar, Hilary Tindle, Angela M Miller, Kelli K Ryckman, Ethan Xie, Tina V Hartert, Brittney M Snyder, Steven M Brunwasser, Pingsheng Wu

Rowan-Virtua School of Osteopathic Medicine Departmental Research

INTRODUCTION: Health agencies have called for research evaluating e-cigarette (EC) use in supporting prenatal smoking cessation. This study aimed to describe (1) the characteristics of smokers who begin using electronic cigarettes (ECs) during pregnancy, (2) how frequently smokers reduce or eliminate pre- and post-natal combustible cigarette (CC) use, and (3) the risk for neonatal health complications among smokers who initiate ECs during pregnancy.

AIMS AND METHODS: Pregnant women using CCs exclusively during prepregnancy, who participated in a U.S. surveillance study, were classified by their reported late-pregnancy smoking behavior as CC-exclusive users, EC initiators, or quitters. EC initiators were further subclassified …

Fall Ensembles (October 22, 25, 2024), Lindenwood University

Student Music Performance Programs

Event program for Fall Ensembles (October 22, 25, 2024), Lindenwood University.

San Diego Collaboration For Conservation: Sustaining The Region's Legacy Of Biodiversity Conservation, Tessa Tinkler, Darbi Berry, A-Bel Gong, Bryan Cardenas, Daniela Olguin, Connelly Meschen, Eo Hanabusa

Environment

We are living through significant environmental, social, political, and economic challenges. These challenges have strained our communities and humanbuilt systems, as well as our interconnected habitats, wildlife, and natural systems. Lack of adequate infrastructure to withstand natural disasters and climate change, as well as historical and presentday inequities in resources across neighborhoods, are examples of the multifaceted and interconnected threats contributing to the accelerated loss of our rich biodiversity. This natural abundance is integral to our region’s health, history, and continued prosperity.

Umn Morris Students Lead Campus Tree Survey Project, Communications And Marketing

Campus News Archive

No abstract provided.

Modeling Suitable Habitats Of Stingless Bee Klanceng (Tetragonula Laeviceps) In Merbabu Mountain Areas Related To Elevation, Temperature, And Humidity Variables, Cornelius Devito Atmaja, Sukirno Sukirno, Hari Purwanto, Andriwibowo Andriwibowo, Hanindyo Adi Prabowo

Jurnal Penelitian Kehutanan Wallacea

Klanceng is one of the stingless bee species in Indonesia with the scientific name Tetragonula laeviceps. This bee species has sustainable economic values since it has a role as a pollinator. This species is also common in mountainous areas, including Merbabu Mountain, Central Java. Despite this bee being very common, information about potential distributions of this bee is very limited, and this information is needed for its management. This study aimed to model the potential habitat for T. laeviceps using species distribution modeling (SDM) with elevation, temperature, and humidity as predictors. The model was built based on the T. …

Factors Behind Cessation Of Illegal Logging By Local Communities For Valuable Timber-Producing Endemic Species, Hopea Celebica, Putu Oka Ngakan, Nasri Nasri, Putu Supadma Putra, Fardi Ali Syahdar, Arif Koesharyadi

Jurnal Penelitian Kehutanan Wallacea

Hopea celebica is a species of Dipterocarpaceae that produces strong and durable wood. This species is endemic to Sulawesi Island, where its spread is restricted to specific habitat types in the southern part of the island. The high quality of the wood has exposed this species to high levels of illegal logging and is endangered. However, in the last two decades, the threat of logging to this tree species has ceased to occur. Through field surveys and interviewing of respondents in 6 small FGDs, this study aims to determine the factors behind the cessation of illegal logging activities. We found …

Ethnoecology: The Community Adaptation Patterns Of Forest Management In Grobogan Central Java, Noor Fatmawati, Sanusi

Jurnal Penelitian Kehutanan Wallacea

The aims of this research are to describe community adaptation patterns and determine community perceptions regarding forest environmental management. This qualitative research was studied using an ethnoecological approach with the research focus being the people of the Perhutani area of ​​Grobogan Regency. This research carried out the data collection through interviews, observation and documentation, with the main informant being Pesanggem as a forest land manager. This research produced the first findings in the form of community adaptation patterns in managing the environment covering three aspects, namely ecological adaptation, economic adaptation and social adaptation in the Pesanggem community in Gedangan Village, …

