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2024

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Disentangling Socioeconomic Status And Race In Infant Brain, Birth Weight, And Gestational Age At Birth: A Neural Network Analysis, Kathryn Sarullo, Deanna M Barch, Christopher D Smyser, Cynthia Rogers, Barbara B Warner, J Philip Miller, Sarah K England, Joan Luby, S Joshua Swamidass Jan 2024

Disentangling Socioeconomic Status And Race In Infant Brain, Birth Weight, And Gestational Age At Birth: A Neural Network Analysis, Kathryn Sarullo, Deanna M Barch, Christopher D Smyser, Cynthia Rogers, Barbara B Warner, J Philip Miller, Sarah K England, Joan Luby, S Joshua Swamidass

2020-Current year OA Pubs

BACKGROUND: Race is commonly used as a proxy for multiple features including socioeconomic status. It is critical to dissociate these factors, to identify mechanisms that affect infant outcomes, such as birth weight, gestational age, and brain development, and to direct appropriate interventions and shape public policy.

METHODS: Demographic, socioeconomic, and clinical variables were used to model infant outcomes. There were 351 participants included in the analysis for birth weight and gestational age. For the analysis using brain volumes, 280 participants were included after removing participants with missing magnetic resonance imaging scans and those matching our exclusion criteria. We modeled these …


Intrusive Traumatic Re-Experiencing Domain: Functional Connectivity Feature Classification By The Enigma Ptsd Consortium, Benjamin Suarez-Jimenez, Evan M Gordon, Et Al. Jan 2024

Intrusive Traumatic Re-Experiencing Domain: Functional Connectivity Feature Classification By The Enigma Ptsd Consortium, Benjamin Suarez-Jimenez, Evan M Gordon, Et Al.

2020-Current year OA Pubs

BACKGROUND: Intrusive traumatic re-experiencing domain (ITRED) was recently introduced as a novel perspective on posttraumatic psychopathology, proposing to focus research of posttraumatic stress disorder (PTSD) on the unique symptoms of intrusive and involuntary re-experiencing of the trauma, namely, intrusive memories, nightmares, and flashbacks. The aim of the present study was to explore ITRED from a neural network connectivity perspective.

METHODS: Data were collected from 9 sites taking part in the ENIGMA (Enhancing Neuro Imaging Genetics through Meta Analysis) PTSD Consortium (

RESULTS: rsFC signatures differentiated TE-only participants from PTSD and ITRED-only participants at about 60% accuracy. Conversely, rsFC signatures did …


Multiple Genes Core To Erad, Macroautophagy And Lysosomal Degradation Pathways Participate In The Proteostasis Response In Α1-Antitrypsin Deficiency, Jie Li, Tunda Hidvegi, Sanja Sviben, James A J Fitzpatrick, Hemalatha Sundaramoorthi, Stephen C Pak, Gary A Silverman, David H Perlmutter, Et Al. Jan 2024

Multiple Genes Core To Erad, Macroautophagy And Lysosomal Degradation Pathways Participate In The Proteostasis Response In Α1-Antitrypsin Deficiency, Jie Li, Tunda Hidvegi, Sanja Sviben, James A J Fitzpatrick, Hemalatha Sundaramoorthi, Stephen C Pak, Gary A Silverman, David H Perlmutter, Et Al.

2020-Current year OA Pubs

BACKGROUND & AIMS: In the classic form of α1-antitrypsin deficiency (ATD), the misfolded α1-antitrypsin Z (ATZ) variant accumulates in the endoplasmic reticulum (ER) of liver cells. A gain-of-function proteotoxic mechanism is responsible for chronic liver disease in a subgroup of homozygotes. Proteostatic response pathways, including conventional endoplasmic reticulum-associated degradation and autophagy, have been proposed as the mechanisms that allow cellular adaptation and presumably protection from the liver disease phenotype. Recent studies have concluded that a distinct lysosomal pathway called endoplasmic reticulum-to-lysosome completely supplants the role of the conventional macroautophagy pathway in degradation of ATZ. Here, we used several state-of-the-art approaches …


