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Articles 98731 - 98760 of 100962
Full-Text Articles in Entire DC Network
Enhanced Prediction Of Stock Markets Using A Novel Deep Learning Model Plstm-Tal In Urbanized Smart Cities, Saima Latif, Nadeem Javaid, Faheem Aslam, Abdulaziz Aldegheishem, Nabil Alrajeh, Safdar Hussain Bouk
Enhanced Prediction Of Stock Markets Using A Novel Deep Learning Model Plstm-Tal In Urbanized Smart Cities, Saima Latif, Nadeem Javaid, Faheem Aslam, Abdulaziz Aldegheishem, Nabil Alrajeh, Safdar Hussain Bouk
School of Cybersecurity Faculty Publications
Accurate predictions of stock markets are important for investors and other stakeholders of the equity markets to formulate profitable investment strategies. The improved accuracy of a prediction model even with a slight margin can translate into considerable monetary returns. However, the stock markets' prediction is regarded as an intricate research problem for the noise, complexity and volatility of the stocks' data. In recent years, the deep learning models have been successful in providing robust forecasts for sequential data. We propose a novel deep learning-based hybrid classification model by combining peephole LSTM with temporal attention layer (TAL) to accurately predict the …
Traumatic Brain Injury And Public Stigma: The Effect Of Perceived Responsibility, Mackenzie Grenko
Traumatic Brain Injury And Public Stigma: The Effect Of Perceived Responsibility, Mackenzie Grenko
Dissertations and Theses @ UNI
No abstract provided.
An Exploratory Study Of Research Contexts For Information Literacy Instruction, Allison Hosier
An Exploratory Study Of Research Contexts For Information Literacy Instruction, Allison Hosier
University Libraries Faculty Scholarship
In a previous study, the author argued that information literacy instruction which takes into account the contextual nature of research is more meaningful to students and has more potential for long term impact than instruction that focuses narrowly on academic research skills. As part of that argument, the author identified six types of research that represented the contextual nature of research—academic, creative, personal, professional, scholarly, and scientific. This list of research types has since proven useful in the classroom. However, it is still an open question whether this framework is a useful way of thinking about research. The author set …
Artificial Intelligence And Lis Publishing: A Survey Of Journal Editors, Allison Hosier, Laureen Cantwell-Jurkovic
Artificial Intelligence And Lis Publishing: A Survey Of Journal Editors, Allison Hosier, Laureen Cantwell-Jurkovic
University Libraries Faculty Scholarship
This Qualtrics-based survey was used to explore the AI-related policies of LIS journals and various journal support mechanisms about AI (e.g., AI detection tools, peer reviewer guidelines, copyediting processes, and more), as well as EIC perspectives and attitudes toward generative AI within the context of scholarly publishing. In early summer 2024, researchers shared the survey with select top-tier journal editors in the library science field. Results from this survey will be published in the article “Artificial Intelligence and LIS Publishing: A Survey of Journal Editors” in Library Trends in 2025 (Volume 73). These findings contribute to a larger conversation about …
Editorial: Invasive Pathogens And Arthropods: Biogeography, Drivers Of Invasion Success, Impacts On Indigenous Forest Trees And Emerging Management Strategies, Frank Chidawanyika, Komivi S. Akutse, Tendai Musvuugwa, Abdullahi A. Yusuf, Casper Nyamukondiwa
Editorial: Invasive Pathogens And Arthropods: Biogeography, Drivers Of Invasion Success, Impacts On Indigenous Forest Trees And Emerging Management Strategies, Frank Chidawanyika, Komivi S. Akutse, Tendai Musvuugwa, Abdullahi A. Yusuf, Casper Nyamukondiwa
All Peer-Reviewed Publications
With the ongoing global anthropogenic climate change, a silent war rages in forests, the lungs of the earth. Invasive pathogens and insect pests are decimating native trees, compromising ecological function, biodiversity, and ecosystem services. Many of the processes surrounding successful biotic invasions are broad and have been previously analyzed (Hobbs et al., 2006; Blackburn et al., 2011). For invasive insect pests and pathogens, globalization, the rise in human population and associated environmental disturbances are recognized as fundamental drivers of introduction of propagules of non-native species to novel environments. Superior tolerance of extreme climate environments, in particular temperature, is also associated …
Pleasures And Politics: Moving Towards A Feminist Performance Practice, Delaney Burke
Pleasures And Politics: Moving Towards A Feminist Performance Practice, Delaney Burke
Theses : Honours
The focus of this research is the use of the female body as a tool for developing a feminist performance practice. This research interrogated the use of neo-burlesque and erotic dance in contemporary postdramatic performance. Contemporary feminist performance artists, such as Emma Maye Gibson (aka Betty Grumble), often use the female body as a tool for entertainment and political statement, and this trend parallels an increase of women moving into the burlesque and erotic dance spheres as professional performers and hobbyists. Despite this suggestion that the female body is a fertile site for feminist action and statement, its use is …
The Early String Chamber Music Of Agnes Zimmermann, Miranda Dyskin
The Early String Chamber Music Of Agnes Zimmermann, Miranda Dyskin
Theses : Honours
This dissertation focusses on the early string chamber music of German-English composer and pianist Agnes Zimmermann (1847-1925), written whilst she was a student at the Royal Academy of Music in London. Whilst almost unknown today, Zimmermann was one of the finest pianists of the late[1]Nineteenth Century, appearing throughout Europe both as a concerto soloist and as a distinguished chamber music collaborator. She was also an accomplished composer, writing piano pieces, songs, music for the church and, especially, chamber music. Her models were the great Germanic figures of the Nineteenth Century, especially Beethoven, Schubert, Mendelssohn and Brahms.
