Digital Commons Network^™

Goose Grubbing And Warming Suppress Summer Net Ecosystem Co2 Uptake Differentially Across High-Arctic Tundra Habitats, Matteo Petit Bon, Karen H. Beard, Kari Anne Bråthen, Hanna Lee, Ingibjörg S. Jónsdóttir

Wildland Resources Faculty Publications

Environmental changes, such as climate warming and higher herbivory pressure, are altering the carbon balance of Arctic ecosystems; yet, how these drivers modify the carbon balance among different habitats remains uncertain. This hampers our ability to predict changes in the carbon sink strength of tundra ecosystems. We investigated how spring goose grubbing and summer warming—two key environmental-change drivers in the Arctic—alter CO₂ fluxes in three tundra habitats varying in soil moisture and plant-community composition. In a full-factorial experiment in high-Arctic Svalbard, we simulated grubbing and warming over two years and determined summer net ecosystem exchange (NEE) alongside its components: …

Intouch Week Of December 9, 2024, New York Medical College

InTouch

• NYMC Donors Make an Impact This Giving Tuesday
• Medical Students Inspire Youth During Black Men in White Coats Summit
• 29th Annual MSRF Set for December 13
• GSBMS Celebrates Friendsgiving
• NYMC Alumni/Student Fall Mixer Builds Connections and Professional Insights
• Human Milk for Extreme Preemies: A Kosher Option
• Artificial Intelligence Can Revolutionize Acute Stroke Care
• Design the Next NYMC T-Shirt
• NYMC and TU Hosts “Ninety Minutes: The Medical Magazine of the Web”
• In The Community: GSA 5K Raises Awareness for Food Insecurity, Fundraising Continues
• Faculty Spotlight: From Pupil to Professor: Alumni Lighting the Way at NYMC

Host Mediated Rhizobiome Engineering To Develop Locally Adapted Soil Mycorrhizal Inocula To Facilitate The Establishment Of Native Plants On Contaminated Soils, Anna Nugent

Graduate Theses & Non-Theses

The microbial community in the rhizosphere of plants plays an important role in plant establishment and survival, soil stability during stormwater runoff, and potential biofiltration of stormwater. Locally adapted fungal symbionts may further improve these outcomes for native plants at restoration sites. This study assesses the potential of host plant cultured, locally adapted soil mycorrhizal inocula to facilitate the establishment and growth of Mountain Big Sagebrush (Artemisia tridentata subsp. vaseyana) on heavy-metal contaminated soils. Soil was obtained from the rhizosphere of native plants at three sites in the West Side Soils Operable Unit of the Butte, Montana Superfund Complex. One …

National Parks For Future Generations?: The Covid-19 Pandemic’S Impacts On National Parks And Tourism, Colin Cummings '25

Student Research

This paper explores the complex relationship between tourism and the environment in U.S. National Parks, with a focus on the impact of the COVID-19 pandemic. It examines how increased visitation affects wildlife, the spread of invasive species, and the overall health of natural ecosystems. The author argues for a shift in public perception of national parks, emphasizing education, community engagement, and a deeper understanding of the interconnectedness of nature to ensure the preservation of these areas for future generations. The paper also discusses the role of park rangers and historical interpretations of wildlife and the environment, as well as the …

Personal Legacies Of The American Empire: Witnessing The Rise Of A Western Power In The Philippines, Christian S. Condo Gilkes '25

Student Research

This historical study examines the Philippine-American War through the personal experiences of four individuals: David Fagen, a Black-American soldier who joined the Filipino resistance; Datu Ali, a Moro chieftain; George W. Suriley, an American soldier; and Apolinario Mabini, an advisor to Aguinaldo and a Filipino revolutionary. The paper explores the complex motivations, beliefs, and perspectives of individuals on both sides of the conflict, shedding light on the human cost of American imperialism and the diverse reactions to the United States' expansion into the Philippines. It further examines the racial and social dynamics within the U.S. military and the experiences of …

Mems 411: Timed Mosquito Egg Container Design Project, Paige Warren, Witt Ciesla, Ethan Sobel

Mechanical Engineering Design Project Class

The goal of this project is to design and construct a device that allows for the controlled study of mosquito egg-laying behavior in response to artificial light and temperature variations. Specifically, the device will limit access to cups of standing water, which serve as egg-laying sites, to preprogrammed times of day over a 7-day period.
The device should ensure the following:

• Control Access: The container should be open and closed at predetermined intervals, allowing mosquitoes to access the cups of standing water only during these times.
• Programmability: It should be easy for a novice to specify the opening and closing …