Examining The Multifaceted Impacts Of Drug Decriminalization On Public Safety, Law Enforcement, And Prosecutorial Discretion, Kelsey S. Henderson, Christopher M. Campbell, Brian C. Renauer Jan 2024

Examining The Multifaceted Impacts Of Drug Decriminalization On Public Safety, Law Enforcement, And Prosecutorial Discretion, Kelsey S. Henderson, Christopher M. Campbell, Brian C. Renauer

Criminology and Criminal Justice Faculty Publications and Presentations

This final report provides the findings of a multi-year project to understand the effects of successive drug policy efforts in Oregon. Since 2013, Oregon has implemented three changes that reclassified and lowered the seriousness of low-level drug possession offenses, with multiple years between each policy change: Justice Reinvestment in 2013, defelonization in 2017, and decriminalization in 2021. This project parses out the individual impacts of these unique events on law enforcement, prosecution, courts and sentencing, and public safety & health.


Data From: Active Transportation Counts From Existing On-Street Signal And Detection Infrastructure, Sirisha Kothuri, Patrick Allen Singleton, Mahyar Vahedi Saheli, Elizabeth Yates, Joseph P. Broach Jan 2024

Data From: Active Transportation Counts From Existing On-Street Signal And Detection Infrastructure, Sirisha Kothuri, Patrick Allen Singleton, Mahyar Vahedi Saheli, Elizabeth Yates, Joseph P. Broach

Civil and Environmental Engineering Faculty Datasets

This study’s objective was to use data from existing traffic signal infrastructure to estimate pedestrian volumes. Pedestrian push-button actuations were collected from signal controller logs at 49 intersections in western Oregon and an additional 16 intersections in eastern Oregon. These actuations were then compared to observed pedestrian counts, totaling over 34,000 people, obtained from video recordings. After exploring various options, a simple quadratic relationship was modeled using a single measure of pedestrian signal activity: the number of push-button presses (filtered to remove multiple presses within 15 seconds). The model’s predictions showed a correlation of 0.86 with observed pedestrian volumes and …


Accuracy Of True-Net In Comparison To Established White Matter Hyperintensity Segmentation Methods: An Independent Validation Study, Jeremy F Strain, Maryam Rahmani, Donna Dierker, Christopher Owen, Hussain Jafri, Andrei G Vlassenko, Kyle Womack, Jurgen Fripp, Duygu Tosun, Tammie L S Benzinger, Michael Weiner, Colin Masters, Jin-Moo Lee, John C Morris, Manu S Goyal, Adopic And Adni Investigators Jan 2024

Accuracy Of True-Net In Comparison To Established White Matter Hyperintensity Segmentation Methods: An Independent Validation Study, Jeremy F Strain, Maryam Rahmani, Donna Dierker, Christopher Owen, Hussain Jafri, Andrei G Vlassenko, Kyle Womack, Jurgen Fripp, Duygu Tosun, Tammie L S Benzinger, Michael Weiner, Colin Masters, Jin-Moo Lee, John C Morris, Manu S Goyal, Adopic And Adni Investigators

2020-Current year OA Pubs

White matter hyperintensities (WMH) are nearly ubiquitous in the aging brain, and their topography and overall burden are associated with cognitive decline. Given their numerosity, accurate methods to automatically segment WMH are needed. Recent developments, including the availability of challenge data sets and improved deep learning algorithms, have led to a new promising deep-learning based automated segmentation model called TrUE-Net, which has yet to undergo rigorous independent validation. Here, we compare TrUE-Net to six established automated WMH segmentation tools, including a semi-manual method. We evaluated the techniques at both global and regional level to compare their ability to detect the …


The Evolving Role Of Libraries In The Fourth Industrial Revolution: Navigating Digital Transformation, Abdullahi Olayinka Isiaka, Abdulfatai Soliu, Biliamin Abiola Aremu, Benjamin Adebisi Bamidele, Saidu Saba-Jibril, Adelani Rotimi Ibitoye Jan 2024

