Digital Commons Network^™

Maternal Morbidity Associated With Early Preterm Birth In Low-Risk Singleton Pregnancies, Moti Gulersen, Erez Lenchner, Alisha Goyal, Amos Grunebaum, Frank A. Chervenak, Eran Bornstein

Department of Obstetrics and Gynecology Faculty Papers

Background/Objectives: While neonatal morbidities associated with early preterm birth are known, the risks of maternal morbidities in these births remain unclear. Thus, we set out to assess the risk of maternal morbidities associated with early preterm births. Methods: Retrospective cohort study utilizing the United States (US) Natality Live Birth database from the Centers for Disease Control and Prevention (2016–2021). Low-risk singleton pregnancies were included. High-risk conditions such as out-of-hospital births, fetal anomalies, pregestational and gestational diabetes, and hypertensive disorders of pregnancy were excluded. The rates of several maternal morbidities were compared among three gestational age at birth groups: 23 0/7–27 …

Sumukh Llc And Nalin Bhatt, Appellants V. Russell A. Cline Pc, Russell Cline, Crippen & Cline, L.C, Appellees : Brief Of Appellant, Utah Court Of Appeals

Utah Court of Appeals Briefs (2020 –)

appeal from the Third Judicial District Court, Salt Lake County, Honorable James D. Gardner, District Court No. 190902530 __________________ Russell A. Cline CRIPPEN and CLINE, LC

Telecommuting Policy (11-22-2024), Associated Students, Incorporated

Associated Students, Incorporated records

No abstract provided.

¡Viva Puerto Rico! How Puerto Rico's Political And Economic Status Has Affected Its Vulnerability To Natural Hazards, Mystique Quintana

University Honors Theses

Using Hurricane Maria as a case study, this thesis examines Puerto Rico's vulnerability to natural disasters and explores the intersections between colonial history, political status, and socioeconomic inequalities. Undertaking the island's susceptibility to environmental crises based on centuries of colonial exploitation and dependence, along with restrictive U.S. policies. It is argued that policies like the Jones Act, Operation Bootstrap, and PROMESA perpetuate systemic neglect and undermine disaster preparedness. Due to these structural vulnerabilities, intensified by climate change, Puerto Rico is ill-equipped to recover from hurricanes. During Hurricane Maria, systemic governance failures, inadequate infrastructure, and insufficient federal aid exposed these deep-rooted …

Mitochondrial Heteroplasmy Improves Risk Prediction For Myeloid Neoplasms, Yun Soo Hong, Sergiu Pasca, Wen Shi, Daniela Puiu, Nicole J Lake, Monkol Lek, Meng Ru, Megan L Grove, Anna Prizment, Corinne E Joshu, Elizabeth A Platz, Eliseo Guallar, Dan E Arking, Lukasz P Gondek

Faculty, Staff and Student Publications

Clonal hematopoiesis of indeterminate potential is the primary pathogenic risk factor for myeloid neoplasms, while heteroplasmy (mutations in a subset of cellular mitochondrial DNA) is another marker of clonal expansion associated with hematological malignancies. We explore how these two markers relate and influence myeloid neoplasms incidence, and their role in risk stratification. We find that heteroplasmy is more common in individuals with clonal hematopoiesis of indeterminate potential, particularly those with higher variant allele fractions, multiple mutations, or spliceosome machinery mutations. Individuals with both markers have a higher risk of myeloid neoplasms than those with either alone. Furthermore, heteroplasmic variants with …

November 22, 2024 Minutes, Swosu Faculty Senate

Faculty Senate Minutes

No abstract provided.

Fouad Named Chair Of The Ada Council On Scientific Affairs, Staff

Browse All News

No abstract provided.

