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2024

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Public Libraries Encouraged To Meet The Health Information Needs Of Tribal Women In Bangladesh, Lili Luo Jan 2024

Public Libraries Encouraged To Meet The Health Information Needs Of Tribal Women In Bangladesh, Lili Luo

Faculty Research, Scholarly, and Creative Activity

Objective – To investigate public libraries’ existing community engagement practices, explore their willingness to provide health information services to tribal communities in Bangladesh, and examine tribal women’s health information-seeking behavior and interest in obtaining health information from public libraries. Design – A cross-sectional study using online interviews and structured questionnaires. Setting – Public libraries and tribal communities in tribal regions of Bangladesh. Subjects – Public librarians (n=11) and tribal women (n=276) from three tribal districts in Bangladesh (Bandarban, Khagrachari, and Mymensingh). Methods – Interviews were conducted with librarians via Zoom in January 2023. Survey questionnaires were distributed to a convenience …


Multiethnic Elites And The Management Of Tropical Heat In Colonial Malaya, Circa 1870s-1930s, Claire Lowrie, Nicole Tarulevicz, Fiona Williamson, Charmaine H. Lam Jan 2024

Multiethnic Elites And The Management Of Tropical Heat In Colonial Malaya, Circa 1870s-1930s, Claire Lowrie, Nicole Tarulevicz, Fiona Williamson, Charmaine H. Lam

Research Collection College of Integrative Studies

This article considers the responses of multiethnic urban elites to living with tropical heat in colonial Malaya by analysing attitudes towards the meteorological study of temperature, commercial cold storage and hill stations. A transcolonial and transimperial approach is used to illustrate that interest in managing and monitoring temperature was slower to develop in Malaya compared with other tropical colonies. The article also considers how access to methods of ameliorating heat was shaped by colonial hierarchies based on ideas of race and class.


Protocol For A Pilot Clinical Trial Of The Senolytic Drug Combination Dasatinib Plus Quercetin To Mitigate Age-Related Health And Cognitive Decline In Mental Disorders [Version 2; Peer Review: 1 Approved, 2 Approved With Reservations], Abigail Schweiger, Breno Diniz, Ginger Nicol, Julie Schweiger, Andes E Dasklakis-Perez, Eric J Lenze Jan 2024

Protocol For A Pilot Clinical Trial Of The Senolytic Drug Combination Dasatinib Plus Quercetin To Mitigate Age-Related Health And Cognitive Decline In Mental Disorders [Version 2; Peer Review: 1 Approved, 2 Approved With Reservations], Abigail Schweiger, Breno Diniz, Ginger Nicol, Julie Schweiger, Andes E Dasklakis-Perez, Eric J Lenze

2020-Current year OA Pubs

BACKGROUND: Major depressive disorder (MDD) and schizophrenia are linked to accelerated aging leading to reduced lifespan, health span and cognitive decline. Cellular senescence, in which cells lose proliferative capacity and develop a senescence-associated secretory phenotype (SASP), plays a role in this process. Emerging research suggests that the senolytic regimen of dasatinib+quercetin (D+Q) reduces senescent cells, potentially mitigating age-related health and cognitive decline. This pilot study aims to assess the feasibility and safety of D+Q in older adults with schizophrenia, schizoaffective disorder, and treatment-resistant depression (TRD).

METHODS: This single-center study will recruit 30 participants total aged 50 years or older with …


A Scoping Review Of The Impact Of Food Policy Groups On Local Food Systems In High-Income Countries, Stephanie Louise Godrich, Jess Doe, Sarah Goodwin, Laura Alston, Katherine Kent Jan 2024

A Scoping Review Of The Impact Of Food Policy Groups On Local Food Systems In High-Income Countries, Stephanie Louise Godrich, Jess Doe, Sarah Goodwin, Laura Alston, Katherine Kent

Research outputs 2022 to 2026

This scoping review aimed to explore international evidence on the impact of Food Policy Groups (FPGs) on local food systems, in urban and rural regions of high-income countries. Peer-reviewed and grey literature were searched to identify 31 documents published between 2002 and 2022 providing evidence on the impact of FPGs. Activities spanned domains including increasing food equity (e.g. strengthening school meals programs); increasing knowledge and/or demand for healthy food (e.g. food literacy programs with children and adults); increasing food access (e.g. enhancing local food procurement); environmental sustainability (e.g. promoting low-waste food items on café menus); economic development (e.g. ensuring local …


2024 Spring Commencement, Georgia Southern University Jan 2024

2024 Spring Commencement, Georgia Southern University

Commencement Programs

No abstract provided.


