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Internal Culture, External Impact: How A Changemaking Culture Positions Foundations To Achieve Transformational Change – With 2024 Prologue, Amy Celep, Sara Brenner, Rachel Mosher-Williams

The Foundation Review

Editor’s Note: This article, first published in print and online in 2016, has been republished by The Foundation Review with minor updates.

This article argues that a foundation’s internal culture is critical to achieving large-scale social change, but that efforts to build a changemaking culture too often are left out of strategy conversations.

While there is no one culture that suits every foundation, a particular set of characteristics must be present in those that seek largescale social change: a focus on outcomes, transparency, authenticity, collaboration, racial equity and inclusion, continuous learning, and openness to risk.

This article offers insights into …

June 2024, Swosu Bulldog Wellness Committee

SWOSU BULLDOG WELLNESS

June is Alzheimer’s and Brain Awareness Month

Alzheimer’s and Brain Awareness Month is a time to share facts about Alzheimer’s disease and other dementias that affect the brain.

A Quantitative Analysis Of University Counselors And Student Affairs Personnel's Knowledge And Confidence In Working With Students With Autism Spectrum, Sandra Araiza Salazar

Dissertations

University counselors and student affairs personnel often find themselves unprepared to address the needs of undergraduate students with autism spectrum disorder. Many of these professionals are not receiving the proper training or education to prepare for the unique social, emotional, and academic needs of these neurodiverse students. Due to this trend, many university counselors and student affairs personnel may lack the necessary knowledge and confidence in serving this neurodiverse population. In this first-of-its-kind study, university counselors and student affairs personnel’s knowledge and confidence in working with undergraduate students with autism spectrum was analyzed. A nonrandom sample of university counselors and …

Titration Of Dietary Histidine During A 22-To 42-Day Feeding Phase Following A 0-To 21-Day Feeding Phase With Variable Dietary Histidine Concentrations In Female Cobb 500 Broilers, Kenneth B. Nelson, Matheus F. Costa, Savannah C. Wells-Crofton, Shivaram K. Rao, Garrett J. Mullenix, Craig W. Maynard, Michael T. Kidd

Poultry Science Faculty Publications and Presentations

Further reductions of crude protein in broiler diets may cause essential amino acids traditionally considered to be supplied at adequate levels to become limiting. Requirement data for histidine are currently scarce and this amino acid is uniquely able to be stored within the body. Thus, the objectives of this study were to evaluate female Cobb 500 broiler growth performance and carcass characteristic responsiveness to increasing digestible histidine to digestible lysine ratios (dHis:dLys) during a 22- to 42-day feeding period and determine if dHis:dLys in preceding feeds influence the former responses. Starter diets were formulated to contain dHis:dLys of 33% or …

Association Of Knowledge And Health Habits With Physiological Hydration Status, Brendon P. Mcdermott, Xiujing Zhao, Jennifer C. Veilleux

Poultry Science Faculty Publications and Presentations

The association of hydration knowledge and health habits with hydration status and fluid intake is rarely examined. We sought to determine whether knowledge or physical health behaviors predict physiological hydration status and fluid intake. Ninety-six participants (59 female; 27 ± 10 year) completed the previously validated hydration survey. Participants then recorded total fluids consumed (TFC), collected urine, and tracked void frequency for 24 h. Hydration status was assessed via 24 h urine specific gravity (USG) and osmolality (U_osm). Health behaviors included self-reported physical activity, BMI, smoking, alcoholic drinking, and sleep status. TFC was significantly correlated with 24 h …

Assessing The Impact Of Spirulina Platensis And Organic Trace Minerals On The Incidence Of Bacterial Chondronecrosis With Osteomyelitis Lameness In Broilers Using An Aerosol Transmission Model, Andi Asnayanti, Amer Hasan, Khawla Alharbi, Intisar Abdullah Hassan, Walter Bottje, Samuel J. Rochell, Marco A. Rebollo, Michael T. Kidd, Adnan A.K. Alrubaye