Differential Hepatic Expression Of Mirna In Response To Aflatoxin B1 Challenge In Domestic And Wild Turkeys, Kade Jorud, Kristelle M. Mendoza, Thomas Kono, Roger A. Coulombe, Kent M. Reed

Animal, Dairy, and Veterinary Science Faculty Publications

Aflatoxin B1 (AFB₁) is a major foodborne mycotoxin that poses a significant economic risk to poultry due to a greater degree of susceptibility compared to other agricultural species. Domesticated turkeys (Meleagris gallopavo) are especially sensitive to AFB₁; however, wild turkeys (M. g. silvestris) are more resistant. A lack of functional isoforms of hepatic glutathione S-transferases (GSTs), an enzyme that plays a role in the detoxification of aflatoxin, is suspected as the reason for the increased sensitivity. Previous studies comparing the gene expression of domesticated and wild turkeys exposed to AFB₁ identified …

Experimental Characterization, Computational Investigation, And Structure-Property–Activity Relationship Studies Of Nickel Ferrite Nanostructures, Ali Ben Ahmed

Polytechnic Journal

Intending to predict the multifunctionality of Nickel ferrite in several technological and medical fields, we have prepared nickel ferrite nanostructure by coprecipitation method. X-ray Diffraction (XRD) is used to determine the crystalline structure and phase composition of materials by analyzing the pattern of X-rays scattered by the atoms within the material. Fourier Transform Infrared Spectroscopy (FTIR) provides information about a material's chemical bonds and functional groups by analyzing how it absorbs infrared light at various wavelengths. Scanning Electron Microscopy (SEM) offers high-resolution images of the material's surface morphology and texture by scanning it with a focused beam of electrons. Transmission …

Election Law And Democratic Theory, James A. Gardner

Contributions to Books

Election law is the body of law by which a society implements its commitment to democracy. Any meaningful evaluation of the suitability or effectiveness of a society’s election law therefore requires some inquiry into the nature of the society’s democratic commitments—the theory or conception of democracy to which it subscribes. Virtually all such theories are rooted in philosophical liberalism but nevertheless come in many varieties. Reconstructing a society’s democratic commitments can be complicated by its failure to articulate or even to reflect upon them. In the United States, that difficulty is compounded by a long history of evolution in American …

Machine Learning Strategies For Enhancing Reconstruction And Classification In Diffuse Optical Tomography And Photoacoustic Tomography For Ovarian And Breast Cancer, Yun Zou

McKelvey School of Engineering Graduate Student Theses & Dissertations

This dissertation investigates the application of advanced deep learning techniques to enhance biomedical imaging technologies, specifically focusing on Diffuse Optical Tomography (DOT) and Photoacoustic Tomography (PAT) for the diagnosis and treatment of ovarian and breast cancers. By integrating convolutional neural networks (CNNs) and other machine learning architectures, the research addresses critical challenges in image reconstruction, 3D rendering, and classification tasks within medical imaging domains. For DOT, a novel machine learning model with physical constraints (ML-PC) was developed, significantly improving the quality and accuracy of image reconstructions from diffuse optical signals. This model effectively managed the inherently noisy and indirect measurements …

Minutes, Curriculum Committee Meeting, Tuesday, October 22, 2024, Curriculum Committee

Curriculum Committee Minutes

No abstract provided.

Preparation And Efficacy Evaluation Of Chicken Egg Yolk Sourced Igy Against The Venoms Of Cobra, Krait, Russell’S Viper, And Saw-Scaled Viper, Gayathri G

Theses and Dissertations

Envenomation resulting from snakebites is widely recognized as an alarming health risk in tropical and sub-tropical areas. The big four snakes including Naja naja, Bungarus caeruleus, Daboia russelli, Echis carinatus are responsible for most of the envenomation in India. The current therapy for snake envenomation is immunoglobulins, produced from serum or plasma of horses or sheep. To overcome the drawbacks of current antivenom, chicken egg yolk (IgY) antibodies have recently emerged as one of the most promising research avenues.

