Evaluating The Duckweeds Lemna Minor And Spirodela Polyrhiza As Alternative Aquatic Hosts For The Spread Of The Bacterial Wilt Pathogen, Ralstonia Solanacearum, Irelynn Smith

Honors Theses

Ralstonia solanacearum is a plant pathogen that causes bacterial wilt disease in major crops such as tomatoes and potatoes. Recently, this bacterium was discovered in floating pennywort (Hydrocotyle ranunculoides) and Pennsylvania smartweed (Polygonum pennysylvanicum), two previously unsuspected aquatic plants. Duckweed is an aquatic plant with a high level of resilience and short doubling time. Common duckweed (Lemna minor) has previously demonstrated its capability as a versatile high-yield infection model for other types of pathogenic bacteria. Given this newfound branch of aquatic hosts and the fact that duckweed is a common pond weed previously identified in several ponds located nearby infected …

Creating A Space For Relaxation And Wellbeing At The University Of South Alabama, Mary Wolf

Honors Theses

A program to provide supplementary support for the mental health and wellness of students at a midsize Southern University by providing a centrally located “relaxation space” for students on campus during the last two weeks of the semester is proposed and tested. A central location was found on campus to host the space. The researcher also developed an online survey for students to review the space. The trial was run for two weeks, and participants were able to access the online survey throughout those weeks. The results of the survey were analyzed to better understand the students’ responses to the …

Barriers In Reporting Sexual Violence On College Campuses, Amber Hartman

Honors Theses

This thesis is designed to examine the underreporting of sexual violence on college campuses by exploring the systemic, cultural, and logistical barriers that hinder victims from disclosing their assault. Using both qualitative and quantitative methodologies, the research identifies three overarching influences for non-reporting. Fear, shame, and lack of resources are presented as the basis of the decision that victims make to not report. Meta-analysis of the research concludes that there is a profound impact of internalized victim-blaming narratives, fear of repercussions and institutional deficiencies in providing accessible support. Recommendations for solutions emphasize creating trauma-informed policies, improving communication and accessibility of …

Comparison Of Two Learning Methodologies: Virtual Reality And Osce Simulation, Connor Blackwell, Tabor Mcgee

Doctoral Projects

Anesthesia education has evolved immensely over the past twenty years, and with the new virtual reality (VR) simulations created by SIMVANA, the exponential growth can continue. The anesthesia program at The University of Southern Mississippi (USM) currently utilizes an educational platform known as the Objective Structured Clinical Examination (OSCE) for their students’ clinical curriculum. With the development of technology and education models, the purpose of the doctoral project is to determine if VR simulation can produce more effective learning than the OSCE modules. To determine the effectiveness, pharmacologic lessons for intraoperative hypotension were administered through both platforms and then tested …

Improving Consistency Of Quality-Of-Life-Assessments In Schizophrenia Patients Through Structured Education For Healthcare Providers, Dorothy Stewart

Doctoral Projects

Schizophrenia is a chronic and debilitating mental disorder that significantly impacts patients' quality of life (QoL). Effective management of schizophrenia requires not only symptom control but also a comprehensive assessment of QoL to guide treatment plans. The Schizophrenia Quality of Life Scale Revision 4 (SQLS-R4) is a specialized tool designed to evaluate the unique challenges faced by patients with schizophrenia. However, inconsistencies in the administration and interpretation of the SQLS-R4 by healthcare providers have led to variability in patient care. This doctoral project aimed to address this gap by implementing a structured educational intervention for healthcare providers that focused on …

Utilization Of Quantitative Monitoring To Promptly Detect And Reduce The Occurrence Of Residual Paralysis In The Post-Anesthesia Care Unit, Kathryn Elizabeth Nokes, Erin Moran Travis

Doctoral Projects

Objective: To evaluate the effectiveness of an educational workshop using an Objective Structured Clinical Examination (OSCE) on quantitative neuromuscular monitoring. The goal was to improve the knowledge and skills among certified registered nurse anesthetists (CRNAs) and student registered nurse anesthetists (SRNAs) in identifying residual paralysis. The specific aim was to determine the effectiveness of quantitative monitoring in the Post Anesthesia Care Unit (PACU).

