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2024

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Exploring Colorism In Children’S Literature: Sulwe And Black Is Brown Is Tan, Jasmine April Fortunato Jan 2024

Exploring Colorism In Children’S Literature: Sulwe And Black Is Brown Is Tan, Jasmine April Fortunato

Cal Poly Humboldt theses and projects

My analysis of the texts Sulwe by Lupita Nyong'o and Black Is Brown Is Tan by Arnold Adoff works to evaluate the representation of colorism in children’s literature to understand how it is represented and has evolved in its messaging towards a young audience. Using the frameworks of Critical Race Theory, Critical Skin Theory and Color Blindness under a lens of colorism, my research utilizes visual analysis to view how it is physically conveyed and research in the literacy of children in understanding intersectional issues. Utilizing literary analysis, I analyze the ways colorism is discussed and combatted through comparisons, representation, …


Disney Adult Or Disney Cult?: Observing The Effects And Perceptions Of Transmedia Storytelling Onto Fandom, Sara Spradley Jan 2024

Disney Adult Or Disney Cult?: Observing The Effects And Perceptions Of Transmedia Storytelling Onto Fandom, Sara Spradley

Cal Poly Humboldt theses and projects

Transmedia storytelling is the vehicle for narratives to become immersive to their audience through different modalities. The Walt Disney Company employs this form of storytelling by placing any one of its films in the context of attractions and live-action performances, or vice-versa, creating a convergent culture that will follow these products through every medium. This project views transmedia storytelling used by the Walt Disney Company as the reasoning for the Disney Adults' fandom interest in interacting with Disney products. Through the use of discourse analysis, and digital ethnography I will observe this relationship between the use of transmedia storytelling, fandom …


Common Raven Resource Selection, Diet, And Behavior Around A Threatened Shorebird, Janelle Chojnacki Jan 2024

Common Raven Resource Selection, Diet, And Behavior Around A Threatened Shorebird, Janelle Chojnacki

Cal Poly Humboldt theses and projects

Human food subsidies have allowed populations of the common raven (Corvus corax) to expand and increase in density, especially in the western United States, which has amplified predation risk for other native species. Common ravens are well-documented nest predators of the federally threatened Western snowy plover (Anarhynchus nivosus nivosus) in Humboldt County, California; however, little is known about raven movement and foraging behavior in and around snowy plover habitat. Using GPS tracking and behavioral surveys, I examined movement and foraging behavior of beach-going ravens across snowy plover nesting habitat and I explored raven diet through stable isotope …


The Persistent Voice Of The Colonizer: Troubling A Mascot’S Settler-Colonial Past, Linda J. Kuckuk Jan 2024

The Persistent Voice Of The Colonizer: Troubling A Mascot’S Settler-Colonial Past, Linda J. Kuckuk

Cal Poly Humboldt theses and projects

The legacy of settler-colonialism permeates American culture. Remnants of westward expansion remain in our societal divides, political differences, environmental inequities and economic inequalities. Conversations about decolonization, gentrification, and other ongoing practices that precipitate and uphold colonialism are notably found in literature, art, social structures, icons and symbols. Mascots that rely on stereotypes or caricatures can contribute to negative perceptions and reinforce discriminatory attitudes, making it necessary to reevaluate and change representational practices. In this analysis I apply historical, textual, and visual methods to explore Cal Poly Humboldt’s mascot Lucky Logger and identify how this character is a “persistent voice” by …


A Post-Colonial Criticism Of Ernest Callenbach's Ecotopia, Kaitlyn R. O'Dell Jan 2024

A Post-Colonial Criticism Of Ernest Callenbach's Ecotopia, Kaitlyn R. O'Dell

Cal Poly Humboldt theses and projects

The representation of Indigenous land-based cosmologies within Ernest Callenbach’s Ecotopia communicates a real perception of our world through the constructed imaginative society within this speculative fiction novel. Ecotopia is an alternative Pacific West Coast society that counters the dominant United States model in its holistic and green approach. This green society relies heavily on Indigenous ideology but lacks actual Indigenous voices or communities within this white idealized society. This research provides an example of the deconstruction of this popular novel to its main problematic components, establishing why the use of Indigenous beliefs and values can cause negative implications to the …


The Impact Of A Structured Exercise Program On The Pre-Established Exercise Goals For Individuals With Disabilities, Emily C. Batini Jan 2024

