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Efficacy Of Vitamin D Supplementation On Hepcidin/Ferroportin Axis And Vdr Expression In Hfhf-Fed Rats, Hager Mosaad Saad Abd-Elgwaad, Heba Adel Abd El-Hamid Barakat, Eman Hassan Abdel Aziz Sharaf, Nourhan Gamal El-Rahmany

Baghdad Science Journal

Targeting the hepcidin-ferroportin axis is the key mechanism involved in metabolic health. This study aims to investigate the intertwined relationship between vitamin D status and iron homeostasis in metabolic syndrome induced by a high-fat high-fructose (HFHF) diet in rats. The experimental groups were as follows: G1; negative control, G2; positive control, G3 and G4 (balanced diet and supplemented with Vit.D3 (12 and 24 µg/Kg b.wt respectively twice/week). G5 and G6 (HFHF diet and supplemented with Vit.D3 (12 and 24 µg/Kg b.wt respectively twice/week). Various biochemical, molecular, and histological parameters were evaluated in serum and liver tissue homogenate. The results showed …

Gc-Ms Quantification And Identification Of Phytochemical Profiling, Potential Antioxidant Activity By Dpph, And Mineral Elements Of Eggplant Powder (Solanum Melongena) In Sulaymaniyah City, Iraq, Srwa Nasraldeen Majeed

Baghdad Science Journal

Solanum melongena, the plant used as a food and medical remedy known as eggplant, has anti-inflammatory, antioxidant, and anti-cancer properties. It is one of the vegetables that is most widely cultivated worldwide and has a wide range of vegetable sizes, colors, and shapes. This study looked at thirteen chemical compounds in the plant using gas chromatography and mass spectrometric detection (GC-MS). The gathered information verified that the object included thirteen chemical components, likes 2 — pentanone-4-hydroxy 4- methyl% 2.30, 1,3-dioxolane-4-methanol %0.17, formic acid %0.86, methenamine-methoxy %4.528,1,2,3-propanetriol (glycerin) %40.86, tetradecane%0.16, hexadecane%0.27, octadecane %0.16, myristic acid %3.14, nonadecane%0.44,9,12-octadecadienoic acid linolenic acid %0.43, …

Determination Uranium And Its Isotopes In Biological Samples Of Smokers, Abdulhussein A. Alkufi, Mohanad H. Oleiwi, Ali Abid Abojassim, Noor Ulhuda G. Mohammed, Ali Saeed Jassim, Michele Guida

Baghdad Science Journal

This study was conducted in the Najaf Governorate- Iraq, to analyze biological samples from smokers and non-smokers. The samples, including blood serum, urine, hair, and nails, were used as biomarkers to determine uranium concentrations (UC) and isotopes (238U, 235U, and 234U). Using a natural exposure method, the nuclear track detector (CR-39, UK) was utilized to measure these Uc in the samples. Seventy-five samples of blood serum, urine, hair, and nails were collected for smokers of healthy people and fifty samples for non-smokers of healthy people in five age groups. This study was based on age and smoking to compare the …

A Histological Study Of The Black-Winged Kite's Retina (Elanus Caeruleus, Desfontaines, 1789), Shaimaa Awad Abid, Mukhtar Khamis Haba

Baghdad Science Journal

The study showed the retina of the diurnal invasive raptor Elanus caeruleus is avascular and supplied nutrition and oxygen by the choroid and pecten oculi. The retina includes two layers: the outer layer is called the pigmented epithelium, and the inner layer is the neural layer. The neural layer consists of nine layers: visual cells layer, outer limiting membrane, external nuclear layer, external plexiform layer, internal nuclear layer, internal plexiform layer, ganglion cell layer, nerve fiber layer and inner limiting membrane. The visual cell layer consists of double cones, single cones and rods, and the cones are more than the …

