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Articles 7381 - 7410 of 11726
Full-Text Articles in Entire DC Network
Bistro Mélange Business Plan, Cade Acosta
Flavors Of Change: Redefining Meat, Masculinity, And Mongolian, Khaliun Enkhbayar , '24
Flavors Of Change: Redefining Meat, Masculinity, And Mongolian, Khaliun Enkhbayar , '24
Senior Theses, Projects, and Awards
There is a saying among Mongolians that Mongolia was built on the four hoofs of livestock. Following this sentiment, Mongolians take pride in being raised on "meat and milk." My thesis explores the multifaceted role of meat in Mongolia, tracing its significance at the intersection of social connections, gender dynamics, and national identity against the backdrop of rapid socio-economic transformations over the past century.
In my research project, I followed a thread of changes that Mongolians have come to accept as their everyday reality. The past 100 years have been characterized by a widespread shift from a nomadic to a …
Ward 4 Asset Mapping Report, Molly Schnoke, Jack Yochum, Erika Shinn, Izzy Esler
Ward 4 Asset Mapping Report, Molly Schnoke, Jack Yochum, Erika Shinn, Izzy Esler
All Maxine Goodman Levin School of Urban Affairs Publications
The Center for Economic Development at the Levin College of Public Affairs and Education, Cleveland State University was contracted by Cleveland City Councilperson Deborah Gray to provide an accounting of assets and strengths in Cleveland’s Ward 4. The research team conducted interviews with stakeholders throughout the Ward, spoke to residents at community meetings, and conducted a survey of residents to better understand what challenges and opportunities residents and stakeholders felt were important for consideration in the planning of new projects and programs, support for existing services, and to provide guidance to the Councilperson for resource and funding considerations.
This work …
Implementation Of A Mental Health Consultation Program At An Early Childhood Education, Diana Buffington
Implementation Of A Mental Health Consultation Program At An Early Childhood Education, Diana Buffington
Master's Theses & Capstone Projects
Research shows that young children experiencing social emotional difficulties in early childhood can have a lasting impact on later functioning in school and through their adult lives. Additionally, research has suggested that mental health intervention in young children can significantly help children navigate these challenges. With these research findings in mind, this school improvement plan was created to deliver early childhood mental health consultation to an early childhood program serving at-risk children in the Bay Area of California. This plan is comprised of a prevention-oriented approach that strengthens the capacity of school staff to prevent, identify, treat, and reduce the …
Insecticide Susceptibilities And Enzyme Activities Of Four Stink Bug Populations In Mississippi, Usa, Yuzhe Du, Shane Scheibener, Yu Cheng Zhu, K. Clint Allen, Gadi V.P. Reddy
Insecticide Susceptibilities And Enzyme Activities Of Four Stink Bug Populations In Mississippi, Usa, Yuzhe Du, Shane Scheibener, Yu Cheng Zhu, K. Clint Allen, Gadi V.P. Reddy
Faculty Publications
In Mississippi, the Pentatomidae complex infesting soybean is primarily composed of Euschistus servus, Nezara viridula, Chinavia hilaris, and Piezodorus guildinii. This study employed spray bioassays to evaluate the susceptibilities of these stink bugs to seven commonly used formulated insecticides: oxamyl, acephate, bifenthrin, λ-cyhalothrin, imidacloprid, thiamethoxam, and sulfoxaflor. Stinks bugs were collected from soybeans in Leland, MS, USA during 2022 and 2023, as well as from wild host plants in Clarksdale, MS. There was no significant difference in the susceptibility of C. hilaris to seven insecticides between two years, whereas P. guildinii showed slightly increased susceptibility to neonicotinoids in 2023. Among …
Human Milk Components And The Infant Gut Microbiome At 6 Months: Understanding The Interconnected Relationship, Maryam Kebbe, Kartik Shankar, Leanne M. Redman, Aline Andres
Human Milk Components And The Infant Gut Microbiome At 6 Months: Understanding The Interconnected Relationship, Maryam Kebbe, Kartik Shankar, Leanne M. Redman, Aline Andres
Clinical Research Faculty Publications