Executive Summary: Staff Education Project Staff Education Regarding Menopause Hormonal Use In A Women's Clinic, Patricia Leal

Walden Dissertations and Doctoral Studies

This DNP project entails staff education regarding menopause hormonal use in a women's clinic. The practice problem was the lack of staff confidence regarding hormone use in menopausal women. It is essential to address the practice problem within the context of nursing practice because it can potentially enhance positive social change by addressing the healthcare needs of an underserved demographic. The project aimed to develop and deliver an education program regarding the care of menopausal women for staff members in the women's clinic. The project question was whether staff education regarding menopause hormonal use could increase confidence among staff in …

Effective Strategies To Decrease Employee Turnover In The Aviation Industry, Jasmina Tabakovic

Walden Dissertations and Doctoral Studies

Employee turnover in the airline industry has been a timely and pressing problem. Some airline managers had not developed effective strategies to reduce employee turnover and mitigate turnover-related costs and organizational instability. Grounded in Herzberg et al.’s two-factor theory, the purpose of this qualitative pragmatic study was to explore effective strategies used by airline managers to reduce employee turnover and mitigate turnover-related costs and organizational instability. The participants were six airline managers in the United States who had developed effective strategies to minimize employee turnover and enhance organizational stability and profits. Data were collected using semi-structured interviews and publicly available …

Implementing Motivational Interviewing And Psycho-Education To Improve Medication Adherence Among Patients With Schizophrenia, Francis Ihejirika

Walden Dissertations and Doctoral Studies

This quality improvement staff education Doctor of Nursing practice (DNP) project was implemented to address the quality issue related to medication nonadherence in patients with schizophrenia. Medication nonadherence is a major health issue facing psychiatric patients, with studies showing high rates of nonadherence among patients with schizophrenia. Nonadherence to treatment heightens the risk of relapse, rehospitalization, suicide, and early death. This staff education project focused on increasing the knowledge and attitudes of healthcare professionals about evidence-based strategies to improve medication adherence in patients with schizophrenia. Five nurses participated in the education program. The participants completed the pretest prior to participating …

Effective Strategies To Decrease Employee Turnover In The Aviation Industry, Jasmina Tabakovic

Walden Dissertations and Doctoral Studies

Employee turnover in the airline industry has been a timely and pressing problem. Some airline managers had not developed effective strategies to reduce employee turnover and mitigate turnover-related costs and organizational instability. Grounded in Herzberg et al.’s two-factor theory, the purpose of this qualitative pragmatic study was to explore effective strategies used by airline managers to reduce employee turnover and mitigate turnover-related costs and organizational instability. The participants were six airline managers in the United States who had developed effective strategies to minimize employee turnover and enhance organizational stability and profits. Data were collected using semi-structured interviews and publicly available …

Efficacy Of Banana Fibre Paper For The Management Of The Root-Knot Nematode, Meloidogyne Incognita, On Potato (Solanum Tuberosum) In Kenya, Dorris W. Kamau, Wanjohi Waceke, Laura Cortada, Onesmus Mwaura, Tahira Pirzada, Tim L. Sit, Eric Davis, Dick Guenther, Reny Mathew, Lokendra Pal, Saad Khan, Solveig Haukeland, James Kisaakye, Charles Opperman, Danny Coyne

All Peer-Reviewed Publications

Globally, potato (Solanum tuberosum) is a key staple food crop. In Kenya, it is the second most important food crop after maize. Among the various constraints to potato production are plant-parasitic nematodes. In particular, root-knot nematodes (Meloidogyne spp.) are a significant impediment to potato production, suppressing yield and reducing the quality of harvested tubers. The current study was undertaken to evaluate the efficacy of a lignocellulose fibre matrix (banana paper) either impregnated with a chemical or drenched with a biologically-based nematicide for the management of root-knot nematodes on potatoes, in Kenya. The experiment was conducted in both field and pot …

The Zircon, November 22, 2024 [Spoof Issue], Dordt University

Dordt Diamond

No abstract provided.