Na2B12Si6Se18: A Novel B12-Cluster-Containing Quaternary Selenoborate Framework Material, Gopabandhu Panigrahi, Hunter B. Tisdale, Gregory Morrison, Hans Conrad Zur Loye

Faculty Publications

We report the successful synthesis of the new quaternary, three-dimensional Na₂B₁₂Si₆Se₁₈ material using a solid-state synthesis route. This compound is characterized by a unique framework structure that features the rare icosahedral [B₁₂]¹⁰⁺ cation which is connected via Si2Se6 polyhedral units into a 3D framework structure with Na+ ions located inside the channels. The Na₂B₁₂Si₆Se₁₈ compound crystallizes in the cubic crystal system in the space group Im, with lattice parameter a = 11.91110(10) Å and unit cell volume of 1689.88(4) ų. …

Mems 411: Hydroponic Gardening System, Tiger Lu, Aj Shanahan, Jaquelin Guzman, Brandon Lacy

Mechanical Engineering Design Project Class

This report summarizes the engineering design process undertaken for the development of a hydroponic gardening system. The project began with selecting a concept, as a team, we decided to focus on designing a system tailored to community gardening needs. The report is organized into five main sections: Problem Understanding, Concept Generation, Concept Selection, Concept Embodiment, and Design Refinement. In the Problem Understanding phase, the team conducted extensive research on patents, codes and standards, user needs, design metrics, and project management. This foundational research was critical to ensure all aspects were considered before beginning the building process. User needs were identified …

Enhancement Of Ambient Air Quality Index Forecasting Using Optimized Ensemble Model, Vanitha M

Theses and Dissertations

Forecasting ambient air quality is essential for environmental sustainability and public health, especially in heavily populated regions such as China, India, and the United States where air pollution remains a serious concern. Traditional forecasting models often struggle to accurately represent air quality data because of its complex patterns and nonlinear interactions. To address these challenges and improve forecast performance, this research proposes a comprehensive strategy that integrates parallel heterogeneous ensemble modeling with Bayesian optimization.

The study begins with a seasonal machine learning–based imputation technique (SeasonalMLImpute) designed to handle missing data in meteorological and air quality parameters. This method is evaluated …

Recovering Phosphorus And Nitrogen From Leachate Collected From Chidaya Sanitary Landfill Dodoma Tanzania For Fertilizer Production, Yasin Y. Kifwe, Godlisten N. Shao, Washa B. Washa, Christina F. Pius

Tanzania Journal of Science

The demand for fertilizer is a global issue that poses a significant threat to future food security. Tanzania is among the countries which rely on agriculture for food production and contribute largely to the economy of the nation. However, farmers incur high production costs due to the utilization of expensive and environmentally insecure fertilizers. The present study investigated the potential of recovering nitrogen and phosphorus nutrients from leachate to produce fertilizer. Hanna pH meter (HI-98121) was used to determine the pH of leachate which was found to be 8.29 ± 0.33. The concentration of phosphorus and nitrogen was determined by …

Itaconate Transporter Slc13a3 Impairs Tumor Immunity Via Endowing Ferroptosis Resistance, Heng Lin, Kole Tison, Yuheng Du, Paul Kirchhoff, Chan Kim, Weichao Wang, Hannah Yang, Michael Pitter, Jiali Yu, Peng Liao, Jiajia Zhou, Linda Vatan, Sara Grove, Shuang Wei, Thomas Vigil, Yatrik M Shah, Richard Mortensen, Ilona Kryczek, Lana Garmire, Jwala P Sivaccumar, Ashwin Kumar Ramesh, Ningyan Zhang, Zhiqiang An, Shaomeng Wang, Weiping Zou

The Brown Foundation: Institute of Molecular Medicine

Immune checkpoint blockade (ICB) triggers tumor ferroptosis. However, most patients are unresponsive to ICB. Tumors might evade ferroptosis in the tumor microenvironment (TME). Here, we discover SLC13A3 is an itaconate transporter in tumor cells and endows tumor ferroptosis resistance, diminishing tumor immunity and ICB efficacy. Mechanistically, tumor cells uptake itaconate via SLC13A3 from tumor-associated macrophages (TAMs), thereby activating the NRF2-SLC7A11 pathway and escaping from immune-mediated ferroptosis. Structural modeling and molecular docking analysis identify a functional inhibitor for SLC13A3 (SLC13A3i). Deletion of ACOD1 (an essential enzyme for itaconate synthesis) in macrophages, genetic ablation of SLC13A3 in tumors, or treatment with SLC13A3i …