Background: Human milk oligosaccharides have been shown to relate to the infant gut microbiome. However, the impact of other human milk components on infant gut bacterial colonization remains unexplored. Objectives: Our cross-sectional analysis aimed to investigate associations between human milk components (energy, macronutrients, free amino acids, inflammatory markers, and hormones) and infant gut microbiome diversity and composition (phylum, family, and genus) at 6 mo of age. Methods: Human milk and infant stool samples were collected at 6 mo postpartum. The infant gut microbiome was profiled using 16S rRNA sequencing. Linear regression models were performed to examine associations, adjusting for pregravid …
Validation Of Remote Child Weight And Height Measurements Within A Weight Management Trial, Alyssa M. Button, Amanda E. Staiano, Robbie A. Beyl, Richard I. Stein, Robert L. Newton, Alison Baker, Angela Lima, Jeanne Lindros, Anne Marie Conn, R. Robinson Welch, Stephen R. Cook, Denise E. Wilfley
Validation Of Remote Child Weight And Height Measurements Within A Weight Management Trial, Alyssa M. Button, Amanda E. Staiano, Robbie A. Beyl, Richard I. Stein, Robert L. Newton, Alison Baker, Angela Lima, Jeanne Lindros, Anne Marie Conn, R. Robinson Welch, Stephen R. Cook, Denise E. Wilfley
Population and Public Health Science Faculty Publications
Objective: The aim of this substudy within the Treatment Efforts Addressing Child Weight Management by Unifying Patients, Parents, and Providers (TEAM UP) pragmatic clinical trial was to compare the validity of anthropometric measurements collected remotely versus in person (≤7 days apart) among youth with obesity who were 6 to 15 years of age. Methods: Child (n = 37) weight and height were measured in person by a trained data assessor. These were compared with measurements taken remotely by the child's parent with live videoconferencing observation by a study data assessor. In-person and remote measurements were compared using Bland–Altman plots, Pearson …
Graduate Studies Newsletter (Spring 2024), Csusb - Office Graduate Studies
Graduate Studies Newsletter (Spring 2024), Csusb - Office Graduate Studies
Graduate Studies Newsletter
No abstract provided.
Time To Full Enteral Feeds In Hospitalised Preterm And Very Low Birth Weight Infants In Nigeria And Kenya, Zainab Imam, Helen Nabwera, Olukemi Tongo, Pauline Andang’O, Isa Abdulkadir, Chinyere Ezeaka, Beatrice Ezenwa, Iretiola Fajolu, Martha Mwangome, Dominic Umoru
Time To Full Enteral Feeds In Hospitalised Preterm And Very Low Birth Weight Infants In Nigeria And Kenya, Zainab Imam, Helen Nabwera, Olukemi Tongo, Pauline Andang’O, Isa Abdulkadir, Chinyere Ezeaka, Beatrice Ezenwa, Iretiola Fajolu, Martha Mwangome, Dominic Umoru
Paediatrics and Child Health, East Africa
Background: Preterm (born < 37 weeks’ gestation) and very low birthweight (VLBW; <1.5kg) infants are at the greatest risk of morbidity and mortality within the first 28 days of life. Establishing full enteral feeds is a vital aspect of their clinical care. Evidence predominantly from high income countries shows that early and rapid advancement of feeds is safe and reduces length of hospital stay and adverse health outcomes. However, there are limited data on feeding practices and factors that influence the attainment of full enteral feeds among these vulnera- ble infants in sub-Saharan Africa.
Aim: To identify factors that influence the time to full enteral feeds, defined as tolerance of 120ml/ kg/day, in hospitalised preterm and VLBW infants in neonatal units in two sub-Saharan Afri- can countries.
Methods: Demographic and clinical variables were collected for newborns admitted to 7 neonatal units in Nigeria and Kenya over 6-months. Multiple linear regression analysis was conducted to identify factors independently associated with time to full enteral feeds.
Results: Of the 2280 newborn infants admitted, 484 were preterm and VLBW. Overall, 222/484 (45.8%) infants died with over half of the deaths (136/222; 61.7%) occurring before …
Analyzing Pelvic Asymmetry By Sex And Ancestry: Insights From An Osteological Collection, Bryan O Ren, Robert W Goldberg, Karen D Standefer, Jason R Teplensky, Joseph P Drain, Conor F Mccarthy, John G Birch, Raymond W Liu
Analyzing Pelvic Asymmetry By Sex And Ancestry: Insights From An Osteological Collection, Bryan O Ren, Robert W Goldberg, Karen D Standefer, Jason R Teplensky, Joseph P Drain, Conor F Mccarthy, John G Birch, Raymond W Liu
Faculty, Staff and Student Publications
Introduction: Pelvic asymmetry has been noted in pelvic imaging, and might influence the development of various spinal pathologies, most notably scoliosis. There is a limited understanding of the relationship between pelvic asymmetry and sex and ancestry, and limited use of 3D modeling. The purpose of this study was to identify pelvic asymmetry and morphology differences between sex and ancestry utilizing 3D modeling on young adults in an osteological collection.