Neuroprotective Effect Of L-Dopa-Induced Interleukin-13 On Striatonigral Degeneration In Cerebral Ischemia, Eunhae Jeon, Myeong-Seong Seo, Enkhmaa Lkhagva-Yondon, Yu-Ree Lim, Seung-Woo Kim, Yu Jeong Kang, Jun Seok Lee, Byoung Dae Lee, Rayul Wi, So-Yoon Won, Young Cheul Chung, Eun S Park, Eunhee Kim, Byung Kwan Jin, Myung-Shin Jeon

Faculty, Staff and Student Publications

Levodopa (L-DOPA) treatment is a clinically effective strategy for improving motor function in patients with ischemic stroke. However, the mechanisms by which modulating the dopamine system relieves the pathology of the ischemic brain remain unclear. Emerging evidence from an experimental mouse model of ischemic stroke, established by middle cerebral artery occlusion (MCAO), suggested that L-DOPA has the potential to modulate the inflammatory and immune response that occurs during a stroke. Here, we aimed to demonstrate the therapeutic effect of L-DOPA in regulating the systemic immune response and improving functional deficits in mice with ischemia. Transient MCAO led to progressive degeneration …

Towards An International, Generalizable Marketing Strategy Maturity Model, Juan Manuel Harraca

USF Tampa Graduate Theses and Dissertations

In an increasingly dynamic business environment, organizations face relentless pressure to adapt their strategies and optimize value propositions to maintain competitiveness. The formulation of effective marketing strategies has emerged as a critical factor in achieving sustainable competitive advantage and ensuring long-term success. However, many firms struggle to refine their marketing capabilities in response to evolving market demands. Addressing this challenge, the Marketing Strategy Maturity Model (MSMM), introduced by Harraca in 2023, offers a structured framework to assess and improve a firm’s marketing strategy formulation processes.

The MSMM provides a dual approach, emphasizing the enhancement of both the processes and the …

Clc-Kb Pore Mutation Disrupts Glycosylation And Triggers Distal Tubular Remodeling, Yogita Sharma, Robin Lo, Viktor N Tomilin, Kotdaji Ha, Holly Deremo, Aishwarya V Pareek, Wuxing Dong, Xiaohui Liao, Svetlana Lebedeva, Vivek Charu, Neeraja Kambham, Kerim Mutig, Oleh Pochynyuk, Vivek Bhalla

Faculty, Staff and Student Publications

Mutations in the CLCNKB gene (1p36), encoding the basolateral chloride channel ClC-Kb, cause type 3 Bartter syndrome. We identified a family with a mixed Bartter/Gitelman phenotype and early-onset kidney failure and by employing a candidate gene approach, identified what we believe is a novel homozygous mutation (CLCNKB c.499G>T [p.Gly167Cys]) in exon 6 of CLCNKB in the index patient. We then validated these results with Sanger and whole-exome sequencing. Compared with wild-type ClC-Kb, the Gly167Cys mutant conducted less current and exhibited impaired complex N-linked glycosylation in vitro. We demonstrated that loss of Gly-167, rather than gain of a mutant Cys, …

Impact Of Dietary Fiber On Inflammation Related To Type 2 Diabetes, Alexander Berg

Electronic Theses and Dissertations Archive

The American diet, marked by high refined carbohydrate intake and low dietary fiber, is closely linked to the rising prevalence of Type 2 Diabetes (T2D) and associated inflammatory diseases. This review highlights the role of dietary fiber in preventing and managing inflammation from T2D. A daily intake of over 25 g for women and 38 g for men can reduce T2D risk by 20-30%. Specifically, high cereal fibers correlate with a 33% reduction in risk, while soluble fibers from fruits and vegetables mitigate postprandial glucose spikes, enhancing insulin sensitivity. Additionally, a high-fiber diet can reverse insulin resistance; a study revealed …

Effective Strategies To Decrease Employee Turnover In The Aviation Industry, Jasmina Tabakovic

Walden Dissertations and Doctoral Studies

Employee turnover in the airline industry has been a timely and pressing problem. Some airline managers had not developed effective strategies to reduce employee turnover and mitigate turnover-related costs and organizational instability. Grounded in Herzberg et al.’s two-factor theory, the purpose of this qualitative pragmatic study was to explore effective strategies used by airline managers to reduce employee turnover and mitigate turnover-related costs and organizational instability. The participants were six airline managers in the United States who had developed effective strategies to minimize employee turnover and enhance organizational stability and profits. Data were collected using semi-structured interviews and publicly available …

Executive Summary: Staff Education Project Staff Education To Enhance Nursing Competency Through Simulation Technology, Mollie Mae Ellington

