Digital Commons Network^™

In Silico Exploration Of Alstonia Scholaris Secondary Metabolites As Antioxidant: Molecular Docking With Key Enzymes And Toxicity Prediction, Arifa Rizqi Nafisa, Anggiresti Kinasih, Muhammad Luqman Hakim, Arif Nur Muhammad Ansori

Makara Journal of Science

Degenerative diseases associated with oxidative stress necessitate the development of effective antioxidant therapies. Alstonia scholaris, a medicinal plant known for its diverse pharmacological properties, was investigated for its antioxidant potential using computational approaches. This study employed molecular docking to evaluate the interactions between bioactive compounds from Alstonia scholaris and key antioxidant target proteins, including lipoxygenase, CYP2C9, NADPH oxidase, and bovine serum albumin. Pharmacokinetic analyses based on Lipinski’s Rule of Five, along with toxicity assessments, were conducted to evaluate the compounds’ drug-likeness and safety profiles. The results demonstrated that (+)-Dicentrine exhibited the strongest and most stable binding affinity toward lipoxygenase …

Differential Gene Expression Of Ethylene Biosynthesis And Signaling Associated With Climacteric Behaviors In Indonesian Melon, Vida Rahma Latifah, Adib Fakhruddin Yusuf, Karso Suryo Putro, Dian Sartika, Anjar Tri Wibowo, Awik Puji Dyah Nurhayati, Karlia Meitha, Miftahudin Miftahudin, Budi Setiadi Daryono

Makara Journal of Science

Fruit ripening in melon (Cucumis melo L.) is a complex developmental process that is characterized by the coexistence of climacteric and non-climacteric varieties within the same species. This study characterized the ripening behavior of four local Indonesian melon cultivars (“Melona”, “GMP”, “Tacapa Gold”, and “Kinaya”) by integrating morphophysio-logical traits with transcriptional expression analysis of ethylene biosynthesis (CmACS, CmACO) and signaling (CmATH, CmEREBP) genes. The results revealed a strong agreement between the phenotypic traits and molecular regulation. “Melona” and “GMP” exhibited a strong climacteric profile, which was characterized by natural fruit abscission, sweet aroma …

Network Pharmacology Of A Decaffeinated Green Coffee–Turmeric Combination: Potential Therapeutic Activity Against Hypertension And Diabetes Mellitus, Feri Eko Hermanto, Mohammad Saifur Rohman, Victor Alvianoes Guterez Hose, Mifetika Lukitasari, Dwi Adi Nugroho, Nashi Widodo, Inggita Kusumastuty

Makara Journal of Science

Decaffeinated green coffee and turmeric are recognized for their protective effects against hypertension (HTN) and diabetes mellitus (DM). Combining them into a functional drink, green coffee and turmeric (GCT), offers potential health benefits for managing these conditions. This study explored the bioactivity of GCT in HTN and DM through network biology, identifying intersecting protein targets and their roles in inflammation and glucose metabolism. Key proteins identified were AKT1, CCL2, CXCL8, IL-1β, and IL18. Molecular docking revealed that GCT compounds, particularly Cafestol, Chlorogenic Acid, Kahweol, Curcumin, and Desmethoxycurcumin, interacted strongly with AKT1 at its allosteric site, potentially inhibiting its activity. However, …

Organic Cherry Pest Management, Marion Murray, Ann Mull

All Current Publications

Tart cherry (Prunus cerasus) and sweet cherry (P. avium) are important commercial crops and popular backyard trees. Tart cherries are commonly processed into dried or canned products, while sweet cherries are generally eaten fresh. Organic cherry production in the Intermountain West can be challenging because of pests such as western cherry fruit fly and arid growing conditions. However, with careful planning and appropriate management practices, it is possible to produce a good crop using organic pest management strategies. This fact sheet outlines general, pest, and disease management options.

Home On The Range: Where Deer And Antelope Compete With Feral Horses For Limited Resources, Katelyn Davies, Hannah B. Klugman, Kathryn A. Schoenecker, David C. Stoner

All Current Publications

Given projections for continued drought conditions in the West, a better understanding of how native wildlife respond to competition with feral horses will be critical for developing effective conservation programs in the future. This fact sheet provides information on feral horses and presents study data comparing their use of water resources with that of native wildlife.

