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A Rare Presentation Of Erysipelothrix Rhusiopathiae Endocarditis With Acute Heart Failure, Maryam Barkhordarian, Mark Grijalva, James Liu, Muhammad Yasir, Abraham Lo

Journal of Community Hospital Internal Medicine Perspectives

Erysipelothrix rhusiopathiae is an occupation-related infection that can be found in farm animals or marine life. This infection can present with a spectrum of infection ranging from local cellulitis to aortic endocarditis. Developing endocarditis is rare from this organism with only a few case reports in the literature. We presented a case of Erysipelothrix rhusiopathiae bacteremia that led to aortic valve endocarditis with a Gerbode defect within the mitral valve complicated with an acute exacerbation of congestive heart failure, necessitating emergent valve replacement surgery, with eventual permanent pacemaker due to complete heart block. We intend to highlight some unusual characteristics …

Rare Case Of Mycobacterium Avium Complex Peritonitis In A Patient With Multiple Myeloma Undergoing Peritoneal Dialysis, Sacide S. Ozgur, Nida Ansari, Dhruv Patel, Ryan Rahman, Raymond Shih

Journal of Community Hospital Internal Medicine Perspectives

Mycobacterium avium complex (MAC) infections can present as a variety of severe diseases. While it has a predilection for immunocompromised patients such as those with Human immunodeficiency virus (HIV), it can also affect immunocompetent patients as well. One of the rare yet severe diseases that MAC infections can present is MAC peritonitis. Often hard to distinguish from other causes of peritonitis, high clinical suspicion should be maintained for those who are susceptible. Here we present an 85-year-old female with a past medical history of end-stage renal disease on peritoneal dialysis who presented with nausea and vomiting. She was found to …

A Rare Case Of Brodie’S Abscess In The Tibial Diaphysis Masquerading As A Vaso-Occlusive Sickle Crisis, Shefali Amin, Manish Shrestha, Suril Amin, Sahil Amin, Katherine Dipastina

Journal of Community Hospital Internal Medicine Perspectives

We present the case of a 19-year-old male with a history of sickle cell cell anemia who presented to the hospital with worsening lower extremity pain. Given his acute presentation and history of recurrent pain crises, he was admitted to the hospital for management of a suspected acute pain crisis. However, due to continued pain, imaging was obtained which revealed a different diagnosis for the cause of his symptoms. MRI of the left lower leg revealed heterogenous T1 and T2 hyperintense signals within the proximal tibial diaphysis measuring 6.6 x 1.6 x 2.2 cm with a thick rim of peripheral …

Reactive Arthritis After Mpox Vaccination, Indira Acharya, Lanaya Williams Smith, Chandralekha Banerjee, Lyn M. Camire, Radhika Vij

Journal of Community Hospital Internal Medicine Perspectives

Autoimmune inflammatory reaction after vaccination is a rare clinical entity. Reactive arthritis has been described after various vaccinations, but not after mpox vaccination. Here we present a case of recently diagnosed reactive arthritis after mpox vaccination that presented in the context of unrelenting fever and diarrhea complicated by migratory arthritis and anterior uveitis. We have reported this case to the Vaccine Adverse Event Reporting System (VAERS).

Pulmonary Clostridium Perfringens: Seeding Beyond The Gastrointestinal Tract, Thilini Delungahawatta, Shiavax J. Rao, Marcos Wolff, Christopher J Haas

Journal of Community Hospital Internal Medicine Perspectives

Clostridia perfringens infection outside the gastrointestinal system is rare. Here, we report on a 75-year-old man with history of end-stage renal disease presenting after a syncopal event with lactic acidosis, leukocytosis, and mild hyperbilirubinemia. Chest imaging revealed a loculated, left-sided pleural effusion; diagnostic thoracentesis identified Clostridia perfringens, consistent with an empyema. Video-assisted thoracic left lung decortication was performed; tissue culture also speciated Clostridia perfringens. Further imaging revealed concomitant acute cholecystitis, suggesting hematogenous seeding or transdiaphragmatic extension of Clostridia perfringens to pleural space from an abdominal source. The patient was successfully managed with laparoscopic cholecystectomy and discharged on a one-month course …

A Stitch In Time Saves Nine: Planning For Artesunate Supply With Malaria On The Rise, Barath Prashanth Sivasubramanian, Viraj Panchal, Diviya Bharathi Ravikumar, Srikanth Puli, Aalok Khole, Gerard Kiernan, Vikramaditya Samala Venkata

