Digital Commons Network^™

Comparison Of The Failure Between Conventional Pmma And Milled Pmma Full Arch Maxillary Interim Prosthesis Fixed On 4 Implants: An In Vitro Study, Tatiana Bou Sakr, Hani Tohme, Natalia Bou Sakr, Victor Ghoubril, Carole Abi Ghosn Yared

International Arab Journal of Dentistry

Objectives: The principal objective of this study was to compare the failure load between the conventional heat polymerized PMMA and the CAD/CAM milled PMMA interim full arch implant prostheses. The secondary aim was to evaluate the success of the distal extension of the temporary PMMA prosthesis.

Methods: A metallic edentulous upper arch model with 4 Straumann screw-retained abutment digital analogs was used to create 15 specimens for each of the 2 groups: Conventional and milled. Failure load was measured on 5 different regions on the left and right side of each specimen with the YLE universal testing machine: …

Investigation Of Fracture Resistance With Different Diameters Of Polyetherketoneketone Post And Core Materials: A Pilot Study, Maya Kabbara, Ryan Harouny, Habib Rahme

International Arab Journal of Dentistry

Objectives: The primary objective of this study is to investigate the resistance to fracture of Polyetherketoneketones PEKK, used as post and core by fabrication in different diameters in the canal, and comparing the test results for each group.

Methods: Thirty extracted mandibular premolars were selected, endodontically treated and prepared to receive the post and cores milled from polyetherketoneketone disk. The specimens were randomly divided into five groups (n = 6) respectively: group 1 received pekk post with diameter = 0.70 mm, group 2 received pekk post with diameter = 0.90 mm, group 3 received pekk post with diameter …

Does Reduced Taper Canal Preparation Increase The Load Capacity Of Endodontically Treated Teeth?, Mostafa M.A. Elkholy, Omar Mahmoud Noureldin, Hala Fayek Khalil, Shehabeldin M. Saber

International Arab Journal of Dentistry

Objectives: The aim of this in-vitro study is to assess and compare the load capacity of teeth with canals prepared using progressive taper versus regressive taper.

Methods: Twenty-seven extracted mandibular molars were categorized into three equal groups. The negative control group involved teeth that were accessed and restored with composite resin without canal preparation. The regressive canal preparation group used the TruNatomy file system, while the progressive canal preparation group employed the ProTaper Gold system. Subsequently, all samples underwent loading using a universal testing machine until tooth fracture occurred. The force required to fracture each tooth was recorded …

Digital Assessment Of Soft And Hard Tissue Alterations After Anterior Maxillary Tooth Extraction, Robin Jalkh, Stephanie Mrad, Emile Chrabieh, Joe Bassil

International Arab Journal of Dentistry

Objectives: This study aimed to assess dimensional alterations in soft and hard tissues 12 weeks post-extraction using novel computerized methods. Secondary objectives included exploring potential correlations between soft tissue changes and underlying bone variations, as well as investigating relationships between soft and hard tissue alterations and various contributing factors.

Methods: For all patients, preoperative and postoperative CBCT scans and intra-oral scans were obtained. Soft and hard tissue dimensions before extraction and at 12 weeks post-extraction were measured using 3D-slicer software. Both DICOM and STL files were superimposed, and measurements were taken at 2mm and 4mm from the facial …

Evaluation Of Fracture Resistance Of Composite Resin And Glass Ionomer In Beveled Versus Non-Beveled Class Ii Restorations In Primary Molars: An In Vitro Comparative Study, Suzanne Abou Aziz, Cynthia Kassis, Ryan Harouny, Lara Nasr, Georges El Najjar, Marlene Khoury

International Arab Journal of Dentistry

Introduction: The high viscosity Bulk-Fill composite (Tetric N ceram) and high viscosity glass ionomer cement (Equia Forte GIC) are the most used materials in class II cavities of primary molars. They have the advantages of being placed in a single layer of 4mm and therefore allow better ergonomics and speed of use. Until now, we find failures of restorations at the level of class II cavities of temporary teeth and many authors have tested the role of the bevel in improving the mechanical strength of restorations.