Methods: Thirty-three osteological pelvic specimens aged 18-25 years (average age 21.4 ± 2.0 years) were scanned to create virtual 3D models for analysis. Pelvic asymmetry and morphology were measured and compared …
Unl Emeriti And Retirees Association Newsletter, Spring 2024
Unl Emeriti And Retirees Association Newsletter, Spring 2024
UNL Emeriti and Retirees Association: Newsletters and Other Materials
University of Nebraska-Lincoln Emeriti and Retirees Association Newsletter, Spring 2024
Statin Therapy Vs. Plant-Based Diet For Reduction Of Plaque Burden In Coronary Artery Disease, Molly Evelyn Zak
Statin Therapy Vs. Plant-Based Diet For Reduction Of Plaque Burden In Coronary Artery Disease, Molly Evelyn Zak
Physician Assistant Scholarly Project Posters
Coronary artery disease is one of the most common chronic health conditions to affect adults in the United States, with heart disease being the leading cause of death. Contributing factors include high prevalence of processed foods containing saturated fats, low fiber diets and poor overall nutrition, and physical inactivity. These practices increase risk of low-density lipoprotein cholesterol (LDL-C) plaque buildup and calcification within arteries that supply the heart, leading to decreased blood flow and subsequent oxygen supply. Treatment for coronary artery disease has traditionally been dominated by HMG CoA-reductase inhibitors, or statins. These medications are more effective than the alternative …
Impact Of Pulsed Electric Field Treatment On Barley Germination For Malting, Rose Saxton, Caitlin Lahey, Brianna Smith, Emily Hibberd, Joshua Bevan, Cini Baumhoff, Ashley Galant, Jerry Young, Brian Meyer, Owen M. Mcdougal
Impact Of Pulsed Electric Field Treatment On Barley Germination For Malting, Rose Saxton, Caitlin Lahey, Brianna Smith, Emily Hibberd, Joshua Bevan, Cini Baumhoff, Ashley Galant, Jerry Young, Brian Meyer, Owen M. Mcdougal
Chemistry and Biochemistry Faculty Publications and Presentations
The malting process takes one week to steep, germinate, and kiln barley to make malt. Making quality malt is critically important to achieve the desired attributes of the finished beer, and the process is time-intensive and costly. Malt quality is assessed by indicators including β-glucan quantity, α-amylase activity, Free Amino Nitrogen (FAN) content, and overall extract concentration in the finished malt. Here, we report Pulsed Electric Field (PEF) treatment of barley to accelerate malt production. A small-scale trial of 250 g to 1.00 kg barley, was evaluated for germination at two PEF treatment conditions, generically referred to as “low” and …
Integration Of Art Tools In Calming Corners In Various Content Areas At The Secondary Level, Kathleen Petka
Integration Of Art Tools In Calming Corners In Various Content Areas At The Secondary Level, Kathleen Petka
Doctor of Education in Teacher Leadership Dissertations
This research study is a qualitative action research study that examines the best ways to support the emotional needs of students as they matriculate through high school. Specifically for this study, high school educators who teach in the four academic content areas (English, Math, Science, and Social Studies classes) implemented Calming Corners, an emotional support resource and intervention tool, in their classrooms. The teachers who participated in this study were able to assess if Calming Corners had a positive impact on students in their classrooms and in their own instructional practices. This study examined if the use of Calming Corners …
Unraveling The Impact Of Seed Fatty Acid Profiles On Spinach Seed Germination Under Temperature Stress, Mustafa Kaşka, Haluk Çağlar Kaymak
Unraveling The Impact Of Seed Fatty Acid Profiles On Spinach Seed Germination Under Temperature Stress, Mustafa Kaşka, Haluk Çağlar Kaymak
Turkish Journal of Agriculture and Forestry
Limited knowledge exists regarding the fatty acid profiles of spinach (Spinacia oleracea L.) seeds and their correlation with germination. This study aims to address this gap by thoroughly investigating these profiles and their relationship with seed germination. Therefore, the objectives include assessing how different temperatures influence seed germination in spinach cultivars, identifying tolerant cultivar(s) to temperature stress during germination, and exploring the relationship between fatty acid profiles and seed germination under varying temperature conditions. Nine spinach cultivars (‘Matador-1, 2, and 3’, ‘Ranchero F1’, ‘Aras F1’, ‘El Tajin’, ‘El Real’, ‘Catrina F1’ and ‘Poyraz F1’) were used as seed material. The …