The Evolving Role Of Libraries In The Fourth Industrial Revolution: Navigating Digital Transformation, Abdullahi Olayinka Isiaka, Abdulfatai Soliu, Biliamin Abiola Aremu, Benjamin Adebisi Bamidele, Saidu Saba-Jibril, Adelani Rotimi Ibitoye

Library Philosophy and Practice (e-journal)

Abstract

This article explores the transformative impact of the Fourth Industrial Revolution (4IR) on libraries and their pivotal role in navigating the challenges and opportunities brought forth by rapid technological advancements. Libraries, traditionally perceived as repositories of books and information, are undergoing a profound metamorphosis in the digital age. The 4IR, characterized by breakthroughs in Artificial Intelligence, the Internet of Things, and Data Analytics, demands a redefinition of the library’s purpose and services. The first section introduces the concept of the 4IR and its key technological advancements. Emphasis is placed on understanding the dynamic landscape of the 4IR and the …


Targeting Of Oncogenic Aaa-Atpase Trip13 Reduces Progression Of Pancreatic Ductal Adenocarcinoma, Farrukh Afaq, Sumit Agarwal, Prachi Bajpai, Sameer Al Diffalha, Hyung-Gyoon Kim, Shajan Peter, Moh'd Khushman, Subhash C Chauhan, Priyabrata Mukherjee, Sooryanarayana Varambally, Upender Manne Jan 2024

Targeting Of Oncogenic Aaa-Atpase Trip13 Reduces Progression Of Pancreatic Ductal Adenocarcinoma, Farrukh Afaq, Sumit Agarwal, Prachi Bajpai, Sameer Al Diffalha, Hyung-Gyoon Kim, Shajan Peter, Moh'd Khushman, Subhash C Chauhan, Priyabrata Mukherjee, Sooryanarayana Varambally, Upender Manne

2020-Current year OA Pubs

Thyroid hormone receptor-interacting protein 13 (TRIP13) is involved in cancer progression, but its role in pancreatic ductal adenocarcinoma (PDAC) is unknown. Thus, we assessed the expression, functional role, and mechanism of action of TRIP13 in PDAC. We further examined the efficacy of TRIP13 inhibitor, DCZ0415, alone or in combination with gemcitabine on malignant phenotypes, tumor progression, and immune response. We found that TRIP13 was overexpressed in human PDACs relative to corresponding normal pancreatic tissues. TRIP13 knockdown or treatment of PDAC cells with DCZ0415 reduced proliferation and colony formation, and induced G2/M cell cycle arrest and apoptosis. Additionally, TRIP13 knockdown or …


Environmental Law: The Negotiable Implementation Of Environmental Law, Dave Owen Jan 2024

Environmental Law: The Negotiable Implementation Of Environmental Law, Dave Owen

The Judges' Book

No abstract provided.


Predictability And Adaptation In Law And Other Markets (Chapter In A Coming Book: Research Handbook On Law And Time), Saul Levmore Jan 2024

Predictability And Adaptation In Law And Other Markets (Chapter In A Coming Book: Research Handbook On Law And Time), Saul Levmore

Coase-Sandor Institute for Law & Economics Research Paper Series

People and enterprises that are subject to the law find it useful to know what the law is at present, but then also to anticipate future rules. If laws are stable this is easily done. Stability is more common where the judicial branch is concerned, because precedents are often valued, and for good reason. They are more often followed by judges than by those involved in other methods of lawmaking. But in all of lawmaking, and even in the private sphere, there is value to consistency and certainty. And yet, surprises can be attractive if they are not confronted on …


Optimizing Neural Networks For Iiot Attack Detection, Hamad Alblooshi Jan 2024

Optimizing Neural Networks For Iiot Attack Detection, Hamad Alblooshi

Theses

The Industrial Internet of Things (IIoT) stands as a revolutionary force, intertwining physical devices, sensors, and industrial systems to usher in advanced automation and data-driven decision-making across various sectors. However, this increased connectivity has exposed these systems to a growing array of cyber threats. Safeguarding IIoT environments becomes crucial to maintain the integrity, availability, and confidentiality of critical industrial processes. In response, this research explores the optimization of neural network parameters using Genetic Algorithms (GA). The application of GA has led to achieve a remarkable accuracy of 95% across various attack types. The results demonstrate a high performance in identifying …