Objectives: The objectives of this study are: to test the role of …

Assessment And Quantification Of The Microbial Flora In The Output Water Of Two Types Of Dental Chairs: A Comparative Study, Khalil Kharma, Louis Hardan, Cynthia Kassis, Rim Bourgi, Regina Geitani, May Mallah, Elie Maalouf, Carina Mehanna Zogheib

International Arab Journal of Dentistry

Objectives: Dental Unit Waterlines (DUWL) have shown to be a perfect host for different pathogenic microorganisms. The purpose of this study was to analyze and compare the level of bacterial contamination in the output water of 2 types of DUWL.

Methods: Dental unit water samples from the air/water syringe of the A-dec (A-dec™ Performer 200, Newberg, USA) DUWL type and KaVo (ESTETICA™ E30/E70/E80 Vision, Kavo, Biberach, Germany) type were collected and analyzed for total aerobic flora, Pseudomonas aeruginosa, faecal coliforms, total coliforms, faecal streptococci and sulfite-reducing anaerobic flora.

Results: The bacteriological analysis of water samples shows the …

Clinical Assessment Of The Abutment Teeth Of Children Undergoing Space Maintainer Therapy: A Randomised Controlled Trial, Ayesha Fathima, Ganesh Jeevanandan, Prabhadevi Maganur, Suman Panda, Ather Syed Ahmed, Satish Vishwanathaiah

International Arab Journal of Dentistry

Introduction: The band and loop space maintainer are one of the most commonly used fixed space maintainers in children. However, prolonged use of appliances in the oral cavity may lead to changes in gingival health and an increased risk of caries.

Objectives: This study aims to evaluate the clinical parameters of the abutment teeth, specifically the banded teeth and the tooth to which the loop is extended.

Methods: This prospective clinical study included 35 children between the age group of 5 to 9 years. The children were examined at baseline and 6-month follow-up. The abutment teeth were …

Comparative Evaluation Of Surface Changes And Bond Strength Of Microabrasion-Bleached Enamel Before And After Remineralization With Nano-Hydroxyapatite Paste: An In Vitro Study, Ridhi Dube, Anita Sanap Tandale, Twinkle Kishore Talreja, Karishma Krishnakumar, Prajakta Kokate, Vaishnavi Jemini Kasat

International Arab Journal of Dentistry

Objectives: Comparative evaluation of surface changes and bond strength of Microabrasion Bleached enamel before and after Remineralization with Nano-hydroxyapatite paste, an In vitro study.

Methods: Enamel samples were divided into - Group I - Conventional bleaching (HB), Group II - Conventional bleaching with remineralization (HB+N-Hp), Group III - Microabrasion-assisted bleaching(M+HB), and Group IV - Microabrasion-assisted bleaching with remineralization(M+HB+NHp). Surface roughness was measured using a profilometer. Samples were stored in artificial saliva for two weeks, then bonded with nanofilled composite resin and subjected to shear bond strength (SBS) analysis.

Results: Group IV (M+HB+N-Hp) showed higher surface roughness than …

A Comparison Between The Flexural Strength Of Milled, Conventional, And Carbon Fiber Pmma For Interim Implant-Supported Fixed Complete Dentures: An In Vitro Study, Jenny Abou Nader, Paul Boulos, Jihad Fakhouri, Nancy Chemaly, Carol Abi Ghosn

International Arab Journal of Dentistry

Objectives: to investigate the flexural strength of three materials commonly used for interim implant-supported fixed complete dentures (ISFCDs): conventional heat cure PMMA, CAD/CAM milled PMMA, and carbon fiber-reinforced PMMA.

Methods: Sixty specimens (n=60) divided equally into three groups (heat cure, milled, carbon fiber) were prepared. Samples were inspected to ensure absence of voids or irregularities and when required, minor adjustments were made to adjust the dimensions. The samples underwent thermocycling (5-55°C for 2500 cycles) and were then tested using a three-point bend test.