2024 Fall Commencement, Georgia Southern University Jan 2024

2024 Fall Commencement, Georgia Southern University

Commencement Programs

No abstract provided.


Study Protocol For A Stepped-Wedge Cluster (Nested) Randomized Controlled Trial Of Antenatal Colostrum Expression (Ace) Instruction In First-Time Mothers: The Ace Study, Cassandra Cuffe, Roslyn Giglia, Matthew N. Cooper, Julie Hill, Desiree Silva, Anita M. Moorhead, Valerie Verhasselt, Joshua R. Lewis, Deborah Ireson, Jill R. Demirci, Talea Cotte, Kathryn Webb, Frances Patey, Therese A. O’Sullivan Jan 2024

Study Protocol For A Stepped-Wedge Cluster (Nested) Randomized Controlled Trial Of Antenatal Colostrum Expression (Ace) Instruction In First-Time Mothers: The Ace Study, Cassandra Cuffe, Roslyn Giglia, Matthew N. Cooper, Julie Hill, Desiree Silva, Anita M. Moorhead, Valerie Verhasselt, Joshua R. Lewis, Deborah Ireson, Jill R. Demirci, Talea Cotte, Kathryn Webb, Frances Patey, Therese A. O’Sullivan

Research outputs 2022 to 2026

Background: Although many mothers initiate breastfeeding, supplementation with human-milk substitutes (formula) during the birth hospitalization is common and has been associated with early breastfeeding cessation. Colostrum hand expressed in the last few weeks before birth, known as antenatal colostrum expression (ACE), can be used instead of human-milk substitutes. However, evidence is lacking on the efficacy of ACE on breastfeeding outcomes and in non-diabetic mothers. Methods and Planned Analysis: This multicenter stepped-wedge cluster (nested) randomized controlled trial aims to recruit 945 nulliparous pregnant individuals. The trial is conducted in two phases. During Phase 1, control group participants are under standard care. …


Is Multidimensional Poverty Associated To Dementia Risk? The Case Of Older Adults In Pakistan, Jean-François Trani, Yiqi Zhu, Soobin Park, Ganesh M Babulal Jan 2024

Is Multidimensional Poverty Associated To Dementia Risk? The Case Of Older Adults In Pakistan, Jean-François Trani, Yiqi Zhu, Soobin Park, Ganesh M Babulal

2020-Current year OA Pubs

BACKGROUND AND OBJECTIVES: Multidimensional poverty is associated with dementia. We aimed at establishing this association in Pakistan.

RESEARCH DESIGN AND METHODS: A cross-sectional study was conducted in Punjab and Sindh, Pakistan, between March 30, 2002, and August 22, 2022, among adults aged 50 and older. Multidimensional poverty measures were composed of 6 dimensions and 15 indicators. Poverty was compared between adults with and without dementia using the Rowland Universal Dementia Assessment Scale, adjusting for sex, age, marital status, and household size. Associations between dementia and poverty were investigated using a multivariate logistic regression model.

RESULTS: We found that 594 (72.7%), …


Community-Based Respiratory Health Measures In Children And Young People With Cerebral Palsy: A Scoping Review, Rachel Knight Lozano, Harriet Shannon, Jonathan Gilby, Sian Goddard, Leanne Turner, Jonathan Marsden Jan 2024

Community-Based Respiratory Health Measures In Children And Young People With Cerebral Palsy: A Scoping Review, Rachel Knight Lozano, Harriet Shannon, Jonathan Gilby, Sian Goddard, Leanne Turner, Jonathan Marsden