Chapter 17. Approaches To Inclusive Recruitment: Practical And Hopeful, Adriana Poo, Anamika Megwalu, Nick Szydlowski, Kathryn Blackmer Reyes, Peggy Cabrera, Ann Agee Jan 2024

Chapter 17. Approaches To Inclusive Recruitment: Practical And Hopeful, Adriana Poo, Anamika Megwalu, Nick Szydlowski, Kathryn Blackmer Reyes, Peggy Cabrera, Ann Agee

Faculty Research, Scholarly, and Creative Activity

San José State University (SJSU) is located in downtown San José, a city of over one million residents in California’s San Francisco Bay Area. Established in 1857, SJSU is the oldest public university on the west coast of the United States. It is also the founding campus of the California State University (CSU) system that comprises twenty-three campuses, making it the largest four-year public university system in the country. SJSU has nine colleges and sixty-seven departments, which offer bachelor’s, master’s, and a growing number of doctoral degree programs. It enrolls over 36,000 students and employs more than 2,100 faculty members. …


Machine Learning Based Solutions For Detecting Social Media Spam And Phishing Incidents, Ahmed Al Shehhi Jan 2024

Machine Learning Based Solutions For Detecting Social Media Spam And Phishing Incidents, Ahmed Al Shehhi

Theses

The growing digital interactions across various social media platforms increases the risks of phishing schemes and spam messages that compromise personal and organisational security. This thesis tackles such threats with the aid of machine learning and natural processing techniques that are utilized for detecting malicious communications with high accuracy. A total of three datasets were used in this study, two for phishing and one for spam. The research aims to explore the performance of classification models, including Logistic Regression, Support Vector Machine, Naïve Bayes, and Linear Discriminant Analysis, as well as a hybrid model combining Logistic Regression and Naïve Bayes. …


Integration Of Blockchain And Cryptographic Techniques For Location Based Services, Rashed Al Shamali Jan 2024

Integration Of Blockchain And Cryptographic Techniques For Location Based Services, Rashed Al Shamali

Theses

As digital systems continue to evolve in complexity, protecting user identities and ensuring the secure transmission of data has become paramount. Conventional techniques such as passwords and digital signatures are often insufficient to address modern security threats unless paired with more sophisticated technologies. This thesis proposes a framework that integrates Blockchain Technology with Elliptic Curve Cryptography (ECC) to fortify identity verification protocols and enhance location-obscuring methods. Blockchain’s inherent features of decentralization, immutability, and non-repudiation makes it an ideal platform for secure data exchange. When combined with ECC, which provides robust encryption with smaller key sizes, the system achieves a heightened …


The Uae’S Readiness For Technology Export: The Case Of Ai, Reem Tamer Aldandashi Jan 2024

The Uae’S Readiness For Technology Export: The Case Of Ai, Reem Tamer Aldandashi

Theses

Export diversification is one way for the UAE to sustain and flourish its economy. Although UAE is an oil-rich country, it needs to search for and incubate future exports besides the existing ones to keep the wheel of the economy moving, increase the employment rate, and strengthen the country from any future economic strokes. While looking at the technology spread and Artificial Intelligence (AI) focus and efforts in UAE, much research investigated the outcomes of digitization on the UAE economy and its technological strength and competitiveness. At the same time, no one has searched for the possibility of having one …


[Review Of] Abolition Geography, By Ruth Wilson Gilmore, Jennifer Rycenga Jan 2024

[Review Of] Abolition Geography, By Ruth Wilson Gilmore, Jennifer Rycenga

Faculty Research, Scholarly, and Creative Activity

No abstract provided.