This dissertation examines two …
Steve Grossman, The Catalyst: A Practice-Led Research Investigation Into Developing A Chromatic Approach To Improvisation, Joshua Parker
Steve Grossman, The Catalyst: A Practice-Led Research Investigation Into Developing A Chromatic Approach To Improvisation, Joshua Parker
Theses : Honours
Steve Grossman was a tenor saxophonist from Brooklyn, New York, who passed away in 2020, leaving a catalogue of recordings and improvisations that are largely overlooked and under-appreciated by the mainstream jazz culture. Inspired heavily by the modal and free jazz improvisations of John Coltrane during his later period (which heavily utilised a chromatic approach to generate intensity), Grossman developed his own unique and powerful approach to the post-Coltrane style. This voice began to solidify from a young age, as is evident on recordings during the 1970s, such as Miles Davis’ Black Beauty Live at Fillmore West (1973) and Live …
From Pedestal To Power, From Floating Fairies To Feminine Fury: How The Portrayal Of Women In Contemporary Performance Work Reflects Changes And The Lack Thereof In Societal Perceptions Of Women In The 21st Century, Lillany Weber
Theses : Honours
Dance can stand as a social commentary that can improve and progress social and societal development, positively impacting society, widely held views and the world. The research examines shifting gender perceptions in feminist dance practices, delving into how the portrayal of women in contemporary dance performance reflects changes and the lack thereof in societal perceptions of women in the 21st century. Given the extreme complexity of the modern world, this project seeks to build on past research to bring relevant exploration into today’s context. Utilising a qualitative case study analysis of 2023 work Body Body Commodity by Australian choreographer Jenni …
Integrating The Patient’S Voice Into The Research Agenda For Treatment Of Chemosensory Disorders, Claire Murphy, Pamela Dalton, Katie Boateng, Stephanie Hunter, Pamela Silberman, Jenifer Trachtman, Suz Schrandt, Bita Naimi, Emily Garvey, Paule Joseph, Conner Frank, Abigail Albertazzi, Gurston Nyquist, Nancy Rawson
Integrating The Patient’S Voice Into The Research Agenda For Treatment Of Chemosensory Disorders, Claire Murphy, Pamela Dalton, Katie Boateng, Stephanie Hunter, Pamela Silberman, Jenifer Trachtman, Suz Schrandt, Bita Naimi, Emily Garvey, Paule Joseph, Conner Frank, Abigail Albertazzi, Gurston Nyquist, Nancy Rawson
Department of Otolaryngology - Head and Neck Surgery Faculty Papers
World-wide some 658 million people were infected with coronavirus disease 2019 (COVID-19) and millions suffer from chemosensory impairment associated with long COVID. Current treatments for taste and smell disorders are limited. Involving patients has the potential to catalyze the dynamic exchange and development of new ideas and approaches to facilitate biomedical research and therapeutics. We assessed patients' perceptions of the efficacy of treatments for chemosensory impairment using an online questionnaire completed by 5,815 people in the US Logistic regression determined variables predictive of reported treatment efficacy for patients aged 18 to 24, 25 to 39, 40 to 60, and 60+ …
Wholistic Healing: Challenges And Opportunities For The Church, Anna Galeniece
Wholistic Healing: Challenges And Opportunities For The Church, Anna Galeniece
All Books
Edited by Anna M. Galeniece
Influence Of Electrospinning Parameters On The Morphology Of Electrospun Poly(3-Hydroxybutyrate-Co-3-Hydroxyvalerate) Fibrous Membranes And Their Application As Potential Air Filtration Materials, Yaohui Liu, Xiaoying Lu
Influence Of Electrospinning Parameters On The Morphology Of Electrospun Poly(3-Hydroxybutyrate-Co-3-Hydroxyvalerate) Fibrous Membranes And Their Application As Potential Air Filtration Materials, Yaohui Liu, Xiaoying Lu
Department of Construction, Environment and Engineering
A large number of non-degradable materials have severely damaged the ecological environment. Now, people are increasingly pursuing the use of environmentally friendly materials to replace traditional chemical materials. Polyhydroxyalkonates (PHAs) are receiving increasing attention because of the unique biodegradability and biocompatibility they offer. However, the applications of PHAs are still limited due to high production costs and insufficient study. This project examines the optimal electrospinning parameters for the production of PHA-based fibrous membranes for air filtration. A common biodegradable polyester, Poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV), was electrospun into a nanofibrous membrane with a well-controlled surface microstructure. In order to produce smooth, bead-free fibers …
