Digital Commons Network^™

Cerebrovascular Markers Of Wmh And Infarcts In Adni: A Historical Perspective And Future Directions, Pauline Maillard, Evan Fletcher, Owen Carmichael, Christopher Schwarz, Stephan Seiler, Charles Decarli

Clinical Research Faculty Publications

White matter hyperintensities (WMH) and infarcts found on magnetic resonance imaging (MR infarcts) are common biomarkers of cerebrovascular disease. In this review, we summarize the methods, publications, and conclusions stemming from the Alzheimer's Disease Neuroimaging Initiative (ADNI) related to these measures. We combine analysis of WMH and MR infarct data from across the three main ADNI cohorts with a review of existing literature discussing new methodologies and scientific findings derived from these data. Although ADNI inclusion criteria were designed to minimize vascular risk factors and disease, data across all the ADNI cohorts found consistent trends of increasing WMH volumes associated …

Blood And Mri Biomarkers Of Mild Traumatic Brain Injury In Non-Concussed Collegiate Football Players, Eunhan Cho, Joshua Granger, Bailey Theall, Nathan Lemoine, Derek Calvert, Jack Marucci, Shelly Mullenix, Hollis O’Neal, Tomas Jacome, Brian A. Irving, Neil M. Johannsen, Owen Carmichael, Guillaume Spielmann

Clinical Research Faculty Publications

Football has one of the highest incidence rates of mild traumatic brain injury (mTBI) among contact sports; however, the effects of repeated sub-concussive head impacts on brain structure and function remain under-studied. We assessed the association between biomarkers of mTBI and structural and functional MRI scans over an entire season among non-concussed NCAA Division I linemen and non-linemen. Concentrations of S100B, GFAP, BDNF, NFL, and NSE were assessed in 48 collegiate football players (32 linemen; 16 non-linemen) before the start of pre-season training (pre-camp), at the end of pre-season training (pre-season), and at the end of the competitive season (post-season). …

Metabarcoding The Arctic Ocean Helps Reveal Its Hidden Microbial Community Composition, Rafet Çağrı Öztürk, Yahya Terzi, Sheila Rodríguez-Machado, Ersan Başar, Ali Muzaffer Feyzioğlu, Dilek Ustaoğlu, Ertuğrul Ağırbaş, Prosanta Chakrabarty

Faculty Publications

The Arctic Ocean supports a unique and dynamic microbial community, yet its composition, structure, and response to environmental shifts remain incompletely understood. In this study, 16S rRNA gene metabarcoding (targeting the V3-V4 and V4-V5 hypervariable regions) was used to assess surface water microbial diversity across 20 stations in the Barents Sea, focusing on latitudinal variations within two contrasting current systems: the West Spitsbergen Current (WSC) and the East Spitsbergen Current (ESC). Our results showed that the microbial community is dominated by three primary families—Pseudoalteromonadaceae, Moraxellaceae, and Flavobacteriaceae (14.20%). Comparative analysis of the V3-V4 and V4-V5 regions reveals that each region …

Identification And Expression Analysis Of Phosphate Transporter 1 (Pht1) Genes In The Highly Phosphorus-Use-Efficient Hakea Prostrata (Proteaceae), Benjamin J. Nestor, Toby Bird, Anita A. Severn-Ellis, Philipp E. Bayer, Kosala Ranathunge, M. Asaduzzaman Prodhan, Maheshi Dassanayake, Jacqueline Batley, David Edwards, Hans Lambers, Patrick M. Finnegan

Faculty Publications

Heavy and costly use of phosphorus (P) fertiliser is often needed to achieve high crop yields, but only a small amount of applied P fertiliser is available to most crop plants. Hakea prostrata (Proteaceae) is endemic to the P-impoverished landscape of southwest Australia and has several P-saving traits. We identified 16 members of the Phosphate Transporter 1 (PHT1) gene family (HpPHT1;1-HpPHT1;12d) in a long-read genome assembly of H. prostrata. Based on phylogenetics, sequence structure and expression patterns, we classified HpPHT1;1 as potentially involved in Pi uptake from soil and HpPHT1;8 and HpPHT1;9 as potentially involved in Pi uptake and root-to-shoot …

