The Effects Of Early Exposure To Prescription/Illicit Drugs And Drug Metabolites On Larval Zebrafish Behavioral And Motor Function Development, Jacob Thomas, Dena Weinberger, Bikram Subedi, Brandon Capps

Murray State Theses and Dissertations

THE EFFECTS OF EARLY EXPOSURE TO PRESCRIPTION/ILLICIT DRUGS AND DRUG METABOLITES ON LARVAL ZEBRAFISH BEHAVIORAL AND MOTOR FUNCTION DEVELOPMENT

A Thesis Presented to the Faculty of the Department of Biology

Murray State University

Murray, Kentucky

In Partial Fulfillment of the Requirements for the Degree of Masters In Science

By Jacob Thomas, B.S., Murray State University

December 2024

Acknowledgements

Brandon Capps, who pretty much did a whole third of the legwork on this project and saved me lots of headaches;

Chandler Maddox, one of the University of Kentucky’s finest undergrads who came in from the top rope with a folding chair …

"I Failed My Brother": How Online Radicalization Affects The Family Unit, Serenity Dawn Kollasch

Honors Program Theses

No abstract provided.

Wrongful Convictions, Wrongful Prosecutions And Wrongful Detentions In India, Kent Roach

National Law School of India Review

The first part of this article examines wrongful convictions in India. In part because of the absence of a jury, appellate courts, including the apex court, are more willing to evaluate whether the evidence for a conviction is sufficient than appellate courts in other common law systems. From 2016 to 2022, the High Courts and the Supreme Court have acquitted over two hundred accused in death penalty cases alone. The willingness of appellate courts to acquit is a strength of the Indian system that should be maintained. At the same time, remedied wrongful convictions in India likely represent only the …

Variation-Aware Non-Linear Mapping For Honey-Memristor Based Neuromorphic System, Harshvardhan Uppaluru, Md Mehedi Hasan Tanim, Md Omar Faruque, Mohammed Rafeeq Khan, Zoe Templin, Feng Zhao, Jinhui Wang

Electrical and Computer Engineering Faculty Research & Creative Works

Natural organic memristors are promising synapse candidates for neuromorphic systems due to their significant benefits, such as environmental sustainability, low production and disposal cost, non-volatile storage capability, and bio/CMOS-compatibility. In this paper, experimental evaluations of a neuromorphic system based on honey-memristors are reported. First, honey-memristors are manufactured and tested based on our in-house technology, and then the non-linear characteristics inherent to honey-memristors, which causes inaccurate weight updates and reduces the inference accuracy, are explored. A non-linear mapping (NMP) method is applied to mitigate the effects of non-linearity in honey-memristor, under different scenarios including multiple cycle-to-cycle variations and Analog-to-Digital Converter (ADC) …

Molecular Imaging Nanoprobes And Their Applications In Atherosclerosis Diagnosis, Huari Kou, Hu Yang

Chemical and Biochemical Engineering Faculty Research & Creative Works

Molecular imaging has undergone significant development in recent years for its excellent ability to image and quantify biologic processes at cellular and molecular levels. Its application is of significance in cardiovascular diseases, particularly in diagnosing them at early stages. Atherosclerosis is a complex, chronic, and progressive disease that can lead to serious consequences such as heart strokes or infarctions. Attempts have been made to detect atherosclerosis with molecular imaging modalities. Not only do imaging modalities develop rapidly, but research of relevant nanomaterials as imaging probes has also been increasingly studied in recent years. This review focuses on the latest developments …

Pharmacology Of Boldine: Summary Of The Field And Update On Recent Advances, Juan C. Sáez, Justin C. Burrell, Catherine M. Cahill, D. Kacy Cullen, Lakshmi A. Devi, Ryan J. Gilbert, Zachary A. Graham, Vadim J. Gurvich, Leif A. Havton, Ravi Iyengar, Rajesh Khanna, Edmund F. Palermo, Mustafa Siddiq, Carlos A. Toro, Walter Vasquez, Wei Zhao, Christopher P. Cardozo