Journal of Community Hospital Internal Medicine Perspectives

Background: Malaria is extremely rare in the United States. Physicians should not only be familiar with signs and symptoms, but also be aware of the available resources at their respective institutions to be able to effectively treat it. Presentation: 52-year-old female presented with worsening generalized fatigue. Vitals were stable. Labs were significant for anemia and thrombocytopenia. Peripheral smear showed ring formed parasitic trophozoites consistent with Plasmodium falciparum. Due to unavailability of antimalarial agents at our hospital, the patient was transferred to a tertiary care center. Patient was started on IV artesunate therapy. Repeat smear after 3 days showed

Compartmental Modeling For The Neophyte: An Application Of Berkeley Madonna, Olcay Akman, Siddharth Bhumpelli, Cody Cline, Christopher Hay-Jahans

Spora: A Journal of Biomathematics

Compartmental modeling serves as a necessary framework in many fields, especially biomathematics and ecology. This article introduces readers to a user-friendly approach to constructing compartmental models and solving the resulting systems of differential equations to simulate real-world applications. The platform used is Berkeley Madonna, a software package that has an intuitive graphical interface which empowers users—even those with limited mathematical and programming backgrounds—to focus on modeling concepts rather than mathematical or programming intricacies. This makes Berkeley Madonna an ideal platform for students, educators, and researchers.

Contrasting Tick Species Behaviors: A Course-Based Undergraduate Research Experience (Cure), Sara Benham, Shovan Dutta, Rohan Maddamsetti, Clayton Wright, Alena Anderson, David T. Gauthier, Holly D. Gaff

Spora: A Journal of Biomathematics

Tick-borne diseases are on the rise throughout the world, and there is a need to better understand tick behavior in order to identify potential new interventions. Ticks have a complex life history and can survive months off-host. There is a lack of large-scale data on off-host tick behavior, which leaves a gap in understanding of tick biology outside of tick-host interactions. Introducing undergraduate students to authentic research early in their studies can help prepare them for independent inquiry in upper-level classes. To address the student needs and fill gaps in tick research, students in introductory biology courses recorded observations of …

Cost-Effectiveness Analysis Of Favipiravir And Remdesivir As Covid-19 Treatment In South Tangerang, Banten Province - Indonesia, Wahyu G. Putro, Andriani R. Fahriyati, Gilberto A. Julian, Tania R. Amalia, Zaki M. Riski

Pharmacology and Clinical Pharmacy Research

COVID-19 is a contagious ailment primarily attributed to the severe acute respiratory syndrome coronavirus. Indonesia persists in confronting the COVID-19 pandemic, and South Tangerang City has emerged as one of the municipalities in Indonesia that has been significantly affected. There are two categories of medications employed for COVID-19 treatment according to government policies, namely favipiravir and remdesivir. This study aims to as- sess the cost-effectiveness of favipiravir and remdesivir medications at the South Tangerang General Hospital, Indonesia. The present study employs a retrospective research design characterized by a quantitative approach, utilizing cross-sectional methodologies. The analy- sis mostly consists of descriptive …

Mass Incarceration In The State Of Louisiana And Its Impact On The Mental Health Of Incarcerated Men, Samika Treniece Miner

Walden Dissertations and Doctoral Studies

No abstract provided.

Coded Social Control: China’S Normalization Of Biometric Surveillance In The Post Covid-19 Era, Michelle Miao

Washington Journal of Law, Technology & Arts

This article investigates the longevity of health QR codes, a digital instrument of pandemic surveillance, in post-COVID China. From 2020 to 2022, China widely used this tri-color tool to combat the COVID-19 pandemic. A commonly held assumption is that health QR codes have become obsolete in post-pandemic China. This study challenges such an assumption. It reveals their persistence and integration - through mobile apps and online platforms - beyond the COVID-19 public health emergency. A prolonged, expanded and normalized use of tools which were originally intended for contact tracing and pandemic surveillance raises critical legal and ethical concerns. Moreover, their …

The Unprecedented Stressors Of Early Childhood Educators During The Covid-19 Pandemic And Post-Pandemic Restoration: A Case Study, Ida Mae Lewis

Doctoral Dissertations and Projects

The purpose of this case study was to describe the unprecedented stressors of early childhood educators (ECE) during the COVID-19 pandemic and the post-pandemic restoration at two early childhood education centers (ECEC) in a midwestern state. The central research question was: How did the COVID-19 pandemic’s unprecedented stressors impact ECE in the post-pandemic era? Data collection included structured interviews with open-ended questions, focus groups, and documents. The three data sources were triangulated for themes, perspectives, and interpretations, and coding was used to help gain a deep understanding of the stressors experienced by early childhood educators. The conceptual framework guiding this …

Assessing Covid-Related Concerns And Their Impact On Antenatal And Delivery Care Among Pregnant Women Living With Hiv In Kenya: A Brief Report., Catherine Wexler, May Maloba, Sharon Mokua, Shadrack Babu, Nicodemus Maosa, Vincent Staggs, Kathy Goggin, Harshdeep Acharya, Emily A. Hurley, Sarah Finocchario-Kessler

Manuscripts, Articles, Book Chapters and Other Papers

BACKGROUND: Some studies indicate that pregnant Kenyan women were concerned about Coronavirus disease 2019 (COVID-19) exposure during maternity care. We assessed concern regarding COVID-19 exposure and any impact on antenatal care (ANC) enrollment and/or hospital delivery among pregnant women living with human immunodeficiency virus (HIV) in Kenya.