Background: Residual paralysis following the administration of neuromuscular blocking drugs (NMBDs) is a significant postoperative complication. Neuromuscular blocking drugs (NMBD) facilitate airway management and manipulation of surgical fields. Quantitative monitoring can be crucial in early detection and …

Anti-Inflammatory Potential Of Black Cumin Seed Oil And Its Nanoemulsion Formulation Against Lipopolysaccharide-Induced Liver Injury In Mice, Shady Swidan, Hesham Hafez, Rehab Hosni, Hatem Amin

Pharmacy

Original Article

Anti-inflammatory potential of black cumin seed oil and its nanoemulsion formulation against lipopolysaccharide-induced liver injury in mice

Haffez, Hesham^1,2,✉; Hosni, Rehab³; Swidan, Shady A.⁴; Amin, Hatem K.^1,5

Author Information

¹Biochemistry and Molecular Biology Department, Faculty of Pharmacy, Helwan University, Helwan, 11795, Cairo, Egypt

²Center of Scientific Excellence “Helwan Structural Biology Research”, Helwan University, Helwan, 11795, Cairo, Egypt

³El Sisi Comprehensive Clinic, General Authority for Health Insurance-Giza, Haram, 12556, Giza, Egypt

⁴Department of Pharmaceutics and Pharmaceutical Technology, Faculty of Pharmacy, The British University in Egypt, El-Sherouk, 11837, Cairo, …

Gandy Dancer 13.1 (Fall 2024), Gandy Dancer

Gandy Dancer Archives

Gandy Dancer is a literary magazine, publishing fiction, poetry, creative nonfiction, and visual art. We invite submissions from student writers and artists at all of the SUNY campuses. Edited by students at SUNY Geneseo, Gandy Dancer is published twice yearly. For more information, visit www.gandydancer.org. Gandy Dancer 13.1 is the twenty-fourth issue, published Fall 2024.

Investigation Of Social Networks Upon Academic Performance And Mental Health, Rachel Izenson

Master's Theses

It has been shown that computing students have a statistically significantly lower overall sense of belongingness compared to other science students. A sense of community is important for many reasons. For example, there are studies that show that a student's sense of belonging correlates with improved academic performance. Our research aims to analyze the sense of belonging among computing students at Cal Poly San Luis Obispo through a network science lens. We surveyed for their sense of belonging, as well as their social network, to understand how friendships impact one's sense of belonging. When student responses were split by gender, …

How Millennials Make Investment Decisions: Financial Literacy And Financial Behavior, Dewi Tamara, Anita Maharani

Economics and Finance in Indonesia

This study investigates the effect of financial literacy, financial attitude, risk perception, and financial behavior on investment decisions. Employing a survey method with 342 respondents in Jakarta, the findings reveal that financial literacy has a negative and insignificant effect on investment decisions. In contrast, risk perception plays a crucial role in influencing investment decisions. Furthermore, financial behavior has an indirect mediating effect between financial literacy and risk perception on investment decisions but does not affect financial attitude. This study concludes that risk perception and financial behavior are important factors in investment decisions. Future research may consider incorporating other variables such …

Housing Insecurity Among Black Women Surviving Intimate Partner Violence During The Covid-19 Pandemic: An Intersectional Qualitative Approach, Tiara C. Willie, Sabriya L. Linton, Shannon Whittaker, Karlye A. Phillips, Deja Knight, Mya C. Gray, Gretta Gardner, Nicole Overstreet

Psychology

Background: Housing instability is highly prevalent among intimate partner violence (IPV) survivors, and the coupling consequences of structural racism, sexism, classism, and the COVID-19 pandemic, may create more barriers to safe and adequate housing, specifically for Black women IPV survivors. In particular, the consequences of the COVID-19 pandemic had the potential to amplify disadvantages for Black women IPV survivors, yet very little research has acknowledged it. Therefore, the current study sought to assess the experiences of housing insecurity among Black women experiencing intimate partner violence (IPV) while navigating racism, sexism, and classism during the COVID-19 pandemic. Methods: From January to …

Social Capital And Changes Of Psychologic Distress During Early Stage Of Covid-19 In New Orleans, Kimberly Wu, Erica Doe, Gabriella D. Roude, Jasmine Wallace, Samantha Francois, Lisa Richardson, Katherine P. Theall

Psychology

Here we report on the relationship between measures of social capital, and their association with changes in self-reported measures of psychological distress during the early period of the COVID-19 pandemic. We analyze data from an existing cluster randomized control trial (the Healthy Neighborhoods Project) with 244 participants from New Orleans, Louisiana. Changes in self-reported scores between baseline (January 2019–March 2020) and participant’s second survey (March 20, 2020, and onwards) are calculated. Logistic regression is employed to examine the association between social capital indicators and measures of psychological distress adjusting for key covariates and controlling for residential clustering effects. Participants reporting …

Breast Cancer: Her2-Mutant P53 Cooperation And The Cell-Of-Origin Dependent Dynamics, Abie Williams-Villalobo

Dissertations (2016-Present)

Subtype. Specifically, NCP172 and NCP245 tumors grew faster and were predominantly triple- negative than NCP245. RNA sequencing identified many differentially expressed genes (DEGs) between tumor and mammary gland controls. Ingenuity Pathway Analysis (IPA) of the DEGs revealed that pathways like Deubiquitination, Cell Cycle Checkpoints, RHO GTPase cycle, and HIF1α Signaling were associated with aggressive tumor characteristics, with heightened pathway activity in NCP172 likely contributing to greater growth and invasiveness.