School of Health Professions

Aim: To identify, map, and describe outcome measurement domains and instruments used within a community setting to assess respiratory health in children and young people aged 1 to 18 years, diagnosed with cerebral palsy (CP). Method: A scoping review methodology informed structured searches in nine databases, grey literature, and registries, conducted in August 2021 (updated in February 2023). Articles were screened for eligibility by two independent researchers. Any outcome measurement instruments used to assess respiratory health or associated impact were extracted, categorized, and mapped to health and health-related domains of the International Classification of Functioning, Disability, and Health. Results: Seventy-six …


Salivary Biomarkers: The Early Diagnosis Of Alzheimer's Disease, S. Nazir Jan 2024

Salivary Biomarkers: The Early Diagnosis Of Alzheimer's Disease, S. Nazir

School of Engineering, Computing and Mathematics

The precise identification of Alzheimer's disease and other prevalent neurodegenerative diseases remains a difficult issue that requires the development of early detection of the disease and inexpensive biomarkers that can replace the present cerebrospinal fluid and imaging biomarkers. Blood biomarkers, such as amyloid and neurofilament light, have been emphasized as an important and practical tool in a testing or examination procedure thanks to advancements in ultra-sensitive detection techniques. Although saliva is not currently being researched for neurodegenerative diseases, it is an important source of biomarkers that can be used for the identification of diseases and has some advantages over other …


Unlocking The Power Of Ketogenic Diets: Evidence-Based Insights Into Weight Loss, Diabetes, And Beyond, Doreen Ugwu, Ana M. Palacios Jan 2024

Unlocking The Power Of Ketogenic Diets: Evidence-Based Insights Into Weight Loss, Diabetes, And Beyond, Doreen Ugwu, Ana M. Palacios

Eagles Talking About the Public’s Health

No abstract provided.


Beyond Borders: Exploring The Lived Experiences Of International Migrant Women In Nigeria, A Deep Dive Into Healthcare Realities And Utilization, Juliet Nwafor, Rowland Edet, Ezebunwa Nwokoch Jan 2024

Beyond Borders: Exploring The Lived Experiences Of International Migrant Women In Nigeria, A Deep Dive Into Healthcare Realities And Utilization, Juliet Nwafor, Rowland Edet, Ezebunwa Nwokoch

Department of Sociology: Faculty Publications

This study explored access to and utilization of healthcare facilities among migrant women in an urban slum community in Nigeria, focusing on factors influencing healthcare-seeking behaviors and the implications for public health interventions. A qualitative case study-oriented research design was employed, involving in-depth interviews with 21 migrant women of reproductive age and 4 key informant interviews with healthcare workers in the Ayobo community of Lagos State, Nigeria. Data collection occurred from June to September 2018, and thematic analysis was used to interpret the findings. Three main themes emerged: living conditions, pattern of healthcare utilization, and factors influencing accessibility and utilization …


Ice Algae As Supplementary Food Rather Than Major Energy Source For The Barents Sea Zooplankton Community, Doreen Kohlbach, Haakon Hop, Anette Wold, Katrin Schmidt, Lukas Smik, Simon T. Belt, Matthias Woll, Martin Graeve, Lucie Goraguer, Øyvind Foss, Philipp Assmy Jan 2024

Ice Algae As Supplementary Food Rather Than Major Energy Source For The Barents Sea Zooplankton Community, Doreen Kohlbach, Haakon Hop, Anette Wold, Katrin Schmidt, Lukas Smik, Simon T. Belt, Matthias Woll, Martin Graeve, Lucie Goraguer, Øyvind Foss, Philipp Assmy

School of Geography, Earth and Environmental Sciences

The Barents Sea is a hotspot for environmental change due to global warming. These changes impact the structure and functioning of the marine ecosystem year-round, and it is therefore important to gain knowledge on trophic relationships and the energy flow from primary producers, i.e., ice algae (sympagic algae) and phytoplankton (pelagic algae) to consumers over the entire seasonal cycle. By using different lipid components as trophic markers, we provide seasonal coverage of the carbon and food-source composition of five of the most abundant and ecologically important zooplankton taxa inhabiting the Barents Sea: copepods, krill, amphipods, pteropods and chaetognaths. Based on …