METHODS: Data were collected from 1,478 pregnant women living with HIV enrolled in prevention of mother to child transmission of HIV (PMTCT) care at 12 Kenyan hospitals from October 2020 to July 2022. Surveys were conducted when women first presented for PMTCT services at the study hospital and asked demographic questions as well …

Wilms’ Tumor 1 (Wt1) Antigen Is Overexpressed In Kaposi Sarcoma And Is Regulated By Kshv Vflip, Ayana E. Morales, Ruby Gumenick, Caitlin M. Genovese, Yun Yeong Jang, Ariene Ouedraogo, Maite Ibáñez De Garayo, Tania Pannellini, Sanjay Patel, Matthew E. Bott, Julio Alvarez, Sung Soo Mun, Jennifer Totonchy, Archana Gautam, Jesus Delgado De La Mora, Stephanie Chang, Dagmar Wirth, Marcelo Horenstein, Tao Dao, David A. Scheinberg, Paul G. Rubinstein, Aggrey Semeere, Jeffrey Martin, Catherine C. Godfrey, Carlee B. Moser, Roy M. Matining, Thomas B. Campbell, Margaret Z. Borok, Susan E. Krown, Ethel Cesarman

Pharmacy Faculty Articles and Research

In people living with HIV, Kaposi Sarcoma (KS), a vascular neoplasm caused by KS herpesvirus (KSHV/HHV-8), remains one of the most common malignancies worldwide. Individuals living with HIV, receiving otherwise effective antiretroviral therapy, may present with extensive disease requiring chemotherapy. Hence, new therapeutic approaches are needed. The Wilms’ tumor 1 (WT1) protein is overexpressed and associated with poor prognosis in several hematologic and solid malignancies and has shown promise as an immunotherapeutic target. We found that WT1 was overexpressed in >90% of a total 333 KS biopsies, as determined by immunohistochemistry and image analysis. Our largest cohort from ACTG, consisting …

Soft Computing-Based Generalized Least Deviation Methodalgorithm For Modeling And Forecasting Covid-19 Usingquasilinear Recurrence Equations, Mostafa Abotaleb

Iraqi Journal for Computer Science and Mathematics

This study introduces an advanced algorithm based on the Generalized Least Deviation Method(GLDM) tailored for the univariate time series analysis of COVID-19 data. At the core of this approach is theoptimization of a loss function, strategically designed to enhance the accuracy of the model’s predictions. Thealgorithm leverages second-order terms, crucial for capturing the complexities inherent in time series data. Ourfindings reveal that by optimizing the loss function and effectively utilizing second-order model dynamics, there is amarked improvement in the predictive performance. This advancement leads to a robust and practical forecasting tool,significantly enhancing the accuracy and reliability of univariate time series …

Naturally Derived Phenethyl Isothiocyanate Modulates Induction Of Oxidative Stress Via Its N-Acetylated Cysteine Conjugated Form In Malignant Melanoma, Sotiris Kyriakou, Nikoletta Demosthenous, Tom Amery, Kyle J. Stewart, Paul G. Winyard, Rodrigo Franco, Aglaia Pappa, Mihalis I. Panayiotidis

School of Veterinary and Biomedical Sciences: Faculty Publications

Phenethyl isothiocyanate (PEITC) is a secondary metabolic product yielded upon the hydrolysis of gluconasturtiin and it is highly accumulated in the flowers of watercress. The aim of the current study was to assess the role of a naturally derived PEITC-enriched extract in the induction of oxidative stress and to evaluate its anti-melanoma potency through the regulation of its metabolism with the concurrent production of the N-acetyl cysteine conjugated by-product. For this purpose, an in vitro melanoma model was utilized consisting of human primary (A375) cells as well as metastatic (COLO-679) malignant melanoma cells together with non-tumorigenic immortalized keratinocytes (HaCaT). …

Prescribing Pattern Of Vitamins In Dermatologic Disorders At Tertiary Care Teaching Hospital In Western India, Zankrut J. Patel, Akanksha Prajapati, Cidhi Thaker, Sumit Patel

Pharmacology and Clinical Pharmacy Research

Skin ailments are a major burden in society. It is thought that Vitamins may help in improving skin health and appearance, but their deficiency may cause disease. The data regarding vitamin usage patterns in dermatologic practice in India is lacking. Therefore, the present study has been planned to analyze the prescribing pattern of vitamins. A cross-sectional, observational study was carried out at the outpatient department of dermatology at GCSMCH and RC, Ahmedabad, for 12 months from October 2019 to September 2020. Prescriptions of 500 patients were analyzed for common skin conditions and prescribing patterns. All the data were compiled into …