The Impact Of A Structured Exercise Program On The Pre-Established Exercise Goals For Individuals With Disabilities, Emily C. Batini

Cal Poly Humboldt theses and projects

This study aimed to identify the efficacy of a structured exercise program emphasizing family involvement and self-determination theory in meeting pre-established fitness goals for adults with disabilities. To measure physical strength and endurance changes, the 6-minute walk test, the curl-up, and push-up tests were utilized. A single-subject changing-criterion design was used in this study over the course of six weeks. Results indicated a positive relationship between the intervention and increased physical strength and endurance, according to testing results. Few participants met the criterion for each phase. However, many did demonstrate an increase in the distance walked, push-ups, and curl-ups completed …


Beyond Exhausted: An Investigation Into Teacher Burnout And Teacher Attrition, Michael Carino Morales Sr. Jan 2024

Beyond Exhausted: An Investigation Into Teacher Burnout And Teacher Attrition, Michael Carino Morales Sr.

Cal Poly Humboldt theses and projects

The role of a teacher is an important one. Teachers serve as educators, mentors, and guides for their students. Teachers often invest their time, energy, and emotions into their work. They do essential work and frequently receive little in return.

This thesis examines the many challenges that teachers face today. It focuses on teacher workload, financial pressures, curriculum debates, and the effects of the COVID-19 global pandemic.

The thesis is divided into three sections. It begins with my experiences as a public school teacher and my difficulties, such as heavy workloads and curriculum management. That is followed by the literature …


Characterizing The Beneficial Uses Of The Arcata Marsh Constructed Wetland Treatment System And Wildlife Sanctuary, Andrew S. Wolff Jan 2024

Characterizing The Beneficial Uses Of The Arcata Marsh Constructed Wetland Treatment System And Wildlife Sanctuary, Andrew S. Wolff

Cal Poly Humboldt theses and projects

The Arcata Marsh Constructed Wetland Treatment System and Wildlife Sanctuary, located in Arcata California, has been in operation since 1986. Not only has it served as the wastewater treatment facility for the city, it has also provided other beneficial uses such as acting as a sanctuary for bird, mammal, amphibian, and macroinvertebrate species. With facility upgrades currently underway, it has become important to revisit the beneficial uses of the Arcata Marsh. This project aimed to identify and characterize these beneficial uses. Literature review was conducted, and eleven beneficial uses were identified. Existing and newly obtained data were analyzed to characterize …


Simulated Effects Of Postpartum Depression On Maternal-Infant Bonding: Mediated By Reward-Related Responses To Infant Facial Cuteness, Caitlin Harp Jan 2024

Simulated Effects Of Postpartum Depression On Maternal-Infant Bonding: Mediated By Reward-Related Responses To Infant Facial Cuteness, Caitlin Harp

Cal Poly Humboldt theses and projects

Infant cuteness (facial cuteness in particular) is linked to evolutionary adaptations to motivate caretaking and protective behaviors (Kringelbach et al., 2008). Previous neuroimaging work has demonstrated that infant cuteness activates reward-related regions in the brain (Glocker et al., 2009) and behavioral work suggests that the reward value of cuteness is linked to maternal tendencies (Hahn et al., 2015). It is estimated that 15% of new mothers experience postpartum depression (PPD) (Wisner et al., 2013), which impacts the mesolimbic system and is linked to anhedonia (i.e., reduced ability to experience pleasure). Based on the above literature, this study used a simulated …


"Kindness Eases Change / Love Quiets Fear": Mapping Change And Movement In Octavia Butler's Parable Of The Sower, Elizabeth Hershey Jan 2024

"Kindness Eases Change / Love Quiets Fear": Mapping Change And Movement In Octavia Butler's Parable Of The Sower, Elizabeth Hershey

Cal Poly Humboldt theses and projects

In this project I take a digital mapping approach to reading and analyzing Octavia Butler’s Parable of the Sower. A lot has been said about this novel’s relevance to our own world, and the ways it forces us to think about possible futures. To contribute to the conversations surrounding this novel, I add a digital humanities element to the conversation in order to see what digital mapping has to offer in the way of literary analysis and connecting this novel to our own world. Since the novel is so focused on movement and change, I mapped out the movement of …


