Digital Commons Network^™

An Exploration Of The Genetics Of The Mutant Huntingtin (Mhtt) Gene In A Cohort Of Patients With Chorea From Different Ethnic Groups In Sub-Saharan Africa, Mendi J. Muthinja, Carlos Othon Guelngar, Maouly Fall, Fatumah Jama, Huda Aldeen Shuja, Jamila Nambafu, Daniel Gams Massi, Oluwadamilola Ojo, Juzar Hooker, Dilraj Sokhi

Internal Medicine, East Africa

Background: Africans are underrepresented in Huntington's disease (HD) research. A European ancestor was postulated to have introduced the mutant Huntingtin (mHtt) gene to the continent; however, recent work has shown the existence of a unique Htt haplotype in South-Africa specific to indigenous Africans.

Objective: We aimed to investigate the CAG trinucleotide repeats expansion in the Htt gene in a geographically diverse cohort of patients with chorea and unaffected controls from sub-Saharan Africa.

Methods: We evaluated 99 participants: 43 patients with chorea, 21 asymptomatic first-degree relatives of subjects with chorea, and 35 healthy controls for the presence of the mHtt. Participants …

A Compendium Of Cross-Culturally Valid Intimate Partner Violence Assessment Items For North American Spanish Speakers, Alberto D. Torres-Aragón

Undergraduate Honors Theses

Intimate partner violence (IPV) is physical, psychological, or sexual abuse by a current or former romantic partner. The long- and short-term consequences can lead to severe repercussions. To prevent these consequences of IPV, we need to screen for it and assess it. Across cultures, IPV is present and should be assessed regardless of linguistic boundaries. Spanish is the most widely used language in the U.S. other than English; therefore, assessment instruments that can reliably capture IPV in Spanish are necessary. Although Spanish-language IPV instruments are available, they may be challenging to understand for Spanish speakers because of linguistic differences. In …

Fatally Flawed: D.D. Kosambi’S Grave Missteps In The Study Of Indian History, Vivek K. Rallabandi

Student Publications

D.D. Kosambi, a multifaceted historian in late colonial and post-colonial India, has been acclaimed for his scholarship. However, this paper argues that Kosambi's Marxist ideology caused him to interpret Indian history in a way that conformed with his ideological presuppositions. Such an approach, this paper posits, led to critical historical inaccuracies in Kosambi's work.

Exploring Barriers To Ophthalmic Clinical Research Care Delivery, James William Green

Walden Dissertations and Doctoral Studies

No abstract provided.

Implementation Of A Bilingual Feeding Program For Hispanic Children With Autism Spectrum Disorder, Sarah Aguilar

Capstone Projects

Feeding is an important occupation that contributes to a child’s physical, emotional, and social development and is also influenced by cultural and environmental factors, (Korth & Maune, 2020). In individuals with developmental delays, specifically autism spectrum disorder (ASD), feeding difficulties have been reported in as many as 75% of children (Nygren et al., 2021). These difficulties often result in increased feelings of anxiety experienced by the child and caregiver. Limited information exists on the impact of these on minority populations, such as Spanish speaking families that face many challenges when accessing healthcare services like language and cultural barriers. Similarly, group …

Intersectionality Of Social Identity, Trauma, And Education: A First-Generation College Student's Reflective Journey, Richard De La Garza

Student RSCA

This reflective paper explores the intersectionality of social identity, trauma, and education through the lens of a first-generation college student (FGCS) who is a neurodivergent Army veteran. I share my personal journey and experiences, highlighting marginalized communities’ challenges in the edu- cation system. I delve into the impact of cultural invasion, the transmission of trauma across generations, and the importance of critical consciousness in addressing educational inequality. I also discuss the role of spatial thinking and language in shaping learning experiences. I emphasize the need for cultural awareness, inclusivity, and equity in educational spaces and high- light the transformative power …

Ebs 701: Issues In Bilingualism, Lingyu Li

Open Educational Resources

This introductory course addresses the nature of bilingualism as a societal and individual phenomenon. It will explore the history and background of bilingual education, policies, approaches, and theories of education for immigrant, bilingual, and language minority students. It will also consider the social, cultural, and economic context surrounding the education of bilingual students with disabilities and issues surrounding the aforementioned topics. (15 fieldwork hours required.)