D-Mannose Reduces Cellular Senescence And Nlrp3/Gasdermind/Il-1Β-Driven Pyroptotic Uroepithelial Cell Shedding In The Murine Bladder, Chetanchandra S Joshi, Arnold M Salazar, Caihong Wang, Marianne M Ligon, Rayvanth R Chappidi, Bisiayo E Fashemi, Paul A Felder, Amy Mora, Sandra L Grimm, Cristian Coarfa, Indira U Mysorekar

Faculty, Staff and Students Publications

Aging is a risk factor for disease via increased susceptibility to infection, decreased ability to maintain homeostasis, inefficiency in combating stress, and decreased regenerative capacity. Multiple diseases, including urinary tract infection (UTI), are more prevalent with age; however, the mechanisms underlying the impact of aging on the urinary tract mucosa and the correlation between aging and disease remain poorly understood. Here, we show that, relative to young (8-12 weeks) mice, the urothelium of aged (18-24 months) female mice accumulates large lysosomes with reduced acid phosphatase activity and decreased overall autophagic flux in the aged urothelium, indicative of compromised cellular homeostasis. …

Regional Geographies And Public Health Lessons Of The Covid-19 Pandemic In The Arctic, Sweta Tiwari, Andrey N. Petrov, Nikolay Golosov, Michele Devlin, Mark Welford, John Degroote, Tatiana Degai, Stanislav Ksenofontov

Faculty Publications

Objectives: This study examines the COVID-19 pandemic’s spatiotemporal dynamics in 52 sub-regions in eight Arctic states. This study further investigates the potential impact of early vaccination coverage on subsequent COVID-19 outcomes within these regions, potentially revealing public health insights of global significance. Methods: We assessed the outcomes of the COVID-19 pandemic in Arctic sub-regions using three key epidemiological variables: confirmed cases, confirmed deaths, and case fatality ratio (CFR), along with vaccination rates to evaluate the effectiveness of the early vaccination campaign on the later dynamics of COVID-19 outcomes in these regions. Results: From February 2020 to February 2023, the Arctic …

Elevated Lead Levels In Urban House Sparrows: A Threat To Sharp-Shinned Hawks And Merlins?, Richard B. Chandler, Allan M. Strong, Carlin C. Kaufman

Journal of Raptor Research

No abstract provided.

Mortality, Morbidity, And Lead Poisoning Of Eagles In Western Canada, 1986-98, Mark Wayland, Laurie K. Wilson, John E. Elliott, Michael J. Miller, Trent Bollinger, Malcolm Mcadie, Ken Langelier, Jonathan Keating, Jennifer M. Froese

Journal of Raptor Research

No abstract provided.

A Retrospective Study Of Postmortem Findings In Red-Tailed Hawks, J. Christian Franson, Nancy J. Thomas, Milton R. Smith, Alison H. Robbins, Scott Newman, Paul C. Mccartin

Journal of Raptor Research

No abstract provided.

Diagnostic Findings In 132 Great Horned Owls, J. Christian Franson, Susan E. Little

Journal of Raptor Research

No abstract provided.

Parasitic Helminths Of Six Species Of Hawks And Falcons In Florida, John M. Kinsella, Garry W. Foster, Donald J. Forrester

Journal of Raptor Research

No abstract provided.

Blood Parasites Of Raptors In Florida, Donald J. Forrester, Sam R. Telford Jr., Garry W. Foster, Gordon F. Bennett

Journal of Raptor Research

No abstract provided.

Facts And Artefacts In Nest-Box Studies: Implications For Studies Of Birds Of Prey, Anders Pape Moller

Journal of Raptor Research

No abstract provided.

Diet Of The Red-Backed Buzzard (Buteo Polyosoma Exsul) And The Short-Eared Owl (Asio Flammeus Suinda) In The Juan Fern, Marcelo A. Fuentes, Javier A. Simonetti, M. Soledad Sepulveda, Patricia A. Acevedo

Journal of Raptor Research

No abstract provided.

Precocious Nest Defense Behavior By A Sharp-Shinned Hawk, Robert N. Rosenfield, Andrew Kanvik

Journal of Raptor Research

No abstract provided.

Book Reviews, Journal Of Raptor Research

Journal of Raptor Research

No abstract provided.

Serological Investigation Of Captive And Free Living Raptors, Hans Riemann, Darrell Behymer, Murray Fowler, Dave Ley, Terry Schultz, Roger Ruppanner, Jeff King

Journal of Raptor Research

No abstract provided.