“Bad At Reading”: Narratives Of Boys With Negative Reading Self-Concept, Aimee Talmadge Jan 2024

“Bad At Reading”: Narratives Of Boys With Negative Reading Self-Concept, Aimee Talmadge

Cal Poly Humboldt theses and projects

There is a clear and consistent gender gap between students who view themselves as readers and those who do not (Love & Hamston, 2003). Overwhelmingly, young men report a lower self-perception of their ability and interest in reading and literacy, and this in turn impacts their growth and motivation in literacy learning. Through this study, I interviewed six students, specifically male high school students who self-identified as bad at reading or disliking reading. Through one-on-one interviews and focus groups, I explored how they viewed themselves as “non-readers” and why their reading self-perception is negative. The findings show how the lack …


The Potential For Competency-Based Teaching Methodologies To Increase Intervention Procedural Fidelity And Reduce Self-Reported Verbal Behavior Associated With Turnover In Behavior Technicians, Dean I. Shearer Jan 2024

The Potential For Competency-Based Teaching Methodologies To Increase Intervention Procedural Fidelity And Reduce Self-Reported Verbal Behavior Associated With Turnover In Behavior Technicians, Dean I. Shearer

Cal Poly Humboldt theses and projects

Within the field of applied behavior analysis, behavior technicians (staff who are supervised by behavioral analysists and provide direct services to clients) experience relatively high rates of turnover. It is possible that improved teaching methodologies which boost the efficacy of these staff may help reduce this turnover by reducing verbal behavior associated with burnout and improve perceptions of training and supervision. We compared intervention procedural fidelity and staff ratings of burnout, supervision, and satisfaction with training following a didactic training, a behavioral skills training, and after a month-long follow up. We found that when mastery criteria were set sufficiently high …


Interactions Between New Zealand Mud Snails (Potamopyrgus Antipodarum) And Toxic Cyanoabacteria (Anabaena) In Baduwa’T (Mad River), Humboldt County, California, Cecilia F. Kennelly Jan 2024

Interactions Between New Zealand Mud Snails (Potamopyrgus Antipodarum) And Toxic Cyanoabacteria (Anabaena) In Baduwa’T (Mad River), Humboldt County, California, Cecilia F. Kennelly

Cal Poly Humboldt theses and projects

Invasive species in freshwater systems are circulated around the globe, wreaking havoc on natural communities. The New Zealand mud snail (Potamopyrgus antipodarum) is a very successful aquatic invader that has established populations in freshwater streams, lakes, and rivers around the globe. The goal of this project was to evaluate the interactions of invasive New Zealand mud snails (NZMS) and toxic cyanobacteria Anabaena in the Mad River in Humboldt County, California. These two species of concern are found in similar habitats along the river, but their whether NZMS consume Anabaena or affect toxin production is unknown. First, I conducted …


Finding Connection: Teaching With Culturally Responsive Texts, Chloe N. Pounds Jan 2024

Finding Connection: Teaching With Culturally Responsive Texts, Chloe N. Pounds

Cal Poly Humboldt theses and projects

Deciding which texts to teach in English Language Arts (ELA) classrooms poses challenges for educators. Traditionally, many teachers rely on established curricula, however, the increasing diversity of student populations highlights the need for texts that reflect student interests and backgrounds, as well as the need for culturally responsive pedagogical practices. To investigate student perceptions and benefits of culturally diverse texts, I created a short story unit and collected student reflections and teacher observations.


Producing Knowledge Together: A Participatory Approach To Synthesising Research Across A Large‑Scale Collaboration In Aboriginal And Torres Strait Islander Health, Kathleen P. Conte, Alison Laycock, Jodie Bailie, Emma Walke, Leigh-Ann Onnis, Lynette Feeney, Erika Langham, Multiple Additional Authors Jan 2024

Producing Knowledge Together: A Participatory Approach To Synthesising Research Across A Large‑Scale Collaboration In Aboriginal And Torres Strait Islander Health, Kathleen P. Conte, Alison Laycock, Jodie Bailie, Emma Walke, Leigh-Ann Onnis, Lynette Feeney, Erika Langham, Multiple Additional Authors

Homelessness Research & Action Collaborative Publications and Presentations

Background

Despite that stakeholder participation in evidence synthesis could result in more useful outcomes, there are few examples of processes that actively involve them in synthesis work. Techniques are needed that engage diverse stakeholders as equal partners in knowledge co-production. The aims of this paper are to describe an innovative participatory process of synthesising a large body of academic research products and compare the findings of the participatory process against two traditional approaches to synthesis: a rapid review and a structured review.