Results: There was a statistically significant difference between heat cure PMMA and carbon fiber …

Aesthetic Rehabilitation Of A Complex Crown-Root Fracture By Fragment Reattachment With A Fiber-Reinforced Post: A Case Report, Sarra Saidi, Meriem Fejjeri, Mahdi Tlili, Sabra Jaafoura, Nadia Frih

International Arab Journal of Dentistry

Complex crown-root fractures are characterized by the involvement of both crown and root with pulp exposure. They pose aesthetic, functional, and psychological problems for the patient. Furthermore, they can pose technical difficulties for the practitioner. The purpose of this case report is to describe the management of a complex crown-root fracture of the right upper central incisor with subgingival limit by reattaching the tooth fragment with fiber-reinforced post. We considered a coronal elongation (gingivectomy and osteoplasty) to recreate the biological space and to expose the limit of the fracture line to guarantee the quality of the bond.

Clinical Management Of Mandibular Permanent Premolars With Periapical Lesion And Bilateral Supernumerary Teeth: A 7-Year Follow-Up Case Report, Chiara Pirani, Shehabeldin Saber, Francesco Iacono

International Arab Journal of Dentistry

Objectives: This 7-years follow-up case report describes two diversified strategies for the management of bilateral mandibular permanent premolars associated with periapical lesion and unerupted supernumerary teeth.

Case Report: A non-syndromic 9 years-old Asian female patient presented pain and swelling of the 35 in anatomical contiguity with an immature and unerupted supernumerary tooth. Clinical examination revealed an intraoral vestibular sinus tract related to the necrotic 35. Periapical radiography and CBCT showed that the 35 had an immature apex associated with a periapical lesion, and a supernumerary tooth in a lingual direction. Endodontic treatment of the 35 was performed by creating …

Does The Application Of Polywave Light-Curing Units Influence Physico-Mechanical Properties Of Resin-Based Materials? A Meta-Analysis Of In Vitro Studies, Miguel Ángel Fernández-Barrera, Rim Bourgi, Abigailt Flores-Ledesma, Cristina Pereira Isolan, Vincenzo Tosco, Bogdan Dimitriu, Carlos Enrique Cuevas-Suárez, Monika Lukomska-Szymanska, Louis Hardan

International Arab Journal of Dentistry

The objective of this study was to systematically review the existing literature and to assess the effect of the use of polywave light-curing units on the properties of resin-based materials. A thorough search was conducted across five electronic databases: PubMed (MedLine), ISI Web of Science, SciELO, Scopus, and EMBASE. Inclusion criteria comprised in-vitro studies that compared the effects of polywave light-emitting diode (LED) curing units with monowave LED curing units on resin-based material properties. Two reviewers evaluated the methodological quality of the included studies, considering parameters from previous systematic reviews. Meta-analyses were conducted using Review Manager version 5.3.5 (The Cochrane …

Regulatory Autonomy And Article Xxiv Of Gatt, Dr. Delroy S. Beckford

Indian Journal of International Economic Law

This article focusses on regulatory autonomy in the context of Article XXIV of GATT navigating issues which touch and concern the internal and external liberalisation requirements and their implication for core non-discrimination principles, the Enabling Clause, mutual recognition agreements, and specific disciplines such as trade remedies, SPS measures, TBT measures, and Article XX exceptions. The article proceeds on the premise that these areas of trade coverage offer significant scope for the realisation of regulatory autonomy for countries to fashion their domestic trade policy agenda consistent with their developmental requirements, but questions whether the current state of the jurisprudence is amenable …

Establishing A Quantitative Assessment Tool For Biophilia In Healthcare Facilities, Sara Moustafa Fouda, Mohanad Ali Fouda

Mansoura Engineering Journal

This study aims at developing a novel assessment tool that can quantitatively evaluate the level of biophilia integration in healthcare facilities. The developed assessment tool helps to address the difficulty of biophilia quantification in the built environment due to the broad nature of the biophilia concept. The methodological approach for the tool depends on employing biophilic design patterns as a basis for biophilia, where these patterns are correlated to a group of biophilia-related features of the WELL Building Standard. This correlation is attained through a list of Integrated Design Guidelines (IDGs) that is proposed to act as an intermediate ground …

Enhancing The Perception Of Public Urban Spaces Via Place-Making: Martyrs' Square And Selected Locations In El-Gaish Street Case Study, Vert Kamal Ramzy, Nanees Abdel Hamid Mohamed Ali Elsayyad, Lamis Saad El-Din El-Gizawi

Mansoura Engineering Journal

Trust be told that urban spaces have generated a lot of controversy in recent years. The major issues that I will address in this paper are transformations in the urban environment affected by different appearances due to economic and social changes that shape their meaning through human interactions for creating a social life. With the emergence of modern architecture and planning patterns, urban spaces have become the focus of researchers for study and analysis to determine the best destination.