Creating A Bio-Based Circular Economy From Louisiana Sugarcane Byproducts, G. Aita, D. Bhatnagar, G. O. Bruni, M. Deliberto, G. Eggleston, A. Finger, K. Gravois, M. Isied, W. Judice, K. T. Klasson, I. M. Lima, J. L. Purswell, M. Souliman, E. Terrell, B. S. Tubaña, H. L. Waguespack, J. J. Wang, P. M. White

Faculty Publications

Abstract: Sugarcane (Saccharum officinarum) is Louisiana's number one row crop. Growing and processing sugarcane produces significant amounts of byproducts, including bagasse, crop residue, molasses, filter-press mud, and boiler fly ash. These products represent an important opportunity to generate value-added and specialty products and enhance sugarcane's sustainability by facilitating a circular economy, where agricultural by-products are reused instead of disposing them (linear economy), in order to reduce resource use and energy demand. Examples of value-added products range from biochar, construction materials, animal feed, biofuels, nanoparticles, and fertilizer. Paramount to the success of the bio-based circular economy is creating useful products that …

Improving Winter Survival Of Interspecific Hybrid Bermudagrass In The Mid-Atlantic Region Through Cultural Practices, Joseph R. Doherty, Wendell J. Hutchens, Jordan C. Booth, David S. Mccall, Michael V. Battaglia, Eric J. Deboer, Joseph A. Roberts

Faculty Publications

Winter injury can cause significant loss of hybrid bermudagrasses [Cynodon dactylon (L.) Pers. × C. transvaalensis Burtt-Davy] in the transition zone. Current research has focused on high-value, low-acreage areas like putting greens, but those practices are impractical to implement on golf course fairways. To that end, multi-year research projects were conducted at three sites across Maryland and Virginia to investigate the influence of annual N fertility [2.0 lb N 1000 ft−2 (early summer application) or 4.0 lb N 1000 ft−2 (split applied early and late summer)] across multiple fall mowing heights (0.5 inches, 0.8 inches, or 1 inch) and to …

Management Strategies For Preventing And Recovering From Bermudagrass Winterkill, W. J. Hutchens, T. Q. Carr, A. J. Patton, C. A. Bigelow, E. J. Deboer, J. M. Goatley, D. L. Martin, D. S. Mccall, G. L. Miller, J. S. Powlen, M. D. Richardson, M. Xiang

Faculty Publications

Bermudagrass (Cynodon spp. Rich) is a warm-season grass that is widely planted throughout tropical, sub-tropical, and even temperate climates, and it generally requires fewer inputs than most cool-season turfgrasses. In recent years, the area of adaptation for bermudagrass has progressively expanded to cooler climates due to the development of more cold-tolerant cultivars. The expanded area of adaptation as well as the reduced inputs required to maintain healthy turfgrass have made bermudagrass a popular choice in areas of marginal adaptation. In these areas, the greatest threat to bermudagrass health and survivability is winterkill. This management guide seeks to describe winterkill: what …

Labrad : Vol 49, Issue 2 - December 2024, Aga Khan University Hospital, Karachi

LABRAD - Departments of Pathology & Laboratory Medicine and Radiology Archives

• EDITORIAL
• ARTICLES
• Anti-Glomerular Basement Membrane (GBM) Disease: Pathogenesis, Presentation, and Diagnostic Insights
• Advanced Total Laboratory Automation (TLA) Workflow: A Comprehensive Approach towards High-Throughput Analyzers in Clinical Chemistry
• Precision Under Pressure: Challenges in Therapeutic Drug Monitoring for Immunosuppressants
• Frozen Section: Diagnostic Accuracy, Pitfalls and Use of Digital Pathology
• Working Environment Perspective of a Learner
• AI Training: A Must-Have Skill for Tomorrow’s Radiologists
• Challenges in Blood Supply: Importance of Voluntary Donations
• Leadership Skills and Emotional Intelligence For Professional Capacity Building in Histopathology – A Broad Perspective
• Factor VIII and XI Deficiency; A Finding That Could Have Been Missed-A Case Report
• Accelerated Phase …

