Digital Commons Network^™

Transforming Growth Factor-Beta Is Increased In Sputum From Individuals With Rheumatoid Arthritis-Associated Pulmonary Fibrosis, Timothy M. Wilson, Matthew Bolt, Andrew Stahly, Joyce S. Lee, Tami J. Bang, Peter B. Sachs, Kevin D. Deane, Stephen M. Humphries, Joshua J. Solomon, M. Kristen Demoruelle

Division of Rheumatology Faculty Papers

BACKGROUND: Interstitial lung disease (ILD) develops in 5-10% of patients with RA and contributes significantly to morbidity and mortality, particularly in those with a fibrotic phenotype. Yet, biomarkers to reliably identify RA patients with underlying pulmonary fibrosis are inadequate. Herein, we used sputum to identify lung-based biomarkers that distinguish RA patients with underlying pulmonary fibrosis and may better inform underlying pathogenesis in RA-ILD.

METHODS: We included 37 RA patients with pulmonary fibrosis (RA-PF) and 30 RA patients without ILD (RA-no-ILD). Induced sputum and serum were tested for TGF-β levels by immunoassay. DNA was extracted to determine presence of the MUC5B …

Multi-Omic Analysis Of Phototrophic Extracellular Electron Uptake In Novel Rhodovulum Spp. Isolated From A Marine Estuary, Emily J. Davenport

Arts & Sciences Graduate Student Theses and Dissertations

Microbial metabolisms are incredibly versatile and dynamic, allowing adaptive strategies for growth in even the most limiting environments. For an ever-increasing number of microbes, this includes utilizing soluble or insoluble inorganic mineral species as electron donors, driving geochemical cycles and microbial metabolisms. This metabolic function of transporting electrons derived from the extracellular environment across cell membranes is called extracellular electron uptake (EEU). Within (photo)autotrophs, (p)EEU also sustains CO2 fixation to cell biomass, implicating a potentially fundamental role of microbial carbon cycling in aquatic and soil ecosystems. A model metabolic scheme of pEEU occurring in natural environments is photoferrotrophy, which pairs …

Critical Review Of Loneliness Rates Among Undergraduates, Emily Schmitz

Psychology Student Publications

This study assesses loneliness rates among undergraduates from fall 2008 to spring 2019 through a secondary analysis of the National College Health Assessment II (NCHA II). The NCHA II, a comprehensive and nationally representative survey, covers a wide range of mental and physical health issues among U.S. college students. The survey consisted of questions which had students self-identify if they have felt very lonely within the last 2 weeks, 30 days, and 12 months. The study revealed that 54.90% to 67.40% of undergraduate students reported feeling very lonely during these survey periods. The results showed that most undergraduates experienced loneliness, …

Mild Traumatic Brain Injuries In Justice-Involved Individuals And Executive Function Consequences On Transition And Reentry Into The Community ​, Alaina L. Randerson, Michael Sutcliffe, Cassandra Nelson, Ariana Gonzalez

Fall 2024 OTD Capstone Symposium

The United States has the highest documented incarceration rate in the world (Carson, 2022), with an increasing number of justice-involved individuals (JII) potentially affected by mild traumatic brain injury (mTBI). Despite the high prevalence of mTBIs in the general population, limited research exists on the prevalence and impact of mTBIs in JII. Preliminary evidence suggests that the prevalence of mTBIs in incarcerated individuals is 50 times higher than in the general public (Siegler et al., 2017). This study aimed to explore the lived experiences of JII with mTBI, focusing on the origin of mTBIs, executive dysfunction, and the occupational barriers …

Older Adult's Fall Prevention Program, Myles Butler, Rebecca King

Fall 2024 OTD Capstone Symposium

The decline in bodily functions with aging increases older adults' vulnerability to falls, which is a leading cause of death within this population. The poster presents an educational based fall prevention program focused on safety awareness and risk management for older adults. In conclusion, implementing a fall prevention program leads to increased awareness regarding risk factors that are detrimental to the safety and well-being of the older adult community

Occupational Therapy Role In Aiding Health Management For Caregivers Of Children With Neurological Conditions, Peyton Mcgee, Mary Jan Greer, Caitlin Boyd