Characterization Of 3d Printed Poly(3-Hydroxybutyric-Co-3-Hydroxyvalerate) By Fused Granular Fabrication Through Thermal And Mechanical Analyses Lok-, Yaohui Liu
Department of Construction, Environment and Engineering
Poly[R-3-hydroxybutyrate-co-(R-3-hydroxyvalerate)] (PHBVs) copolymers are promising biopolymers, which could substitute petroleum-based plastics for various applications. PHB and PHBV pellets were processed on a customized 3D printer via Fused Granular Manufacturing (FGM) approach modified with a Mahor screw extruder. To anticipate the behaviour of PHBVs when transformed using conventional thermo-mechanical shaping processes, thermal and mechanical analyses were carried out in order to better understand the effect of annealing temperature on their crystallization behaviour and mechanical properties of PHB polymer and PHBV copolymer. The objectives of the present work were to propose an experimental strategy to study the melting and crystallization events, crystalline …
Full Tailored Metal Content Ncm Regeneration From Spent Lithium-Ion Battery Mixture Under Mild Condition, Chi Wing, Alex Tsang
Full Tailored Metal Content Ncm Regeneration From Spent Lithium-Ion Battery Mixture Under Mild Condition, Chi Wing, Alex Tsang
Department of Construction, Environment and Engineering
Mild conditioned, second-life ternary nickel–cobalt–manganese (NCM) black powder regeneration from spent lithium-ion batteries’ (LIBs) black powder mixture was demonstrated after mild conditioned p-toluenesulphuric acid (PTA)-assisted wet leaching. The NCM ratio was tailored to several combinations (333, 523, 532, and 622) by adding a suitable amount of metal (Ni, Co, Mn)-sulphate salt to the leachate. Regenerated NCM was obtained by co-precipitation with sodium hydroxide pellets and ammonia pH buffering solution, followed by lithium (Li) sintering under ambient air and size sieving. The obtained regenerated NCM powder was used for the energy storage materials (ESM) in coin cell (Li half-cell, CR2032) evaluation. …
Study Of Microalgae Biofixation With Bacteria Carbonic Anhydrase For Carbon Capture And Utilization, Chan Cho Yin
Study Of Microalgae Biofixation With Bacteria Carbonic Anhydrase For Carbon Capture And Utilization, Chan Cho Yin
Department of Construction, Environment and Engineering
Climate change has been significantly affecting human activities due to the accumulation of greenhouse gases, such as carbon dioxide. Biofixation of carbon dioxide (CO2) has been investigated to reduce the atmospheric CO2 level and slow the rapid increase in the global temperature. Carbon capture and utilization (CCU) can be performed by either physio-chemical or biological methods. The latter takes place in ambient temperature and mild conditions, such that there is no need for high pressure and high energy consumption nor hazardous chemicals. Biofixation by microalgae has been utilized to capture CO2 and the microalgae biomass collected after the process can …
Plant-Parasitic Nematodes Associated With Maize, And Their Relationship With Soil Properties In Southern And Southwestern Ethiopia, Abebe W. Aseffa, Beira H. Meressa, Tadele Tefera, Kristina K. Green, Peter Anderson, Esayas Mendesil
Plant-Parasitic Nematodes Associated With Maize, And Their Relationship With Soil Properties In Southern And Southwestern Ethiopia, Abebe W. Aseffa, Beira H. Meressa, Tadele Tefera, Kristina K. Green, Peter Anderson, Esayas Mendesil
All Peer-Reviewed Publications
Maize is an important cereal crop in sub-Saharan Africa (SSA). Plant-parasitic nematodes significantly impact maize production. However, research on maize nematodes in SSA is limited. The current study aimed to assess the occurrences and densities of nematodes associated with maize and to assess the correlation of some soil physicochemical properties with nematodes in southern and southwestern Ethiopia. One hundred and eighty-six soil and root samples were collected from 62 maize fields (31 from Hawassa Zuria and 31 from Mana districts). Eleven plant-parasitic nematode genera were identified. The most important genera of plant-parasitic nematodes identified were Meloidogyne and Pratylenchus, followed by …
Characterisation Of ‘Giant’ Cysts Of The Potato Cyst Nematode, Globodera Rostochiensis, Present In Potato Fields In Kenya, James A. Price, Kelsey Hunt, Newton Nyagah, Calvince Orage, Onesmus Mwaura, Solveig Haukeland, Danny Coyne, John T. Jones