Effect Of Chemically Synthesis Compared To Biosynthesized Zinc Oxide Nanoparticles Using Extract Of Vitex Agnus On The Expression Of Mexab-Oprm Efflux Pump Genes Of Multi-Drug Resistance Pseudomonas Aeruginosa, Shams Al-Shomos Khalis Khames, Shatha Thanoon Ahmed

Baghdad Science Journal

The current study's goal was to find out how the expression of the efflux pump genes (MexAB-OprM) in MDR P. aeruginosa isolates was influenced by chemically manufactured Zinc Oxide Nanoparticles using sol-gel method as compared to biosynthesized Zinc Oxide Nanoparticles using Vitex agnus-castus leaves extract. PCR analysis was used to confirmthe the presence of 16S rRNA gene in all 16 P. aeruginosa isolates The findings indicated that P. aeruginosa tested positive for 16S rRNA (100%), and 7 (43.75%) of the isolates were MDR. All MDR isolates carried MexA, MexB and OprM genes.The Vitex extract's GC-MS analysis exposed the existence of …

The Texas Electorate's Views Of Health Care As A Human Right, Community Health Centers, And Certain Matters Of The Health Care Safety Net, Scott Elphingstone

Graduate Liberal Studies Theses and Dissertations

In a country in which the government does not recognize a right to health care,social safety nets are the last hope for persons without insurance or other means to pay for needed care. In United States, community health centers, hospital emergency rooms, and private charities comprise that safety net. Community health centers offer a practicable alternative for politicians and citizens who want to help improve the lives of persons who struggle to access health care. This dissertation reviews the political history of community health centers from their founding as part of the War on Poverty in the 1960s through Democratic …

Global, Regional, And National Progress Towards The 2030 Global Nutrition Targets And Forecasts To 2050: A Systematic Analysis For The Global Burden Of Disease Study 2021, Michael Benjamin Arndt, Aleksandr Y. Aravkin, Natalia V. Bhattacharjee, Julian Chalek

Open Access archive

Background: The six global nutrition targets (GNTs) related to low birthweight, exclusive breastfeeding, child growth (ie, wasting, stunting, and overweight), and anaemia among females of reproductive age were chosen by the World Health Assembly in 2012 as key indicators of maternal and child health, but there has yet to be a comprehensive report on progress for the period 2012 to 2021. We aimed to evaluate levels, trends, and observed-to-expected progress in prevalence and attributable burden from 2012 to 2021, with prevalence projections to 2050, in 204 countries and territories. Methods: The prevalence and attributable burden of each target indicator were …

Complexities, Benefits, Risks, And Clinical Implications Of Sodium Bicarbonate Administration In Critically Ill Patients: A State-Of-The-Art Review, Akram M. Eraky, Yashwanth Yerramalla, Adnan Khan, Yasser Mokhtar, Alisha Wright, Walaa Alsabbagh, Kevin Franco Valle, Mina Haleem, Kyle Kennedy, Chad Boulware

GME Publications

Sodium bicarbonate has been used in the treatment of different pathologies, such as hyperkalemia, cardiac arrest, tricyclic antidepressant toxicity, aspirin toxicity, acute acidosis, lactic acidosis, diabetic ketoacidosis, rhabdomyolysis, and adrenergic receptors' resistance to catecholamine in patients with shock. An ongoing debate about bicarbonate's efficacy and potential harm has been raised for decades because of the lack of evidence supporting its potential efficacy. Despite the guidelines' restrictions, sodium bicarbonate has been overused in clinical practice. The overuse of sodium bicarbonate could be because of the desire to correct the arterial blood gas parameters rapidly instead of achieving homeostasis by treating the …

The Vagina Dentata: A Case For Unlocking Mouths, Loosing Hips, And Spreading The Gospel Of Healing Women's Sexual Performance Anxiety, Alisha Lola Jones

