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Observing And Estimating Soil Freeze Thaw Processes: From Remote Sensing To Land Surface Modeling, Mahsa Moradikhaneghahi

Doctoral Dissertations

Freezing conditions affect more than half of the exposed land in the Northern Hemisphere in cold seasons, where transitions between frozen and thawed states impact surface and subsurface water and energy budget. Recognized as an Essential Climate Variable (ECV), accurate, reliable and efficient estimates of soil freeze/thaw (FT) processes with a moderate spatiotemporal resolution are needed to fully resolve highly-dynamic processes taking place at the land-atmosphere interface. Active microwave remote sensing and land surface modeling are promising tools for advancing the monitoring of FT as an ECV. My dissertation addresses key scientific gaps in estimating soil FT conditions using active …

Natural Laboratories Of The Deep Sea: Linking Community Composition And Environmental Variables On Low-Temperature Venting Outcrops Of Ridge Flank Hydrothermal Systems To Explore Potential Impacts Of Climate Change, Inform Habitat Suitability Models, And To Understand The Impacts Of High Bathymetric Resolution On Seafloor Characterization, Anne Marie Hartwell

Doctoral Dissertations

The deep sea covers over two-thirds of the globe and represents 95% of the ocean. Most life on Earth is suspected to live on or near the seabed. Yet, these ecosystems are the least known on Earth and are important to explore as they are home to a diverse array of species that are currently under threat because of multiple anthropogenic pressures, including warming oceans. Exploration of these systems is critical to further the understanding of species interactions, biodiversity and their overall relationship to environmental and terrain variables. Many of these variables are used in species distribution models and technological …

Rational Design Of Polymers For Specific Interactions With Liquid And Solid-State Water, Nick Mitchell

Doctoral Dissertations

Many plants and animals that live in arctic regions possess biological cryoprotecting agents (CPAs) known as antifreeze proteins (AFPs) which protect them against cryoinjury in their native subfreezing environment. AFPs and their synthetic biomimetics have received increasing attention as potential candidates for various industrial and bio-medical applications. Despite the interest in developing synthetic, macromolecular CPAs; a full understanding of the antifreeze process induced by these remains elusive. To explore this, we have synthesized a series of water- soluble polyol-based polymers with systematic variation of their chain architectures.While AFPs are well-known for their ice nucleation and recrystallization inhibition activity along with …

Connecting Conservation: Modeling And Socializing Climate Connectivity For Land Conservation, Melissa M. Clark

Doctoral Dissertations

As the climate changes, species must either adapt, relocate, or face extinction. This pressing reality underscores the importance of promoting climate connectivity, which ensures that habitats and landscapes remain interconnected, allowing species to move and adapt as climate conditions shift. Given the challenges posed by ongoing climate change, it is crucial that land conservation decisions incorporate climate connectivity. Conservation goals should be informed by the latest connectivity models and be practical for implementation by on-the-ground practitioners. This dissertation aims to bridge the gap between these two critical needs, which are not always well-integrated in conservation work. Modeling connectivity in a …

Senior Mental Health Clinicians’ Understanding Of Their Self-Efficacy While Providing Services At Community-Based Agencies, Rukiya Symister

Walden Dissertations and Doctoral Studies

Many mental health clinicians strive to provide their clients with rehabilitative and psychotherapy services resulting in a client gaining stable income and housing. However, the role of a senior mental health clinician (SMHC) is not without its challenges of trying to balance their well-being while dealing with increased coworker turnover, demanding caseloads, and limited access to community resources to provide clients with getting their lives back on track, thereby impacting clinicians’ understanding of their self-efficacy. Much of the research on self-efficacy has focused on mental health clients, mental health graduate students, and mental health trainees, often leaving out the lived …

Enhancing 21 U.S.C. §§ 355, 356, And 360 To Encompass Artificial Intelligence-Based Drug Design And Manufacturing Methods, Aj Tsang

Michigan Technology Law Review

Despite newfound attention to how artificial intelligence (AI) may accelerate pharmaceutical development, federal regulators may find that current statutes are ambiguous or silent about their applicability to AI-based drug design and manufacturing methods. This poses a serious problem in the era of Loper Bright and the Major Questions Doctrine. As federal agencies struggle to adjust to courts’ growing demand for Congress to craft clear, explicit, and express delegations of authority, this note develops a statutory framework in which the Food and Drug Administration (FDA) would have more flexibility to regulate the use of AI in advanced drug manufacturing. Guided by …