Effect And Mechanisms Of Conifer And Broadleaf Mixtures On The Soil Characteristics In Limestone Mountains, Xueping Zhang, Yuhua Ma, Songling Fu, Jingjing Qian, Qi Zhu, Chun Feng, Zihao Li, Wenhao Zhu, Han Chen
Effect And Mechanisms Of Conifer And Broadleaf Mixtures On The Soil Characteristics In Limestone Mountains, Xueping Zhang, Yuhua Ma, Songling Fu, Jingjing Qian, Qi Zhu, Chun Feng, Zihao Li, Wenhao Zhu, Han Chen
Turkish Journal of Agriculture and Forestry
In the restoration process of limestone mountain ecosystem, the interaction mechanism, between vegetation and soil are the core scientific issues for a better understanding of ecological restoration and ecosystem stability. Based on this, four types of 30 year old artificial forest communities with different coniferous and broad-leaved mixed ratios (0-20 %, 20 - 50 %, 50 – 80 %, 80 – 100 %) in typical limestone mountainous areas of the northern subtropical region are used as research objects to measure understory vegetation diversity, litter, and fine root characteristics. The impact of different mixing ratios on understory vegetation restoration and soil …
Comparison Of Perceived Stress In First-Year Pre-Med Students And First-Year Medical Students At Usd, Maggie Derner
Comparison Of Perceived Stress In First-Year Pre-Med Students And First-Year Medical Students At Usd, Maggie Derner
Honors Thesis
Stress can be caused by many factors, including money, relationships, promotions, grades, and responsibilities. In college, these stressors can be exacerbated. This research dives into stress in both undergraduate students as well as medical students. Previous literature has indicated that high levels of stress are present in students, and it is likely to have negative effects on the students, whether that is their mental or physical well-being. Schools have put interventions in place to help combat the stress levels present in their students. At the University of South Dakota (USD) and USD Sanford School of Medicine (USD SSOM), perceived stress …
Bridging The Gap: Strategies For Enhancing Wic Participation Rates In South Dakota, Melissa K. Wyum
Bridging The Gap: Strategies For Enhancing Wic Participation Rates In South Dakota, Melissa K. Wyum
Honors Thesis
The Special Supplemental Nutrition Program for Women, Infants, and Children (WIC) is a national program administered by the USDA to State agencies for low-income women and nutritionally at-risk infants and children. South Dakota WIC provides services related to breastfeeding, healthcare referrals, and accessibility/knowledge of nutritious foods. Successes of WIC include improved birth outcomes, decreased healthcare costs, regular immunization rates, establishment of a primary care provider, and improved nutrition status. Although WIC has shown positive health outcomes for mothers and children, the relationship between the barriers of WIC access and resulting health outcomes in South Dakota is unknown. According to the …
The Relationship Of Anterior Malocclusion With Phoneme Articulation In Children Aged 6-12 Years In Makassar, Indonesia, Karima Q. Mansjur, Baharuddin M. Ranggang, Mansjur Nasir, Susilowati Mudjari, Bella A. Satria, Eka Savitri
The Relationship Of Anterior Malocclusion With Phoneme Articulation In Children Aged 6-12 Years In Makassar, Indonesia, Karima Q. Mansjur, Baharuddin M. Ranggang, Mansjur Nasir, Susilowati Mudjari, Bella A. Satria, Eka Savitri
Journal of Dentomaxillofacial Science
Objective: This study aims to establish the correlation between anterior malocclusion and phoneme articulation among children between 6 and 12 years old in Makassar, Indonesia.
Material and methods: A cross-sectional study was conducted on 157 elementary school students aged 6-12 in Makassar City, Indonesia. The sampling method used was purposive to identify students who met specific inclusion and exclusion criteria. Each student underwent an examination to determine the presence of anterior dental malocclusion and articulation check using a multi-word format consisting of phonemes. The data was analyzed using SPSS version 27.