Deciphering Immune Suppression Mechanisms Of Primary And Metastatic Breast Cancer, Seunghyun Lee

Arts & Sciences Graduate Student Theses and Dissertations

Immune checkpoint blockade (ICB) has revolutionized cancer treatment, receiving FDA approval for various previously incurable cancers. In breast cancer, the combination of pembrolizumab (an anti-PD-1 antibody) with chemotherapy has become the standard-of-care for early-stage (Keynote-522) and advance-stage (Keynote-355) triple-negative breast cancer (TNBC). Unfortunately, over 30% of TNBC patients fail to respond to the combined chemo-immune therapy treatment, and the causes are unknown. Furthermore, ICB has demonstrated poor results in hormone-receptor positive breast cancer. While it is well-established that breast cancer cells can evade immune responses, the specific mechanisms driving immune evasion remain unclear. Thus, deciphering the immune system's role in …

Association Of Unmet Social Needs With Disease-Related Outcomes In Pediatric Patients With Sickle Cell Disease, Molly Sonenklar, Sarah Marks, Cerelia Donald, Cecelia Valrie, Wally Smith, India Sisler

School of Medicine Faculty Publications

Background: Social determinants of health (SDoH) are socioeconomic factors that influence health and well-being, though when unmet can greatly contribute to health disparities. Individuals with sickle cell disease (SCD) are at increased risk of mortality, disability, and healthcare utilization. However, there are limited data linking specific social needs with disease outcomes in this population. Therefore, we sought to identify the unmet needs in one institution and their association with healthcare utilization. Methods: Children with SCD and their guardians answered demographic and SDoH questionnaires during routine Sickle Cell Clinic appointments. We defined an unmet social need as any positive answer to …

Development Of A Rapid Method For Pfas Detection And Quantitation In Human Hair, Justin M. Allen

Student Theses

In recent years, per- and polyfluoroalkyl substances (PFAS) have emerged as a critical focus in environmental and public health research due to their persistent nature and widespread use in products ranging from non-stick cookware to firefighting foams. These "forever chemicals" resist degradation, posing significant ecological and human health risks. While extensive studies have explored PFAS in environmental matrices, research into their presence in human hair remains limited, with only a handful of studies addressing this biomarker's potential. This thesis aims to develop a robust analytical method for detecting PFAS in human hair, leveraging its unique properties to provide a long-term …

Antibiotic Resistance Of Laboratory E. Coli Strains, Alexis H. Hart

Honors Projects

Antibiotic resistance is an ongoing global health crisis. The prevalence and distribution of antibiotic resistance in environmental microbial communities have become climactic areas of investigation due to their far-reaching implications for ecosystem health, human well-being, and the sustainability of antimicrobial efficacy.

Adipocyte-Derived Small Extracellular Vesicles Exacerbate Diabetic Ischemic Heart Injury By Promoting Oxidative Stress And Mitochondrial-Mediated Cardiomyocyte Apoptosis, Lu Gan, Jianli Zhao, Peng Yao, Theodore A. Christopher, Bernard Lopez, Wayne B. Lau, Walter Koch, Erhe Gao, Xin-Liang Ma, Yajing Wang

Department of Emergency Medicine Faculty Papers

BACKGROUND: Diabetes increases ischemic heart injury via incompletely understood mechanisms. We recently reported that diabetic adipocytes-derived small extracellular vesicles (sEV) exacerbate myocardial reperfusion (MI/R) injury by promoting cardiomyocyte apoptosis. Combining in vitro mechanistic investigation and in vivo proof-concept demonstration, we determined the underlying molecular mechanism responsible for diabetic sEV-induced cardiomyocyte apoptosis after MI/R.

METHODS AND RESULTS: Adult mice were fed a high-fat diet (HFD) for 12 weeks. sEV were isolated from plasma or epididymal adipose tissue. HFD significantly increased the number and size of plasma- and adipocyte-derived sEV. Intramyocardial injection of an equal number of diabetic plasma sEV in nondiabetic …

Making A Career Out Of Teaching: Exploring Longevity And Resiliency In Tennessee School-Based Agriculture Teachers, S. Sirrena Wiggins, Blake C. Colclasure, Tyler Granberry, Christopher T. Stripling

Journal of Research in Technical Careers

The need for qualified school-based agricultural education (SBAE) teachers is often discussed in terms of teacher recruitment; however, retaining those teachers is also necessary to ensure the stability and longevity of SBAE programming. Through the lens of teacher resilience, this qualitative study sought to answer the question: What individual and social-ecological characteristics of Tennessee career agriculture teachers contributed to their resiliency and longevity in the profession? In response, we conducted a phenomenological study of Tennessee agriculture teachers with 15 or more years in the profession. After coding data from 15 interviews, six themes emerged: (1) Passion, (2) Support, (3) Adaptability, …