In this study, the efficacy of chicken egg yolk sourced antisnake venom (ASV) IgY against the big four venoms was evaluated …

Native Mass Spectrometry Of Membrane Protein-Lipid Interactions In Different Detergent Environments, Smriti Kumar, Lauren Stover, Lie Wang, Hanieh Bahramimoghaddam, Ming Zhou, David H Russell, Arthur Laganowsky

Faculty, Staff and Students Publications

Native mass spectrometry (MS) reveals the role of specific lipids in modulating membrane protein structure and function. Membrane proteins solubilized in detergents are often introduced into the mass spectrometer. However, detergents commonly used for structural studies, such as dodecylmaltoside, tend to generate highly charged ions, leading to protein unfolding, thereby diminishing their utility in characterizing protein–lipid interactions. Thus, there is a critical need to develop approaches to investigate protein–lipid interactions in different detergents. Here, we demonstrate how charge-reducing molecules, such as spermine and trimethylamine-N-oxide, enable the opportunity to characterize lipid binding to the bacterial water channel (AqpZ) and …

Cortical Acetylcholine Dynamics Are Predicted By Cholinergic Axon Activity And Behavior State, Erin Neyhart, Na Zhou, Brandon R Munn, Robert G Law, Cameron Smith, Zakir H Mridha, Francisco A Blanco, Guochuan Li, Yulong Li, Ming Hu, Matthew J Mcginley, James M Shine, Jacob Reimer

Faculty, Staff and Students Publications

Acetylcholine (ACh) is thought to play a role in driving the rapid, spontaneous brain-state transitions that occur during wakefulness; however, the spatiotemporal properties of cortical ACh activity during these state changes are still unclear. We perform simultaneous imaging of GRAB-ACh sensors, GCaMP-expressing basal forebrain axons, and behavior to address this question. We observed a high correlation between axon and GRAB-ACh activity around periods of locomotion and pupil dilation. GRAB-ACh fluorescence could be accurately predicted from axonal activity alone, and local ACh activity decreased at farther distances from an axon. Deconvolution of GRAB-ACh traces allowed us to account for sensor kinetics …

Gene Therapy For Fat-1 Prevents Obesity-Induced Metabolic Dysfunction, Cellular Senescence, And Osteoarthritis, Ruhang Tang, Natalia S Harasymowicz, Chia-Lung Wu, Yun-Rak Choi, Kristin Lenz, Sara J Oswald, Farshid Guilak

2020-Current year OA Pubs

Obesity is one of the primary risk factors for osteoarthritis (OA), acting through cross talk among altered biomechanics, metabolism, adipokines, and dietary free fatty acid (FA) composition. Obesity and aging have been linked to cellular senescence in various tissues, resulting in increased local and systemic inflammation and immune dysfunction. We hypothesized that obesity and joint injury lead to cellular senescence that is typically associated with increased OA severity or with aging and that the ratio of omega-6 (ω-6) to omega-3 (ω-3) FAs regulates these pathologic effects. Mice were placed on an ω-6-rich high-fat diet or a lean control diet and …

Identification Of The N-Terminal Residues Responsible For The Differential Microdomain Localization Of Cyp1a1 And Cyp1a2, Robert M. Fuchs, James R. Reed, J. Patrick Connick, Markéta Paloncýová, Martin Šrejber, Petra Čechová, Michal Otyepka, Marilyn K. Eyer, Wayne L. Backes

School of Graduate Studies Faculty Publications

The endoplasmic reticulum is organized into ordered regions enriched in cholesterol and sphingomyelin, and disordered microdomains characterized by more fluidity. Rabbit CYP1A1 and CYP1A2 localize into disordered and ordered microdomains, respectively. Previously, a CYP1A2 chimera containing the first 109 amino acids of CYP1A1 showed altered microdomain localization. The goal of this study was to identify specific residues responsible for CYP1A microdomain localization. Thus, CYP1A2 chimeras containing substitutions from homologous regions of CYP1A1 were expressed in HEK 293T/17 cells, and the localization was examined after solubilization with Brij 98. A CYP1A2 mutant with the three amino acids from CYP1A1 (VAG) at …

Choral Ensembles Fall Concert (October 22, 2024), Lindenwood University

Student Music Performance Programs

Choral Ensembles Fall Concert (October 22, 2024), Lindenwood University

Mental Illness Amongst Incarcerated Individuals And Its Effect On Gaining Employment, Tionna S. Miller

Theses and Dissertations

More than half the correctional population has a mental health disorder (NIH, 2022). Having a mental health disorder can severely interfere in one’s transition back into the community, specifically surrounding their access to employment. This dissertation analyzes the extent to which the mental health of previously incarcerated individuals affects their employment upon release. Results from this study concluded that having a mental health diagnosis did interfere with previously incarcerated individuals’ access to employment, especially if those individuals were black. This dissertation concludes with a discussion of the findings, limitations, contributions, as well as implications for practitioners, policy makers and researchers.