The Conflict Of Orthodox Narratives In Ukrainian Society: Searching For A Methodology To Analyze The Religious Crisis, Hennadii Khrystokin, Vasyl Lozovytskyi

Occasional Papers on Religion in Eastern Europe

As a result of the study, we were able to establish that the crisis of Ukrainian Orthodoxy is a conflict that has a clear linguistic and symbolic dimension. In order to analyze the conflict between Orthodox actors, it is advisable to use a critical-reflective methodology that allows for the analysis of both theological language and the tools that form this language. We have been able to establish that the Orthodox crisis in Ukraine reflects a conflict between the religious narratives and practices of the UOC and the OCU, the root cause of which is an internal crisis between the narratives …

An Efficient Neutrosophic Type-2 Model For Selecting Optimal Internet Of Things (Iot) Service Provider: Analysis And Applications, Ibrahim Alrashdi

Neutrosophic Sets and Systems

The Internet of Things, or IoT, is a rapidly expanding technology, and one of its most important application areas is sustainable transportation. Choosing the right IoT service provider is a complex process that is considered a multi-criteria decision issue. The multi-criteria decision-making (MCDM) methodology deals with massive criteria. This study proposed an MCDM methodology for selecting the best IoT service provider under different sustainable criteria. The Multi-Objective Optimization Ratio Analysis (MOORA) method is an MCDM methodology used to rank the alternatives. The MOORA method is integrated with a type 2 neutrosophic set to deal with uncertain information. The proposed MCDM …

Exploring Neutrosophic Linear Programming In Advanced Fuzzy Contexts, Shubham Kumar Tripathi, Arindam Dey, Said Broumi, Ranjan Kumar

Neutrosophic Sets and Systems

A neutrosophic set is a mathematical framework that extends fuzzy and intuitionistic sets to han dle indeterminate or contradictory information using three components: truth, falsity, and indeterminacy membership degrees which deal with handling indeterminate, imprecise, and uncertain data, while Extended Fuzzy Theory extends the standard fuzzy set theory to manage more intricate membership degrees. The pri mary objective of this review is to thoroughly investigate and summarize the existing literature on trapezoidal neutrosophic environments, particularly focusing on aspects such as the NFMOLP Problems in SVTpN envi ronments. Ultimately, this comprehensive review article aims to enhance the understanding of the potential …

Logarithmic Similarity Measure Of Neutrosophic Z-Number Sets For Undergraduate Teaching Quality Evaluation, Wen-Ping Chen, Yi-Ming Fang, Wen-Hua Cui

Neutrosophic Sets and Systems

In practical decision-making problems, the different reliability levels of decision-makers in their evaluation information are usually ignored by most existing decision-making methods. Then, a neutrosophic Z-number (NZN) is a powerful model for simultaneously describing the restraint and associated reliability of evaluation information in view of truth, indeterminacy, and falsity Z-numbers. This paper first proposed a logarithmic similarity measure (LSM) of NZN sets, which is more flexible and can change its measure result by adjusting the exponential parameters of the restraint and reliability. Then, a multi-attribute decision-making approach is developed based on the presented LSM of NZN sets, and its applicability …

Deep Learning To Predict Rapid Progression Of Alzheimer's Disease From Pooled Clinical Trials: A Retrospective Study, Xiaotian Ma, Madison Shyer, Kristofer Harris, Dulin Wang, Yu-Chun Hsu, Christine Farrell, Nathan Goodwin, Sahar Anjum, Avram S Bukhbinder, Sarah Dean, Tanveer Khan, David Hunter, Paul E Schulz, Xiaoqian Jiang, Yejin Kim

Faculty, Staff and Student Publications

The rate of progression of Alzheimer's disease (AD) differs dramatically between patients. Identifying the most is critical because when their numbers differ between treated and control groups, it distorts the outcome, making it impossible to tell whether the treatment was beneficial. Much recent effort, then, has gone into identifying RPs. We pooled de-identified placebo-arm data of three randomized controlled trials (RCTs), EXPEDITION, EXPEDITION 2, and EXPEDITION 3, provided by Eli Lilly and Company. After processing, the data included 1603 mild-to-moderate AD patients with 80 weeks of longitudinal observations on neurocognitive health, brain volumes, and amyloid-beta (Aβ) levels. RPs were defined …