Association Of Dietary Adherence And Dietary Quality With Weight Loss Success Among Those Following Low-Carbohydrate And Low-Fat Diets: A Secondary Analysis Of The Dietfits Randomized Clinical Trial, Michelle E. Hauser, Jennifer C. Hartle, Matthew J. Landry, Priya Fielding-Singh, Cynthia W. Shih, Fei Fei Qin, Joseph Rigdon, Christopher D. Gardner Jan 2024

Association Of Dietary Adherence And Dietary Quality With Weight Loss Success Among Those Following Low-Carbohydrate And Low-Fat Diets: A Secondary Analysis Of The Dietfits Randomized Clinical Trial, Michelle E. Hauser, Jennifer C. Hartle, Matthew J. Landry, Priya Fielding-Singh, Cynthia W. Shih, Fei Fei Qin, Joseph Rigdon, Christopher D. Gardner

Faculty Research, Scholarly, and Creative Activity

Background: Eating a high-quality diet or adhering to a given dietary strategy may influence weight loss. However, these 2 factors have not been examined concurrently for those following macronutrient-limiting diets. Objective: To determine whether improvement in dietary quality, change in dietary macronutrient composition, or the combination of these factors is associated with differential weight loss when following a healthy low-carbohydrate (HLC) or healthy low-fat (HLF) diet. Design: Generally healthy adults were randomly assigned to HLC or HLF diets for 12 mo (n = 609) as part of a randomized controlled weight loss study. Participants with complete 24-h dietary recall data …


Smart Agriculture Based On Iot Using Drones: A Survey, Shymaa G. Eladl, Hanaa Y. Zaineldin, Amira Y. Haikal, Mahmoud M. Saafan Jan 2024

Smart Agriculture Based On Iot Using Drones: A Survey, Shymaa G. Eladl, Hanaa Y. Zaineldin, Amira Y. Haikal, Mahmoud M. Saafan

Mansoura Engineering Journal

Researchers have studied the potential of unmanned aerial vehicles (UAVs) for real-time visual data acquisition and processing using potent deep learning (DL) algorithms over the past few decades. In this regard, drone use in smart cities has become one of the most common uses for them in recent years. UAVs and the Internet of Things (IoTs) are two popular technologies being used in smart agriculture that are ushering in a new era of agriculture by replacing traditional farming methods. The combination of drones and IoT has the potential to drastically change our lives through real-time data collection and analysis that …


Establishing A Quantitative Assessment Tool For Biophilia In Healthcare Facilities, Sara Moustafa Fouda, Mohanad Ali Fouda Jan 2024

Establishing A Quantitative Assessment Tool For Biophilia In Healthcare Facilities, Sara Moustafa Fouda, Mohanad Ali Fouda

Mansoura Engineering Journal

This study aims at developing a novel assessment tool that can quantitatively evaluate the level of biophilia integration in healthcare facilities. The developed assessment tool helps to address the difficulty of biophilia quantification in the built environment due to the broad nature of the biophilia concept. The methodological approach for the tool depends on employing biophilic design patterns as a basis for biophilia, where these patterns are correlated to a group of biophilia-related features of the WELL Building Standard. This correlation is attained through a list of Integrated Design Guidelines (IDGs) that is proposed to act as an intermediate ground …


The Early Prevention Of Diabetic Foot Ulcers, Aruodo Ukpai Jan 2024

The Early Prevention Of Diabetic Foot Ulcers, Aruodo Ukpai

Doctor of Nursing Practice Projects

Frequent and proper foot exams and foot care are fundamental in decreasing the incidence and morbidity of diabetic foot ulcers, yet many patients are still not screened at appointments or educated on the importance of foot exams. This research planned to address the lack of foot care education and foot assessments amongst patients with Type 2 diabetes. Past research done on this focused on providing education to diabetic patients either at home or in a setting where patients can come and receive the education. To our knowledge, no research has been done on the use of video teaching to provide …


Benefits Of Patient-Centered Education For Type 2 Diabetes Mellitus, Paige Bortnick Jan 2024

Benefits Of Patient-Centered Education For Type 2 Diabetes Mellitus, Paige Bortnick

Doctor of Nursing Practice Projects

Type 2 diabetes is a chronic, lifelong illness that affects millions of individuals in the United States. The rate of diabetes has doubled over the last 20 years in America and has climbed to be the seventh leading cause of death amongst Americans. The purpose of this project was to determine if participants in the target community demonstrated increased knowledge and awareness of diabetes after receiving education. A pre-intervention and post-intervention survey was given to determine if the education was effective. Data collected revealed an increased awareness and knowledge regarding the prevalence of type 2 diabetes, lifestyle, and diet modification.