Methods

First, a rapid synthesis of all research outputs (n = 86) was conducted by researchers with …


Alternative Shelter Evaluation Report, Jacen Greene, Todd Ferry, Emily Leickly, Franklin H. Spurbeck Jan 2024

Alternative Shelter Evaluation Report, Jacen Greene, Todd Ferry, Emily Leickly, Franklin H. Spurbeck

Homelessness Research & Action Collaborative Publications and Presentations

This report summarizes research by Portland State University’s Homelessness Research & Action Collaborative for the Joint Office of Homeless Services on the cost, participant experiences, and client outcomes in village-style and motel shelters as compared to each other and to traditional, congregate shelters.


Exploring The Realities Of Queer/Trans, Black, Indigenous, And/Or People Of Color Students At Humboldt State University, Kat Hồng Nguyễn Jan 2024

Exploring The Realities Of Queer/Trans, Black, Indigenous, And/Or People Of Color Students At Humboldt State University, Kat Hồng Nguyễn

Cal Poly Humboldt theses and projects

In this thesis, I use participant interviews with 12 queer student activists at Humboldt State University (now Cal Poly Humboldt) and participant observation from 2019-2021 to provide a qualitative analysis of Queer, Trans, Black, Indigenous, and People of Color (QTBIPOC) student knowledge. While student activism is not a primary site of analysis in this paper, all of the participants of this study identify as student activists which has implications on their overall experience. Participants in this study note the institutional efforts to disrupt institutional memory between student leaders and activists. This study was specifically designed to combat this issue by …


Fire Severity Mediates Marten And Fisher Occurrence: Impacts Of The Dixie Fire On A Carnivore Community, Christopher James Collier Jan 2024

Fire Severity Mediates Marten And Fisher Occurrence: Impacts Of The Dixie Fire On A Carnivore Community, Christopher James Collier

Cal Poly Humboldt theses and projects

The consumption of an astounding one million acres resulted from California’s largest single fire to date, the 2021 Dixie Fire. The social and economic losses associated with the fire were immediately apparent, but the effects on wildlife remained unknown. While previous research has suggested mixed or low severity fire may be beneficial to certain wildlife species, the responses to megafires are poorly understood for many carnivores. To better understand these responses to severe fire, I used a random sampling design stratified by burn severity to survey in and around the Dixie Fire footprint using baited camera stations. This allowed me …


Beyond The Classroom: A Land-Based Approach To Outdoor Education, Jacquelyn R. Matthews Jan 2024

Beyond The Classroom: A Land-Based Approach To Outdoor Education, Jacquelyn R. Matthews

Cal Poly Humboldt theses and projects

This pilot project seeks to nurture space for Indigenous perspectives while equipping early childhood educators with tools for integrating diverse epistemology into outdoor learning practices to foster collaborative educational approaches. To align with this effort of shared knowledge, the project intends to offer a culturally sustaining educational tool that can help disrupt dominant approaches by evaluating alternative teaching strategies that center partnerships with local Indigenous communities to move toward equity-centered education. This can be achieved by modeling a resource guide after the theoretical underpinnings of Etuaptmumk Two-Eyed Seeing, and land-based pedagogy. A major component of this resource guide will include …


Physical And Mental Health Benefits Of An Intergenerational Yoga Intervention On Individuals And Communities, Crystal Rose Mckinney Jan 2024

Physical And Mental Health Benefits Of An Intergenerational Yoga Intervention On Individuals And Communities, Crystal Rose Mckinney

Cal Poly Humboldt theses and projects

Intergenerational health programming has been shown to elicit positive physical, mental, psychological and social health benefits of all participants due to the educational impact and social engagement of synchronized movement and understanding of other generations. Research continues to show the efficacy of yoga in mind - body - spirit - connection health benefits and is accessible to bodies across the lifespan. People of all ages can benefit from an intergenerational yoga program, particularly in a rural location where there are less opportunities for physical activity participation. The purpose of this project is to apply for Humboldt Area Foundation + Wild …