Ownership Topology Of Vertically-Scaled Agile, William Dabney Jan 2024

Ownership Topology Of Vertically-Scaled Agile, William Dabney

Theses

Much as Scrum, Kanban, and XP are used to structure team-level agility, those wishing to take agility beyond the team level often turn to proven solutions. The most popular, which aim to scale development by adding teams under a shared collective ownership rather than separating them into discrete units, are the Scaled Agile Framework (SAFe), Large Scale Scrum (LeSS), and Nexus. These frameworks advocate for aligning ownership subdivisions along features rather than code, which allows teams working on the same product to do so autonomously. While the benefits of this have been researched, the topology of ownership in these frameworks …


The Statewide Standard, 2024, College Of Education Jan 2024

The Statewide Standard, 2024, College Of Education

The Statewide Standard

No abstract provided.


Maximizing The Number Of H-Colorings Of Graphs With A Fixed Minimum Degree, John Engbers Jan 2024

Maximizing The Number Of H-Colorings Of Graphs With A Fixed Minimum Degree, John Engbers

Mathematical and Statistical Science Faculty Research and Publications

For graphs G and H, an H-coloring of G is an adjacency-preserving map from the vertex set of G to the vertex set of H.


A Model For Community-Driven Development Of Best Practices: The Ocean Observatories Initiative Biogeochemical Sensors Data Best Practices And User Guide, Hilary I. Palevsky, Sophie Clayton, Heather Benway, Mairead Maheigan, Dariia Atamanchuk, Roman Battisi, Jennifer Batryn, Annie Bourbonnais, Ellen M. Briggs, Filipa Carvalho, Alison P. Chase, Rachel Eveleth, Rob Fatland, Kristen E. Fogaren, Jonathan Peter Fram, Susan E. Hartman, Isabela Le Bras, Cara C. M. Manning, Joseph A. Needoba, Merrie Beth Neely, Hilde Oliver, Andrew C. Reed, Jennie E. Rheuban, Christina Schallenberg, Ian Walsh, Christopher Wingard, Kohen Bauer, Baoshen Chen, Jose Cuevas, Susana Flecha, Micah Horwith, Melissa Melendez, Tyler Menz, Sara Rivero-Calle, Nicholas P. Roden, Tobias Steinhoff, Paulo Nicolás Trucco-Pignata, Michael F. Vardaro, Meg Yoder Jan 2024

A Model For Community-Driven Development Of Best Practices: The Ocean Observatories Initiative Biogeochemical Sensors Data Best Practices And User Guide, Hilary I. Palevsky, Sophie Clayton, Heather Benway, Mairead Maheigan, Dariia Atamanchuk, Roman Battisi, Jennifer Batryn, Annie Bourbonnais, Ellen M. Briggs, Filipa Carvalho, Alison P. Chase, Rachel Eveleth, Rob Fatland, Kristen E. Fogaren, Jonathan Peter Fram, Susan E. Hartman, Isabela Le Bras, Cara C. M. Manning, Joseph A. Needoba, Merrie Beth Neely, Hilde Oliver, Andrew C. Reed, Jennie E. Rheuban, Christina Schallenberg, Ian Walsh, Christopher Wingard, Kohen Bauer, Baoshen Chen, Jose Cuevas, Susana Flecha, Micah Horwith, Melissa Melendez, Tyler Menz, Sara Rivero-Calle, Nicholas P. Roden, Tobias Steinhoff, Paulo Nicolás Trucco-Pignata, Michael F. Vardaro, Meg Yoder

OES Faculty Publications

The field of oceanography is transitioning from data-poor to data-rich, thanks in part to increased deployment of in-situ platforms and sensors, such as those that instrument the US-funded Ocean Observatories Initiative (OOI). However, generating science-ready data products from these sensors, particularly those making biogeochemical measurements, often requires extensive end-user calibration and validation procedures, which can present a significant barrier. Openly available community-developed and -vetted Best Practices contribute to overcoming such barriers, but collaboratively developing user-friendly Best Practices can be challenging. Here we describe the process undertaken by the NSF-funded OOI Biogeochemical Sensor Data Working Group to develop Best Practices for …


Barriers And Variable Spacing Enhance Convective Cooling And Increase Power Output In Solar Pv Plants, Brooke Stanislawski, Todd Harman, Raul Bayoan Cal, Marc Calaf Jan 2024