This paper aims to present place-making as an approach to strengthening the perception of public urban spaces and, consequently, its impact …

Women And Trade In Africa: A Case For Mainstreaming Gender In The Implementation Of The African Continental Free Trade Agreement (Afcfta), Tsotang Tsietsi

Indian Journal of International Economic Law

This article seeks to determine the extent to which the African Continental Free Trade Agreement (AfCFTA) and its protocols accord attention to the barriers and opportunities that African women face in intra-African trade. It discusses the considerable role of African women traders, for example, in agriculture, micro, small and medium enterprises, and in informal cross border trade. It questions whether, in support of their contributions in these sectors, gender has been adequately mainstreamed in the AfCFTA legal framework. Through its analysis of the contents of the instruments, it argues that there was little prioritization of women in the agreement and …

White Girl Wasted: Gender Performativity Of Sexuality With Alcohol In National Panhellenic Conference Sorority Women, Pietro A. Sasso, Amber Manning-Ouellette, Kim E. Bullington, Shelley Price-Williams

Journal of Higher Education & Student Affairs

This narrative qualitative study explored how sorority members negotiated their identities within systems of hegemony with their student communities. Sorority members used women’s empowerment discourse to rationalize how they consumed alcohol, engaged in frequent consensual sexual relationships, and navigated relationships with fraternity men and across their campus sorority/fraternity communities. Implications for practice included harm reduction, sex education, and supportive policies.

Understanding The Role Of Cultural Competence In Peer Mentorship Programs For International Students: A Student Development Theory Perspective, Nikheal Patel, Daniel Calhoun, Steven Tolman

Journal of Higher Education & Student Affairs

International students often face challenges while pursuing higher education in a foreign country. These challenges can negatively impact their sense of belonging and community, resulting in social disconnection. Examining the role of culturally competent peer mentoring programs for international students can foster a sense of belonging among international students. Peer mentorship may provide international students with a supportive environment and community, helping them navigate university life. In contrast, student development theory can inform the design of programs and services that support international students in their transition to American higher education. These strategies can create a more inclusive and welcoming environment …

Acute Brachial Artery Occlusion Following Cisplatin-Based Chemotherapy: Case Report, Abenezer Melaku Tafese, Amanuel Yegnanew Adela, Assefa Getachew Kebede, Aklilu Sinte Tegegn, Elsabeth Tizazu Asare, Munir Awol

Student Papers, Posters & Projects

Thromboembolism is a significant cause of mortality and morbidity in cancer patients. While the link between cancer and venous thrombosis is well known, the recognition of arterial thrombosis as a serious complication of cancer and chemotherapeutic agents is a recent development. One of the chemotherapy agents frequently linked to acute vascular events is cisplatin. We discuss a rare case of cisplatin-related brachial arterial thrombosis in a 50-year-old man who was treated for cholangiocarcinoma with cisplatin and gemcitabine. Although rare, cisplatin-related arterial thrombosis demands careful monitoring, a high index of suspicion, and prompt management to prevent serious complications and mortality.

Mapping Patients’ Online Record Access Worldwide: Preliminary Results From An International Survey Of Healthcare Experts, A Kharko, C Blease, M Johansen, A Moen, Et Al

Peninsula Medical School

While research on the effects of patient access to health records is increasing, a basic understanding of the spread of patient-accessible electronic health records worldwide is lacking. In this survey of healthcare experts with professional and personal experience from 29 countries, we explored the state of patient online record access (ORA). We asked participants whether ORA exists in their country and which information is available through it. Experts in all polled countries reported having some national access to health records, with 6 (21%) countries providing exclusively paper-based records and 23 (79%) countries having ORA. Overview of test/lab results and prescription/medication …

Interim Best Practice Guidelines For Training Professional Carers In The Administration Of Buccal (Oromucosal) Midazolam For The Treatment Of Prolonged And/Or Clusters Of Epileptic Seizures In The Community, Rohit Shankar

Peninsula Medical School

No abstract provided.