Poultry Science Faculty Publications and Presentations

Spirulina platensis is an emerging poultry diet source due to its essential nutrition and bioactive ingredients. Spirulina microalgae confers beneficial effects on broiler's growth performance, immune response, and antioxidant activity. We investigated the effect of Spirulina platensis on BCO lameness, one of the most driving factors for economic and animal well-being concerns in the poultry industry. Additionally, supplementation of Availa ZMC containing organic trace minerals – zinc, manganese, and copper – was shown to alleviate lameness by 20 to 25%. We hypothesized that pairing microalgae and organic trace minerals might confer a synergistic effect in reducing BCO. A 2 × …

Preparing Patients For Oral Immunotherapy (Ppoint): International Delphi Consensus For Procedural Preparation And Consent, Richard L Wasserman, Mariam A Hanna, Marcus Shaker, Mimi L K Tang, Pablo Rodríguez Del Río, Brad Sobolewski, Elissa M Abrams, Aikaterini Anagnostou, Stefania Arasi, Sakina Bajowala, Philippe Bégin, Scott B Cameron, Edmond S Chan, Sharon Chinthrajah, Andrew T Clark, Paul Detjen, George Du Toit, Motohiro Ebisawa, Arnon Elizur, Jeffrey M Factor, Justin Greiwe, Jonathan O'B Hourihane, Sarah W Hughes, Douglas H Jones, Antonella Muraro, Anna Nowak-Wegrzyn, Nandinee B Patel, Amy M Scurlock, Atul N Shah, Sayantani B Sindher, Stephen Tilles, Brian P Vickery, Julie Wang, Hugh H Windom, Matthew Greenhawt

Faculty, Staff and Students Publications

BACKGROUND: Despite the promise of oral immunotherapy (OIT) to treat food allergies, this procedure is associated with potential risk. There is no current agreement about what elements should be included in the preparatory or consent process.

OBJECTIVE: We developed consensus recommendations about the OIT process considerations and patient-specific factors that should be addressed before initiating OIT and developed a consensus OIT consent process and information form.

METHODS: We convened a 36-member Preparing Patients for Oral Immunotherapy (PPOINT) panel of allergy experts to develop a consensus OIT patient preparation, informed consent process, and framework form. Consensus for themes and statements was …

Predicting Mortality Within 1 Year Of Art Initiation In Children And Adolescents Living With Hiv In Sub-Saharan Africa: A Retrospective Observational Cohort Study, Abigail Seeger, Phumzile Dlamini, Sandile Ndabezitha, Nobuhle Mthethwa, Teresa Steffy, Lilian Komba, Pauline Amuge, Eunice Ketangenyi, Peter Elyanu, Adamson Munthali, Amos Msekandiana, Yvonne Maldonado, Elizabeth Chiao, Adeodata Kekitiinwa, Lineo Thahane, Lumumba Mwita, H Lester Kirchner, Anna Maria Mandalakas

Faculty, Staff and Students Publications

BACKGROUND: Differentiated service delivery (DSD) for children and adolescents living with HIV can improve targeted resource use. We derived a mortality prediction score to guide clinical decision making for children and adolescents living with HIV.

METHODS: Data for this retrospective observational cohort study were evaluated for all children and adolescents living with HIV and initiating antiretroviral therapy (ART); aged 0-19 years; and enrolled at Baylor clinics in Eswatini, Malawi, Lesotho, Tanzania, and Uganda between 2005 and 2020. Data for clinical prediction, including anthropometric values, physical examination, ART, WHO stage, and laboratory tests were captured at ART initiation. Backward stepwise variable …

Specific Gravity Improves Identification Of Clinically Significant Quantitative Proteinuria From The Dipstick Urinalysis, Song Zhang, Michael Li, Ella Carroll, Vaishnavi Kannan, Duwayne L Willett, S Susan Hedayati

Faculty, Staff and Students Publications

KEY POINTS: Urine albumin-to-creatinine ratio and urine protein-to-creatinine ratio are frequently obtained and represent possible tools for screening for proteinuria and thus early CKD. Adding specific gravity to dipstick proteinuria improves the ability to screen patients with clinically significant proteinuria and can be used to identify patients with early CKD.