Barriers And Variable Spacing Enhance Convective Cooling And Increase Power Output In Solar Pv Plants, Brooke Stanislawski, Todd Harman, Raul Bayoan Cal, Marc Calaf

Mechanical and Materials Engineering Faculty Publications and Presentations

When the temperature of solar photovoltaic (PV) modules rises, efficiency drops and module degradation accelerates. Thus, it is beneficial to reduce module operating temperatures. Previous studies of solar power plants have illustrated that incoming flow characteristics, turbulent mixing, and array geometry can strongly impact convective cooling, as measured by the convective heat transfer coefficient h. In the fields of heat transfer and plant canopy flow, previous work has shown that system-scale arrangement modifications—e.g., variable spacing, barriers, or windbreaks—can passively alter the flow, enhance turbulent mixing, and influence convection. However, researchers have not yet explored how variable spacing or barriers …


Experimental And Modeled Assessment Of Interventions To Reduce Pm2.5 In A Residence During Awildfire Event, Chrissi Argyro Antonopoulos, H. E. Dillon, Elliott T. Gall Jan 2024

Experimental And Modeled Assessment Of Interventions To Reduce Pm2.5 In A Residence During Awildfire Event, Chrissi Argyro Antonopoulos, H. E. Dillon, Elliott T. Gall

Mechanical and Materials Engineering Faculty Publications and Presentations

Increasingly large and frequent wildfires affect air quality even indoors by emitting and dispersing fine/ultrafine particulate matter known to pose health risks to residents. With this health threat, we are working to help the building science community develop simplified tools that may be used to estimate impacts to large numbers of homes based on high-level housing characteristics. In addition to reviewing literature sources, we performed an experiment to evaluate interventions to mitigate degraded indoor air quality. We instrumented one residence for one week during an extreme wildfire event in the Pacific Northwest. Outdoor ambient concentrations of PM2.5 reached historic …


Revisiting Rockafellar’S Theorem On Relative Interiors Of Convex Graphs With Applications To Convex Generalized Differentiation, Boris S. Mordukhovich, Nguyen Mau Nam, Dang Van Cuong, G. Sandine Jan 2024

Revisiting Rockafellar’S Theorem On Relative Interiors Of Convex Graphs With Applications To Convex Generalized Differentiation, Boris S. Mordukhovich, Nguyen Mau Nam, Dang Van Cuong, G. Sandine

Mathematics and Statistics Faculty Publications and Presentations

In this paper we revisit a theorem by Rockafellar on representing the relative interior of the graph of a convex set-valued mapping in terms of the relative interior of its domain and function values. Then we apply this theorem to provide a simple way to prove many calculus rules of generalized differentiation for set-valued mappings and nonsmooth functions in finite dimensions. Using this important theorem by Rockafellar allows us to improve some results on generalized differentiation of set-valued mappings in [13] by replacing the relative interior qualifications on graphs with qualifications on domains and/or ranges.


Proof Of The Kresch-Tamvakis Conjecture, John Caughman, Taiyo S. Terada Jan 2024

Proof Of The Kresch-Tamvakis Conjecture, John Caughman, Taiyo S. Terada

Mathematics and Statistics Faculty Publications and Presentations

In this paper we resolve a conjecture of Kresch and Tamvakis.


Families At The Center: Leading For Home Visiting Systems Change, Callie H. Lambarth, Beth L. Green, Center For Coordinating Oregon Home Visiting Systems Jan 2024

Families At The Center: Leading For Home Visiting Systems Change, Callie H. Lambarth, Beth L. Green, Center For Coordinating Oregon Home Visiting Systems

Center for Improvement of Child and Family Services Publications

The Center for Coordinating Oregon Home Visiting Systems (CCOHVS) launched in February 2024 at the Center for Improvement of Child and Family Services at Portland State University. The CCOHVS functions as a program-neutral backbone organization for a coordinated system of prenatal and early childhood home visiting services. Its work will move the state closer to the vision described in the Raise Up Oregon 2.0 (RUO) strategic plan1 for early childhood systems, namely to create “equitable, integrated, accessible, inclusive, anti-racist and family-centered” early learning services, with a focus on ensuring this system meets the needs of pregnant people and families with …