Spectrometric Detection Of Microplastics In The Environment: A Novel Approach Using Hyperspectral Imaging System, Mansurat Abdulmalik Ali

Theses and Dissertations

Microplastics (MPs), defined as plastic particles ranging from 1 μm to 5 mm, have emerged as one of the significant environmental contaminants due to their widespread presence in terrestrial and aquatic ecosystems. MPs originate from primary sources, such as industrial pre-production pellets and microbeads in personal care products, or secondary sources, such as the breakdown of larger plastic particles. Their persistence in the environment is due to their resistance to degradation and capacity to transport toxic substances and pathogens. These characteristics raise concerns about their ecological impacts and potential entry into food chains, ultimately affecting human health. Despite extensive research …

Population Genetics Of Deer In The Northern Great Plains, Usa, Sarah Elizabeth Daman

Theses and Dissertations

Deer are currently under threat of chronic wasting disease (CWD) throughout North America. With CWD distribution increasing globally, understanding the spread of the disease is paramount for the effective management and conservation of deer populations. Conservation genomics has been shown as an effective method to study the behavior and movement of individuals on the landscape at a broad spatial scale. This approach allows for a multi-state evaluation of habitat and landscape features that may influence the dispersals and subsequent gene flow between populations. This study was designed to assess the genetic population structuring of deer within North Dakota and surrounding …

Personality Across Realities: Correlations Between Personality Profiles And Preferences Within Roleplaying Games, Brittany Lee Mancha

Theses and Dissertations

Clinically maladaptive behaviors and personality types have been studied within gamers, both those who play video games and those who roleplay in tabletop games. However, the connection between personality types and the preferences of the players themselves in what and how they roleplay is just barely being studied. Personality traits, such as extraversion/introversion and motivation by pain or pleasure, may be both influencing the gameplay decisions and preferences of players, and vice versa. A total of 500 respondents completed the Millon Index of Personality Styles, Revised (MIPS-R), followed by a demographics survey and finally a survey assessing Dungeons and Dragons', …

Applied Indigenous Knowledge Translation: Naatookyookaasii, Lynn Marie Mad Plume

Theses and Dissertations

This dissertation portfolio comprises three projects aimed at advancing Indigenous health and integrating cultural perspectives into research and practice. Guided by principles of community engagement and ethical research practices, these projects align closely with my career goals in Indigenous health policy and research. The first project, "Measuring Wellness Through Indigenous Partnerships," is a scoping review that examines global Indigenous wellness measures and assesses community involvement in defining measures of wellness. This review informs future practice directions and supports my advocacy for culturally responsive methodology. The second project, "Reciprocal Facilitation: Protocols and Practices for Listening Sessions with Tribal Communities," introduces a …

Handheld Multimodal Point Spectroscopy, Rgb Imaging, And Fusion Artificial Intelligence To Determine The Species And Freshness Of Fish Fillets, Mitchell Sueker

Theses and Dissertations

When fish species are mislabeled and the fish’s freshness is inaccurately represented, health, environmental, and economic problems can arise for both consumers and the fish industry. Fish are some of the easier foods to mislabel, as the processing of whole fish to fillets makes the visual identification of the species and freshness assessment more challenging. Due to the shortcomings of the current industry standards, confirmed by our interviews with over 20 professionals in all fish supply chain nodes, developing a system that can provide accurate and rapid on-site fraud detection is of necessity. In an attempt to meet these needs, …

"I Can Give You Something For That": Exploring The Medical Paradigm In Mental Health Through Contemporary American Literature, Brooke Pierson