The Mini-Cog: A Community Screening Tool For Dementia In Indonesia, Yuda Turana, Nicolas Farina, Imelda Theresia, Tara Puspitarini Sani, Ika Suswanti, Fasihah Irfani Fitri, Emiliano Albanese, Adelina Comas-Herrera, Martin Knapp, Sube Banerjee

Peninsula Medical School

Background: Early detection of dementia enables more effective planning and can enable access to treatment and support. The Mini-Cog is a widely used screening instrument in Indonesia; however, this instrument has never undergone a translation and cultural adaptation process. Currently, there is no data on how accurate the tool is against diagnostic criteria, particularly in low-education. Methods: Embedded within the community-based dementia prevalence study was the Strengthening Responses to Dementia in Developing Countries (STRiDE) project; older adults (aged ≥ 65 years) were randomly recruited from sites in Jakarta and North Sumatra, Indonesia. All participants were asked to complete the Mini-Cog …

Association Between Glucagon-Like Peptide-1 Receptor Agonists Use And Change In Alcohol Consumption: A Systematic Review, Mohsan Subhani, Ashwin Dhanda, James A. King, Fiona C. Warren, Siobhan Creanor, Melanie J. Davies, Sally Eldeghaidy, Stephen Bawden, Penny A. Gowland, Ramon Bataller, Justin Greenwood, Stephen Kaar, Neeraj Bhala, Guruprasad P. Aithal

Peninsula Medical School

Background: Despite the availability of various pharmacological and behavioural interventions, alcohol-related mortality is rising. This systematic review aimed to critically evaluate the existing literature on the association between glucagon-like peptide-1 receptor agonists use (GLP-1 RAs) and alcohol consumption. Methods: Electronic searches were conducted on Ovid Medline, EMBASE, PsycINFO, clintrials.gov, and ProQuest until the end of March 2024. An updated search was done on 7th of August 2024. The primary outcome was to explore the association between GLP-1 RAs use and change in alcohol consumption. Secondary outcomes included evaluating the impact of GLP-1 RAs on occurrences of alcohol-related events, healthcare utilisation, …

Which Components Of Behavioral Weight Management Programs Are Essential For Weight Loss In People Living With Obesity? A Rapid Review Of Systematic Reviews, The Progroup Programme Team, Lily K. Hawkins, Lorna Burns, Dawn Swancutt, Shokraneh Moghadam, Jonathan Pinkney, Mark Tarrant

Peninsula Medical School

The optimal treatment and organization of care for people with obesity is one of the greatest challenges facing today's health services. While surgery and pharmacotherapy offer effective treatment options for some people with obesity, behavioral interventions are important to support long-term behavioral change. However, little is known about the most effective components of behavioral interventions, and this is especially the case for people with complex or severe obesity (i.e. body mass index [BMI] > 35 kg/m²). Accordingly, the current rapid review aimed to identify which behavior change techniques (BCTs) are effective for weight loss in adults with (severe) obesity. …

A Study Of Referral Bias In Nmosd And Mogad Cohorts, Miguel Leal Rato, Bo Chen, Anna Francis, Silvia Messina, Madalina Miron, Yvonne Sharawakanda, Eoin O'Sullivan, Sarah Cooper, Leonora Fisniku, Christopher Halfpenny, Roswell Martin, Jeremy Hobart, Waqar Rashid, Cheryl Hemingway, Victoria Williams, Yael Hacohen, Ruth Dobson, Sithara Ramdas, Maria Isabel Leite, Jacqueline Palace, Ruth Geraldes