Yale Journal of Music & Religion

This article explores how vagina dentata folklore—stories and imagery about a mythical "toothed vagina"—connects to the ways Black religious communities often cultivate silence around women’s sexual lives, particularly within the “Worth the Wait” and Word of Faith movements. Ignited by womanist religious ethnographer Monique Moultrie’s scholarship on sexual silence in these movement, I take seriously the musicological chasm by exploring how these ministries influence Black women’s sexual agency and moral decision-making through inequitable theological procedures and discourses. The vagina dentata metaphor emerges as a symbol of constrained appetites—respiratory (larynx), digestive (intestine, anus), and reproductive (uterus, vagina)—reflecting broader sociocultural and religious …

Graduate Student Journal Article Writing Group: Creating Community Around Publishing, Gabrielle Brehne, Catherine Baird, Alicia Remolde

Journal of Graduate Librarianship

At Montclair State University, the online and outreach librarian and the assistant director of the Center for Writing Excellence paired up to create a supplemental program to support graduate students seeking to publish journal articles. A graduate assistant joined the team and created content based on Wendy Laura Belcher’s book Writing Your Journal Article in Twelve Weeks. We will discuss how we collaborated to establish this writing group and what we learned from the experience. A journal article writing group is a great addition to any graduate program, and we hope our story will inspire others.

Tcas Benchmark, Vol. 14, No. 11. 2000, Wendy Lockwood, Marvin Glasgow, Jim Blanton

North Texas Archeological Society Records

Volume fourteen and issue eleven of TCAS Benchmark.

Predicting Aminoglycoside-Induced Hearing Loss Among Mdr-Tb Infected Individuals In South Africa, Hyejeong Hong

Sigma Foundation for Nursing Research Grant Reports

This study aimed to estimate the risk of AG-induced hearing loss among MDR-TB infected individuals in South Africa.

Recipes For Revision: Digesting American Empire In The Philippines Via Filipina Literature In Spanish, Adam Lifshey

Kritika Kultura

This essay investigates the intersections of American empire and American feminism via literature by Filipinas in Spanish. Texts written in Manila by hispanophone Filipinas who were also American subjects and American nationals present a defamiliarizing phenomenon that casts anew standard historical-literary accounts of the 20th century United States. The literary output of Maria Paz Zamora, for instance, reveals an America that emerges on shores not commonly taken to be American at all and yet are more indicative, arguably, of the modern United States than any other. Paz Zamora was the first Asian woman to produce a short story collection in …

Building Successful Justice Worker Programs: Emerging Insights From Research And Practice, Rebecca L. Sandefur, Matthew Burnett

Alaska Law Review

America's deep access to justice crisis has long seemed intractable. But new and potentially transformative models for giving people access to legal services and to their own law are emerging around the country. Among the most promising of these are community justice workers. These are people already trusted in their communities, such as social workers, librarians, health aides, community leaders, teachers, mediators, and everyday citizens who are trained to help people understand and act on the legal challenges involved in critical life issues. These issues implicate basic needs like nutrition, health, income security, shelter, education, and care of dependents, and …

Minimizing Infant Injury Risk By Utilizing Parental Education In A Primary Care Setting, Courtney Munroe, Erin Kuehl, Rachel Mahlberg

Doctor of Nursing Practice Projects: College of Nursing

Introduction

Accidental injury and death to infants has been correlated to lack of proper education to parents of infants in the primary pediatric care setting. Sudden infant death syndrome (SIDS) and unintentional injuries were the second and third leading causes of post neonatal death during this period of time (Centers for Disease Control and Prevention [CDC], 2016). Studies have found that motor vehicle accidents are a leading cause of child injury and death for infants under 12 months of age. The CDC found that drowning, suffocation, and poisoning were other leading causes that contributed to child injury and death rates …

The Illegal Trade Of Marine Wildlife: A Review Of Consequences And Strategies To Combat The Trade, Kaitlyn Shaw