Masters Theses and Doctoral Dissertations

In this paper, I analyze two contemporary fiction novels, My Year of Rest and Relaxation by Ottessa Moshfegh and My Dark Vanessa by Kate Elizabeth Russell, through the lens of the 5th edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-5). Moshfegh satirically critiques diagnostic psychiatry as easily exploitable, and suggests that instead of seeking asylum from pain, we should remind ourselves that happiness and pain exist in harmony; that pain is a part of life. Russell suggests the DSM-5 is imperative to understanding traumatic experiences and the mental disorders which arise from them, such as PTSD. Russell …

Radial, Vortex, And Spiral Solutions To The Nonlinear Schrödinger Equation And Other Reaction--Diffusion Systems, James Redmon Cummins

Masters Theses and Doctoral Dissertations

This dissertation explores various solutions to nonlinear reaction-diffusion systems, focusing primarily on the nonlinear Schrödinger equation. Three types of solutions are investigated: radial solutions (with no angular dependence), vortex solutions (with angular dependence but no radial phase dependence), and spiral solutions (which have radial phase dependence). The study considers free particles without potential and trapped particles inside the cylindrical potential with an impenetrable barrier. We show that spiral solutions to the nonlinear Schrödinger equation only exist for a radially constant phase by considering a related system of nonlinear ordinary differential equations. This system is shown to be a special case …

The War Within: Mexican Drug Cartels And The Impact Of The Drug Trade On Society And Governance, Haris Mohammad

Masters Theses

This thesis examines the origins, activities, and societal impacts of Mexican drug cartels, while assessing the effectiveness of governmental and international responses to their development and influence. This thesis examines the evolution of the cartels, starting with their collaboration with traffickers in Colombia and concluding with their supremacy in the global drug trade. The investigation elucidates the social and political factors that have facilitated their growth. These factors include pervasive corruption, economic disparities, and inadequate governance, all of which have fostered an environment conducive to the emergence of cartels.

This thesis examines the detrimental effects of cartel involvement on Mexican …

Exploring Diet Quality, Food Insecurity, And Health Status Among Utah Residents, Palak Gupta, Lendel Narine

Journal of Human Sciences and Extension

A lower-quality diet is a significant contributor to preventable mortality worldwide. This study investigated the intricate relationships between diet quality, food insecurity, and health status among residents in Utah. Using a cross-sectional survey design with a sample size of 1,522 participants, data were collected through an online survey focusing on household characteristics, diet quality, health status, and food security. The primary exposure, household food insecurity, was assessed using a validated 6-item scale, while diet quality was measured through a modified Rapid Eating Assessment for Participants– Shortened Version (REAP-S). The findings revealed an association between very low food security and poor …

Personal Protective Equipment For Minoritized U.S. Agricultural Farmworkers: Community-Based Efforts During The Pandemic & Implications For Extension, Helen Trejo

Journal of Human Sciences and Extension

There are an estimated 2 million farmworkers who are essential to the food system in the United States; however, they are exposed to hazardous environmental conditions with limited access and/or use of Personal Protective Equipment (PPE). The primary purpose of this research is to evaluate community-based organizational efforts to provide farmworkers with apparel-textile basic needs, such as face masks. A primary goal is to address the research gap regarding common environmental factors that impact farmworkers, including pesticides and the pandemic, their use of available PPE, and community-based efforts to improve access to face masks as basic PPE. We consider the …

Extension Partnerships For Innovative Programming: A Community-Based Training On Artificial Intelligence For Workforce Development, Paul A. Hill, Lendel K. Narine, Jordan L. Rushton, Clint J. Reid

Journal of Human Sciences and Extension

The AI Training Series was Washington County, Utah’s first community education offering on the topic of generative AI (GenAI). The training provided community members with an overview of the capabilities and advantages of GenAI and assisted them in making informed technology adoption decisions. Utah State University Extension partnered with Dixie Technical College and Zonos, a software company, to evaluate the effectiveness of the learning experience based on anticipated outcomes. Results showed the training was effective for disseminating information and advancing knowledge on the topic of GenAI. However, students’ intentions to adopt AI were lower than expected due to perceived barriers …