Characterisation Of ‘Giant’ Cysts Of The Potato Cyst Nematode, Globodera Rostochiensis, Present In Potato Fields In Kenya, James A. Price, Kelsey Hunt, Newton Nyagah, Calvince Orage, Onesmus Mwaura, Solveig Haukeland, Danny Coyne, John T. Jones
All Peer-Reviewed Publications
Potato production in East Africa is seriously impacted by the potato cyst nematode (PCN), Globodera rostochiensis, where it has been recorded in at least three countries. In Kenya, it is widespread in all major potato-growing regions, often at very high densities. Consecutive cropping of potato on the same land and a sub-tropical climate have influenced PCN biology. For example, unusually large cysts have been regularly recovered. We have analysed the biological properties of these ‘giant cysts’. The giant cysts contained more eggs than those recovered from UK fields. Egg size did not differ from UK populations and there was no …
A Convolutional Neural Network With Image And Numerical Data To Improve Farming Of Edible Crickets As A Source Of Food—A Decision Support System, Henry Kyalo, Henri E.Z. Tonnang, James P. Egonyu, John Olukuru, Chrysantus M. Tanga, Kennedy Senagi
A Convolutional Neural Network With Image And Numerical Data To Improve Farming Of Edible Crickets As A Source Of Food—A Decision Support System, Henry Kyalo, Henri E.Z. Tonnang, James P. Egonyu, John Olukuru, Chrysantus M. Tanga, Kennedy Senagi
All Peer-Reviewed Publications
Crickets (Gryllus bimaculatus) produce sounds as a natural means to communicate and convey various behaviors and activities, including mating, feeding, aggression, distress, and more. These vocalizations are intricately linked to prevailing environmental conditions such as temperature and humidity. By accurately monitoring, identifying, and appropriately addressing these behaviors and activities, the farming and production of crickets can be enhanced. This research implemented a decision support system that leverages machine learning (ML) algorithms to decode and classify cricket songs, along with their associated key weather variables (temperature and humidity). Videos capturing cricket behavior and weather variables were recorded. From these videos, sound …
The Experiences Of Older Immigrants Living With Dementia In Australia: A Multi-Method Secondary Analysis, Pelden Chejor
The Experiences Of Older Immigrants Living With Dementia In Australia: A Multi-Method Secondary Analysis, Pelden Chejor
Theses: Doctorates and Masters
The ageing immigrant population and rising dementia cases underscores the need for culturally appropriate dementia care services. However, accessing dementia care services can be challenging for immigrants due to cultural and linguistical differences including their health beliefs. Understanding the experiences and concerns of older immigrants living with dementia is imperative for the planning and delivery of culturally and linguistically appropriate care. The aim of this thesis was to explore and describe the experiences of older immigrants living with dementia, as well as to describe and compare (against non-immigrants living with dementia) the characteristics (neuropsychiatric symptoms and pain characteristics) of older …
Foreign In Two Homelands, Michelle Lynn Kahn
Foreign In Two Homelands, Michelle Lynn Kahn
Bookshelf
What happens when migrants are rejected by the host society that first invited them? How do they return to a homeland that considers them outsiders? Foreign in Two Homelands explores the transnational history of Turkish migrants, Germany’s largest ethnic minority, who arrived as “guest workers” (Gastarbeiter) between 1961 and 1973. By the 1980s, amid rising racism, neo-Nazis and ordinary Germans blamed Turks for unemployment, criticized their Muslim faith, and argued they could never integrate. In 1983, policymakers enacted a controversial law: paying Turks to leave. Thus commenced one of modern Europe’s largest and fastest waves of remigration: within one year, …
A Process Evaluation Of A Program Designed To Expand Access To The Iowa Supplemental Nutrition Assistance Program-Education (Snap-Ed), Justine R. Hoover
A Process Evaluation Of A Program Designed To Expand Access To The Iowa Supplemental Nutrition Assistance Program-Education (Snap-Ed), Justine R. Hoover
Dissertations and Theses @ UNI