Musculoskeletal Disorders, Care Burden, And Sarcopenia: A Preliminary Study On Family Caregivers, Shu-Yuan Lin

International Nursing Research Congress (INRC)

Background: Family caregivers bear a high risk of developing musculoskeletal disorders (MSD), which may precipitate sarcopenia and care burden. This study hypothesizes that the occurrence of MSDs may be related to caregiver burden and sarcopenia among middle-aged and older family caregivers.

Study Purposes: (1) To investigate the incidence of MSDs, sarcopenia, and the level of care burden among middle-aged and older family caregivers; (2) To identify the correlations between MSDs, sarcopenia, and care burden.

Methods: A cross-sectional questionnaire survey was conducted. Family caregivers who received services from the Caregivers Association or home care services and met the inclusion criteria, including …

Understanding Men's Health In Down Syndrome, Brian Chicoine

Advocate GME

Males with Down syndrome may experience certain health conditions differently than females and may also face unique health concerns throughout their lives. In this webinar, Brian Chicoine, MD, will discuss common health topics affecting males with Down syndrome, including growth and development, muscle health, mental health, fertility, aging, and cancer risk. Attendees will learn about recommended health screenings, signs and symptoms to watch for, and practical ways to support lifelong health and well-being. This session is designed to help attendees better understand the health needs of men with Down syndrome and feel more confident navigating healthcare decisions. The webinar will …

Shallow Margin Fish Biomass Estimates In Lake Victoria Using Horizontal-Beam Acoustics, Yang Yang, Roland Proud, Robert Kayanda, Collins Ongore, Mboni Elison, Hillary Mrosso, Benedicto B Kashindye, Andrew S Brierley, Alina M Wieczorek

School of Biological and Marine Sciences

No abstract provided.

My Negotiation Chatbot Toby And Pedagogical Governance, Renee Henson

Journal of Science & Technology Law

No abstract provided.

Building On Sand: Ai Law And The Failures Of Alignment, Claire Boine

Journal of Science & Technology Law

AI alignment is increasingly in the spotlight. However, from a technical concept, the term has been broadened to cover all sorts of potential harms by advanced AI systems. This Article disambiguates three different problems: ensuring that systems pursue intended objectives through acceptable means, deciding which values should guide their behavior, and governing private companies whose incentives diverge from those of society. Drawing on technical research and documented incidents, the Article explains why goal alignment deserves serious attention without requiring claims about human-like intelligence. It then shows how value alignment can reframe normative conflict as an engineering problem and divert attention …

Effect Of A Pressure Injury Prevention Bundle On Compliance And Staff Attitudes In A Medical Icu, Elizabeth L. Woods

International Nursing Research Congress (INRC)

Background: Hospital-acquired pressure injuries (HAPIs) are considered preventable yet remain prevalent in intensive care units (ICUs), where critically ill patients face increased risk due to immobility, hemodynamic instability, and complex care needs. This quality improvement (QI) project aimed to evaluate whether implementing a pressure injury prevention bundle (TEAMS) would improve compliance with preventive measures and staff attitudes toward HAPI prevention in a medical ICU.

Methods: A pre-post intervention design was conducted in a 17-bed medical ICU at a tertiary academic hospital. The TEAMS bundle included five components: Turn teams, Education, daily Assessments, a multidisciplinary approach, and daily Skin care. The …

Imsa 2026 Profile, Office Of College And Academic Counseling

IMSA Profile

The nationally-ranked Illinois Mathematics and Science Academy (IMSA) develops creative, ethical leaders in science, technology, engineering and mathematics. As a teaching and learning laboratory created by the State of Illinois, IMSA enrolls academically talented Illinois students in its tuition-free residential Academy for grades 10-12. Students are challenged with a rigorous curriculum designed to develop them into problem solvers and critical thinkers. Notable IMSA students include YouTube Co-Founder Steve Chen, PayPal Co-Creator Yu Pan, Yelp Co-Founder Russell Simmons, SparkNotes and OkCupid Co-Founder Sam Yagan, and Hearsay Social Founder Clara Shih.

