Digital Commons Network^™

Development Of An Age-Appropriate Household Dysfunction Measure And Its Concurrent Validity With Multiple Outcomes Among Middle School Adolescents In Southeast Texas, Sumaita Choudhury, Timothy J Walker, Emily T Hébert, Christine M Markham, Ross Shegog, Robert C Addy, Melissa F Peskin

Faculty, Staff and Student Publications

Existing adverse childhood experience (ACE) measures include a limited number of household dysfunction (HD) items and the use of adult-oriented language that is not always appropriate for middle schoolers. We developed an age-appropriate 10-item HD measure informed by previously validated ACE measures and tested its concurrent validity with dating violence (DV) perpetration, lifetime substance use, and mental health outcomes among middle schoolers in Southeast Texas. This cross-sectional study used the baseline data from a DV prevention intervention program for sixth graders (N = 126), Me & You Tech. Baseline data were collected from March 2023 to April 2023. To …

Identifying Antimalarials That Disrupt Malaria Parasite Transmission When Fed To The Mosquito, Sarah N. Farrell, Anton Cozijnsen, Vanessa Mollard, Papireddy Kancharla, Rozalia A. Dodean, Jane X. Kelly, Geoffrey I. Mcfadden, Christopher D. Goodman

Chemistry Faculty Publications and Presentations

A decade-long decline in malaria cases has plateaued, primarily due to parasite drug resistance and mosquito resistance to insecticides used in bed nets and indoor residual spraying. Here, we explore the innovative control strategy targeting Plasmodium with antimalarials during the mosquito stages. This strategy has the potential to reduce the risk of resistance emerging because a relatively small population of parasites within the mosquito is subject to selection. After validating mosquito feeding strategies, we screened a range of parasiticidal compounds by feeding them to mosquitoes already infected with mouse malaria (P. berghei). Three antimalarials showed activity against P. berghei in …

The Correlation Between Zinc Intake And Superoxide Dismutase Activity With Cognitive Function In The Elderly, Rima Khuzaimah, Fiastuti Witjaksono, Novi Silvia Hardiany

Sultan Qaboos University Medical Journal

Objectives: This study aimed to analyse the correlation between zinc intake and superoxide dismutase (SOD) with cognitive function in the elderly. Thus, the role of zinc as a structural component of SOD, along with SOD’s contribution to cognitive function, can be established. Methods: This cross-sectional study was conducted at Panti Sosial Tresna Wredha Budi Mulia 1 in Jakarta, Indonesia, from July to September 2024. Elderly men and women were included. Zinc intake was assessed using the Semi-Quantitative Food Frequency Questionnaire, while plasma SOD activity was measured by spectrophotometer. Cognitive function was assessed using the Montreal Cognitive Assessment-Indonesia version. Data …

Concomitant Systemic Autoinflammatory Diseases: Diagnostic And Therapeutic Challenges, Eman Al Masroori, Mahadev J. Mal, Reem Abdwani

Sultan Qaboos University Medical Journal

Neonatal-onset multisystem inflammatory disease (NOMID) and familial Mediterranean fever (FMF) are distinct entities within the expanding spectrum of systemic autoinflammatory diseases (SAIDs). We report a 3-month-old infant who presented with recurrent fever, urticarial rash, and polyarthritis. After excluding other causes, anakinra was initiated based on clinical suspicion of NOMID. Despite treatment optimisation, she continued to experience disease flares. An initial autoinflammatory panel and subsequent whole-exome sequencing revealed heterozygous MEFV (M694V and V726A) gene mutations, which did not explain the clinical picture. Further deep sequencing identified NLRP3 (p.Asp305Glu) somatic mosaicism, confirming NOMID. The coexistence of NOMID and FMF presented significant diagnostic …

A Tale Of Two Tracks, Ishrat Husain Dr.