The Iowa State University (ISU) Extension and Outreach Supplemental Nutrition Assistance Program – Education (SNAP-Ed), implements food- and nutrition-related interventions through direct nutrition education and Policy, Systems, and Environment (PSE) changes. The target audience for these interventions is Iowans with low-income who are eligible or likely eligible for the Supplemental Nutrition Assistance Program. ISU SNAP-Ed direct nutrition education aims to equip Iowans with low-income with the knowledge and skills to make healthy food choices and save money on food expenses. ISU SNAP-Ed PSE aims to make the healthiest choice the easiest choice in the food pantry environment. Prior to Federal …
Characterization Of The Disease-Causing Mechanism Of Kif3b Mutations From Ciliopathy Patients, Jessica M. Adams, Caleb Sawe, Skye Rogers, Jordyn Reid, Ronith Dasari, Martin F. Engelke
Characterization Of The Disease-Causing Mechanism Of Kif3b Mutations From Ciliopathy Patients, Jessica M. Adams, Caleb Sawe, Skye Rogers, Jordyn Reid, Ronith Dasari, Martin F. Engelke
Faculty Publications – Biological Sciences
The heterodimeric kinesin-2 motor (KIF3A/KIF3B with accessory protein KAP3) drives intraflagellar transport, essential for ciliogenesis and ciliary function. Three point mutations in the KIF3B subunit have recently been linked to disease in humans (E250Q and L523P) and Bengal cats (A334T) (Cogné et al., Am. J. Hum. Genet., 2020, 106, 893–904). Patients display retinal atrophy and, in some cases, other ciliopathy phenotypes. However, the molecular mechanism leading to disease is currently unknown. Here, we used Kif3a−/−;Kif3b−/− (knockout) 3T3 cells, which cannot make cilia, to characterize these mutations. While reexpression of KIF3B(E250Q) and KIF3B(L523P) did not rescue ciliogenesis, reexpression …
Past And Recent Anthropogenic Pressures Drive Rapid Changes In Riverine Fish Communities, Alain Danet, Xingli Giam, Julian D. Olden, Lise Comte
Past And Recent Anthropogenic Pressures Drive Rapid Changes In Riverine Fish Communities, Alain Danet, Xingli Giam, Julian D. Olden, Lise Comte
Faculty Publications – Biological Sciences
Understanding how and why local communities change is a pressing task for conservation, especially in freshwater systems. It remains challenging because of the complexity of biodiversity changes, driven by the spatio-temporal heterogeneity of human pressures. Using a compilation of riverine fish community time series (93% between 1993 and 2019) across the Palaearctic, Nearctic and Australasia realms, we assessed how past and recent anthropogenic pressures drive community changes across both space and time. We found evidence of rapid changes in community composition of 30% per decade characterized by important changes in the dominant species, together with a 13% increase in total …
Examining Differences In Self-Concept And Language Between Monolingual And Bilingual Undergraduate Students, Marilyn Vega-Wagner
Examining Differences In Self-Concept And Language Between Monolingual And Bilingual Undergraduate Students, Marilyn Vega-Wagner
University of the Pacific Theses and Dissertations
The literature is lacking in studies that examine self-concept and language status among individuals older than adolescence. The purpose of this study is to conduct a quantitative nonexperimental comparative design to examine differences in self-concept and language status (monolingual or bilingual) between male and female undergraduate students in California. A total of 97 participants were examined in the study. The researcher conducted descriptive statistics on the demographics as well as a MANOVA and an ANOVA to answer the proposed research question. Based on the findings presented, the researcher failed to reject the null hypothesis of research question 1: There is …
Engagement Between African American Male Students And The Community College, Parrish Geary
Engagement Between African American Male Students And The Community College, Parrish Geary
University of the Pacific Theses and Dissertations
Using data from the Community College Survey of Men designed by the Community College Equity Assessment Lab—Minority Male Community College Collaborative at San Diego State University, this study examined factors influencing in- and out-of-classroom engagement of African American male students at community colleges in California. The results suggested positive relationships between multiple predictors and independent variables on ethos factors for African American men. Additionally, the outcomes showed that 4 of the 5 independent variables were significant for African American men (i.e., personal relationships, faculty acknowledgment, belonging, and feeling welcomed). A review of the standardized beta coefficients revealed that the strongest …
The Decline Of Science In The Early Years: A Diagnosis And A Plan Of Action, Jennifer Bentley