Fitness Standards For Police, Kam Robles

PNHA Review

This research addresses the inherent stressors within police work and the health and wellness problems prevalent among law enforcement officers. Police officers are at a higher risk of many of the health concerns currently plaguing the population of the already unhealthy United States. Of particular note is that back injury and pain stands out as potentially the most prevalent among the health issues experienced by law enforcement personnel. Worsening this fact is the recent trend of law enforcement administrators shying away from the issue of the unhealthy employees of law enforcement agencies. The solution of implementing widespread voluntary physical fitness …

Social Innovation As A Catalyst To Achieving The United Nations Sustainable Development Goals (Sdgs), Patricia Okolo

PNHA Review

This research explores the re-shaping role of social innovation in advancing the Sustainable Development Goals (SDGs), developed by the United Nations in 2015. In the midst of global challenges such as poverty, inequality, and climate change, this research examines social innovation as an important mechanism for achieving sustainable development. The article highlights the significant contributions of social innovation across various sectors, emphasizing its ability to address unmet social needs, promote environmental sustainability, and foster economic development. It identifies critical factors for the success of social innovation, including community involvement, scalability, access to resources, and supportive policy environments, and highlights the …

The Psychology Of Healthy Aging: A Blend Of Cognitive And Behavioral Aspects For Staying Healthy, Esther B. Noah

PNHA Review

Human life expectancy has increased in most parts of the world with a noticeable demographic shift toward a larger population of older adults. This increase and shift have created an unexpected gap in our healthcare system and society. With these changes, how can older adults be guaranteed increased longevity, quality of life, and a healthy life span? This article explores the psychology of healthy aging, emphasizing that proactive health management plans and positive health behaviors contribute to healthy aging among the older adult population. While primary data collection through interviews was conducted to support the study, the analysis primarily relies …

A New Age Of Leaders: Examining The Empowering Effect Of Collaborative Leadership In Nonprofit Organizations, Colton C. Hyble

PNHA Review

In the changing environment in the nonprofit sector, leaders are under increasing pressure to satisfy stakeholders and bring change to their communities. The collaborative leadership style, proposed and built upon by various authors in the twentieth century, is one potential solution. A theoretical analysis was conducted to understand the collaborative style, its strengths and weaknesses, and its applicability to the nonprofit sector. Results showed overwhelmingly positive findings in the impact on the organization, highlighted by increased organizational performance, a positive workplace environment, and superb employee job satisfaction. Few drawbacks and potential pitfalls exist in slowness, the possibility of a narrow …

Differences In Mental Toughness Among Mixed Martial Artists And Physically Active Individuals, Savannah M. Calleja, Soleil Ramos, Victoria Potvin, Anthony A. Ricci, Gabriel J. Sanders, Corey A. Peacock

Journal for Sports Neuroscience

Mixed Martial Arts (MMA) is a physiological and psychological demanding sport. While the majority of the literature conducted in MMA regards physiological health and risk of injury, researchers are beginning to assess the psychological profiles of MMA athletes. Previous studies have evaluated mental toughness (MT) within MMA; however, no study has examined MT in MMA athletes at the professional division. Therefore, the primary purpose of this research was to evaluate the difference in mental toughness between professional MMA athletes and physically active individuals. Secondary aims are to evaluate potential variations in mental toughness within the professional level between champion and …

Expression Of Follicle Stimulating And Luteinizing Hormone Receptors In Porcine Testes After Timing The First Vaccination For Immunocastration, Sayamon Srisuwatanasagul, Rungrueang Yodsheewan, Amornthep Archawakulathep, Suvaluk Seesupa, Kongkiat Srisuwatanasagul, Atthaporn Roongsitthichai, Siriluck Juntautsa

The Thai Journal of Veterinary Medicine

This study aimed to examine the expression of follicle stimulating hormone receptor (FSHR) and luteinizing hormone receptor (LHR) in the testes of male fattening pigs based on the timing of the first immunocastration dose. A total of 24 male pigs were randomly assigned to 3 groups: C (n=8) consisted of only intact pigs, T1 (n=8) contained those immunocastrated at 15 and 19 weeks of age, and T2 (n=8) was composed of those immunocastrated at 9 and 19 weeks of age. The expression of FSHR and LHR was evaluated using H-score from immunohistochemistry and protein band intensity from Western blotting. Immunohistochemistry …

