Digital Commons Network^™

Navigating The Complexity Of Braf Mutations In Non-Small Cell Lung Cancer: Current Insights And Future Prospects, Sufyan Ibrahim, Smita Shenoy, Ramya Kateel, Shreya Hegde

Open Access archive

There are many challenges that are faced in the treatment of Non-Small Cell Lung Cancer (NSCLC) due to the complexities associated with the tumor. Association of different types of mutations are one of the major complexities. Among these mutations, BRAF mutations are significantly gathering more attention due to their impact on disease progression and therapeutic response. This review provides an analysis of the current understanding of BRAF mutations in NSCLC, focusing on the molecular intricacies, clinical implications, and therapeutic advancements. The article explores the diverse spectrum of BRAF mutations, highlighting the prevalence of specific mutations such as V600E and non-V600E …

Delivery Of Nutraceutical Products In Sports, Hrithik Dadasaheb Jadhav, Anjana A. Kailas, Annamalai Rama, Induja Govindan

Open Access archive

Healthy interventions are one of the most significant aspects of first-rate athletic execution. Combat-related tasks necessitate the greatest ratio of muscular tissue to body weight in order to reach the highest level of command feasible. An adequate level of nutrition knowledge is essential, especially when it comes to assessing energy requirements while avoiding misunderstandings about dietary supplements and incorrect assessments of steroid requirements, which could damage health. In that framework, our organization seeks to emphasize healthy needs and assess the importance of a daily diet in combat athletes, which gradually involves a wide variety of sporting food nutrients, and the …

A Brief Exploration Of Artificial Intelligence In Dental Healthcare: A Narrative Review, Prakrati Kamath, Prathvi Kamath, Sharon J.R. Saldanha, Thilak B. Shetty

Open Access archive

Artificial intelligence is a computer system which can replicate human behavior and largely supports human actions and interpretation, but not replace human responses. Over the past few decades, the field of artificial intelligence (AI) has experienced phenomenal development and expansion. We are surrounded by several instances of AI. AI has applications in different branches of Dentistry. A total of 59 papers from an electronic search using Google Scholar and PubMed were used to create this narrative review. Artificial intelligence can be utilised for diagnosis, decision-making, treatment planning, early detection and prevention of oral disease, and finally result prediction by utilising …

Effect Of Treadmill Exercise On The Liver, Kidney Health, And Serum Il-10 Levels In High-Fat Diet-Induced Obese Male Wistar Rats, Samreen M. Sheik, H. Madhukar Mallya, Deepak Nayak Manel, Karkala Sreedhara Ranganath Pai

Open Access archive

This study investigated the impact of treadmill exercise on liver and kidney health in obese rats induced by a high-fat diet (HFD), alongside serum IL-10 levels. Rats were divided into normal control, HFD, HFD with atorvastatin, and HFD with exercise groups. Obesity was induced over 11 months via the HFD, while the exercise group underwent treadmill training three times per week for 90 days. Parameters measured included body weight, lipid profile, liver and kidney function tests, rat interleukine-10, and histopathology of the liver and kidney. Significant increases in body weight, lipid profile, and liver and kidney function tests, alongside decreased …

Mobile Health (Mhealth) Interventions For Health Promotion During The Perinatal Period In India: A Scoping Review, Zara Small, Sophie Elizabeth Thompson, Ankita Sharma, Sreya Majumdar

Open Access archive

Introduction: Perinatal and maternal mortality rates remain high in India compared to global levels, and there is significant heterogeneity in outcomes across Indian states. Many mobile health (mHealth) interventions have been developed to improve maternal and infant health outcomes in India, however it is unclear how mHealth can best support women in this culturally and resource diverse setting. Therefore, we aimed to identify mHealth interventions targeting women and their families in the perinatal period in India, identify barriers and facilitators to their uptake, and future research directions. Methods: The Preferred Reporting Items for Systematic Reviews and Meta-Analyses and Joanna Briggs …

Efficacy Of Lycium Barbarum (Goji Berry) Mouthwash For Managing Periodontitis: A Randomized Clinical Trial, Amee Sanghavi, Laasya Shettigar, Aditi Chopra, Ashmeet Shah