BACKGROUND: CKD is often underdiagnosed during early stages when GFR is preserved because of underutilization of testing for quantitative urine albumin-to-creatinine ratio (UACR) or urine protein-to-creatinine ratio (UPCR). Semiquantitative dipstick proteinuria (DSP) on urinalysis is widely obtained but not accurate for identifying clinically significant proteinuria.

METHODS: We identified all patients …

Genetic Evaluation For Monogenic Disorders Of Low Bone Mass And Increased Bone Fragility: What Clinicians Need To Know

Faculty, Staff and Students Publications

Purpose of review: The purpose of this review is to outline the principles of clinical genetic testing and to provide practical guidance to clinicians in navigating genetic testing for patients with suspected monogenic forms of osteoporosis.

Recent findings: Heritability assessments and genome-wide association studies have clearly shown the significant contributions of genetic variations to the pathogenesis of osteoporosis. Currently, over 50 monogenic disorders that present primarily with low bone mass and increased risk of fractures have been described. The widespread availability of clinical genetic testing offers a valuable opportunity to correctly diagnose individuals with monogenic forms of osteoporosis, thus instituting …

Racial And Ethnic Disparities In Cardiovascular Disease – Analysis Across Major Us National Databases, Heather M Johnson, Steve Antoine, Fatima Rodriguez, Marat Fudim, Erin D Michos, Arunima Misra, Layla Abushamat, Vijay Nambi, Gregg C Fonarow, Christie M Ballantyne, Salim S Virani

Faculty, Staff and Students Publications

Background: There are several studies that have analyzed disparities in cardiovascular disease (CVD) health using a variety of different administrative databases; however, a unified analysis of major databases does not exist. In this analysis of multiple publicly available datasets, we sought to examine racial and ethnic disparities in different aspects of CVD, CVD-related risk factors, CVD-related morbidity and mortality, and CVD trainee representation in the US.

Methods: We used National Health and Nutrition Examination Survey, National Ambulatory Medical Care Survey, National Inpatient Sample, Centers for Disease Control and Prevention Wide-Ranging OnLine Data for Epidemiologic Research, United Network for Organ Sharing, …

Long-Term Sustained Effects Of The Look Ahead Lifestyle Intervention On Body Composition Among Adults With Type 2 Diabetes, Henry Pownall, Blandine Laferrère, Ashok Balasubramanyam, Steven B Heymsfield, Thomas A Wadden, Dympna Gallagher

Faculty, Staff and Students Publications

Objective: The objective of the study was to test whether there are sustained effects of the Look AHEAD intensive lifestyle intervention (ILI), versus diabetes support and education (DSE), on weight and body composition 12 to 16 years after randomization.

Methods: Participants were a subset of enrollees in the Look AHEAD dual-energy x-ray absorptiometry substudy who completed the final visit, composed of men (DSE = 99; ILI = 94) and women (DSE = 134; ILI = 135) with type 2 diabetes and mean (SD) age 57.2 (6.4) years and BMI 34.9 (5.1) kg/m2 at randomization. Dual-energy x-ray absorptiometry measured total and …

Anoctamin 4 Defines Glucose-Inhibited Neurons In The Ventromedial Hypothalamus

Faculty, Staff and Students Publications

No abstract provided.

Associations Of Testosterone And Related Hormones With All-Cause And Cardiovascular Mortality And Incident Cardiovascular Disease In Men : Individual Participant Data Meta-Analyses, Robert J Adams, Leen Antonio, Christie M Ballantyne, Douglas C Bauer, Shalender Bhasin, Mary L Biggs, Peggy M Cawthon, David J Couper, Adrian S Dobs, Leon Flicker, David J Handelsman, Graeme J Hankey, Anke Hannemann, Robin Haring, Benjumin Hsu, Sean A Martin, Alvin M Matsumoto, Dan Mellström, Claes Ohlsson, Terence W O'Neill, Eric S Orwoll, Matteo Quartagno, Molly M Shores, Antje Steveling, Åsa Tivesten, Thomas G Travison, Dirk Vanderschueren, Gary A Wittert, Frederick C W Wu, Kevin Murray

Faculty, Staff and Students Publications

Background: Whether circulating sex hormones modulate mortality and cardiovascular disease (CVD) risk in aging men is controversial.