Using The Perspectives Of Kentucky Family And Consumer Sciences Extension Agents To Develop A Sustainable Eating Curriculum, Lindley Barker, Heather Norman-Burgdolf, Annie Koempel, Katie Pickford, Tammy Stephenson, Dawn Brewer

Journal of Human Sciences and Extension

Sustainable eating may benefit both the environment and human health. Currently, no Extension programs addressing healthy and sustainable eating are available that target adults in communities. Since sustainable eating is a sensitive topic, this project engaged Family and Consumer Sciences (FCS) Extension agents in Kentucky, to garner their community expertise and perspectives on sustainable eating to help develop an appropriate Extension curriculum. By following the Curriculum Development Process for Cooperative Extension Programming model, we involved FCS agents in developing and reviewing a sustainable eating curriculum. The proposed curriculum included content that reflected sustainable eating principles of reducing overconsumption of foods, …

The Climate-Immigration Crisis: Recognizing Climate Refugees, Lauren K. Sensiba

Undergraduate Honors Thesis Collection

Christine Gibb and James Ford explain concepts such as migration flows and ‘climate migrants’ as consequences of global climate change, which is a consequence of globalization (Gibb et al., 1-9; Yayboke, 2021; White House, 2021). In their recent study, they examine the intersections of climate change, migration, and international law to advocate for the recognition of “climate migrants” within the United Nations Framework Convention on Climate Change (UNFCCC) and suggest a new framework for establishing the institutional groundwork for such recognition (Gibb et al., 8-9). Gibb and Ford propose that establishing such legal recognition could create a framework to protect …

Synthesis Of Novel Chromenone Esters For Biochemical Assays, Andrew Dean Helmerich

Undergraduate Honors Thesis Collection

This project details the synthesis of a variety of novel chromenone esters to be used as enzymatic probes. A robust, initial library of 22 chromenone esters was successfully synthesized with differences in chain length, branching, and the incorporation of cyclic and heteroatomic moieties. These new chromenones were fully characterized by 1HNMR, 13CNMR, DEPT HRMS, 19FNMR, and HSQC. The utility of these compounds comes from the fact that they will fluoresce upon cleavage of the ester; thus, this property makes them ideal candidates to be used in the monitoring of enzymatic activity of esterases. Elucidating the enzyme-substrate structure activity relationship (SAR) …

From Crisis To Prevention: Mining Big Data For Public Health Insights During The Flint Water Crisis, Charles Knoble, Gift Fabolude, Anvy Vu, Danlin Yu

Department of Earth and Environmental Studies Faculty Scholarship and Creative Works

This study investigates the utility of Google Trends and Google Search data in retrospectively analyzing the Flint Water Crisis, a significant public health event. By examining keywords relevant to the crisis, such as “lead,” “bottled water,” “water filters,” “pneumonia,” and “Legionnaires’ Disease,” we aimed to uncover patterns in public awareness and response during a public crisis and explore how such awareness and responses could potentially aid in reducing the risk of similar crises in the future. Our analysis reveals a clear correlation between search frequencies and the crisis timeline, with spikes in search terms corresponding to key events. This suggests …

Evaluating The Success Of A Relocated Mussel Community In The Lower Sulphur River, Texas, Rachel M. Leicher

Biology Theses

Conservation efforts to preserve freshwater mussel communities have become more common as these animals become increasingly threatened by their changing habitats. As humans continue to shape and change the world around them, aquatic species living in modified and disturbed water systems can be negatively impacted leading to decline of the ecosystem. During disturbance events involving a stream, river, or pond, the relocation of affected mussel beds is becoming more widespread. Although there are few of these studies, many of those that have been conducted are seen as successful in relocating and conserving their mussel communities. This study focuses on detection …