Contributions Of Barad's New Materialism To Well-Being Research, M. Isidora Bilbao-Nieva, Alejandra Meyer

The Qualitative Report

In this article, we discuss the contributions that Karen Barad's theorizations can make to the study of well-being, particularly their ontoepistemological framework, “agential realism,” that emphasizes the inseparability of matter, ethics, and knowledge, as the relational entanglements of agencies. We use these ideas to imagine well-being as differential materializations, entanglements of human, and the non-human agencies that “intra-act” with each other and are inseparable from how we know about them and our responsibilities in their reconfigurations. From this perspective, we see well-being as a phenomenon, underpinning its dynamism and processuality. Analyzing an interview fragment, we exemplify how Barad's theorizations can …

Students’ Experiences When Using Real-Time Automated Captions And Subtitles In Live Online Presentations: A Phenomenological Study, Anymir Orellana Ed.D., Elda Kanzki-Veloso Ph.D., Georgina Arguello Ed.D., Katarzyna Wojnas

The Qualitative Report

According to the Universal Design for Learning (UDL) framework, as a text-based alternative to auditory information in videos or presentations, captions can make the content equally accessible, and multilingual subtitles can promote a cross-linguistic understanding of the content. We conducted a phenomenological study to understand the common meaning of the participants’ experiences when using real-time automated captions/subtitles during live online class presentations. Twenty-four remote student participants were placed in three study groups. All participants were fluent in spoken and written English, eight could read in one or more additional languages, and none had a hearing disability. We used Microsoft PowerPoint …

Juggling Academic Practice And Care: Collaborative Autoethnography Within A Basque University Research Group, Asunción Martínez-Arbelaiz, Aingeru Gutierrez-Cabello, Estibaliz Aberasturi-Apraiz, Jose M. Correa-Gorospe

The Qualitative Report

Many university scholars, including the authors of this article, acknowledge that they feel like they are riding an emotional roller coaster with academic success, as well as many project failures. Except for our PhD thesis, many of us complete our research tasks in relatively established research groups. However, little research has examined the potential these groups might have to mitigate feelings of academic isolation. To fill in this gap, we designed two methodological steps. First, we adopted the Woolfian metaphor of a room of our own, where we composed individual vignettes regarding our feelings of isolation. We read each other's …

Foundation Myths And Their Societal Impact: The American Dream As A Case In Point, Justin Pilgreen

Dartmouth College Master’s Theses

This thesis ventures into the intricate realm of foundation myths and their impact on shaping national identities, with an emphasis on the American Dream as a central, master myth within the American narrative framework. Foundation myths serve as the bedrock of a nation's identity, crystallizing its values, aspirations, and collective memory. The American Dream transcends its role as a mere aspirational ideal to act as a powerful orchestrator of a myriad of sub-myths that collectively forge the American ethos.

By engaging with theoretical perspectives on myth's role in national identity formation and the crafting of a "usable past," this thesis …

0887: Gwenyth E. Hood Collection, 1889-2023, Marshall University Special Collections

Guides to Manuscript Collections

Gwenyth Elise Hood was born on December 10, 1955, to Thomas Arthur Hood and Marion Louise Snee Hood in White Plains, NY, but moved with her family to Brandon, Vermont at the age of seven. She developed a love of reading and writing at an early age, discovering some favorite authors—Rudyard Kipling, Shakespeare, and J.R.R. Tolkien—at roughly the same time, in early adolescence. Then came Dante. Dante drew her to learn Latin and Italian; she had already started on French due to family heritage and the availability of the language in High School. In 1979 she won a University of …

Experts-Driven Design: A Framework For Measuring Social Influence In Online Social Networks, Shyamala N. Chalakudi, Dildar Hussain Dr., Gnana Bharathy Dr, Dakshinamurthy Kolluru Dr

AMTP Proceedings 2024

In our interconnected and ever-changing social landscape, influence is pivotal in molding individuals’ decisions, perspectives, and behaviors. Measuring Social Influence (SI) in Online Social Networks (OSNs) faces significant gaps, notably needing more integration with human behaviors. Our literature review has unveiled twelve psychological theories rooted in human behavior that are fundamental for assessing SI in OSNs. We have further elucidated how human behaviors interact in shaping the influence potential of social media users through exploratory interviews with experts from consulting, industry, and academia. Our study culminated in developing a novel framework designed to encompass the intricacies that not only nurture …