Early Use Of Long-Acting Injectable Antipsychotics In Bipolar Disorder Type I: An Expert Consensus, Martha Sajatovic

Faculty Scholarship

Introduction: Long-acting injectable antipsychotics (LAIs) are not routinely offered to patients living with bipolar disorder type I (BP-I), despite widespread evidence that supports their benefits over oral antipsychotics, particularly in early disease. Methods: A round-table meeting of psychiatrists convened to discuss barriers and opportunities and provide consensus recommendations around the early use of LAIs for BP-I. Results: LAIs are rarely prescribed to treat BP-I unless a patient has severe symptoms, sub-optimal adherence to oral antipsychotics, or has experienced multiple relapses. Beyond country-specific accessibility issues (e.g., healthcare infrastructure and availability/approval status), primary barriers to the effective use of LAIs were identified …

Effects Of Spontaneous Curvature On Interfacial Adsorption And Collapse Of Phospholipid Monolayers, Bret A. Brandner, Shankar B. Rananavare, Stephen B. Hall

Chemistry Faculty Publications and Presentations

To function effectively, pulmonary surfactant must adsorb rapidly to the alveolar air/water interface but avoid collapse from the surface when compressed to high interfacial densities. Prior studies show that phospholipids in the cylindrical monolayers of the inverse hexagonal (HII) phase adsorb quickly. The monolayers have negative curvature, defined by the concave shape of the hydrophilic face. Formation of the HII structures, however, involves significant disruption of chain-packing. Samples with significant spontaneous curvature, formed in the absence of applied force, may nonetheless have lamellar structures that optimize chain-packing. The experiments here tested whether planar lamellar bilayers formed by phospholipids with negative …

Unmasking Neuroendocrine Prostate Cancer With A Machine Learning-Driven Seven-Gene Stemness Signature That Predicts Progression, Agustina Sabater, Pablo Sanchis, Rocio Seniuk, Gaston Pascual, Nicolas Anselmino, Daniel F Alonso, Federico Cayol, Elba Vazquez, Marcelo Marti, Javier Cotignola, Ayelen Toro, Estefania Labanca, Juan Bizzotto, Geraldine Gueron

Faculty, Staff and Student Publications

Prostate cancer (PCa) poses a significant global health challenge, particularly due to its progression into aggressive forms like neuroendocrine prostate cancer (NEPC). This study developed and validated a stemness-associated gene signature using advanced machine learning techniques, including Random Forest and Lasso regression, applied to large-scale transcriptomic datasets. The resulting seven-gene signature (KMT5C, DPP4, TYMS, CDC25B, IRF5, MEN1, and DNMT3B) was validated across independent cohorts and patient-derived xenograft (PDX) models. This signature demonstrated strong prognostic value for progression-free, disease-free, relapse-free, metastasis-free, and overall survival. Importantly, the signature not only identified specific NEPC subtypes, …

Impact Of Pik3ca Gain And Pten Loss On Mantle Cell Lymphoma Biology And Sensitivity To Targeted Therapies, Nardjas Bettazova, Jana Senavova, Kristyna Kupcova, Dana Sovilj, Anezka Rajmonova, Ladislav Andera, Karla Svobodova, Adela Berkova, Zuzana Zemanova, Lenka Daumova, Vaclav Herman, Alexandra Dolníkova, R Eric Davis, Marek Trneny, Pavel Klener, Ondrej Havranek

Faculty, Staff and Student Publications

Besides many other mutations in known cancer driver genes, mantle cell lymphoma (MCL) is characterized by recurrent genetic alterations of important regulators of the phosphoinositol-3-kinase (PI3K) cascade including PIK3CA gains and PTEN losses. To evaluate the biological and functional consequences of these aberrations in MCL, we have introduced transgenic expression of PIK3CA (PIK3CA UP) and performed knockout/knockdown of PTEN gene (PTEN KO/KD) in 5 MCL cell lines. The modified cell lines were tested for associated phenotypes including dependence on upstream B-cell receptor (BCR) signaling (by an additional BCR knockout). PIK3CA overexpression decreased the dependence of the tested MCL on prosurvival …