Seattle Journal of Technology, Environmental, & Innovation Law

An enduring challenge in assessing the risk of extinction for marine animals lies in our need to consume them. Many nations, including the United States, invest substantial resources in supporting fishery businesses to locate, harvest, and market ocean wildlife, with comparatively small allocations for their protection. Despite the existence of numerous state, national, and international laws dictating how and when animals can be harvested, achieving sustainable catch levels remains elusive. Especially when adding in the constant battle against organized crime groups, combatting the marine wildlife trade almost seems impractical. This comment analyzes and argues for a more comprehensive approach to …

The Lived Experiences Of Female Undergraduates At A Private University Regarding Foodways And Wellness: An Interpretive Phenomenological Analysis, Kelly Green Kearns

Dissertations - ALL

This dissertation study outlines the topic of food and wellness for female undergraduate college students at a private university in the northeastern US. An extensive literature review on the topic of human interactions with food and wellness as well as the potential impact on female undergraduate students is provided, followed by a proposed qualitative study. This dissertation describes the qualitative method of Interpretive Phenomenological Analysis (IPA) using semi-structured interviews and member-checking meetings to learn about the experiences of eight female undergraduate students at a private university’s experiences with food, eating, sourcing, cooking, and sharing and how these behaviors impact and …

Gatekeeper, Keep Thyself: How Impairment Impacts The Integration Of Counselor Wellness Competencies, Curtis Lee Taylor

Electronic Theses and Dissertations

This quantitative study examined counselor educators’ beliefs regarding the importance of Counselor Wellness Competencies (CWCs) and how effectively they teach them to their counselors-in-training (CIT). This study focused on significant relationships between the importance and effective teaching, self-care, and burnout. Counselor educators who place higher importance on the CWCs reported having higher self-efficacy in teaching them. The findings suggest that counselor educators with more self-care behaviors experienced less burnout and were better able to show congruence between the importance and effective teaching of the CWCs. The conclusion of this report explores limitations and directions for future research.

Factors Affecting Involvement Of Parents Of Students With Learning Disabilities In Saudi Elementary Schools, Mohammed Alyahya

Electronic Theses and Dissertations

The research explores the factors that influence parental involvement in school children with learning disabilities in Riyadh, Saudi Arabia. Understanding these factors is crucial, as parental involvement is widely recognized as essential for the academic success of children, particularly those with learning disabilities. This study used a quantitative approach to collect data from parents of students with learning disabilities, including parents' age, gender, income, employment status, and parental beliefs (responsibilities and capabilities). The findings reveal that parental beliefs regarding their responsibilities towards their child's education are the only significant predictor of parental involvement. In contrast, other variables, including age, gender, …

Enhancing Concrete Sustainability With Self-Healing Technologies, Al Shimaa Abdullatif

Theses and Dissertations

Thanks to its strength, durability and affordability, Portland cement concrete is the most commonly used building material worldwide. However, concrete cracking is inevitable due to numerous factors including shrinkage, exposure to external chemicals, internals reactions, excessive loads, to name but a few. Self-healing is a promising technique that can enable concrete to autogenously heal cracks and alleviate much of the damage. Such healing can without a doubt extend the service life with less need for external repair works therefore it contributes to sustainability. Over the years, several means of self-healing agents have been explored including bio-based procedures and the incorporation …

The Cumulative Effect Of Ellagic Acid And Carnosic Acid Attenuates Oxidative Events During Diabetic Wound Healing: In Different Applications And On Different Days, Eli̇f Naz Gürsoy, Kanuni̇ Barbaros Balabanli, Fatma Nur Tuğcu Demi̇röz, Şule Coşkun Cevher

Turkish Journal of Biology

Background/aim: The hyperglycemic environment in diabetes disrupts normal wound-healing processes, leading to chronic wounds. This study investigated whether the combination of the phenolic compounds Ellagic acid and Carnosic acid shows synergistic effects on diabetic wound healing and oxidative parameters in diabetic rats.Materials and methods: In this study, diabetic rats were divided into control, untreated, Carbopol 974P treated, topical treatment, and oral gavage treatment. Ellagic acid and Carnosic acid combination were applied topically and oral gavage to the full-thickness excisional wounds of all animals except the control group. We investigated oxidative events by malondialdehyde, glutathione, nitric oxide, protein carbonyl, collagen spectrophotometrically, …