More Than Representation Heartstopper: A Multimodal Critical Discourse Analysis, Tracyann Josephine Harmer

Communication & Theatre Arts Theses

This thesis is a multimodal critical discourse analysis of Netflix’s Heartstopper, written with the goal of understanding its methods of representation and queer world creation. Through analysis of the ideology of heteronormativity as it relates to masculinity, internalized homophobia, homophobia, and mental health, I expand upon the significance of queer representation for queer audiences, heterosexual audiences, and producers of queer media. Through a nuanced analysis of these themes, I display how and why Heartstopper has had enormous success and expand upon the cultural phenomena surrounding this media. Finally, this thesis places these nuanced analyses into the real-world reaction to …

The Experiences Of Multilingual Learning-Focused School Counselors: A Phenomenological Investigation, Chelsea Jo Hilliard

Counseling & Human Services Theses & Dissertations

Equity in education has become increasingly prioritized, due to the growing mainstream recognition of the inequitable practices that historically have and presently continue to exist in K-12 education. With the K-12 student population diversity continuously increasing in areas such as abilities, race/ethnicities, socioeconomic status, languages, immigration status, and more, ensuring equitable access to education is vital. One such unique student group needing equitable access to education are multilingual learners or MLL. Located within schools, school counselors are uniquely positioned to equitably serve MLL students. Overall, while the research on school counselors serving MLL students (at the pre-service and practice level) …

From Predominantly White To Hispanic-Serving: Latinx Student Experiences On A Campus In Transition, Gabriel M. Velez, Jacqueline Black, Saúl López, Kimberly D'Anna-Hernandez

College of Education Faculty Research and Publications

This study utilized focus groups with Latinx students at a private, Midwestern university to explore the complexities inherent in the process of becoming a Hispanic-Serving Institution (HSI). The purpose of the study was: (a) to better understand Latinx students’ experiences at an “emerging” HSI, and (b) to understand how students understand an institutional journey toward the HSI designation. Findings point toward the value in exploring the Latinx student experience and perspective on HSI initiatives.

Resumen

Este estudio utilizó grupos foco con estudiantes latinx en una Universidad privada, del medio-oeste en EEUU para explorar las complejidades inherentes en el proceso de …

Intelligent Tutoring System Ontology, Wael Mohamed Hassan

Theses

The integration of pedagogical rules into Intelligent Tutoring Systems (ITS) using semantic web technologies, particularly the Web Ontology Language (OWL), holds great promise for enhancing the capabilities of these systems. However, a significant challenge arises from the labor-intensive process of manually constructing ontologies, which can consume valuable time and resources. While ontologies offer numerous advantages, including robust knowledge inference and scalability, the limitations of manual ontology creation are evident in terms of time and flexibility. Therefore, the primary objective of this research is to develop an efficient and automated solution that harnesses the benefits of ontologies while reducing the time …

Transformer-Based Deep Learning Model For Sign Language Recognition, Ganzorig Batnasan

Theses

Sign language recognition research aims to develop systems and tools that can interpret and translate sign language into text or spoken language. During the past two decades, the challenges faced in this domain are multifaceted. The first and foremost challenge is the complexity of sign language, which includes intricate hand gestures, facial expressions, and body movements. Recognizing and interpreting these components accurately is challenging. The second challenge is variability among different regions and communities, leading to variations in signs and gestures. This variability poses a challenge for developing universal recognition systems.
Limited data is another challenge which makes it difficult …

School Leadership For The Practice Of Inclusive Education In Elementary Schools In The United Arab Emirates, Aysha Saeed Al Nuaimi

Dissertations

The number of students with disabilities in regular classrooms is increasing. In 2020, the United Arab Emirates (UAE) introduced a new policy with the goal of promoting inclusive education in all public schools. Although the UAE government is committed to the education of children with disabilities, the role of school leaders is vital to the successful implementation of inclusive education in schools. While school leaders have been found to be the main agents in steering inclusive practices, their contribution to practices in schools in the UAE context remains empirically unresearched. The objective of this study was to explore elementary school …