Faculty Research - Newspaper and Magazine Articles

The recent impressive performance of Pakistan’s armed forces against a formidable adversary, enjoying favorable distribution of conventional forces, a 10-times larger economy, six times in population, a leading global exporter of IT and IT-enabled services, having huge forex reserves of over $600 billion, has made the nation proud. The question that needs to be answered is: How come the performance of our military (1971 being an exception) has been so consistently superior compared to our civilian institutions? Why is the gap between these two parallel tracks — military and civil — widening and why have there been no synergies between …

Assessing Consumer Perceptions And Attitudes Towards Cultured Meat Using X (Twitter) Data: Implications For Decision Support, Guoste Pivoraite, Shaofeng Liu, Saeyeon Roh, Guoqing Zhao

Plymouth Business School

Cultured meat (CM) is considered to have a potential to address environmental, sustainability, ethical concerns, and food security, however, consumer acceptance remains a challenge. This study empirically validatesand extends the Cultured Meat Attitude and Perception Assessment (CAPA) model by analysing public discussions on X (Twitter) to understand consumer perceptions of CM. Using BERTopic for topic modelling and qualitative analysis, the study explored unprompted public narratives, mapping them to CAPA constructs to examine how public opinions align with or challenge existing theoretical concepts. The findings revealed a combination of cultural, political, ethical, and economic narratives shaping consumer behaviour and theirdecision-making processes …

Introduction

The Journal of Contemporary Legal Issues

In November 2023, the Institute for Law and Philosophy at the University of San Diego School of Law convened a Symposium on Andrew Koppelman’s recent book, published in 2022, Burning Down the House: How Libertarian Philosophy Was Corrupted by Delusion and Greed. The argument of Andy Koppelman’s book is that whereas modern American libertarianism began admirably with Friedrich Hayek’s corrective to the Depression-era vogue for central economic planning, libertarianism has since devolved into a toxic blend of anarchism, greed, disdain for the weak, and rationalization for environmental catastrophe.

The papers from the Symposium are published in this issue of …

Will The Real F.A. Hayek Please Stand Up!, Eric Mack

The Journal of Contemporary Legal Issues

In this essay, I will argue that neither of these two presentations of Hayek represent the real Hayek. In Part II of this essay, I criticize Koppelman’s contention that there is little distance, if any, between Hayek’s stance on distributive justice and Rawls’s difference principle. In Part III of this essay, I dispute Koppelman’s claim that Hayek is quite receptive to the development and expansion of the regulatory-administrative state. Each of these stances is rejected by Hayek for the same sorts of reasons that stand behind his rejection of central economic planning. Hayek’s critique of central economic planning, his rejection …

We Didn’T Start The Fire: For And Against Koppelman On The Corruption Of Libertarianism, Roderick T. Long

The Journal of Contemporary Legal Issues

At the philosophic core of libertarianism is a set of market-oriented commitments that are entirely compatible with, and indeed congenial to, traditional leftist concerns with the well-being of the disadvantaged in society. But over the past several decades, the libertarian movement has fallen increasingly under the spell of toxic, callous, right-wing versions of libertarianism that scorn empathy while championing the cause of the economic winners in society at the expense of those who lose out.

That’s one way of stating the central thesis of Andrew Koppelman’s book Burning Down the House. And that thesis, so stated, is one I …

Freedom From Libertarianism, Joseph Fishkin

The Journal of Contemporary Legal Issues

Andrew Koppelman’s new book Burning Down the House is a guide to some of the late stages of the libertarian collapse. It’s a book whose many virtues include its clear and simple prose style. As a result of that style, and its generally straightforward exposition, I think this book will be of real use to many people, perhaps especially to free-thinking former libertarians who are engaged in a project of self-deprogramming. The book makes a nice holiday gift to the former libertarian or wavering libertarian in your life who would like to learn more about the arc of how it …

Notes From A Serf, Rachel Lu

The Journal of Contemporary Legal Issues

F. A. Hayek would have hated Obamacare. This must be distinctly understood, or nothing wonderful can come of the argument I am going to relate.

Fusionism, Not Libertarianism, Burned Down The House, Kevin Vallier

The Journal of Contemporary Legal Issues

In Burning Down the House, Andrew Koppelman has two goals: one philosophical and one sociological. The philosophical goal is to separate the wheat from the chaff in libertarian thought. Koppelman embraces the merits of F. A. Hayek’s arguments for markets. But he stridently rejects the radical libertarianism of Murray Rothbard, Robert Nozick, and Ayn Rand. The radicals are out, and the moderates are in. Hayek must increase, and Rothbard must decrease.