Fall 2024 OTD Capstone Symposium

Neurological disorders are identified as a dysfunction on any part of the nervous system that cause disability (Kumar et al., 2022). In order to enhance the outcome of children with neurological conditions, there should be an emphasis on the role and well-being of their caregivers. Common symptoms of neurological disorders among children include delayed developmental milestones, seizures and epilepsy, regression of skills, abnormal movements and behaviors, headaches, sensory processing issues, and communication difficulties. Adjusting to a new normal can be overwhelming for caregivers, especially when children transition out of rehab. The aim of the proposed capstone project is to aid …

Evaluations Of Digital Public Health Interventions In The Who Southeast Asia Region: A Systematic Literature Review, Nachiket Gudi, Elstin Anbu Raj, Beate Jahn, Uwe Siebert

Open Access archive

Introduction Digital health technologies have been enhancing the capacity of healthcare providers and, thereby, the delivery of targeted health services. The Southeast Asia Region (SEAR) has invested in strengthening digital public health. Many digital health interventions have been implemented in public health settings but are rarely assessed using the holistic health technology assessment (HTA) approach. Methods A systematic literature review was performed to provide an overview of evaluations of digital public health interventions in the World Health Organization (WHO) SEAR. Searches were conducted on four electronic databases. Screening title abstracts and full texts was independently conducted by two reviewers, followed …

Oculomotor Nerve Palsy Recovery Following Microsurgery Vs. Endovascular Treatment Of Posterior Communicating Artery Aneurysms: A Comparative Meta-Analysis Of Short- And Long-Term Outcomes, Rahim Abo Kasem, Conor Cunningham, Sameh Samir Elawady, Mohammad Mahdi Sowlat, Sofia Babool, Saad Hulou, Zachary Hubbard, Atakan Orscelik, Basel Musmar, Alejandro Spiotta

Department of Neurosurgery Faculty Papers

Recent advancements in endovascular treatment (EVT) and different views on optimal management for posterior communicating artery (PComA) aneurysms with oculomotor nerve palsy (ONP) highlight a need to compare recovery timelines between microsurgery and EVT; heterogeneous outcomes and influencing factors may also affect results. A comprehensive systematic review and meta-analysis were conducted by searching PubMed, Embase, Scopus, and Web of Science databases. The extracted data encompassed patient demographics, details on treatment modalities and timing, and characteristics of PComA aneurysms ONP caused by either unruptured or ruptured aneurysms. The primary outcome was ONP favorable recovery, defined as the resolution of admission symptoms, …

Rental Property Demand And Supply Analysis Using Machine Learning, Ahmed Amiri

Theses

The real estate market in Dubai is famous for its activity and stimulating potential due to the geographical position of the emirate, well-developed transport and legal framework. Timely determination and prediction of rental price is crucial for investors, property owners and managers, tenants and authorities in their decision making to maximize returns and ensure market stability. Traditional approaches are insufficient for the analysis of the temporal and spatial relations between property characteristics and market processes, which require the use of sophisticated machine learning algorithms. This paper aims to predict the rental prices of properties in Dubai using machine learning models …

Social Media Intelligence: Responding To Crime And Violence In The Digital World, Chloe Lynn Sitton

Theses

The integration of social media into everyday life has transformed how crime is committed, communicated, and investigated. This capstone project examines the emerging field of social media intelligence and its growing influence on modern policing, surveillance, and the community. Drawing from sociological theory, law enforcement practice, legal analysis, and community-based research, this project offers a far-reaching interdisciplinary view of how social media is shaping crime and justice in the United States.

Editor’S Introduction, Michael D. Pante

Philippine Studies: Historical and Ethnographic Viewpoints

No abstract provided.

Leadership Strategies Indigenous Canadian Entrepreneurs Use To Sustain Their Business, Sherry Tyeesum Mattice

Walden Dissertations and Doctoral Studies

Indigenous Canadian small business entrepreneurs face a high risk of failure within five years of operation. These entrepreneurs encounter challenges such as limited access to capital and skilled employees and must develop strategies to sustain and grow their businesses. Grounded in the theory of constraints, the purpose of this qualitative multiple-case study was to explore strategies employed by Indigenous small business entrepreneurs to effectively sustain their businesses beyond 5 years. The participants were six Indigenous small business entrepreneurs in British Columbia who implemented strategies to sustain their businesses beyond 5 years. Data were collected through semistructured interviews and by reviewing …

Connections Between Household Socioeconomic Status, Modifiable Risk Factors, And Diabetes Status Among Adults In Jamaica, Sheriann Elizabeth Reid