Open Access archive

Background: Removal of the microbial deposits (plaque and calculus) by performing effective scaling and root planing (SRP) is the fundamental step for managing periodontal disease (gingivitis and periodontitis). Various adjuncts in the form of mouthwash, gels, and toothpaste are also being used as adjuncts to SRP for managing periodontitis. Recently, Lycium barbarum (L. barbarum), commonly known as goji berry or wolfberry, has gained popularity for managing chronic inflammatory and infectious diseases. However, its efficacy in managing periodontitis has never been explored. Hence the present study aims to evaluate the efficacy of goji berry mouthwash compared to chlorhexidine mouthwash for managing …

Concepts In Animal Parasitology, Chapter 47: Summary Of The Digenea (Subclass): Insights And Lessons From A Prominent Parasitologist [Platyhelminthes, Trematoda, Digenea], Robin M. Overstreet

Concepts in Animal Parasitology

An overview of the digenean trematodes (subclass Digenea) including insights and lessons from a prominent parasitologist, Robin M. Overstreet. Includes discussion of general morphology, biology, preparation methods, phylogeny, classification, life cycles, host-digenean relationships, effects on host behavior, hyperparasitism, ecology, digeneans as indicators, and literature on the digeneans.

Chapter 47 in Concepts in Animal Parasitology, by Robin M. Overstreet. 2024. S. L. Gardner and S. A. Gardner, editors. Zea Books, Lincoln, Nebraska, United States. doi: 10.32873/unl.dc.ciap047

Nebline, January/February 2024

NEBLINE Newsletter Archive from Nebraska Extension in Lancaster County

2023 Extension Highlights

4-H Programs Engaged 39,421 Youth

Nebraska Extension’s Strategic Direction

Enjoy a Comforting Bowl of Soup in January & Beyond by Kayla Colgrove

Recipe of the Month: Multi-Cooker Tuscan Soup by Kayla Colgrove

Garden Guide: Things to Do This Month

Extension’s 2024 Master Gardener Volunteer Training Begins Soon

Upcoming Green Industry Conferences

ProHort Lawn & Landscape Update

2024 Pesticide Applicator Trainings

Crop Production Clinics

Extension Workshop Planned on Managing Farmland and Transition Planning

Water Quality: Nebraska On-Farm Research by John Nelson

House Centipedes by Kait Chapman

Early Childhood Prep Academy: Leaders Today, Learners Tomorrow by Hayley Jackson

Heart …

Why Is There No Social Citizenship In Puerto Rico? The Demise Of Section 20, Haley Powell

Indiana Journal of Law and Social Equality

Part I will define T.H. Marshall’s theory of citizenship rights and explain how that framework pertains to the denial of social welfare rights in Puerto Rico’s constitution. It will also delineate the larger context of social welfare in the United States using the contract versus charity paradigm posited by two historians, New School Professor Nancy Fraser and New York University Professor Linda Gordon. Part II will explore the legislative history of the Puerto Rican Constitution at the Puerto Rican Constitutional Convention and the U.S. Congress debates following the convention. Part III will examine the ramifications of the removal of Section …

Quality & Credibility Ff Adhd Information On Social Media And Adhd Help-Seeking Intentions, Saara Zakkiya Nasruddin

Electronic Theses and Dissertations

Background: There is an increased prevalence of adult Attention-deficit/hyperactivity disorder (ADHD), and stimulant prescription use in the United States, especially when compared to years prior to 2020. Due to accessibility and popularity of ADHD on social media, many individuals gain information on ADHD from these sources. People may view information on social media as credible due to its ability to provide connection, community, and empowerment. However, content analyses of ADHD information on social media show the quality of content on social media is poor. These content analyses utilized outdated quality evaluation tools that are not specific for social media. Principles …

Isolation Of Novel Myxobacteria And Progress Towards Heterologous Expression Of Uncharacterized Secondary Metabolites, Andrew Ahearne

Electronic Theses and Dissertations

Myxobacteria, first observed by Roland Thaxter in the late 19th century, are known for their unique swarming behavior, complex fruiting body formation and biosynthetic potential. Myxobacteria are noted for their large genomes and the presence of numerous biosynthetic gene clusters (BGCs) that hint at their potential to produce novel metabolites with therapeutic properties. Isolation of myxobacteria utilizing E. coli and filter paper baiting yielded 20 myxobacteria isolated from rhizospheric soil samples in North America. Among these isolates, nine were identified as novel species, representing the genera Archangium, Myxococcus, Nannocystis, Polyangium, Pyxidicoccus, Sorangium, and Stigmatella. Comprehensive growth profiles, biochemical assays, and …