Result: The statistical tests conducted using the Chi-Square method …
Description Of Eruption Of Permanent Upper Canine Teeth In Stunting Children At Koto Balingka West Pasaman Elementary School, Intan Be. Mahata, Sri P. Utami, Athifa Trisa
Description Of Eruption Of Permanent Upper Canine Teeth In Stunting Children At Koto Balingka West Pasaman Elementary School, Intan Be. Mahata, Sri P. Utami, Athifa Trisa
Journal of Dentomaxillofacial Science
Objective: The aim of this study was to describe the eruption of the permanent upper canine teeth in stunted children at Koto Balingka Elementary School, West Pasaman.
Materials and methods: This research is a quantitative descriptive observational study with a case control design. The sampling technique is purposive sampling. The number of samples in this study was 60 children consisting of 30 (50%) stunted children and 30 (50%) normal children aged 11-12 years in the Parit Koto Balingka Health Center Working Area. Univariate analysis is presented in the form of frequency distribution and percentages.
Results: Research shows that 20 (66.7%) …
2023 Nursing Annual Report, Children's Health System Of Texas
2023 Nursing Annual Report, Children's Health System Of Texas
2023
No abstract provided.
Empty Coolers At Busy Dining Halls: Solutions To Gvsu’S Failure To Accommodate Students With Food Allergies, Elena Chiu
Empty Coolers At Busy Dining Halls: Solutions To Gvsu’S Failure To Accommodate Students With Food Allergies, Elena Chiu
Honors Projects
GVSU is failing its students with food allergies by not providing the proper accommodations in Campus Dining facilities. This paper provides the experience of two students with food allergies' struggle to eat at GVSU, then takes a brief look into the Americans with Disabilities Act to show the issues and why they need to be fixed. This is followed by a comparison of GVSU's dining program and the highest ranked food allergy safety university, MSU. Using MSU's program as a framework, multiple solutions, such as creating stable meal options and displaying ingredients online, are provided to create a Campus Dining …
The Significance Of Palliative Care Education And Areas For Improvement, Lindsey Bunday
The Significance Of Palliative Care Education And Areas For Improvement, Lindsey Bunday
Honors Projects
Palliative care is vital in prioritizing quality of life for patients with serious illnesses. Such care is crucial to help patients understand their prognosis, address needs, and meet goals of care. However, physician shortages, improper utilization, and non-standardized medical curriculum amplify the gaps in care and demonstrate significant room for improvement. Innovative curriculum and opportunities for knowledge advancement can refine education and improve patient care.
Accommodations And Resources For Audiologists With Hearing Loss, Joseph Thomas Kraus
Accommodations And Resources For Audiologists With Hearing Loss, Joseph Thomas Kraus
Doctoral Scholarly Projects & Capstones
Hearing loss affects millions of people worldwide. The audiology profession strives to help all individuals achieve their communicative goals and needs, providing support and expertise to a deserving population. Audiologists themselves are not immune to the challenges of hearing differences themselves. This project has two main objectives to identify and discuss needs and challenges faced by audiologists, both within their professional field, as well as their educational upbringing, and to highlight specific accommodations that can enhance their professional success. The research phase of this project aims to develop a resource guide tailored to the needs of audiologists with hearing loss …
Consideration For Expanding The Audiology Scope Of Practice To Include Prescription Medication Authority, Erin Grace Gill
Consideration For Expanding The Audiology Scope Of Practice To Include Prescription Medication Authority, Erin Grace Gill
Doctoral Scholarly Projects & Capstones
The demand for medical professionals rises in conjunction with the rise of prescriptions written annually in the United States, but there are not enough physicians to meet the demand for patient prescriptions (Mohamadloo et al., 2019). In the United States, 2.4 million healthcare visits for acute otitis externa were recorded in 2007; approximately half were between the ages of 5-14 years old. Healthcare providers were estimated to have spent about 600,000 hours treating acute otitis externa.