Walden Dissertations and Doctoral Studies

Simulation-based training is a key component of nursing education, providing immersive, hands-on experiences that enhance clinical skills in a controlled environment. In the local organization, leadership determined there was an underutilization of advanced simulation equipment stemming from a lack of standardized training among staff. Thus, the purpose of this Doctor of Nursing Practice (DNP) project was to determine whether an educational intervention focused on simulation improved competency among nurses at a local health care organization. To measure competency, 15 items from the Nurse Professional Competence Scale were used. Fifty-eight individuals were invited to participate in the educational intervention, and a …

Volunteer Perceptions Of Commitment In A Humanitarian Organization Involved With Nigerian Community Development Projects, Olaitan Ojuroye

Walden Dissertations and Doctoral Studies

Research has shown that output from volunteers is unpredictable and uncontrollable, rendering strategic planning futile for organizations. This study explored adult volunteers' lived experiences regarding their perceptions of commitment to a humanitarian organization involved with Nigerian community development projects. Identifying why volunteers adopted attitudes was essential to support the organization's development and promote the community's development by helping practitioners better understand the volunteers and deploy them more appropriately. The framework that grounded this study included psychological contract theory, organizational commitment, and social undermining. This interpretative phenomenological analysis study involved a purposeful sample of 10 adult volunteers who participated in semistructured …

Editorial: Cardiogenic Shock: Basic And Clinical Consideration, Volume Ii, Umberto Di Dedda, Indranee Rajapreyar, J. Eduardo Rame, Clement Delmas, Paolo Meani

Division of Cardiology Faculty Papers

No abstract provided.

Applications Of Computer Vision In Biomechanics And Orthopaedics, William Stewart Burton Ii

Electronic Theses and Dissertations

Machine learning has emerged as a key technology for enabling advanced computer vision systems. These systems now permeate many industries, and have enhanced traditional processes through autonomous interpretation of visual data. In the field of orthopaedics, the increasing prevalence of imaging highlights a need for similar tools. In many cases, however, direct translation of available frameworks fails to resolve the complex problems currently facing this field. Stringent performance requirements, complex visual environments, data scarcity, and implications for patient safety represent domain-specific factors which pose unique challenges to proven techniques. Novel approaches are needed to realize the full benefits of visual …

Identification Of Lrp1+Cd13+ Human Periosteal Stem Cells That Require Lrp1 For Bone Repair, Youngjae Jeong, Lorenzo Deveza, Laura Ortinau, Kevin Lei, John R Dawson, Dongsu Park

Faculty, Staff and Students Publications

Human periosteal skeletal stem cells (P-SSCs) are critical for cortical bone maintenance and repair. However, their in vivo identity, molecular characteristics, and specific markers remain unknown. Here, single-cell sequencing revealed human periosteum contains SSC clusters expressing known SSC markers, podoplanin (PDPN) and PDGFRA. Notably, human P-SSCs, but not bone marrow SSCs, selectively expressed identified markers low density lipoprotein receptor-related protein 1 (LRP1) and CD13. These LRP1+CD13+ human P-SSCs were perivascular cells with high osteochondrogenic but minimal adipogenic potential. Upon transplantation into bone injuries in mice, they preserved self-renewal capability in vivo. Single-cell analysis of mouse periosteum further supported the preferential …

A Proteogenomic Analysis Of Cervical Cancer Reveals Therapeutic And Biological Insights, Jing Yu, Xiuqi Gui, Yunhao Zou, Qian Liu, Zhicheng Yang, Jusheng An, Xuan Guo, Kaihua Wang, Jiaming Guo, Manni Huang, Shuhan Zhou, Jing Zuo, Yimin Chen, Lu Deng, Guangwen Yuan, Ning Li, Yan Song, Jia Jia, Jia Zeng, Yuxi Zhao, Xianming Liu, Xiaoxian Du, Yansheng Liu, Pei Wang, Bing Zhang, Li Ding, Ana I Robles, Henry Rodriguez, Hu Zhou, Zhen Shao, Lingying Wu, Daming Gao