Linguistic Uniscape : A Comparative Study Of Universities In Thailand, Zhaoyi Pan

Manusya, Journal of Humanities

This study examines the linguistic landscape (ll) of university campuses in Thailand and proposes the term “linguistic uniscape” (lu). It attempts to examine whether there is a significant difference in the code preference for signage between the public universities (puu s) and the private universities (pru s) in Thailand and examines the different social meanings of the signage at the puu s and at the pru s by using place semiotics (ps) theory. A total of 30 university campuses were investigated, including 15 puu s and 15 pru s. The results revealed a significant difference in the use of English …

Molecular And Cellular Programs Underlying The Development Of Bovine Pre-Implantation Embryos, Zongliang Jiang

Faculty Publications

Early embryonic mortality is a major cause of infertility in cattle, yet the underlying molecular causes remain a mystery. Over the past half century, assisted reproductive technologies such as in vitro fertilisation and somatic cell nuclear transfer have been used to improve cattle reproductive efficiency; however, reduced embryo developmental potential is seen compared to their in vivo counterparts. Recent years have seen exciting progress across bovine embryo research, including genomic profiling of embryogenesis, new methods for improving embryo competence, and experimenting on building bovine embryos from stem cell cultures. These advances are beginning to define bovine embryo molecular and cellular …

Dietary Intakes Of Branch Chained Amino Acids And Obesity Risk Among Chinese Gestational Diabetes Women, Xiaoyun Yang, Weiqin Li, Wei Li, Huikun Liu, Leishen Wang, Junhong Leng, Yuxin Fan, Xilin Yang, Ming Liu, Gang Hu

Population and Public Health Science Faculty Publications

Introduction: Epidemiological studies have assessed the correlation between daily dietary branch chain amino acid (BCAA) intakes and the risk of obesity, however, the findings from these studies were inconsistent and investigations among GDM women were few. Objective: The present study was to investigate the associations of daily BCAA intakes with the risks of overweight and abdominal obesity among women with prior gestational diabetes mellitus (GDM) postpartum. Method: We performed a cross-sectional study of 1,263 women with prior GDM at 1–5 years post-delivery. Logistic regression models were used to estimate the associations of daily dietary intakes of BCAAs with the risks …

Variant Of The Lactase Lct Gene Explains Association Between Milk Intake And Incident Type 2 Diabetes, Kai Luo, Guo Chong Chen, Yanbo Zhang, Jee Young Moon, Jiaqian Xing, Brandilyn A. Peters, Mykhaylo Usyk, Zheng Wang, Gang Hu, Jun Li, Elizabeth Selvin, Casey M. Rebholz, Tao Wang, Carmen R. Isasi, Bing Yu, Rob Knight, Eric Boerwinkle, Robert D. Burk, Robert C. Kaplan, Qibin Qi

Population and Public Health Science Faculty Publications

Cow’s milk is frequently included in the human diet, but the relationship between milk intake and type 2 diabetes (T2D) remains controversial. Here, using data from the Hispanic Community Health Study/Study of Latinos, we show that in both sexes, higher milk intake is associated with lower risk of T2D in lactase non-persistent (LNP) individuals (determined by a variant of the lactase LCT gene, single nucleotide polymorphism rs4988235) but not in lactase persistent individuals. We validate this finding in the UK Biobank. Further analyses reveal that among LNP individuals, higher milk intake is associated with alterations in gut microbiota (for example, …

Efficient Design Of Neural Network Hardware Accelerator For Enhanced Performance In Deep Learning Systems, Tamador Nadem Mohaidat

Electronic Theses and Dissertations

Artificial intelligence (AI) hardware accelerator is an emerging research for several applications and domains. The hardware accelerator aims to provide high computational speed while retaining low cost and high learning performance. The main challenge is to design complex machine learning models on hardware with high performance. In this thesis, the aim is to develop the hardware implementation of perceptron within a neural network. Innovative hardware-based approaches are explored to optimize perceptron networks, enhancing accuracy, reliability, and fault tolerance while minimizing resource requirements and power consumption.