Non-Surgical Treatment Options For Male-Pattern Baldness, Robert Schiffer Jan 2024

Non-Surgical Treatment Options For Male-Pattern Baldness, Robert Schiffer

The Science Journal of the Lander College of Arts and Sciences

Male pattern baldness affects nearly 50% of the world’s male population. It is associated with physiological conditions such as cardiovascular disease as well as psychological issues with self-image and self-esteem. Although surgical treatments exist, they are associated with risks and complications. Various non-surgical treatment modalities for male pattern baldness are available for patients. Topical and oral formulations of minoxidil, finasteride, and dutasteride can be used, in addition to low level light therapy (LLLT) and platelet rich plasma (PRP) therapy. As many treatment options exist, it may be challenging for patients to decide which to choose. Although there have been few …


The Effects Of Electronic Cigarettes On The Oral Cavity, Batsheva Saposh Jan 2024

The Effects Of Electronic Cigarettes On The Oral Cavity, Batsheva Saposh

The Science Journal of the Lander College of Arts and Sciences

Electronic cigarettes, which became available for purchase in the United States in 2007, were initially touted as a harmless aid for smoking cessation. However, recent research into the impact of electronic cigarettes on the human body has shown potential deleterious effects. This paper aims to examine the effects electronic cigarette usage has on the oral cavity. The methods to compile research involved reading through many peer-reviewed articles to analyze the most current information on the topic. The findings indicate several potentially adverse effects on the oral cavity including oral cancer, periodontitis, dental caries, xerostomia, facial fractures, failed dental implants, and …


Ethanol-Containing Mouthwash: Is It Safe? Exploring The Potential Risks And Benefits, Michoel Adler Jan 2024

Ethanol-Containing Mouthwash: Is It Safe? Exploring The Potential Risks And Benefits, Michoel Adler

The Science Journal of the Lander College of Arts and Sciences

This thesis investigates the safety of ethanol-containing mouthwash, focusing on the risks and benefits associated with the ethanol in mouthwash and its metabolic product, acetaldehyde. While ethanol is an effective antimicrobial agent, its carcinogenic and cytotoxic effects raise some concerns. This paper examines ethanol and acetaldehyde exposure, its toxicity, and its effects on oral health. Existing studies have found risks associated with ethanol exposure and have not found decreased effectiveness in ethanol-free mouthwash controlling oral bacteria. Further research is needed to determine the exact risks associated with ethanol-containing mouthwash and should focus on identifying the most effective and safest combination …


Overview Of Weight Loss Medications, Malky Mandel Jan 2024

Overview Of Weight Loss Medications, Malky Mandel

The Science Journal of the Lander College of Arts and Sciences

Obesity is a complex medical condition that is multifactorial in origin. About one-third of adults in the United States are obese, and another third are overweight (Ogden et al., 2007). Obesity is associated with a multitude of comorbidities, such as cardiovascular disease, diabetes mellitus, and osteoarthritis (Lim, Boster, 2023). Additionally, obesity may cause psychological disorders due to social prejudice and discrimination toward obese people (Wadden et al. 2002). Economically, obesity is also a tremendous financial burden (Tremmel et al. 2017). It is estimated that the overall cost of obesity-related illness in the US is nearly $500 billion (Cawley et al., …


Extraordinary Punishment: Conditions Of Confinement And Compassionate Release, Meredith B. Esser Jan 2024

Extraordinary Punishment: Conditions Of Confinement And Compassionate Release, Meredith B. Esser

Scholarly Works

People experience severe forms of harm while incarcerated, including medical neglect, prolonged solitary confinement, sexual and physical violence, and a host of other ills. But civil rights litigation under the Eighth Amendment the most common vehicle through which people seek to redress these harms presents significant practical and doctrinal barriers to incarcerated plaintiffs. Most notably, the Eighth Amendment's "deliberate indifference" standard asks not whether a person has been harmed, but instead requires plaintiffs to demonstrate a criminally reckless mental state on the part of prison officials. Further, Eighth Amendment remedies are limited to damages or injunctions, which may not adequately …