Purpose: To clarify associations of sex hormones with these outcomes.

Data sources: Systematic literature review to July 2019, with bridge searches to March 2024.

Study selection: Prospective cohort studies of community-dwelling men with sex steroids measured using mass spectrometry and at least 5 years of follow-up.

Data extraction: Independent variables were testosterone, sex hormone-binding globulin (SHBG), luteinizing hormone (LH), dihydrotestosterone (DHT), and estradiol concentrations. Primary outcomes were all-cause mortality, CVD death, and incident CVD events. Covariates included age, body mass index, marital status, …

Continuous Renal Replacement Therapy: Current State And Future Directions For Worldwide Practice, Taiki Haga, Demet Demirkol, Michael J Bell, Ayse Akcan-Arikan

Faculty, Staff and Students Publications

No abstract provided.

Developing A Computational Representation Of Human Physical Activity And Exercise Using Open Ontology-Based Approach: A Tai Chi Use Case, Muhammad Tuan Amith

Faculty, Staff and Student Publications

Many studies have examined the impact of exercise and other physical activities in influencing the health outcomes of individuals. These physical activities entail an intricate sequence and series of physical anatomy, physiological movement, movement of the anatomy, etc. To better understand how these components interact with one another and their downstream impact on health outcomes, there needs to be an information model that conceptualizes all entities involved. In this study, we introduced our early development of an ontology model to computationally describe human physical activities and the various entities that compose each activity. We developed an open-sourced biomedical ontology called …

Water Management And Conservation In India Fostering Water Justice: Arguing For Adopting Just Sustainability In Water Governance, Gayathri D Naik Dr, Sanjay Shenoi P

Articles

The water sector is characterised by everyday water injustices where factors like social discrimination, economic disparities, and political preferences influence the determination of water resource access, allocation, and management. The increasing anthropogenic impacts on water resources and consequent threats to sustainability add to the water injustices, often impacting the poorer, socially downtrodden communities that bear the brunt of water scarcity and cannot afford alternatives. The current water governance patterns, prioritising equality over equity, fail to address the issues of water injustices created by social, political, and economic factors in water management and sideline the ecological impacts on water resources. Moving …

Ecotoxicological Impacts Of Landfill Sites: Towards Risk Assessment, Mitigation Policies And The Role Of Artificial Intelligence, Krishna Gautam, Namrata Pandey, Dhvani Yadav, Ramakrishnan Parthasarathi, Andrew Turner, Sadasivam Anbumani, Awadhesh N. Jha

School of Geography, Earth and Environmental Sciences

Waste disposal in landfills remains a global concern. Despite technological developments, landfill leachate poses a hazard to ecosystems and human health since it acts as a secondary reservoir for legacy and emerging pollutants. This study provides a systematic and scientometric review of the nature and toxicity of pollutants generated by landfills and means of assessing their potential risks. Regarding human health, unregulated waste disposal and pathogens in leachate are the leading causes of diseases reported in local populations. Both in vitro and in vivo approaches have been employed in the ecotoxicological risk assessment of landfill leachate, with model organisms ranging …

Occurrence Of Lotmaria Passim In Africanized And European Honey Bee, Apis Mellifera, Lineages From The United States, Mary-Kate Williams, Dylan Cleary, Allen Szalanski