Defining The Chondrocyte “Mechanome”: How Mechanosensitive Ion Channels Trpv4 And Piezo1 Drive Changes In Gene Expression To Affect Cell Behavior And Cartilage Health, Daniel Raymond Palmer

McKelvey School of Engineering Graduate Student Theses & Dissertations

Chondrocytes, the only native cell population of cartilage, utilize mechanosensitive transmembrane ion channels to sense mechanical forces. Transient Receptor Potential Vanilloid 4 (TRPV4) is activated by physiologic levels of load (resulting in ~10% tissue deformation) while PIEZO1 is activated by supraphysiologic levels of load (resulting in >50% tissue deformation). TRPV4 activation promotes the expression of a limited number of chondrogenic genes and the production of vital cartilaginous matrix proteins, while PIEZO1 activation drives cell death and senescence, cytoskeletal weakening, and production of catabolic mediators, which contribute to the development of osteoarthritis (OA). However, the path connecting activation of these channels …

Multimodal Representation Learning Frameworks For Modeling Progression And Heterogeneity In Alzheimer’S Disease, Sayantan Kumar

McKelvey School of Engineering Graduate Student Theses & Dissertations

Alzheimer’s Disease (AD) is the leading cause of dementia, characterised by cognitive and functional impairments that disrupt daily activities. Different clinical modalities such as neuroimaging biomarkers, cognitive assessments, fluid biomarkers and genetic data provide unique and complementary information, contributing to a more comprehensive understanding of disease progression and heterogeneity in disease characteristics. With recent advancements in computational capabilities, particularly in deep learning, multimodal representation learning frameworks aim to integrate diverse clinical modalities into a cohesive framework, capturing the most significant patterns within each modality. Existing data-driven multimodal representation learning frameworks in AD research have two major limitations. First, AD progresses …

Challenges To Reproductive Justice: An Ethical Analysis Of Reproductive Technologies And Disparities, Courtney Brenner

Electronic Theses and Dissertations

This dissertation analyzes the Reproductive Justice Framework to describe possible solutions to the ethical challenges related to reproductive healthcare disparities. Various frameworks to support reproductive equity fail to address the challenges marginalized individuals face in accessing reproductive health services. The four ethical principles of autonomy, beneficence, nonmaleficence, and justice serve as foundational tools to support reducing these disparities. This dissertation uses the Reproductive Justice Framework to analyze the unequal distribution of harms among marginalized women. It highlights how access to care, such as Assisted Reproductive Technologies (ART), is disproportionately inaccessible to marginalized women. Then, it discusses the relationship between marginalized …

Muslim Spirituality As A Foundation In Bioethics For Patient Encounters In Health Care, Sara Rahman

Electronic Theses and Dissertations

Spirituality plays a major role in decision making for individuals with faith-based values. There is often hesitation to discuss the role of faith in healthcare as a core value and coping mechanism. The growing cultural diversity amongst patients and physicians has increased the need to understand eastern religious principles and incorporate them into bioethical guidance. Even as the 2nd largest religion in the world, Islam has not been sufficiently integrated into religious bioethics in western medicine. Muslim populations of patients and physicians are growing, increasing the need for better understanding of how Islamic principles impact healthcare delivery. Although Islamic law …

Multimodal Representation Learning Frameworks For Modeling Progression And Heterogeneity In Alzheimer’S Disease, Sayantan Kumar