The sociological thesis is that radical libertarian ideology significantly influences the modern GOP and American conservatism. Koppelman sees the pathologies of the contemporary right as drawing from the …

Burning Questions: A Response To Fishkin, Long, Lu, Mack, And Vallier, Andrew Koppelman

The Journal of Contemporary Legal Issues

I’m indebted to Larry Alexander and Steve Smith for organizing this conference, and to Joseph Fishkin, Roderick Long, Rachel Lu, Eric Mack, and Kevin Vallier for their thoughtful responses to my book, Burning Down the House: How Libertarian Philosophy Was Corrupted by Delusion and Greed. When San Diego organized this conference, I gave them the names of the people whom I was most eager to engage with, scholars I admire despite some deep disagreements. They have forced me to sharpen my own views. I am very lucky.

Hermeneutic Theory And The Priority Of Constitutional Meaning, Tyler S. Moore

The Journal of Contemporary Legal Issues

Can the understanding of a law be separated from its application? Despite the increasing convergence between schools of constitutional interpretation in the United States, this question remains central. One the one side are so-called “new originalists” for whom the distinction between understanding and application (or “interpretation” and “construction” as they call it) is necessary to separate a more objective step in the interpretive process from a more subjective one. On the other are “living constitutionalists,” many of whom suggest that defining a neat boundary between these two stages is impossible. When judges decide cases, they do not (and perhaps cannot) …

The Fundamental Right To Polygynous Marriage, Ronald C. Den Otter

The Journal of Contemporary Legal Issues

This Article is about why the argument in favor of a constitutional right to polygynous marriage, predicated on the importance of personal autonomy, is considerably stronger than the sex equality arguments against it. For the most part, legal scholars have arrived late on the scene, not treating the topic with the kind of care that it deserves. Instead of relying upon equal protection analysis, I shall engage in a fundamental rights critique of opposition to polygynous marriage. In doing so, I will discuss two considerations that remain central to such analysis: the value of autonomy (understood as personal choice in …

What Is The Automotive Recycling Industry And Its Prospective Future?, Andres M. Rabago

Sustainable Supply Chain Management

An explanation of the current automotive recycling industry. Looking in depth at aspects such as its sustainability and key businesses involved in the industry and the roles they play in it.

Decompression With Intradural Dissection For The Chiari Malformation Type I: Toward Eliminating Wound Complications, Anna Lin, Lindsey Asti, Marissa Carroll, Jeffrey Campbell, Jospeh Piatt

Department of Neuroscience Faculty Papers

BACKGROUND: There is continuing conversation about surgical technique in the management of the Chiari malformation. Popular options include osseous decompression alone, decompression with dural splitting, and decompression with intradural dissection (DID) and duraplasty. Wound complications after intradural dissection are a persistent problem. The current study of an institutional series examines wound complication rates after intradural dissection without dural closure.

METHODS: A retrospective single-institution chart review was performed for patients < 21 years with Chari malformation type I who underwent DID without dural closure and had at least 6 months of follow-up. Bone removal corresponded to the area of attachment of the rectus capitis posterior minor muscles together with laminectomy of the atlas. The trapezius and semispinalis capitis muscles were retracted but were not separated from the occiput.

RESULTS: A total of 76 patients were treated from May 2010 through May 2024. Thirty-eight (50.0%) patients had syringomyelia. The median age at surgery was 9 years (interquartile range [IQR] 4-13), …

Leveraging Artificial Intelligence (Ai) To Strengthen Mtss Within Catholic Schools, Kaitlin Reichart, Adam B. Lockwood, Jessica Pizzute

Education: School of Education Faculty Publications and Other Works

Many Catholic schools face resource challenges that result in limitations surrounding the implementation of multi-tiered systems and support (MTSS). Artificial Intelligence (AI) offers a potential tool for Catholic schools to strengthen systems of support. This article explores how AI can strengthen core components of MTSS such as identifying evidence-based interventions, developing progress monitoring tools, analyzing student data, and facilitating personalized instruction. The article also outlines different AI tools available to schools and discusses potential benefits and challenges of leveraging AI within Catholic schools. Future researchers should consider evaluating and analyzing implementation of AI tools within MTSS, specifically how AI tools …

Tube-Feeding A Calf, Cheyenne Reid, Reganne K. Briggs, Melanie Heaton, Rebekah Esplin, David Secrist

All Current Publications

Producers may need to tube-feed a newborn calf to provide milk if calves are unable to nurse or suck from the nipple bottle or when calves are sick and need electrolytes. This fact sheet outlines the materials required and the steps to successfully tube-feed a calf.