Chemical and Biochemical Engineering Faculty Research & Creative Works

Over the past decade, boldine, a naturally occurring alkaloid found in several plant species including the Chilean Boldo tree, has garnered attention for its efficacy in rodent models of human disease. Some of the properties that have been attributed to boldine include antioxidant activities, neuroprotective and analgesic actions, hepatoprotective effects, anti-inflammatory actions, cardioprotective effects and anticancer potential. Compelling data now indicates that boldine blocks connexin (Cx) hemichannels (HCs) and that many if not all of its effects in rodent models of injury and disease are due to CxHC blockade. Here we provide an overview of boldine's pharmacological properties, including its …

Boosting The Microbial Electrosynthesis Of Formate By Shewanella Oneidensis Mr-1 With An Ionic Liquid Cosolvent, Ashwini Dantanarayana, Wassim El Housseini, Kevin Beaver, Monica Brachi, Timothy P. Mcfadden, Shelley D. Minteer

Chemistry Faculty Research & Creative Works

Microbial electrosynthesis (MES) is a rapidly growing technology at the forefront of sustainable chemistry, leveraging the ability of microorganisms to catalyze electrochemical reactions to synthesize valuable compounds from renewable energy sources. The reduction of CO₂ is a major target application for MES, but research in this area has been stifled, especially with the use of direct electron transfer (DET)-based microbial systems. The major fundamental hurdle that needs to be overcome is the low efficiency of CO₂ reduction largely attributed to minimal microbial access to CO₂ owing to its low solubility in the electrolyte. With their tunable physical …

Emergency Surgery: A Plea For Student Debt Relief, Stephen Urciolo

Transactions: The Tennessee Journal of Business Law

No abstract provided.

Gender In The Making Of The Constitution: Proposals For A Feminist Inquiry Into Indian Constitutional History, Achyut Chetan

National Law School Journal

A feminist inquiry into the framing of the Indian Constitution must retrieve and see the interventions of the women members of the Constituent Assembly for what they historically represent, namely, a feminist authorial voice that was developed over a period of time by the pre-Independence women’s movement in India. For a proper understanding of this voice, we must understand the gendered character of the Constituent Assembly, its architecture, its procedures, the dynamics of the gendered relations among its members, and above all, the performative aspects of the debates. This inquiry must also investigate the language employed by the members and …

Ghost-Hunting In Al And The Law, Meghan J. Ryan

Faculty Journal Articles and Book Chapters

Generative AI is booming. This technology offers amazing opportunities for growth in various business sectors and creates the opportunity for swift progress on medical innovations, climate change, world hunger, and innumerable other areas. AI also poses a number of challenges, though, such as replacing human workers and exacerbating pernicious biases. Another major concern about generative AI is singularity-the idea that this technology could surpass human intelligence and subjugate us or render us extinct. Although some commentators discount this possibility, the fact that AI experts such as Geoffrey Hinton, Sam Altman, and Elon Musk share the singularity concern should at least …

Bulletin Ninth District Ny March 2024

Bulletin of the Ninth District Dental Association

The Bulletin of the Ninth District Dental Association is published four times annually in the months of March, May, September and November. It is distributed to all Association members from the counties of Dutchess, Orange, Putnam, Rockland and Westchester in the state of New York.

The Bulletin keeps our members up-to-date on NDDA activities as well as on a variety of topics important to the profession.

Bulletin Ninth District Ny November 2024

Bulletin of the Ninth District Dental Association

The Bulletin of the Ninth District Dental Association is published four times annually in the months of March, May, September and November. It is distributed to all Association members from the counties of Dutchess, Orange, Putnam, Rockland and Westchester in the state of New York.

The Bulletin keeps our members up-to-date on NDDA activities as well as on a variety of topics important to the profession.

4. Robotic Babies - Data, Didactics And Ethics In Social Work, Mads Lund Andersen, Vivi Friis Søgaard, Karin Christiansen, Heike Felzmann, Almundena Navas, Miriam Abietar

Irish Journal of Applied Social Studies

No abstract provided.

3.Ethical Complexities Within The Appearance And Usage Of Social Robots: A Scoping Review, Mads Lund Anderson, Heike Felzmann

Irish Journal of Applied Social Studies

No abstract provided.