McKelvey School of Engineering Graduate Student Theses & Dissertations

Alzheimer’s Disease (AD) is the leading cause of dementia, characterised by cognitive and functional impairments that disrupt daily activities. Different clinical modalities such as neuroimaging biomarkers, cognitive assessments, fluid biomarkers and genetic data provide unique and complementary information, contributing to a more comprehensive understanding of disease progression and heterogeneity in disease characteristics. With recent advancements in computational capabilities, particularly in deep learning, multimodal representation learning frameworks aim to integrate diverse clinical modalities into a cohesive framework, capturing the most significant patterns within each modality. Existing data-driven multimodal representation learning frameworks in AD research have two major limitations. First, AD progresses …

Chelidonic Acid Abrogates Oxidative Stress And Memory Dysfunction In Experimental Aging Rats, Feri̇de Ni̇hal Si̇nan, Emel Serdaroğlu Kaşikçi, Burcu Çevreli̇

Turkish Journal of Biology

Background/aim: In an aging model established in male Wistar albino rats via the administration of D-galactose (D-gal), the aim of this study was to examine the effects of chelidonic acid on cognitive functioning and the levels of glutathione (GSH), malondialdehyde (MDA), Total antioxidant status (TAS), and brain-derived neurotrophic factor (BDNF).Materials and methods: Thirty-two Wistar albino (three month old) male rats (n = 8) were used. Group 1: Control (C), Group 2: Chelidonic acid (CA) (2 mg/kg oral gavage), Group 3: D-galactose (D-gal) (150 mg/kg, s.c.), Group 4: D-gal (150 mg/kg) + CA (2 mg/kg) (DC). Following an overnight fast, the …

Sparkled: Social Programming In Kids Affects Risk Of Latent Endothelial Disease, Rebecca Drakowski

Theses & Dissertations

Background: Social Health Programming (SHP) is a holistic intervention that can empower communities to address modifiable risk factors for poor cardiovascular health, including suboptimal nutrition or psychosocial stressors. SHP participation has been shown to increase dietary intake of fruits and vegetables, decrease perceived stress, and improve cardiovascular endurance. However, it is unknown how SHP participation during adolescence affects carotenoid serum levels, hair cortisol concentrations (biological marker of chronic stress), or vascular reactivity index (VRI; measure of subclinical cardiovascular health).

Methods: Adolescent girls and young adult women (12–29-year-old) were enrolled in this observational cohort study. Serum, hair, and saliva samples were …

Development Of A Streptococcus Mutans Biofilm Model On A Typodont Platform To Investigate Its Dynamics In Orthodontics, Hibah Chughtai

Theses & Dissertations

Introduction: Biofilm formation plays a significant role in dental health, resulting in plaque accumulation, which can lead to caries and oral diseases. Streptococcus mutans (S. mutans) is a key bacterium involved in this process. The goal of this study was to establish a protocol for the development of an S. mutans biofilm on dental typodont teeth to analyze the effects of orthodontic brackets on biofilm formation. Understanding these dynamics is critical for developing strategies to mitigate biofilm accumulation during orthodontic treatment. Methods: S. mutans biofilms were cultivated under three conditions: 96-well tissue culture plates, S. mutans inoculated non-bracketed …

Retrospective Derivation Of A Causal Pathway For Diabetic Ketoacidosis In Adult Patients With Type 2 Diabetes Mellitus, Jeffrey A Kline, Nicholas A Wesner, Amina T Sharif, Richard T Griffey, Phillip D Levy, Robert D Welch, George Grunberger

2020-Current year OA Pubs

BACKGROUND: Type 2 ketone-prone diabetes mellitus (T2KPDM) is thought to occur in men of African descent, with obesity who experienced prolonged hyperglycemia; the role of medication non-adherence as a contributing cause remains unstudied.

RESEARCH DESIGN AND METHODS: This was a retrospective study of unique adults (>18 years) who sought emergency care one of four hospitals in the greater Detroit area. Patients were identified on the basis of a laboratory order for a ß-hydroxybutyrate concentration. Two research coordinators abstracted 119 data fields. Patients were divided into four phenotypes: (1) no prior DM, (2) type 2 DM without prior ketosis, (3) …