Community Education: Impact On Earlier Recognition Of Stroke, Lauren Kahn Jan 2024

Community Education: Impact On Earlier Recognition Of Stroke, Lauren Kahn

Doctor of Nursing Practice Projects

Cerebrovascular disease was identified as the fourth leading cause of death in Cleveland County, North Carolina from 2014 to 2018 (Cleveland County Public Health Center, 2020). Community education was identified as a potential solution to decreasing the number of community members affected by cerebrovascular disease and resulting death and disability. Five community classes were taught with 97 participants. Pre-, post-, and 1-week post-class surveys were distributed to assess baseline knowledge, knowledge gain, and knowledge retention, with 74 pre-class, 72 post-class, and 28 1-week post-class surveys returned. Of these surveys, after exclusionary criteria were used, 40 pre-class, 53 post-class, and 22 …


My World's On Fire, How 'Bout Yours? An Investigation Of How Privilege Fosters And Maintains Climate Denial, Morgan A. Chester Jan 2024

My World's On Fire, How 'Bout Yours? An Investigation Of How Privilege Fosters And Maintains Climate Denial, Morgan A. Chester

Antioch University Dissertations & Theses

The present study investigates the phenomenon of climate denial through a new theoretical framework of privilege. The analysis utilizes a feminist orientation that builds on a historical interpretation through the lens of colonialism. Through the dissection of current multidisciplinary understandings of climate denial and new concepts discovered in the review of academic literature and popular media, a compilation of theory, relationship, and connection is made. Systems of power and privilege are examined and connected to the mechanisms and maintenance of climate denial. The resulting analysis illuminates that settler colonialism, supported by connected ideologies of White supremacy, ableism, and patriarchy inform …


From The Ground Up: A Complex Systems Approach To Climate Change Adaptation In Agriculture, Karen Buchsbaum Jan 2024

From The Ground Up: A Complex Systems Approach To Climate Change Adaptation In Agriculture, Karen Buchsbaum

Antioch University Dissertations & Theses

Climate change presents an unprecedented challenge to global agriculture and food security. Small farms are especially vulnerable to the local impacts of large-scale drivers of change. Effective adaptation in agriculture requires working across scales, and geographic, political, and disciplinary boundaries to address barriers. I use elements of case study, agent-based modeling and serious games, to design a model of farmer decision-making using the sociocognitive framework of climate change adaptation. I examine how adaptation functions as a process, how complex dynamics influence farmer behavior, and how individual decisions influence collective behavior in response to climate change. This novel approach to adaptation …


The Benefits Of Prenatal Education Via Virtual And Mobile Applications Before, During, And After Pregnancy: A Quality Improvement Project, Lindsay Farland Jan 2024

The Benefits Of Prenatal Education Via Virtual And Mobile Applications Before, During, And After Pregnancy: A Quality Improvement Project, Lindsay Farland

Master's Theses and Capstones

Background: The advancements of technology has led to a substantial increase in the use of pregnancy applications among expecting parents. Studies indicate that a majority of pregnant individuals utilize virtual education platforms for various purposes, including accessing information on nutrition, exercise, baby development, and pregnancy symptoms. Despite the potential benefits, participation in these platforms remains low, emphasizing a need for enhanced resources and engagement strategies. Research shows that engagement with antenatal education through mobile applications can lead to improved maternal and fetal outcomes, such as reduced rates of caesarean births and fewer complications related to hypertension or preeclampsia.