Walden Dissertations and Doctoral Studies

Globally, diabetes is one of the most prevalent and challenging disorders. In Jamaica, the prevalence of the disease has increased by 42% since 2001. This study explored the connection between household socioeconomic status, modifiable risk factors, and diabetes status among adults in Jamaica using the social-ecological model. The study explored whether household socioeconomic status and modifiable risk factors were associated with diabetes and whether they predicted diabetes among Jamaican adults. A quantitative cross-sectional design was used to analyze data with 11,206 respondents from the Jamaica Survey of Living Conditions 2019 dataset. Binary logistic regression analysis revealed statistically significant associations between …

Strategies Small Business Leaders Use To Retain Employees To Reduce Turnover Costs, Karla Gilchrist-Saunders

Walden Dissertations and Doctoral Studies

Failure to retain employees negatively affects organizational financial sustainability. Small business leaders become concerned when their organizations fail to retain employees, resulting in increased costs and decreased competitiveness, organizational knowledge, team dynamics, and valuable human resources. Grounded in transformational leadership theory, the purpose of this qualitative pragmatic inquiry study was to identify and explore leadership strategies some small business leaders use to retain employees to reduce turnover costs. The participants were six small business leaders in the Washington, DC, metropolitan area with successful strategies used to retain employees to reduce turnover costs. Data were collected from semistructured interviews and publicly …

Briar Hill Realty Llc V. Reisner

All Decisions

In this nonpayment proceeding, the landlord obtained a default judgment against the tenant. The tenant moved to vacate the default judgment, arguing that the landlord's agent misled him into believing he did not need to respond to the court proceedings. The court granted the tenant's motion, finding that the landlord's agent's actions constituted extrinsic fraud, which warranted vacating the judgment even without a showing of a meritorious defense. The court emphasized the importance of preserving the integrity of the legal process and preventing situations where parties are misled into believing they do not need to defend themselves in court.

Racial Disparities In Cesarean Section Rates Between Non-Hispanic Black And Non-Hispanic White Populations In The United States, Yanchao Yang, Margaret Mullen, Guangda Zhang

Business Analytics Faculty Publications

This study uses national natality data from the National Vital Statistics System, provided by the National Center for Health Statistics, covering the years 2011 to 2018 (N = 23,810,031) to investigate racial disparities in cesarean section (C-section) rates between non-Hispanic Black and non-Hispanic White mothers in the United States. This analysis offers a comprehensive perspective on the factors contributing to C-section disparities by considering mothers' demographic characteristics, health conditions, and infant health status. Using multivariable logistic regression, the findings reveal consistently higher C-section rates for non-Hispanic Black mothers compared to non-Hispanic White mothers, with the gap widening over time. …

Using Bivalves As An Indicator For Fecal Bacteria, Kamala Chuss

Honors Scholar Theses

This project focuses on the integration of fecal bacteria from warm-blooded animals into bivalve tissue, and the utilization of bivalves as an indicator for fecal bacteria in waterways. Bivalves may give a more representative long-term average of fecal bacteria in water as compared to direct water testing. The primary objective is to create a standard operating procedure to use bacterial testing of bivalves as a proxy for bacteria concentration in the water. This method can be used in places where bivalves do not already exist by adding them to a body of water, or by collecting bivalves that already exist …

Grain Boundary Solute Segregation Across The 5d Space Of Crystallographic Character, Lydia Harris Serafin

Theses and Dissertations

Solute segregation in materials with grain boundaries (GBs) has emerged as a popular method to thermodynamically stabilize nanocrystalline structures. However, the impact of varied GB crystallographic character on solute segregation has never been thoroughly examined. This work examines Co solute segregation in a dataset of 7272 Al bicrystal GBs that span the 5D space of GB crystallographic character. Considerable attention is paid to verification of the calculations in the diverse and large set of GBs. In addition, the results of this work are favorably validated against similar bicrystal and polycrystal simulations. As with other work, we show that Co atoms …

Social Status, Economic Development And Female Labor Force (Non) Participation, Kaivan Munshi, Swapnil Singh

Cowles Foundation Discussion Papers

This research provides a status-based explanation for the high rates of female labor force nonparticipation (FLFNP) and the sustained increase in these rates over time that have been documented in many developing economies. This explanation is based on the idea that households or ethnic groups can signal their wealth, and thereby increase their social status, by withdrawing women from the labor force. If the value of social status or the willingness to bear the signaling cost is increasing with economic development, then this would explain the persistent increase in FLFNP. To provide empirical support for this argument, we utilize two …