The Decline Of Science In The Early Years: A Diagnosis And A Plan Of Action, Jennifer Bentley
University of the Pacific Theses and Dissertations
Science instruction in the early years of a student’s education career is essential to a student successfully continuing science in their secondary and postsecondary careers. However, the amount of high-quality science instruction students receive at the elementary level has been steadily declining for two decades, resulting in an inequitable imbalance in those who pursue STEM careers, a lack of critical science literacy in the U.S. populace, and a shortage of qualified employees entering the U.S. economy. Much of the lack of science instruction can be traced to decreased training of teachers to teach science during elementary credentialing programs or the …
Transforming Land And Home Ownership: Emergent Strategy And Community Cultural Wealth In Developing Community Land Trusts, Ahmed Naguib
Transforming Land And Home Ownership: Emergent Strategy And Community Cultural Wealth In Developing Community Land Trusts, Ahmed Naguib
University of the Pacific Theses and Dissertations
This dissertation investigates the transformative potential of Community Land Trusts (CLTs) in reimagining land and homeownership within the context of capitalist real estate markets. Utilizing a qualitative research framework that combines narrative inquiry with Emergent Strategy and Community Cultural Wealth theories, this study explores the intricacies of developing CLTs as a counter-narrative to traditional models of property ownership. Through extensive narrative analysis of four distinct CLTs in California, this research highlights the complex challenges and innovative strategies employed to scale CLTs in competitive urban markets. The findings reveal how CLTs leverage emergent strategy and community cultural wealth to navigate and …
From Elementary School To Doctoral Education: An Autoethnographic Journey, Gwendolyn D. Dailey
From Elementary School To Doctoral Education: An Autoethnographic Journey, Gwendolyn D. Dailey
University of the Pacific Theses and Dissertations
Every child has a right to education, and their skin color should not determine their education quality. However, since the landmark case of Brown v. Board of Education (1954), it has been proven that race continues to matter in the success and failure of education (Delgado & Stefancic, 2001). The persistent achievement gaps between students of different racial and ethnic backgrounds, as well as the disparities in access to high-quality educational opportunities, demonstrate how race and ethnicity shape the educational experiences of students of color (Stanford Center for Education Policy Analysis, 2012). Unfortunately, stories such as Ruby Bridges of New …
On The Influence Of Private Stimulus Magnitude When Reporting Private Events, Christian T. Hickman
On The Influence Of Private Stimulus Magnitude When Reporting Private Events, Christian T. Hickman
University of the Pacific Theses and Dissertations
The nature of private events provides challenges to developing a scientific understanding of the conditions under which humans learn to describe private events. Replicating and extending procedures from Stocco et al. (2014), we further evaluated the conditions under which verbal responses come under the control of private stimuli. Given that some participants vocal responses came under the control of public stimuli in Stocco et al. (2014), we implemented more subtle public accompaniments with all participants to reduce the likelihood of public stimuli acquiring control of participant’s verbal responses. Further, we systematically manipulated the visual clarity of the presented stimuli using …
The Role Of The Unfolded Protein Response In Fatty Liver Disease, Anusha L. Murshed
The Role Of The Unfolded Protein Response In Fatty Liver Disease, Anusha L. Murshed
University of the Pacific Theses and Dissertations
The unfolded protein response (UPR) is composed of three highly conserved pathways (ATF6, IRE1, PERK). Cellular stressors induce protein misfolding and aggregation in the endoplasmic reticulum (ER). This signaling pathway maintains protein homeostasis when there is stress in the ER. When the UPR is activated, the eukaryotic initiation factor 2 alpha (eIF2α) becomes phosphorylated, which inhibits global mRNA translation. If ER stress remains chronically unmitigated, the UPR induces apoptosis. GADD34 and CReP shift in expression when the UPR is activated and work as phosphatases and dephosphorylate eIF2α in a feedback loop, allowing protein synthesis to resume. Several human diseases, including …