Reaching A 'Breaking Point' - Women’S Experiences Of Caring In Ireland During Covid-19, Cliona Loughnane, Mary Hayes

Irish Journal of Applied Social Studies

The inequitable division of care between women and men has been central to the perpetuation of gender inequalities in Ireland and internationally. COVID-19 brought new visibility to the caring needs of society and underlined the need for personal and political structures and supports which account for care. During Ireland’s first lockdown, many women were caring for their families and homes, working in paid employment, providing home-schooling and supporting loved ones outside the home. In May 2020, the Women’s Experiences of Caring during COVID-19 online survey sought to capture the experiences of women providing informal, unpaid care during the pandemic. 85% …

Exploring What Is Old And What Is New About Trauma-Informed Care: Implications For Child Welfare Practice., Maria Lotty

Irish Journal of Applied Social Studies

Trauma-informed care is becoming increasing part of discourse in child welfare practice. This paper explores the current debates and offers some critical reflections relevant for trauma-informed care implementation in child welfare practice. Firstly, the paper discusses the lack of conceptual clarity of a shared understanding for both trauma and trauma-informed care posing challenges for implementation and assessing evidence. Then, it explores the proposed paradigm shift of trauma-informed care in a child welfare practice context. The paper then explores aspects of trauma-informed care that may support newer ways of understanding experiences and interventions. Then, explores aspects of trauma-informed care that may …

Home Ec Babies At Saint Ben’S, Peggy L. Roske

Archives History Lessons

From the 1920s to the 1960s, a Home Management course offered by CSB’s Home Economics department involved giving students hands-on experience with child care by “borrowing” local infants to live with the students in a campus “house” setting for several weeks or months at a time.

Bryant University Undergraduate Course Catalog, 2024-2025, Bryant University

Bryant University Undergraduate Course Catalog

No abstract provided.

Happiness: It Starts With You And Your Mind, Alyssa Lagrone

Undergraduate Student Research Awards

No abstract provided.

Implementation Of A Non-Pharmacological Cognitive Stimulation Therapeutic Activities Protocol As A Delirium Prevention Method For Adults, Jada Hieb

Doctor of Nursing Practice (DNP) Practice Innovation Projects

Background/Purpose: Delirium is a complex clinical syndrome comprising a constellation of symptoms, including acute onset, inattention, altered level of consciousness, and disorganized thinking or cognitive dysfunction. Delirium is a common complication often unrecognized, expensive, and preventable. This project's focus was further exploring non-pharmacological delirium prevention strategies (NDPS).
Methods: A NDPS program using a therapeutic activity book (TAB) was implemented in a Midwestern acute care hospital measuring the impact on the number of positive delirium screens, the number of delirium diagnoses, and hospital length of stay (LOS).
Results: A causative relationship or association between the TAB and outcomes could not be …

Implementing The Teach-Back Method On Pessary Utilization In A Urogynecology Clinic, Marissa Eich

Doctor of Nursing Practice (DNP) Practice Innovation Projects

Background: The effectiveness of pessary patient education using the teach-back method and improving nurse confidence and conviction related to pessary use are essential in improving patient outcomes.
/="/">Local Problem: The current limitations in pessary education stem from constraints in nurse availability and workload distribution.
/="/">Methods: The quality improvement initiative involved conducting surveys to evaluate nurse confidence using surveys adapted from the Agency for Healthcare Research and Quality toolkit before the nurse education session, 1 month into the intervention, and at 3 months, when the implementation period ended. These surveys assessed the effectiveness of the teach-back method.
/="/">Intervention: …

The Additionality Double Standard, James Salzman, David Weisbach

Articles

Carbon offsets are widely criticized for lacking additionality. The public debate, how- ever, has failed to recognize that the problem of additionality goes far beyond offsets. It arises any time the government subsidizes an activity. Programs with longer histories than offsets and far more money at stake offer valuable lessons for managing lack of additionality in offsets. The article sets out the current efforts to prove offset additionality, explains why major gov- ernment programs present comparable additionality challenges, and show why other programs’ problems of additionality are perceived as significantly different than those for offsets. We examine the toolkit used …

The Natural Law Origins Of Private And Public Law, Richard Epstein

Articles

This article attempts to counter the widespread skepticism that surrounds any appeal to natural law principles, starting with Roman law at one end and the appeal to general law under Swift v. Tyson on the other. It steers a systematic middle course between moral absolutism, which treats all relationships as fixed and immutable, and modern realist positions that insist the infinite variety of legal approaches to most legal problems proves that there is no solid core to either natural law or general law. The natural law positions set out the basic relationships for marriage and family, for alluvion and avulsion …