Molecular And Cellular Programs Underlying The Development Of Bovine Pre-Implantation Embryos, Zongliang Jiang

Faculty Publications

Early embryonic mortality is a major cause of infertility in cattle, yet the underlying molecular causes remain a mystery. Over the past half century, assisted reproductive technologies such as in vitro fertilisation and somatic cell nuclear transfer have been used to improve cattle reproductive efficiency; however, reduced embryo developmental potential is seen compared to their in vivo counterparts. Recent years have seen exciting progress across bovine embryo research, including genomic profiling of embryogenesis, new methods for improving embryo competence, and experimenting on building bovine embryos from stem cell cultures. These advances are beginning to define bovine embryo molecular and cellular …

Variant Of The Lactase Lct Gene Explains Association Between Milk Intake And Incident Type 2 Diabetes, Kai Luo, Guo Chong Chen, Yanbo Zhang, Jee Young Moon, Jiaqian Xing, Brandilyn A. Peters, Mykhaylo Usyk, Zheng Wang, Gang Hu, Jun Li, Elizabeth Selvin, Casey M. Rebholz, Tao Wang, Carmen R. Isasi, Bing Yu, Rob Knight, Eric Boerwinkle, Robert D. Burk, Robert C. Kaplan, Qibin Qi

Population and Public Health Science Faculty Publications

Cow’s milk is frequently included in the human diet, but the relationship between milk intake and type 2 diabetes (T2D) remains controversial. Here, using data from the Hispanic Community Health Study/Study of Latinos, we show that in both sexes, higher milk intake is associated with lower risk of T2D in lactase non-persistent (LNP) individuals (determined by a variant of the lactase LCT gene, single nucleotide polymorphism rs4988235) but not in lactase persistent individuals. We validate this finding in the UK Biobank. Further analyses reveal that among LNP individuals, higher milk intake is associated with alterations in gut microbiota (for example, …

An Examination Of Homo Naledi Early Juveniles Recovered From The Rising Star Cave System, South Africa, Juliet K. Brophy, Debra R. Bolter, Marina Elliott, John Hawks, Lee R. Berger

Faculty Publications

Background: Six Homo naledi early juveniles were recovered from U.W. 101 (Dinaledi Chamber), U.W. 102 (Lesedi Chamber), and U.W. 110 in the Rising Star cave system. Aim: This paper develops the information for the H. naledi early juvenile life stage, as defined by a combination of deciduous and permanent dentition, and the eruption of the first permanent molar. Subjects and methods: The growing number of young individuals recovered from the Rising Star cave system allows us to gain a better understanding of their variation, or lack thereof, and provides a basis to estimate broad ranges for age at death of …

Flooded Mangrove Landscapes Hide Ancient Maya Coastal Sites In Belize, Heather I. Mckillop

Faculty Publications

Evidence of ancient Maya exploitation of salt, other marine resources, settlement, and sea trade is hidden in flooded mangrove landscapes on the cays, mainland, and in shallow offshore locations on the south coast of Belize. This article includes a discussion of the coastal economy from the Middle Preclassic through the Postclassic periods (600 B.C.–A.D. 1500). Data from sites discovered and excavated since 1982 in the coastal area of the Port Honduras and Paynes Creek National Park support a model of coastal reliance on marine resources and tree crops. The need for a regular supply of coastal salt to inland cities …

Formulation Design And Development For Extended-Release Drug Delivery System, Sheng Feng

Electronic Theses and Dissertations

The drug delivery system enables the release of the active pharmaceutical ingredient to achieve a desired therapeutic response. Conventional, non-controlled drug delivery systems are unable to deliver the drug at a sustained rate which leads to poor bioavailability, fluctuations in plasma drug concentration, and potential side effects. The extended drug delivery system enables drug delivery at a sustained or predetermined rate to achieve maximum efficacy and safety. Different routes of drug administration, along with various extended-release dosage forms have been extensively developed such as oral delivery, parenteral delivery, transdermal delivery, ocular delivery, and tumor delivery among others. This dissertation developed …

Efficient Design Of Neural Network Hardware Accelerator For Enhanced Performance In Deep Learning Systems, Tamador Nadem Mohaidat

Electronic Theses and Dissertations

Artificial intelligence (AI) hardware accelerator is an emerging research for several applications and domains. The hardware accelerator aims to provide high computational speed while retaining low cost and high learning performance. The main challenge is to design complex machine learning models on hardware with high performance. In this thesis, the aim is to develop the hardware implementation of perceptron within a neural network. Innovative hardware-based approaches are explored to optimize perceptron networks, enhancing accuracy, reliability, and fault tolerance while minimizing resource requirements and power consumption.