Detection And Monitoring Of Stress Using Wearables: A Systematic Review, Anuja Pinge, Vinaya Gad, Dheryta Jaisinghani, Surjya Ghosh, Sougata Sen

Faculty Publications

Over the last few years, wearable devices have witnessed immense changes in terms of sensing capabilities. Wearable devices, with their ever-increasing number of sensors, have been instrumental in monitoring human activities, health-related indicators, and overall wellness. One health-related area that has rapidly adopted wearable devices is the mental health monitoring and well-being area, which covers problems such as psychological distress. The continuous monitoring capability of wearable devices allows the detection and monitoring of stress, thus enabling early detection of mental health problems. In this paper, we present a systematic review of the different types of sensors and wearable devices used …

Feasibility Of Large Language Models For Ceus Li-Rads Categorization Of Small Liver Nodules In Patients At Risk For Hepatocellular Carcinoma, Jiayan Huang, Rui Yang, Xiaotong Huang, Keyu Zeng, Yan Liu, Jun Luo, Andrej Lyshchik, Qiang Lu

Department of Radiology Faculty Papers

BACKGROUND: Large language models (LLMs) offer opportunities to enhance radiological applications, but their performance in handling complex tasks remains insufficiently investigated.

PURPOSE: To evaluate the performance of LLMs integrated with Contrast-enhanced Ultrasound Liver Imaging Reporting and Data System (CEUS LI-RADS) in diagnosing small (≤20mm) hepatocellular carcinoma (sHCC) in high-risk patients.

MATERIALS AND METHODS: From November 2014 to December 2023, high-risk HCC patients with untreated small (≤20mm) focal liver lesions (sFLLs), were included in this retrospective study. ChatGPT-4.0, ChatGPT-4o, ChatGPT-4o mini, and Google Gemini were integrated with imaging features from structured CEUS LI-RADS reports to assess their diagnostic performance for sHCC. …

Achieving Inter- And Transdisciplinarity In Ecohealth: Insights From A Rodent-Borne Disease Project In A Polycrisis Era, Isabelle Arpin, Clémence Massart, Vincent Bourret, Guillaume Castel, Valeria Carolina Colombo, Jana Eccard, Jasmin Firozpoor, Maciej Grzybek, Heikki A. Henttonen, Herwig Leirs, Andrew Mcmanus, Ben Roche, Tarja Sironen, Vincent Sluydts, Peter Stuart, Annetta Zintl, Nathalie Charbonnel

Publications

Introduction: Inter- and transdisciplinary research (ITDR) is increasingly promoted to address “wicked problems”, particularly in health sectors adopting approaches like Ecohealth. Our Ecohealth-inspired project on rodent-borne diseases, initiated just before the COVID-19 pandemic, provided an opportunity to evaluate ITDR implementation.

Methods: We employed a recently developed semi-quantitative evaluation method to measure our project’s success in achieving ITDR and analyzed factors influencing this achievement.

Results: The project showed strengths in system description, team task allocation, and data sharing, but had lower scores in engaging societal actors throughout the project cycle.

Discussion: We identified the underexplored influence of problem wickedness as a …

Reversing Chronic Disease Through Functional Medicine: Acknowledging Privilege And Seeking Justice, Rosalynn A. Vega

Anthropology Faculty Publications

This piece is based on twenty-eight months of digital-auto-ethnographic research. While my research methods included traditional ethnographic research in face-to-face settings and digital ethnography, my personal experience is also embedded in the work. In this piece, you will find “interludes” that provide glimpses into my healing journey. When writing in this autoethnographic register, I provide “thick descriptions” (Geertz 3) of how I experienced illness and recovery. By including my own story, I am acknowledging that the observed and the observer are inextricably intertwined. All ethnography is relational. Ethnographic data results from a trusting relationship between ethnographer and participant. Furthermore, in …

Unraveling The Relationship Between Sleep Behaviors And Physical Activity In The United States: Insights From 2015 To 2020 Nhanes Data, Deepali K Ernest, Bipin Singh, Fathimath Shamna, Elizabeth A Onugha, Shreela V Sharma

Faculty, Staff and Student Publications

Background: Physical activity is an important component of metabolic health. However, little is known about the impact of specific types/intensities of physical activity on sleep health, especially among ethnically diverse populations. We examined the association of various sleep behaviors with moderate to vigorous work/recreational activity.