This study further examined how different cells-of-origin contribute to breast cancer heterogeneity by inducing mutant p53 in either mammary myoepithelial or luminal cells. Tumors originating from myoepithelial cells (Tk5) exhibited …

Potential Ethanol Extracts Of Super Red Dragon Fruit Peel And Flesh For Detecting Dental Plaque, Euis R. Yuslianti, Dewi Li. Nasution, Nadya S. Pramita

Journal of Dentomaxillofacial Science

Objective: Dental plaque is a collection of microorganisms that adhere to surface of tooth and can cause various health problems in oral cavity. To detect plaque on surface of teeth, a coloring agent such as a disclosing solution is needed. As an alternative ingredient that does not harm, this study used super red dragon fruit peel and flesh (Hylocereus costaricensis) which is high levels of anthocyanins and natural coloring agents that can be used as alternative materials for detecting plaque on surface of tooth.

Material and Methods: The research methode were quasi-experimental design research with a post-test control …

Assessing The Impact Of An Individual Diabetic Education Program And Big Data App On Three Generations Of Patient Populations, Avery C. Carpenter, Rechendia C. Carpenter, Ester M. Felipe

Doctoral Projects

Diabetes is a chronic condition that affects numerous people worldwide. Diabetic education assists people with understanding the nature of diabetes, its side effects and how to successfully deal with the condition. The doctoral project incorporates finding out how glucose monitoring, prescription administration, dieting propensities, and the significance of customary activities. With proper education the impact on one’s health with this chronic condition can improve for the better.

The nature of this doctoral project is to assess the impact that a diabetic education program and big data app have on three generations. Members of the group partnered with Hutton Healthcare in …

Chain Extension Of Blocked Isocyanates For The Creation Of Covalent Adaptable Networks, Catherine Sarantes

Dissertations

From mattresses to car coatings, polyurethanes and polyureas (PUs) are ubiquitous thermoset materials with tunable thermo-mechanical performance. This tunability is afforded through the extent of crosslinking or covalent linkages established by the formation of urea bonds. Traditionally, urea bonds are highly stable yet through the blocked isocyanate, hindered urea bond (HUB) mechanism this bond is thermally labile allowing for re-processing of normally non-recyclable PU materials. The overarching focus of my dissertation is the exploration synthetic pathways to access secondary diamines to enable re-processing of covalent adaptable networks (CANs) with tunable re-processing through the diamine moiety and the molecular weight of …

Victim Impact Statements In Mass Tort Bankruptcy Cases: Balancing Chapter 11'S Proceduralism With Tort Law's Commitment To Nonmonetary Recovery, Julia Boccagno

Denver Law Review

Bankruptcy has evolved into tortfeasors’ choice of law for resolving mass tort litigation. The United States Bankruptcy Code is equipped with procedural devices designed to maximize litigants’ financial recovery and enhance judicial efficiency. Although bankruptcy procedures aim to resolve widespread liability and open the courthouse doors to litigants who may not otherwise recover, they simultaneously overlook the nonmonetary and dignitary objectives underlying tort law. This Note uses the Supreme Court’s recent decision in Harrington v. Purdue Pharma—a high-profile example of mass tort litigation resolved through bankruptcy—to examine the extent to which bankruptcy procedures are unable to fulfill the nonmonetary objectives …

Toxic Narratives, Toxic Communities, And Enforcement Of Environmental (In)Justice, Alyse Bertenthal

Washington Law Review

The United States has committed to enforce environmental justice in ways it never has before. A spate of new policies aims to increase resources for environmental agencies’ enforcement sections, improve training for environmental enforcement staff, and ensure community engagement in environmental enforcement decision-making. Yet there exists mounting evidence that enforcement of environmental laws happens less frequently and less vigorously in low-income and minoritized communities.