Faculty, Staff and Students Publications

Although the incidence of cervical cancer (CC) has been reduced in high-income countries due to human papillomavirus (HPV) vaccination and screening strategies, it remains a significant public health issue that poses a threat to women's health in low-income countries. Here, we perform a comprehensive proteogenomic profiling of CC tumors obtained from 139 Chinese women. Integrated proteogenomic analysis links genetic aberrations to downstream pathogenesis-related pathways and reveals the landscape of HPV-associated multi-omic changes. EP300 is found to enhance the acetylation of FOSL2-K222, consequently accelerating the malignant proliferation of CC cells. Proteomic stratification identifies three patient subgroups with distinct features in prognosis, …

Evidence-Based Pathways For Leveling Digital Access In Higher Education During And Beyond The Covid-19 Pandemic, Christopher Ali, Vikki Katz

Communication Faculty Articles and Research

At the height of the COVID-19 pandemic, policymakers’ attention focused heavily on K–12 student connectivity. By contrast, college students were largely “presumed connected,” even as they lost access to campus Wi-Fi, computer labs, and other digital resources. This study asks what lessons were learned and not learned by university administrators when it came to digital inequality on their campuses during the pandemic. To address this question, the article’s authors relied on a series of student surveys and policy analyses. This article offers evidence-based policy recommendations to university leaders for effectively addressing digital inequality among their student populations as we look …

Towards A Comprehensive Metaverse Forensic Framework Based On Technology Task Fit Model, Amna Almutawa, Richard Adeyemi Ikuesan, Huwida Said

All Works

This article introduces a robust metaverse forensic framework designed to facilitate the investigation of cybercrime within the dynamic and complex digital metaverse. In response to the growing potential for nefarious activities in this technological landscape, the framework is meticulously developed and aligned with international standardization, ensuring a comprehensive, reliable, and flexible approach to forensic investigations. Comprising seven distinct phases, including a crucial incident pre-response phase, the framework offers a detailed step-by-step guide that can be readily applied to any virtualized platform. Unlike previous studies that have primarily adapted the existing digital forensic methodologies, this proposed framework fills a critical research …

Fouad Named Chair Of The Ada Council On Scientific Affairs, Brianna Hoge

Browse All News

No abstract provided.

Anemia Is A Disease, Not A Number, Shane C. Coy, Matthew A. Warner

Student Publications

No abstract provided.

Cellular Signatures In Human Blood Track Bone Mineral Density In Postmenopausal Women, Kaichi Kaneko, Jefferson Tsai, Deniece Meñez, Brian Oh, Andrew Junwoo Suh, Seyeon Bae, Masataka Mizuno, Akio Umemoto, Eugenia G. Giannopoulou, Takayuki Fujii, Yaxia Zhang, Emily M. Stein, Richard S. Bockman, Kyung-Hyun Park-Min

Publications and Research

Osteoclasts are the sole bone-resorbing cells and are formed by the fusion of osteoclast precursor cells (OCPs) derived from myeloid lineage cells. Animal studies reveal that circulating OCPs (cOCPs) in blood travel to bone and fuse with bone-resident osteoclasts. However, the characteristics of human cOCPs and their association with bone diseases remain elusive. We have identified and characterized human cOCPs and found a positive association between cOCPs and osteoclast activity. Sorted cOCPs have a higher osteoclastogenic potential than other myeloid cells and effectively differentiate into osteoclasts. cOCPs exhibit distinct morphology and transcriptomic signatures. The frequency of cOCPs in the blood …

Navigating Crisis: The Intersection Of Politics, Culture, And Suicide In South Korea And Japan, Natasha A. Burke

Honors College Theses

Suicide is an important global issue, and there need to be measures put in place to help prevent such a problem. Existing literature finds that culture and politics do significantly impact suicide rates. I assess how the perceptions of suicide differ from culture to culture and how culture plays a role in the rates of suicide and reasons for it. I also examine at how socioeconomic status, unemployment, and economics affect people as well. In this study, I research how politics and culture affect suicide rates in Asia, specifically how politics and culture influence suicide rates in South Korea and …