Methods: …


Implementing A Nurse-Driven Protocol To Reduce Routine Gastric Residual Monitoring: A Quality Improvement Project, Alondra N. Abreu Carlo Jan 2024

Implementing A Nurse-Driven Protocol To Reduce Routine Gastric Residual Monitoring: A Quality Improvement Project, Alondra N. Abreu Carlo

Master's Theses and Capstones

The American Society for Enteral and Parenteral Nutrition (ASPEN) and the Society for Critical Care Medicine (SCCM) updated the Adult Patient Enteral Nutrition Guidelines in 2016. These updates included discontinuing routine gastric residual monitoring due to its contribution to poor patient outcomes and mentioning the lack of evidence proving its relevance to gastric motility. Per ASPEN and SCCM, best practice suggests monitoring patients for intolerance symptoms and then checking gastric residual volume (GRV) if symptoms are present. If the GRV is greater than 500ml and intolerance symptoms are present, the recommendation is to perform further assessment, potentially leading to stopping …


Educational Interventions To Improve Icu Nurses’ Knowledge And Confidence Related To Pressure Injuries: A Quality Improvement Initiative, Benjamin R. Maltais Jan 2024

Educational Interventions To Improve Icu Nurses’ Knowledge And Confidence Related To Pressure Injuries: A Quality Improvement Initiative, Benjamin R. Maltais

Master's Theses and Capstones

Background: The prevalence of pressure injuries (PI) in critical care is highest amongst inpatient units, and are associated with significant complications, decreased quality of life, increased cost of hospitalization, and poor patient care (Agency for Healthcare Research and Quality, 2019; Cox et al., 2022; Gorecki et al., 2014; Mervis & Phillips, 2019). Similarly, many PI are considered to be avoidable (Pittman et al., 2019). Despite an increase in focus on PI awareness and prevention, there still remains a challenge for patients in critical care units. In addition, research has indicated that nurses’ lack of basic knowledge of PI (risk assessment, …


Uropathogenic Escherichia Coli Wield Enterobactin-Derived Catabolites As Siderophores, Zongsen Zou, John I Robinson, Lindsey K Steinberg, Jeffrey P Henderson Jan 2024

Uropathogenic Escherichia Coli Wield Enterobactin-Derived Catabolites As Siderophores, Zongsen Zou, John I Robinson, Lindsey K Steinberg, Jeffrey P Henderson

2020-Current year OA Pubs

Uropathogenic Escherichia coli (UPEC) secrete multiple siderophore types to scavenge extracellular iron(III) ions during clinical urinary tract infections, despite the metabolic costs of biosynthesis. Here, we find the siderophore enterobactin (Ent) and its related products to be prominent components of the iron-responsive extracellular metabolome of a model UPEC strain. Using defined Ent biosynthesis and import mutants, we identify lower molecular weight dimeric exometabolites as products of incomplete siderophore catabolism, rather than prematurely released biosynthetic intermediates. In E. coli, iron acquisition from iron(III)-Ent complexes requires intracellular esterases that hydrolyze the siderophore. Although UPEC are equipped to consume the products of completely …


Challenging The Criminalization Of Undocumented Drivers Through A Health-Justice Framework, Jason A. Cade Jan 2024

Challenging The Criminalization Of Undocumented Drivers Through A Health-Justice Framework, Jason A. Cade

Scholarly Works

States increasingly use driver’s license laws to further policy objectives unrelated to road safety. This symposium contribution employs a health justice lens to focus on one manifestation of this trend—state schemes that prohibit noncitizen residents from accessing driver’s licenses and then impose criminal sanctions for driving without authorization. Status-based no-license laws not only facilitate legally questionable enforcement of local immigration priorities but also impose structural inequities with long-term health consequences for immigrants and their family members, including US citizen children. Safe, reliable transportation is a significant social determinant of health for individuals, families, and communities. Applying a health justice lens …


2024 Belknap County 4-H Presents, Karen Deighan Jan 2024

2024 Belknap County 4-H Presents, Karen Deighan

UNH Cooperative Extension

No abstract provided.


2023 Health & Well-Being Team Highlights, Amy Hollar, Kendra Lewis, Michael C. Young Jan 2024

2023 Health & Well-Being Team Highlights, Amy Hollar, Kendra Lewis, Michael C. Young

UNH Cooperative Extension

No abstract provided.