Adoption Of Holistic Education Practices: A Survey Of California K-12 Educator Experiences, Arianne M. Nova Jan 2024

Adoption Of Holistic Education Practices: A Survey Of California K-12 Educator Experiences, Arianne M. Nova

Cal Poly Humboldt theses and projects

In a rapidly evolving educational landscape, the federal government must explicitly consider holistic approaches to education as essential for the well-being and future of students in public schools. Holistic education, which extends beyond traditional academics to nurture the 'whole child,' has garnered substantial support in the literature for its positive impact on academic performance, behavior, and student well-being. This research explores educator perspectives on holistic education in a K-12 California school district. By surveying teachers, counselors, school social workers, and principals within this district, I assess their awareness concerning structural levels, available resources, and implementation capabilities related to holistic education. …


Longevity Of Prescribed Fire Effectiveness In Mixed-Evergreen Forests Of The Klamath Mountains, Kaily M. Fineran Jan 2024

Longevity Of Prescribed Fire Effectiveness In Mixed-Evergreen Forests Of The Klamath Mountains, Kaily M. Fineran

Cal Poly Humboldt theses and projects

Prescribed fire is a common management tool used across the western United States to create wildfire-resilient ecosystems and communities. The Klamath Mountains of northern California, USA has experienced numerous, large wildfires in recent years. This is due in part to a combination of highly flammable fuels, uncharacteristic weather events, and high fuel accumulations as a result of fire exclusion and forest management practices. Within the last decade, local land management organizations and the Karuk Tribe have begun re-introducing prescribed fire in low elevation, mixed evergreen forests. While the long-term effects of fuel treatments are not well-known, these efforts provided a …


Effectiveness Of An Inclusive, Small-Group Adapted Aquatics Program On Increasing Vo2max In Children With Autism Spectrum Disorder, Peggy Manuelita Scarborough Jan 2024

Effectiveness Of An Inclusive, Small-Group Adapted Aquatics Program On Increasing Vo2max In Children With Autism Spectrum Disorder, Peggy Manuelita Scarborough

Cal Poly Humboldt theses and projects

There is a need to examine the effectiveness of interventions, such as swimming, that are aimed at increasing physical health and developing psychomotor skills in an inclusive setting for children with ASD. The purpose of this study was to examine the effectiveness of an inclusive, small-group adapted aquatics program on increasing VO2max in children with ASD. Participants included two 11-year-old children diagnosed with ASD. The study took place over eight weeks and included a six-week Small-Group Adapted Aquatics (SGAA) program. Participants were assessed for VO2max using the 20m PACER test during week one and week eight …


Assessment Of Avian Community Structure And Habitat Connectivity In The Fanno Creek Corridor Bird Surveys, Habitat Assessment, And Management Recommendations, Grace Hall Jan 2024

Assessment Of Avian Community Structure And Habitat Connectivity In The Fanno Creek Corridor Bird Surveys, Habitat Assessment, And Management Recommendations, Grace Hall

Environmental Science and Management Professional Master's Project Reports

Urbanization can significantly impact habitat quality and connectivity for avian communities, decreasing species richness and diversity. However, in highly fragmented habitats, urban parks and riparian zones can provide important habitat corridors for birds that facilitate movement and access to essential resources. On the west side of greater Portland, Oregon, Fanno Creek may serve as a habitat corridor for birds and other local wildlife.

Fanno Creek is a 25-kilometer tributary of the Tualatin River that runs through the cities of Portland, Beaverton, Tigard, and Durham in northwestern Oregon. The land surrounding the creek includes residential, commercial, and industrial properties as well …


A Magnetic Constant Torque Mechanism, Gozde Sivka, Dawei Che, Bert Dechant, Colton Bruce, Jonathan Z. Bird Jan 2024

A Magnetic Constant Torque Mechanism, Gozde Sivka, Dawei Che, Bert Dechant, Colton Bruce, Jonathan Z. Bird

Electrical and Computer Engineering Faculty Publications and Presentations

This paper presents the design of a new type of magnetic constant torque mechanism. The constant torque is shown to be created over a prescribed ±65° stroke length and is shown to be highly uniform. The value of the constant torque is adjustable through the relative axial motion of the rotors. The constant torque is created using a simple magnet arrangement which makes use of the axial transverse-flux path of one rotor's magnetic field relative to the azimuthal field flow of the fixed secondary rotor. It is shown that the use of segmented magnets introduces torque ripple.