Wearable Surface Electromyography System To Predict Freeze Of Gait In Parkinson's Disease Patients., Anna Moore, Jinxing Li, Christopher H Contag, Luke J Currano, Connor O Pyles, David A Hinkle, Vivek Shinde Patil

Neuroscience Articles

Freezing of gait (FOG) is a disabling yet poorly understood paroxysmal gait disorder affecting the vast majority of patients with Parkinson's disease (PD) as they reach advanced stages of the disorder. Falling is one of the most disabling consequences of a FOG episode; it often results in injury and a future fear of falling, leading to diminished social engagement, a reduction in general fitness, loss of independence, and degradation of overall quality of life. Currently, there is no robust or reliable treatment against FOG in PD. In the absence of reliable and effective treatment for Parkinson's disease, alleviating the consequences …

Mae Enewsbrief July-Sept 2024, Department Of Mechanical And Aerospce Engineering, Michigan Technological University

Department of Mechanical and Aerospace Engineering eNewsBrief

No abstract provided.

The Spectrum Of Cutaneous Manifestations In Covid-19 Patients At Dr. Cipto Mangunkusumo Hospital, Sandra Widaty, Sri Linuwih Susetyo Wardhani Menaldi, Eliza Miranda, Melani Marissa, Hanny Nilasari, Thong Felicia Melinda, Emilina Faradila Cornain

Journal of General - Procedural Dermatology and Venereology Indonesia

Background: Cutaneous manifestations are identified in 0.2%–20% of COVID-19 cases, both in adult and pediatric patients. They can occur before, simultaneously with, or after the systemic symptoms of COVID-19. This study aims to analyze the association between cutaneous manifestations, severity, and outcomes of patients with COVID-19.

Methods: This observational study was conducted from April 2020 to April 2021 in Dr. Cipto Mangunkusumo Hospital, a referral center for COVID-19 in Jakarta, Indonesia. Medical records were used to collect demographic, clinical, and laboratory data.

Results: A total of 0.61% (31/5070) of COVID-19 cases showed cutaneous manifestations, consisting of maculopapular (80.6%), vesicular …

Four Iwu Students Receive Funding To Develop Ideas Through Titan New Venture Challenge, Jeffery Woodard

News and Events (Discontinued Series)

No abstract provided.

The Relationship Between Religious Coping Styles And Eating Disorder Risk In Christians In A University Setting, Meghan E. Aubuchon

Honors Theses

Existing research on eating disorders and religion is beginning to gain momentum in the present day, but research is lacking on the topic of religious coping and eating disorder risk. This study aimed to investigate the relationship between two known styles of religious coping—positive and negative—and eating disorder risk in University of Mississippi students, faculty, and staff who identify as Christian. A survey consisting of basic demographic questions, the EAT-26, and the Brief RCOPE was distributed via emails sent by the office of IREP to students, faculty, and staff at the University of Mississippi. A total of 330 participants were …

Rare Breast Cancers Review, Bowen Song, Harnoor Singh

Faculty, Staff and Student Publications

Background/objectives: Breast cancer is one of the most common malignancies in women, with rare subtypes presenting unique clinical challenges. This review provides a comprehensive analysis of rare breast cancers, including both epithelial and non-epithelial subtypes, and explores their epidemiology, pathology, prognosis, and treatment approaches.

Methods: A systematic review was conducted focusing on recent advancements in the treatment of rare breast cancer subtypes. Articles were selected based on criteria emphasizing studies from the past five years, with older foundational studies included where necessary. The analysis incorporated molecular profiling, clinical trials, and advancements in targeted and immunotherapies, where possible.

Results: Rare epithelial …

Rechovos Estates Llc. V. Thomas

All Decisions

In this licensee holdover proceeding, the court dismissed the petition and found that the tenant, the son of the deceased tenant of record, had proven his entitlement to succeed to the rent-stabilized tenancy. The court found that the tenant's documentary evidence and testimony, including bank statements, utility bills, and identification documents, outweighed the landlord's testimony that he had never observed the tenant residing in the apartment. The court also rejected the landlord's argument that the tenant's omission from the deceased tenant's SCRIE application precluded his succession claim.