A thorough investigation into machine learning accelerators and associated challenges was initially conducted. The hardware …

Heterologous Expression, Isolation, And Metabolomic Profiling Of Myxobacteria To Explore Their Potential In Natural Product Biosynthesis, Nawal Mohamed Hamed Elsayed Shehata

Electronic Theses and Dissertations

Myxobacteria are distinguished by their ability to produce a spectrum of natural products,positioning them as an active resource for therapeutic discovery. These products include metabolites with significant antibacterial, antifungal, cytotoxic, antiviral, and immunosuppressive properties. Current synthetic biology tools for the exploration of myxobacteria are not as advanced as those for the well-studied Streptomyces. This thesis presents an evolution of synthetic biology techniques specifically designed for the exploitation of myxobacteria in the realm of natural product discovery. Chapter One investigates the potential of myxobacteria to act as heterologous hosts due to their large genomes and their capacity for diverse biosynthetic processes. …

An Argument Against Positivist Separability, Nichalus Zoltan Vali

Electronic Theses and Dissertations

One of the most influential views associated with legal positivism is that of the separability thesis. Primarily associated with H.L.A Hart, this thesis is widely understood to be the view that there is no necessary connection between law and morality. However, John Gardner takes this to be a naïve interpretation of separability that fails to adequately characterize legal positivism and which Hart himself did not endorse. Instead, Hart and other legal positivists were committed to the view that whether a norm is legally valid depends on its sources (i.e., social facts such as official engagement with the norm) and not …

Iuphar-Review: The Integration Of Classic Psychedelics Into Current Substance Use Disorder Treatment Models, David Yaden, Andrea Berghella, Peter Hendricks, Mary Yaden, Michael Levine, Julia Rohde, Sandeep Nayak, Matthew Johnson, Albert Garcia-Romeu

SKMC Student Presentations and Publications

Substance use disorders (SUDs) have an enormous impact on public health. With classic psychedelic-assisted therapies showing initial promise in treating multiple SUDs, it is possible that these treatments will become legally available options for patients with SUDs in the future. This article highlights how classic psychedelic-assisted therapies might be integrated into current clinical practice. We first describe contemporary evidence-based treatments for SUDs and highlight how classic psychedelic-assisted therapies might fit within each treatment. We suggest that classic psychedelic-assisted therapies can be integrated into most mainstream evidence-based SUD treatments that are currently used in clinical settings, indicating broad compatibility of classic …

Effect Of Fluid Elasticity On The Emergence Of Oscillations In An Active Elastic Filament, Kathryn G. Link, Robert D. Guy, Becca Thomases, Paulo E. Arratia

Mathematics Sciences: Faculty Publications

Many microorganisms propel themselves through complex media by deforming their flagella. The beat is thought to emerge from interactions between forces of the surrounding fluid, the passive elastic response from deformations of the flagellum and active forces from internal molecular motors. The beat varies in response to changes in the fluid rheology, including elasticity, but there are limited data on how systematic changes in elasticity alter the beat. This work analyses a related problem with fixed-strength driving force: the emergence of beating of an elastic planar filament driven by a follower force at the tip of a viscoelastic fluid. This …

Atomistic Simulation Of Pfas And Graphene: Interactions For Water Applications, Bashar Moufeed Awawdeh

Electronic Theses and Dissertations

The contamination of drinking water by per- and polyfluorinated alkyl substances (PFAS) is a global issue. PFAS have been widely utilized in a variety of applications, including water and stain-resistant coatings, fire suppression foams, cosmetics, paints, and adhesives. They have been detected in soils and rivers globally due to their widespread use and resistance to degradation. The strong C–F bonds of PFAS make them exceedingly stable and hard to remove. In order to remediate PFAS contamination in the environment, it is essential to develop selective adsorbent materials that can effectively capture a wide range of PFAS structures. On April 10, …