A Prdm16-Driven Signal Regulates Body Composition In Testosterone-Treated Hypogonadal Men, Siresha Bathina, Georgia Colleluori, Dennis T Villareal, Lina Aguirre, Rui Chen, Reina Armamento-Villareal Jan 2024

A Prdm16-Driven Signal Regulates Body Composition In Testosterone-Treated Hypogonadal Men, Siresha Bathina, Georgia Colleluori, Dennis T Villareal, Lina Aguirre, Rui Chen, Reina Armamento-Villareal

Faculty, Staff and Students Publications

BACKGROUND: Testosterone (T) therapy increases lean mass and reduces total body and truncal fat mass in hypogonadal men. However, the underlying molecular mechanisms for the reciprocal changes in fat and lean mass in humans are not entirely clear.

METHODS: Secondary analysis of specimens obtained from a single-arm, open-label clinical trial on pharmacogenetics of response to T therapy in men with late-onset hypogonadism, conducted between 2011 and 2016 involving 105 men (40-74 years old), who were given intramuscular T cypionate 200 mg every 2 weeks for 18 months. Subcutaneous fat (SCF), peripheral blood mononuclear cells (PBMC) and serum were obtained from …


A Comprehensive Meta-Analysis Of Tissue Resident Memory T Cells And Their Roles In Shaping Immune Microenvironment And Patient Prognosis In Non-Small Cell Lung Cancer, Aidan Shen, Aliesha Garrett, Cheng-Chi Chao, Dongliang Liu, Chao Cheng, Zhaohui Wang, Chen Qian, Yangzhi Zhu, Junhua Mai, Chongming Jiang Jan 2024

A Comprehensive Meta-Analysis Of Tissue Resident Memory T Cells And Their Roles In Shaping Immune Microenvironment And Patient Prognosis In Non-Small Cell Lung Cancer, Aidan Shen, Aliesha Garrett, Cheng-Chi Chao, Dongliang Liu, Chao Cheng, Zhaohui Wang, Chen Qian, Yangzhi Zhu, Junhua Mai, Chongming Jiang

Faculty, Staff and Students Publications

Tissue-resident memory T cells (TRM) are a specialized subset of long-lived memory T cells that reside in peripheral tissues. However, the impact of TRM-related immunosurveillance on the tumor-immune microenvironment (TIME) and tumor progression across various non-small-cell lung cancer (NSCLC) patient populations is yet to be elucidated. Our comprehensive analysis of multiple independent single-cell and bulk RNA-seq datasets of patient NSCLC samples generated reliable, unique TRM signatures, through which we inferred the abundance of TRM in NSCLC. We discovered that TRM abundance is consistently positively correlated with CD4+ T helper 1 cells, M1 macrophages, and resting dendritic cells in the TIME. …


High Prevalence Of A-Β+ Ketosis-Prone Diabetes In Children With Type 2 Diabetes And Diabetic Ketoacidosis At Diagnosis: Evidence From The Rare And Atypical Diabetes Network (Radiant), Elizabeth Kubota-Mishra, Xiaofan Huang, Charles G Minard, Marcela Astudillo, Ahmad Refaey, Graciela Montes, Stephanie Sisley, Nalini Ram, William E Winter, Rochelle N Naylor, Ashok Balasubramanyam, Maria J Redondo, Mustafa Tosur, Radiant Study Group Jan 2024

High Prevalence Of A-Β+ Ketosis-Prone Diabetes In Children With Type 2 Diabetes And Diabetic Ketoacidosis At Diagnosis: Evidence From The Rare And Atypical Diabetes Network (Radiant), Elizabeth Kubota-Mishra, Xiaofan Huang, Charles G Minard, Marcela Astudillo, Ahmad Refaey, Graciela Montes, Stephanie Sisley, Nalini Ram, William E Winter, Rochelle N Naylor, Ashok Balasubramanyam, Maria J Redondo, Mustafa Tosur, Radiant Study Group

Faculty, Staff and Students Publications

BACKGROUND:A−β+ ketosis-prone diabetes (KPD) in adults is characterized by presentation with diabetic ketoacidosis (DKA), negative islet autoantibodies, and preserved β-cell function in persons with a phenotype of obesity-associated type 2 diabetes (T2D). The prevalence of KPD has not been evaluated in children. We investigated children with DKA at “T2D” onset and determined the prevalence and characteristics of pediatric A−β+ KPD within this cohort.