Prescriptive authority is the ability of healthcare providers to prescribe specific medications, including controlled substances. Prescriptive authority is legally allocated by federal and state …
Exploring The Intestinal Microbial Community Of Lantang Pigs Through Metagenome-Assembled Genomes And Carbohydrate Degradation Genes, Jianbo Yang, Ying Fan, Rui Jin, Yunjuan Peng, Jianmin Chai, Xiaoyuan Wei, Yunxiang Zhao, Feilong Deng, Jiangchao Zhao, Ying Li
Exploring The Intestinal Microbial Community Of Lantang Pigs Through Metagenome-Assembled Genomes And Carbohydrate Degradation Genes, Jianbo Yang, Ying Fan, Rui Jin, Yunjuan Peng, Jianmin Chai, Xiaoyuan Wei, Yunxiang Zhao, Feilong Deng, Jiangchao Zhao, Ying Li
Animal Science Faculty Publications and Presentations
High-fiber, low-cost agricultural byproducts offer a sustainable alternative for mitigating the competition for crops between humans and livestock. Pigs predominantly utilize dietary fibers through the process of microbial fermentation within the gut. This study explored the gut microbiota and the capacity for carbohydrate degradation in 30 individual Lantang pigs, a breed indigenous to China. Through metagenomic analysis, a total of 671 metagenome-assembled genomes (MAGs) were assembled and assigned into 14 bacterial and 1 archaeal phylum, including 97 species from uncultured microbes. The phylum with the highest abundance were identified as Bacillota_A, Bacteroidota, and Bacillota. Remarkably, the investigation revealed nearly 10,000 …
Columns Spring 2024, Southern Adventist University
Columns Spring 2024, Southern Adventist University
Alumni Newsletter
Features information about the School of Nursing, Ukrainian aid, and other campus events.
Improving Self-Care Knowledge: A Nurse-Led Multimedia Patient Teaching Initiative For Hospitalized Patients With Heart Failure, Christine S. Boehm Jd, Bsn,Rn
Improving Self-Care Knowledge: A Nurse-Led Multimedia Patient Teaching Initiative For Hospitalized Patients With Heart Failure, Christine S. Boehm Jd, Bsn,Rn
Doctor of Nursing Practice Projects
Background: Patients must perform self-care after discharge to manage their heart failure. In the project setting, usual care includes a handout for patients with or without verbal teaching. Multimedia education gives patients the ability to learn with a combination of methods - video, verbal and written.
Objective: The purpose of this quality improvement project was to determine if patients with heart failure have a greater increase in self-care knowledge before discharge with the use of multimedia patient education consisting of video, verbal teaching and written materials, compared to the usual care of verbal teaching and written materials.
Methods: This project …
The Dmptool Nih Dmsp Templates Project, Nina Exner, Seonyoung Kim, Katy Smith
The Dmptool Nih Dmsp Templates Project, Nina Exner, Seonyoung Kim, Katy Smith
2020-Current year OA Pubs
The DMPTool NIH Data Management and Sharing Plan (DMSP) Templates Project was launched in response to the 2023 NIH Data Management and Sharing (DMS) Policy. This new policy introduced a more structured framework for DMS Plans, featuring six key elements, a departure from the 2003 NIH DMS policy. The project aimed to simplify the process for data librarians, research administrators, and researchers by providing a template with curated guidance, eliminating the need to navigate various policies and guidelines. The template breaks out each Plan section and subsection and provides related guidance and examples at the point of need. This effort …
Prevotella Copri And Microbiota Members Mediate The Beneficial Effects Of A Therapeutic Food For Malnutrition, Hao-Wei Chang, Evan M Lee, Yi Wang, Cyrus Zhou, Kali M Pruss, Suzanne Henrissat, Robert Y Chen, Clara Kao, Matthew C Hibberd, Hannah M Lynn, Daniel M Webber, Marie Crane, Jiye Cheng, Ye Chen, Jeffrey I Gordon, Et Al.
Prevotella Copri And Microbiota Members Mediate The Beneficial Effects Of A Therapeutic Food For Malnutrition, Hao-Wei Chang, Evan M Lee, Yi Wang, Cyrus Zhou, Kali M Pruss, Suzanne Henrissat, Robert Y Chen, Clara Kao, Matthew C Hibberd, Hannah M Lynn, Daniel M Webber, Marie Crane, Jiye Cheng, Ye Chen, Jeffrey I Gordon, Et Al.
2020-Current year OA Pubs
Microbiota-directed complementary food (MDCF) formulations have been designed to repair the gut communities of malnourished children. A randomized controlled trial demonstrated that one formulation, MDCF-2, improved weight gain in malnourished Bangladeshi children compared to a more calorically dense standard nutritional intervention. Metagenome-assembled genomes from study participants revealed a correlation between ponderal growth and expression of MDCF-2 glycan utilization pathways by Prevotella copri strains. To test this correlation, here we use gnotobiotic mice colonized with defined consortia of age- and ponderal growth-associated gut bacterial strains, with or without P. copri isolates closely matching the metagenome-assembled genomes. Combining gut metagenomics and metatranscriptomics …