Cationic Charge-Shifting Polymers As Improved Vectors For Nucleic Acid Delivery, Alexander Fortenberry

Electronic Theses and Dissertations

This work investigates the development and application of charge-shifting polycations for gene delivery, focusing on their synthesis, characterization, and applications for in vitro mRNA delivery. Utilizing poly(2-vinyl-4,4-dimethylazlactone) (PVDMA), this study explores modifications with various reactive handles, such as alcohol, thiol, and amine groups, to create cationic amide-, ester-, and thioester-functionalized polycations. These modifications aim to exploit the charge-shifting capabilities of the polycations to form stable polyplexes with nucleic acids, promoting the efficient intracellular release of the genetic cargo.Initial studies first examine the charge-shifting properties of PVDMA-based polycations under different pH and temperature conditions. This work highlights the potential of these …

Ecological And Evolutionary Ramifications Of Host-Parasite Interaction In Aquatic And Model Ecosystems, Akacia Halliday-Isaac

Electronic Theses and Dissertations

Host-parasite interactions are ubiquitous and have negative risks and consequences on individual, population, and evolutionary scales. These risks and consequences include altered population densities, changes in interspecies interactions, and rapid changes in host phenotypes. In this thesis, I seek to understand the ecological and evolutionary ramifications of host-parasite interactions within ecosystems. To do this, I investigated the presence and environmental correlates of potential host-parasite interactions in a freshwater ecosystem and used a model ecosystem to explore how past host-parasite coevolution affects community assembly dynamics and future adaptation in the presence of new stressors. To examine the presence of potentially parasitic …

Acoustic Localization In Reverberant Environment, Xing Yang

Electronic Theses and Dissertations

The main goal of this dissertation is to develop algorithms to accurately locate and detect underwater oil leakages through sounds emitted by oil-induced bubbles recorded by passive hydrophones. These algorithms aim to create an early warning system to prevent or identify catastrophic oil spills from pipelines, wellheads, and seafloor seepage.

Effects Of Off-Season Fall-Winter Farm Field Flooding On Nitrogen Gas Production, Andrew Rosson

Electronic Theses and Dissertations

Increased nitrogen (N) fertilizer use and cultivation of N-fixing crops have dramatically increased agricultural N inputs to the global N cycle. Excess N on agricultural lands is highly susceptible to loss through runoff or atmospheric emissions, potentially as a greenhouse gas (GHG). Nitrous oxide (N2O), a GHG with a warming potential ~300 times that of carbon dioxide (CO2), primarily enters the atmosphere through denitrification, which converts bioavailable nitrate (NO3-) to inert nitrogen gas (N2), with N2O as an intermediate. Wetlands are crucial for de-nitrification and N regulation due to their wet, anoxic soils, but have declined worldwide, including substantial losses …

Edtech For Learning Outcomes And Impact: A Comprehensive Approach, Priyanka Sharma

Student learning processes

A precise estimation of learners' abilities is the first and foremost step in personalized learning including EdTech solutions. Predictive analytic techniques such as Item Response Theory (IRT), Bayesian Knowledge Tracing (BKT), and Performance Factor Analysis (PFA) are established practices to achieve this purpose. However, the complexity, cost, and time involved in calibration, and the challenges in online implementation, have led to the adoption of simpler alternatives such as Elo, machine learning, and artificial intelligence. Nevertheless, the estimation of abilities is just one facet of personalized learning, and designing effective personalized learning experiences is equally essential to guide learners through their …

Ic 008 Guide To University Of Texas Medical School Records, 1969-2006, University Of Texas Medical School At Houston

Institutional Finding Aids

University of Texas Medical School records primarily consists of newsletters like Scoop, IATRO year books, annual reports, directories for consultation referrals, and other types of ephemera. The collection roughly dates from 1979 to 2011. See more at IC 008.

Braving The Elements: Loss Of Metals From Mardi Gras Beads Due To Handling And Weathering, Thomas O. Carmichael, Ruth H. Carmichael

Gulf and Caribbean Research

The largest Mardi Gras celebrations in the U.S. are found along the Gulf of Mexico coast. With increasing awareness of and concern for environmental and human health risks due to pollution from Mardi Gras celebrations, there is a need for studies to quantify potential harms. We conducted a 2—part study to determine whether use—related handling and weathering of common Mardi Gras beaded necklaces results in loss of potentially harmful metals to the environment at levels of ecological or human health concern. Our data indicate that weathering and use—related handling can cause metals to be shed from the metallic coating of …

Michael Anthony Poirrier, Hyun Jung Cho, Patrick D. Biber, Martin T. O'Connell, Carol D. Franz

Gulf and Caribbean Research

No abstract provided.