Warming A Calf, Cheyenne Reid, Reganne K. Briggs, Melanie Heaton, Rebekah Esplin, David Secrist

All Current Publications

Calves born in the winter or spring are often exposed to harsh weather and environmental conditions. After birth, calves may become chilled due to cold temperatures or not being dried off promptly. A chilled calf may be experiencing hypothermia. This fact sheet explains the different types of hypothermia and methods for warming a calf until it can be safely returned outside.

Long-Term Neurocognitive And Behavioral Outcomes In Survivors Of Pediatric Brain Tumors: A Systematic Review, Tirath Patel, Pulkit Johar, Vaishnavi Kanisetti, Megan Szobody, Tori Sayers, Sriya Gullapalli, Murali Yallapu, Mushfiq Hassan Shaikh, Nikhilesh Anand, Kelsey Baker, Bharathi Gadad

School of Medicine Publications

Background: Brain tumors are among the most common neoplasms in children. These patients suffer from neurocognitive impairment, treatment-related side effects, and experience a subpar quality of life (QoL), affecting academic endeavors, social interaction, and mental wellbeing.

Methods: This review investigated different long-term neurocognitive and behavioral outcomes in pediatric brain tumor survivors and evaluated various effective treatment methods. We identified 75 relevant articles published between 2019 and 2024 using PubMed, PMC, Embase, and Google Scholar databases. Duplicates were removed, and 14 studies were finally selected following the PRISMA guidelines. Initial observations noted significant variations in the study methodologies and inclusion criteria. …

Avoiding The Thin Veneer Of Legality; Structural And Institutional Factors Impacting Judicial Scrutiny In A National Security Context, Seán Looney

School of Law, Humanities and Social Sciences

Discussions surrounding the role of judicial oversight in the national security context often revolve around discussions of appropriate standards of review and levels of deference for judges to take. While answering these doctrinal questions remains essential, the question of whether there are non-doctrinal factors which may influence how judges review executive action is relatively understudied. This article uses the so-called double-lock authorisation mechanism under the Investigatory Powers Act 2016 to show how structural and institutional factors may influence judicial decision-making in a national security context. These factors are not universal rather they are specific to the oversight mechanism in question. …

Understanding The Impact Of Employee Investigations On Those Who Lead Them: A Case Study From Nhs Wales, Andrew Jonathan Cooper, Doris Anita Behrens, Sophie Elizabeth Jones, Adrian Neal, Aled Jones, Walter Hyll

School of Nursing and Midwifery

In healthcare, there is growing awareness of the potential harm that disciplinary processes can have on employees, service delivery, and organizational culture. However, little attention has been given to the impact on those responsible for conducting these investigations. This study examines investigator harm through a cross-sectional survey, simultaneously collecting qualitative and quantitative data from 71 participants across 10 NHS Wales organizations. The findings indicate that investigators experience harm when conducting employee investigations. While those with more experience perceive themselves as better prepared to follow the formal steps of the disciplinary policy and process, their ability to prevent harm to themselves …

Reimagining Military-To-Civilian Transition: Addressing Barriers And Building Solutions, Rosalinda V. Maury, Gilly Cantor, Jeanette Harvie

Institute for Veterans and Military Families

This brief highlights key findings from IVMF research, outlines IVMF policy priorities, showcases the impact of Onward to Opportunity (O2O), and emphasizes the importance of stronger collaboration across public, private, nonprofit, and education sectors. Our goal is to inform decision-making and drive actionable solutions that reduce barriers to successful transition, improve long-term stability, and create meaningful career pathways for those who have served.

Participation Of Children And Youth With And Without Cerebral Palsy Across Settings: An Exploratory Study., Teresa Pierce, Alyssa Laforme Fiss

PCOM Scholarly Works

Background/Objective: Children with disabilities experience greater participation restrictions in life activities than children without disabilities. This study aimed to explore differences in participation of children/youth with and without cerebral palsy (CP) across home, school, and community settings, and examine participation of children with CP across gross motor function levels, age groups, gender, and income levels. Methods: This was a cross-sectional survey study of parents of children with CP (n = 20) and without CP (n = 20) over a three-month period to investigate the frequency of participation/level of involvement across settings. Participation was assessed using the Participation and …

Variability In Undergraduate Academic Stress: The Role Of Ethnicity, Early Adverse Family Experiences, And Psychological Distress, Teresa Mejia, Elana B. Gordis, Mitch Earleywine, Li Shen Chong