Entomology and Plant Pathology Faculty Publications and Presentations

Honey bee populations in the United States have been under stress for the past several decades. Several internal parasites may contribute to this, including the trypanosome Lotmaria passim. It is unknown how widespread the honey bee parasite, L. passim, is in Africanized honey bee (AHB) populations in the United States. A total of 321 feral honey bee colony samples which had been previously recorded to be of Africanized origin using molecular diagnostics from California (n=3), New Mexico (n=46), Oklahoma (n=57), Texas (n=106), and Utah (n=109) were used in this study. Of these samples, a total of 15 (4.7%) …

Functional Characterization Of Potato Arp1 Gene Encoding Auxin-Repressed Protein, Sara Ali Alneyadi

Theses

Auxin-repressed proteins (ARPs) are conserved in higher plants and are involved in plant growth and development by controlling gene expression. ARP1 has been studied for its role in biotic stress response, but its role in abiotic stress response remains unclear. In this study, transgenic Arabidopsis plants expressing potato (S. tuberosum) ARP1 were evaluated for their salinity stress response. By gradually increasing NaCl concentrations from 0 to 200mM, plants were subjected to high salinity stress. As compared to wild-type (WT) control plants under stressed conditions, the ARP1 transgenic plants demonstrated improved height and root length and higher chlorophyll content. Under …

Characteristics Of Lactobacillus Helveticus Fermentation Of Camel And Bovine Milks, Kobika Chelladhurai

Theses

In this study, the fermentation of low-fat camel milk (CM) and bovine milk (BM) with Lactobacillus helveticus was compared to fermentation with L. delbrueckii subsp. bulgaricus, and S. thermophilus at 28°C, 35°C, and 42°C. The fermentation activities were followed by measuring bacterial counts, titratable acidity, pH, and changes in lactose, organic acids, and proteolysis for 96 hours. Although bacterial growth was comparable in CM and BM, the fermented milks showed differences in acidification and proteolysis. Negative correlations between TA (%) and pH were consistent in both CM and BM suggesting similar buffering capacities. In both milks, L. helveticus …

Salivary Microbiome Signature In Pediatric Inflammatory Bowel Disease, Ghaidaa Mohammed Mesto

Theses

Inflammatory bowel disease (IBD) is a complex disorder characterized by chronic inflammation of the gastrointestinal tract (GIT). IBD mainly includes two distinct diseases, namely Crohn’s disease (CD) and ulcerative colitis (UC). To date, the precise etiology of these conditions is not fully elucidated, although a strong relationship between microbial dysbiosis in the GIT and IBD has been proposed. In general, limited data is available on the oral microbiome of IBD patients, despite its recognizable role in impacting gut health. There is a paucity of research on IBD in the pediatric population, although this disease is becoming more prevalent than in …

Physicochemical Properties Of Edible Cricket Oils: Implications For Use In Pharmaceutical And Food Industries, Dorothy K. Murugu, Arnold N. Onyango, Alex K. Ndiritu, Dorothy N. Nyangena, Isaac M. Osuga, Xavier Cheseto, Sevgan Subramanian, Sunday Ekesi, Chrysantus M. Tanga

All Peer-Reviewed Publications

The prevailing global market demands locally produced, sustainable oils for biomedical applications. This study focused on evaluating the quality of cricket-derived oils and meals from Scapsipedus icipe Hugel, Tanga, and Gryllus bimaculatus De Geer common delicacy in Africa, following standard methods for physicochemical properties, fatty acid composition, and phytochemicals (oxalates, phytates, tannins, and polyphenols). The cricket oils physicochemical properties aligned with Codex Alimentarius standards for edible oils, including low solidification temperature (< 2 °C), a high refractive index (1.46), and a specific gravity of 0.88. Notably, peroxide values (1.9 to 2.5 mg mEq O2/kg), acid values (1.1 to 2.2 mg KOH/g), and saponification values (234–246 mg KOH/g) all are indicative of lightness and unsaturated fatty acids. Nutritionally, cricket powder was rich in protein (56.8–56.9% -) and fat (31.7–33.5% -of dry matter), with significant amounts of essential omega-3 and omega-6 fatty acids. Predominant saturated and monounsaturated fatty acids were palmitic (23.9–31.2 mg/100 g-) and oleic acids (10.9–11.4 mg/100 g- of oil), respectively. Antioxidant values (48.0 to 65.0 mg/100 g), inferred from total polyphenols, suggests a stable oil with long shelf-life. These results highlight the promising and sustainable potential of cricket-derived oils for applications in the food and pharmaceutical industries.