Recruitment Of Juvenile Snapper (Lutjanidae) In The Middle Florida Keys: Temporal Trends And Fine-Scale Habitat Associations, Jack C. Olson, Ariel Tobin, Mareike D. Duffing Romero, Alejandro Acosta

Gulf and Caribbean Research

Juvenile recruitment is a major factor in the establishment and maintenance of local population structures of coral reef fishes. An understanding of the factors that affect juvenile recruitment and survival help explain spatial and temporal patterns in adult abundance, especially of commercially and recreationally fished species. Here, we examined the distribution and juvenile recruitment of 5 snapper species: Mutton Snapper (Lutjanus analis), Lane Snapper (L. synagris), Schoolmaster (L. apodus), Gray Snapper (L. griseus), and Yellowtail Snapper (Ocyurus chrysurus) collected in 1,314 seine samples conducted between 2007 and 2019 in the …

Applying The Disaster Risk Assessment Framework To Sargassum Inundation In Barbados, A. Karima Degia, Micaela Small, Hazel A. Oxenford

Gulf and Caribbean Research

Episodic influxes of pelagic Sargassum into the Caribbean result in inundation of coastlines with significant negative impacts to the environment, society, and economy. The spatial complexities of this issue demand a strategy that combines spatial planning with an analytical framework that can systematically unpack the underlying factors to inform effective management. We test the application of the United Nations Disaster Risk Reduction (UNDRR) conceptual framework for disaster risk assessment to Sargassum inundation, with a focus on the hazard and exposure components of risk, using Barbados, a Caribbean Small Island Developing State (SIDS), as a case study. We first consider in …

An Aggregation Of The Pandalid Shrimp, Heterocarpus Ensifer, On Deep Reef Habitats Of The West Florida Slope, Eastern Gulf Of Mexico, Steve W. Ross

Gulf and Caribbean Research

Heterocarpus ensifer A. Milne—Edwards (1881) (Crustacea: Pandalidae), armed nylon shrimp, is widely distributed in the western and eastern North Atlantic Ocean. In the western Atlantic this shrimp occurs from off North Carolina to Brazil and in the Gulf of Mexico (GOM), western Bahamas, and Caribbean Sea at depths of 170—885 m. Despite its widespread occurrence, ecology or biology information for this species are sparse, and in situ observations of abundance, behavior and habitat preferences are particularly lacking. During extensive submersible and ROV observations on and near deep—reefs in the north—central and eastern GOM, a remarkably large aggregation of H. ensifer …

“To Try The Difference”: Encountering A Different Self In Henry Neville’S Isle Of Pines, Andrew Fleck

Literatures and Cultural Studies Faculty Publications

It is critical that the imagined space of Henry Neville’s Restoration-era novella, The Isle of Pines, is an island, a space cut off from the mainland where history and culture can unfold in different ways. The island, encountered unintentionally by “civilized” Europeans during a Dutch trading voyage across the Indian Ocean, has a previously unknown population. Rather than a new, long-established nation of islanders, however, the population are the descendants of five castaways from an English shipwreck. Viewed through the lens of the unfamiliar, these islanders adhere to tropes associated with discovery narratives; simultaneously, the islanders carry with them …

Geophysical Survey And Archaeological Investigations At The Jeremiah Lee Mansion And Brick Kitchen, 2022 Marblehead, Massachusetts, Christa M. Beranek, John M. Steinberg, Carolyn Mikowski

Andrew Fiske Memorial Center for Archaeological Research Publications

In spring and summer of 2022, students and staff from the Fiske Center for Archaeological Research at UMass Boston completed a geophysical survey and test excavations at the Jeremiah Lee property at 157 and 161 Washington Street in Marblehead, Massachusetts. These were the first known archaeological investigations of the property. Work in 2022 focused on the area between the house and the Brick Kitchen and the eastern part of the yard behind the house. The Lee property, now owned by the Marblehead Museum, is a large, complex urban lot. Our work in 2022 showed that the archaeological preservation of deposits …