METHODS: We reviewed the records of 716 children with T2D at a large academic hospital and compared clinical characteristics of those with and without DKA at onset. In the …


Development, Implementation, And Evaluation Of Three Outreach Events To Improve Covid-19 Vaccine Uptake Among Racial And Ethnic Minority Communities In Houston, Texas, 2022, Carmin Munoz-Lavanderos, Abiodun Oluyomi, Omar Rosales, Norvin Hernandez, Nana Mensah-Bonsu, Hoda Badr Jan 2024

Development, Implementation, And Evaluation Of Three Outreach Events To Improve Covid-19 Vaccine Uptake Among Racial And Ethnic Minority Communities In Houston, Texas, 2022, Carmin Munoz-Lavanderos, Abiodun Oluyomi, Omar Rosales, Norvin Hernandez, Nana Mensah-Bonsu, Hoda Badr

Faculty, Staff and Students Publications

OBJECTIVES: Lack of access to timely, accurate, and linguistically appropriate COVID-19 information has complicated the dissemination of evidence-based information and contributed to vaccine hesitancy among racial and ethnic minority groups in the United States. We developed community events that provided outreach, education, and access to COVID-19 vaccination to overcome vaccine hesitancy in these communities.

METHODS: Using spatial analysis techniques, we identified 3 communities with low vaccine uptake in Houston, Texas, in fall 2021; engaged 20 stakeholders from these communities via 4 focus groups to understand barriers to vaccination; and developed and implemented 3 COVID-19 vaccine education and outreach events tailored …


Dna Mismatch Repair Defect And Intratumor Heterogeneous Deficiency Differently Impact Immune Responses In Diffuse Large B-Cell Lymphoma, Zijun Y Xu-Monette, Cancan Luo, Li Yu, Yong Li, Govind Bhagat, Alexandar Tzankov, Carlo Visco, Xiangshan Fan, Karen Dybkaer, Ali Sakhdari, Nicholas T Wang, Alyssa F Yuan, April Chiu, Wayne Tam, Youli Zu, Eric D Hsi, Anamarija M Perry, Wenting Song, Dennis O'Malley, Qingyan Au, Harry Nunns, Heounjeong Go, Michael B Møller, Benjamin M Parsons, Santiago Montes-Moreno, Maurilio Ponzoni, Andrés J M Ferreri, Aliyah R Sohani, Jeremy S Abramson, Bing Xu, Ken H Young Jan 2024

Dna Mismatch Repair Defect And Intratumor Heterogeneous Deficiency Differently Impact Immune Responses In Diffuse Large B-Cell Lymphoma, Zijun Y Xu-Monette, Cancan Luo, Li Yu, Yong Li, Govind Bhagat, Alexandar Tzankov, Carlo Visco, Xiangshan Fan, Karen Dybkaer, Ali Sakhdari, Nicholas T Wang, Alyssa F Yuan, April Chiu, Wayne Tam, Youli Zu, Eric D Hsi, Anamarija M Perry, Wenting Song, Dennis O'Malley, Qingyan Au, Harry Nunns, Heounjeong Go, Michael B Møller, Benjamin M Parsons, Santiago Montes-Moreno, Maurilio Ponzoni, Andrés J M Ferreri, Aliyah R Sohani, Jeremy S Abramson, Bing Xu, Ken H Young

Faculty, Staff and Students Publications

Deficient (d) DNA mismatch repair (MMR) is a biomarker predictive of better response to PD-1 blockade immunotherapy in solid tumors. dMMR can be caused by mutations in MMR genes or by protein inactivation, which can be detected by sequencing and immunohistochemistry, respectively. To investigate the role of dMMR in diffuse large B-cell lymphoma (DLBCL), MMR gene mutations and expression of MSH6, MSH2, MLH1, and PMS2 proteins were evaluated by targeted next-generation sequencing and immunohistochemistry in a large cohort of DLBCL patients treated with standard chemoimmunotherapy, and correlated with the tumor immune microenvironment characteristics quantified by fluorescent multiplex immunohistochemistry and gene-expression …