North Haverhill Fair 4-H Exhibit Hall Information Packet - 2024, Extension Jan 2024

North Haverhill Fair 4-H Exhibit Hall Information Packet - 2024, Extension

UNH Cooperative Extension

No abstract provided.


Posttransplantation Late Complications Increase Over Time For Patients With Scid: A Primary Immune Deficiency Treatment Consortium (Pidtc) Landmark Study, Hesham Eissa, Monica S Thakar, Ami J Shah, Brent R Logan, Linda M Griffith, Huaying Dong, Roberta E Parrott, Richard J O'Reilly, Jasmeen Dara, Neena Kapoor, Lisa Forbes Satter, Sharat Chandra, Malika Kapadia, Shanmuganathan Chandrakasan, Alan Knutsen, Soma C Jyonouchi, Lyndsay Molinari, Ahmad Rayes, Christen L Ebens, Pierre Teira, Blachy J Dávila Saldaña, Lauri M Burroughs, Sonali Chaudhury, Deepak Chellapandian, Alfred P Gillio, Fredrick Goldman, Harry L Malech, Kenneth Desantes, Geoff D E Cuvelier, Jacob Rozmus, Ralph Quinones, Lolie C Yu, Larisa Broglie, Victor Aquino, Evan Shereck, Theodore B Moore, Mark T Vander Lugt, Talal I Mousallem, Joeseph H Oved, Morna Dorsey, Hisham Abdel-Azim, Caridad Martinez, Jacob H Bleesing, Susan Prockop, Donald B Kohn, Jeffrey J Bednarski, Jennifer Leiding, Rebecca A Marsh, Troy Torgerson, Luigi D Notarangelo, Sung-Yun Pai, Michael A Pulsipher, Jennifer M Puck, Christopher C Dvorak, Elie Haddad, Rebecca H Buckley, Morton J Cowan, Jennifer Heimall Jan 2024

Posttransplantation Late Complications Increase Over Time For Patients With Scid: A Primary Immune Deficiency Treatment Consortium (Pidtc) Landmark Study, Hesham Eissa, Monica S Thakar, Ami J Shah, Brent R Logan, Linda M Griffith, Huaying Dong, Roberta E Parrott, Richard J O'Reilly, Jasmeen Dara, Neena Kapoor, Lisa Forbes Satter, Sharat Chandra, Malika Kapadia, Shanmuganathan Chandrakasan, Alan Knutsen, Soma C Jyonouchi, Lyndsay Molinari, Ahmad Rayes, Christen L Ebens, Pierre Teira, Blachy J Dávila Saldaña, Lauri M Burroughs, Sonali Chaudhury, Deepak Chellapandian, Alfred P Gillio, Fredrick Goldman, Harry L Malech, Kenneth Desantes, Geoff D E Cuvelier, Jacob Rozmus, Ralph Quinones, Lolie C Yu, Larisa Broglie, Victor Aquino, Evan Shereck, Theodore B Moore, Mark T Vander Lugt, Talal I Mousallem, Joeseph H Oved, Morna Dorsey, Hisham Abdel-Azim, Caridad Martinez, Jacob H Bleesing, Susan Prockop, Donald B Kohn, Jeffrey J Bednarski, Jennifer Leiding, Rebecca A Marsh, Troy Torgerson, Luigi D Notarangelo, Sung-Yun Pai, Michael A Pulsipher, Jennifer M Puck, Christopher C Dvorak, Elie Haddad, Rebecca H Buckley, Morton J Cowan, Jennifer Heimall

Faculty, Staff and Students Publications

Background: The Primary Immune Deficiency Treatment Consortium (PIDTC) enrolled children in the United States and Canada onto a retrospective multicenter natural history study of hematopoietic cell transplantation (HCT).

Objective: We investigated outcomes of HCT for severe combined immunodeficiency (SCID).

Methods: We evaluated the chronic and late effects (CLE) after HCT for SCID in 399 patients transplanted from 1982 to 2012 at 32 PIDTC centers. Eligibility criteria included survival to at least 2 years after HCT without need for subsequent cellular therapy. CLE were defined as either conditions present at any time before 2 years from HCT that remained unresolved (chronic), …