The Trouble With Classifications, Aziz Huq

Articles

The Supreme Court relies increasingly on anticlassification rules to implement the Constitution’s various commands of evenhanded state treatment. These rules direct attention to whether an instance of a forbidden classification is present on the face of a challenged law. They contain two necessary steps. First, a court defines a general category of impermissible terms. Second, a court ascertains whether an instance of the category is found in enacted text—so triggering the familiar strict scrutiny analysis. So defined, anticlassification rules now dominate equal protection, free speech, “dormant” Commerce Clause, and even free exercise jurisprudence. The Roberts Court celebrates these doctrinal tests …

Free Speech On The Internet: The Crisis Of Epistemic Authority, Brian Leiter

Articles

No abstract provided.

Mir-379-5p Affects Breast Cancer Cell Behavior By Targeting Ube2e3 Ubiquitin Conjugating Enzyme, Araya K. Schroder, Conor J. Loy, Fernanda Aiala, Jazmyn Rafique, Arnob Ghosh, Lina I. Yoo

Faculty Publications

No abstract provided.

Oral Cancer Inequalities: Unmasking Health Disparities Of Vulnerable Populations In The U.S., Harold Nii-Aponsah

Graduate Research Theses & Dissertations

Oral health disparities remain a persistent and pressing public health issue in the United States, with access to dental care and outcomes disproportionately affected by socio-economic status, race, ethnicity, and insurance coverage. This three paper format dissertation highlights various aspects of disparities that do exist in oral health cancer incidence across the United States. The first paper utilizes data from the Surveillance, Epidemiology, and End Results (SEER) program to analyze 19,378 invasive Oral cavity and pharyngeal cancers (OCPC) cases diagnosed between 2018 and 2021, categorized by HPV status. Findings highlight that HPV-positive OCPCs are more prevalent among males, individuals aged …

Assistant, Parrot, Or Colonizing Loudspeaker? Chatgpt Metaphors For Developing Critical Ai Literacies, Anuj Gupta, Yasser Atef, Anna Mills, Maha Bali

Faculty Journal Articles

This study explores how discussing metaphors for AI can help build awareness of the frames that shape our understanding of AI systems, particularly large language models (LLMs) like ChatGPT. Given the pressing need to teach “critical AI literacy”, discussion of metaphor provides an opportunity for inquiry and dialogue with space for nuance, playfulness, and critique. Using a collaborative autoethnographic methodology, we analyzed metaphors from a range of sources, and reflected on them individually according to seven questions, then met and discussed our interpretations. We then analyzed how our reflections contributed to the three kinds of literacies delineated in Selber’s multiliteracies …

Modeling The Factors Influencing Secondary Students’ Performance In Stem Subjects, Nasser Mansour, Mustafa Çevik, Ali Yağci, Sarah Bader Mohsen Alotaibi, Heba El-Deghaidy

Faculty Journal Articles

STEM education plays a key role in influencing and orienting students’ interests towards STEM fields and careers. This influence is multifaceted, involving not only STEM content and experiences but also teachers, schools, and personal factors. The purpose of this study is to explore the factors impacting the academic performance of 951 tenth grade students in STEM subjects (physics, chemistry, biology, mathematics, and information technologies) who are attending public and private schools in two provinces of Turkey. Using a correlational research model, the study assessed how students’ personal characteristics, teacher effectiveness and school characteristics affect achievement in STEM courses. Data were …

Measurement Of Ascorbic Acid Samples' Optical Rotation Via An Improvised Polarimeter For Purity Assessment, Ryan Felicidario, Ramon M. Delos Santos

Physics Faculty Publications

The polarization of light finds practical application in physics and chemistry through the optical activity phenomenon, where polarimeters play a crucial role. This research builds on the improvised polarimeter designed by Kvittingen and Sjursnes, implemented with relevant modifications, to measure optical rotations of over-the-counter ascorbic acid samples. The study aims to assess the purity of two brands of ascorbic acid through polarimetry, comparing the calculated specific rotation with the literature values and supplementing the characterization with melting point determination. The constructed polarimeter, assembled using Lego bricks, provides an affordable alternative for educational purposes, addressing the challenges observed in the accessibility …