Peninsula Medical School

Background: Neuromyelitis optica spectrum disorder (NMOSD) and myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD) are rare disorders often seen in highly specialized services or tertiary centres. We aimed to assess if cohort characteristics depend on the origin of the referral catchment areas serviced by our centre (i.e. local, regional or national). Methods: Retrospective cohort study using a national referral service database including local (Oxfordshire), regional (Oxfordshire and neighbouring counties), and national patients. We included patients with the diagnosis of NMOSD, seronegative NMOSD or MOGAD, followed at the Oxford Neuromyelitis Optica Service. Results: We included 720 patients (331 with MOGAD, 333 with …

Identification Of Druggable Regulators Of Cell Secretion Via A Kinome-Wide Screen And High-Throughput Immunomagnetic Cell Sorting, Mahmoud Labib, Zongjie Wang, Yunhye Kim, Sichun Lin, Abdalla Abdrabou, Hanie Yousefi, Pei Ying Lo, Stéphane Angers, Edward H. Sargent, Shana O. Kelley

Peninsula Medical School

The identification of genetic regulators of cell secretions is challenging because it requires the sorting of a large number of cells according to their secretion patterns. Here we report the development and applicability of a high-throughput microfluidic method for the analysis of the secretion levels of large populations of immune cells. The method is linked with a kinome-wide loss-of-function CRISPR screen, immunomagnetically sorting the cells according to their secretion levels, and the sequencing of their genomes to identify key genetic modifiers of cell secretion. We used the method, which we validated against flow cytometry for cytokines secreted from primary mouse …

Covid And Mental Health In People With Intellectual Disability, Rohit Shankar

Peninsula Medical School

No abstract provided.

Open‐Label, Clinical Trial Extension: Two‐Year Safety And Efficacy Results Of Seladelpar In Patients With Primary Biliary Cholangitis, Marlyn J. Mayo, John M. Vierling, Christopher L. Bowlus, Cynthia Levy, Gideon M. Hirschfield, Guy W. Neff, Michael R. Galambos, Stuart C. Gordon, Brian B. Borg, Stephen A. Harrison, Paul J. Thuluvath, Aparna Goel, Mitchell L. Shiffman, Mark G. Swain, David E.J. Jones, Palak Trivedi, Andreas E. Kremer, Richard J. Aspinall, David A. Sheridan, Yvonne Dörffel, Ke Yang, Yun Jung Choi, Charles A. Mcwherter

Peninsula Medical School

Background Seladelpar is a potent and selective peroxisome proliferator-activated receptor-δ agonist that targets multiple cell types involved in primary biliary cholangitis (PBC), leading to anti-cholestatic, anti-inflammatory and anti-pruritic effects. Aims To evaluate the long-term safety and efficacy of seladelpar in patients with PBC. Methods In an open-label, international, long-term extension study, patients with PBC completing seladelpar lead-in studies continued treatment. Seladelpar was taken orally once daily at doses of 5 or 10 mg with dose adjustment permitted for safety or tolerability. The primary analysis was for safety and the secondary efficacy analysis examined biochemical markers of cholestasis and liver injury. …

Digital Image Correlation Guided Wearable Sensor Design And Fabrication Of Novel Microfluidic Pump For Human Movement Classification Using Machine Learning Models, Nick Cmager

Bioengineering Master's Theses

Wearable technologies are transforming healthcare and enabling physicians to customize treatments through continuous non-invasive data acquisition. Microfluidic sensors have been gaining attention due to their flexibility and ability to conform to the human skin. However, individual variations in skin properties necessitate personalized sensor designs. This thesis presents a novel approach for designing and fabricating wearable microfluidic sensors, leveraging digital image correlation (DIC) to guide the development of a microfluidic pump for human movement classification. An open-source DIC platform Ncorr was utilized for 2D and 3D DIC analysis of human skin strain. The results were used to guide the design of …

Did Asu 2020-06 Impact Firm Corporate Financing Decisions?, Eric Sanchez

CMC Senior Theses

This research examines the influence of financial accounting standards for hybrid securities on corporate financing decisions. It uses ASU-2020-06 as a setting to test changes to the influence of moral hazard, adverse selection, and financial distress contracting costs on the likelihood of convertible bond issuances under the prior and latter accounting regimes for securities convertible into an entity's own equity.