Blinding Of Transcranial Direct Current Stimulation Is Compromised In Typically Developing Children Compared To Young Adults, Sophia Bertrand, Tonya Rich, Samuel Nemanich

Occupational Therapy Faculty Research and Publications

Achieving successful blinding is a persistent challenge for clinical trials involving transcranial direct current stimulation. Studies involving populations with increased sensory sensitivity, such as children, could be at risk for increased bias from inadequate blinding due to unique sensation of stimulation relative to adults. The objectives of this study were 1) To examine differences in transcranial stimulation blinding between children and young adults and its relationship to sensory sensitivity. 2) To test the efficacy of an ActiSham protocol for participant blinding, compared to a traditional sham protocol. Typically developing right-handed children (N = 12, 5–14 yr) and young adults (N …

Assessing The Critical Factors Influencing Worker Safety In Roadway Work Zones, Bahaa Chammout, Muaz O. Ahmed, Islam El-Adaway

Civil, Architectural and Environmental Engineering Faculty Research & Creative Works

Ongoing roadway construction and maintenance activities are essential for sustaining and improving infrastructure. Nonetheless, work zones in the United States continue to experience concerning frequencies of occupational and traffic accidents. Previous research highlighted multiple factors influencing work zone safety, yet their relative impact and importance remain unclear. This study addresses this gap following a multistep methodology. First, 32 safety factors were identified through an extensive literature review in a previous study. Second, a survey was administered among 298 professionals from diverse backgrounds, with an average of 17.75 years of construction experience and 13.78 years of work zone experience, to assess …

Condition And Management Futures In A Quaking Aspen Recreation Area. Final Report To Snyderville Basin Special Recreation District, Paul C. Rogers, Georgie Corkery, Anna B. Miller

Aspen Bibliography

In partnership with Snyderville Basin Special Recreation District (SBSRD), we undertook a study of ecological conditions and user preferences within a quaking aspen recreational destination forest. The location, in two sections know as Run-A-Muk and Right Turn Sage (RAM/RTS), has experienced some forest die-off in the principally aspen dominated forest dissected by ski, bike, and hiking trails. Graduate student Georgie Corkery led the study and successfully completed a Master's degree, in addition to providing needed information to SBSRD regarding the status, uses, and preferred actions at this facility. Key outcomes regarding aspen conditions include assigning causal factors—ungulate browsing and elevated …

Napa Valley Certified Organic Viticulture Napa Valley Vineyards Go Green: Transitioning To Organic Cultivation, Eric E. Tapia

Undergraduate Honors Theses

The shift to sustainable agriculture in Napa Valley necessitates certified organic vineyards among wine industry stakeholders to facilitate systemic change. Nonetheless, numerous impediments—such as fiscal constraints, inadequate access to information, and agricultural education—are intended to address these barriers for fostering an environmental stewardship program focused on innovation and sustainability. The methods employed to investigate the transition to organic vineyards include qualitative and quantitative approaches, such as interviews with vintners and data analysis of annual crop yields and the economic impact of certified organic vineyards in Napa Valley. The investigation reveals that vineyard proprietors face significant early challenges, including a steep …

Unboxing The Balikbayan: Filipino Third Culture Kids' Sense Of Identity And Belonging Upon Repatriation, Zayda De Guzman

Undergraduate Honors Theses

Third Culture Kids (TCKs), or children who grow up in a country different from their parent’s home country, have a unique identity formation is attributed to their mobile upbringing, and is described as “rootless” due to their sense of identity and belonging going past a geographical place. Due to their upbringing, TCKs often struggle with repatriation distress, finding it difficult to maintain a sense of belonging upon returning to their passport country. While TCKs have garnered significant attention from scholars, most of that has been directed towards TCKs from Western countries, such as the United States. This thesis explores how …

Sustainability Spotlight, Hanley Sustainability Institute

Hanley Sustainability Institute Newsletter

No abstract provided.