Investigating Parental Roles In Developing Preschool-Aged Children’S Emergent Literacy In English, Their Second Language, Through Storybook Reading In A Sample Of Kuwaiti Homes, Fajr M. Alkouz

Dissertations

Using a convergent mixed methods design, this study explored home emergent literacy environments actualized by six mothers of young preschool-aged children living in Kuwait. It investigated the role of these Kuwaiti mothers in developing their bilingual preschool-aged children’s print knowledge, oral language, and phonological awareness, as three areas associated with Emergent Literacy (EL). In particular, the study explored the influence of parental storybook reading on the development of bilingual children’s EL skills in English, their Second Language (L2). Employing purposive sampling, this case study obtained statistical quantitative results from parents who responded to a questionnaire about their home literacy experiences …

Prevalence And Risk Factors Of Hikikomori In Young Adults In The Middle East, Harshil Paresh Shah

Theses

Hikikomori, a form of severe social withdrawal that can occur without the presence of any other psychological disorder, was once thought to be a Japanese culture-bound phenomena. However, studies have emerged from several parts of the world showing that this may be a global issue. Extant literature suggests associations between hikikomori and behavioral addictions such as gaming addiction and Problematic Social Media Use (PSMU). Since there is a relative paucity of research examining this phenomenon in the Middle Eastern context, this study aimed to determine the prevalence and risk factors of hikikomori in young adults of the Middle East. It …

Advancing The Decadal Plan For The Science Of Nutrition: Progressing A Framework For Implementation, Helen Truby, Margaret Allman-Farinelli, Eleanor J. Beck, Emma L. Beckett, Catherine Bondonno, Aimee L. Dordevic, Katherine M. Livingstone, Jane Willcox, Shelley A. Wilkinson

Research outputs 2022 to 2026

Aims: In 2019, the Australian Academy of Science in collaboration with the nutrition community published the decadal plan for the science of nutrition. This article aims to review progress towards each of its pillar goals (societal determinants, nutrition mechanisms, precision and personalised nutrition, and education and training) and two enabling platforms (a national data capability and a trusted voice for nutrition science), prioritise actions, and conceptualise program logic implementation models. This process also brought together public health nutrition researchers to reflect on societal determinants of health, and advise how the next 5 years of the decadal plan could reflect contemporary …

The Legal Imitation Game: Generative Ai’S Incompatibility With Clinical Legal Education, Jake Karr, Jason Schultz

Fordham Law Review

In this Essay, we briefly describe key aspects of [generative artificial intelligence] that are particularly relevant to, and raise particular risks for, its potential use by lawyers and law students. We then identify three foundational goals of clinical legal education that provide useful frameworks for evaluating technological tools like GenAI: (1) practice readiness, (2) justice readiness, and (3) client-centered lawyering. First is “practice readiness,” which is about ensuring that students have the baseline abilities, knowledge, and skills to practice law upon graduation. Second is “justice readiness,” a concept proposed by Professor Jane Aiken, which is about teaching law students to …

Chatgpt, Large Language Models, And Law, Harry Surden

Fordham Law Review

This Essay explores Artificial Intelligence (AI) Large Language Models (LLMs) like ChatGPT/GPT-4, detailing the advances and challenges in applying AI to law. It first explains how these AI technologies work at an understandable level. It then examines the significant evolution of LLMs since 2022 and their improved capabilities in understanding and generating complex documents, such as legal texts. Finally, this Essay discusses the limitations of these technologies, offering a balanced view of their potential role in legal work.

If We Could Talk To The Animals, How Should We Discuss Their Legal Rights?, Andrew W. Torrance, Bill Tomlinson

Fordham Law Review

The intricate tapestry of animal communication has long fascinated humanity, with the sophisticated linguistics of cetaceans holding a special place of intrigue due to the cetaceans’ significant brain size and apparent intelligence. This Essay explores the legal implications of the recent advancements in artificial intelligence (AI), specifically machine learning and neural networks, that have made significant strides in deciphering sperm whale (Physeter macrocephalus) communication. We view the ability of a being to communicate as one—but not the only—potential pathway to qualify for legal rights. As such, we investigate the possibility that the ability to communicate should trigger legal …