We need to understand why that is happening. Many commentators, opining from a distance, point to insufficient resources for environmental enforcement and legal and political constraints on environmental agencies. While not discounting these reasons, this Article …

From Preparation To Practice: How Principals Engage Families In Diverse School Settings, Morgan Garner

Ed.D. Dissertations

Rural, urban, and suburban school principals faced distinct challenges in engaging families and fostering positive school climates. Recognizing the need for tailored leadership strategies, it was essential for principal preparation programs to provide context-specific training. The purpose of basic interpretive qualitative study was to explore the relationship between principals’ approaches to school management in rural, urban, and suburban schools and how their preparation programs facilitated the development of these approaches. Forty-six principals participated in the study, and I collected data through a questionnaire based on a parental involvement framework. The analysis revealed key differences in strategies; rural principals emphasized community …

Apoa2 Increases Cholesterol Efflux Capacity To Plasma Hdl By Displacing The C-Terminus Of Resident Apoa1, Snigdha Sarkar, Jamie Morris, Youngki You, Hannah Sexmith, Scott E. Street, Stephanie M. Thibert, Isaac K. Attah, Chelsea M. Hutchinson Bunch, Irina V. Novikova, James E. Evans, Amy S. Shah, Scott M. Gordon, Jere P. Segrest, Karin E. Bornfeldt, Tomas Vaisar, Jay W. Heinecke, W. Sean Davidson, John T. Melchior

Saha Cardiovascular Research Center Faculty Publications

Abstract The ability of high-density lipoprotein (HDL) to promote cellular cholesterol efflux is a more robust predictor of cardiovascular disease protection than HDL-cholesterol levels in plasma. Previously, we found that lipidated HDL containing both apolipoprotein A-I (APOA1) and A-II (APOA2) promotes cholesterol efflux via the ATP-binding cassette transporter (ABCA1). In the current study, we directly added purified, lipid-free APOA2 to human plasma and found a dose-dependent increase in whole plasma cholesterol efflux capacity. APOA2 likewise increased the cholesterol efflux capacity of isolated HDL with the maximum effect occurring when equal masses of APOA1 and APOA2 coexisted on the particles. Follow-up …

Untargeted Lipidomics Reveals Novel Hdl Metabotypes And Lipid-Clinical Correlates, Peer W. F. Karmaus, Scott M. Gordon, Marcus Y. Chen, Alison A. Motsinger-Reif, Rodney W. Snyder, Timothy R. Fennell, Suramya Waidyanatha, Reshan A. Fernando, Alan T. Remaley, Michael B. Fessler

Saha Cardiovascular Research Center Faculty Publications

Plasma high-density lipoprotein (HDL), originally studied for its role in lipid transport, is now appreciated to have wide-ranging biological functions that become defective during disease. While >200 lipids have collectively been detected in HDL, published HDL lipidomic analyses in different diseases have commonly been targeted to prespecified subsets of lipids. Here, we report the results of untargeted lipidomic analysis of HDL isolated from 101 subjects referred for computed tomographic coronary imaging for whom multiple additional clinical and lipoprotein metadata were measured. Unsupervised clustering of the total HDL lipidome revealed that the subjects fell into one of two discrete groups, herein …

Tissue Plasminogen Activator Associated Pulmonary Hemorrhage In Patient With Acta2-Associated Arteriopathy, Travis G. Hughes, Mark A. Wurth, Mary Burchett Sheppard

Saha Cardiovascular Research Center Faculty Publications

Pulmonary hemorrhage after administration of tissue plasminogen activator (tPA) is a rare complication. We present a 15- year-old boy with a heterozygous pathogenic variant in ACTA2 who presented with right brachial artery aneurysm thrombosis treated initially with tPA, resulting in pulmonary hemorrhage. We hypothesize that the underlying pulmonary abnormalities caused by the pathogenic ACTA2 variant may be a risk factor for pulmonary hemorrhage after tPA administration. (J Vasc Surg Cases Innov Tech 2024;10:101558.)

An Interview With Lucia Lotempio, Jordyn Stinar

Gandy Dancer Archives

No abstract provided.