Methods: Self-reported data from the National Health and Nutrition Examination Survey 2015-2020 were cross-sectionally analyzed for a sample of 11,039 participants in the United States (U.S.). Weighted univariate logistic regressions determined unadjusted associations, while weighted multivariable regression models adjusting for age, sex, ethnicity, BMI categories, and socio-economic status assessed the multivariable associations with moderate and …

Examining The Internet Hunting Styles Of Violent Sexual Predators Who Rape And Murder Their Victims, Rebecca Meyers

Walden Dissertations and Doctoral Studies

The proposed study sought to explore the impact of the internet on the hunting styles of sexual predators who sexually assault and kill their victims. A sample of 32 cases, divided equally among offenders who used the internet to target adult females and those who did not use the internet, was used for the study. The findings showed that various internet-based platforms were used for targeting, including dating apps such as Grindr, Match.com, Meetme.com, Tinder, Craigslist, Sex chat rooms, Kik Messenger, and BDSM sites. Three themes emerged about the impact of the internet on the hunting styles of sexual predators …

Exploring Kindergarten Teachers' Perspectives On The Interpretation Of Standards In A Developmentally Appropriate Way In Kindergarten Classrooms, Shawanza Demetrist Lockett

Walden Dissertations and Doctoral Studies

Many kindergarten teachers are feeling the effects of standard-based education. The problem is that it is unknown whether teachers implement mandated state standards in a developmentally appropriate way. The purpose of this basic qualitative study was to investigate kindergarten teachers’ perspectives on implementing standards in a developmentally appropriate manner. Shulman’s theory of teacher knowledge was the conceptual framework for the study. The research question focused on kindergarten teachers’ perspectives of implementing standards in a developmentally appropriate way. Twelve kindergarten teachers were recruited from three Title 1 elementary schools in a rural southeastern state in the United States. Thematic data analysis …

Autoethnographic Examination Of Moral Distress While Working For The For-Profit Substance Use Disorder Treatment Sector, Kapil Nayar

Walden Dissertations and Doctoral Studies

Interpersonal conflicts and moral distress due to authority figures' unethical and illegal practices are widely discussed topics in the literature. Coping with these experiences and becoming a whistleblower, however are understudied in the counseling field, and are often stigmatized yet advocated for in our codes of ethics. The purpose of this qualitative autoethnographic study is to (1) show moral distress exists in the for-profit sector of substance use disorder treatment; (2) moral distress results from counselors discovering evidence of unethical and illegal activities; (3) moral distress results from the act of blowing the whistle and (4) offers a roadmap for …

Reducing Attrition In Medication-Assisted Treatment: Strategies From Behavioral Health Leaders, Tony Shaw

Walden Dissertations and Doctoral Studies

This qualitative case study explores strategies to reduce attrition rates in medication-assisted treatment programs, drawing on the perspectives of behavioral health leaders and guided by the principles of the Baldridge Excellent Framework. It aims to implement effective strategies to enhance client retention and improve treatment outcomes. Drawing from 18 years of professional experience in behavioral health, this research analyzes current practices and identifies interventions to improve program effectiveness. Data collection includes case studies, surveys, and interviews with behavioral health leaders, providing a comprehensive view of the challenges and opportunities within these programs. The study revealed several key factors affecting retention …

Strategies Small Business Leaders Use To Retain Employees To Reduce Turnover Costs, Karla Gilchrist-Saunders

Walden Dissertations and Doctoral Studies

Failure to retain employees negatively affects organizational financial sustainability. Small business leaders become concerned when their organizations fail to retain employees, resulting in increased costs and decreased competitiveness, organizational knowledge, team dynamics, and valuable human resources. Grounded in transformational leadership theory, the purpose of this qualitative pragmatic inquiry study was to identify and explore leadership strategies some small business leaders use to retain employees to reduce turnover costs. The participants were six small business leaders in the Washington, DC, metropolitan area with successful strategies used to retain employees to reduce turnover costs. Data were collected from semistructured interviews and publicly …

The Psychological And Physical Impact Of The Opioid Crisis On Families, Adrienne Antoinette Hunter Wells Green

Walden Dissertations and Doctoral Studies

Many rural areas in the United States have experienced an opioid crisis. Social support programs could be created to address social support for the families affected by opioid addiction. The purpose of this non-experimental, cross-sectional research study was to examine the possible relationship between (a) prescription or non-prescription addiction; (b) opioid addiction or another addiction; (c) the amount of family social support of a family member who has ongoing interactions with the individual struggling with addiction; and (d) stress of the family member in a rural area. Bowen’s family systems theory provided the theoretical framework for the study. A non-probability …