A thorough investigation into machine learning accelerators and associated challenges was initially conducted. The hardware …

Tanzanian Cyberscape: Exploring Language Preference Patterns Among Instagram Users, Carolyne Saria Ulomy

Electronic Theses and Dissertations

Virtual platforms such as Instagram are not only characterized by massive collaboration, sharing, and access to information but also by multilingual exchanges. For example, Tanzanian social media users choose to disseminate or publish information online using different languages present in their linguistic repertoires. This study explores multilingualism in social media (Instagram) within the Tanzanian context, as well as address the statuses of Swahili, English, Swanglish/Kiswanglish, Community Languages (CLs) and Foreign Languages (FLs) on social media. Specifically, the research investigated two overarching questions: What are the factors influencing language choices among Tanzanian Instagram users? and is there an association between content …

A Republic Of Spending, Jonathan S. Gould

Faculty Articles

Large-scale spending measures make up many of Congress’s most important recent contributions to national policymaking. Congress has appropriated trillions of dollars to respond to emergencies, fight climate change, expand social safety net programs, spur technological innovation, and strengthen national infrastructure. While the contemporary Congress’s failure to enact landmark regulatory statutes causes many to characterize it as dysfunctional, Congress in fact remains quite active—its policymaking energy is simply concentrated in the spending domain. Congress’s use of spending rather than regulatory legislation as its primary way of shaping national policy marks a significant shift in American governance. This Article examines the causes …

Racial Disparities In Snap Receipt For Eligible Asian Americans In Massachusetts, Sokha Eng, Weichun Yan, Brian Beauregard, Susan R. Crandall

Center for Social Policy Publications

Despite qualifying as income eligible, many Massachusetts families do not access SNAP (Supplemental Nutrition Assistance Program) benefits. Due to the sharp increase in the cost of living, especially the cost of housing and food expenses, more families are facing food insecurity. Thus, it is critical to ensure that families in need receive SNAP benefits. While previous studies have examined racial disparities, there is a limited focus on Asian American families. Even fewer studies disaggregate data to explore disparities among Asian American ethnic subgroups. Further, few studies have addressed disparities in SNAP receipt specifically for income eligible families.

The purpose of …

Assessing The Acquisition Of Romani In Roma Children, Hirsto Kyuchukov, Jill De Villiers, Yanwan Zhu, Iris Zhong

Psychology: Faculty Publications

The paper presents the first comprehensive look at the language development of Romani-speaking children from resource-poor Roma communities in several European countries. 250 participants aged 3- to 10-years participated. The experimental tasks assess knowledge in eight key areas of grammar and morphology, including fast mapping of novel items. The special properties of Romani allow new insights on long distance wh-movement and possessive agreement, and the data question the universality of other distinctions in passives and wh-movement from complements. The results demonstrate that the Roma children as a group are as proficient in their primary language as children in other countries, …

Careful Communication: A Confrontation Of Cartesian Mind/Body Dualism And Western Perceptions Of Intelligence In The Dance Classroom, Sarah Lunceford

Dance (MFA) Theses

Western perceptions of intelligence in correlation with Cartesian Mind/Body Dualism can have a detrimental impact on the way students receive and are affected by information. In collegiate settings where students participate in Western concert dance technique classrooms and dance academic courses, a student’s reputation for excelling in one area or another can influence the teacher’s perception of the student’s abilities. This can cause instructors to presume a generalized understanding of what a student is capable of and encourage an unbalanced engagement with the student’s abilities within one type of classroom versus another. This work considers the author's experience within dance …

Environmental Health And Impact Of Workload On Errors For Wildland Fire Personnel, Michael Bryan Held

Masters Theses

"This thesis offers an analysis of how environmental health and workload affect wildland fire dispatchers and firefighters, combining results from two studies. The first study, "Environmental Health of Wildland Firefighters: A Scoping Review," performs a scoping review of scientific literature that examines the unique environmental health challenges wildland firefighters face. The review points out the increased risks to safety, health, and well-being from more exposure to natural hazards, identifying key research gaps and priorities. It stresses the need to broaden the geographic and demographic scope of studies, improve analytical methods, and increase research funding and focus for wildland firefighters.

The …

Comparing Calcium, Vitamin D, And Calorie Intakes Among Unh Army Rotc Cadets With Low And Normal Bone Mineral Status, Ava Gaudette

Honors Theses and Capstones

No abstract provided.