Differentiating Mycosis Fungoides Lesions From Their Mimickers Clinically And Histologically: A Single Tertiary Center Retrospective Analysis In Saudi Arabia, Fatimah M. Budair, Ahmed A. Alsayyah, Omar M. Alakloby

Saudi Medical Journal

Objectives: To identify the clinical and histological features of MF that can assist in distinguishing MF from MF-mimicking cases. Although mycosis fungoides (MF) is the most common subtype of cutaneous T-cell lymphoma, clinicopathological correlations are required to establish an accurate diagnosis, which are currently lacking. Methods: This retrospective observational study evaluated the clinical presentations, characteristics, and histological features of 56 patients with suspected MF who presented to our clinic between January 2018 and August 2022. Immunohistochemistry was performed, and the loss of CD5 and CD7 T-cells and T-cell receptor rearrangement was evaluated. Results: Overall, 34 patients were diagnosed with MF, …

Beauty Beyond Barbed Wire: Chiura Obata’S Perspective Of The Horizon, Bri Carlson

Theses

Depictions of the environment are an integral part of American art history because they convey cultural relationships of all who inhabited the land. The environment is often a stagnant force that harbors lifetimes of human history. One of these histories is the incarceration of about 120,000 Japanese immigrants and American citizens in 1942 after the bombing of Pearl Harbor. They were forced to evacuate their homes, lives, and families to live in detention centers and prison camps where living conditions were subpar. Many turned to art making to cope, and some artists used their work to silently protest and visually …

Endolysosomal Mechanisms Of Sars-Cov-2 Spike-Induced Inflammatory Response And Senescence In Human Astrocytes, Wendie Ann Hasler

Theses and Dissertations

The COVID-19 pandemic has led to widespread reports of prolonged neurological symptoms in individuals who have recovered from the acute phase of the infection. These persistent symptoms, collectively termed Neuro-PASC (Neurological Post-Acute Sequelae of SARS-CoV-2 infection), range from cognitive impairments to mood disturbances and other neuroinflammatory issues. Pathological features of Neuro-PASC include vascular impairment, neuroinflammation, and neurodegeneration. One leading hypothesis for the development of Neuro-PASC is the persistent of SARS-CoV-2 viral factors. Post-mortem evidence indicates that the spike protein of SARS-CoV-2 is consistently found in the brains of individuals who died with COVID-19, indicating that viral components can interact with …

Detection Of Apiary Sites From Remote Imagery, Ning Li

Theses and Dissertations

Honey bees are essential for honey production and pollination services, but their colonies have been declining despite increasing demand. This decline may be due to various factors, including habitat loss, altered land use, climate shifts, and pesticide exposure. In order to assess the quantity and quality of habitats for honey bees and determine their availability and suitability for supporting bee colonies, it is crucial to identify the spatial location of registered apiary sites being used. However, such data is not available, which makes it a challenge for researchers in the field to further advance honey bee-related investigations. In my study, …

Low-Temperature Dual Balance Electrodynamic Trap (Lt-Dbet) For Single Microparticle Aerosol Studies, Victor Oyebamiji Ojo

Theses and Dissertations

Atmospheric aerosol processes regulate our climate through light scattering and cloud formation, which are governed by their physicochemical properties. Despite their climate impacts, important individual particle properties are difficult to measure at controlled temperatures relevant to the troposphere. This study presents the Low-Temperature Dual Balance Electrodynamic Trap (LT-DBET), a commercial DBET from MicroLev LLC, modified with a copper tubing network and a recirculating chiller to achieve temperature control as low as -5 ⁰C, which is suitable for heterogenous freezing using AgI. Aerosol microdroplet growth via water uptake is indirectly measured using a feedback loop, which continuously applies balancing voltages proportional …

Evaluation Of Hydrogen Storage Potential In Depelted Hydrocarbon Formations: A Case Study Of The Middle Bakken Member In The Antelope Field, Williston Basin, North Dakota, Grace Oluwakemisola Taiwo

Theses and Dissertations

Hydrogen, as a low-emission fuel and energy carrier, plays a crucial role in stabilizing renewable energy variability amid global decarbonization efforts. Subsurface storage, uniquely secure against threats such as severe weather, military conflicts, fires, and acts of terrorism, is critical for large-scale hydrogen applications and addressing the intermittency of renewable resources. North Dakota, represents a classic example of a state where reliance on fossil fuels drives significant greenhouse gas emissions. The state also hosts the Bakken Formation, an important hydrocarbon formation where depleted or nearly depleted wells exacerbate environmental challenges through potential fugitive emissions. This study therefore investigates the feasibility …

Modeling Instrument Design Risks In Medical Device Reprocessing, Manuel Andres Gutierrez

All Dissertations

Medical device reprocessing is an essential practice in healthcare delivery. While FDA regulations require device manufacturers to develop and validate reprocessing procedures, the increasing complexity of medical device designs and their use environments can increase the risks of inadequate reprocessing and associated device malfunctions and potential patient injury. While some design features present known difficulties for reprocessing, critical information needed to define relative risks or feature-specific parameters that increase or decrease risks of inadequate reprocessing is lacking. There is an urgent need for tools to quantify and predict reprocessing risks associated with design features used in surgical instruments.

The broad …