Isolation And Molecular Characterization Of Acanthamoeba Spp. From Iraqi Patients With Keratitis, Muna B. Aldin, Naksheen M. Ardalan, Khudair Abbas Jassim

Baghdad Science Journal

Isolation and molecular characterization of Acanthamoeba spp. related corneal infections in Iraqi Patients. A total of 96 samples from corneal scraps and contact lenses were gathered from corneal patients for the current trial, which runs from November 2020 to May 2021. All plates were checked, classifying them as positive or negative morphologically identification of Acanthamoeba spp. where PCR analysis, which entails the targeted amplification of nucleic acids, has been carried out, and where The 18s rRNA gene's DF3 region was the focus of the isolated strains' sequences. Three patients had Acanthamoeba spp. infections, according to the findings. then the sequence …

Burnout In Healthcare, Katie Bernard Rn Bsn, Kiana Fuller Rn Adn, Ashley Rhoades Rn Bsn

Nurse Residency

In a hospital setting, are nurses who practice coping strategies at a lower risk for nurse burnout then nurses who do not?

Reduction Of Skin Breakdown With Early Indication Of Low Braden Scale Score, Robert Inniss Rn, Bsn, Kendra Sloan

Nurse Residency

In adult patients being admitted to the hospital from the emergency department, will early indication of low Braden Scale scores and the use of an air mattress help prevent skin integrity breakdown/help prevent the further breakdown of skin in patients who already are experiencing skin breakdown?

Who Calls For Action To Uphold Right To Health Amidst Inaction, Injustice And Crises

Saudi Medical Journal

No abstract provided.

Evaluation Of Candidemia Risk Factors And Candida Species Distribution In Intensive Care Units Among Patients With And Without Covid-19, Cemile Uyar, Emel Yıldız, Özlem Genç, Öznur Ak, Emel Koçak, Sevil Alkan, Canan Balcı, Pınar Korkmaz, Duru Mıstanoğlu Özatağ, Halil Aslan

Saudi Medical Journal

Objectives: To assess the risk variables related to the types of candidemia for each patient, who was admitted into the intensive care unit regardless of the patient with or without complete diagnosis of COVID-19, during the period of March 2019 to December 2022. Methods: The evaluation comparison of demographic and clinical data of COVID-19 positive and negative patients with candidemia confirmed in blood, 113 cases were assessed. Variables such as gender, age, age of hospitalization, history of hospitalization, concurrently infection, The acute physiology and chronic health evaluation-II scores, comorbidity checking, intubation, central venous catheter use, parenteral nutrition use, steroid use, …

Digital Transformation: Two Sides Of A Coin, Tze K Koh

Research Collection College of Integrative Studies

It is of paramount importance to examine the intersection of digital transformation and sustainability. At the same time, there is a growing imbalance between digitalisation within the workforce and the pace at which sustainability awareness is picking up. Addressing this gap is crucial.

A Review Of A Ketogenic Diet In The Treatment Of Autism Spectrum Disorder, Eugene Reznik

Loma Linda University Electronic Theses, Dissertations & Projects

Autism Spectrum Disorder effects millions of people every year, however pharmacological and behavioral treatments remain limited. The need for adjunctive therapies such as diet invervention [sic] that target autism spectrum disorder symptoms Is [sic] needed now more than ever. A connection between a ketogenic diet, which is high in fat and low in carbohydrates, and autism spectrum disorder can be made as the diet has shown potential in ameleriotating [sic] common comorbidities within the autism spectrum disorder population such as metabolic dysfunction, gut-microbiome dysfunction, medication resistant epilepsy, and various psychiatric disorders. Hence, this review focuses on the results and methods …