Whose Turn, Not Who's Best: Round-Robin Rotation Over A Boolean Liveness Predicate For Unranked Local Business Discovery, Thon Ly

Defensive Publications Series

We specify an unranked local-business discovery system in which candidates are ordered by a publicly verifiable round-robin rotation (algorithm, per-cycle seed and recomputation tool published) and admitted by a boolean activity predicate instead of a ranking score. Admission asks only whether a participant's account balance has returned to zero within one published, global time window; amplitude and volume are excluded, so admission is a rate that cannot be accumulated or purchased. The discovery turn belongs to the payer, not the merchant: candidates are presented when a user spends from a forward-only, locality-restricted gratuity account, so the system has no merchant-facing …

Sugary Beverages And The Rise Of Chronic Disease Among Hispanic Women, Jailene Lemus Hurtado, Natalia Andrea Villegas Rodriguez

International Nursing Research Congress (INRC)

Background and Purpose: Cardiovascular disease (CVD) is the leading cause of death and a major source of morbidity among Hispanics in the U.S. (1,2). Sugar-sweetened beverages (SSBs) are known to be associated with an increased risk of CVD, diabetes and obesity (3,4). However, there is a lack of information concerning SSB consumption patterns and perceptions of related health risks among Hispanic women in the U.S. This study aims to investigate SSB consumption patterns and perceptions among Hispanic women.

Methods: This cross-sectional descriptive study included 40 fluent Spanish-speaking Hispanic women ages 18 to 44 from North Carolina who participated in a …

Social Frailty In Asia: A Scoping Review Of Interventions, Gaps, And Priorities, Julienne Ivan Dagondon Soberano, Jed Montayre

International Nursing Research Congress (INRC)

Aim: Social frailty (SF) is a multidimensional state of social vulnerability linked to adverse outcomes in older adults. Asia’s rapidly aging population poses challenges for health systems, particularly in addressing SF-related conditions. This scoping review aimed to describe existing SF interventions in Asian countries, assess evidence volume and characteristics, and identify research gaps.

Methods: A systematic search of eight databases (PubMed, Scopus, CINAHL, Embase, Web of Science, PsycINFO, Cochrane Library, Google Scholar) identified English-language studies published from January 2020 to September 2025. The review followed Arksey and O’Malley’s framework and PRISMA-ScR guidelines. Interventions were synthesized across the care continuum (prevention, …

To Spend Or Not To Spend: Strengthening Congressional Oversight On Executive Impoundment, Grant Scherer

Emory Law Journal Online

The [H]ouse of [R]epresentatives cannot only refuse, but they alone can propose, the supplies requisite for the support of government. . . . This power over the purse may, in fact, be regarded as the most complete and effectual weapon with which any constitution can arm the immediate representatives of the people, for obtaining a redress of every grievance, and for carrying into effect every just and salutary measure.

James Madison, Federalist No. 58[1]

While the President may initiate the annual federal budget process with his or her budget request, the Constitution confers the “power of the purse” on …

Toxic Plants In Zimbabwe: The Lantana Camara Species, Frank Kapungu, Cecilia Masvingwe

Poisonous Plant Research (PPR)

Lantana camara is a major invasive plant species in Zimbabwe. Its toxic effects pose a threat to livestock production, biodiversity, and development. A survey was carried out throughout the country to investigate the distribution of L. camara in Zimbabwe and assess the extent of its spread. Identification was done by toxicologists with the support of an experienced botanist from the National Herbarium of Zimbabwe. The location of the plants was identified using a portable Garmin eTrex® 10 Handheld GPS navigation device., and the coordinates were recorded. Quantum Geographic Information System (QGIS) was used to plot the map. L. camara was …

Holding The Line: Teacher Resilience And Engagement In Myanmar’S Conflict-Affected, Non-State Schools, Lugyi No, Hilary Lustick