Machine Learning Strategies For Enhancing Reconstruction And Classification In Diffuse Optical Tomography And Photoacoustic Tomography For Ovarian And Breast Cancer, Yun Zou

McKelvey School of Engineering Graduate Student Theses & Dissertations

This dissertation investigates the application of advanced deep learning techniques to enhance biomedical imaging technologies, specifically focusing on Diffuse Optical Tomography (DOT) and Photoacoustic Tomography (PAT) for the diagnosis and treatment of ovarian and breast cancers. By integrating convolutional neural networks (CNNs) and other machine learning architectures, the research addresses critical challenges in image reconstruction, 3D rendering, and classification tasks within medical imaging domains. For DOT, a novel machine learning model with physical constraints (ML-PC) was developed, significantly improving the quality and accuracy of image reconstructions from diffuse optical signals. This model effectively managed the inherently noisy and indirect measurements …

Voicing Experiences Of Family Members Providing Care To Loved Ones With A Pituitary Condition, Carly Ellicott, Alyson Norman, Sue Jackson

School of Psychology

Introduction: This paper draws upon lived experiences of family members caring for a relative with a pituitary condition. The rationale for the study stems from the crucial role provided by informal, unpaid carers. Yet in the specific domain of pituitary care, they remain overlooked within empirical research. Therefore, the current study aimed to understand 1) the experiences of family members whose loved ones have a pituitary condition and 2) the information and support needs of family members. Materials and methods: Adopting a qualitative participatory approach, the study involved six family members, each of whom provided care for a loved one …

The Phylogenetically Isolated South African Endemic Diving Beetle Caperhantus Cicurius (Fabricius, 1787): Redescription And Range Extensions (Coleoptera, Dytiscidae, Colymbetinae), David T Bilton, C.R. Turner, M.C. Mlambo

More Faculty of Science and Engineering Research

New distribution records and a redescription are presented for Caperhantus cicurius (Fabricius, 1787), a diving beetle endemic to the Cape region of South Africa, which is only distantly related to other Afrotropical dytiscids. We show that the species is much more widely distributed than previously recognized and present details of occupied habitats for the first time. Caperhantus cicurius occurs throughout the winter rainfall zone in South Africa, from Namaqualand to the Eastern Cape Province, particularly in temporary waters in the Fynbos and Succulent Karoo biomes.

Self-Monitoring With Coping Skills And Lifestyle Education For Hypertension Control In Primary Care, Sonal J. Patil, Eno Obong Udoh

Faculty Scholarship

Self-monitoring with support, lifestyle modifications, and emotion management improves blood pressure (BP). Patients with hypertension need continual support to modify behaviors, but time pressures limit lifestyle education in primary care settings. Using mixed methods, we aimed to study the feasibility and acceptability of an innovative 6-week program that combined self-monitoring with coping skills and lifestyle education for patients with uncontrolled hypertension. Patients with uncontrolled hypertension interested in lifestyle modifications before intensifying medications were enrolled from primary care clinics. Patients self-monitored emotions, behaviors, and BPs and received education from medical providers and mind-body therapists through shared medical appointments (SMAs) with an …

Sars-Cov-2 Anti-N Antibodies Among Healthcare Personnel Without Previous Known Covid-19, Sajal Tiwary, Caroline A O'Neil, Kate Peacock, Candice Cass, Mostafa Amor, Meghan A Wallace, David Mcdonald, Olivia Arter, Kelly Alvarado, Lucy Vogt, Henry Stewart, Daniel Park, Victoria J Fraser, Carey-Ann D Burnham, Christopher W Farnsworth, Jennie H Kwon

2020-Current year OA Pubs

OBJECTIVE: To measure SARS-CoV-2 anti-nucleocapsid (anti-N) antibody seropositivity among healthcare personnel (HCP) without a history of COVID-19 and to identify HCP characteristics associated with seropositivity.

DESIGN: Prospective cohort study from September 22, 2020, to March 3, 2022.

SETTING: A tertiary care academic medical center.

PARTICIPANTS: 727 HCP without prior positive SARS-CoV-2 PCR testing were enrolled; 559 HCP successfully completed follow-up.

METHODS: At enrollment and follow-up 1-6 months later, HCP underwent SARS-CoV-2 anti-N testing and were surveyed on demographics, employment information, vaccination status, and COVID-19 symptoms and exposures.

RESULTS: Of 727 HCP enrolled, 27 (3.7%) had a positive SARS-CoV-2 anti-N test …