Agronomic Biofortification Of Calcium In Pak Choy (Brassica Rapa Subsp. Chinensis) Via Hydroponic Nutrient Film Technique, Regina Septiani Zahro, Khavid Faozi, Zulfa Ulinnuha, Agus Sarjito

Jurnal Kultivasi

Pak choy is rich in calcium, magnesium, phosphorus, iron, and vitamin K, all essential for health. Pak choy requires a proper balance of nutrients for optimal growth. In a hydroponic system, any imbalance in nutrient levels can negatively impact plant growth and reduce the nutritional value stored in the tissues. Selecting suitable varieties and providing appropriate calcium treatment can help increase calcium content and enhance productivity. This study aims to determine the effect of calcium concentration on growth, yield, and Ca content and the most responsive varieties to increased calcium concentration. The research design used was a Split Plot Design …

Potential Propagation Seedling Of Ramie (Boehmeria Nivea) From Various Types Of Stem Cuttings, Taufiq Hidayat Rahman Side, Mayasari Yamin, Sri Mulyani, Agung Pangestu Aji, Luthfi Ayunawati

Jurnal Kultivasi

Ramie is a fiber-producing plant that can replace cotton as a raw material for the textile industry. In general, ramie plants are reproduced using rhizomes, but it takes a long time, around two years, to be used as a source of planting material. Therefore, other sources of explants besides rhizomes are required, such as stem cuttings. Explants from stem cuttings are quickly available and only need 2-3 months to be used as planting material. This study aims to determine the potential of effective stem cuttings that can be used as planting material for the propagation of ramie seedlings. The research …

How Should Scientists Act? Assessing Public Perceptions Of Scientists And Scientific Practices And Their Implications For Science Communication, Thomas G. Safford, Emily H. Whitmore

Faculty Publications

Is how science is conducted legitimate? Are scientists trustworthy? Whether the public answers “yes” to these questions is critical for science communicators. We explore how social factors affect public perceptions of the practice of science, and then test how those beliefs relate to views about how scientists engage with the public and policy making. Our results show that political ideology and religiosity affect these views. However, more importantly, respondents’ concerns about the integrity of the scientific process are the strongest predictor of views about scientists’ behavior, providing a focus area for future communication efforts in support of science-based decision making.

The Role Of Dna Topoisomerases In The Completion Of Dna Replication, Parisa Mokhtari

Dissertations and Theses

Accurate replication of the genome is essential to maintain cellular life. Completing DNA replication on the chromosome is central to this task and involves several enzymes, including RecBCD, RecG and SbcCD-ExoI, which process, join, and resolve the two convergent replication forks. This event is certain to generate a number of structural complexities involving supercoiling, tangles and knots as the two DNA replication forks converge which must be resolved to maintain the integrity of the genome. Structural knots and tangles generated during DNA replication, transcription and segregation are typically resolved by DNA topoisomerases. E. coli encodes four DNA topoisomerases--two type I …

Additional Expression Of T-Cell Engager In Clinically Tested Oncolytic Adeno-Immunotherapy Redirects Tumor-Infiltrated, Irrelevant T Cells Against Cancer Cells To Enhance Antitumor Immunity, Daisuke Morita, Amanda Rosewell Shaw, Greyson Biegert, Caroline Porter, Mae Woods, Spyridoula Vasileiou, Bora Lim, Masataka Suzuki

Faculty, Staff and Student Publications

Background: Oncolytic adenoviruses (OAds) are the most clinically tested viral vectors for solid tumors. However, most clinically tested "Armed" OAds show limited antitumor effects in patients with various solid tumors even with increased dosages and multiple injections. We developed a binary oncolytic/helper-dependent adenovirus system (CAdVEC), in which tumors are coinfected with an OAd and a non-replicating helper-dependent Ad (HDAd). We recently demonstrated that a single low-dose CAdVEC expressing interleukin-12, programmed death-ligand 1 blocker, and HSV thymidine kinase safety switch (CAdTrio) induces significant antitumor effects in patients, including complete response. Similar to previous OAd studies, all patients primarily amplified Ad-specific T …

Mountain Big Sagebrush Restoration In Former Dryland Pasture, Elizabeth Bailey, Eric Thacker, Thomas Monaco, Kari E. Veblen

All Current Publications

Our study supports using older naturally grown sagebrush plants (wildlings) for restoration efforts. Wildlings had already faced various environmental stresses before transplantation and then had a survival advantage when transplanted. Our study also demonstrates how successfully established transplants planted in “islands” aid in the future recruitment of sagebrush. Overall, because of their higher survival, we found that wildlings led to higher sagebrush densities and were a more cost-effective approach.