Faculty Research, Scholarly, and Creative Activity

Early adverse family experiences (e.g., abuse, neglect, and family conflict) can create vulnerabilities that can alter the association between psychological distress and academic stress, particularly for some ethnic groups. This study examined whether the link between psychological distress and academic stress varies in the presence of early adverse family experiences across ethnic groups. Participants (N = 284, 38.4% male, 59.5% female, 1% non-binary, and 0.7% transgender, 56.5% European American, 15.6% African American, 12.6% Hispanic and Latino, 8.5% Asian, 6.8% Mixed/Biracial) self-reported psychological distress, early adverse family experiences, and perception of academic stress. Regression analyses revealed a three-way interaction between adverse …

Biallelic Loss-Of-Function Variant In Minpp1 Causes Pontocerebellar Hypoplasia With Characteristic Severe Neurodevelopmental Disorder, Aljazi Al-Maraghi, Rulan Shaath, Katherine Ford, Waleed Aamer, Jehan Alrayahi, Sura Hussein, Elbay Aliyev, Nourhen Agrebi, Muhammad Kohailan, Satanay Z Hubrack, Sasirekha Palaniswamy, Adam D Kennedy, Karen L Debalsi, Sarah H Elsea, Ruba Benini, Tawfeg Ben-Omran, Bernice Lo, Ammira S A Akil, Khalid A Fakhro

Faculty, Staff and Students Publications

Pontocerebellar hypoplasia (PCH) encompasses a group of autosomal recessive neurodegenerative disorders marked by cerebellar and pontine atrophy. Multiple subtypes of PCH have been identified, among which the rare subtype PCH type 16 is caused by MINPP1 genetic variants. MINPPI encodes an enzyme essential for inositol polyphosphate dephosphorylation, regulating calcium and iron homeostasis. We conducted genome sequencing on a proband from the consanguineous family, who presented with a severe neurodegenerative disorder, to identify the underlying cause of disease. A comprehensive clinical assessment in addition to neuroradiological findings are described. We performed the functional validation of the identified variant and conducted untargeted …

Navigating Sovereignty And Human Rights: A Legal Analysis Of Palestinian Detention Under Israeli Jurisdiction In Comparison To International Law, Amani Nidal Odeh

Dissertations and Theses

This thesis examines whether Israeli detention practices of Palestinians conform to or contravene Israeli domestic legislation and international legal standards using a doctrinal legal analysis. This thesis evaluates six key areas through four hypotheses: the detention of minors, geographic disparities (particularly Gaza), administrative detention procedures, the use of military courts, due process violations, and detention conditions. While Israeli domestic law formally authorizes these practices, the analysis finds they routinely violate crucial international legal norms, including the ICCPR, CRC, CAT, and the Fourth Geneva Convention. The use of secret evidence, prolonged administrative detention without trial, and discriminatory legal frameworks undermines the …

The Failure Of The Annan Plan And Suggestions For Peace In Cyprus, Haley Grace Morrow

Dissertations and Theses

The following study explicates the conflict in Cyprus between the Greek Cypriots and the Turkish Cypriots. The conflict began around 70 years ago and came to its height in the 1970s when a Greek coup occurred, and subsequently, Turkey invaded the northern part of the island. This drove the two parties apart physically and mentally. The Annan Plan, a UN peace plan in 2004, attempted to bring peace to the island by reunifying the two parties into a bi-communal federation. However, this plan failed as the Greek Cypriots voted against it. The failure of the plan was primarily due to …

Preterm Birth Increases Susceptibility To Hyperglycemia Induced Glomerular Alterations In Male Mice, Aleksandra Cwiek, Kevin M Bennett, Edwin J Baldelomar, Et Al.

2020-Current year OA Pubs

Diabetic kidney disease (DKD) is the leading cause of progressive chronic kidney disease in adults in the United States. However, the impact of preterm birth on the progression of DKD has not been studied. The goal of this project was to determine the effect of preterm birth on kidney health after exposure to hyperglycemia. CD-1 pups born preterm (19 days post conception (dpc)) and term (20 dpc) were studied, and outcomes of the male mice were reported. Preterm and term mice were treated with streptozotocin at six weeks to induce hyperglycemia. Body weight and blood sugar were monitored. Histologic, molecular, …