Alpaca Assisted Activities In The New England Alpaca Industry: A Possible Solution To Farm Profitability And Participant Mental Health, Ashley Michele Masse

Honors Theses and Capstones

The high operating costs of the New England alpaca industry were putting the majority of alpaca farmers in this region in a state of financial loss. On a separate note, American communities were experiencing a prevalence of anxiety and depression. What if a single solution could help improve the outcome of both these challenges that seem to have little to do with each other? Alpaca Animal Assisted Activities (alpaca AAAs) was a possible solution. This study explored New England alpaca farm profitability and alpaca AAAs in a way no other research study has done before. A Farmer Survey was mailed …

Equine Rescue Success In The United States: A Statistical Analysis, Carly J. Cave

Honors Theses and Capstones

The high inflation that has characterized the post-pandemic period in the United States has increased the costs of horse ownership for private owners and equine rescue organizations, which are facing critical pressures. Over 200,000 equines are at risk for neglect or slaughter in the United States each year, which far exceeds the capacity to house these equines at rescue organizations. While demand on these organizations is high, their ability to afford appropriate resources for their care is insufficient. This study examined geographical and economic factors that impact equine rescues’ success in taking in at-risk equines and adopting them to forever …

Nursing Education And Comfort Level In Caring For Patients With Eating Disorders, Jaylyn E. Jewell

Honors Theses and Capstones

Nurses are integral to providing care to patients with eating disorders, who often present to the generalized hospital setting related to physical complications from their disorder. Despite the vital role nurses play, a lack of education is cited. This project sought to assess knowledge on eating disorders of nurses at a local hospital through dissemination of a survey. A total of n=18 responses were gathered. Results supported the fact that many nurses have received inadequate education on eating disorders, and consequently have low knowledge and competency in the care of these patients. This project seeks to identify this lack of …

Investigating The Relationship Between Politics And Education, Alaina M. Winrow

Honors Theses and Capstones

This paper looks into how politics plays a role in the public K-12 education system in the United States, specifically looking at the state of New Hampshire. Federal, state, and local governments provide important resources through funding to schools and create the laws that govern them. However, educational politics can be controversial at times. Within the past several years, there have been more tense school board meetings and divisive laws being passed or considered around the nation. Overall, the divisive political climate has influenced much of the discussion surrounding education and has created more stress for educators, administrators, school staff, …

Judging Our New Judges: Why We Must Remove Artificial Intelligence From Our Courtrooms Now, Kieran Duffy Newcomb

Honors Theses and Capstones

In this paper, I explore some of the ways in which artificial intelligence might enhance the sentencing process through recidivism prediction technology. Notably, this technology can increase the accuracy of risk predictions and the speed with which sentencing decisions are reached. I then show, however, that the recidivism prediction technology is likely to turn into what data scientist Cathy O’Neil calls a Weapon of Math Destruction. The potential harmfulness of this technology is due not to the inherent nature of the technology, but the symbiotic relationship it will have with our already harmful criminal justice system. I argue that the …

Evaluating Reactive Gliosis In The Brain Of Adult Zebrafish Following The Ingestion Of Nanopolystyrene., Hannah A. Kelehear

College of Graduate Studies: Theses & Dissertations

Polystyrene nanoplastics are one of the most pervasive environmental contaminants and have been shown to infiltrate multiple organ systems following ingestion. Studies in several animal models and humans have demonstrated that nanoplastics can cross the blood-brain barrier. Additionally, there is evidence that plastics will induce an inflammatory response in the brain involving reactive gliosis of microglia and astrocytes. This process has yet to be thoroughly investigated in the zebrafish model system in the context of micro-/nanoplastic ingestion. In the current study, we examined microglial and astrocytic phenotypes in the adult zebrafish telencephalon after consuming food contaminated with 44 nm polystyrene …

Development Of A Novel Measure To Assess For Alcohol Misuse In Older Adults: The Alcohol Misuse Scale For Older Adults (Amsoa), Nathan Jensen

College of Graduate Studies: Theses & Dissertations

Alcohol is the most regularly used intoxicating substance in most geographic locations. Alcohol use in the United States specifically is well over global averages. While alcohol misuse is generally considered to be understood as a problem for younger adults, it is often unrecognized and understudied older adult populations. Currently, there is an absence of a comprehensive tool measuring for developmentally salient behaviors, symptoms, and features of alcohol misuse in older adulthood, which blocks researchers’ ability to measure alcohol misuse well. The purpose of this study is to develop a psychometrically valid and reliable assessment of alcohol misuse for older adult …