Journal of Education Studies

This qualitative study explores teacher resilience, professional engagement, and informal leadership in community-led schools located in conflict-affected areas of Myanmar. The study draws on two online focus group discussions with 14 high school teachers selected through purposive sampling. The research instrument was a semi-structured focus group discussion protocol. The discussions were conducted in the Myanmar language, and the data were analyzed using inductive thematic analysis. The findings indicate that teachers sustain resilience through moral purpose, professional commitment, and strong relational ties with students, peers, and local communities. In the absence of formal governance structures, teachers assume informal leadership roles by …

High-Resolution Taxonomic Assessment Using Pacbio 16s Rrna Sequencing Of Farm Animal Slurry, Broiler Waste And Anaerobically Digested Wastewater Treatment Sludge And Description Of Soil Microbiota, Natalia Alija-Novo, Leonard Koolman, Karl G. Richards, Paul Whyte, Declan Bolton

Research Outputs: 2025-Present

The application of organic wastes as fertilisers is important for sustainable agriculture, provided that resulting changes in microbial communities do not disrupt nutrient cycling or soil fertility. To the authors’ knowledge, this study was the first to use PacBio 16S rRNA sequencing to characterise soil microbiota changes following waste application to land. This technology provides high taxonomic resolution, improving the characterisation of complex soil microbial communities. To assess the microbiota of five organic wastes and describe soil microbiota following field application, 18 plots received each waste in triplicate at nitrogen-equivalent rates simulating band spreading. Soil cores were collected at 0, …

Spectrum, Volume 57, Issue 2, Sacred Heart University

Newspapers (Obelisk & Spectrum)

Highlights include:  Building the Future -- Pouring on Park Ave! --  The RD Is In -- College is More Than Classes -- Family Weekend Schedule -- Rowing Revamp from Bow to Stern

Spartan Daily, September 23, 2026, San Jose State University, School Of Journalism And Mass Communications

Spartan Daily, 2026

Volume 167, Issue 14

The Role Of Family Problem-Solving And Neighborhood Social Cohesion On Child Socioemotional Learning Among Families With Low-Income, Nazaret C. Suazo, Alanah C. Claybaugh, Deborah J. Jones

Journal of Applied Research on Children: Informing Policy for Children at Risk

Socioemotional learning (SEL) is linked to a broad range of child outcomes, with income playing an important role in child SEL, yet most work has compared high- and low-income children yielding less understanding of variability in risk and protective factors within low-income families and communities. Building upon theories in the positive youth development literature and public health frameworks exploring social determinants of health, this study explored the role of family problem-solving, neighborhood social cohesion, and neighborhood resources in understanding child SEL within 1097 low-income families of 3- to 5-year-old children who participated in the National Survey of Children’s Health. Using …

Examining The Effect Of Having A Disability On The College Experience, Grace Dudley

James Madison Undergraduate Research Journal (JMURJ)

Among people 25 or older in the United States in 2022, just 21% of individuals with a disability had earned a bachelor’s degree or higher, while 38% of individuals without a disability had earned a bachelor’s degree or higher. Previous research has identified a variety of barriers that students with disabilities may face as they pursue postsecondary education. The purpose of this study was to examine barriers students with disabilities (SWDs) face once they arrive at college in order to investigate how higher education may be made more accessible. Barriers were assessed by surveying SWDs attending James Madison University, a …

Phosphoric Acid-Mediated Regeneration Of Sugarcane Bagasse Cellulose-Rich Fraction For Enzymatic Production Of Water-Soluble Cellulosic Oligomers, Chiou-Yeong Saw, David Agus Setiawan Wibisono, Tsung-Yen Wu, Yung Chang, Chi-Fai Chau

Journal of Food and Drug Analysis

An integrated strategy was developed to promote conversion of a sugarcane bagasse cellulose-rich fraction into water-soluble cellulosic oligomers (WCOs) through phosphoric acid-mediated regeneration and enzymatic hydrolysis. Alkaline pretreatment on sugarcane bagasse powder increased glucan content from 57.6 to 93.4 g/100 g sample and lowered Klason lignin to 6.1 g/100 g sample. Phosphoric acid-mediated regeneration was subsequently capable of reorganizing the structure of cellulose from sugarcane bagasse, resulting in a decrease of crystallinity from 72.9 to 64.0% and introducing cellulose II-like features. The hydration state of regenerated cellulose strongly influenced hydrolysis performance, as the hydrated form showed significantly higher solubilization (810.4 …